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4-Deoxy-3'-beta-C-methyluridine
4-Deoxy-3'-beta-C-methyluridine, a pivotal compound extensively utilized in the biomedical sector across multifarious applications, assumes a paramount role in the advancement of antiviral therapeutics, predominantly against RNA viruses like HIV and hepatitis C. Synonyms: 4-Deoxy-3'-β-C-methyluridine. Grades: ≥95%. CAS No. 1106013-87-9. Molecular formula: C10H14N2O5. Mole weight: 242.23.
4-Deoxy-3'-deoxy-3'-fluorouridine
4-Deoxy-3'-deoxy-3'-fluorouridine is a remarkable antiviral compound, showcasing potency in research of diverse viral ailments, especially those of RNA origin. Its mode of operation primarily revolves around the meticulous hindrance of viral RNA research and development, consequently curtailing viral replication and impeding the rampant dissemination of contagion. Grades: ≥95%. Molecular formula: C9H11FN2O4. Mole weight: 230.19.
4-Deoxy-xylo-uridine
4-Deoxy-xylo-uridine is a remarkable compound, exhibiting exceptional potency in research of combatting viral infections originating from RNA viruses. Through its role as a nucleoside analog, it adeptly disrupts viral RNA research and development, thereby impeding viral replication. Synonyms: Zebularine; 1-β-D-xylofuranosyl-1H-pyrimidin-2-one; 1-((2R,3R,4R,5R)-3,4-Dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-1H-pyrimidin-2-one; 1-(β-D-Xylofuranosyl)-2(1H)-pyrimidinone; 1-[(2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one. Grades: ≥95%. CAS No. 63527-47-9. Molecular formula: C9H12N2O5. Mole weight: 228.20.
4'-Ethynylthymidine
4'-Ethynylthymidine is a nucleoside analog that has shown potential as an antiviral and anticancer agent. It is used to treat viral infections and cancers by inhibiting DNA synthesis in infected/cancerous cells. 4'-Ethynylthymidine has also been studied for its potential use in gene therapy due to its ability to block DNA replication. Synonyms: 4'-alpha-Ethynylthymidine. CAS No. 221272-62-4. Molecular formula: C12H14N2O5. Mole weight: 266.25.
4-Hydroxy-5-[2,3-O-(1-methylethylidene)-5-O-(triphenylmethyl)-L-ribofuranosyl]-1H-pyrazole-3-carboxylic Acid Ethyl Ester is an intermediate in the Pyrazofurin synthesis, an anticancer agent showed to exhibit tumor cell growth inhibitory activity. CAS No. 206269-73-0. Molecular formula: C33H34N2O7. Mole weight: 570.63.
4-Hydroxy-6-methylpyrimidine
6-Methyl-4-hydroxypyrimidine is used in the preparation of antitumor compounds based upon adenine. Also used in the synthesis of novel purimidine, 3-cyanopyridine and m-amino-N-phenylbenzamide derrivatives as tyrosine kinase inhibitors. Synonyms: 6-Methylpyrimidin-4-ol; 6-Methyl-4(3H)-pyrimidinone; 4-Hydroxy-6-methylpyrimidine; 6-METHYL-4-PYRIMIDINOL; 4-Pyrimidinol,6-methyl; 6-methyl-4(1h)-pyrimidinon; 4-methyl-1H-pyrimidin-6-one. Grades: ≥ 95 %. CAS No. 3524-87-6. Molecular formula: C5H6N2O. Mole weight: 110.11.
Used in the 5-modified-2'-dU and 2'-dC preparation as mutagenic anti-HIV-1 proliferation agents. Synonyms: 3',5'-Bis-O-[(1,1-dimethylethyl)dimethylsilyl]-α-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-thymidine-d2. Molecular formula: C28H54D2N2O6Si3. Mole weight: 603.02.
4-MB-cCMP
4-MB-cCMP is an analogue of cCMP, the putative second messenger nucleotide and the main cellular metabolite of DB-cCMP. 4-MB-cCMP exhibits a partial activity of PKG Iα in vitro and in vivo, and a full activity of PKA RIα and PKA RIIα in vitro. Synonyms: N4- Monobutyrylcytidine- 3', 5'- cyclic monophosphate, sodium salt. Grades: ≥ 97% by HPLC. Molecular formula: C13H17N3O8P · Na. Mole weight: 397.3.
4'-Methyl-5-methyluridine
4'-Methyl-5-methyluridine, an essential compound in nucleoside research, should be approached with caution due to its intricate and enigmatic nature. Its multifaceted properties, including potent antiviral and anticancer characteristics, have garnered attention in the realm of biomedical advancements. Synonyms: 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)-5-methyltetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione; 4'-α-C-Methyl-5-methyluridine; Uridine, 5-Methyl-4'-C-Methyl-; 1-[5-Deoxy-4-(hydroxymethyl)-α-L-lyxofuranosyl]-5-methyl-2,4(1H,3H)-pyrimidinedione. Grades: ≥95%. CAS No. 152540-75-5. Molecular formula: C11H16N2O6. Mole weight: 272.25.
4'-Methylthymidine
It shows inhibitory activity against HIV in MT-4 cells. Synonyms: 4'-c-methylthymidine; 1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)-5-methyl-tetrahydrofuran-2-yl]-5-methyl-pyrimidine-2,4-dione; 1-(2-Deoxy-4-C-methyl-β-D-erythro-pentofuranosyl)thymine. Grades: ≥95%. CAS No. 139925-84-1. Molecular formula: C11H16N2O5. Mole weight: 256.26.
