BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
×
Product
Description
Suppliers Website
Apremilast-[d5]
Apremilast-[d5] is the labelled analogue of Apremilast. Apremilast is a selective inhibitor of phosphodiesterase 4 (PDE4) used as a drug for psoriasis and psoriatic arthritis. Synonyms: Apremilast D5; (S)-2-[1-(3-Ethoxy-d5-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione; (S)-N-(2-(1-(3-Ethoxy-d5-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide; Apremilast-d5. Grade: >95%. CAS No. 1258597-47-5. Molecular formula: C22H19D5N2O7S. Mole weight: 465.53.
Aprepitant-[d4]
Aprepitant-[d4] is the labelled analogue of Aprepitant. Aprepitant is a selective neurokinin-1 (NK-1) receptor antagonist used as an antiemetic agent. Synonyms: Aprepitant D4; 5-[[(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl-d4)-4-morpholinyl]methyl]-1,2-dihydro-3H-1,2,4-triazol-3-one; Emend-d4; MK 0869-d4; MK 869-d4. Grade: ≥97%; ≥98% atom D. CAS No. 1133387-60-6. Molecular formula: C23H17D4F7N4O3. Mole weight: 538.46.
Arachidic acid-[2,2-d2]
Arachidic acid-[2,2-d2]. Synonyms: Arachidic acid-2,2-d2; Eicosanoic-2,2-D2 acid. Grade: 98% atom D. CAS No. 232600-70-3. Molecular formula: C20H38D2O2. Mole weight: 314.54.
Arachidic acid-[d3]
Arachidic acid-[d3] is the labelled analogue of Arachidic acid, which is used for the production of detergents, photographic materials and lubricants. Synonyms: Arachidic acid (Methyl-D3); Eicosanoic-20,20,20-d3 Acid; Arachidic acid-d3; Eicosanoic acid-d3; Arachic acid-d3; icosanoic acid-d3; n-Eicosanoic acid-d3; Arachidinic acid-d3. Grade: 98% by CP; 99% atom D. CAS No. 202480-70-4. Molecular formula: C20H37D3O2. Mole weight: 315.55.
Arachidonic acid-[d8]
Arachidonic acid-[d8]. Synonyms: cis,cis,cis,cis-5,8,11,14-Eicosatetraenoic acid-5,6,8,9,11,12,14,15-d8; Arachidonic-5,6,8,9,11,12,14,15-d8 acid; Arachidonic acid-5,6,8,9,11,12,14,15-d8. Grade: 98% by CP; 98% atom D. CAS No. 69254-37-1. Molecular formula: C20H24D8O2. Mole weight: 312.52.
Arbidol hydrochloride
Arbidol is an antiviral agent used for the treatment of influenza infection in Russia and China. It has been used against influenza A and B viruses, and hepatitis C virus (HCV). It has been shown that ARB could inhibit COVID-19 infection through interfering the release of SARS-CoV-2 from intracellular vesicles. It can be used to treat trypanosomiasis in livestock. Synonyms: Arbidol HCl; Umifenovir hydrochloride; 6-Bromo-4-[(dimethylamino)methyl]-5-hydroxy-1-methyl-2-[(phenylthio)methyl]-1H-indole-3-carboxylic Acid Ethyl Ester Hydrochloride. Grade: >98%. CAS No. 131707-23-8. Molecular formula: C22H26BrClN2O3S. Mole weight: 513.88.
Arbutin-[13C6]
Arbutin-[13C6] is the labelled analogue of Arbutin, a glycosylated hydroquinone that can be extracted from bearberry plant. Arbutin is a known inhibitor of tyrosinase, which in turn prevents the formation of melanin. Arbutin is often used as a skin-lightening agent in cosmetic products. Synonyms: Arbutin-13C6; 4-Hydroxyphenyl-β-D-glucopyranoside-13C6; Arbutine-13C6; Arbutoside-13C6; Arbutyne-13C6; Hydroquinone Glucose-13C6; Hydroquinone β-D-Glucopyranoside-13C6; NSC 4036-13C6; Ursin-13C6; Uvasol-13C6; p-Arbutin-13C6; p-Hydroxyphenyl β-D-Glucopyranoside-13C6; p-Hydroxyphenyl β-D-Glucoside-13C6; β-Arbutin-13C6. Grade: >95%. Molecular formula: C6[13C]6H16O7. Mole weight: 278.21.
Argatroban-[d3]
Argatroban-[d3] is the labelled analogue of Argatroban. Argatroban is a direct thrombin inhibitor used as an anticoagulant. Synonyms: Argatroban D3; (2R,4R)-1-[(2S)-5-[(Aminoiminomethyl)amino]-1-oxo-2-[[(1,2,3,4-tetrahydro-3-(methyl-d3)-8-quinolinyl)sulfonyl]amino]pentyl]-4-methyl-2-piperidinecarboxylic Acid; Argipidine-d3; MQPA-d3. Grade: >95%. CAS No. 1356847-56-7. Molecular formula: C23H33D3N6O5S. Mole weight: 511.66.
Aripiprazole
Aripiprazole binds with high affinity to both the G protein-coupled and uncoupled states of receptors. Aripiprazole potently activates D2 receptor-mediated inhibition of cAMP accumulation. Synonyms: OPC-14597; OPC 14597; OPC14597; Abilify; Abilitat; Abilify Discmelt. Grade: >98%. CAS No. 129722-12-9. Molecular formula: C23H27Cl2N3O2. Mole weight: 448.39.
Aripiprazole-[butyl-d8]
Aripiprazole-[d8] is a labelled analogue of Aripiprazole. Aripiprazole is an atypical antipsychotic. Synonyms: Aripiprazole-(butoxy-D8); Aripiprazole-d8; 2(1H)-Quinolinone, 7-[4-[4-(2,3-dichlorophenyl)-1-piperazinyl]butoxy-1,1,2,2,3,3,4,4-d8]-3,4-dihydro-; 7-[4-[4-(2,3-Dichlorophenyl)-1-piperazinyl]butoxy-1,1,2,2,3,3,4,4-d8]-3,4-dihydro-2(1H)-quinolinone; Aripiprazole-d8 (Butyl-d8). Grade: 98% by CP; 98% atom D. CAS No. 1089115-04-7. Molecular formula: C23H19D8Cl2N3O2. Mole weight: 456.43.
