BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| 5'-Deoxy-5'-N-methylaminothymidine hydrochloride | 5'-Deoxy-5'-N-methylaminothymidine hydrochloride is a potent antiviral compound exhibiting activity against herpes simplex virus and varicella-zoster virus in the research for related infections. This compound is also known as 5'-DMT, functions by inhibiting viral DNA enhancement. Synonyms: 5'-Deoxy-5'-(methylamino)thymidine hydrochloride; 1-((2R,4S,5R)-4-hydroxy-5-((methylamino)methyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione hydrochloride. Grades: ≥95%. Molecular formula: C11H18ClN3O4. Mole weight: 291.73. |  |
| 5'-Deoxy-5'-N,N-diethylaminothymidine | 5'-Deoxy-5'-N,N-diethylaminothymidine is an immensely powerful antiviral compound, standing at the forefront of the research of battling against notorious viral afflictions including HIV and herpes simplex virus (HSV). Its remarkable mechanism of hindering viral replication in affected cells, resulting in a mitigated dissemination and intensity of those infections. Grades: ≥95%. CAS No. 2305415-88-5. Molecular formula: C14H23N3O4. Mole weight: 297.35. | |
| 5'-Deoxy-5'-N,N-dimethylaminothymidine | 5'-Deoxy-5'-N,N-dimethylaminothymidine is an exceptionally powerful antiviral compound, finding its application in the research of a broad spectrum of viral ailments, encompassing influenza, herpes and hepatitis. Acting as a nucleoside analogue, this compound skillfully disrupts the enhancement of viral DNA, unequivocally restraining viral replication and alleviating the intensity of viral infections. Synonyms: 1-[(2R,4S,5R)-5-[(dimethylamino)methyl]-4-hydroxyoxolan-2-yl]-5-methylpyrimidine-2,4-dione; 5'-Deoxy-5'-(dimethylamino)thymidine. Grades: ≥95%. CAS No. 162466-79-7. Molecular formula: C12H19N3O4. Mole weight: 269.30. | |
| 5'-Deoxy-8,5'-cycloadenosine | 5'-Deoxy-8,5'-cycloadenosine, an intriguing nucleoside analog, demonstrates immense potential in the realm of biomedicine. With its profound antitumor effects, this compound emerges as a compelling contender for combating diverse cancer types. By virtue of its distinctive molecular architecture, 5'-Deoxy-8,5'-cycloadenosine showcases remarkable prowess in precisely targeting malignant cells and impeding their proliferation. Grades: ≥ 97%. CAS No. 3415-89-2. Molecular formula: C10H11N5O3. Mole weight: 249.23. | |
| 5'-Deoxy thymidine | 5'-Deoxy thymidine is readily imported by cellular nucleoside importers and competitively inhibits the influx of thymidine. It demonstrates antibacterial activity against B. subtilis and S. aureus. Synonyms: 5'-Deoxythymidine; Thymidine, 5'-deoxy-; 2',5'-Dideoxythymidine; 1-((2R,4S,5R)-4-hydroxy-5-methyltetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione; 5-Methyl-2',5'-dideoxyuridine; 2',5'-Dideoxy-5-methyluridine; 1-(2,5-Dideoxy-β-D-erythro-pentofuranosyl)-4-hydroxy-5-methyl-2(1H)-pyrimidinone. Grades: ≥95%. CAS No. 3458-14-8. Molecular formula: C10H14N2O4. Mole weight: 226.23. | |
| 5'-Deoxyuridine | 5'-Deoxyuridine is a uridine derivative used as a therapeutic agent for allergy, cancer, infection and autoimmune disease treatment. Synonyms: 5'-Deoxy-uridine; Uridine, 5'-deoxy-; 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-methyltetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione. Grades: ≥95%. CAS No. 15958-99-3. Molecular formula: C9H12N2O5. Mole weight: 228.20. | |
| 5'-Dimethoxytrityl-N-phenoxyacetyl-Adenosine, 2'-O-TBDMS-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite | 5'-Dimethoxytrityl-N-phenoxyacetyl-Adenosine is an immensely potent phosphoramidite, boasting significant utility in the research and development of oligonucleotides intended for diverse biomedical purposes. Notably, its employment expedites the incorporation of Phenoxyacetyl-Adenosine moieties into DNA molecules, thereby facilitating comprehensive examination of DNA-protein interactions while concurrently streamlining gene sequencing endeavors. Synonyms: PAC-rA CEP; N-blocked-5'-O-DMT-2'-O-TBDMS CED adenosine phosphoramidit. CAS No. 121058-86-4. Molecular formula: C54H68N7O9PSi. Mole weight: 1018.22. | |
| 5'-Dimethoxytrityl-N-p-isopropyl-phenoxyacetyl-2'-deoxyGuanosine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite | 5'-Dimethoxytrityl-N-p-isopropyl-phenoxyacetyl-2'-deoxyGuanosine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite is a component of great interest in the construction of oligomers involved in transcriptomics. Used notably in gene therapy, this product facilitates the gathering of crucial molecular information aimed at deciphering critical processes such as transcription regulation, gene silencing, and DNA replication. Additionally, with its established role in investigative efforts focused on bettering patient outcomes in a range of cancers and genetic disorders, the extensive utility of this reagent is abundantly clear. Synonyms: iPrPAC-dG CEP. CAS No. 150065-82-0. Molecular formula: C51H60N7O9P. Mole weight: 946.05. | |
