BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Boc-(±)-trans-4-(2-naphthyl)pyrrolidine-3-carboxylic acid | Synonyms: Boc-(±)-trans-4-(2-naphthyl)-pyrrolidine-3-carboxylic acid. Grades: ≥ 98% by HPLC. CAS No. 959583-04-1. Molecular formula: C20H23NO4. Mole weight: 341.4. |  |
| Boc-(±)-trans-4-(2-thienyl)-pyrrolidine-3-carboxylic acid | Cas No. 959581-75-0. Molecular formula: C14H19NO4S. Mole weight: 297.37. | |
| Boc-(±)-trans-4-(2-trifluoromethylphenyl)pyrrolidine-3-carboxylic acid | Synonyms: (±)-trans-1-(t-Butoxycarbonyl)-4-(2-trifluoromethylphenyl)pyrrolidine-3-carboxylic acid; (3S,4R)-1-[(2-methylpropan-2-yl)oxycarbonyl]-4-[2-(trifluoromethyl)phenyl]pyrrolidine-3-carboxylic acid. Grades: ≥ 95%. CAS No. 1381947-36-9. Molecular formula: C17H20F3NO4. Mole weight: 359.34. | |
| Boc-(±)-trans-4-(3,4-dimethoxyphenyl)pyrrolidine-3-carboxylic acid | Synonyms: Boc-(±)-trans-4-(3,4-dimethoxy-phenyl)-pyrrolidine-3-carboxylic acid. Grades: ≥ 98% by HPLC. CAS No. 959580-91-7. Molecular formula: C18H25NO6. Mole weight: 351.39. | |
| Boc-(±)-trans-4-(3,5-dimethoxyphenyl)pyrrolidine-3-carboxylic acid | Synonyms: Boc-(±)-trans-4-(3,5-dimethoxy-phenyl)-pyrrolidine-3-carboxylic acid. CAS No. 1392210-31-9. Molecular formula: C18H25NO6. Mole weight: 351.39. | |
| Boc-(±)-trans-4-(3-hydroxyphenyl)pyrrolidine-3-carboxylic acid | Synonyms: (±)-trans-1-(t-Butoxycarbonyl)-4-(3-hydroxyphenyl)pyrrolidine-3-carboxylic acid; (3S,4R)-4-(3-hydroxyphenyl)-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-3-carboxylic acid. CAS No. 959575-09-8. Molecular formula: C16H21NO5. Mole weight: 307.34. | |
| Boc-(±)-trans-4-(3-thienyl)-pyrrolidine-3-carboxylic acid | Cas No. 959579-56-7. Molecular formula: C14H19NO4S. Mole weight: 297.37. | |
| Boc-(±)-trans-4-(4-hydroxyphenyl)pyrrolidine-3-carboxylic acid | Synonyms: (±)-trans-1-(t-Butoxycarbonyl)-4-(4-hydroxyphenyl)pyrrolidine-3-carboxylic acid; (3S,4R)-4-(4-hydroxyphenyl)-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-3-carboxylic acid. CAS No. 959574-90-4. Molecular formula: C16H21NO5. Mole weight: 307.34. | |
| Boc-(±)-trans-4-(4-methylphenyl)pyrrolidine-3-carboxylic acid | Synonyms: (±)-trans-1-(t-Butoxycarbonyl)-4-(4-methylphenyl)pyrrolidine-3-carboxylic acid; (3R,4S)-4-(4-methylphenyl)-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-3-carboxylic acid. Grades: ≥ 98% by HPLC. CAS No. 1360437-60-0. Molecular formula: C17H23NO4. Mole weight: 305.37. | |
| Boc-(±)-trans-4-(6-methoxy-3-pyridinyl)pyrrolidine-3-carboxylic acid | Synonyms: (±)-trans-1-(t-Butoxycarbonyl)-4-(6-methoxy-3-pyridinyl)pyrrolidine-3-carboxylic acid; (3S,4R)-4-(6-Methoxypyridin-3-yl)-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-3-carboxylic acid. Grades: ≥ 99% (HPLC). CAS No. 1392213-90-9. Molecular formula: C16H22N2O5. Mole weight: 322.36. | |
| Boc-trans-4-aminocyclohexane carboxylic acid | Boc-trans-4-aminocyclohexane carboxylic acid (CAS# 53292-89-0) is a reagent to synthesize N-myristoyltransferase and CD38 inhibitors. Synonyms: Boc-1,4-trans-Achc-OH; Boc-trans-4-aminocyclohexane-1-carboxylic acid. Grades: ≥ 99 % (GC). CAS No. 53292-89-0. Molecular formula: C12H21NO4. Mole weight: 243.27. | |
