BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Cladribine 5'-Monophosphate Ammonium Salt | Cladribine 5'-Monophosphate Ammonium Salt can be used as an antiviral, antibacterial and antileukemic agent. Grades: 97%. Molecular formula: C10H16ClN6O6P. Mole weight: 382.7. |  |
| Class II sec-dependent bacteriocin | Class II sec-dependent bacteriocin is from Enterococcus hirae. It has antimicrobial activity. | |
| Clavanin-A | Clavanin A was found in invertebrate Styela clava. It has antibacterial and antifungal activity. Clavanin A was in vitro evaluated against Staphylococcus aureus and Escherichia coli as well as toward L929 mouse fibroblasts and skin primary cells (SPCs). Grades: >96% by HPLC. Molecular formula: C131H184N34O27. Mole weight: 2667.07. | |
| Clavanin-B | Clavanin B is an alpha-helical antimicrobial peptide isolated from Styela clava. Molecular formula: C131H184N36O27. Mole weight: 2695.08. | |
| Clavanin-C | Clavanin-C was found in Styela clava. It has antimicrobial activity against E.coli, L.monocytogenes and C.albicans. | |
| Clavanin-D | Clavanin-D was found in Styela clava. It has antimicrobial activity against E.coli, L.monocytogenes and C.albicans. Molecular formula: C131H191N35O26. Mole weight: 2672.13. | |
| Clavanin-E | Clavanin E has antimicrobial activity. The source of Clavanin E is invertebrate Styela clava. Grades: >97% by HPLC. Molecular formula: C130H193N35O25. Mole weight: 2646.14. | |
| Clavaspirin | Clavaspirin was found in Styela clava. It exhibits broad-spectrum antimicrobial activity against both Gram-positive and Gram-negative bacteria. Clavaspirin also has potent hemolytic activity. | |
| CleanCap Reagent AU | | |
| Clindamycin 2,4-Diphosphate | Clindamycin 2,4-Diphosphate (Clindamycin Phosphate EP Impurity I) is an impurity of Clindamycin which is a semi-synthetic antibiotic. Synonyms: Methyl 7-chloro-6,7,8-trideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio-L-threo-α-D-galacto-octopyranoside 2,4-bis(Dihydrogen Phosphate); Clindamycin Phosphate EP Impurity I. Grades: 93%. CAS No. 1309048-48-3. Molecular formula: C18H35ClN2O11P2S. Mole weight: 584.94. | |
| Clindamycin 2-Phosphate Sulfoxide(Mixture of Diastereomers) | Clindamycin 2-Phosphate Sulfoxide is a degradation product of Clindamycin phosphate after the stressing test. Clindamycin phosphate impurity. Synonyms: 7-Chloro-1,6,7,8-tetradeoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-(methylsulfinyl)-L-threo-α-D-galactooctopyranose 2-(Dihydrogen Phosphate). Grades: 95%. CAS No. 1228573-90-7. Molecular formula: C18H34ClN2O9PS. Mole weight: 520.96. | |
| Clindamycin Phosphate Sulfoxide Trans-N-oxide | Clindamycin Phosphate Sulfoxide Trans-N-oxide, a notable biomedical compound, unveils remarkable potential in combating diverse bacterial infections. Acquired from Clindamycin, this compound manifests intensified antibacterial efficacy against an array of pathogens, primarily Gram-positive bacteria. Remarkably, its mechanism of action involves impeding bacterial protein synthesis, effectively targeting ailments like skin and soft tissue infections, respiratory tract infections, and bone and joint infections. Molecular formula: C18H34ClN2O10PS. Mole weight: 536.96. | |