Aripiprazole-[d8]
Aripiprazole-[d8] is the labelled analogue of Aripiprazole. Aripiprazole, a dihydroquinolinone derivative, is an antagonist of Dopamine-2 receptor and a partial agonist of 5-HT1A receptor. It could be used as an atypical antipsychotic agent. Uses: An isotopic labelled form of aripiprazole which is an antagonist of dopamine-2 receptor and a partial agonist of 5-ht1a receptor that could be used as an antipsychotic agent. Synonyms: Aripiprazole D8; 7-[4-[4-(2,3-Dichlorophenyl)-1-piperazinyl-d8]butoxy]-3,4-dihydro-2(1H)-quinolinone; 7-[4-[4-(2,3-Dichlorophenyl)-1-piperazinyl-d8]butoxy]-3,4-dihydrocarbostyril; Abilify-d8; Abilitat-d8; Aripiprazole-d8; OPC 14597-d8; 2(1H)?-Quinolinone, 7-[4-[4-(2,?3-dichlorophenyl)?-1-piperazinyl-2,?2,?3,?3,?5,?5,?6,?6-d8]?butoxy]?-3,?4-dihydro-. Grade: 97%; ≥97% atom D. CAS No. 1089115-06-9. Molecular formula: C23H19D8Cl2N3O2. Mole weight: 456.43.
Artemether
Artemether is an antimalarial for the treatment of multiple drug-resistant strains of Plasmodium falciparum malaria. Synonyms: Dihydroartemisinin Methyl Ether; Falcidol; Gvither; Larither; Malartem; SM 224; β-Artemether; β-Dihydroartemisinin Methyl Ether; (3R,5aS,6R,8aS,9R,10S,12R,12aR)-Decahydro-10-methoxy-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin. Grade: >99%. CAS No. 71963-77-4. Molecular formula: C16H26O5. Mole weight: 298.37.
Artemether-[13C,d3]
Artemether-[13C,d3] is the labelled analogue of Artemether. Artemether is an antimalarial for the treatment of multiple drug-resistant strains of Plasmodium falciparum malaria. Synonyms: (3R,5aS,6R,8aS,9R,10S,12R,12aR)-10-(Methoxy-13C-d3)-3,6,9-trimethyldecahydro-12H-3,12-epoxy[1,2]dioxepino[4,3-i]isochromene; Artemether-13C,D3; Artemether 13C D3; (3R,5aS,6R,8aS,9R,10S,12R,12aR)-Decahydro-10-methoxy-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-13C,d3; Artemos-13C,d3; Artenam-13C,d3; Artesaph-13C,d3; Artesian-13C,d3; Dihydroartemisinin Methyl Ether-13C,d3; Falcidol-13C,d3; Gvither-13C,d3; Larither-13C,d3; Malartem-13C,d3; β-Artemether-13C,d3; β-Dihydroartemisinin Methyl Ether-13C,d3. Grade: 95% by HPLC; 98% atom 13C; 98% atom D. Molecular formula: C15[13C]H23D3O5. Mole weight: 302.39.
Artemether-[d3]
Artemether-[d3] is the labelled analogue of Artemether. Artemether is an antimalarial for the treatment of multiple drug-resistant strains of Plasmodium falciparum malaria. Synonyms: Artemether-d3; Falcidol-d3; Larither-d3; [2H3]-beta-Dihydroartemisinin methyl ether; Malartem-d3; Artesian-d3; β-Artemether-d3; (3R,5aS,6R,8aS,9R,10S,12R,12aR)-Decahydro-10-(methoxy-d3)-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin; Decahydro-10-(methoxy-d3)-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin; Artemos-d3; Dihydroartemisinin-d3 Methyl Ether. Grade: 98%; 98% atom D. CAS No. 93787-85-0. Molecular formula: C16H23D3O5. Mole weight: 301.39.
Artemisinin-[d3]
Artemisinin-[d3] is the labelled analogue of Artemisinin. Artemisinin is a natural product originally isolated from plants of the genus Artemisia. It effectively kills malarial parasites of the genus Plasmodium. It is usually used in combination therapy for the treatment of malaria. Artemisinin is also used against a wide range of trematodes, including Schistosoma. Synonyms: Artemisinin D3; (3R,5aS,6R,8aS,9R,12S,12aR)-Octahydro-3,6-dimethyl-9-(methyl-d3)-3,12-epox-12H-pyrano[4,3-j]-1,2-benzodioxepin-10(3H)-one; Artemisine-d3; Arteannuin-d3; Huanghuahaosu-d3; QHS-d3. Grade: 98% by HPLC; ≥99% atom D. CAS No. 176652-07-6. Molecular formula: C15H19D3O5. Mole weight: 285.36.
Artesunate-[d3]
Artesunate-[d3] is the labelled analogue of Artesunate. Artesunate is a derivative of the natural product Artemisinin and a medication used for the treatment of malaria. Synonyms: 4-(((3R,5aS,6R,8aS,9R,10S,12R,12aR)-3,6-Dimethyl-9-(methyl-d3)decahydro-12H-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10-yl)oxy)-4-oxobutanoic acid; Artesunate-D3; Artesunate-d3; Butanedioic acid, mono[(3R,5aS,6R,8aS,9R,10S,12R,12aR)-decahydro-3,6-dimethyl-9-(methyl-d3)-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-yl] ester; Artesunic acid-d3. Grade: >95%. CAS No. 1316303-44-2. Molecular formula: C19H25D3O8. Mole weight: 387.44.
