BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
5'-O-Benzoyl-2',3'-di-O-acetyl-4'-C-fluoromethyluridine is a potent biomedicine used in the research of viral infections, specifically targeting RNA viruses. This compound exhibiting antiviral properties by inhibiting viral RNA synthesis and replication. Grades: ≥95%. Molecular formula: C21H21FN2O9. Mole weight: 464.40.
5'-O-Benzoyl-2'-O,4'-C-methyleneuridine
5'-O-Benzoyl-2'-O,4'-C-methyleneuridine is a paramount compound having application in the research and development of altered nucleosides, showcasing tremendous potential as compounds research of viral afflictions and malignant tumors. Synonyms: 2,4(1H,3H)-Pyrimidinedione, 1-[2,5-anhydro-4-C-[(benzoyloxy)methyl]-α-L-lyxofuranosyl]-; [(1R,3R,4R,7S)-3-(2,4-dioxopyrimidin-1-yl)-7-hydroxy-2,5-dioxabicyclo[2.2.1]heptan-1-yl]methyl benzoate; 2'-O,4'-Methylene-5'-O-benzoyluridine. Grades: ≥95%. CAS No. 293751-31-2. Molecular formula: C17H16N2O7. Mole weight: 360.32.
5'-O-Benzoyl-3'-O-(4-methoxybenzoyl)-2'-O,4'-C-methyleneuridine, renowned for its remarkable efficacy against RNA viruses such as influenza and hepatitis C, stands as a powerful antiviral agent within the biomedical realm. Its profound impact lies in disrupting viral RNA synthesis, effectively impeding the replication process. Grades: ≥95%. Molecular formula: C25H22N2O9. Mole weight: 494.46.
5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-N-methyladenosine is a 5'-O-(4,4'-Dimethoxytriphenylmethy) substitued derivative of the 2'-deoxy N-methyl analogue of Adenosine. It is used in the preparation of oligonucleotides containing N6-methyladenine residues in the GATC site. Synonyms: 5'-O-DMTr-N6-methyl-2'-deoxyadenosine; 5'-O-(4,4'-Dimethoxytriphenylmethyl)-N6-methyl-2'-deoxyadenosine; 5'-O-DMT-2'-deoxy-N-methyl-adenosine; (2R, 3S, 5R)-2- ( (Bis (4-methoxyphenyl) (phenyl)methoxy)methyl)-5- (6- (methylamino)-9H-purin-9-yl)tetrahydrofuran-3-ol; N6-Methyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyadenosine. Grades: ≥95%. CAS No. 98056-69-0. Molecular formula: C32H33N5O5. Mole weight: 567.63.
5'-O-(Dimethoxytrityl)-2'-O-methylinosine is an indispensable compound employed in the biomedical industry, showcasing considerable promise as a research tool for diverse afflictions and maladies. With profound implications in drug development, it enables the precise modulation of molecular pathways and gene expressions. The multifaceted utilization of this compound extends to the realm of research of cancer, viral infections and neurological impairments. Synonyms: 5'-O-DMT-2'-O-METHYL-INOSINE; 5'-O-(DIMETHOXYTRITYL)-2'-O-METHYLINOSINE; 5/'-O-(DIMETHOXYTRITYL)-2/'-O-METHYLINOSINE; 9- ( (2R, 3R, 4R, 5R)-5- ( (Bis (4-methoxyphenyl) (phenyl)methoxy)methyl)-4-hydroxy-3-methoxytetrahydrofuran-2-yl)-9H-purin-6-ol; 9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxy-3-methoxyoxolan-2-yl]-1H-purin-6-one; HG1382; MFCD01630998; AKOS027328060; AS-49390; 5'-O-(4,4'-Dimethoxytrityl)-2'-O-methylinosine; A927015; J-700119; 5??-O-(4,4-Dimethoxytrityl)-2??-O-methyl ? inosine; 9- ( (2R, 3R, 4R, 5R)-5- ( (bis (4-methoxyphenyl) (phenyl)methoxy)methyl)-4-hydroxy-3-methoxytetrahydrofuran-2-yl)-1H-purin-6 (9H)-one; 9-[ (2R, 3R, 4R, 5R)-5-{[bis (4-methoxyphenyl) (phenyl)methoxy]methyl}-4-hydroxy-3-methoxyoxolan-2-yl]-9H-purin-6-ol. Grades: ≥ 97%. CAS No. 128219-84-1. Molecular formula: C32H32N4O7. Mole weight: 584.63.
5'-O-(Dimethoxytrityl)-5-(1-propynyl)-2'-deoxyuridine is an indispensable compound within the biomedical domain, serving as a foundational constituent in the research and development of antiviral medications like Brivudine. Synonyms: 2'-Deoxy-5'-O-[(2,3-dimethoxyphenyl)(diphenyl)methyl]-5-prop-1-yn-1-yluridine; 644962-74-3; 1-[(2R,4S,5R)-5-[[(2,3-dimethoxyphenyl)-diphenylmethoxy]methyl]-4-hydroxyoxolan-2-yl]-5-prop-1-ynylpyrimidine-2,4-dione; DTXSID50722442. Grades: ≥ 95%. CAS No. 644962-74-3. Molecular formula: C33H32N2O7. Mole weight: 568.62.
5'-O-(Dimethoxytrityl)-5-(1-propynyl)-2'-O-methyluridine is a crucial compound used for the research and development of nucleic acid analogs. With its unique chemical structure, it finds application as a building block for modified oligonucleotides. This compound has various potential uses, including the research of viral diseases, cancer and genetic disorders. Its versatile nature makes it an essential tool in drug discovery and the development of targeted therapies. Grades: ≥ 95%. CAS No. 644962-77-6. Molecular formula: C34H34N2O8. Mole weight: 598.65.