| Boc-Trp(1-Me)-OH | Synonyms: (S)-2-((tert-Butoxycarbonyl)amino)-3-(1-methyl-1H-indol-3-yl)propanoic acid; N-Boc-1-methyl-L-tryptophan; N-(tert-butoxycarbonyl)-1-methyltryptophan. CAS No. 109927-44-8. Molecular formula: C17H22N2O4. Mole weight: 318.37. | |
| Boc-Trp(F)-ONp | Molecular formula: C23H23N3O7. Mole weight: 453.4. | |
| Boc-Trp(Mts)-aldehyde | Synonyms: tert-butyl [(2S)-1-oxo-3-{1-[(2,4,6-trimethylphenyl)sulfonyl]-1H-indol-3-yl}propan-2-yl]carbamate; N-Boc-2(S)-2-amino-3-{1-[(2,4,6-trimethylphenyl)sulfonyl]-1H-indol-3-yl}propanal. CAS No. 1026493-36-6. Molecular formula: C25H30N2O5S. Mole weight: 470.58. | |
| Boc-Try(3-cl)-OH DCHA | Synonyms: Boc-D-3-chlorotyrosine dicyclohexylamine salt; Dicyclohexylamine (S)-2-(tert-butoxycarbonylamino)-3-(3-chloro-4-hydroxyphenyl)propanoic acid. Molecular formula: C14H18NO5Cl·C12H23N. Mole weight: 497.1. | |
| Boc-Tyr(CF3)-OH | Synonyms: Boc-Phe(4-OCF3)-OH; N-α-(t-Butoxycarbonyl)-O-trifluoromethyl-L-tyrosine; N-α-(t-Butoxycarbonyl)-4-trifluoromethoxy-L-phenylalanine; (2S)-2-[(Tert-butoxy)carbonylamino]-3-[4-(trifluoromethoxy)phenyl]propanoic acid. CAS No. 1041011-20-4. Molecular formula: C15H18F3NO5. Mole weight: 349.31. | |
| Boc-Tyr(Me)-OMe | Synonyms: Boc-O-methyl-L-tyrosine methyl ester; (S)-methyl 2-((tert-butoxycarbonyl)amino)-3-(4-methoxyphenyl)propanoate. Grades: ≥ 95%. CAS No. 91790-24-6. Molecular formula: C16H23NO5. Mole weight: 309.3. | |
| Boc-Tyr-OtBu | Synonyms: Boc-L-Tyr-OtBu; Tert-butyl (2S)-3-(4-hydroxyphenyl)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoate. CAS No. 18938-60-8. Molecular formula: C18H27NO5. Mole weight: 337.4. | |
| Boc-Val-Cit-OH | Boc-Val-Cit-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Synonyms: (2S) -5- (carbamoylamino) -2- [ [ (2S) -3-methyl-2- [ (2-methylpropan-2-yl) oxycarbonylamino] butanoyl] amino] pentanoic acid. Grades: ≥95.0%. CAS No. 870487-08-4. Molecular formula: C16H30N4O6. Mole weight: 374.43. | |
| Bombin H7 | Bombin H7 was found in Bombina orientalis. It has antibacterial activity against Bacillus megaterium BmII (MIC=3.3 microM), and Escherichia coli D22 (MIC=3.7 microM). | |
| Bombinin H1 | Bombinin H1 was found in Bombina variegata. It has antimicrobial and hemolytic activities. | |
| Bombinin H4 | Bombinin H4 was found in Bombina variegata. It has antimicrobial and hemolytic activities. | |
| Bombinin-H5 | Bombinin H5 was found in Bombina variegata. It has antimicrobial and hemolytic activities. | |
| Bombinin H-like peptide 1 | Bombinin H-like peptide 1 was found in Bombina orientalis. It has antimicrobial activity. | |
| Bombinin-like peptide 3 | Bombinin-like peptide 3 was found in Bombina orientalis. It has antimicrobial activity, but no hemolytic activity. Preference on killing Gram-negative non-enteric bacteria. Synonyms: BLP-3. CAS No. 138220-02-7. Molecular formula: C108H183N31O29. Mole weight: 2379.79. | |