Artesunate-d4
Artesunate-[d4] is the labelled analogue of Artesunate. Artesunate is a derivative of the natural product Artemisinin and a medication used for the treatment of malaria. Synonyms: Artesunate-d4; Butanedioic Acid Mono(3R,5aS,6R,8aS,9R,10R,12R,12aR)-decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-yl] Ester-d4; Artesunic Acid-d4; 4-oxo-4-(((3R,5aS,6R,8aS,9R,10S,12R,12aR)-3,6,9-trimethyldecahydro-12H-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10-yl)oxy)butanoic-2,2,3,3-d4 acid. Grade: ≥97%; ≥97% atom D. CAS No. 1316753-15-7. Molecular formula: C19H24D4O8. Mole weight: 388.45.
(-)-AS 115
(-)-AS 115, an isomer of AS 115, is a potent and selective inactivator of KIAA1363. KIAA1363 is an enzyme that catalyzes the hydrolysis of the 2-acetyl MAGE to MAGE and serves as a central enzyme in the PAF and LPA signaling network. Synonyms: (-)-AS 115; CHEMBL2069333; ()-AS 115; 2-Fluorophenyl-(2-(((1R,2S)-2-(butoxymethyl)cyclohexyl)methoxy)ethyl)carbamate; AS 115; AS115; BDBM50390508. Grade: ≥98%. CAS No. 926657-43-4. Molecular formula: C21H32FNO4. Mole weight: 381.5.
Asenapine-[13C,d3]
Asenapine-[13C,d3] is the labelled analogue of Asenapine, which is a combined serotonin (5HT2) and dopamine (D2) receptor antagonist used for the treatment of schizophrenia atypical antipsychotic drugs. Synonyms: Asenapine-13C,d3; (3aR,12bR)-rel-5-Chloro-2,3,3a,12b-tetrahydro-2-(methyl-13C,d3)-1H-dibenz[2,3:6,7]oxepino[4,5-c]pyrrole; trans-5-Chloro-2,3,3a,12b-tetrahydro-2-(methyl-13C,d3)-1H-dibenz[2,3:6,7]oxepino[4,5-c]pyrrole. Grade: ≥96% by HPLC; ≥96% atom 13C; ≥96% atom D. CAS No. 1217729-73-1. Molecular formula: C16[13C]H13D3ClNO. Mole weight: 289.78.
Aspartame-[d5]
Aspartame-[d5] is the labelled analogue of Aspartame. Aspartame is an artificial, non-saccharide sweetener used as a sugar substitute in some foods and beverages. Synonyms: Aspartame D5; L-α-Aspartyl-L-phenylalanine 2-(Methyl-d5) Ester; Canderel-d5; Dipeptide-d5 Sweetener; Equal-d5; Finn-d5; L-Aspartame-d5; NutraSweet-d5; Pal Sweet-d5; Palsweet Diet-d5; Sweet Dipeptide-d5; Zero-Cal-d5; α-Aspartame-d5; α-L-Aspartyl-L-phenylalanine (Methyl-d5) Ester; α-Sweet-d5. Grade: ≥95%; ≥97% atom D. CAS No. 1356849-17-6. Molecular formula: C14H13D5N2O5. Mole weight: 299.34.
Aspirin
Aspirin is a salicylate and irreversible COX1 and COX2 inhibitor. It can be used for the treatment of fever, rheumatism, nerve, muscle, joint pain, soft tissue inflammation and gout in animals. Synonyms: Acetylsalicylic acid. Grade: 99.5%. CAS No. 50-78-2. Molecular formula: C9H8O4. Mole weight: 180.16.
Aspirin Impurity
A metabolite of Acetylsalicylic Acid. Synonyms: 2-(2,4-Dihydroxybenzoyl)benzoic Acid. Grade: > 95%. CAS No. 2513-33-9. Molecular formula: C14H10O5. Mole weight: 258.23.
Astemizole-[d3]
Astemizole-[d3] is the labelled analogue of Astemizole, which is a nonsedating-type histamine H1-receptor antagonist. Potential for combination therapy with anticancer drugs such as doxorubicin in resistant leukemia. Antihistaminic. Synonyms: Astemizole D3; 1-[(4-Fluorophenyl)methyl]-N-[1-[2-(4-methoxy-d3-phenyl)ethyl]-4-piperidinyl]-1H-benzimidazol-2-amine; Astemisan-d3; Hismanal-d3; Histamen-d3; Paralergin-d3; Retolen-d3; Waruzol-d3. Grade: ≥95%; ≥99% atom D. CAS No. 1189961-39-4. Molecular formula: C28H28D3FN4O. Mole weight: 461.59.
Ataluren-[d4]
Ataluren-[d4] is a labelled Ataluren. Ataluren is a medication used for the treatment of Duchenne muscular dystrophynonsense caused by nonsense mutation (nmDMD). Synonyms: 3-(5-(2-Fluorophenyl-3,4,5,6-d4)-1,2,4-oxadiazol-3-yl)benzoic acid; Ataluren-D4; 3-[5-(6-Fluorophenyl-2,3,4,5-d4)-1,2,4-oxadiazol-3-yl]benzoic acid; PTC124-d4. Grade: >95%. CAS No. 1922064-61-6. Molecular formula: C15H5D4FN2O3. Mole weight: 288.27.
Atazanavir-[d6]
Atazanavir-[d6] is the labelled analogue of Atazanavir. Atazanavir is a novel and potent azapeptide protease inhibitor that specifically inhibits the human immunodeficiency virus type 1 (HIV-1) protease enzyme with inhibition constant Ki of 66 nmol/L and also inhibits the viral replication of HIV-1 with 50% effective concentration EC50 ranging from 2.6 to 5.3 nmol/L. Atazanavir binds to HIV-1 protease preventing the cleavage of gag and gag-pol polyproteins, which results in the formation of immature virions in HIV-1-infected cells. Atazanavir has a different C-2 symmetric chemical structure and a generally greater antiretroviral potency in various HIV strains compared to other protease inhibitors, including indinavir, nelfinavir, ritonavir, saquinavir and amprenavir. Synonyms: Atazanavir D6; (3S,8S,9S,12S)-12-Bis(1,1-dimethylethyl)-8-hydroxy-4,11-dioxo-9-(phenylmethyl)-6-[[4-(2-pyridinyl)phenyl]methyl]-2,5,6,10,13-Pentaazatetradecanedioic Acid 14-di(methyl-d3) Ester. Grade: ≥98%; ≥99% atom D. CAS No. 1092540-50-5. Molecular formula: C38H46D6N6O7. Mole weight: 710.89.