4-N3-PET-8-Biotin-11-cGMP
4-N3-PET-8-Biotin-11-cGMP is a cGMP analogue used for photoaffinity labelling of cGMP-responsive receptors. Grades: ≥ 95% by HPLC. Molecular formula: C36H44N12O10PS2 · Na. Mole weight: 922.9.
4-N3-PET-8-Br-cGMP
4-N3-PET-8-Br-cGMP is an analogue used for photoaffinity labelling of cGMP-responsive receptors, and an isozyme-selective activator of cGMP-dependent protein kinase I α and &beta. Synonyms: β- (4- Azidophenyl)- 1, N2- etheno- 8- bromoguanosine- 3', 5'- cyclic monophosphate, sodium salt. Grades: ≥ 97% by HPLC. Molecular formula: C18H13BrN8O7P · Na. Mole weight: 587.2.
4'-Nitrobenzoyl-6-selenoinosine
4'-Nitrobenzoyl-6-selenoinosine is a drug used for biomedical research in the treatment of certain types of cancer and viral infections. It is a derivative of inosine with a nitrobenzoyl group attached to carbon 4 and a selenium atom replacing the oxygen at position 6. Its chemical properties make it a potential antitumor and antiviral agent, but further studies are needed to fully understand its mechanism of action. Synonyms: 2-(hydroxymethyl)-5-[6-[(4-nitrophenyl)methylselanyl]purin-9-yl]oxolane-3,4-diol; p-nitrobenzyl-6-selenopurine riboside; Se-(p-Nitrobenzyl)-6-selenoinosine; 6-(p-Nitrobenzyl)selenopurine riboside; (2R,3S,4R,5R)-2-(hydroxymethyl)-5-[6-[(4-nitrophenyl)methylselanyl]purin-9-yl]oxolane-3,4-diol. CAS No. 40144-12-5. Molecular formula: C17H17N5O6Se. Mole weight: 466.31.
4-Thio-2'-deoxythymidine
4-Thio-2'-deoxythymidine is a highly efficacious antiviral derivative of thymidine prevalent in the compound sector, showcasing remarkable proficiency in curtailing DNA and RNA viruses, encompassing herpesviruses, HIV is and hepatitis B virus. By hampering the research and development of nucleic acids, this compound efficaciously impedes viral replication. Grades: ≥ 98% by HPLC. Molecular formula: C10H14N2O4S. Mole weight: 258.3.
4-Thio-2'-deoxyuridine
4-Thio-2'-deoxyuridine is a nucleoside analog, widely employed for the targeted research of viral infections caused by the herpes simplex and varicella-zoster viruses. By effectively impeding the research and development of viral DNA, it manifests its potent antiviral attributes. Notably, due to its unique thio substitution, this compound augments antiviral efficacy while concurrently mitigating any potential cytotoxic effects. Grades: ≥ 98% by HPLC. Molecular formula: C9H12N2O4S. Mole weight: 244.27.
4'-Thiocytidine
4'-Thiocytidine, a compound of utmost importance, finds valuable application within the biomedical sphere, serving as an imperative agent for the exploration and advancement of antiviral therapeutics. Its significance lies in its pivotal contribution to the amalgamation of nucleoside analogues, specifically targeting the remedy of viral afflictions like hepatitis B and C. Synonyms: 1-(4-Thio-beta-D-ribofuranosyl)cytosine; Cytidine, 4'-thio-; Tarac; 4-Amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-hydroxymethyl-tetrahydro-thiophen-2-yl)-1H-pyrimidin-2-one. Grades: ≥95%. CAS No. 93080-09-2. Molecular formula: C9H13N3O4S. Mole weight: 259.28.
4-THIO-DU CEP
4-THIO-DU CEP is a potent compound used to research urinary tract infections caused by bacteria. It acts by inhibiting the enzymes responsible for bacterial cell wall research and development, effectively stopping their growth. Synonyms: 5'-Dimethoxytrityl-2'-deoxy-4-(2-cyanoethylthio)-Uridine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; 4-Thio-dU-CE Phosphoramidite. Grades: 95%. CAS No. 144303-74-2. Molecular formula: C42H50N5O7PS. Mole weight: 799.93.
4-Thio-ethyl-UTP
4-Thio-ethyl-UTP, a compound extensively utilized in biomedical research, particularly in the field of RNA splicing and editing, is an immensely versatile alternative substrate to UTP, especially when investigating the function of RNA editing enzymes. Its exclusive selectivity for specific RNA sequences further enhances its usefulness, rendering it an essential tool for studying cancer and genetic disorders. Synonyms: 4-Thio-ethyl-uridine-5'-triphosphate, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C11H19N2O14P3S (free acid). Mole weight: 528.26 (free acid).
4-Thio-i-butyl-UTP
4-Thio-i-butyl-UTP, a nucleotide analogue utilized in biomedical studies, offers a unique opportunity to investigate RNA structure and function. With a wide range of applications, it plays a critical role in researching RNA-dependent processes in enzymatic assay systems. Moreover, recent studies have unveiled its antiviral properties, indicating its potential as a powerful drug development candidate for targeting specific viral infections. Synonyms: 4-Thio-iso-butyl-uridine-5'-triphosphate, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C13H23N2O14P3S (free acid). Mole weight: 556.31 (free acid).
