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5'-DMT-8-bromo-2'-deoxyguanosine (N-iBu)
5'-DMT-8-bromo-2'-deoxyguanosine (N-iBu) is a crucial intermediary compound that is frequently harnessed in the manufacture of nucleoside analogues meant for treating viral infections, particularly hepatitis B and C. However, it is not just another run-of-the-mill small molecule. Indeed, researchers and practitioners alike have come to recognize it for its unique utility as a scientific tool for investigating nucleoside metabolism as well as drug resistance mechanisms. Grades: ≥ 98% by HPLC. Molecular formula: C35H36BrN5O7. Mole weight: 718.59.
5'-DMT-8-bromo-adenosine (N/N-dibutylformamidine)
5'-DMT-8-bromo-adenosine (N/N-dibutylformamidine), a chemical compound extensively employed in biomedical research, is a highly promising modulator of adenosine receptors offering potential applications as an effective anti-cancer therapeutic in inhibiting cancer cell growth. Furthermore, current studies suggest that this compound could be a viable option to treat various neurological disorders including Parkinson's disease. Its marked effectiveness gives hope to further developments in the field of treating complex diseases. Grades: ≥ 98% by HPLC. Molecular formula: C40H47BrN6O6. Mole weight: 787.74.
5'-DMT-adenosine (N-Bz)
5'-DMT-adenosine (N-Bz) emerges as a remarkably robust and focused activator, exhibiting profound selectivity towards the adenosine A1 receptor. Its strong affinity has garnered significant scientific interest in comprehending the intricate involvement of adenosine receptors across diverse physiological spectrums. Grades: ≥ 98% by HPLC. Molecular formula: C38H35N5O7. Mole weight: 673.71.
5'-DMT-adenosine (N-Fmoc)
5'-DMT-adenosine (N-Fmoc) standing as an exceptional biomedical compound, extensively deployed to study select diseases fusing the advantageous attributes of 5'-DMT-adenosine and the safeguarding prowess of N-Fmoc. Grades: ≥ 98% by HPLC. Molecular formula: C46H41N5O8. Mole weight: 791.85.
5'-DMT-adenosine (N-PAC)
5'-DMT-adenosine (N-PAC) is a remarkable biomedical compound, used to study intricate cardiovascular maladies like cardiac arrhythmias and coronary artery diseases. Its profound efficacy derives from its exquisite modulation of adenosine receptors. Grades: ≥ 98% by HPLC. Molecular formula: C39H37N5O8. Mole weight: 703.74.
5'-DMT-cytidine (N-Ac)
5'-DMT-cytidine (N-Ac) is a nucleoside analog, widely used in the biomedical industry for treating various types of cancers and viral infections. It acts as an antiproliferative agent by inhibiting DNA synthesis and induces apoptosis in cancer cells. Furthermore, it also exhibits antiviral activity against several viruses like cytocidal activity against Hepatitis B and C virus. Grades: ≥ 98% by HPLC. Molecular formula: C32H33N3O8. Mole weight: 587.62.
5'-DMT-cytidine (N-Bz)
5'-DMT-cytidine (N-Bz) is a prodigious inhibitor, unveiling its tremendous potential in studying cancer. It dexterously directs its assault towards specific enzymes intricately entwined in the delicate processes of DNA replication and repair. Grades: ≥ 98% by HPLC. Molecular formula: C37H35N3O8. Mole weight: 649.69.
5'-DMT-cytidine (N-Fmoc)
5'-DMT-cytidine (N-Fmoc) is a prominent research chemical in the biomedicine industry. Its utilization is widespread, with its effectiveness being investigated in the activity of cytidine analogues subjected to N-terminus modification. Such research is imperative for the production of new drugs with greater potency intended for cancer and viral disease treatment. Grades: ≥ 98% by HPLC. Molecular formula: C45H41N5O9. Mole weight: 767.82.
5'-DMT-cytidine (N-iBu)
5'-DMT-cytidine (N-iBu), an immensely potent antiviral nucleoside analog, conspicuously stands out in treating viral infections, for instance, the stubborn hepatitis B and C. Chemical biochemistry declares that it breaks in and incapacitates the viral DNA polymerase, curtailing the growth and spread of viruses within the body. Comprising of therapeutic powers beyond the virulent world, preliminary studies have also legitimized its probable role in the treatment of certain cancer genres. Grades: ≥ 98% by HPLC. Molecular formula: C34H37N3O8. Mole weight: 615.67.
5'-DMT-cytidine (N-PAC)
5'-DMT-cytidine (N-PAC), a compelling prospective anti-cancer drug, operates via regulation of DNA methylation, a key contributor to the progression of malignant tumors. Encouraging outcomes have emerged, evidently indicating its potential effectiveness in treating lung cancer, leukemia, and other malignancies. Grades: ≥ 98% by HPLC. Molecular formula: C38H37N3O9. Mole weight: 679.72.
5'-DMT-guanosine (N-Fmoc)
5'-DMT-guanosine (N-Fmoc). A derivative of nucleotides, this compound has far-reaching applications in biomedical research - chiefly, but not exclusively, in the creation of oligonucleotides. Fantastic potential is expected for new developments in treatments for cancer, viral infections, and other such diseases, with this compound acting as a key starting material. Grades: ≥ 98% by HPLC. Molecular formula: C46H41N5O9. Mole weight: 807.85.