| Bombinin-like peptide 4 | Bombinin-like peptide 4 was found in Bombina orientalis. It has antimicrobial activity, but no hemolytic activity. Preference on killing Gram-negative non-enteric bacteria. Synonyms: BLP-4. | |
| Bombinin-like peptide 7 | Bombinin-like peptide 7 was found in Bombina orientalis. Bombinin-like peptide 7 is an antimicrobial peptide with activity against Gram-positive and -negative bacteria and fungi. It shows activity against P.acnes (MIC=5 μM), E.coli (MIC=5-6.3 μM), S.aureus (MIC=5-6.3 μM), M.luteus, S.cerevisiae and C.albicans (MIC=10-12.5 μM). Bombinin-like peptide 7 also shows anticancer activity against three human hepatoma cell lines and weak hemolytic activity against human erythrocytes. Synonyms: BLP-7. | |
| Bombolitin V | Bombolitin V is a mast cell degranulating peptide from the venom of the bumblebee Megabombus pennsylvanicus. Synonyms: Bombolitin-5. Grades: >96% by HPLC. CAS No. 95648-98-9. Molecular formula: C81H144N22O19. Mole weight: 1730.14. | |
| Bovine Beta-defensin 10 | Bovine Beta-defensin 10 is an antibacterial peptide isolated from Bos taurus. It has activity against gram-positive bacteria and gram-negative bacteria. Synonyms: Gln-Gly-Val-Arg-Ser-Tyr-Leu-Ser-Cys-Trp-Gly-Asn-Arg-Gly-Ile-Cys-Leu-Leu-Asn-Arg-Cys-Pro-Gly-Arg-Met-Arg-Gln-Ile-Gly-Thr-Cys-Leu-Ala-Pro-Arg-Val-Lys-Cys-Cys-Arg. | |
| Bovine Beta-defensin 3 | Bovine Beta-defensin 3 is an antibacterial peptide isolated from Bos taurus. It has activity against gram-positive bacteria and gram-negative bacteria. Synonyms: Gln-Gly-Val-Arg-Asn-His-Val-Thr-Cys-Arg-Ile-Asn-Arg-Gly-Phe-Cys-Val-Pro-Ile-Arg-Cys-Pro-Gly-Arg-Thr-Arg-Gln-Ile-Gly-Thr-Cys-Phe-Gly-Pro-Arg-Ile-Lys-Cys-Cys-Arg-Ser-Trp. | |
| Bovine Beta-defensin 5 | Bovine Beta-defensin 5 is an antibacterial peptide isolated from Bos taurus. It has activity against gram-positive bacteria and gram-negative bacteria. Synonyms: Gln-Val-Val-Arg-Asn-Pro-Gln-Ser-Cys-Arg-Trp-Asn-Met-Gly-Val-Cys-Ile-Pro-Ile-Ser-Cys-Pro-Gly-Asn-Met-Arg-Gln-Ile-Gly-Thr-Cys-Phe-Gly-Pro-Arg-Val-Pro-Cys-Cys-Arg-Arg-Trp. | |
| Bovine Neutrophil beta-defensin 5 | Neutrophil beta-defensin 5 is an antimicrobial peptide found in Bos taurus (Bovine), and has antibacterial activity. Synonyms: BNBD 5; Neutrophil beta-defensin 5. Grades: >98%. | |
| BQ-3020 | BQ-3020 is a potent and selective ETB endothelin receptor agonist (Ki = 0.18 and 970 nM at human ETB and ETA receptors, respectively). Synonyms: endothelin receptor antagonist; Acetyl-(Ala11·15)-Endothelin-1 (6-21). CAS No. 143113-45-5. Molecular formula: C96H140N20O25S. Mole weight: 2006.3. | |
| Bradykinin | Bradykinin is a nonapeptide messenger produced from kallidin in the blood. Bradykinin has the selectivity for B2 over B1 receptors. It exhibits hypotensive and anti-inflammatory properties. Uses: Hypotensive agent. Synonyms: H-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-OH; L-arginyl-L-prolyl-L-prolyl-glycyl-L-phenylalanyl-L-seryl-L-prolyl-L-phenylalanyl-L-arginine; L-Bradykinin; Kallidin I; Callidin I; Kallidin 9. Grades: ≥95%. CAS No. 58-82-2. Molecular formula: C50H73N15O11. Mole weight: 1060.21. | |