5'-O-(Dimethoxytrityl)-5,6-dihydro-2'-deoxyuridine is a vital compound acting as a precursor in the research and development of antiviral and antitumor drugs, specifically targeting DNA polymerases and nucleoside reverse transcriptase enzymes related to viral replication. Synonyms: 2'-DEOXY-5'-O-(DIMETHOXYTRITYL)-5,6-DIHYDROURIDINE; 869355-28-2. Grades: ≥ 97%. CAS No. 869355-28-2. Molecular formula: C30H30N2O7. Mole weight: 530.57.
5'-O-(Dimethoxytrityl)-5-fluoro-2'-O-methyluridine is a remarkable nucleoside derivative (C40H44FN3O8) extensively employed in the biomedical sector for synthesizing nucleotide prodrugs and RNA molecules. Renowned for its distinct structural modifications, this compound showcases promising antiviral capabilities against specific viral infections, predominantly RNA viruses. Synonyms: 5'-O-(DIMETHOXYTRITYL)-5-FLUORO-2'-O-METHYLURIDINE; 5'-O-(DMT)-5-FLUORO-2'-O-METHYLURIDINE. Grades: 95%. CAS No. 869355-45-3. Molecular formula: C31H31FN2O8. Mole weight: 578.59.
5'-O-(Dimethoxytrityl)-5-methyl-2'-O-methyluridine, a frequently used nucleoside building block in the synthesis of RNA oligomers, finds its application in the biomedical sector for creating RNA constructs that aid in the diagnosis and treatment of diseases like cancer and genetic disorders. Maintaining its purity and consistency is critical for precise and dependable RNA-based experiment results. Synonyms: 1-[(2R,3R,4R,5R)-5-[[(2,3-Dimethoxyphenyl)-diphenylmethoxy]methyl]-4-hydroxy-3-methoxyoxolan-2-yl]-5-methylpyrimidine-2,4-dione; Thymidine,5'-O-[bis(4-methoxyphenyl)phenylmethyl]-a-methoxy-. Grades: 95%. CAS No. 115173-73-4. Molecular formula: C32H34N2O8. Mole weight: 574.63.
The 5'-O-(Dimethoxytrityl)-5-[N-(6-(trifluoroacetamido)hexyl)-3-(E)-acrylamido]-2'-deoxyuridine represents a pivotal compound utilized in the field of biomedicine due to its indispensable role in the synthesis and advancement of potential antiviral agents. By specifically targeting viral replication processes and crucial enzymes, this product exhibits considerable promise in the treatment of a diverse range of viral infections. Thus, it assumes a vital role in the progression of pharmaceutical research, offering prospective solutions for tackling various viral diseases with utmost efficacy. Synonyms: 5'-DMT-5-TFA-aha-2'-deoxyuridine; 5'-DMT-5-TFA-aha-dU; 5'-O-DMT-5-[N-(6-(trifluoroacetamido)hexyl)-3-E-acryamido]-2'-deoxyuridine; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-5-[3-oxo-3-[[6-[(2,2,2-trifluoroacetyl)amino]hexyl]amino]-1-propen-1-yl]-Uridine; 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-2'-deoxy-5-[(1E)-3-oxo-3-({6-[(trifluoroacetyl)amino]hexyl}amino)-1-propen-1-yl]uridine. Grades: ≥98% by HPLC. CAS No. 252337-59-0. Molecular formula: C41H45F3N4O9. Mole weight: 794.84.
5'-O-(Dimethoxytrityl)-8-Oxo-N2-isobutyryl-2'-deoxyguanosine is an intricately designed and highly innovative derivative of 2'-deoxyguanosine, showcasing exceptional effectiveness in eradicating drug-resistant strains, rendering it an esteemed contender in the battle against notorious viral afflictions and malignant neoplasms. Grades: ≥ 97%. CAS No. 136859-77-3. Molecular formula: C35H37N5O8. Mole weight: 655.71.
5'-O-(Dimethoxytrityl)-N2-(dimethylaminomethylidene)-3'-deoxyguanosine is a highly intricate compound, exhibiting immense promise in the realm of antiviral drug discovery for the targeted research of ailments such as cytomegalovirus, herpes and Epstein-Barr virus. Furthermore, its utilization extends to the research and development of nucleoside analogs. Grades: ≥ 97%. CAS No. 172361-60-3. Molecular formula: C34H36N6O6. Mole weight: 624.69.
5'-O-(Dimethoxytrityl)-N2-methyl-2'-deoxy-guanosine is an indispensable compound, emerging as a pivotal compound for the research and development of deoxyribonucleic acid (DNA) moieties. Its intrinsic value resides in the research of pharmaceuticals, specifically in the sphere of antiviral therapeutics and remedies aimed at combatting afflictions pertaining to DNA. Synonyms: 2'-Deoxy-5'-O-[(2,3-dimethoxyphenyl)(diphenyl)methyl]-N-methylguanosine. CAS No. 869354-96-1. Molecular formula: C32H33N5O6. Mole weight: 583.64.
5'-O-Dimethoxytrityl-N2-(trifluoroacetamido)hexyl-2'-deoxyguanosine, a nucleoside analog, finds extensive application in the biomedical research and drug development as it is widely used for the synthesis of oligonucleotides. Thanks to its unique abilities to trigger cell death and hinder DNA replication, it has garnered significant attention for its suitability in treating cancer and viral infections. Intriguingly, recent findings suggest it may prove efficacious in targeting malignant cells exclusively, while safeguarding healthy cells against damage, thus holding immense promise as a cancer treatment of the future. Grades: ≥ 95%. Molecular formula: C39H43F3N6O7. Mole weight: 764.80.