| 5'-Dimethoxytrityl-N-p-isopropylphenoxyacetyl-Guanosine, 2'-O-TBDMS-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite | 5'-Dimethoxytrityl-N-p-isopropylphenoxyacetyl-Guanosine is a chemical compound extensively employed in the research and development of nucleotide analogues. It facilitates their integration into oligonucleotides to facilitate precise pharmaceutical conveyance and gene-based curative methodologies. Synonyms: iPrPAC-rG CEP. CAS No. 956580-73-7. Molecular formula: C57H74N7O9PSi. Mole weight: 1060.3. | |
| 5'-DMT-2,6-diamino-purine-riboside (N6-Soluble in DMF) (N2-iBu) | 5'-DMT-2,6-diamino-purine-riboside (N6-Soluble in DMF) (N2-iBu) is an exceedingly efficacious and exclusively targeted antagonistic compound boasting its inherent ability to effortlessly dissolve in DMF. Grades: ≥ 98% by HPLC. Molecular formula: C39H37N5O9. Mole weight: 719.74. | |
| 5'-DMT-2'-deoxyadenosine (N-Ac) | 5'-DMT-2'-deoxyadenosine (N-Ac) is a formidable nucleoside analog with wide-ranging applications. By fragmenting DNA synthesis, the product effectively obstructs the proliferation of malignant cells and viral entities alike. Grades: ≥ 98% by HPLC. Molecular formula: C33H33N5O6. Mole weight: 595.65. | |
| 5'-DMT-2'-deoxyadenosine (N-Bz) | 5'-DMT-2'-deoxyadenosine (N-Bz) is a groundbreaking biomedical compound, rendering it a prime subject of scrutiny in the realm of disease research and nucleoside chemistry. With its profound potential, this compound paves the way for breakthrough researchs targeting intractable malignant tumors and untangling the intricacies of DNA-linked ailments. Grades: ≥ 98% by HPLC. Molecular formula: C38H35N5O6. Mole weight: 657.71. | |
| 5'-DMT-2'-deoxyadenosine (N-Fmoc) | 5'-DMT-2'-deoxyadenosine (N-Fmoc) standing as an indispensable asset, chiefly utilized in the intricate amalgamation of modified nucleic acids. Its extraordinary adaptability serving as an exceptional groundwork, empowering extensive studies on the multifaceted intricacies of DNA-protein interplay, gene manifestation is and nucleic acid-mediated curative modalities. Grades: ≥ 98% by HPLC. Molecular formula: C46H41N5O7. Mole weight: 775.85. | |
| 5'-DMT-2'-deoxyadenosine (N-PAC) | 5'-DMT-2'-deoxyadenosine (N-PAC) is a pivotal bioactive compound persistently applied in the research of ailments like cancer, viral infections and autoimmune disorders. Grades: ≥ 98% by HPLC. Molecular formula: C39H37N5O7. Mole weight: 687.74. | |
| 5'-DMT-2'-deoxycytidine (N-Ac) | 5'-DMT-2'-deoxycytidine (N-Ac) is a pharmacological agent employed in the domain of biomedical research for the exploration of the epigenetic mechanisms responsible for gene expression modulation, with specific attention to the pathogenesis of cancer. Its chemical structure harbors a dimethylthiazolidine ring and an N-acetyl moiety at the 5' position, imparting functional properties closely related to its DNA methyltransferase inhibitory and DNA demethylation-promoting actions, largely responsible for the compound's anti-tumor activity. Grades: ≥ 98% by HPLC. Molecular formula: C32H33N3O7. Mole weight: 571.62. | |
| 5'-DMT-2'-deoxycytidine (N-Bz) | 5'-DMT-2'-deoxycytidine (N-Bz) is a noteworthy biomedical compound, operating as an efficacious antiviral warrior to pursure viral replication while adeptly impeding the development of viral contagions. Grades: ≥ 98% by HPLC. Molecular formula: C37H35N3O7. Mole weight: 633.69. | |
| 5'-DMT-2'-deoxycytidine (N-Fmoc) | 5'-DMT-2'-deoxycytidine (N-Fmoc), a formidable nucleoside analogue revered for its exceptional versatility and ease of use, boasts a captivating array of practical applications as a reagent for solid-phase oligonucleotide synthesis. Unleash your scientific curiosity and uncover novel insights into the diagnosis and treatment of cancers and viral diseases with the unparalleled precision and accuracy of 5'-DMT-2'-deoxycytidine (N-Fmoc). Grades: ≥ 98% by HPLC. Molecular formula: C45H41N3O8. Mole weight: 751.82. | |
| 5'-DMT-2'-deoxycytidine (N-iBu) | 5'-DMT-2'-deoxycytidine (N-iBu) is a highly significant compound extensively employed within the biomedical sector,used for studying multifarious viral infections and malignancies. It has exceptional antiviral and anticancer attributes. Grades: ≥ 98% by HPLC. Molecular formula: C34H37N3O7. Mole weight: 599.67. | |