Atenolol-[d7]
Atenolol-[d7] is the labelled analogue of Atenolol, which is a selective Cardioselective β-adrenergic blocker. Synonyms: Atenolol-d7; 4-[2-Hydroxy-3-[(1-methylethyl-d7)amino]propoxyl]benzeneacetamide; 2-[p-[2-Hydroxy-3-(isopropylamino-d7)propoxy]phenyl]acetamide; (RS)-Atenolol-d7; (+/-)-Atenolol-d7; Atehexal-d7; Atenol-d7; Cuxanorm-d7; Myocord-d7; Normalol-d7; Normiten-d7; Uniloc-d7; Vericordin-d7; Wesipin-d7; Xaten-d7; dl-Atenolol-d7. Grade: ≥95%; ≥99% atom D. CAS No. 1202864-50-3. Molecular formula: C14H15D7N2O3. Mole weight: 273.39.
Atomoxetine-[d3] hydrochloride
Atomoxetine-[d3] hydrochloride is the labelled salt of Atomoxetine. Atomoxetine is a norepinephrine (noradrenaline) reuptake inhibitor used to treat attention-deficit hyperactivity disorder (ADHD). Synonyms: Atomoxetine hydrochloride D3; (R)-N-(Methyl-d3)-γ-(2-methylphenoxy)-benzenepropanamine hydrochloride; Atomoxetine-d3 Hydrochloride; (R)-N-(Methyl-d3)-(2-methylphenoxy)benzenepropanamine Hydrochloride; R-Tomexetine-d3 Hydrochloride; Tomoxetine-d3 Hydrochloride; LY 139603-d3; Strattera-d3. Grade: 98% by HPLC; ≥99% atom D. CAS No. 1217776-38-9. Molecular formula: C17H18D3NO.HCl. Mole weight: 294.83.
Atomoxetine-[d5] hydrochloride
Atomoxetine-[d5] hydrochloride is the labelled salt of Atomoxetine. Atomoxetine is a norepinephrine (noradrenaline) reuptake inhibitor used to treat attention-deficit hyperactivity disorder (ADHD). Synonyms: rac Atomoxetine-d5 Hydrochloride; Tomoxetine-d5 hydrochloride; LY 139603-d5; (R)-Tomoxetine-d5 hydrochloride. Grade: 95% by HPLC; 98% atom D. CAS No. 1398065-95-6. Molecular formula: C17H17D5ClNO. Mole weight: 296.85.
Atorvastatin Acetonide Tert-Butyl Ester-[d5]
Atorvastatin Acetonide Tert-Butyl Ester-[d5] is the labelled analogue of Atorvastatin Acetonide Tert-Butyl Ester, which is the intermediate of Atorvastatin. Uses: An deuterated intermediate of deuterated atorvastatin, a selective, competitive hmg-coa reductase inhibitor. the only drug in its class specfically indicated for lowering both elevated ldl-cholesterol and triglycerides in patients with hypercholesterolem. Synonyms: Atorvastatin Acetonide Tert-Butyl Ester-d5. Grade: 95% atom D. CAS No. 265989-34-2. Molecular formula: C40H42D5FN2O5. Mole weight: 659.84.
Atorvastatin calcium
Atorvastatin Calcium is an inhibitor of HMG-CoA reductase used as a cholesterol-lowering medication that blocks the production of cholesterol. Grade: >98%. CAS No. 134523-03-8. Molecular formula: 2(C33H34FN2O5).Ca. Mole weight: 1155.34.
Atorvastatin-[d5] Calcium Salt
Atorvastatin-[d5] Calcium Salt is the labelled analogue of Atorvastatin Calcium Salt, which is a selective, competitive inhibitor of HMG-CoA reductase. Synonyms: Atorvastatin D5 calcium; (βR,δR)-2-(4-Fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-(phenyl-d5)-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic Acid Calcium Salt (2:1); Atorvastatin-d5 Hemicalcium; di(Atorvastatin-d5) Calcium Salt. Grade: ≥97% by HPLC; ≥99% atom D. CAS No. 222412-82-0. Molecular formula: (C33H29D5FN2O5)2.Ca. Mole weight: 1165.42.
Atorvastatin Lactone-[d5]
Atorvastatin Lactone-[d5] is a labelled intermediate of Atorvastatin which is an inhibitor of MAP kinase and HMG-CoA reductase for the treatment of inflammation. Synonyms: 5-(4-fluorophenyl)-1-{2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl}-4-(2H5)phenyl-N-phenyl-2-(propan-2-yl)-1H-pyrrole-3-carboxamide; CS-P-07047; Atorvastatin-d5 Lactone. Grade: > 95%. CAS No. 1217749-86-4. Molecular formula: C33H28D5FN2O4. Mole weight: 545.65.
Atovaquone-[d4]
Atovaquone-[d4] is a labelled Atovaquone. Atovaquone is a chemical compound with therapeutic effect against pneumocystis pneumonia (PCP), malaria, babesia, etc. Synonyms: 2-[trans-4-(4-Chlorophenyl-d4)cyclohexyl-]-3-hydroxy-1,4-naphthalenedione; 566C80-d4; BW-566C-d4; BW-566C-80-d4; Mepron-d4; Wellvone-d4. Grade: 98.5% HPLC; 98% atom D. CAS No. 2070015-14-2. Molecular formula: C22H15DClO3. Mole weight: 370.87.