5-O-(Dimethoxytrityl)-N4-dimethylaminomethylidene-5-iodo-2'-deoxycytidine is a highly potent and scientifically advanced antiviral medication renowned for its unparalleled effectiveness in research of a diverse array of viral infections, such as herpes viruses (including herpes simplex virus), hepatitis B and hepatitis C. This remarkable compound operates by skillfully obstructing the enhancement of viral DNA. Synonyms: 2'-Deoxy-5'-O-[(2,3-dimethoxyphenyl)(diphenyl)methyl]-N-[(dimethylamino)methylidene]-5-iodocytidine; 2'-Deoxy-5'-O-[(2,3-dimethoxyphenyl)(diphenyl)methyl]-N-[(dimethylamino)methylidene]-5-iodocytidine. CAS No. 717876-96-5. Molecular formula: C33H35IN4O6. Mole weight: 710.56.
5'-O-Dimethoxytrityl-N6-(N,N-dimethylaminomethylene)-8-aza-7-deaza-2'-deoxyadenosine is a critical compound commonly employed in the research and preparation of nucleoside analogs and other modified nucleotides. Due to its unique structure, it has shown promise in the research of certain viral infections and cancer. Grades: ≥ 97%. CAS No. 869355-14-6. Molecular formula: C34H36N6O5. Mole weight: 608.69.
5'-O-(Dimethoxytrityl)-N-(dimethylamino)methylidene-2'-deoxypseudoisocytidine is a remarkable compound renowned in the biomedical industry, serving as a pivotal ingredient in the formulation of antiviral medications and gene therapy strategies. Grades: ≥ 97%. CAS No. 307314-30-3. Molecular formula: C33H36N4O6. Mole weight: 584.69.
5'-O-(Dimethoxytrityl)-O6-phenyl-2'-deoxyinosine
5'-O-(Dimethoxytrityl)-O6-phenyl-2'-deoxyinosine is a paramount compound employed in the field of compound for the exploration of pharmaceutical entities. Its intricate molecular configuration renders it an indispensable protagonist in the pharmaceutical continuum, with a proficiency to target distinct cellular conduits responsible for the manifestation of ailments encompassing neoplastic maladies, viral pathogens and hereditary anomalies. Grades: ≥ 97%. CAS No. 133471-08-6. Molecular formula: C37H34N4O6. Mole weight: 630.71.
5'-O-DMT-2'-O-(2-methoxyethyl)-5-methyluridine
5'-O-DMT-2'-O-(2-methoxyethyl)-5-methyluridine is a potent compound used in research of RNA viruses, particularly hepatitis C virus and picornaviruses. This nucleoside analogue inhibits viral replication by interfering with viral RNA research and development. Synonyms: 5'-O-(4,4'-Dimethoxytrityl)-2'-O-(2-methoxyethyl)-5-methyluridine; 5'-O-DMT-2'-O-MOE-5-methyluridine; 1- ( (2R, 3R, 4R, 5R)-5- ( (bis (4-methoxyphenyl) (phenyl)methoxy)methyl)-4-hydroxy-3- (2-methoxyethoxy)tetrahydrofuran-2-yl)-5-methylpyrimidine-2, 4 (1H, 3H)-dione; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-5-methyluridine. Grades: ≥98% by HPLC. CAS No. 163759-50-0. Molecular formula: C34H38N2O9. Mole weight: 618.67.
5'-O-DMT-2'-O-methylcytidine
5'-O-DMT-2'-O-methylcytidine is a biomedicine research product used for the treatment of viral infections, cancer, and neurological disorders. It acts as an antiviral and anticancer agent by inhibiting viral replication and tumor growth, respectively. Additionally, it also has neuroprotective properties that help in treating neurological disorders. Synonyms: 5'-O-DMT-2'-O-methyl-D-cytidine; 5'-O-DMT-2'-OMe-rC; 5'-O-(4,4'-Dimethoxytrityl)-2'-O-Methyl-cytidine; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-O-methylcytidine. Grades: ≥98% by HPLC. CAS No. 103285-21-8. Molecular formula: C31H33N3O7. Mole weight: 559.62.
5'-O-DMT-2'-O-methylguanosine
5'-O-DMT-2'-O-methylguanosine, a nucleoside analogue, finds its purpose in biomedical research due to its potential antiviral activity against RNA viruses, an area of significant scientific interest. Its inhibitory role in the replication of notorious viruses such as Zika virus and hepatitis C virus warrants further academic study. Synonyms: 2'-O-Methyl-5'-O-DMT-D-guanosine; 5'-O-Dimethoxytrityl-2'-O-methylguanosine; 5'-O-DMT-2'-O-methyl-D-guanosine. Grades: ≥ 98% (HPLC). CAS No. 103285-24-1. Molecular formula: C32H33N5O7. Mole weight: 599.65.
5'-O-DMT-2'-O-methylinosine 3'-CE phosphoramidite
5'-O-DMT-2'-O-methylinosine 3'-CE phosphoramidite is a vital component used in the research and development of RNA molecules for biomedical research. It functions as a phosphoramidite building block to introduce the modified nucleoside 5'-O-DMT-2'-O-methylinosine into RNA sequences. This modified nucleoside plays a crucial role in studying the structure, function and therapeutic potential of RNA molecules involved in various diseases, including cancer and genetic disorders. Synonyms: 2/'-O-METHYL-I CEP; 2'-O-METHYL-5'-O-DMT-INOSINE-3'-CE-PHOSPHORAMIDITE; 3-[[ (2R, 3R, 4R, 5R) -2-[[Bis (4-methoxyphenyl) -phenylmethoxy]methyl]-4-methoxy-5- (6-oxo-1H-purin-9-yl) oxolan-3-yl]oxy-[di (propan-2-yl) amino]phosphanyl]oxypropanenitrile; 2'-O-Methyl Inosine Phosphoramidite; 5'-O-(4,4-Dimethoxytrityl)-2'-O-methyl inosine-3'-CED phosphoramidite; 5'-O-(4,4'-Dimethoxytrityl)-2'-O-methyl-inosine-3'-cyanoethyl phosphoramidite; Inosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-methyl-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]. Grades: ≥ 98%. CAS No. 128219-85-2. Molecular formula: C41H49N6O8P. Mole weight: 784.83.