4'-Thioinosine
4'-Thioinosine, a purine nucleoside analog utilized within the biomedical industry to study adenosine transport inhibition's effects on tumor growth. Its potential as a treatment for autoimmune diseases, like rheumatoid arthritis, has been established via the suppression of inflammatory pathways. Synonyms: NSC 90420; 9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)thiolan-2-yl]-1H-purin-6-one; Inosine, 4'-thio-. Grades: ≥95%. CAS No. 58004-19-6. Molecular formula: C10H12N4O4S. Mole weight: 284.29.
4-Thio-i-propyl-UTP
4-Thio-i-propyl-UTP, a biochemical compound used in biomedical research, is known for its efficacy in the evaluation of P2Y receptor function. Scientists heavily rely on it to look at signaling pathways implicated in diseases affecting multiple organ systems such as cancer, diabetes, and neurodegenerative disorders. This substrate has the power to activate adenylate cyclase through P2Y receptor-mediated processes. Studying these receptors using this compound has been shown to shed light on pathogenic mechanisms. Its use is well-established across the scientific community, both in vitro and in vivo. Synonyms: 4-Thio-iso-propyl-uridine-5'-triphosphate, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C12H21N2O14P3S (free acid). Mole weight: 542.27 (free acid).
4-Thio-methyl-UTP
4-Thio-methyl-UTP is an intricate compound commonly employed in the realm of investigative research and diagnostics. This distinctive altered nucleotide analog effortlessly integrates into RNA throughout transcription, bestowing itself as a paramount instrument for scrutinizing DNA research and development and RNA alterations. Notably, it showcases exceptional utility in delving into the significant role that precise nucleotides play in influencing the intricate facets of RNA's structural composition and functional behavior. Synonyms: 4-Thio-methyl-uridine-5'-triphosphate, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C10H17N2O14P3S (free acid). Mole weight: 514.23 (free acid).
4-Thio-n-propyl-UTP
4-Thio-n-propyl-UTP is a fundamental biosynthetic molecule,finding multifarious applications in examining the intricate dynamics of RNA research and development and modification. Its existence is a profound comprehension of intricate cellular processes concerning gene expression and regulation can be attained. Additionally, owing to its remarkable attributes, 4-Thio-n-propyl-UTP assumes a critical role in unraveling the nuances of RNA metabolism and development. Synonyms: 4-Thio-n-propyl-uridine-5'-triphosphate, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C12H21N2O14P3S (free acid). Mole weight: 542.29 (free acid).
4-Thiothymidine
4-Thiothymidine, a nucleoside analogue, exhibits potent antiviral activity by inhibiting DNA replication. This sulfur-containing compound specifically targets thymidine kinase, an enzyme essential for DNA synthesis, which offers promising applications in antiviral therapies. Notably, its efficacy has been observed against HIV and hepatitis B, making it a valuable research tool in biomedical studies. The intricate biochemistry of 4-Thiothymidine highlights its potential for further investigations and development of novel therapeutic agents. Synonyms: 4-Thio-D-thymidine; 1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methyl-4-thioxo-3,4-dihydropyrimidin-2(1H)-one; 4-Thiodeoxythymidine; 1-(2-deoxy-beta-D-erythro-pentofuranosyl)-5-methyl-4-thioxo-3,4-dihydropyrimidin-2(1H)-one; 3,4-Dihydro-5-methyl-1-(2-deoxy-β-D-ribofuranosyl)-4-thioxopyrimidin-2(1H)-one. Grades: ≥98% by HPLC. CAS No. 7236-57-9. Molecular formula: C10H14N2O4S. Mole weight: 258.29.
4-Thio-UDP
4-Thio-UDP, in the realm of compound industry, standing as a prominent biochemical compound of significant usage. Exhibiting itself as a substrate for multifarious enzymes governing intricate cellular processes, it has garnered attention due to its potential therapeutic implications concerning nucleotide metabolism and signaling pathways. Its paramountcy in research pertaining to cancer, neurodegenerative disorders and immune system impairments remains undeniable. Synonyms: 4-Thio-uridine-5'-diphosphate, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C9H14N2O11P2S (free acid). Mole weight: 420.22 (free acid).
4-Thio-UMP
4-Thio-UMP is a modified nucleoside used to treat various types of cancer and viral infections. It works by selectively inhibiting DNA and RNA synthesis in cancer cells or virus-infected cells, leading to their death. Its anti-tumor activity has been demonstrated in preclinical models of colon, breast, and lung cancer. Additionally, 4-Thio-UMP has also been shown to have antiviral effects against several RNA viruses such as influenza A, hepatitis C, and Zika virus. Synonyms: 4-Thio-uridine-5'-monophosphate, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C9H13N2O9PS (free acid). Mole weight: 340.24 (free acid).
4-Thio-uridine
4-Thio-uridine is a prominent biomedical compound renowned for its formidable anti-viral capabilities. By impeding viral replication while concurrently attenuating inflammation, 4-Thio-uridine plays an important role in the research of these deleterious conditions. Grades: ≥ 98% by HPLC. Molecular formula: C9H12N2O5S. Mole weight: 260.27.
4'-Thiouridine
4'-Thiouridine is a nucleoside analogue employed in the biomedical sector for investigative endeavors, predominantly within nucleic acid examinations. Its assimilation into RNA molecules facilitates the exploration of RNA's intricate framework and its inherent functionalities. Research elucidating RNA editing mechanisms and the ramifications of nucleoside modifications on genetic expression finds immense utility in this compound. Synonyms: 1-(4-Thio-beta-D-ribofuranosyl)uracil; Uridine, 4'-thio-; 4'-O-Thiauridine; 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrothiophen-2-yl)pyrimidine-2,4(1H,3H)-dione. Grades: ≥95%. CAS No. 6741-73-7. Molecular formula: C9H12N2O5S. Mole weight: 260.27.