Atrazine-[15N]
Atrazine-[15N] is the labelled analogue of Atrazine. Synonyms: Atrazine-(ethylamino-15N); 2-Chloro-4-ethylamino-15N-6-isopropylamino-1,3,5-triazine. Grade: 98% by CP; 99% atom 15N. CAS No. 287476-17-9. Molecular formula: C8H14ClN4[15N]. Mole weight: 216.68.
Atrazine-[d5]
Atrazine-[d5] is the labelled analogue of Atrazine, which is a selective herbicide. Synonyms: Atrazine-d5; 6-Chloro-N-(ethyl-d5)-N'-(1-methylethyl)-1,3,5-triazine-2,4-diamine; 2-Chloro-4-(ethylamino-d5)-6-(2-propylamino)-s-triazine; Gesamprim-d5. Grade: ≥97%; ≥98% atom D. CAS No. 163165-75-1. Molecular formula: C8H9D5ClN5. Mole weight: 220.72.
Atrazine-[d7]
Atrazine-[d7] is the labelled analogue of Atrazine, which is a selective herbicide. Synonyms: Atrazine-D7; 6-Chloro-N-ethyl-N'-isopropyl-D7-[1,3,5]triazine-2,4-diamin; Gesaprim-d7; Atrazin-d7; Chromozin-d7; Oleogesaprim-d7; Aktikon-d7; Argezin-d7. Grade: 95% by HPLC; 98% atom D. Molecular formula: C8H7D7ClN5. Mole weight: 222.73.
Atrazine-desethyl-[d7]
Atrazine-desethyl-[d7] is the labelled analogue of Atrazine-desethyl, which has been shown to inhibit the growth of plants. Synonyms: 6-Chloro-N-isopropyl-D7-1,3,5-triazine-2,4-diamine; Atrazine-desethyl-D7; 2-Amino-4-(isopropyl-d7-amino)-6-chloro-triazine; Desethylatrazine-d7. Grade: ≥97% by HPLC; ≥99% atom D. CAS No. 1216649-31-8. Molecular formula: C6H3D7ClN5. Mole weight: 194.67.
Atreleuton-[d4]
Atreleuton-[d4] is a labelled Atreleuton. Atreleuton is a 5-lipoxygenase inhibitor that has the potential to treat acute coronary syndrome. Synonyms: (2R)-4-(5-{[4-fluoro(2H4)phenyl]methyl}thiophen-2-yl)-N-hydroxy-N-(C-hydroxycarbonimidoyl)but-3-yn-2-amine. Grade: 95% by HPLC; 98% atom D. Molecular formula: C16H11D4FN2O2S. Mole weight: 322.39.
Atropine
Atropine is an alkaloid as an nerve agent that occurs naturally in plants of the nightshade family. Uses: Used as a pesticide poisoning and as a muscle relaxant when injected intravenously. Synonyms: (8-methyl-8-azabicyclo[3.2.1]octan-3-yl) 3-hydroxy-2-phenylpropanoate; L-Hyoscyamine; Hyoscyamine. Grade: ≥98%. CAS No. 51-55-8. Molecular formula: C17H23NO3. Mole weight: 289.37.
Auristatin E
Auristatin E is a synthetic analog of dolastatin 10. Auristatin E is a highly potent antimitotic agent.Auristatin E inhibits tubulin polymerization. Auristatin E is a cytotoxic tubulin modifier with potent and selective antitumor activity. Uses: Adcs cytotoxin. Synonyms: Auristatin E. Grade: ≥96.0% (HPLC). CAS No. 160800-57-7. Molecular formula: C40H69N5O7. Mole weight: 732.01.
Avanafil
A phosphodiesterase (PDE5) inhibitor, used to treat erectile dysfunction. Synonyms: TA-1790; TA 1790; TA1790; Avanafil; trade name: Stendra; Spedra. Grade: 99%. CAS No. 330784-47-9. Molecular formula: C23H26ClN7O3. Mole weight: 483.95064.
Avicularin
Avicularin, a natural plant flavonoid isolated from the herbs of Polygonum aviculare, exhibits anti-inflammatory activity through the suppression of ERK signaling pathway in LPS-stimulated RAW 264.7 macrophage cells. By decreasing C/EBPα-activated GLUT4-mediated glucose uptake in adipocytes and potently inhibiting fatty acid synthase, avicularin can inhibit the accumulation of the intracellular lipids. Uses: Anti-inflammatory. Synonyms: Fenicularin; Quercetin 3-alpha-L-arabinofuranoside; Avicularoside. Grade: >98%. CAS No. 572-30-5. Molecular formula: C20H18O11. Mole weight: 434.4.
Axitinib
Axitinib (AG013736) is a tyrosine kinase inhibitor developed by Pfizer. Axitinib is a tyrosine kinase inhibitor that blocks the activation of VEGFR1, VEGFR2, VEGFR3, c-kit, and PDGFRβ (IC50 = 1.2, 0.25, 0.29, 1.7, and 1.6 nM, respectively). It has been shown to significantly inhibit growth of breast cancer in animal (xenograft) models. Uses: Protein kinase inhibitors. Synonyms: AG 013736; N-methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]-benzamide; Inlyta. Grade: ≥98%. CAS No. 319460-85-0. Molecular formula: C22H18N4OS. Mole weight: 386.5.
Axitinib-[13C,d3]
Axitinib-[13C,d3] is a labelled Axitinib. Axitinib is a tyrosine kinase inhibitor that blocks the activation of VEGFR1, VEGFR2, VEGFR3, c-kit, and PDGFRβ (IC50 = 1.2, 0.25, 0.29, 1.7, and 1.6 nM, respectively). It has been shown to significantly inhibit growth of breast cancer in animal (xenograft) models. Synonyms: [13C,2H3]-N-Methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]benzamide; (E)-N-(methyl-13C-d3)-2-((3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)benzamide. Grade: > 98%. CAS No. 1261432-00-1. Molecular formula: C21[13C]H15D3N4OS. Mole weight: 390.48.