| 5'-DMT-2'-deoxycytidine (N-PAC) | N-PAC, scientifically known as 5'-DMT-2'-deoxycytidine is an avant-garde biomedical breakthrough, harnessed efficaciously in the research of multifarious ailments. Its remarkable attributes lie in its formidable antiviral potency, primarily targeting DNA viruses, hence imparting immense prospects for delving into viral infection therapy. Grades: ≥ 98% by HPLC. Molecular formula: C38H37N3O8. Mole weight: 663.72. | |
| 5'-DMT-2'-deoxyguanosine (N-Fmoc) | 5'-DMT-2'-deoxyguanosine (N-Fmoc), a chemical utilized in DNA-based drug advances and the synthesis of oligonucleotides, has shown its potential in treating various diseases including cancer, viral infections, and genetic disorders. Additionally, its distinctive structure facilitates targeted drug delivery to specific cells and tissues, ultimately amplifying efficacy levels and minimizing undesired adverse effects. Furthermore, it is also utilized in cutting-edge gene therapy and DNA vaccines research, propelling the development of future healthcare innovations. Grades: ≥ 98% by HPLC. Molecular formula: C46H41N5O8. Mole weight: 791.85. | |
| 5'-DMT-2'-deoxyguanosine (N-iBu) | 5'-DMT-2'-deoxyguanosine (N-iBu) is an immensely potent and esteemed pharmaceutical compound, exhibiting effectiveness in the research of maladies by precisely targeting intricate cellular pathways. Grades: ≥ 98% by HPLC. Molecular formula: C35H37N5O7. Mole weight: 639.7. | |
| 5'-DMT-2'-deoxyguanosine (N-isopropyl-PAC) | 5'-DMT-2'-deoxyguanosine (N-isopropyl-PAC), the chemical stunner, known for exploring DNA structure and function, has attracted the scientific community's attention. Its compelling mechanism of action-encapsulating the natural nucleotides, has supported DNA polymerase and replication research. Additionally, this powerhouse has shown promising therapeutic potential in countering malignancies and select viral infections, opening doors to novel treatment strategies. Grades: ≥ 98% by HPLC. Molecular formula: C42H43N5O8. Mole weight: 745.82. | |
| 5'-DMT-2'-deoxyguanosine (N-PAC) | N-PAC, also referred to as 5'-DMT-2'-deoxyguanosine, proves to be an insightful compound when investigating the impact of carcinogens on DNA. Its usage in biomedicine offers deeper comprehension of tobacco smoke's effects on genetic material, as well as other environmental toxins that may lead to illnesses such as cancer. Grades: ≥ 98% by HPLC. Molecular formula: C39H37N5O8. Mole weight: 703.74. | |
| 5'-DMT-2'-deoxyguanosine (N-tBPAC) | 5'-DMT-2'-deoxyguanosine (N-tBPAC) is a remarkably influential nucleoside analog that has garnered widespread attention in the field of biomedicine. By impeding viral DNA synthesis, it effectively hinders viral replication, culminating in a commendable display of antiviral prowess within infected cells. Grades: ≥ 98% by HPLC. Molecular formula: C43H45N5O8. Mole weight: 759.85. | |
| 5'-DMT-2'-deoxy-isoguanosine (N/N-diisobutylformamidine) | N/N-diisobutylformamidine, also known as 5'-DMT-2'-deoxy-isoguanosine, is an intricate synthetic nucleoside analog utilized in the biomedical industry as an impressive antiviral agent used against the human immunodeficiency virus. This intriguing compound is adept at inhibiting reverse transcriptase activity, ultimately leading to the prevention of viral replication. Additionally, research has demonstrated that its properties may be of use in the treatment of specific cancer types. Grades: ≥ 98% by HPLC. Molecular formula: C40H48N6O6. Mole weight: 708.85. | |
| 5'-DMT-2'-deoxythymidine | 5'-DMT-2'-deoxythymidine, a nucleoside analogue, is frequently utilized as an antiviral agent to target retroviruses, especially those linked to human immunodeficiency virus (HIV) and acquired immunodeficiency syndrome (AIDS). Its function involves obstructing viral reverse transcription and stalling viral replication in affected cells, making it an essential treatment option for those afflicted with retroviral infections. Grades: ≥ 98% by HPLC. Molecular formula: C31H32N2O7. Mole weight: 544.6. | |
| 5'-DMT-2'-O-Me-PseudoUridine-CE-Phosphoramidite | 5'-DMT-2'-O-Me-PseudoUridine-CE-Phosphoramidite is a phosphoramidite derivative used in the synthesis of modified oligonucleotides for biomedical research. It enables the incorporation of 2'-O-methyl-pseudouridine modifications into RNA sequences, enhancing stability and specific RNA-protein interactions. Synonyms: 2'-O-Methyl-5'-O-DMT-pseudoUridine 3'-CE phosphoramidite; pseudoUridine (with 5'-DMT, 3'-phosphoramidite, and 2'-OMe); 2,4(1H,3H)-Pyrimidinedione, 5-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-O-methyl-β-D-ribofuranosyl]-; 5-[5-O-[Bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-O-methyl-β-D-ribofuranosyl]-2,4(1H,3H)-pyrimidinedione. CAS No. 199737-09-2. Molecular formula: C40H49N4O9P. Mole weight: 760.81. | |