| Clindamycin Pyrophosphate Triethylamine Salt | Clindamycin Pyrophosphate is an impurity of Clindamycin, which is a semi-synthetic antibiotic prepared from Lincomycin. Grades: 96%. Molecular formula: C18H35ClN2O11P2S xC6H15N. Mole weight: 584.94. | |
| Cliotide T1 | Cliotide T1 was found in Clitoria ternatea. It is active against Gram-negative bacteria E.coli, K.pneumoniae and P.aeruginosa. Cliotide T1 also has hemolytic and cytotoxic activity. | |
| Cliotide T10 | Cliotide T10 was found in Clitoria ternatea. It probably participates in a plant defense mechanism. | |
| Cliotide T12 | Cliotide T12 was found in Clitoria ternatea. It probably participates in a plant defense mechanism. | |
| Cliotide T19 | Cliotide T19 was found in Clitoria ternatea. It is active against Gram-negative bacterium E.coli under low-salt conditions. It is not active against Gram-positive bacterium S.aureus up to a concentration of 100 μM under low-salt conditions. Cliotide T19 also exhibits immunomodulatory activity but no cytotoxicity in vitro. | |
| Cliotide T2 | Cliotide T2 was found in Clitoria ternatea. It is not active against Gram-negative bacteria E.coli, K.pneumoniae and P.aeruginosa at concentration up to 100 μM. Cliotide T2 has cytotoxic but no hemolytic activity. | |
| Cliotide T3 | Cliotide T3 was found in Clitoria ternatea. It is not active against Gram-negative bacteria E.coli, K.pneumoniae and P.aeruginosa at concentration up to 100 μM. Cliotide T2 has cytotoxic but no hemolytic activity. | |
| Cliotide T4 | Cliotide T4 was found in Clitoria ternatea. It is active against Gram-negative bacteria E.coli, K.pneumoniae and P.aeruginosa. Cliotide T4 has hemolytic and cytotoxic activity. | |
| Cliotide T7 | Cliotide T7 was found in Clitoria ternatea. It has antimicrobial activity. | |
| CM-3 | CM-3 is a synthetic construct with antibacterial activity. | |
| Cm-p1 | Cm-p1 was found in marine snail Cenchritis muricatus. This peptide demonstrated the capacity to prevent the development of yeasts and filamentous fungi. Otherwise, Cm-p1 displayed no toxic effects against mammalian cells. | |
| CMP-9-fluoresceinyl-NeuAc | CMP-9-fluoresceinyl-NeuAc, is shown to be a suitable donor substrate for sialyltransferase, which belongs to glycosyltransferase family 29. Synonyms: N-Acetyl-9-deoxy-9-[[[(3',6'-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-5-yl)amino]thioxomethyl]amino]-2-(hydrogen 5'-cytidylate) β-Neuraminic Acid; 5-(Acetylamino)-3,5,9-trideoxy-9-[[[(3',6'-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-5-yl)amino]thioxomethyl]amino]-D-glycero-β-D-galacto-2-Nonulopyranosonic Acid 2-(Hydrogen 5'-cytidylate); Spiro[isobenzofuran-1(3H),9'-[9H]xanthene] D-glycero-β-D-galacto-2-nonulopyranosonic acid Deriv. CAS No. 118720-35-7. Molecular formula: C41H43N6O20PS. Mole weight: 1002.85. | |
| CMP-CP | CMP-CP is a non-hydrolytic analogue of CDP. It is commonly used as a starting structure in the synthesis of α/β hydrolysis-resistant tri- and polyphosphates. Synonyms: Cytidine- 5'- O- (α, β- methylene)diphosphate, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 101536-15-6. Molecular formula: C10H17N3O10P2 (free acid). Mole weight: 401.2 (free acid). | |