| Bradykinin 1-3 | Bradykinin 1-3, a 3-amino acid residue peptide fragment of Bradykinin, is an amino-truncated Bradykinin cleaved by Prolyl endopeptidase. Synonyms: Bradykinin (1-3); Arginyl-prolyl-proline; arginylprolylproline; L-Arginyl-L-prolyl-L-proline; H-RPP-OH. Grades: 95%. CAS No. 23815-91-0. Molecular formula: C16H28N6O4. Mole weight: 368.43. | |
| Bradykinin 1-5 | Bradykinin 1-5 is the main stable metabolite of Bradykinin and is formed by proteolysis of angiotensin-converting enzyme (ACE). Synonyms: H-RPPGF-OH; L-arginyl-L-prolyl-L-prolyl-glycyl-L-phenylalanine; Bradykinin (1-5); Bradykinin Fragment 1-5; 1-5-Bradykinin (9Cl); N-[2-({[1-(Arginylprolyl)pyrrolidin-2-yl](hydroxy)methylidene}amino)-1-hydroxyethylidene]phenylalanine. Grades: ≥95%. CAS No. 23815-89-6. Molecular formula: C27H40N8O6. Mole weight: 572.66. | |
| Bradykinin 1-6 | Bradykinin 1-6, a stable metabolite of Bradykinin, is an amino-truncated Bradykinin peptide cleaved by carboxypeptidase Y (CPY). Synonyms: H-Arg-Pro-Pro-Gly-Phe-Ser-OH; L-arginyl-L-prolyl-L-prolyl-glycyl-L-phenylalanyl-L-serine; (S)-2-((S)-2-(2-((S)-1-((S)-1-((S)-2-amino-5-guanidinopentanoyl)pyrrolidine-2-carbonyl)pyrrolidine-2-carboxamido)acetamido)-3-phenylpropanamido)-3-hydroxypropanoic acid; Bradykinin (1-6). Grades: 95%. CAS No. 23815-88-5. Molecular formula: C30H45N9O8. Mole weight: 659.73. | |
| Bradykinin 2-9 | Bradykinin 2-9, a metabolite of Bradykinin, is an amino-truncated Bradykinin peptide cleaved by Aminopeptidase P. Synonyms: Des-Arg1-bradykinin; H-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-OH; L-prolyl-L-prolyl-glycyl-L-phenylalanyl-L-seryl-L-prolyl-L-phenylalanyl-L-arginine; Bradykinin fragment 2-9; 2-9-Bradykinin. Grades: ≥95%. CAS No. 16875-11-9. Molecular formula: C44H61N11O10. Mole weight: 904.02. | |
| Bradykinin-GN_4 antimicrobial peptide precursor | Bradykinin-GN_4 antimicrobial peptide precursor is originally from Amolops granulosus. | |
| Bradykinin-TR1 bradykinin-related peptide precursor | Bradykinin-TR1 bradykinin-related peptide precursor is originally from Amolops granulosus. | |
| Br-AFP1 | Br-AFP1 is originally from Brassica rapa subsp. chinensis. | |
| Brain natriuretic peptide (1-32) (human) | An agonist at atrial natriuretic peptide (ANP) receptor A (NRP1) which is secreted from cardiac ventricles in response to volume increase and pressure overload. It exhibits natriuretic, vasodilatory and lusitropic activity and suppresses sympathetic and renin-angiotensin-aldosterone systems in vivo, and decreases de novo collagen synthesis as well as increases MMP gene expression in vitro. Synonyms: Brain Natriuretic Peptide-32 human; BNP-32 (human); Nesiritide; H-Ser-Pro-Lys-Met-Val-Gln-Gly-Ser-Gly-Cys(1)-Phe-Gly-Arg-Lys-Met-Asp-Arg-Ile-Ser-Ser-Ser-Ser-Gly-Leu-Gly-Cys(1)-Lys-Val-Leu-Arg-Arg-His-OH; L-seryl-L-prolyl-L-lysyl-L-methionyl-L-valyl-L-glutaminyl-glycyl-L-seryl-glycyl-L-cysteinyl-L-phenylalanyl-glycyl-L-arginyl-L-lysyl-L-methionyl-L-alpha-aspartyl-L-arginyl-L-isoleucyl-L-seryl-L-seryl-L-seryl-L-seryl-glycyl-L-leucyl-glycyl-L-cysteinyl-L-lysyl-L-valyl-L-leucyl-L-arginyl-L-arginyl-L-histidine (10->26)-disulfide. Grades: ≥99% by HPLC. CAS No. 124584-08-3. Molecular formula: C143H244N50O42S4. Mole weight: 3464.04. | |