| 5'-DMT-2'-(O-methyl)-adenosine (N-Bz) | 5'-DMT-2'-(O-methyl)-adenosine (N-Bz) representing a remarkable biomedical compound primarily acting as an adenosine A2A receptor agonist. It assumes a pivotal function in the intricate regulation of immune reactions. The exceptional chemical configuration of this compound has applications in research of afflictions like Parkinson's disease, multiple sclerosis and persistent inflammatory conditions. Grades: ≥ 98% by HPLC (Isomeric impurity 0 %). Molecular formula: C39H37N5O7. Mole weight: 687.74. | |
| 5'-DMT-2'-(O-methyl)-adenosine (N-PAC) | 5'-DMT-2'-(O-methyl)-adenosine (N-PAC) is a remarkable nucleoside analog, serving as a potent entity with inherent antiviral prowess. Its unrivaled efficacy lies in its exquisite ability to exclusively combat RNA viruses. Grades: ≥ 98% by HPLC. Molecular formula: C40H39N5O8. Mole weight: 717.77. | |
| 5'-DMT-2'-(O-methyl)-cytidine (N-Ac) | 5'-DMT-2'-(O-methyl)-cytidine (N-Ac) is a remarkable biomedical compound, holding immense promise in research of RNA viral infections. Renowned for its robust antiviral efficacy and profound immunomodulatory capabilities, it assumes a pivotal role in constraining viral replication while fostering the emergence of a resilient adaptive immune retort. Grades: ≥ 98% by HPLC (Isomeric impurity 0 %). Molecular formula: C33H35N3O8. Mole weight: 601.65. | |
| 5'-DMT-2'-(O-methyl)-cytidine (N-Bz) | 5'-DMT-2'-(O-methyl)-cytidine (N-Bz) is a highly sophisticated biomedical compound, used in research of an array of menacing viral adversaries encompassing viral hepatitis, HIV and herpes. Its potent antiviral capabilities materialize through the proficient disruption of viral RNA replication mechanisms coupled with the repression of viral proliferative tendencies. Grades: ≥ 98% by HPLC (Isomeric impurity 0 %). Molecular formula: C38H37N3O8. Mole weight: 663.72. | |
| 5'-DMT-2'-(O-methyl)-cytidine (N-PAC) | 5'-DMT-2'-(O-methyl)-cytidine (N-PAC) is a formidable antiviral compound deployed in the research of viral afflictions, with an emphasized efficacy against RNA viruses. Its research of antiviral range expands fervently, encompassing the likes of influenza and hepatitis C. Grades: ≥ 98% by HPLC. Molecular formula: C39H39N3O9. Mole weight: 693.74. | |
| 5'-DMT-2'-(O-methyl)-guanosine (N-iBu) | 5'-DMT-2'-(O-methyl)-guanosine (N-iBu) is a prominent biomedical compound extensively employed in nucleotide chemistry research assuming a paramount significance in fabricating altered nucleotides and probing their plausible ramifications in related developments. Its application in studying antiviral therapies exhibiting substantial potential by deftly manipulating viral replication and protein research and development pathways. Grades: ≥ 98% by HPLC (Isomeric impurity 0 %). Molecular formula: C36H39N5O8. Mole weight: 669.72. | |
| 5'-DMT-2'-(O-methyl)-guanosine (N-PAC) | 5'-DMT-2'-(O-methyl)-guanosine (N-PAC) is a remarkable pharmacological compound, extensively employed in the research of select malignant neoplasms and viral afflictions. Its formidable inhibitory potential derives from its adeptness at thwarting viral RNA and DNA duplication, effectively thwarting the advance of afflictions birthed by these pathogens. Grades: ≥ 98% by HPLC. Molecular formula: C40H39N5O9. Mole weight: 733.77. | |
| 5'-DMT-2'-(O-methyl)-uridine | 5'-DMT-2'-(O-methyl)-uridine is a potent and selective compound utilized in the research of certain diseases, including cancer. Its mechanism of action involves targeting specific cellular pathways, inhibiting tumor growth and promoting apoptosis. Grades: ≥ 98% by HPLC (Isomeric impurity 0 %). Molecular formula: C31H32N2O8. Mole weight: 560.59. | |
| 5'-DMT-2'-O-TBDMS-adenosine (N-Bz) | 5'-DMT-2'-O-TBDMS-adenosine (N-Bz), a chemical compound extensively employed for research purposes within the biomedical sphere, serves as a modified adenosine variation with supplementary TBDMS and Bz chemical groups. Its practical uses encompass drug design in treating diverse medical anomalies including cancer and cardiovascular diseases, primarily due to its therapeutic benefits dictated by anti-inflammatory and anticancer properties. Significantly, research into 5'-DMT-2'-O-TBDMS-adenosine (N-Bz) has fostered a perception of it being a truly promising candidate for better treatment and care methodologies towards these diseases. Grades: ≥ 98% by HPLC (Isomeric impurity < 0.1 %). Molecular formula: C44H49N5O7Si. Mole weight: 787.97. | |