| CMP-Neu5Ac sodium salt | CMP-Neu5Ac sodium salt, a vital compound in the biomedical sector, is intricately involved in numerous biological processes, aiding in the synthesis of sialylated compounds. Notably, its indispensable role as a substrate for sialyltransferases facilitates the treatment of ailment manifestations characterized by aberrant sialylation. Afflicting individuals are plagued by a range of conditions, including cancer, neurological disorders, and autoimmune diseases, wherein CMP-Neu5Ac sodium salt assumes significance. Synonyms: CMP-NANA; Cytidine 5'-monophospho-b-D-N-acetylneuraminic acid sodium salt; CMP-N-acetylneuraminic acid sodium salt; CMP-Sialic Acid. Grades: 85%. CAS No. 1007117-62-5. Molecular formula: C20H30N4O16P·Na. Mole weight: 636.43. | |
| Cn-AMP1 | Cn-AMP1 is an antimicrobial peptide produced by Cocos nucifera (Coconut palm, green coconut water). It has antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Synonyms: Antimicrobial peptide 1; Ser-Val-Ala-Gly-Arg-Ala-Gln-Gly-Met; Cocos nucifera antimicrobial peptide 1. Grades: >96%. CAS No. 1158169-22-2. Molecular formula: C34H61N13O12S. Mole weight: 876.01. | |
| Cn-AMP2 | Cn-AMP2 is an antimicrobial peptide found in Cocos nucifera (Coconut palm, green coconut water). It has antibacterial activity. Synonyms: Thr-Glu-Ser-Tyr-Phe-Val-Phe-Ser-Val-Gly-Met; Cn-AMP2 (Plant defensin); Antimicrobial peptide 2. Grades: ≥96%. CAS No. 1158169-23-3. Molecular formula: C59H83N11O18S. Mole weight: 1266.43. | |
| Cn-AMP3 | Cn-AMP3 is from Cocos nucifera. It has antimicrobial activity against Gram-positive bacteria B.subtilis (MIC=257 μg/ml) and S.aureus (MIC=274 μg/ml), and against Gram-negative bacteria E.coli (MIC=302 μg/ml) and P.aeruginosa (MIC=259 μg/ml). The activity of this series of peptides is Cn-AMP1 > Cn-AMP2 > Cn-AMP3. | |
| Coagulin | Coagulin is a new antilisterial bacteriocin in the pediocin family of bacteriocins produced by Bacillus coagulans I4. | |
| Coccinin | Coccinin is an antifungal peptide with antiproliferative and HIV-1 reverse transcriptase inhibitory activities from large scarlet runner beans. | |
| Cod beta defensin | Cod beta defensin is a novel beta-defensin antimicrobial peptide in Gadus morhua with stimulatory effect on phagocytic activity. | |
| Coenzyme A S-(2-Ethyl-3-oxobutanoate) | Coenzyme A S-(2-Ethyl-3-oxobutanoate) is an derivative of Coenzyme A, a cofactor in enzymatic acetyl transfer reactions. Molecular formula: C27H44N7O18P3S. Mole weight: 879.6. | |
| Coenzyme A S-Pyrazinecarboxylate Trisodium Salt | Coenzyme A S-Pyrazinecarboxylate is a derivative of Coenzyme A; a cofactor in enzymatic acetyl transfer reactions. It is the source of the phosphopantetheine group that is added as a prosthetic group to proteins such as acyl carrier protein and formyltetrahydrofolate dehydrogenase. Synonyms: S- (2- (3- ( (2R) -4- ( ( ( ( ( ( (2R, 3S, 4R, 5R) -5- (6-Amino-9H-purin-9-yl) -4-hydroxy-3- (phosphonooxy) tetrahydrofuran-2-yl) methoxy) (hydroxy) phosphoryl) oxy) (hydroxy) phosphoryl) oxy) -2-hydroxy-3, 3-dimethylbutanamido) propanamido) ethyl) Pyrazine-2-carbothioate Trisodium Salt. Molecular formula: C26H35N9Na3O17P3S. Mole weight: 939.56. | |
| Coenzyme A Trilithium Salt | A cofactor in enzymatic acetyl transfer reactions. It is the source of the phosphopantetheine group that is added as a prosthetic group to proteins such as acyl carrier protein and formyltetrahydrofolate dehydrogenase. Synonyms: CoA Trilithium Salt; Trilithium Coenzyme A. Grades: 95%. CAS No. 18439-24-2. Molecular formula: C21H33Li3N7O16P3S. Mole weight: 785.33. | |