5'-DMT-guanosine (N-iBu)
5'-DMT-guanosine (N-iBu) is an indispensable compound specifically aiming in studying neurological ailments such as Alzheimer's disease and Parkinson's disease. Grades: ≥ 98% by HPLC. Molecular formula: C35H37N5O8. Mole weight: 655.7.
5'-DMT-guanosine (N-PAC)
N-PAC, also known as 5'-DMT-guanosine, is an intriguing nucleotide analogue that holds promise in chemical biology research. Among its many properties, it stands out as a selective inhibitor of Francisella tularensis, the causative agent of tularemia. But that's just the tip of the iceberg- N-PAC may also have exciting implications for chemotherapy treatment of triple-negative breast cancer. With its multifaceted potential, N-PAC is a compound that is sure to pique the interest of researchers and clinicians alike. Grades: ≥ 98% by HPLC. Molecular formula: C39H37N5O9. Mole weight: 719.74.
5'-DMT-N3-methyl-2'-deoxythymidine
5'-DMT-N3-methyl-2'-deoxythymidine is a vital compound playing a crucial role in studying and developing diagnostic tools and antiviral therapies for diseases like HIV/AIDS. It can be used to study viral replication and design potent antiretroviral drugs making it an indispensable tool in the fight against viral infections. Grades: ≥ 98% by HPLC. Molecular formula: C32H34N2O7. Mole weight: 558.62.
5'-DMT-PseudoUridine
5'-DMT-PseudoUridine, a pivotal compound within the field of biomedicine, plays a profound and indispensable part in the therapeutic approach towards various diseases, enabling the alteration of RNA molecules. Its unparalleled characteristics not only bolster RNA stability but also foster heightened protein synthesis and regulate cellular mechanisms. Synonyms: SCHEMBL1750218; 144429-55-0; 5- ( (2S, 3R, 4S, 5R)-5- ( (Bis (4-methoxyphenyl) (phenyl)methoxy)methyl)-3, 4-dihydroxytetrahydrofuran-2-yl)pyrimidine-2, 4 (1H, 3H)-dione. CAS No. 144429-55-0. Molecular formula: C30H30N2O8. Mole weight: 546.57.
5'-DMT-uridine
5'-DMT-uridine is a remarkable compound, exhibiting its efficacy in the research of neurodegenerative disorders, such as Alzheimer's and Parkinson's disease. It has unparalleled ability to induce neuroregeneration and shield neurons from oxidative stress. Grades: ≥ 98% by HPLC. Molecular formula: C30H30N2O8. Mole weight: 546.57.
5-Ethoxymethyluridine
5-Ethoxymethyluridine, a remarkable biomedicine, stands as an invaluable asset for combatting an extensive array of diseases. Functioning as a nucleoside analog, it significantly hinders viral replication, rendering it indispensable in the battle against RNA viruses. Synonyms: 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-(ethoxymethyl)pyrimidine-2,4-dione. Grades: ≥95%. CAS No. 95468-92-1. Molecular formula: C12H18N2O7. Mole weight: 302.28.
5-Ethyl-4-thiouridine
5-Ethyl-4-thiouridine is a paramount biomedical compound, intricately contributing to nucleotide research. Profoundly utilized as a chemical probe in RNA modification studies, this compound augments inquiries into the ramifications of thiouridine on RNA's structure and functionality. Manifesting its significance in relation to ailments encompassing cancer, RNA-related disorders and viral infections, it fosters comprehension of its disease-associated role. Synonyms: Uridine, 5-ethyl-4-thio-; 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-ethyl-4-thioxo-3,4-dihydropyrimidin-2(1H)-one. Grades: ≥95%. CAS No. 148744-32-5. Molecular formula: C11H16N2O5S. Mole weight: 288.32.
A useful template for the development of A2B adenosine receptor agonists. It was confirmed to be a full agonist in a functional assay based on the measurement of its capacity to modulate cAMP levels in CHO cells expressing the hA2B receptor. Synonyms: 1-(6-Amino-9H-purin-9-yl)-1-deoxy-N-ethyl-2,3-O-(1-methylethylidene)-β-D-ribofuranuronamide; 2',3'-O-isopropylidene-NECA. CAS No. 39491-53-7. Molecular formula: C15H20N6O4. Mole weight: 348.36.
5'-Ethylcarboxamido-adenosine
5'-Ethylcarboxamido-adenosine, a remarkable biomedicine, exhibits its prowess in cancer therapeutics. This extraordinary compound operates as an adenosine receptor agonist, effectively restraining the proliferation of malignant cells while orchestrating apoptosis. Uses: Vasodilator agents. Synonyms: NECA; 1-(6-Amino-9H-purin-9-yl)-1-deoxy-N-ethyl-b-D-ribofuranuronamide; 5'-Ethylcarboxamido-D-adenosine. Grades: ≥ 95% by HPLC. CAS No. 35920-39-9. Molecular formula: C12H16N6O4. Mole weight: 308.29.