5'-O-DMT-2'-O-methyl-N6-phenoxyacetyladenosine 3'-CE phosphoramidite is a promising molecular implement utilized in the synthesis of modified oligonucleotides that can be used in various applications including RNA interference and antisense therapy for treating multifarious diseases like viral infections, genetic disorders, and cancer. With the potential to revolutionize the field of medicine, this molecular tool boasts unparalleled effectiveness in terms of successfully delivering modified oligonucleotides to their targets with precision. Synonyms: 2'-OMe-Pac-A phosphoramidite; 5'-O-DMT-2'-O-methyl-N6-phenoxyacetyl-D-adenosine 3'-CE phosphoramidite. Grades: 97%. Molecular formula: C49H56N7O9P. Mole weight: 918.01.
5'-O-DMT-2'-O-propylphthalimidouridine
5'-O-DMT-2'-O-propylphthalimidouridine, a modified nucleoside, serves as a pivotal building block for the synthesis of numerous nucleic acid analogs. Its wide-ranging applications span from oligonucleotide development to the investigation of nucleic acid structure. Moreover, it holds promise in combating illnesses like cancer and viral infections. Synonyms: 5'-O-DMT-2'-O-propylphthalimido-D-uridine. Molecular formula: C41H39N3O10. Mole weight: 733.78.
5'-O-DMT-2'-O-triisopropylsilyloxymethyl-N2-methylguanosine 3'-CE phosphoramidite is a complex chemical compound that is frequently applied within the biomedical industry. It acts as a fundamental intermediate component for the production of RNA oligonucleotides, a vital tool utilized in gene manipulation and the treatment of genetic illnesses. This innovative compound is highly essential in the development of RNA-based therapeutics for precise cancer treatment and targeted treatment of viral infections. Synonyms: 5'-O-DMT-2'-O-TOM-N2-methylguanosine 3'-CE phosphoramidite. Molecular formula: C51H72N7O9PSi. Mole weight: 986.22.
5'-O-DMT-4-methoxythymidine 3'-CE phosphoramidite
5'-O-DMT-4-methoxythymidine 3'-CE phosphoramidite is a chemical reagent used in solid phase DNA synthesis. It serves as a key component in the automated synthesis of nucleic acid polymers for research, diagnostics, and therapeutics. This phosphoramidite is particularly useful for introducing a 4-methoxythymidine base into DNA sequences, which can have implications in gene regulation and anticancer drug development. Synonyms: 5'-O-DMT-O4-methylthymidine 3'-CE phosphoramidite; 5'-O-DMT-4-methoxy-D-thymidine 3'-CE phosphoramidite. Molecular formula: C41H51N4O8P. Mole weight: 758.86.
5'-O-DMT-5-Ethynyl-2'-deoxyuridine 3'-CE phosphoramidite is a crucial tool in the research and development of modified oligonucleotides. It facilitates the incorporation of the 5'-O-DMT-5-Ethynyl-2'-deoxyuridine nucleotide into the desired sequence during solid-phase research and development. This phosphoramidite derivative finds applications in drug discovery, therapeutics and molecular biology, aiding in the research of nucleic acid analogs for various diseases. Synonyms: N-Benzoyl-5-((2-cyanoethoxy)methyl)-2'-deoxycytidine CEP; Cytidine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-5-[(2-cyanoethoxy)methyl]-2'-deoxy-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; N-Benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-5-[(2-cyanoethoxy)methyl]-2'-deoxy-3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]cytidine. Grades: ≥95% by HPLC. CAS No. 188411-06-5. Molecular formula: C50H57N6O9P. Mole weight: 917.00.
5'-O-DMT-adenosine
It is used for nucleoside modification. Synonyms: 5'-O-DMT adenosine; 5'-O-(4,4'-Dimethoxytrityl)adenosine; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-adenosine; (2R, 3R, 4S, 5R) -2- (6-amino-9H-purin-9-yl) -5- ( (bis (4-methoxyphenyl) (phenyl) methoxy) methyl) tetrahydrofuran-3, 4-diol; 5-O-Dimethoxytrityladenosine. Grades: ≥95% by HPLC. CAS No. 81352-25-2. Molecular formula: C31H31N5O6. Mole weight: 569.61.
5'-O-DMT-cytidine
5'-O-DMT-cytidine is a highly influential and extensively utilized component, having extraordinary aptitude as a remarkable countermeasure against both DNA and RNA viral compounds. Profoundly indispensable in the confrontment of pernicious viral afflictions, such as herpes simplex, HIV and hepatitis, this exalted compound exhibits an unparalleled capability in suppressing viral replication. Synonyms: 5'-O-(4,4'-Dimethoxytrityl)cytidine; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]cytidine; 4-Amino-1- ( (2R, 3R, 4S, 5R)-5- ( (bis (4-methoxyphenyl) (phenyl)methoxy)methyl)-3, 4-dihydroxytetrahydrofuran-2-yl)pyrimidin-2 (1H)-one; DMT-Cr. Grades: ≥95%. CAS No. 112897-99-1. Molecular formula: C30H31N3O7. Mole weight: 545.58.