| Colivelin | Colivelin, a neuroprotective peptide and activator of STAT3, is able to suppress neuronal death and protect neurons against the neurotoxic effects of amyloid β-peptide (1-43) at a concentration of 100 fM in vitro. Uses: Implicated in alzheimer's disease. Synonyms: Ser-Ala-Leu-Leu-Arg-Ser-Ile-Pro-Ala-Pro-Ala-Gly-Ala-Ser-Arg-Leu-Leu-Leu-Leu-Thr-Gly-Glu-Ile-Asp-Leu-Pro; L-seryl-L-alanyl-L-leucyl-L-leucyl-L-arginyl-L-seryl-L-isoleucyl-L-prolyl-L-alanyl-L-prolyl-L-alanyl-glycyl-L-alanyl-L-seryl-L-arginyl-L-leucyl-L-leucyl-L-leucyl-L-leucyl-L-threonyl-glycyl-L-alpha-glutamyl-L-isoleucyl-L-alpha-aspartyl-L-leucyl-L-proline. Grades: ≥95%. CAS No. 867021-83-8. Molecular formula: C119H206N32O35. Mole weight: 2645.13. | |
| Colutellin-A | Colutellin A is an immunosuppressive peptide from Colletotrichum dematium. It has antifungal activity against S.sclerotiorum (MIC=32.4 μg/ml after 288 hours) and B.cinerea (MIC=10.8 μg/ml after 288 hours), and weak antifungal activity against F.solani, A.fumigatus and G.candidum. And it lacks antifungal activity against P.ultimum, T.viride and R.solani. | |
| Combi-1 | Combi-1 is a synthetic construct with antimicrobial activity. | |
| Combi-2 | Combi-2 is a synthetic construct with antibacterial activity. | |
| Compstatin control peptide | Compstatin control peptide is a kind of control peptide for compstatin. It is a complement inhibitor. Grades: >98%. CAS No. 301544-78-5. Molecular formula: C66H101N23O17. Mole weight: 1488.67. | |
| COMU | COMU is used as an efficient coupling agent in phosphonamidation reactions; used as coupling reagent in the synthesis of solid phase peptide. Synonyms: (1-Cyano-2-ethoxy-2-oxoethylidenaminooxy) dimethylaminomorpholinocarbenium Hexafluorophosphate; (1-Cyano-2-ethoxy-2-oxoethylideneaminooxy)-dimethylamino-morpholino-carbenium hexafluorophosphate; 4-{{[(1-Cyano-2-ethoxy-2-oxoethylidene)amino]oxayl] (dimethylamino)methylene]-hexafluorophosphate; COMU(R); Elagolix intermediate 13. Grades: > 98 % (HPLC). CAS No. 1075198-30-9. Molecular formula: C12H19F6N4O4P. Mole weight: 428.27. | |
| Conantokin-R | Conantokin-R is a potent and non-competitive NMDA receptor antagonist with IC50 value of 93 nM. It also has NR2 subunit selectivity. It inhibits inward currents evoked by NMDA in central nervous system neurons. It shows broad antiparkinsonian and anticonvulsant activity in vivo. Synonyms: Conantokin R; 202925-60-8; conantokin-RAKOS024457444; CID 90488802. Grades: >98%. CAS No. 202925-60-8. Molecular formula: C127H201N35O49S3. Mole weight: 3098.4. | |
| Conantokin-T | Conantokin-T is a non-competitive NMDA receptor antagonist with IC50 value of 0.4 μM. It inhibits Ca2+ influx and glutamate-induced toxicity in central nervous system neurons. It has age-dependent physiological effects. It induces hyperactivity in older mice and a sleep-like state in young mice. Uses: Excitatory amino acid antagonists. Synonyms: Conantokin t. Grades: >98%. CAS No. 127476-26-0. Molecular formula: C110H175N31O45S. Mole weight: 2683.8. | |
| Conolysin-Mt2 | Conolysin-Mt2 was found in Weasel cone (Conus mustelinus). It has antibacterial activity. | |