| 5'-DMT-2'-O-TBDMS-adenosine (N/N-diBz) | 5'-DMT-2'-O-TBDMS-adenosine (N/N-diBz) is an exceedingly intricate compound predominantly employed in the research of afflictions encompassing cancer, viral infections and metabolic disorders. Its remarkable attributes extend to its capacity to manipulate and modulate biological pathways and effectively engage with precise drug targets. Grades: ≥ 98% by HPLC (Isomeric impurity < 0.1 %). Molecular formula: C51H53N5O8Si. Mole weight: 892.08. | |
| 5'-DMT-2'-O-TBDMS-adenosine (N-PAC) | 5'-DMT-2'-O-TBDMS-adenosine (N-PAC), a nucleoside analog that presents intriguing therapeutic potential in various forms of cancers, especially lung and breast cancer, opt to impede the uncontrolled division of cancer cells and evoke apoptosis. Apart from its anticancer effects, it shows remarkable immunomodulatory and anti-inflammatory properties, thus highly likely to be used as a potential cure for autoimmune diseases, adding to its versatility and reliability in the medical field. Grades: ≥ 98% by HPLC. Molecular formula: C45H51N5O8Si. Mole weight: 818. | |
| 5'-DMT-2'-O-TBDMS-cytidine (N-Ac) | 5'-DMT-2'-O-TBDMS-cytidine (N-Ac) is a multi-faceted compound that has caught the attention of pharmaceutical researchers worldwide. With its nucleoside analogue properties, this compound exhibits remarkable inhibitory capabilities on DNA replication, thereby influencing the development of antiviral and anticancer agents. Its potential therapeutic properties have also been the focus of investigation for neurological disorders like Alzheimer's and Parkinson's. Its versatile application in mainstream medical research has shown great promise, highlighting its indispensable place in the clinical setting. Grades: ≥ 98% by HPLC (Isomeric impurity < 0.1 %). Molecular formula: C38H47N3O8Si. Mole weight: 701.88. | |
| 5'-DMT-2'-O-TBDMS-cytidine (N-Bz) | 5'-DMT-2'-O-TBDMS-cytidine (N-Bz) is an exceptional nucleoside analog showcasing extraordinary efficacy in research of RNA viruses, including the notorious hepatitis C virus (HCV). Leveraging its distinctive antiviral properties, this compound holds immense potential for the research and development of HCV and various other viral afflictions. Grades: ≥ 98% by HPLC (Isomeric impurity < 0.1 %). Molecular formula: C43H49N3O8Si. Mole weight: 763.95. | |
| 5'-DMT-2'-O-TBDMS-cytidine (N-PAC) | 5'-DMT-2'-O-TBDMS-cytidine (N-PAC) is a potent nucleoside of immense significance in arresting the growth and proliferation of cancerous cells. This invaluable compound can be used in research of a myriad of malignancies spanning lung, colorectal and breast cancer. Grades: ≥ 98% by HPLC. Molecular formula: C44H51N3O9Si. Mole weight: 793.98. | |
| 5'-DMT-2'-O-TBDMS-guanosine (N-iBu) | 5'-DMT-2'-O-TBDMS-guanosine (N-iBu) is a phonetically impressive guanosine analogue that displays remarkable potential as a candidate antiviral drug. Possessing incredible efficacy against the Zika virus, as well as other flaviviruses like dengue and West Nile virus, its proficiency is not limited to antiviral applications alone. It has shown remarkable efficacy in the treatment of specific tumours, establishing its prospects as a promising anticancer agent. Grades: ≥ 98% by HPLC (Isomeric impurity < 0.1 %). Molecular formula: C41H51N5O8Si. Mole weight: 769.96. | |
| 5'-DMT-2'-O-TBDMS-guanosine (N-PAC) | 5'-DMT-2'-O-TBDMS-guanosine (N-PAC), a dynamic and versatile compound utilized to unlock the secrets of nucleic acids, has invaded scientific research for its unparalleled potential. Its applications range from studying protein-nucleotide affinity to the groundbreaking research in antiviral and anticancer drug synthesis. The possibilities of N-PAC are endless and ever-expanding - a laboratory essential for the cutting-edge researcher. Proceed with caution, for once N-PAC enters the lab, there is no going back. Grades: ≥ 98% by HPLC. Molecular formula: C45H51N5O9Si. Mole weight: 834. | |
| 5'-DMT-2'-O-TBDMS-inosine | 5'-DMT-2'-O-TBDMS-inosine is a crucial compound employed in the biomedical industry acting as a biochemical precursor in the development of various drugs used for diseases like cancer, viral infections and autoimmune disorders. This compound plays a vital role in the research of novel pharmaceutical interventions and targeted therapies. Grades: ≥ 98% by HPLC (Isomeric impurity < 0.1 %). Molecular formula: C37H44N4O7Si. Mole weight: 684.85. | |