4-Thiouridine-5'-triphosphate sodium salt
4-Thiouridine-5'-triphosphate sodium salt, a nucleotide analogue extensively employed as a substrate for RNA polymerases, has evoked a plethora of diverse inquiries to investigate the intricate mechanisms of RNA editing and splicing. Significantly, its unique attributes permit specific positioning and labeling of RNA strands, attributing to unparalleled detectability, purification, and quantification. Synonyms: 4-Thio-utp. Molecular formula: C9H15N2O14P3S·4Na. Mole weight: 592.17.
4-Thio-UTP
4-Thio-UTP is an agonist of P2Y2 and P2Y4 receptors that can influence on transcription process to terminate chain extension. Synonyms: 4-Thiouridine-5'-Triphosphate; Thio UTP. Grades: ≥ 95% by HPLC. CAS No. 31556-28-2. Molecular formula: C9H15N2O14P3S (free acid). Mole weight: 500.20 (free acid).
4-Triazolyl-dU-CEP
4-Triazolyl-dU-CEP is a notable and significant compound, exhibiting paramount importance in the research and development of nucleoside analogs. Specifically, this compound serves as a pivotal intermediate in the progression of antiviral medications, specifically nucleotide polymerase inhibitors. Synonyms: 5'-Dimethoxytrityl-2'-deoxy-4-Triazolyl-Uridine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; O4-Triazolyl-dU-CE Phosphoramidite. Grades: 95%. CAS No. 109389-31-3. Molecular formula: C41H48N7O7P. Mole weight: 781.84.
50-Carboxycyanocobalamin
Vitamin B12 Monocarboxylic Acid is an impurity of Vitamin B12 which is a water-soluble vitamin with a key role in the normal functioning of the brain and nervous system, and for the formation of blood. Synonyms: Vitamin B12 e-Monocarboxylic Acid; Co-(cyano-κC)?-cobinic acid-abcdg-pentamide dihydrogen phosphate (ester)?, inner salt, 3'-ester with (5,?6-dimethyl-1-α-D-ribofuranosyl-1H-benzimidazole-κN3); Cobinic acid-abcdg-pentamide, cyanide hydroxide. Grades: > 95%. CAS No. 26264-28-8. Molecular formula: C63H87CoN13O15P. Mole weight: 1356.35.
5-(1-Propynyl)-2'-deoxycytidine
5-(1-Propynyl)-2'-deoxycytidine is a potent antiviral compound used in research of a range of DNA and RNA viruses, including hepatitis B and C viruses, HIV is and herpes simplex viruses. This nucleoside analog inhibits viral DNA research and development, thus hindering viral replication. Synonyms: Cytidine, 2'-deoxy-5-(1-propynyl)-; Cytidine,2'-deoxy-5-(1-propyn-1-yl)-; Cytidine, 2'-deoxy-5-(1-propyn-1-yl)-; 4-amino-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-prop-1-ynylpyrimidin-2-one; 2'-deoxy-5-propynylcytidine; 5-Propynyl-2'-deoxycytidine;2'-deoxy-5-(1-propyn-1-yl)-cytidine; 5-(1-PROPYNYL)-2/'-DEOXYCYTIDINE;4-amino-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-(prop-1-ynyl)pyrimidin-2(1H)-one. Grades: ≥ 90%. CAS No. 117693-24-0. Molecular formula: C12H15N3O4. Mole weight: 265.27.
5-(1-Propynyl)-2'-O-methylcytidine
5-(1-Propynyl)-2'-O-methylcytidine is a robust and efficacious antiviral compound, finding profound utility in the research of various virological malaises such as respiratory syncytial virus (RSV), influenza and hemorrhagic fever viruses. Its mechanism of action lies in thwarting viral replication and averting viral dissemination within the host organism. Synonyms: 4-amino-1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]-5-prop-1-ynylpyrimidin-2-one; Cytidine, 2'-O-methyl-5-(1-propynyl)- (9CI); 4-Amino-1-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)-5-(prop-1-yn-1-yl)pyrimidin-2(1H)-one; 2'-O-Methyl-5-prop-1-yn-1-ylcytidine; Cytidine,2'-O-methyl-5-(1-propynyl)-(9ci); 4-amino-1-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)-5-(prop-1-ynyl)pyrimidin-2(1H)-one. Grades: ≥ 95%. CAS No. 179817-96-0. Molecular formula: C13H17N3O5. Mole weight: 295.29.
5-(1-Propynyl)-2'-O-methyluridine
5-(1-Propynyl)-2'-O-methyluridine is a remarkable potent antiviral compound acting as an expert inhibitor of RNA viruses, boasting an ability to curb the notorious influenza virus. Synonyms: 1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]-5-prop-1-ynylpyrimidine-2,4-dione; 1-((2R,3R,4R,5R)-4-Hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)-5-(prop-1-yn-1-yl)pyrimidine-2,4(1H,3H)-dione;2'-O-Methyl-5-prop-1-yn-1-yluridine; 5-(1-PROPYNYL)-2/'-O-METHYLURIDINE; Uridine,2'-O-methyl-5-(1-propynyl)-(9ci); 1-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)-5-(prop-1-ynyl)pyrimidine-2,4(1H,3H)-dione. Grades: ≥ 97%. CAS No. 179817-95-9. Molecular formula: C13H16N2O6. Mole weight: 296.28.