Axitinib-[d3]
Axitinib-[d3] is the labelled analogue of Axitinib. Axitinib is a tyrosine kinase inhibitor that blocks the activation of VEGFR1, VEGFR2, VEGFR3, c-kit, and PDGFRβ (IC50 = 1.2, 0.25, 0.29, 1.7, and 1.6 nM, respectively). It has been shown to significantly inhibit growth of breast cancer in animal (xenograft) models. Synonyms: Axitinib D3; N-(Methyl-d3)-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]benzamide; AG 013736-d3; Axitinib-d3 (N-methyl-d3). Grade: 95% by HPLC; 98% atom D. CAS No. 1126623-89-9. Molecular formula: C22H15D3N4OS. Mole weight: 389.49.
Azamethiphos-[d6]
Azamethiphos-[d6]. Uses: Synergistic insecticidal and acaricidal organophosphorus compound. Synonyms: Azamethiphos D6; S-[(6-Chloro-2-oxooxazolo[4,5-b]pyridin-3(2H)-yl)methyl] O,O-Dimethyl-d6 Ester Phosphorothioic Acid; Azametiphos-d6; CGA 18809-d6; Ciba-Geigy 18809-d6; Salmosan-d6; Snip-d6. Grade: ≥99%; ≥99% atom D. CAS No. 1189894-02-7. Molecular formula: C9H4D6ClN2O5PS. Mole weight: 330.71.
Azaperol-[d4]
Azaperol-[d4] is a labelled Azaperol, which is a metabolite of azaperone. Synonyms: 1-(4-Fluorophenyl-D4)-4-(4-pyridin-2-yl-piperazin-1-yl)-butan-1-ol. Grade: 95% by HPLC; 98% atom D. Molecular formula: C19H20D4FN3O. Mole weight: 333.44.
Azaperone-[d4]
Azaperone-[d4] is the labelled analogue of Azaperone, which is a pyridinylpiperazine and butyrophenone neuroleptic drug with sedative and antiemetic effects. It is mainly used as a tranquilizer in veterinary medicine. Synonyms: Azaperone-D4; 1-(4-Fluorophenyl-D4)-4-(4-pyridin-2-yl-piperazin-1-yl)-butan-1-one; 1-(4-Fluorophenyl)-4-[4-(2-pyridinyl)-1-piperazinyl]-1-butanone-d4; 4'-Fluoro-4-[4-(2-pyridyl)-1-piperazinyl]butyrophenone-d4; Fluoperidol-d4; NSC 170976-d4; Stresnil-d4; Suicalm-d4. Grade: 95% by HPLC; 98% atom D. CAS No. 1173021-72-1. Molecular formula: C19H18D4FN3O. Mole weight: 331.42.
Azasetron-[d3] Hydrochloride
Azasetron-[d3] Hydrochloride is the labelled analogue of Azasetron Hydrochloride, which is a 5-HT3 receptor antagonist and used as an antiemetic. Synonyms: Azasetron-d3 Hydrochloride; N-1-Azabicyclo[2.2.2]-oct-3-yl-6-chloro-3,4-dihydro-4-(methyl-d3)-3-oxo-2H-1,4-benzoxazine-8-carboxamide Hydrochloride; Serotone-d3; Nazasetron-d3; Y-25130-d3 hydrochloride; 6-chloro-4-methyl-3-oxo-N-(quinuclidin-3-yl)-3,4-dihydro-2H-benzo[b][1,4]oxazine-8-carboxamide-d3 hydrochloride. Grade: 98%; ≥99% atom D. CAS No. 1216505-58-6. Molecular formula: C17H18D3Cl2N3O3. Mole weight: 389.29.
(-)-Azasetron hydrochloride
The (-)-enantiomer of Azasetron hydrochloride, which is a selective 5-HT3 antagonist. Grade: 99%. CAS No. 123040-96-0. Molecular formula: C17H20ClN3O3.HCl. Mole weight: 386.27.
(+)-Azasetron hydrochloride
The (+)-enantiomer of Azasetron hydrochloride, which is a selective 5-HT3 antagonist. Uses: Antiemetics. Synonyms: azasetron hydrochloride; 123040-16-4; Azasetron HCl; 123040-69-7; Serotone; Y-25130 hydrochloride; 141922-90-9; Azasetron (hydrochloride); AZASETRONHYDROCHLORIDE; Azasetron hydrochloride [JAN]; D-erythro-Sphingosine (Brain, Porcine); 123040-93-7; 477243-03-1; 123040-96-0; 2BSS7XL60S; 123040-94-8; Y-25130 HCl; 2H-1,4-Benzoxazine-8-carboxamide, N-1-azabicyclo[2.2.2]oct-3-yl-6-chloro-3,4-dihydro-4-me. Grade: 99%. CAS No. 123040-94-8. Molecular formula: C17H20ClN3O3.HCl. Mole weight: 386.27.
Azathioprine
Azathioprine is an immunosuppressive drug, inhibiting purine synthesis and GTP-binding protein Rac1 activation, used in the treatment of organ transplantation and autoimmune diseases. Uses: Antimetabolites. Synonyms: azathioprine; 446-86-6; Imuran; Azothioprine; Azathioprin; Azamun; Azanin; Azatioprin; Azasan; Ccucol; Imurek; Imurel; Muran; Azathiopurine; Rorasul; Azathioprinum; BW 57-322; NSC-39084; BW-57-322; Azatioprina; 6-(1-Methyl-4-nitroimidazol-5-yl)thiopurine; NCI-C03474; NSC 39084; Methylnitroimidazolylmercaptopurine; 6-(1-Methyl-p-nitro-5-imidazolyl)-thiopurine; Azathioprinum [INN-Latin]; Azatioprina [INN-Spanish]; CCRIS 62; Imuran (TN); 6-((1-Methyl-4-nitro-1H-imidazol-5-yl)thio)-1H-purine; 6-[(1-methyl-4-nitro-1H-imidazol-5-yl)sulfanyl]-7H-purine; 6-(1'-Methyl-4'-nitro-5'-imidazolyl)-mercaptopurine; HSDB 7084; 6-((1-Methyl-4-nitroimidazol-5-yl)thio)purine; Purine, 6-(1-methyl-4-nitro-5-imidazolylthio)-; 1H-Purine, 6-((1-methyl-4-nitro-1H-imidazol-5-yl)thio)-. Grade: >98%. CAS No. 446-86-6. Molecular formula: C9H7N7O2S. Mole weight: 277.26.