5'-O-DMT-N2-isobutyryl-2'-deoxyguanosine 3'-CE phosphoramidite is a pivotal compound employed in oligonucleotide research within the biomedical sector, emerging as an instrumental factor for nucleic acid modification, labeling and analysis. Synonyms: dG(iBu) CEP; 5'-Dimethoxytrityl-N-isobutyryl-2'-deoxyGuanosine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite. Grades: ≥ 98%. CAS No. 93183-15-4. Molecular formula: C44H54N7O8P. Mole weight: 839.92.
5'-O-DMT-N2-isobutyryl-2'-O-propargylguanosine
5'-O-DMT-N2-isobutyryl-2'-O-propargylguanosine is an advanced compound prescribed for research of viral infections, demonstrating inhibitory efficacy by selectively targeting specific RNA viruses. Employing a potent mechanism of inhibiting viral replication and considerably attenuating viral loads, this compound exhibits promising potential in the research of RNA virus-induced ailments such as influenza and hepatitis C. Synonyms: N2-iso-Butyroyl-5'-(4,4'-dimethoxytrityl)-2'-O-propargylguanosine; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-N-(2-methyl-1-oxopropyl)-2'-O-2-propyn-1-yl-Guanosine; 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-N-isobutyryl-2'-O-2-propyn-1-ylguanosine. Grades: ≥95%. CAS No. 171486-53-6. Molecular formula: C38H39N5O8. Mole weight: 693.74.
5'-O-DMT-N2-phenylacetylguanosine
5'-O-DMT-N2-phenylacetylguanosine is a highly intricate and biologically potent entity, serving as a pivotal foundation in the research of afflictions plaguing the realm of neurology, viral pathology and select carcinomas. Synonyms: 5'-O-DMT-N2-phenylacetyl-D-guanosine. CAS No. 172965-92-3. Molecular formula: C39H37N5O8. Mole weight: 703.76.
5'-O-DMT-N4-Isobutyryl-2'-deoxycytidine-3'-CE Phosphoramidite, a chemical reagent widely employed in oligonucleotide synthesis for biomedical research, manifests remarkable versatility in targeting a wide range of ailments, spanning from cancer to genetic disorders. With its ready availability and proven efficacy in in-vitro experiments, this chemical reagent is the go-to choice for generating novel and effective therapeutic oligonucleotides. Synonyms: IBU-DC Phosphoramidite; 5'-O-[Bis (4-methoxyphenyl) (phenyl)methyl]-3'-O-[ (2-cyanoethoxy) (diisopropylamino)phosphino]-2'-deoxy-N-isobutyrylcytidine; 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-{(2-cyanoethoxy)[di(propan-2-yl)amino]phosphanyl}-2'-deoxy-N-(2-methylpropanoyl)cytidine; N-Isobutyryl-3'-O-[ (2-cyanoethoxy) (diisopropylamino)phosphino]-5'-O- (4, 4'-dimethoxytrityl)-2'-deoxycytidine; IBU-dC CEP. Grades: ≥98% by HPLC. CAS No. 110522-84-4. Molecular formula: C43H54N5O8P. Mole weight: 799.90.
5'-O-DMT-N6-methyl-2'-deoxyadenosine 3'-CE phosphoramidite is a pivotal entity harnessed within the realm of biomedical industry, manifesting its indispensability within nucleic acid research and development. Synonyms: 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-N-methyl-Adenosine 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]; 2'-Deoxy-5'-O-DMT-N6-methyladenosine 3'-CE phosphoramidite; N6-Methyl-dA phosphoramidite. Grades: ≥98% by HPLC. CAS No. 105931-58-6. Molecular formula: C41H50N7O6P. Mole weight: 767.85.
5'-O-DMTr-2',2'-difluoro-dC(Bz)-methylphosphonamidite is an indispensable entity employed in the biomedical sector for the purpose of constructing nucleic acids. Its function revolves around acting as an adjusted constituent that brings about the introduction of the 2',2'-difluoro modification at the 2'-position of a deoxycytidine (dC) nucleoside. This particular alteration augments the propensity for nucleic acids to bind and endure, thereby bestowing remarkable utility in the realms of pharmaceutical exploration, genetic repression and the elucidation of pathologies on a molecular scale. Grades: ≥95%. Molecular formula: C44H49F2N4O7P. Mole weight: 814.85.
5'-O-DMTr-2'-FU-methylphosphonamidite
5'-O-DMTr-2'-FU-methylphosphonamidite is a vital component in the development of modified nucleosides used in the development of antiviral drugs. It plays a crucial role in the research of viral infections such as hepatitis C and HIV. This compound enables the efficient incorporation of modified nucleotides during the research and development of oligonucleotides. Synonyms: 5'-O-DMTr-2'-deoxy-2'-fluorouridine-3'-O-(P-methyl-N,N-diisopropylamino)phosphonamidite. Grades: ≥95%. Molecular formula: C37H45FN3O7P. Mole weight: 693.74.
5'-O-DMTr-2'-OMeU-methylphosphonamidite
5'-O-DMTr-2'-OMeU-methylphosphonamidite is an indispensable recompound widely employed in the field of compound, exhibiting immense significance in the research and development of altered oligonucleotides meticulously crafted for gene therapy and medicinal chemistry. Moreover, it assumes a pivotal role in the research and development of antisense oligonucleotides explicitly engineered to combat genetic disorders, infectious ailments and select malignancies. Synonyms: Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-methyl-, 3'-[P-methyl-N,N-bis(1-methylethyl)phosphonamidite]; 5'-O-DMTr-2'-O-methyluridine-3'-O-(P-methyl-N,N-diisopropylamino)phosphonamidite. Grades: ≥95%. CAS No. 191786-64-8. Molecular formula: C38H48N3O8P. Mole weight: 705.78.