5-(2-Amino-2-oxoethyl)-2-thiouridine
5-(2-Amino-2-oxoethyl)-2-thiouridine is a modified nucleoside that can be incorporated into RNA, specifically in the anticodon loop of transfer RNA (tRNA). This unique modification helps to increase the accuracy of codon recognition during translation, which is important in preventing errors that can lead to disease such as cancer. It has also shown anti-tumor activity in in vitro studies and has potential for therapeutic use in cancer treatment. Synonyms: 5-Aminocarbonylmethyl-2-thiouridine; 5-(Carbamoylmethyl)-2-thiouridine; 5-(2-Amino-2-oxoethyl)-1-(β-D-ribofuranosyl)-2-thioxo-2,3-dihydro-4(1H)-pyrimidinone; 2-[1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-4-oxo-2-thioxo-1,2,3,4-tetrahydro-pyrimidin-5-yl]-acetamide. Grades: ≥95%. CAS No. 29900-40-1. Molecular formula: C11H15N3O6S. Mole weight: 317.32.
5-(2-Azidoethyl)cytidine
5-(2-Azidoethyl)cytidine is an extraordinary biomedical compound, distinguished by its distinctive azidoethyl group. Its paramount functionality lies in its profound ability to manipulate cellular mechanisms and engage with intricate biological systems, thereby paving the way for research in targeted therapies and avant-garde drug delivery mechanisms. Grades: ≥95%. Molecular formula: C11H16N6O5. Mole weight: 312.28.
5-(2-Azidoethyl)uridine
5-(2-Azidoethyl)uridine, a modified nucleoside utilized in biomedical research, has been discovered to display potential antiviral properties. As such, numerous studies have explored its applicability in treating various viral diseases, including HIV and hepatitis C. Furthermore, it is a celebrated tool for analyzing RNA structure and function, and has provided invaluable insights into this field. Grades: ≥95%. Molecular formula: C11H15N5O6. Mole weight: 313.27.
5-(2-Hydroxyethyl)-2',3'-di-O-toluoyl-2'-deoxyuridine is a remarkable and multifaceted biomedical compound, emerging as a resolute solution to study malicious viral invasions, particularly the notorious herpes. Synonyms: [(2R,3S,5R)-5-[5-(2-hydroxyethyl)-2,4-dioxopyrimidin-1-yl]-3-(4-methylbenzoyl)oxyoxolan-2-yl]methyl 4-methylbenzoate; (2R, 3S, 5R) -5- (5- (2-hydroxyethyl) -2, 4-dioxo-3, 4-dihydropyrimidin-1 (2H) -yl) -2- ( (4-methylbenzoyloxy) methyl) tetrahydrofuran-3-yl 4-methylbenzoate; 2'-Deoxy-5-(2-hydroxyethyl)-3',5'-bis-O-(4-methylbenzoyl)uridine; 3,5-Di-O-(P-toluoyl)-5-(2-Hydroxyethyl)-2-deoxyuridine. Grades: ≥95%. Molecular formula: C27H28N2O8. Mole weight: 508.52.
5-(2-Hydroxyethyl)-2-deoxyuridine
It is a novel effective antiviral nucleoside analogue. Synonyms: 5-(2-Hyroxyethyl)-2'-deoxyuridine; 2-Deoxy-5-(2-hydroxyethyl)uridine; 2'-Deoxy-5-(2-hydroxyethyl)uridine; 1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-(2-hydroxyethyl)pyrimidine-2,4(1H,3H)-dione; 5-(2-hydroxyethyl)-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidine-2,4-dione. Grades: ≥95%. CAS No. 90301-60-3. Molecular formula: C11H16N2O6. Mole weight: 272.25.
5-(2-Hydroxyethyl)uridine
5-(2-Hydroxyethyl)uridine, a modified nucleoside commonly used in RNA research, exhibits excellent RNA stability and translation efficiency, rendering it valuable for gene expression studies. In addition to its utility in the laboratory, recent studies revealed promising therapeutic potential for treating mitochondrial illnesses. Synonyms: 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-(2-hydroxyethyl)pyrimidine-2,4(1H,3H)-dione; Uridine, 5-(2-hydroxyethyl)-. Grades: ≥95%. CAS No. 102691-28-1. Molecular formula: C11H16N2O7. Mole weight: 288.25.
5-(2-(Trimethylsilyl)-1-ethyn-1-yl)-1-(2',3',5'-tri-O-acetyl-β-D-ribofuranosyl)imidazo-4-carbonitrile, a highly sophisticated biomedical product, holds immense potential in the realm of cancer treatment. Functioning as a formidable inhibitor, this compound diligently halts the relentless growth and proliferation of cancer cells. Its exceptional prowess lies in its ability to selectively target these malignant entities by obstructing their DNA replication while concurrently impeding the activity of crucial enzymes vital to tumor progression. Synonyms: 1-(2,3,5-Tri-O-acetyl-β-D-ribofuranosyl)-5-[(trimethylsilyl)ethynyl]-1H-imidazole-4-carbonitrile. Grades: 95%. CAS No. 126004-21-5. Molecular formula: C20H25N3O7Si. Mole weight: 447.51.