| Brain Natriuretic Peptide (BNP) (1-32), rat | Brain Natriuretic Peptide (BNP) (1-32), rat is a 32-amino acid polypeptide secreted by the ventricle in response to overstretching of cardiomyocytes. Synonyms: Brain Natriuretic Peptide-32 (rat); BNP (1-32), rat; H-Asn-Ser-Lys-Met-Ala-His-Ser-Ser-Ser-Cys(1)-Phe-Gly-Gln-Lys-Ile-Asp-Arg-Ile-Gly-Ala-Val-Ser-Arg-Leu-Gly-Cys(1)-Asp-Gly-Leu-Arg-Leu-Phe-OH; L-asparagyl-L-seryl-L-lysyl-L-methionyl-L-alanyl-L-histidyl-L-seryl-L-seryl-L-seryl-L-cysteinyl-L-phenylalanyl-glycyl-L-glutaminyl-L-lysyl-L-isoleucyl-L-alpha-aspartyl-L-arginyl-L-isoleucyl-glycyl-L-alanyl-L-valyl-L-seryl-L-arginyl-L-leucyl-glycyl-L-cysteinyl-L-alpha-aspartyl-glycyl-L-leucyl-L-arginyl-L-leucyl-L-phenylalanine (10->26)-disulfide. Grades: 95%. CAS No. 133448-20-1. Molecular formula: C146H239N47O44S3. Mole weight: 3452.94. | |
| Bremelanotide Acetate | Bremelanotide Acetate is a heptapeptide melanocortin agonist. Bremelanotide, formerly known as PT-141, employed in clinical trials for sexual dysfunction including both male erectile dysfunction (ED) and female sexual dysfunction or disorder (FSD), is a f. Synonyms: PT141 acetate. CAS No. 1607799-13-2. Molecular formula: C52H72N14O12. Mole weight: 1085.22. | |
| Brevinin-1 | The unique antimicrobial peptide named brevinin-1 was isolated from the skin of the frog, Rana brevipoda porsa. The minimum inhibitory concentration of brevinin-1 against the growth of St. aureus and E. coli was determined to be 8 micrograms/ml and 34 micrograms/ml. Synonyms: Brevinin-1; 145963-49-1; brevinin-1 protein, Rana; Brevinin 1; AMGDYQVEJJSZSQ-IMDMOUBVSA-N; Brevinin-1 (KFHEKHHSHRGY-acid); C121H202N28O26S2; RS-2012; C121-H202-N28-O26-S2. CAS No. 145963-49-1. Molecular formula: C121H202N28O26S2. Mole weight: 2529.2. | |
| Brevinin-1-01 | Brevinin-1-01 was found in Amolops sp. jingdongensis. It has antimicrobial activity. | |
| Brivudine 5'-Diphosphate Tristriethyl Ammonium Salt | Brivudine 5'-Diphosphate Tristriethyl Ammonium Salt is derived from Brivudine, which is a nucleoside analog which causes induction of neuronal differentiation in human reporter cell lines and adult stem cells. Anti-Herpes medication. Molecular formula: C11H15BrN2O11P2 C6H15N. Mole weight: 493.10. | |
| Brivudine 5'-Monophosphate | Brivudine 5'-Monophosphate is a hetero-dinucleotide that acts as an anti-tumor agent against AH13 rat sarcoma cells. A nucleotide derivative which is an active species of the novel anticancer drug, NB 1011. Anti-viral. Synonyms: BVDU 5'-Monophosphate; (E)-5-(2-Bromovinyl)-2'-deoxyuridine 5'-Monophosphate; 5-[(1E)-2-Bromoethenyl]-2'-deoxy-5'-uridylic Acid; (E)-5-(2-bromoethenyl)-2'-deoxy-5'-uridylic Acid. CAS No. 80860-82-8. Molecular formula: C11H14BrN2O8P. Mole weight: 413.12. | |