5'-O-DMTr-3'-deoxyuridine
5'-O-DMTr-3'-deoxyuridine, a highly versatile compound extensively utilized in the field of biomedicine, serves as an indispensable entity in DNA synthesis and pharmaceutical investigations. Remarkably, this compound exhibits its prowess by acting as a transformative moiety, facilitating the integration of an array of functional groups into therapeutic agents. Grades: ≥95%. Molecular formula: C30H30N2O7. Mole weight: 530.57.
5'-O-DMTr-3'-deoxyuridine 2'-CED phosphoramidite
5'-O-DMTr-3'-deoxyuridine 2'-CED phosphoramidite is a vital compound extensively utilized in the field of biomedicine. This product acts as a key reagent in the synthesis of modified nucleotides for research purposes. It is commonly employed in DNA and RNA synthesis, particularly in the development of oligonucleotides for therapeutic interventions targeting various diseases, such as cancer and viral infections. Grades: ≥95%. CAS No. 161503-98-6. Molecular formula: C39H47N4O8P. Mole weight: 730.79.
5'-O-DMTr-N6-ethyl-2'-deoxyadenosine
5'-O-DMTr-N6-ethyl-2'-deoxyadenosine, an essential element in biomedicine, holds immense potential in combating multiple ailments. Its remarkable ability to target drug-resistant cancers, such as leukemia and solid tumors, has gained significant recognition. By impeding crucial enzymes responsible for cancer cell proliferation, it emerges as a promising contender for tailored therapeutic interventions. Grades: ≥95%. Molecular formula: C33H35N5O5. Mole weight: 581.66.
5'-O-DMT-thymidine-3'-O-succinic acid
5'-O-DMT-thymidine-3'-O-succinic acid, an indispensable compound extensively employed in the biomedical sector for versatile applications, exhibits its profound significance. Functioning as a pivotal precursor in antiviral drug synthesis, it selectively combats RNA and DNA viruses. Additionally, it remarkably contributes to the advancement of pharmaceuticals dedicated to the treatment of HIV, hepatitis, and cancer. Synonyms: 5'-O-(4,4'-Dimethoxytrityl)-thymidine-3'-O-succinic acid; 5'-O-(p,p'-Dimethoxytrityl)thymidine 3'-(hydrogen succinate). Grades: ≥ 99% (HPLC). CAS No. 74405-40-6. Molecular formula: C35H36N2O10. Mole weight: 644.67.
5-OH-dU-CE Phosphoramidite
5-OH-dU-CE Phosphoramidite is an indispensable recompound within the realm of compound assuming a pivotal function in the research and development of altered nucleosides, thereby facilitating DNA/RNA investigations. It holds particular significance in the formulation of oligonucleotides, intended for diagnostics and therapeutics relating to hereditary afflictions or viral infestations. Synonyms: 5'-Dimethoxytrityl-5-O-Acetyl-2'-deoxyUridine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite. Grades: 95%. CAS No. 197229-19-9. Molecular formula: C41H49N4O10P. Mole weight: 788.83.
5'-OMe-dT-CE Phosphoramidite
5'-OMe-dT-CE Phosphoramidite is a pivotal component in the research and development of customized oligonucleotides. Renowned for its unparalleled resilience and remarkable integration efficiency, 5'-OMe-dT-CE Phosphoramidite finds extensive utilization in the development of antiviral medication and gene therapeutics. Synonyms: 5'-O-methyl-2'-deoxyThymidine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; 5'-OMe-dT-CEP. Grades: 95%. CAS No. 149681-62-9. Molecular formula: C20H33N4O6P. Mole weight: 456.48.
5'-O-Methoxytrityluridine 3'-CE phosphoramidite
5'-O-Methoxytrityluridine 3'-CE phosphoramidite is an exceedingly intricate chemical, often employed in the creation of synthetic DNA and RNA. It plays a critical role in oligonucleotide fusion techniques, protecting the sensitive nucleotide bonds during synthesis. The proficiency exhibited by this product extends to cancer diagnoses, particularly in cases of colorectal and lung cancer, via the employment of diagnostic assays. Synonyms: 5'-O-Methoxytrityl-D-uridine 3'-CE phosphoramidite. Molecular formula: C39H47N4O8P. Mole weight: 730.81.
5'-O-Methylthymidine
5'-O-Methylthymidine is a vital component used in the biomedical industry for the research and development of antiviral drugs like Acyclovir and Ganciclovir. It plays a crucial role in studying viral infections caused by herpes simplex virus (HSV) and cytomegalovirus (CMV) as well as preventing their replication. Synonyms: 5'-O-Methyl-D-thymidine; 1-[(2R,4S,5R)-4-hydroxy-5-(methoxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione; 5A'A inverted exclamation markA'A-O-Methyl-D-thymidine; Thymidine,5'-O-methyl. Grades: ≥ 95%. CAS No. 14504-60-0. Molecular formula: C11H16N2O5. Mole weight: 256.26.
5'-O-p-Anisoyl-2'-deoxyuridine 3'-CE phosphoramidite - a pivotal component in oligonucleotide synthesis, essential for developing treatments against viral infections and cancer. Through its potent ability to hinder RNA and DNA virus replication and selectively restrain tumor cells, this product has become a fundamental instrument in biomedical research, promoting the creation of novel therapeutic drugs against critical illnesses. Molecular formula: C26H35N4O8P. Mole weight: 562.55.
5'-O-p-Anisoyl-2'-O-tert-butyldimethylsilyluridine 3'-CE phosphoramidite is a phosphoramidite recompound used as an indispensable tool for DNA research and development. Its significance lies in facilitating the compoundion of oligonucleotides, thereby assuming a pivotal role in fostering the development of nucleic acid-based therapeutics and diagnostics. Molecular formula: C32H49N4O9PSi. Mole weight: 692.83.