5-(3-Aminophenyl)-2'-deoxyuridine
5-(3-Aminophenyl)-2'-deoxyuridine, a highly esteemed compound within the compound industry, demonstrates remarkable antiviral capabilities through its selective impediment of DNA viral replication in afflicted cells. Synonyms: Uridine, 5-(3-aminophenyl)-2'-deoxy-. CAS No. 188482-60-2. Molecular formula: C15H17N3O5. Mole weight: 319.31.
5-(3-Azidopropyl)-2'-deoxyuridine
5-(3-Azidopropyl)-2'-deoxyuridine is a nucleoside analogue serving as a potent antiviral compound, exhibiting promising applications in research of various viral diseases, particularly those induced by herpes viruses. The incorporation of the distinctive azidopropyl functional group renders this compound highly valuable for drug discovery and viral investigation purposes. Grades: ≥ 95% by HPLC. Molecular formula: C12H17N5O5. Mole weight: 311.29.
5-(3-Azidopropyl)cytidine
5-(3-Azidopropyl)cytidine is an indispensable compound, playing a pivotal role in the research and development of antiviral medications to combat different viral afflictions such as HIV and herpes. Its distinctive configuration facilitates targeted interaction with viral enzymes, effectively impeding their functionality and thereby suppressing viral replication. Synonyms: 5-(3-Azidopropyl)cytidine; HY-152787. Grades: ≥95%. Molecular formula: C12H18N6O5. Mole weight: 326.31.
5-[3-(Trifluoroacetamido)-1-(E)-propenyl]uridine
5-[3-(Trifluoroacetamido)-1-(E)-propenyl]uridine is used in the biomedical industry for its potential role in studying viral diseases. It may have antiviral properties due to the presence of uridine derivatives and the trifluoroacetamido group. Synonyms: N-((E)-3-(1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)allyl)-2,2,2-trifluoroacetamide; 5-TFA-aa-uridine; 5-TFA-aa-U; (E)-5-[3-(Trifluoroacetamido)-1-propenyl]uridine; 5-{(1E)-3-[(Trifluoroacetyl)amino]-1-propen-1-yl}uridine. Grades: ≥98% by HPLC. CAS No. 869222-68-4. Molecular formula: C14H16F3N3O7. Mole weight: 395.29.
5-[3-[ (Trifluoroacetyl) amino]propyl]uridine
5-[3-[ (Trifluoroacetyl) amino]propyl]uridine, a groundbreaking biomedical solution, exerts its antiviral prowess against RNA viruses. This scientific compound intricately hinders viral replication and adeptly curtails burdensome viral load. Synonyms: Uridine, 5-[3-[(trifluoroacetyl)amino]propyl]-. Grades: ≥95%. CAS No. 327623-80-3. Molecular formula: C14H18F3N3O7. Mole weight: 397.30.
5'-(4-Fluorosulfonylbenzoyl)adenosine HCl
5'-(4-Fluorosulfonylbenzoyl)adenosine HCl - a versatile chemical compound that has been instrumental in biomedical research. Its study has been critical in understanding various cellular processes, including the role of adenosine. Furthermore, it has been used in the development of novel drugs to combat diseases like cancer, HIV, and neurological disorders - all of which can be traced back to aberrant adenosine signaling. Synonyms: FSBA; Adenosine-5'-(4-fluorosulfonylbenzoate) hydrochloride; Adenosine, 5'-[4-(fluorosulfonyl)benzoate], monohydrochloride(9CI); Adenosine, 5'-[4-(fluorosulfonyl)benzoate], hydrochloride (1:1); 5-Fsba; ((2R,3S,4R,5R)-5-(6-Amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl 4-(fluorosulfonyl)benzoate hydrochloride. Grades: 97%. CAS No. 78859-42-4. Molecular formula: C17H17ClFN5O7S. Mole weight: 489.86.
5,6-Dichloro-1-(b-D-ribofuranosyl)benzimidazole
5,6-Dichloro-1-β-D-ribofuranosylbenzimidazole (DRB) is a chemical compound that inhibits transcription elongation by RNA Polymerase II. It is used in research to study underlying mechanisms of cellular regulation. Sensitivity to DRB is dependent on DRB sensitivity inducing factor (DSIF), negative elongation factor (NELF), and positive transcription elongation factor b (P-TEFb). DRB is a nucleoside analog and also inhibits some protein kinases. Uses: Nucleic acid synthesis inhibitors. Synonyms: DRB; 5,6-Dichloro-1-beta-D-ribofuranosylbenzimidazole; Dichlororibofuranosylbenzimidazole; 5,6-Dichlorobenzimidazole riboside. Grades: ≥ 98%. CAS No. 53-85-0. Molecular formula: C12H12Cl2N2O4. Mole weight: 319.15.
A protected inhibitor used for RNA synthesis, which could cause premature termination of transcription. Synonyms: 5,6-Dichloro-1-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)-1H-benzimidazole. CAS No. 443678-71-5. Molecular formula: C18H18Cl2N2O7. Mole weight: 445.25.
5,6-Dihydro-5'-O-DMT-thymidine 3'-CE phosphoramidite, a modified form of thymidine boasting a dimethoxytrityl group for stability during synthesis and a phosphate for solid support attachment, is a key component in synthesizing oligonucleotides used in studying disease and gene therapy. Its versatility has made it a popular material in researching illnesses including cystic fibrosis, Alzheimer's, and cancer. Synonyms: 5,6-Dihydro-D-thymidine 3'-CE phosphoramidite. Molecular formula: C40H51N4O8P. Mole weight: 746.83.