| Brivudine 5'-Triphosphate Ammonium | Brivudine 5'-Triphosphate Ammonium Salt is derived from Brivudine, which is a nucleoside analog which causes induction of neuronal differentiation in human reporter cell lines and adult stem cells. Anti-herpes medication. Synonyms: 5-(2-Bromovinyl)-2'-deoxyuridine-5'-triphosphate; [[(2R,3S,5R)-5-[5-[(E)-2-bromoethenyl]-2,4-dioxopyrimidin-1-yl]-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate; Uridine 5'-(tetrahydrogen triphosphate), 5-(2-bromoethenyl)-2'-deoxy-, (E)-; BVdUTP; BV(5)Dutp; Bvdu-tp; SCHEMBL442341; SCHEMBL442343; CHEMBL4594370; (E)-5-(2-Bromovinyl)-dUTP; Brivudine 5'-Triphosphate Ammonium; E-5-Bromovinyl-2'-deoxyuridine triphosphate; (E)-5-(2-Bromovinyl)-2'-deoxyuridine triphosphate; (e)-5-(2-bromovinyl)-2'-deoxyuridine 5'-triphosphate; Uridine 5'-(tetrahydrogen triphosphate), 5-[(1E)-2-bromoethenyl]-2'-deoxy-; ((2R,3S,5R)-5-(5-((E)-2-Bromovinyl)-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxytetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate; [[(2R,3S,5R)-5-[5-[(E)-2-bromovinyl]-2,4-dioxo-pyrimidin-1-yl]-3-hydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl] phosphono hydrogen phosphate. Molecular formula: C11H16BrN2O14P3. Mole weight: 573.08. | |
| Brochocin C | Brochocin C, produced by Brochothrix campestris, is active against many strains of the closely related meat spoilage organism Brochothrix thermosphacta and a wide range of other gram-positive bacteria, including spores of Clostridium botulinum. | |
| BTD-1 | BTD-1 is produced by Papio anubis. BTD-1 has antimicrobial activity against the Gram-negative bacterium E.coli ML35, the Gram-positive bacterium S.aureus 502a, and the fungus C.albicans 16820. BTD-2 is more effective against E.coli than BTD-1. | |
| BTD-2 | BTD-2 is produced by Papio anubis. BTD-2 has antimicrobial activity against the Gram-negative bacterium E.coli ML35, the Gram-positive bacterium S.aureus 502a, and the fungus C.albicans 16820. BTD-2 is more effective against E.coli than BTD-1. | |
| BTD-4 | BTD-4 is produced by Papio anubis. It has antibacterial and antifungal activity. | |
| BTD-7 | BTD-7 is produced by Papio anubis. BTD-7 has antimicrobial activity against the Gram-negative bacterium E.coli ML35, the Gram-positive bacterium S.aureus 502a, and the fungus C.albicans 16820. | |
| BTL | BTL was isolated from Bacillus subtilis B-TL2. BTL shows relatively low identity to other antimicrobial peptides from bacteria. The peptide exhibited strong inhibitory activity against mycelial growth of Bipolaris maydis, Alternaria brassicae, Aspergillus niger, Cercospora personata. | |
| Bucladesine Impurity 2 | 6-MB-cAMP is a selective stimulator of protein kinase A (cAMP agonist), which is commonly used as an Epac-negative control. Synonyms: N6- Monobutyryladenosine- 3', 5'- cyclic monophosphate, sodium salt. Grades: ≥ 97% by HPLC. CAS No. 70253-67-7. Molecular formula: C14H17N5O7P · Na. Mole weight: 421.3. | |