5-Ethylcytidine
5-Ethylcytidine is a vital compound extensively used in the biomedical industry for developing antiviral and antitumor drugs. Synonyms: 5-ethyl-cytidine; 4-Amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-ethylpyrimidin-2(1H)-one. Grades: ≥95%. CAS No. 56367-98-7. Molecular formula: C11H17N3O5. Mole weight: 271.27.
5-Ethynyl-1-(2',3',5'-tri-O-tert-butyldimethylsilyl-β-D-ribofuranosyl)imidazo-4-carbonitrile is a compound useful in organic synthesis. Synonyms: 5-Ethynyl-1-[2,3,5-tris-O-[(1,1-dimethylethyl)dimethylsilyl]-β-D-ribofuranosyl]-1H-imidazole-4-carbonitrile. CAS No. 147212-83-7. Molecular formula: C29H53N3O4Si3. Mole weight: 592.01.
5-Ethynyl-1-(β-D-ribofuranosyl)-imidazo-4-carbonitrile is a compound useful in organic synthesis. Synonyms: 1-[(2R,3R,4S,5R)-3,4-DIHYDROXY-5-(HYDROXYMETHYL)OXOLAN-2-YL]-5-ETHYNYLIMIDAZOLE-4-CARBONITRILE; 1H-Imidazole-4-carbonitrile, 5-ethynyl-1-beta-D-ribofuranosyl-; 5-Ethynyl-1-(beta-D-ribofuranosyl)-imidazo-4-carbonitrile; SCHEMBL9697576; CHEMBL4463936; OAMMFSMFVAEFOI-GWOFURMSSA-N; 5-ETHYNYL-1-(B-D-RIBOFURANOSYL)-IMIDAZO-4-CARBONITRILE; 5-Ethynyl-1-(?-D-ribofuranosyl)-imidazo-4-carbonitrile; 5-ethynyl-1-beta-D-ribofuranosylimidazole-4-carbonitrile. CAS No. 126004-13-5. Molecular formula: C11H11N3O4. Mole weight: 249.22.
5-Ethynyl-2'-deoxy-cytidine (5-EdC)
5-Ethynyl-2'-deoxy-cytidine (5-EdC) is an ethynyl-labeled deoxycytidine. It is incorporates into replicating DNA to measures de novo DNA synthesis during S-phase. Synonyms: 5-Ethynyl-2'-deoxycytidine. Grades: ≥ 99% by HPLC. Molecular formula: C11H13N3O4. Mole weight: 251.24.
5-Fluoro-1-(β-D-ribopyranosyl)-2,4(1H,3H)-pyrimidinedione is a remarkable compound, showcasing its antiviral properties. This concoction exerts a inhibitory efficacy against certain RNA virus strains. Its modus operandi lies in its adeptness at impeding viral replication through disruption of the intricate enhancement of viral genetic material. Synonyms: 2,4(1H,3H)-Pyrimidinedione, 5-fluoro-1-β-D-ribopyranosyl-; 5-fluoro-1-((2R,3R,4R,5R)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)pyrimidine-2,4(1H,3H)-dione. Grades: ≥95%. CAS No. 77180-80-4. Molecular formula: C9H11FN2O6. Mole weight: 262.19.
5-Fluoro-2'-O-methyl-4-(methylithio)uridine
5-Fluoro-2'-O-methyl-4-(methylithio)uridine is a potent compound, garnering significant attention owing to its exceptional efficacy in research of a myriad of viral infections. Its mechanism of action lies in proficiently inhibiting viral replication. Synonyms: 5-Fluoro-1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]-4-methylsulfanylpyrimidin-2-one; 5-FLUORO-2'-O-METHYL-4-(METHYLTHIO)PYRIMIDIN-2-ONE. Grades: 95%. CAS No. 869222-67-3. Molecular formula: C11H15FN2O5S. Mole weight: 306.22.
5-Fluoro-2'-O-methyl-4-thiouridine
5-Fluoro-2'-O-methyl-4-thiouridine is an esteemed compound, unraveling itself through potent antiviral attributes. With astute acumen, this compound assiduously curbs viral replication, emerging as an invaluable asset in the research of influenza infection. Synonyms: 5-FLUORO-2'-O-METHYL-4-THIOURIDINE. Grades: 95%. CAS No. 869355-51-1. Molecular formula: C10H13FN2O5S. Mole weight: 292.29.
5-Fluoro-2'-O-methyluridine
5-Fluoro-2'-O-methyluridine is a highly bioactive nucleoside compound, finding extensive utilization in the research and development of groundbreaking antiviral medications. Boasting remarkable potential, this compound showcases inhibitory efficacy against distinct RNA viruses. Synonyms: 5-Fluoro-2'-O-methyl-D-uridine; 5-Fluoro-1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]pyrimidine-2,4-dione. CAS No. 61671-80-5. Molecular formula: C10H13FN2O6. Mole weight: 276.22.
5-Fluoro-3'-beta-C-methyluridine
5-Fluoro-3'-beta-C-methyluridine is an immensely powerful antiviral entity, exhibiting inhibitory efficacy against select RNA viruses, notably hepatitis C virus and Zika virus. Focusing on its modus operandi, it exerts its effects by markedly impeding theenhancement and replication of viral RNA. Synonyms: 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)-4-methyloxolan-2-yl]-5-fluoropyrimidine-2,4-dione; 5-Fluoro-3'-C-methyluridine. Grades: ≥95%. Molecular formula: C10H13FN2O6. Mole weight: 276.22.