| 5'-DMT-2'-O-TBDMS-N1-Methyl-PseudoUridine-CE-Phosphoramidite | It is a modified ribonucleoside analogue suitable for incorporation into small interfering RNA (siRNA) to enhance RNA stability in biological applications such as gene silencing. Synonyms: 5'-Dimethoxytrityl-1-methyl-pseudouridine, 2'-O-TBDMS-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; 5-[5-O-[bis(4-methoxyphenyl)?phenylmethyl]?-3-O-[[bis(1-methylethyl)?amino]?(2-cyanoethoxy)?phosphino]?-2-O-[(1,?1-dimethylethyl)?dimethylsilyl]?-β-D-ribofuranosyl]?-1-methyl-2,?4(1H,?3H)?-pyrimidinedione. Grades: ≥98%. CAS No. 875302-45-7. Molecular formula: C46H63N4O9PSi. Mole weight: 875.07. | |
| 5'-DMT-2'-O-TBDMS-PseudoUridine | 5'-DMT-2'-O-TBDMS-PseudoUridine, a modified nucleoside of immense significance, serves as a fundamental constituent in the synthetic construction of altered RNA molecules. Its pseudouridine backbone modification and safeguarded functional groups contribute significantly to its pivotal role as an indispensable instrument in the advancement of RNA-centric therapeutics. This distinctive compound manifests immense potential in the realm of gene therapy and drug delivery systems, exemplifying its ability to target a wide array of ailments such as cancer, viral infections, and genetic anomalies. Synonyms: 5- ( (2S, 3R, 4R, 5R)-5- ( (Bis (4-methoxyphenyl) (phenyl)methoxy)methyl)-3- ( (tert-butyldimethylsilyl)oxy)-4-hydroxytetrahydrofuran-2-yl)pyrimidine-2, 4 (1H, 3H)-dione. CAS No. 144429-56-1. Molecular formula: C36H44N2O8Si. Mole weight: 660.83. | |
| 5'-DMT-2'O-TBDMS-rU Phosphoramidite | 5'-DMT-2'O-TBDMS-rU Phosphoramidite is a classic 2-OTBDMS phosphoramidite used to incorporate U into synthetic oligonucleotides. Synonyms: rU Phosphoramidite; (2R, 3R, 4R, 5R)-2- ( (Bis (4-methoxyphenyl) (phenyl)methoxy)methyl)-4- ( (tert-butyldimethylsilyl)oxy)-5- (2, 4-dioxo-3, 4-dihydropyrimidin-1 (2H)-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite. Grades: 97%. CAS No. 118362-03-1. Molecular formula: C45H61N4O9PSi. Mole weight: 861.04. | |
| 5'-DMT-2'-O-TBDMS-uridine | 5'-DMT-2'-O-TBDMS-uridine is a modified nucleoside commonly used in the synthesis of mRNA for vaccines. The TBDMS protecting group aids in the stability of the mRNA, allowing for increased production and delivery of mRNA-based therapies. Grades: ≥ 98% by HPLC (Isomeric impurity < 0.1 %). Molecular formula: C36H44N2O8Si. Mole weight: 660.83. | |
| 5'-DMT-3'-O-TBDMS-adenosine (N-Bz) | 5'-DMT-3'-O-TBDMS-adenosine (N-Bz) is an indispensable compound widely employed in the biomedical realm. With its distinct structural modification from adenosine, it demonstrates inhibitory prowess in research of viral afflictions, including HIV and hepatitis C. Grades: ≥ 98% by HPLC (Isomeric impurity < 0.1 %). Molecular formula: C44H49N5O7Si. Mole weight: 787.97. | |
| 5'-DMT-3'-O-TBDMS-cytidine (N-Bz) | N-Bz 5'-DMT-3'-O-TBDMS-cytidine, a nucleoside analog with a probing proficiency in studying DNA methylation causation in a number of conditions, cancer included, holds tremendous promise for the biomedicine sector. It indulges in the conclusive assessment of chemotherapeutic drug efficacy in malignancy containment. Its potency builds a striking argument for its indispensability in the domain of nucleoside analog studies and intensive scientific investigation. Grades: ≥ 98% by HPLC (Isomeric impurity < 0.1 %). Molecular formula: C43H49N3O8Si. Mole weight: 763.95. | |
| 5'-DMT-3'-O-TBDMS-guanosine (N-iBu) | 5'-DMT-3'-O-TBDMS-guanosine (N-iBu), a nucleoside derivative, exhibits antiviral and anticancer potential. Research conducted thus far has demonstrated inhibitory effects against hepatitis B virus replication. In addition, it has displayed cytotoxicity towards tumor cells. Although the precise mode of action necessitates further examination, the aforementioned outcomes are encouraging. Grades: ≥ 98% by HPLC (Isomeric impurity < 0.1 %). Molecular formula: C41H51N5O8Si. Mole weight: 769.96. | |
| 5'-DMT-3'-O-TBDMS-PseudoUridine | 5'-DMT-3'-O-TBDMS-PseudoUridine, an essential ingredient in the advancement of nucleic acid therapeutics, demonstrates a pivotal function in the alteration of RNA molecules. This alteration facilitates precise ailment targeting and therapy for a diverse range of afflictions such as viral infections and genetic disorders. CAS No. 144429-58-3. Molecular formula: C36H44N2O8Si. Mole weight: 660.83. | |
| 5'-DMT-3'-O-TBDMS-PseudoUridine-CE-Phosphoramidite | 5'-DMT-3'-O-TBDMS-PseudoUridine-CE-Phosphoramidite, an indispensable compound in the thriving biomedical sector, serves as a pivotal component for oligonucleotide synthesis. This ground-breaking technique unlocks unparalleled potential to combat a myriad of afflictions encompassing cancer, viral infections, and genetic aberrations. Molecular formula: C45H61N4O9PSi. Mole weight: 861.05. | |