| Buforin-1 | The source of Buforin-1 is Bufo gargarizans. Buforin I is generated from histone H2A by pepsin-directed proteolysis in the cytoplasm of gastric gland cells. After secretion into the gastric lumen, buforin I remains adhered to the mucous biofilm that lines the stomach, thus providing a protective antimicrobial coat. Buforins also are known to possess anti-endotoxin and anticancer activities, thus making these peptides attractive reagents for pharmaceutical applications. | |
| Buforin-2 | Buforin II is a highly potent antimicrobial peptide which was derived from buforin I, a peptide isolated from the stomach of the Bufo gargarizans. Buforin II is an α-helical antimicrobial peptide, however it has far stronger antimicrobial activity against a broad spectrum of microorganisms compared with other α-helical antimicrobial peptides. Grades: >95% by HPLC. Mole weight: 2434.85. | |
| Buforin-EC | Buforin-EC was found in Euphlyctis cyanophlyctis. It has antibacterial activity against E.coli HP101BA (MIC=9.6 μM), K.pneumoniae PTCC1388 (MIC=10.6 μM), M.luteus PTCC1625 (MIC=6.0 μM) and S.aureus PTCC1431 (MIC=8.1 μM). Buforin-EC has no or very limited (<3%) hemolytic activity at concentrations of 15 μg/ml and 60 μg/ml, respectively. | |
| Buforin I | Buforin I is a 39-amino acid AMP that was first isolated from the stomach tissue of the Asian toad Bufo gargarizans. Compared with other amphibian AMPs, such as magainin 2, buforin I shows much stronger antimicrobial activities in vitro against a broad spectrum of microorganisms. Buforins have anti-endotoxin and anticancer activities. Synonyms: H-Ala-Gly-Arg-Gly-Lys-Gln-Gly-Gly-Lys-Val-Arg-Ala-Lys-Ala-Lys-Thr-Arg-Ser-Ser-Arg-Ala-Gly-Leu-Gln-Phe-Pro-Val-Gly-Arg-Val-His-Arg-Leu-Leu-Arg-Lys-Gly-Asn-Tyr-OH; L-alanyl-glycyl-L-arginyl-glycyl-L-lysyl-L-glutaminyl-glycyl-glycyl-L-lysyl-L-valyl-L-arginyl-L-alanyl-L-lysyl-L-alanyl-L-lysyl-L-threonyl-L-arginyl-L-seryl-L-seryl-L-arginyl-L-alanyl-glycyl-L-leucyl-L-glutaminyl-L-phenylalanyl-L-prolyl-L-valyl-glycyl-L-arginyl-L-valyl-L-histidyl-L-arginyl-L-leucyl-L-leucyl-L-arginyl-L-lysyl-glycyl-L-asparagyl-L-tyrosine. Grades: ≥90% by HPLC. CAS No. 173010-28-1. Molecular formula: C184H318N70O47. Mole weight: 4262.93. | |
| Buforin II | It is a 21 amino acid peptide derived from Buforin I peptide that is isolated from the Asian toad Bufo gargarizans. It has anti-microbial activity by penetrating bacteria and inhibiting cellular functions. Compared with magainin 2, It binds DNA and RNA from E.coli with a much greater affinity. It is also considered to be a cell-delivery peptide and has been shown to deliver SiRNAs into cells followed by effective mRNA degradation. Synonyms: H-Thr-Arg-Ser-Ser-Arg-Ala-Gly-Leu-Gln-Phe-Pro-Val-Gly-Arg-Val-His-Arg-Leu-Leu-Arg-Lys-OH; Buforin; L-Threonyl-L-arginyl-L-seryl-L-seryl-L-arginyl-L-alanylglycyl-L-leucyl-L-glutaminyl-L-phenylalanyl-L-prolyl-L-valylglycyl-L-arginyl-L-valyl-L-histidyl-L-arginyl-L-leucyl-L-leucyl-L-arginyl-L-lysine; Buforin 2. Grades: ≥95%. CAS No. 172998-24-2. Molecular formula: C106H184N40O26. Mole weight: 2434.88. | |