5,6-Dihydro-ara-uridine
5,6-Dihydro-ara-uridine is an exemplary pharmaceutical compound, exhibiting antiviral and antineoplastic properties in the research of malignancies, encompassing leukemia and solid tumors. By impeding DNA enhancement and fostering apoptosis in malignant cells, 5,6-Dihydro-ara-uridine presents a strikingly potent solution. Synonyms: 1-(β-D-Arabinofuranosyl)dihydro-2,4(1H,3H)-pyrimidinedione; 1-((2R,3S,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)dihydropyrimidine-2,4(1H,3H)-dione. Grades: ≥95%. CAS No. 30100-83-5. Molecular formula: C9H14N2O6. Mole weight: 246.22.
5,6-Dihydro-UTP
5,6-Dihydro-UTP, a nucleotide analog, displays agonist activity at P2Y receptors and serves as a beneficial tool in the study of said receptors in biomedical research. Its multifaceted potential, including implications for the treatment of diseases like cancer and diabetes, make it an exceedingly valuable addition to experimental studies. Synonyms: 5,6-Dihydrouridine-5'-Triphosphate. Grades: ≥90% by AX-HPLC. Molecular formula: C9H17N2O15P3. Mole weight: 486.16.
5,6-DM-cBIMP
5,6-DM-cBIMP is an activator of phosphodiesterase type II and it has a slight activated effect for protein kinase G. Synonyms: 5, 6- Dimethylbenzimidazole riboside- 3', 5'- monophosphate, sodium salt. Grades: ≥ 98% by HPLC. CAS No. 142754-31-2. Molecular formula: C14H16N2O6P · Na. Mole weight: 362.3.
5-Acetoxymethyl-2'-deoxyuridine
5-Acetoxymethyl-2'-deoxyuridine is an esteemed compound, used in research of targeting the nefarious viral infections thrust upon innocent hosts by the herpes simplex virus (HSV). Exhibiting its prowess as a precursor, this extraordinary compound orchestrates its transformation into an activated state within the confines of infected cells, vehemently thwarting the pernicious research and development of viral DNA. Synonyms: [1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-2,4-dioxopyrimidin-5-yl]methyl acetate; rac-N-?[(1R)?-?2-?Hydroxy-?3-?methyl-?1-?(2-?methylpropyl)?-?3-?buten-?1-?yl]?-?carbamic Acid 1,?1-?Dimethylethyl Ester. Grades: 97%. CAS No. 148380-55-6. Molecular formula: C12H16N2O7. Mole weight: 300.26.
5'-Acetyl-2',3'-isopropylidene Adenosine
5'-Acetyl-2',3'-isopropylidene Adenosine, a highly advanced and multifunctional bioactive compound, plays a pivotal role in the realm of cutting-edge biomedical research. Synonyms: 2',3'-O-Isopropylidene-5'-O-acetyladenosine; 2',3'-O-(1-Methylethylidene)adenosine 5'-Acetate; NSC 90373. Grades: 97%. CAS No. 15888-38-7. Molecular formula: C15H19N5O5. Mole weight: 349.34.
5-AcOHg-dCTP
5-AcOHg-dCTP is a crucial nucleotide analog used in compound for various applications playing a significant role in the study of DNA sequencing due to its unique properties. It is commonly used in the diagnosis and research of viral infections, such as HIV. Synonyms: 5-Mercuriacetat-2'-deoxycytidine-5'-triphosphate, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C11H18HgN3O15P3 (free acid). Mole weight: 725.78 (free acid).
5-AcOHg-dUTP
5-AcOHg-dUTP, a modified nucleotide with applications in both research and diagnostics, serves as a pivotal tool for incisive study of DNA replication and repair while also bearing immense potential in the development of advanced disease detection techniques, as a cancer and viral infection marker. Synonyms: 5-Mercuryacetat-2'-deoxyuridine-5'-triphosphate, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C11H17HgN2O16P3 (free acid). Mole weight: 726.77 (free acid).
5'-Adenylic acid monoanhydride with (dichlorophosphonomethyl)phosphonic acid
5'-Adenylic acid monoanhydride with (dichlorophosphonomethyl)phosphonic acid is a compound commonly utilized as a research instrument to scrutinize nucleotide metabolism and regulation. Additionally, it is reputed to have potential and promising therapeutic applications in treating viral diseases, including HIV and herpes simplex virus. Synonyms: 5'-Adenylic acid, monoanhydride with (dichlorophosphonomethyl)phosphonic acid; Bgd-ATP; 81336-74-5; beta,gamma-Dichloromethane-ATP; [[ (2R, 3S, 4R, 5R) -5- (6-aminopurin-9-yl) -3, 4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy- (dichlorooxyphosphorylmethyl) phosphinic acid; Adenosine 5'-(beta,gamma-dichloromethylene) triphosphate; Adenosine-5'-O-(beta,gamma-dichloromethane)triphosphate; DTXSID801001930; 9-{5-O-[{[{[Bis (chlorooxy)phosphoryl]methyl} (hydroxy)phosphoryl]oxy} (hydroxy)phosphoryl]pentofuranosyl}-9H-purin-6-amine. CAS No. 81336-74-5. Molecular formula: C11H16Cl2N5O12P3. Mole weight: 574.10.