| Coprisin | Copris tripartitus is the novel 43-residue, insect defensin-like peptide coprisin isolated from the dung beetle. Copris tripartitus is a potent antibiotic with bacterial cell selectivity, exhibiting antimicrobial activities against Gram-positive and Gram-negative bacteria without exerting hemolytic activity against human erythrocytes. | |
| Corticostatin 1 | Corticostatin 1 is from Oryctolagus cuniculus. It has microbicidal activity and inhibits corticotropin (ACTH) stimulated corticosterone production. Synonyms: Antiadrenocorticotropin peptide I. | |
| Corticostatin-3 precursor | Corticostatin-3 precursor is isolated from Oryctolagus cuniculus. It has antibacterial, antifungal and antiviral activities. | |
| Corticostatin-4 precursor | Corticostatin-4 precursor is isolated from Oryctolagus cuniculus. It has antifungal and antiviral activities. | |
| Corticostatin-6 | Corticostatin-6 is from Oryctolagus cuniculus. It has microbicidal activity and inhibits corticotropin (ACTH) stimulated corticosterone production. | |
| Corticostatin-related peptide LCRP | Corticostatin-related peptide LCRP is isolated from Petromyzon marinus. It may inhibit corticotropin (ACTH) stimulated steroidogenesis and the microbial actions of the corticostatins. | |
| Corticostatin-related peptide RK-1 | Corticostatin-related peptide RK-1 is isolated from Oryctolagus cuniculus. It has antimicrobial activity against E.coli and activates ion channel activity. | |
| Cortistatin 14, human, rat | Cortistatin 14 is an endogenous neuropeptide similar to somatostatin-14 in structure and function. It is mainly expressed in the cortex and hippocampus. It shows potency at all somatostatin receptors, but prevents somatostatin-14 binding. It binds to the growth hormone secretagog receptor (GHS-R1a). It displays sleep-modulating and neuronal depressant properties in vivo. Synonyms: CST-14, human, rat; Pro-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Ser-Ser-Cys-Lys (Disulfide bridge: Cys2-Cys13); Corticostatin-14; L-prolyl-L-cysteinyl-L-lysyl-L-asparagyl-L-phenylalanyl-L-phenylalanyl-L-tryptophyl-L-lysyl-L-threonyl-L-phenylalanyl-L-seryl-L-seryl-L-cysteinyl-L-lysine (2->13)-disulfide; N2-{[(4R, 7S, 10S, 13S, 16S, 19S, 22S, 25S, 28S, 31S, 34S, 37R)-19, 34-Bis(4-aminobutyl)-31-(2-amino-2-oxoethyl)-13, 25, 28-tribenzyl-16-(1-hydroxyethyl)-7, 10-bis(hydroxymethyl)-22-(1H-indol-3-ylmethyl)-6, 9, 12, 15, 18, 21, 24, 27, 30, 33, 36-undecaoxo-37-(L-prolylamino)-1, 2-dithia-5, 8, 11, 14, 17, 20, 23, 26, 29, 32, 35-undecaazacyclooctatriacontan-4-yl]carbonyl}-L-lysine. Grades: ≥95%. CAS No. 193829-96-8. Molecular formula: C81H113N19O19S2. Mole weight: 1721.01. | |
| COT Serinol Phosphoramidite | COT Serinol Phosphoramidite is an indispensable compound, facilitating the intricate research and development of bespoke nucleosides and nucleotides. Profoundly pivotal, this compound assumes a critical function in the development of tailored oligonucleotides, particularly pertaining to the research of hereditary afflictions and the establishment of targeted pharmaceutical transport mechanisms. Synonyms: 3-Dimethoxytrityloxy-2- (3- (3-cyclooctatetraenylpropanamido) propanamido) propyl-1-O- (2-cyanoethyl) - (N, N-diisopropyl) -phosphoramidite. Molecular formula: C47H59N4O7P. Mole weight: 822.97. | |
| CPF-AM1 | CPF-AM1 is a novel insulinotropic peptide from the skin secretion of the clawed frog, Xenopus amieti. Synonyms: caerulein-precursor fragment AM1. | |