5-Fluoro-4'-thio-cytidine
5-Fluoro-4'-thio-cytidine is a remarkably potent antiviral compound extensively employed in the biomedical sector, acting a cytidine-derived substance. This compound proves integrally indispensable for research of combatting viral maladies. Grades: ≥95%. Molecular formula: C9H12FN3O4S. Mole weight: 277.27.
5-Fluoro-4'-thiouridine
5-Fluoro-4'-thiouridine is an influential pharmaceutical compound, used for studying diverse ailments, encompassing leukemia, pancreatic cancer and viral afflictions. Its inhibitory effects against both viruses and cancer cells are attributed to the inhibition of RNA enhancement and the initiation of apoptosis. Synonyms: Uridine, 5-fluoro-4'-thio-; 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)thiolan-2-yl]-5-fluoropyrimidine-2,4-dione. Grades: ≥95%. CAS No. 56527-42-5. Molecular formula: C9H11FN2O5S. Mole weight: 278.26.
5-Fluoro-6-iodouridine
5-Fluoro-6-iodouridine is an exceptionally powerful compound with remarkable antiviral attributes due to its distinctive amalgamation of fluorine and iodine moieties. It operates by proficiently impeding viral replication while concurrently diminishing the viral burden. Synonyms: 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-fluoro-6-iodopyrimidine-2,4-dione. Grades: ≥ 95%. CAS No. 87818-06-2. Molecular formula: C9H10FIN2O6. Mole weight: 388.09.
5-Fluoro Cytidine
5-Fluoropyrimidine nucleotides as RNA structure probe using 19F-NMR spectroscopy. Synonyms: 5-Fluorocytidine; 5F-C; 4-Amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-fluoropyrimidin-2(1H)-one; 4-Amino-5-fluor-1-(β-D-ribofuranosyl)pyrimidin-2(1H)-one; L-β-Ribofuranosyl-5-fluoro-cytosine. Grades: ≥95%. CAS No. 2341-22-2. Molecular formula: C9H12FN3O5. Mole weight: 261.21.
5-Fluorocytosine arabinoside
5-Fluorocytosine arabinoside, an exceptionally powerful antineoplastic agent extensively applied for the management of diverse malignancies such as leukemia and solid tumors, expertly imparts its therapeutic effects through the restraint of DNA synthesis and the instigation of cellular demise. Synonyms: 4-amino-1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-fluoropyrimidin-2-one; Fluorocytosine arabinoside; Arafluorocytosine; Ara-FC; 4-amino-1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-fluoro-pyrimidin-2-one. Grades: 98%. CAS No. 4298-10-6. Molecular formula: C9H12FN3O5. Mole weight: 261.21.
5-Fluoro-dUMP
5-Fluoro-dUMP is a reagent used in the synthesis of diaminomitosene nucleotide derivatives with antineoplastic activity. Synonyms: (5F-dUMP); 5-Fluoro-2'-deoxyuridine-5'-monophosphate, Sodium salt. Grades: ≥ 95% by HPLC. CAS No. 88410-68-8. Molecular formula: C9H12N2O8PF (free acid). Mole weight: 326.17 (free acid).
5-Fluoro-dUTP
5-Fluoro-dUTP is used as the substitute for DNA synthesis catalyzed by DNA polymerases a or Ãfrom calf thymus. 5-Fluoro-dUTP is incorporated into DNA and the incorporated pyrimidine analogs supported further elongation of DNA. Synonyms: 5-F-dUTP; 5-Fl-dUTP; 5-Fluoro-2'-deoxyuridine-5'-Triphosphate. Grades: ≥ 95% by HPLC. Molecular formula: C9H14N2O14P3F (free acid). Mole weight: 486.13 (free acid).
5-Fluoro-O4-(2,4,6-trimethylphenyl)-2'-deoxyuridine can be used in method for using 5-flucytosine for real-time monitoring the deamination process of HIV-1 DNA. Synonyms: 2'-Deoxy-5-fluoro-4-O-(2,4,6-trimethylphenyl)uridine; 2'-Deoxy-5-fluoro-4-O-(2,4,6-trimethylphenyl)-uridine. CAS No. 141120-63-0. Molecular formula: C18H21FN2O5. Mole weight: 364.37.
5-Fluoro-O4-(2,4,6-trimethylphenyl)-2'-O-methyluridine can be used in pharmacological activity and biological study of compositions and methods for severe acute respiratory syndrome (SARS) treatment. Synonyms: 5-fluoro-2'-O-methyl-4-O-(2,?4,?6-trimethylphenyl)?-uridine. CAS No. 444788-89-0. Molecular formula: C19H23FN2O6. Mole weight: 394.39.