5'-O-p-Anisoyl-3'-azido-3'-deoxythymidine
5'-O-p-Anisoyl-3'-azido-3'-deoxythymidine, an antiviral drug used for the treatment of HIV infection, operates by impeding the reverse transcriptase enzyme obligatory for viral replication. Intriguingly, this compound has also been probed for its budding usefulness in cancer treatment. It has come to light that this antiviral drug holds great potential in the treatment of cancer due to its distinctive attributes in mitigating the enzymes involved in the propagation of cancer cells. Synonyms: 5'-O-p-Anisoyl-3'-azido-3'-deoxy-D-thymidine. Molecular formula: C18H19N5O6. Mole weight: 401.37.
5'-O-p-Anisoyl-N6-benzoyl-2'-deoxyadenosine
5'-O-p-Anisoyl-N6-benzoyl-2'-deoxyadenosine, a potent antineoplastic agent, has emerged as a viable treatment option for various malignancies. Its robust tumor-suppressing mechanisms include disruption of cell proliferation and activation of programmed cell death pathways within malignant cells, illustrating promising prospects for future oncological therapies. Molecular formula: C25H23N5O6. Mole weight: 489.48.
5'-O-p-Anisoyl-N6-benzoyl-2'-O-tert-butyldimethylsilyladenosine 3'-CE phosphoramidite, a versatile chemical reagent, finds wide application in the field of molecular biology. Its utility lies in the synthesis of oligonucleotides by enhancing the stability of modified DNA sequences and RNAs. Researchers rely on this reagent to unravel complex biological phenomena and their underlying mechanisms. Synonyms: 5'-O-p-Anisoyl-N4-benzoyl-2'-O-tert-butyldimethylsilyl-D-adenosine 3'-CE phosphoramidite. Molecular formula: C40H54N7O8PSi. Mole weight: 819.98.
5'-O-p-Anisoylthymidine 3'-CE phosphoramidite
5'-O-p-Anisoylthymidine 3'-CE phosphoramidite is an indispensable reagent in the world of biomedicine, utilized extensively in the synthesis of DNA and RNA oligonucleotides. Its molecular makeup grants a myriad of research opportunities in the realm of disease research, from the minute intricacies of genetic disorders to the rampant growth of malignant cancers and treacherous viral infections. With its impeccable efficiency in integrating itself into nucleic acid chains, this reagent proves itself as a pivotal tool in drug development, guiding humanity towards a brighter, healthier future. Molecular formula: C27H37N4O8P. Mole weight: 576.58.
5'-O-(p-Toluenesulfonyl)-2'-deoxyuridine
5'-O-(p-Toluenesulfonyl)-2'-deoxyuridine, can be used as antimalarials using QSAR, pharmacophore mapping and multiple docking studies in biological study of exploring structural requirements for class of nucleoside inhibitors. Synonyms: 1-(5-O-Tosyl-2-deoxy-β-D-erythro-pentofuranosyl)uracil; 2'-Deoxy-5'-O-p-toluenesulfonyluridine; 5'-O-Tosyl-2'-deoxyuridine; 5'-O-p-Tolylsulfonyl-2'-deoxyuridine. Grades: 95%. CAS No. 27999-47-9. Molecular formula: C16H18N2O7S. Mole weight: 382.39.
5'-O-TBDPS-5-methyl-2,2'-anhydrouridine
5'-O-TBDPS-5-methyl-2,2'-anhydrouridine is a profoundly influential entity in the realm of compound, manifesting its exceptional antiviral potential, specifically against the scourge of RNA viruses like SARS-CoV-2 and influenza. Synonyms: (2R,4R,5R,6S)-4-[[tert-butyl(diphenyl)silyl]oxymethyl]-5-hydroxy-11-methyl-3,7-dioxa-1,9-diazatricyclo[6.4.0.02,6]dodeca-8,11-dien-10-one. Grades: ≥95%. CAS No. 171763-19-2. Molecular formula: C26H30N2O5Si. Mole weight: 478.61.
5'-O-(t-Butyldimethylsilyl)thymidine
5'-O-(t-Butyldimethylsilyl)thymidine is a modified form of thymidine used in the biomedical industry. It is commonly employed in the synthesis of nucleic acid analogs and oligonucleotides for research purposes. Its t-butyldimethylsilyl group protects the thymidine molecule during the chemical reactions. It finding application in drug discovery, especially for developing antiviral and anticancer drugs. Synonyms: 5'-tert-butyldimethylsilyloxy-2'-deoxythymidine; 5'-O-TBDMS-thymidine; 5'-O-(t-Butyldimethylsilyl)thymidine; 1-((2R,4S,5R)-5-(((tert-butyldimethylsilyl)oxy)methyl)-4-hydroxytetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione; 5-Methyl-5'-O-(tert-butyldimethylsilyl)-2'-deoxyuridine. Grades: ≥97% by HPLC. CAS No. 40733-28-6. Molecular formula: C16H28N2O5Si. Mole weight: 356.49.
5'-O-tert-Butyldimethylsilylthymidine 3'-CE phosphoramidite is a critical intermediate for the synthesis of oligonucleotides, often used in the research of DNA-based therapeutics and diagnosis of genetic diseases. Its high yield, purity, and stability ensure efficient oligonucleotide synthesis for various applications, including gene therapy, RNA interference, and molecular diagnostics. Molecular formula: C25H45N4O6PSi. Mole weight: 556.72.
5'-O-tert-Butyldimethylsilyluridine
5'-O-tert-Butyldimethylsilyluridine, a prodrug of uridine, with its demonstrated efficacy in treating various cancers such as leukemia and myeloma, has emerged as an avant-garde therapeutic agent. This bioactive compound accelerates the cytotoxic effect of chemotherapeutic agents like gemcitabine, reinforcing its position as a promising addition to combination therapies for cancer treatment. With optimal solubility and stability characteristics, this drug acquaints easier administration and brings about increased efficacy in vivo, leading to better clinical outcomes. Synonyms: 5'-O-TBDMS-uridine. CAS No. 54925-65-4. Molecular formula: C15H26N2O6Si. Mole weight: 358.46.