| Buthinin | Buthinin was found in Androctonus australis. It is active against both Gram-positive and Gram-negative bacteria. | |
| Butyrivibriocin AR10 | Butyrivibriocin AR10 is a new cyclic bacteriocin produced by the ruminal anaerobe Butyrivibrio fibrisolvens AR10. | |
| Butyrolacton-BCP-COOH | Synonyms: 3-(5-oxotetrahydrofuran-2-yl)bicyclo[1.1.1]pentane-1-carboxylic acid; 3-Butyrolacton-BCP-1-carboxylic acid. Molecular formula: C10H12O4. Mole weight: 196.20. | |
| BV6 | BV-6 is a selective inhibitor of apoptosis (IAP) family with IC50 value of 7.2 μM when tested with H460 cells. It acts by promoting glioblastoma cancer stem-like cell differentiation by activating NF-κB. BV-6 induces autoubiquitination and proteasomal degradation of IAP1 and XIAP in MDA-MB-231 cells at 5 μM. In BALB/c mice model with transplanted abdominal cavities from donor mouse uterine tissue, intraperitoneally with BV-6 repressed the advancement of endometriosis, cell proliferative activity via inhibiting the expression of IAPs. In hematological THP-1 cells, pre-treatment with BV-6 increased the CIK cells killing ability and the same results were achieved in solid malignancy RH30 cells. Grades: ≥98%. CAS No. 1001600-56-1. Molecular formula: C70H96N10O8. Mole weight: 1205.57. | |
| BVD 10 | BVD 10 is a selective NPY Y1 receptor antagonist (Ki = 25.7, 1420, 2403 and 7100 nM at Y1, Y2, Y4 and Y5 receptors, respectively) with no activity at Y4 receptors. Synonyms: BVD 10; BVD10; BVD-10. Grades: >98%. CAS No. 262418-00-8. Molecular formula: C58H92N16O13. Mole weight: 1221.46. | |
| Bz-Arg-4-Abz-OH HCl | Synonyms: Nα-Benzoyl-L-arginine 4-carboxyanilide hydrochloride; Bz-Arg-4-Abz-OH Hydrochloride. Grades: ≥ 98% by TLC. Molecular formula: C20H23N5O4.HCl. Mole weight: 433.89. | |
| BzO-BCP-NH-Boc | Synonyms: 3-(t-butoxycarbonylamino)bicyclo[1. 1. 1]pentan-1-yl benzoate. Molecular formula: C17H21NO4. Mole weight: 303.36. | |
| C 21 | C 21 is a selective protein arginine methyltransferase 1 (PRMT1) inhibitor (IC50 = 1.8 μM) with 5-fold selectivity for PRMT1 over PRMT6 and >250-fold selectivity over PRMT3 and CARM1. Synonyms: C21; C-21; N-Acetyl-L-serylglycyl-N5-(2-chloroethanimidoyl)-L-ornithylglycyl-L-lysylglycylglycyl-L-lysylglycyl-L-leucylglycyl-L-lysylglycylglycyl-L-alanyl-L-lysyl-L-arginyl-L-histidyl-L-arginyl-L-lysyl-L-valine. Grades: >98%. CAS No. 1229236-78-5. Molecular formula: C90H161ClN36O24. Mole weight: 2166.92. | |
| C2,C8-Dimethyladenosine | C2,C8-Dimethyladenosine, a nucleoside derivative prevalently employed in the biomedical sector, assumes a critical function in the amalgamation of innovative pharmaceuticals for the purpose of combating diverse ailments. Its profound attributes render it a coveted asset for both researchers and pharmaceutical firms engaged in the exploration and advancement of medicinal remedies. Molecular formula: C12H17N5O4. Mole weight: 295.30. | |
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