5-Fluoro-UMP
5-Fluoro-UMP, a potent antineoplastic nucleotide analog, is utilized to combat several forms of cancer. It thwarts the synthesis of RNA and DNA by disturbing their natural cellular processes, ultimately culminating in apoptosis. Moreover, it's a key research tool to assess how changes in nucleotide metabolism can impact cellular maturation and proliferation. Synonyms: 5F-UMP; 5-Fluorouridine-monophosphate; Fosfluoridine; 5-Fluorouridylic acid; 5-Fluoro-Uridine-5'-Monophosphate; 5-fluorouridine 5'-(dihydrogen phosphate); 5-Fluoro-4-hydroxy-1-(5-O-phosphonopentofuranosyl)pyrimidin-2(1H)-one; ((2R,3S,4R,5R)-5-(5-Fluoro-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl dihydrogen phosphate. Grades: ≥95% by HPLC. CAS No. 796-66-7. Molecular formula: C9H12FN2O9P. Mole weight: 342.17.
5-Fluoro-UTP is an DNA/RNA synthesis inhibitor that terminate synthesis of nucleotide through inhibiting thymidylate synthase. It is used as an anticancer drug. Uses: 5-fluoro-utp is an dna/rna synthesis inhibitor. Synonyms: (5F-UTP); 5-Fluoro-uridine-5'-triphosphate, Sodium salt. Grades: ≥ 95% by HPLC. CAS No. 3828-96-4. Molecular formula: C9H14N2O15P3F (free acid). Mole weight: 502.13 (free acid).
5-Formyl-2',3'-O-(1-methylethylidene)-cytidine
5-Formyl-2',3'-O-(1-methylethylidene)-cytidine is an intermediate in 5-Formylcytidine synthesis. 5-Formylcytidine is a modified nucleoside found at the first position of the anticodon of bovine mitochondrial tRNAMet. Synonyms: 5-Formyl-2',3'-O-(1-methylethylidene)cytidine; Furo[3,4-d]-1,3-dioxole Cytidine Deriv. CAS No. 153535-36-5. Molecular formula: C13H17N3O6. Mole weight: 311.29.
5-formylcytidine
5-Formylcytidine is a modified nucleoside found at the first position of the anticodon of bovine mitochondrial tRNAMet. Synonyms: Cytidine, 5-formyl-; 4-Amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidine-5-carbaldehyde; cytidine, 6-formyl-. Grades: 98%. CAS No. 148608-53-1. Molecular formula: C10H13N3O6. Mole weight: 271.23.
5-Hydroxy-2'-deoxycytidine
5-Hydroxy-2'-deoxycytidine have been used as a substrate for uracil DNA N-glycosylase and has been used to study the oxidation of DNA due to exposure to reactive oxygen species. Synonyms: 2'-Deoxy-5-hydroxy-cytidine. CAS No. 52278-77-0. Molecular formula: C9H13N3O5. Mole weight: 243.22.
5-Hydroxy-2'-deoxycytidine-5'-Triphosphate
5-Hydroxy-2'-deoxycytidine-5'-Triphosphate is a fundamental recompound, holding immense significance in the exploration of DNA enhancement and repair mechanisms. Facilitating the operation of DNA polymerase, it serves as a substrate, skillfully incorporating 5-hydroxy-2'-deoxycytidine within the DNA research and development process. By unravelling the consequences of oxidative impairment on DNA, this exceptional compound contributes to the research of molecular pathways implicated in ailments like cancer and neurodegenerative disorders. Synonyms: 5-Hydroxy-dCTP; 5-OH-dCTP. Grades: ≥90% by AX-HPLC. Molecular formula: C9H16N3O14P3. Mole weight: 483.10.
5-Hydroxy-2'-O-methyluridine
5-Hydroxy-2'-O-methyluridine is a valuable compound commonly used in the biomedical industry. With its unique structure, it exhibits great potential in the field of antiviral drug development. Studies have shown its efficacy in targeting certain RNA viruses, such as hepatitis C virus and respiratory syncytial virus, to inhibit viral replication. Grades: ≥95%. CAS No. 2030403-78-0. Molecular formula: C10H14N2O7. Mole weight: 274.23.
5-Hydroxy-arabinouridine
5-Hydroxy-arabinouridine is a remarkable compound, effectively impeding the expansion of aberrant cells, while concurrently evoking programmed cell death. Moreover, this awe-inspiring compound exhibiting the potential to synergistically augment the efficacy of various anticancer compounds when administered concomitantly. Synonyms: 1-(β-D-Arabinofuranosyl)-5-hydroxy-2,4(1H,3H)-pyrimidinedione; 1-((2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-hydroxypyrimidine-2,4(1H,3H)-dione; Cytarabine Impurity 17; 1-β-D-Arabinofuranosyl-5-hydroxyuracil; NSC 117925. Grades: ≥95%. CAS No. 69321-95-5. Molecular formula: C9H12N2O7. Mole weight: 260.20.
5-Hydroxy-DC cep
5-Hydroxy-DC cep is an extraordinary bioactive compound, having the ability to meticulously target and repress malignant cells by thwarting pivotal pathways mediated by anomalous enzymes and receptors. Synonyms: N-Benzoyl-3'-O-[ (2-cyanoethoxy) (diisopropylamino)phosphino]-5- (benzoyloxy)-5'-O- (4, 4'-dimethoxytrityl)-2'-deoxycytidine. Grades: 95%. CAS No. 197579-70-7. Molecular formula: C53H56N5O10P. Mole weight: 954.