| 5'-DMT-3'-O-TBDMS-uridine | 5'-DMT-3'-O-TBDMS-uridine is a highly significant and indispensable compound,serving as a pivotal substrate. It plays a paramount role in the intricate process of fabricating modified nucleosides and nucleotides. Grades: ≥ 98% by HPLC (Isomeric impurity < 0.1 %). Molecular formula: C36H44N2O8Si. Mole weight: 660.83. | |
| 5'-DMT-5-bromo-2'-deoxyuridine | 5'-DMT-5-bromo-2'-deoxyuridine is a highly intricate and perplexing chemical compound, often utilized within the biomedical industry to expertly hinder the proliferation of various cancer cells. With efficient and effective targeting, it has proved to be an indispensable lifesaver in the treatment of different forms of cancer, such as the notoriously difficult-to-treat breast cancer, leukemia, and glioma. Functioning as a nuanced nucleoside analogue, it has shown unquestionable efficacy in disrupting DNA synthesis, leading to the ultimate demise of malignant cells. Grades: ≥ 98% by HPLC. Molecular formula: C30H29BrN2O7. Mole weight: 609.46. | |
| 5'-DMT-5-iodo-2'-deoxycytidine (N/N-diisobutylrylformamidine) | 5'-DMT-5-iodo-2'-deoxycytidine (N/N-diisobutylrylformamidine) is an avant-garde biomedical breakthrough, employed proficiently in research of cancer. Its paramount function encompasses the impediment of malignant cellular proliferation, safeguarding against tumor development. Grades: ≥ 98% by HPLC. Molecular formula: C39H43IN4O8. Mole weight: 822.69. | |
| 5'-DMT-5-iodo-2'-deoxyuridine | 5'-DMT-5-iodo-2'-deoxyuridine is a formidable antiviral compound enlisted in the research of counteracting viral infections, including herpes simplex virus (HSV) and varicella-zoster virus (VZV). By assimilating into the burgeoning DNA strand, this compound erects an impregnable bulwark, halting viral DNA replication and conclusively suffocating its progression. Grades: ≥ 98% by HPLC. Molecular formula: C30H29IN2O7. Mole weight: 656.47. | |
| 5'-DMT-5-methyl-2'-deoxycytidine (N-Bz) | 5'-DMT-5-methyl-2'-deoxycytidine (N-Bz) standing out as an influential chemotherapeutic compound exerting substantial anticancer effects in the research of cancer variants, such as lung, breast and colon cancer. Its prowess lies in hindering DNA research and development and provoking cell cycle arrest, thereby effectively hampering the expansion of malignant tumors. Grades: ≥ 98% by HPLC. Molecular formula: C38H37N3O7. Mole weight: 647.72. | |
| 5'-DMT-5-methyl-cytidine (N-Bz) | 5'-DMT-5-methyl-cytidine (N-Bz) is a potent molecular oncological compound, selectively eradicating malignant cells while sparing their healthy counterparts. Clinical trials confirm its potent efficacy in disrupting malignant protein synthesis, compromising malignant cellular replication and inducing apoptosis. Its highly specific chemical structure is critical for cancer cell targeting, which would revolutionize personalized medicine. Grades: ≥ 98% by HPLC. Molecular formula: C38H37N3O8. Mole weight: 663.72. | |
| 5'-DMT-5-propynyl-2'-deoxycytidine (N-Bz) | 5'-DMT-5-propynyl-2'-deoxycytidine (N-Bz) is an efficacious antiviral agent used to combat viral infections, including Hepatitis B and C. This mighty compound functions by restraining viral DNA synthesis, thereby terminating viral proliferation. By virtue of its high potency, it owes its antiviral activity to its ability to disrupt the reverse transcriptase activity of the virus. Consequently, suppression of viral RNA formation results from its action. As such, it represents a promising novel drug candidate for treating diverse viral diseases. Grades: ≥ 98% by HPLC. Molecular formula: C40H37N3O7. Mole weight: 671.74. | |
| 5'-DMT-5-propynyl-2'-deoxyuridine | 5'-DMT-5-propynyl-2'-deoxyuridine is a nucleoside analogue that has shown antitumor activity against various cancer cell lines, including breast, colon, and lung cancer. It works by incorporating into DNA, causing termination of the DNA chain during replication, leading to cell death. Its potential use in certain chemotherapies is currently being explored. Grades: ≥ 98% by HPLC. Molecular formula: C33H32N2O7. Mole weight: 568.62. | |
| 5'-DMT-5-propynyl-2'-(O-methyl)-cytidine (N-Bz) | 5'-DMT-5-propynyl-2'-(O-methyl)-cytidine (N-Bz) is a highly effective and potent anti-viral compound that finds widespread use in the biomedical industry for treating viral infections such as hepatitis B and C. The distinctive chemical structure of this compound provides numerous clinical advantages concerning efficacy and toxicity, resulting from inhibiting viral replication and reducing viral load simultaneously. Grades: ≥ 98% by HPLC. Molecular formula: C41H39N3O8. Mole weight: 701.76. | |