5'-Adenylic acid monoanhydride with (difluorophosphonomethyl) phosphonic acid
5'-Adenylic acid monoanhydride with (difluorophosphonomethyl) phosphonic acid, a compound extensively used in the biomedical sector, has been widely acknowledged as an antiviral drug par excellence for the management of herpes virus infections. Its modus operandi involves curtailing viral DNA synthesis, which, in turn, impedes the proliferation and transmission of viruses. Its efficacy is unequivocal, rendering it a go-to recommendation for medical practitioners. In certain cases, it is judiciously combined with other antiviral therapies to augment its efficiency. Synonyms: Amppcf2P; 81336-78-9; 5'-Adenylyl (beta,gamma-difluoromethylene)diphosphonate; 5'-Adenylic acid monoanhydride with (difluorophosphonomethyl)phosphonic acid; 5'-Adenylic acid, monoanhydride with (difluorophosphonomethyl)phosphonic acid. CAS No. 81336-78-9. Molecular formula: C11H16F2N5O10P3. Mole weight: 509.19.
5-Amino-1-(2',3',5'-tri-O-acetyl-β-D-ribofuranosyl)-imidazole-4-carboxamide is an extensively employed pharmaceutical compound, used in the research of afflictions, most notably cancer and viral infections. Perturbing pivotal cellular mechanisms, it effectively retards the proliferation and duplication of malignant cells or infectious compounds. Synonyms: 5-Amino-1-β-D-ribofuranosyl-imidazole-4-carboxamide 2',3',5'-Triacetate;AICAR-Tri-O-Acetate; NSC 157736. Grades: 95%. CAS No. 23274-21-7. Molecular formula: C15H20N4O8. Mole weight: 384.34.
5-Amino-2'-O-methyluridine hydrochloride
5-Amino-2'-O-methyluridine hydrochloride is a critical bioactive component harnessed in biomedical research, manifesting formidable antiviral attributes. Its application encompasses the realm of pharmaceuticals, wherein it contributes to the development of therapeutic compounds tailored to combat viral onslaughts, such as herpes simplex, cytomegalovirus and varicella-zoster virus. Grades: ≥95%. Molecular formula: C10H16ClN3O6. Mole weight: 309.70.
5-Amino-3-β-D-ribofuranosylthiazolo[4,5-d]pyrimidin-2,7(3H,6H)-dione is an important ingredients in some antiviral agents, exhibitting great efficacy in combatting enigmatic RNA virus-inflicted maladies. 5-Amino-3-β-D-ribofuranosylthiazolo[4,5-d]pyrimidin-2,7(3H,6H)-dione unequivocally impeding virulence dissemination and the perpetual replication, widely applied to research of influenza, hepatitis C, and HIV. Grades: ≥ 97%. CAS No. 122970-40-5. Molecular formula: C10H12N4O6S. Mole weight: 316.29.
5'-Amino-5'-deoxy-5'-N-MMT-thymidine 3'-CE phosphoramidite, a compound of utmost importance in the biomedical sector, serves as a pivotal entity for crafting modified oligonucleotides. Leveraging its inherent amino and thymidine elements, this phosphoramidite contributes significantly to the advancement of nucleic acid-centered therapeutics, diagnostics, and gene expression investigations. Synonyms: 5'-monomethoxytritylamino-2'-deoxyThymidine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; 5'-Amino-dT-CE Phosphoramidite. CAS No. 194034-71-4. Molecular formula: C39H48N5O6P. Mole weight: 713.81.
5'-Amino-5'-deoxyadenosine
It is an adenosine kinase inhibitor. Synonyms: 5'-Amino-5'-deoxy-D-adenosine; 5'-NH2-Ado; (2R,3R,4S,5R)-2-(6-Amino-9H-purin-9-yl)-5-(aminomethyl)tetrahydrofuran-3,4-diol; NSC 238990; 5'-Deoxy-5'-aminoadenosine. Grades: ≥95%. CAS No. 14365-44-7. Molecular formula: C10H14N6O3. Mole weight: 266.26.
5'-Amino-5'-deoxythymidine
It is used in the methods and compositions for treatment of anti-angiogenic resistant cancer. Synonyms: NSC 169339; 1-((2R,4S,5R)-5-(Aminomethyl)-4-hydroxytetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione; 5-Addot; 5'-Amino-2',5'-dideoxythymidine; 5'-deoxy-5'-aminothymidine. Grades: ≥95%. CAS No. 25152-20-9. Molecular formula: C10H15N3O4. Mole weight: 241.24.
5-Aminoallyl 2'-deoxycytidine-5'-triphosphate lithium salt-100mM aqueous solution is a vital reagent in the biomedical industry. This product is commonly used for labeling DNA or RNA during synthesis. It is also an essential tool for detecting mutations and gene expressions, allowing for further research in diseases such as cancer, dementia, and HIV. Synonyms: 5-(3-Aminoallyl)-2'-deoxycytidine-5'-triphosphate, lithium salt; 5-AA-dCTP. Molecular formula: C12H17N4O13P3·4Li. Mole weight: 545.97.
5-Aminoallyl-2'-deoxyuridine
5-Aminoallyl-2'-deoxyuridine is a highly prized compound, finding its extensive utility across diverse applications particularly in the realms of molecular biology and bioconjugation studies. The compound assumes a pivotal position in DNA labeling, amplification techniques and hybridization to facilitate the progress of targeted therapeutics, diagnostic assays and innovative drug delivery systems. CAS No. 87980-17-4. Molecular formula: C12H18N4O4. Mole weight: 282.30.