5-Hydroxymethyl-2',3'-di-O-isopropylidene-2-thiouridine is a profoundly effective compound, meticulously utilized for research of pernicious viral infections triggered by RNA viruses. Its exceptional antiviral characteristics stem from its remarkable affinity towards targeting specific viral enzymes, unfolding a paradigm shift towards obstructing viral replication and mitigating virus-induced pathogenesis. Synonyms: 5-(hydroxymethyl)-1-((3aR,4R,6R,6aR)-6-(hydroxymethyl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one; 2'-O,3'-O-Isopropylidene-5-(hydroxymethyl)-2-thiouridine; 5-(hydroxymethyl)-2',3'-O-(1-methylethylidene)-2-thio-uridine; 5-(Hydroxymethyl)-1-(2,3-O-isopropylidene-β-D-ribofuranosyl)-2-thioxo-2,3-dihydro-4(1H)-pyrimidinone. Grades: ≥95%. CAS No. 58479-71-3. Molecular formula: C13H18N2O6S. Mole weight: 330.36.
5-Hydroxymethyl-2'-C-methyluridine
5-Hydroxymethyl-2'-C-methyluridine is a remarkable compound,functioning as an esteemed nucleoside analogue. It adeptly curtails viral replication while propelling disarray within the tumor cell proliferation. Synonyms: 5-Hydroxymethyl-2'-β-C-methyluridine; 1-[(2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)-3-methyloxolan-2-yl]-5-(hydroxymethyl)pyrimidine-2,4-dione. Grades: ≥95%. CAS No. 2305415-92-1. Molecular formula: C11H16N2O7. Mole weight: 288.25.
5-Hydroxymethyl-2'-deoxycytidine cyclic carbamate
5-Hydroxymethyl-2'-deoxycytidine cyclic carbamate is a formidable compound, showcasing its inhibitory prowess in research of combatting specific cancer strains. This compound operates as a potent DNA demethylating compound, effectively hindering DNA methylation and consequently reawakening tumor suppressor genes. Grades: 95%. CAS No. 1257247-41-8. Molecular formula: C11H13N3O6. Mole weight: 283.24.
5-(Hydroxymethyl)-2'-deoxyuridine
5-(Hydroxymethyl)-2'-deoxyuridine is a nucleoside analog with anticancer and antiviral activities. It inhibits the replication of murine S180 lung carcinoma cells and Ehrlich ascites mammary carcinoma cells (ED50s = 8.5 and 4 μM, respectively) and multiple human leukemia cell lines (IC50s = 1.7-5.8 μM). 5-(Hydroxymethyl)-2'-deoxyuridine acts synergistically with 5-fluorouracil (5-FU) against HT-29, HCT116, PANC-1, and EKVX cancer cells with no effect on WI38 embryonic lung fibroblasts. Uses: Antineoplastic agents. Synonyms: a-hydroxythymidine; 5-Hydroxymethyl-2'-deoxyuridine; alpha-Hydroxythymidine; 5-Hydroxymethyldeoxyuridine; HMdU; 5-HMdU; 2'-Deoxy-5-(hydroxymethyl)uridine; 1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)-5-(2-hydroxymethyl)pyrimidine-2,4(1H,3H)-dione. Grades: ≥95%. CAS No. 5116-24-5. Molecular formula: C10H14N2O6. Mole weight: 258.23.
5-hydroxymethylcytidine
5-Hydroxymethylcytidine is a product in DNA hydroxymethylation. The concentrations of 5-Hydroxymethylcytidine in the brain were used for Alzheimer's disease study. Synonyms: 5-Hydroxymethyl cytidine; Cytidine, 5-(hydroxymethyl)-; 5-(Hydroxymethyl)cytidine; 4-amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-(hydroxymethyl)pyrimidin-2(1H)-one; 5-hydroxymethyl-1-(β-D-ribofuranosyl)cytosine. Grades: ≥95%. CAS No. 19235-17-7. Molecular formula: C10H15N3O6. Mole weight: 273.24.
5-Hydroxymethyl-dCTP
5-Hydroxymethyl-dCTP, a nucleoside triphosphate analog, is a versatile molecular tool extensively utilized by researchers globally in DNA sequencing for molecular investigations investigating epigenetic modifications and associated mechanisms. Its applications in the diagnosis and treatment of conditions such as cancer and infectious diseases are noteworthy too. Synonyms: 5-hme-dCTP; 5-hmdCTP; 5-Hydroxymethyl-2'-deoxycytidine-5'-Triphosphate; 2'-deoxy-5-hydroxymethyl-CTP; 2'-Deoxy-5-hydroxymethylcytidine-5'-triphosphate; 2'-deoxy-5-(hydroxymethyl)cytidine 5'-(tetrahydrogen triphosphate). Grades: ≥90% by AX-HPLC. Molecular formula: C10H18N3O14P3 (free acid). Mole weight: 497.18 (free acid).