| CPF-AM4 | The source of CPF-AM4 is the octoploid frog Xenopus amieti (Pipidae). CPF-AM4 has antibacterial activity against Escherichia coli and Staphylococcus aureus. Grades: >98% by HPLC. | |
| CPF-B1 | CPF-B1 is produced by Xenopus borealis. The peptide with the greatest potential for development into a therapeutically valuable anti-infective agent was CPF-B1 with MIC=5 microM against E. coli, MIC=5 microM against S. aureus, and MIC=25 microM against Candida albicans, and low hemolytic activity against human erythrocytes (LC(50)>200 microM). Synonyms: GLGSLLGKAFKIGLKTVGKMMGGAPREQ; CPF-B1. Molecular formula: C126H218N36O34S2. Mole weight: 2845.4. | |
| CPF-C1 | CPF-C1 is a typical cationic antimicrobial peptide that was originally isolated from the tetraploid frog Xenopus clivii. CPF-C1 has potent antimicrobial activity against both sensitive and multidrug-resistant bacteria. | |
| CPF-L1 | CPF-L1 was found in Xenopus lenduensis. It has antibacterial activity. | |
| CPF-L2 | CPF-L2 was found in Xenopus lenduensis. It has antibacterial activity. | |
| CPF-P2 | CPF-P2 has antibacterial activity against E. coli (MIC=25 uM) and S. aureus (MIC= 6 uM). The source of CPF-P2 is skin secretions, Xenopus petersii, Africa. Grades: >95% by HPLC. | |
| CPF-P3 | CPF-P3 has antibacterial activity against E. coli (MIC=12.5 uM) and S. aureus (MIC=6 uM). The source of CPF-P3 is skin secretions, Xenopus petersii, Africa. Grades: >98% by HPLC. | |
| CPF-P4 | CPF-P4 has antibacterial activity against E. coli (MIC=25 uM) and S. aureus (MIC=6 uM). The source of CPF-P4 is skin secretions, Xenopus petersii, Africa. Grades: >96% by HPLC. | |
| CPF-P5 | CPF-P5 was found in Xenopus petersii. It has antibacterial activity. | |
| CPF-PG1 | CPF-PG1 from X. pygmaeus combined high antimicrobial potency against Staphylococcus aureus (MIC=6 μM) with relatively low hemolytic activity (LC(50)=145 μM). | |
| CPF-SE1 | The source of CPF-SE1 is Cameroon Clawed Frog, the tetraploid frog Silurana epitropicalis SE1, Africa. It moderately active against E. coli (MIC=40 uM) and highly active against S. aureus MRSA (MIC=2.5 uM). | |
| CPF-SE2 | The source of CPF-SE2 is Cameroon Clawed Frog, the tetraploid frog Silurana epitropicalis SE1, and Silurana paratropicalis, Africa. It moderately active against E. coli and highly active against S. aureus and MRSA (MIC=2.5 uM). | |
| CPF-St4 | CPF-St4 was found in the African clawed frog Silurana tropicalis. It is active against E. coli (MIC 2-4 uM), P. aeruginosa (MIC 4-8 uM), S. aureus (MIC 1 uM), M. luteus (MIC 0.5 uM), and S. cerevisiae (MIC 16 uM). CPF-St4 is also toxic to erythrocytes (HC50 64 uM) and T-lymphocytes (IC50 2 uM). | |
| CPF-St5 | CPF-St5 was found in the African clawed frog Silurana tropicalis. It exerts antimicrobial effects against Gram-positive bacteria, Gram-negative bacteria, and fungi. | |
| CPF-St6 | CPF-St6 was found in the African clawed frog Silurana tropicalis. It exerts antimicrobial effects against Gram-positive bacteria, Gram-negative bacteria, and fungi. | |
| CPF-St7 | CPF-St7 was found in the African clawed frog Silurana tropicalis. It exerts antimicrobial effects against Gram-positive bacteria, Gram-negative bacteria, and fungi. | |
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