| 5'-DMT-5-propynyl-2'-(O-methyl)-uridine | 5'-DMT-5-propynyl-2'-(O-methyl)-uridine, a synthetic nucleotide analog, possesses extraordinary anticancer and antiviral activities. This promising tool in biomedical science has been found to exhibit potential antitumor proficiency through the induction of apoptosis and the inhibition of cell metastasis in select types of cancer. Additionally, it has shown to cause a significant reduction in targeted virus replication including HIV and HCV, suggesting crucial usage as an antiviral agent. The modification of the uridine base not only enhances its therapeutic potential but also ensures favorable pharmacological properties, positioning it as the best choice for the development of novel therapies. Grades: ≥ 98% by HPLC. Molecular formula: C34H34N2O8. Mole weight: 598.64. | |
| 5'-DMT-5-propynyl-cytidine (N-Bz) | 5'-DMT-5-propynyl-cytidine (N-Bz) is a groundbreaking nucleoside analog that harbors immense promise in countering challenging viral infections, including hepatitis B and C, by frustrating the replication of viral DNA and RNA. Beyond preventing viral proliferation, the anti-cancer properties of the agent are equally intriguing, inducing cell death by interfering with DNA synthesis. While the clinical potential of the compound is impressive, deep and extensive investigation is necessary to fully unravel the therapeutic conduits of 5'-DMT-5-propynyl-cytidine (N-Bz). Grades: ≥ 98% by HPLC. Molecular formula: C40H37N3O8. Mole weight: 687.74. | |
| 5'-DMT-5-propynyl-uridine | 5'-DMT-5-propynyl-uridine, a modified version of uridine, is a potential therapeutic agent for fighting against neurological diseases including Alzheimer's and Parkinson's. Scientific studies have revealed that it could enhance cognitive function whilst also exhibiting excellent anti-inflammatory properties. With high demand in the biomedical industry, this product holds great promise for those looking to alleviate the negative effects of these devastating diseases. Grades: ≥ 98% by HPLC. Molecular formula: C33H32N2O8. Mole weight: 584.62. | |
| 5'-DMT-7-deaza-2'-deoxyadenosine (N-Bz) | 5'-DMT-7-deaza-2'-deoxyadenosine (N-Bz) is a remarkably potent nucleoside analog renowned for its exceptional antiviral attributes. This compound is indispensably leveraged in studying notorious viral infections, such as HIV and hepatitis B. Grades: ≥ 98% by HPLC. Molecular formula: C39H36N4O6. Mole weight: 656.73. | |
| 5'-DMT-7-deaza-2'-deoxyguanosine (N-iBu) | 5'-DMT-7-deaza-2'-deoxyguanosine (N-iBu): a compound integral to the advancement of antiviral medications against hepatitis B and C. Its exceptional nucleoside analog characteristics enable the inhibition of viral DNA synthesis, inducing viral DNA base-pairing dysfunction, thereby proving efficacious for antiviral treatments. This compound also uniquely supports the study of DNA-protein interactions through its exceptional structural qualities. Grades: ≥ 98% by HPLC. Molecular formula: C36H38N4O7. Mole weight: 638.71. | |
| 5'-DMT-7-deaza-2'-deoxyinosine | 5-DMT-7-deaza-2-deoxyinosine, a nucleoside analogue utilized to suppress the replication of viral DNA, exhibits potent efficacy against viruses such as herpes simplex virus and cytomegalovirus by interfering with the normal function of viral DNA polymerase. Its inhibitory action cripples the virus from proliferating, showcasing its unique ability to hinder viral replication. Grades: ≥ 98% by HPLC. Molecular formula: C32H31N3O6. Mole weight: 553.61. | |
| 5'-DMT-8-bromo-2'-deoxyadenosine (N-Bz) | N-Bz, or 5'-DMT-8-bromo-2'-deoxyadenosine, is a nucleoside analog that exhibits exciting antiviral properties against herpes viruses. Emerging evidence showcases its ability to suppress viral replication via the targeted inhibition of viral DNA polymerase enzymes. Such attributes present an enticing avenue toward treating herpes virus infections, potentially reducing their debilitating effects. Grades: ≥ 98% by HPLC. Molecular formula: C38H34BrN5O6. Mole weight: 736.61. | |
| 5'-DMT-8-bromo-2'-deoxyadenosine (N/N-dibutylformamidine) | 5'-DMT-8-bromo-2'-deoxyadenosine (N/N-dibutylformamidine) is an invaluable compound with sector, showcasing inhibitory efficacy in studying diverse ailments, encompassing viral infections and cancers. Grades: ≥ 98% by HPLC. Molecular formula: C40H47BrN6O5. Mole weight: 771.74. | |
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