5-Hydroxymethyl-dU-CE Phosphoramidite
5-Hydroxymethyl-dU-CE Phosphoramidite is an essential compound assuming a pivotal function in the development of pharmaceuticals oriented towards DNA modifications and epigenetic transformations. By contributing to the research and development of oligonucleotides and nucleic acid analogs, this distinctive compound facilitates the researchn of maladies encompassing cancer, genetic anomalies and viral infestations. Synonyms: 5'-Dimethoxytrityl-5-acetoxymethyl-2'-deoxyUridine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite. Grades: 95%. CAS No. 148380-57-8. Molecular formula: C42H51N4O10P. Mole weight: 802.86.
5-Hydroxymethylxylo-uridine
5-Hydroxymethylxylo-uridine is a potent biomedical compound widely utilized in the realm of neurology, exhibiting remarkable neuroprotective efficacy. Synonyms: 5-hydroxymethyl-1-β-D-xylofuranosyl-1H-pyrimidine-2,4-dione; 1-β-D-Xylofuranosyl-5-hydroxymethyl-uracil; 1-((2R,3R,4R,5R)-3,4-Dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-hydroxymethyl-1H-pyrimidine-2,4-dione; 1-[(2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-(hydroxymethyl)pyrimidine-2,4-dione; 5-(Hydroxymethyl)-1-(β-D-xylofuranosyl)-2,4(1H,3H)-pyrimidinedione. Grades: ≥95%. CAS No. 52448-09-6. Molecular formula: C10H14N2O7. Mole weight: 274.23.
5-hydroxyuridine
5-Hydroxyuridine is a uridine, a nucleoside; widely distributed in nature. Uridine is one of the four basic components of ribonucleic acid (RNA). Synonyms: Uridine, 5-hydroxy-; 1-(beta-D-ribofuranosyl)-5-hydroxypyrimidine-2,4(1H,3H)-dione; 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-hydroxy-pyrimidine-2,4-dione; 1-β-D-Ribofuranosylisobarbituric acid; Isobarbituridine. Grades: ≥95%. CAS No. 957-77-7. Molecular formula: C9H12N2O7. Mole weight: 260.20.
5-Indole-aa-2'-deoxyuridine
5-Indole-aa-2'-deoxyuridine, known for its prominent role in the biomedical sector, is an exceptional antiviral marvel. Its unparalleled efficacy against the DNA polymerase of herpes simplex virus type 1 (HSV-1) propels it to the forefront of HSV-1 infection treatment. Synonyms: 5-Indole-aa-dU. Grades: ≥97% by HPLC. Molecular formula: C23H26N4O6. Mole weight: 454.48.
5'-Inosinic Acid Disodium Salt Hydrate
5'-Inosinic Acid Disodium Salt Hydrate, a quintessential biochemical reagent employed in the pharmaceutical industry, has been deployed to cure a myriad of afflictions such as gout, arthritis and hyperuricemia while simultaneously doubling up as a flavor enhancer in the world of food and beverage. Synonyms: Disodium 5'-inosinate monohydrate. Grades: 97%. CAS No. 352195-40-5. Molecular formula: C10H13N4Na2O9P.xH2O. Mole weight: 410.18 (anhydrous).
5-Iodo-1-(2',3',5'-tri-O-acetyl-β-D-ribofuranosyl)-imidazo-4-carbonitrile is a compound useful in organic synthesis. Synonyms: [(2R,3R,4R,5R)-3,4-Diacetyloxy-5-(4-cyano-5-iodoimidazol-1-yl)oxolan-2-yl]methyl acetate; 5-Iodo-1-(2',3',5'-tri-O-acetyl-beta-D-ribofuranosyl)-imidazo-4-carbonitrile; 5-IODO-1-(2',3',5'-TRI-O-ACETYL-B-D-RIBOFURANOSYL)-IMIDAZO-4-CARBONITRILE;5-Iodo-1-(2',3',5'-tri-O-acetyl- beta -D-ribofuranosyl)-imidazo-4-carbonitrile; 5-Iodo-1-(2',3',5'-tri-O-acetyl-?-D-ribofuranosyl)-imidazo-4-carbonitrile; 5-Iodo-1-(2,3,5-tri-O-acetyl-beta-D-ribofuranosyl)-1H-imidazole-4-carbonitrile; 5-Iodo-1-(2 inverted exclamation mark ,3 inverted exclamation mark ,5 inverted exclamation mark -tri-O-acetyl-|A-D-ribofuranosyl)-imidazo-4-carbonitrile. CAS No. 59354-00-6. Molecular formula: C15H16IN3O7. Mole weight: 477.21.
5-Iodo-2'-C-methyluridine
5-Iodo-2'-C-methyluridine, renowned for its extraordinary biomedical capabilities, offering an innovative solution in research of viral infections. By impeding viral RNA research and development, this compound effectively hinders viral replication and subsequent dissemination. Synonyms: 5-Iodo-2'-C-methyl-1-β-D-ribofuranosyluracil; 1-((2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)-5-iodopyrimidine-2,4(1H,3H)-dione; 5-Iodo-2'-β-C-methyluridine. Grades: ≥95%. CAS No. 1203461-96-4. Molecular formula: C10H13IN2O6. Mole weight: 384.12.