Azathioprine-[13C4]
Azathioprine-[13C4] is the labelled analogue of Azathioprine. Azathioprine is an immunosuppressive drug, inhibiting purine synthesis and GTP-binding protein Rac1 activation, used in the treatment of organ transplantation and autoimmune diseases. Synonyms: Azathioprine-13C4; 6-[(1-Methyl-4-nitro-1H-imidazol-5-yl)thio]-1H-purine-13C4; BW-57-322-13C4; NSC-39084-13C4; Azanin-13C4; Imuran-13C4; Imurek-13C4; Imurel-13C4; Zytrim-13C4. Grade: ≥96%; ≥98% atom 13C. CAS No. 1346600-71-2. Molecular formula: C5[13C]4H7N7O2S. Mole weight: 281.23.
Azelastine-[d4] Hydrochloride
Azelastine-[d4] HCl is a labelled analogue of Azelastine. Azelastine is a histamine-H1-receptor antagonist used for the treatment of nasal diseases such as rhinitis. Synonyms: 4-(4-Chlorobenzyl)-2-(1-methylazepan-4-yl)phthalazin-1(2H)-one-5,6,7,8-d4 hydrochloride. Grade: 95% by HPLC; 98% atom D. Molecular formula: C22H21D4Cl2N3O. Mole weight: 422.38.
Azelnidipine-[d7]
Azelnidipine-[d7] is the labelled analogue of Aznidipine, which is a dihydropyridine calcium channel blocker with antihypertensive activity. Aznidipine is used to treat ischemic heart disease and cardiac remodeling after myocardial infarction. Synonyms: Azelnidipine D7; (±)-2-Amino-1,4-dihydro-6-methyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid 3-[1-(Diphenylmethyl)-3-azetidinyl] 5-(1-methylethyl) Ester-d7; Azelnidipine-d7; CS 905-d7. Grade: >98%. CAS No. 2070015-18-6. Molecular formula: C33H27D7N4O6. Mole weight: 589.69.
Azilsartan
Azilsartan (TAK-536) is an angiotensin II receptor antagonist used in the treatment of hypertension. Synonyms: TAK-536; TAK 536; TAK536. Grade: 0.98. CAS No. 147403-03-0. Molecular formula: C25H20N4O5. Mole weight: 456.46.
Azilsartan-[d4]
Azilsartan-[d4] is the labelled analogue of Azilsartan. Azilsartan is an angiotensin II receptor antagonist used for the treatment of hypertension in adults. Synonyms: Azilsartan D4; 1-[[2'-(2,5-Dihydro-5-oxo-1,2,4-oxadiazol-3-yl)[1,1'-biphenyl]-4-yl]methyl]-2-ethoxy-1H-benzimidazole-7-carboxylic Acid-d4; 2-Ethoxy-1-[[2'-(4,5-dihydro-5-oxo-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]methyl]benzimidazole-7-carboxylic Acid-d4; TAK 536-d4; Azilsartan para-Phenylene-d4. Grade: >95%. CAS No. 1794817-45-0. Molecular formula: C25H16D4N4O5. Mole weight: 460.47.
Azilsartan-[d5]
Azilsartan-[d5] is the labelled analogue of Azilsartan, which is an angiotensin II type 1 receptor antagonist and could be used against hypertension and inflammation. Synonyms: Azilsartan D5; 1-[[2'-(2,5-Dihydro-5-oxo-1,2,4-oxadiazol-3-yl)[1,1'-biphenyl]-4-yl]methyl]-2-(ethoxy-d5)-1H-benzimidazole-7-carboxylic Acid; 2-(Ethoxy-d5)-1-[[2'-(4,5-dihydro-5-oxo-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]methyl]benzimidazole-7-carboxylic Acid; TAK 536-d5; Azilsartan O-Ethyl-d5. Grade: ≥98% by HPLC; ≥99% atom D. CAS No. 1346599-45-8. Molecular formula: C25H15D5N4O5. Mole weight: 461.48.
Azithromycin-[6-methyl-13C,d3]
One of the isotopic labelled form of Azithromycin, which is an azalide macrolide antibiotic. Synonyms: Azithromycin-13CD3; Azithromycin-13C,d3; (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-11-(((2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-2-ethyl-3,4,10-trihydroxy-13-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-3,5,8,10,12,14-hexamethyl-6-(methyl-13C-d3)-1-oxa-6-azacyclopentadecan-15-one; CP-62993-13C,d3; XZ-450-13C,d3; Azitrocin-13C,d3; Ribotrex-13C,d3; Sumamed-13C,d3; Trozocina-13C,d3; Zithromaz-13C,d3; Zitromax-13C,d3. Grade: 95% by HPLC; 98% atom D/13C. CAS No. 2983160-40-1. Molecular formula: C37[13C]H69D3N2O12. Mole weight: 753.01.
Azithromycin-[d3]
One of the isotopic labelled form of Azithromycin, which is an azalide macrolide antibiotic. Synonyms: Azithromycin-d3. Grade: 98% by HPLC; 98% atom D. CAS No. 163921-65-1. Molecular formula: C38H69D3N2O12. Mole weight: 752.0.