5'-O-tert-Butylmethylsilyl-2'-deoxy-5-iodocytidine is a formidable compound, exhibiting remarkable efficacy in research of an array of ailments induced by viral adversaries. Through its potent mechanism of selectively restraining viral replication, it emerges as an impactful antiviral warrior. Synonyms: 5'-tert-butyldimethylsilyloxy-5-iodo-2'-deoxycytidine; 5'-O-TBDMS-5-iodo-2'-deoxycytidine; 2'-Deoxy-5'-O-[(1,1-dimethylethyl)dimethylsilyl]-5-iodo-Cytidine; 4-Amino-1-((2R,4S,5R)-5-(((tert-butyldimethylsilyl)oxy)methyl)-4-hydroxytetrahydrofuran-2-yl)-5-iodopyrimidin-2(1H)-one; 5-TBDMS-5-I-2-dC. Grades: ≥97% by HPLC. CAS No. 666848-11-9. Molecular formula: C15H26IN3O4Si. Mole weight: 467.38.
5'-O-Trityl-2',3'-dehydrothymidine
5'-O-Trityl-2',3'-dehydrothymidine, a pharmaceutical compound utilized in the treatment of viral infections, exerts its effect through its capacity to thwart the replication of viral DNA. This unique substance has demonstrated robust potential as a building block in the development of therapeutic interventions targeting notoriously challenging viruses such as hepatitis B and C. Synonyms: 5-Methyl-1-(5-trityloxymethyl-2,5-dihydro-furan-2-yl)-1H-pyrimidine-2,4-dione. CAS No. 5964-41-0. Molecular formula: C29H26N2O4. Mole weight: 466.53.
5'-O-Tritylthymidine 3'-CE phosphoramidite
5'-O-Tritylthymidine 3'-CE phosphoramidite, a versatile and indispensable reagent wielded in oligonucleotide synthesis techniques, earns its stripes adding a 3'-phosphate group. Favored in academia for biomedicine research as well as the flourishing therapeutics industry, it has paved the way towards treating an array of ailments from genetic disorders to viral infections to cancer. CAS No. 198637-50-2. Molecular formula: C38H45N4O6P. Mole weight: 684.78.
5'-O-Trityl Uridine
5'-O-Trityl Uridine, a paramount compound extensively employed in the biomedical domain, demonstrates outstanding prowess in the orchestration of RNA molecule research and development. This remarkable entity assumes the vital responsibility of safeguarding uridine throughout chemical reactions, thus enabling the discriminatory alteration of alternative functional groups. Remarkably adaptable, this multifaceted compound showcases unbounded utility in advancing RNA-centric therapeutics and facilitating comprehensive investigations into the intricate intricacies of RNA's overarching structure and intrinsic functioning. Synonyms: 5'-Trt-dU; 5'-O-Trityluridine; 5'-O-Triphenylmethyluridine; NSC 97038; 5'-O-Trityl-D-uridine; 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-((trityloxy)methyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione. Grades: ≥98% by HPLC. CAS No. 6554-10-5. Molecular formula: C28H26N2O6. Mole weight: 486.52.
5'-O-Trityluridine-2',3'-lyxo-epoxide
As a synthetic intermediate, it can be used to synthesize a variety of antiviral agents. Uses: Synthetic intermediate used to synthesize a variety of antiviral agents. Synonyms: 1-[2,3-Anhydro-5-O-(triphenylmethyl)-β-D-lyxofuranosyl]-2,4(1H,3H)-pyrimidinedione. CAS No. 96253-10-0. Molecular formula: C28H24N2O5. Mole weight: 468.5.
5'-Oxo-8,5'-cycloadenosine
5'-Oxo-8,5'-cycloadenosine is a formidable adenosine receptor antagonist, finding profound utility within the biomedical realm for exploring the enigmatic nature of adenosine across diverse ailments. This multifaceted compound serves as a powerful investigative tool, used for studying the intricate web of physiological adenosine receptor functions that intertwine with maladies including inflammation, cardiovascular afflictions and neurodegenerative complexities. Synonyms: 5'-OXO-8,5'-CYCLOADENOSINE; 869355-06-6; (1R, 12S, 13S, 14R)-7-amino-13, 14-dihydroxy-15-oxa-2, 4, 6, 9-tetrazatetracyclo[10.2.1.02, 10.03, 8]pentadeca-3, 5, 7, 9-tetraen-11-one; (7S,8S,9R,10R)-4-Amino-8,9-dihydroxy-7,8,9,10-tetrahydro-6H-7,10-epoxyazepino[1,2-e]purin-6-one. Grades: ≥ 97%. CAS No. 869355-06-6. Molecular formula: C10H9N5O4. Mole weight: 263.21.
5-Propargylamino-2'-deoxycytidine-5'-Triphosphate
5-Propargylamino-2'-deoxycytidine-5'-Triphosphate, a nucleotide analogue, is a potent tool for investigating the intricate dynamics of RNA modification. During transcription, it seamlessly incorporates into RNA and proficiently impedes reverse transcriptase, conferring multifaceted advantages for antiviral therapy research. Its multiplicity lies in its capability to decode the mechanistic details underlying RNA structure and function for deciphering the dynamics of RNA-protein interactions, enabling rapid discoveries in the realm of biomedical sciences. Synonyms: 5-Propargylamino-dCTP; 5-Propargyl-dCTP. Grades: ≥90% by AX-HPLC. CAS No. 115899-39-3. Molecular formula: C12H19N4O13P3. Mole weight: 520.20.