5-Iodo-2'-O-methylcytidine
5-Iodo-2'-O-methylcytidine, a nucleoside analogue (NSA), is a chemotherapeutic agent that induces neuronal differentiation. Synonyms: Cytidine, 5-iodo-2'-O-methyl-; 4-Amino-1-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)-5-iodopyrimidin-2(1H)-one; 5-Iodo-2'-O-methyl-cytidine. Grades: ≥95%. CAS No. 847650-69-5. Molecular formula: C10H14IN3O5. Mole weight: 383.14.
5-Iodo-3'-deoxy-3'-fluorouridine
5-Iodo-3'-deoxy-3'-fluorouridine is an antineoplastic compound specifically impeding the growth and multiplication of malignant cells. Remarkably, it finds extensive application across a spectrum of cancers including breast cancer, liver cancer and leukemia. Synonyms: 5-iodo-1-[(2R,3S,4S,5R)-3-hydroxy-5-(hydroxymethyl)-4-fluorooxolan-2-yl]pyrimidine-2,4-dione. Grades: ≥95%. CAS No. 2072145-21-0. Molecular formula: C9H10FIN2O5. Mole weight: 372.09.
5'-Iodo-5'-deoxy Adenosine
Important precursors for the synthesis of nucleotides, sugar nucleosides and as biologically active substances. Uses: Important precursors for the synthesis of nucleotides, sugar nucleosides and as biologically active substances. Synonyms: 5'-Deoxy-5'-iodoadenosine; 5'-Iodo-5'-deoxyadenosine. Grades: 98%. CAS No. 4099-81-4. Molecular formula: C10H12IN5O3. Mole weight: 377.14.
5-Iodo-7-(2-C-methyl-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine is a remarkable biomedical compound, showcasing exceptional potential for studying numerous ailments. Its profound antiviral and antitumor effects emanate from its exquisite ability to intricately influence vital intracellular mechanisms. Synonyms: 4-Amino-5-iodo-7-(2-b-C-methyl-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine; (2R,3R,4R,5R)-2-(4-amino-5-iodo-pyrrolo[2,3-d]pyrimidin-7-yl)-5-(hydroxymethyl)-3-methyl-tetrahydrofuran-3,4-diol. Grades: ≥95%. CAS No. 847551-49-9. Molecular formula: C12H15IN4O4. Mole weight: 406.18.
5-Iodoarabinouridine
5-Iodoarabinouridine, a biomedical compound, displays remarkable potential for research of various diseases. Exerting its influence as an RNA research and development inhibitor, this compound takes center stage in the arena of cancer research. Its proficiency lies in the selective targeting of RNA molecules, effectively curbing the malignant growth and propagation of cancer cells. Synonyms: 1-(β-D-Arabinofuranosyl)-5-iodouracil; NSC 82221; I-araU; 2,4(1H,3H)-Pyrimidinedione, 1-beta-D-arabinofuranosyl-5-iodo-; 1-((2R,3S,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-iodopyrimidine-2,4(1H,3H)-dione; 1-beta-D-Arabinofuranosyl-5-iodouracil. Grades: ≥95%. CAS No. 3052-06-0. Molecular formula: C9H11IN2O6. Mole weight: 370.10.
5-Iodo-CDP
5-Iodo-CDP, a nucleotide analog utilized in experimental research and development for antiviral drugs, presents an inhibitory effect on a plethora of RNA viruses. From the notorious SARS-CoV to the insidious Lassa fever virus, this biomedicine product interferes with viral RNA synthesis and thereby suppresses viral replication. With its favorable outcomes in preclinical studies, this compound offers a considerable potential in the fight against viral infections. Synonyms: (5I-CDP); 5-Iodo-cytidine-5'-diphosphate, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C9H14N3O11P2I (free acid). Mole weight: 529.07 (free acid).
5-Iodo-CTP
5-Iodo-CTP is an indispensable constituent extensively utilized in the biomedical sector for investigative proceedings, representing a tailored rendition of Cytidine Triphosphate (CTP), harboring an iodine constituent. Esteemed for its distinct attributes, this particular compound finds vast utility in delving into nucleotide modifications and their consequential influence on cellular mechanisms. Synonyms: (5I-CTP); 5-Iodo-cytidine-5'-triphosphate, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C9H15N3O14P3I (free acid). Mole weight: 609.05 (free acid).
5-Iodo-cytidine
5-Iodo-cytidine, a potent nucleoside analog with antineoplastic properties, exhibits incredible efficacy in bladder cancer and leukemia treatment. By disturbing DNA synthesis, 5-Iodo-cytidine efficiently facilitates cell death. Its potential in halting cancer cell growth warrants further investigation. Grades: ≥ 98% by HPLC. Molecular formula: C9H12IN3O5. Mole weight: 369.11.
5-Iodo-dUTP
5-Iodo-dUTP is used in the synthesis of Texas Red-5-dUTP, a fluorescence-labelled nucleotide analog. Texas Red-5-dUTP is used diagnostically for detection of rearranged SS18 in formalin-fixed, paraffin-embedded synovial sarcoma. Synonyms: 5-Iodo-2'-deoxyuridine-5'-Triphosphate. Grades: ≥ 95% by HPLC. CAS No. 3731-55-3. Molecular formula: C9H14N2O14P3I (free acid). Mole weight: 594.04 (free acid).