Azoxystrobin-[d4]
Azoxystrobin-[d4] is the labelled analogue of Azoxystrobin. Azoxystrobin is a systemic fungicide commonly used in agriculture. It is used as an active agent protecting plants and fruit/vegetables from fungal diseases. It inhibits mitochondrial respiration by blocking electron transfer between cytochromes b and c1. Synonyms: Azoxystrobin D4; (αE)-2-[[6-(2-Cyanophenoxy-d4)-4-pyrimidinyl]oxy]-α-(methoxymethylene)benzeneacetic Acid Methyl Ester; Methyl (E)-2-[2-[6-(2-Cyanophenoxy-d4)pyrimidin-4-yloxy]phenyl]-3-methoxypropenoate; Abound-d4; Amistar-d4; Bankit-d4; Cruiser Extreme-d4; Dynasty-d4; Heritage-d4; Ortiva-d4; Priori-d4; Protege-d4; Quadris-d4. Grade: ≥99% by HPLC; ≥98% atom D. CAS No. 1346606-39-0. Molecular formula: C22H13D4N3O5. Mole weight: 407.42.
Aztreonam-[d6]
Aztreonam-[d6] is the labelled analogue of Aztreonam, which is the first totally synthetic monocyclic β-lactam antibiotic used for the treatment of infections caused by gram-negative bacteria. Synonyms: Aztreonam D6; [2S-[2α,3β(Z)]]-2-[[(Z)-[1-(2-Amino-4-thiazolyl)-2-[[(2S,3S)-2-methyl-4-oxo-1-sulfo-3-azetidinyl]amino]-2-oxoethylidene]amino]oxy]-2-methylpropanoic-d6 Acid; Azthreonam-d6; Aztreon-d6; Monobactam-d6; Nebactam-d6; SQ 26776-d6; Squibb 26776-d6. Grade: ≥95%; ≥98% atom D. CAS No. 1127452-94-1. Molecular formula: C13H11D6N5O8S2. Mole weight: 441.47.
Azumolene-[13C3] Sodium Salt
Azumolene-[13C3] Sodium Salt is the labelled analogue of Azumolene. Azumolene is an experimental drug which is a derivative of dantrolene. Synonyms: Azumolene-13C3 Sodium Salt. CAS No. 1391062-50-2. Molecular formula: C10[13C3]H8BrN4NaO3. Mole weight: 374.10.
Bambuterol-[d9] hydrochloride
Bambuterol-[d9] hydrochloride is the labelled salt of Bambuterol, which is a long-acting beta-adrenergic receptor agonist (LABA) used in the treatment of asthma. Synonyms: Bambuterol-D9 hydrochloride; Dimethyl-carbamic acid 3-(2-tert-butylamino-D9-1-hydroxyethyl)-5-dimethylcarbamoyloxy-phenyl ester hydrochloride; N,N-Dimethylcarbamic Acid 3-[[(Dimethylamino)carbonyl]oxy]-5-[2-[(1,1-dimethylethyl-d9)amino]-1-hydroxyethyl]phenyl Ester Hydrochloride; Bambec-d9; KWD 2183-d9. Grade: 95% by HPLC; 98% atom D. CAS No. 1794810-59-5. Molecular formula: C18H21D9ClN3O5. Mole weight: 412.96.
Banoxantrone-[d12]
Banoxantrone-[d12] is the labelled analogue of Banoxantrone, which is a potent topoisomerase II inhibitor. Synonyms: Banoxantrone-D12; 1,4-Bis[[2-(dimethyloxidoamino)ethyl]amino]-5,8-dihydroxy-9,10-anthracenedione-d12; AQ4N-d12. Grade: ≥97%. CAS No. 1562067-05-3. Molecular formula: C22H16D12N4O6. Mole weight: 456.55.
Banoxantrone-[d12] dihydrochloride
Banoxantrone-[d12] dihydrochloride is the labelled salt of Banoxantrone, which is a potent topoisomerase II inhibitor. Synonyms: Banoxantrone D12 dihydrochloride; 1,4-Bis[[2-(dimethyloxidoamino)ethyl]amino]-5,8-dihydroxy-9,10-anthracenedione-d12 dihydrochloride; AQ4N-d12 dihydrochloride. Grade: ≥98%. CAS No. 1562066-98-1. Molecular formula: C22H18D12Cl2N4O6. Mole weight: 529.48.
Baquiloprim-[d6]
Baquiloprim-[d6] is the labelled analogue of Baquiloprim. Baquiloprim is an antifolate that can be used as an antibacterial. Synonyms: Baquiloprim-D6; 5-(8-Dimethylamino-D6-7-methylquinolin-5-ylmethyl)-pyrimidine-2,4-diamine. Grade: 95% by HPLC; 98% atom D. CAS No. 1228182-50-0. Molecular formula: C17H14D6N6. Mole weight: 314.42.
Barium carbonate-[13C]
Barium carbonate-[13C]. Synonyms: Barium carbonate-13C. Grade: 98% atom 13C. CAS No. 51956-33-3. Molecular formula: [13C]BaO3. Mole weight: 198.33.
(±)-Bay K 8644
(±)-Bay K 8644 is a L-type Ca2+ channel activator. It exhibits positive inotropic, vasoconstrictive and behavioral effects in vivo. Uses: Reprogramming. Synonyms: Bay K 8644; (+/-)-BAY K 8644; BAY-K-8644; methyl 2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-1,4-dihydropyridine-3-carboxylate. Grade: 98%. CAS No. 71145-03-4. Molecular formula: C16H15F3N2O4. Mole weight: 356.3.
Bazedoxifene-[d4] Acetate
Bazedoxifene-[d4] Acetate is an isotope labelled Bazedoxifene Acetate, which is a nonsteroidal selective estrogen receptor modulator for the treatment of osteoporosis in postmenopausal women. Synonyms: Bazedoxifene-d4 Acetate; TSE 424-d4; Viviant-d4; WAY-TES 424-d4. Grade: >95%; 98% atom D. CAS No. 1133695-49-4. Molecular formula: C32H38N2O5. Mole weight: 534.7.