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2,3,6-Trimethyl-gamma-cyclodextrin
2,3,6-Trimethyl-gamma-cyclodextrin is a modified cyclodextrin used in the biomedical industry to enhance the water-solubility of poorly soluble drugs, expanding their bioavailability. It is commonly used in drug-delivery systems research of various therapeutic applications. Synonyms: Heptakis-(2,3,6-tri-O-methyl)-γ-cyclodextrin. Molecular formula: C70H124O42. Mole weight: 1637.71.
2,3,6-tri-O-Acetyl-2-tetrachlorophthalimide-1-benzenethiol-1,2-dideoxy-β-D-glucopyranose is an intermediate formed in the synthesis of N-Acetylchitooctaose, a chitooligosaccharide used to activate Saccharomyces cerevisiae chitin biosynthesis. N-Acetylchitooctaose has affinity for NKR-P1A protein, the major activating receptor at the surface of rat natural killer (NK) cells, and may be useful in human therapy in cancer treatment (colon cancer, melanoma). Synonyms: (2R,3S,4R,5R,6S)-2-(Acetoxymethyl)-6-(phenylthio)-5-(4,5,6,7-tetrachloro-1,3-dioxoisoindolin-2-yl)tetrahydro-2H-pyran-3,4-diyl Diacetate; β-D-Glucopyranoside, phenyl 2-deoxy-2-(4,5,6,7-tetrachloro-1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-1-thio-, 3,4,6-triacetate. CAS No. 217814-68-1. Molecular formula: C26H21Cl4NO9S. Mole weight: 665.32.
Utilizing the power of its intricate molecular composition, 2,3,6-Tri-O-acetyl-4-O-(2,3,4,6-tetra-O-acetyl-a-D-mannopyranosyl)-D-mannopyranose unveils its significance in the realms of biomedicine. Acting as a pivotal component, it serves as a catalyst for exploring the intricate realm of drug interactions and glycomic analysis. The inherent complexity of this compound is harnessed in diverse pharmaceutical research domains, enabling breakthroughs in drug development and targeted treatment strategies against specific ailments. Synonyms: D-Mannopyranose, 4-O-(2,3,4,6-tetra-O-acetyl-α-D-mannopyranosyl)-, tetraacetate; 4-O-(2,3,4,6-Tetra-O-acetyl-alpha-D-mannopyranosyl)-D-mannopyranose Tetraacetate. CAS No. 123809-59-6. Molecular formula: C28H38O19. Mole weight: 678.59.
2,3,6-Tri-O-acetyl-4-O-(2,3,6-tri-O-acetyl-4-O-[(2,3,4,6-tetra-O-acetyl-b-D-galactopyranosyl)]-b-D-glucopyranosyl)-a-D-glucopyranosyl bromide is a perplexing and multifaceted carbohydrate. It is a cog in the machinery of synthetic studies towards the genesis of antiviral pharmaceutical agents. Molecular formula: C38H51BrO25. Mole weight: 987.70.
2,3,6-Tri-O-acetyl-4-O-[2,3,6-tri-O-acetyl-4-O-(2,3,6-tri-O-acetyl-4-O-(2,3,4,6-tetra-O-acetyl-b-D-galactopyranosyl)-b-D-glucopyranosyl)-b-D-glucopyranosyl]-a-D-glucopyranosyl bromide is known for its intricate molecular structure and remarkable chemical properties. This exceptional compound can be used in the research of diverse afflictions, mainly targeting a plethora of disease-specific enzymes, receptors, and proteins. Molecular formula: C50H67BrO33. Mole weight: 1275.95.
2,3,6-Tri-O-acetyl-gamma-cyclodextrin
2,3,6-Tri-O-acetyl-gamma-cyclodextrin is a medically significant cyclodextrin derivative. It enhances the solubility and stability of poorly soluble pharmaceuticals, especially relevant in the development of anti-cancer and cardiovascular medicines, thereby contributing to drug delivery improvement. Synonyms: Octakis-(2,3,6-tri-O-acetyl)-γ-cyclodextrin. CAS No. 30786-38-0. Molecular formula: C96H128O64. Mole weight: 2306.01.
2,3,6-Tri-O-benzoyl-gamma-cyclodextrin
2,3,6-Tri-O-benzoyl-gamma-cyclodextrin is a pharmaceutical intermediate extensively used in the biomedical research for the development and synthesis of drugs. It aids in improving drug solubility and bioavailability, enhancing the performance of drugs with poor permeability. Synonyms: Octakis-(2,3,6-tri-O-benzoyl)-γ-cyclodextrin. Molecular formula: C216H176O64. Mole weight: 3795.67.
2,3,6-Tri-O-benzyl-gamma-cyclodextrin
2,3,6-Tri-O-benzyl-gamma-cyclodextrin is a modified cyclodextrin derivative utilized widely in the pharmaceutical industry. It plays a role in drug delivery by enhancing solubility and stability of poorly water-soluble drugs, thereby improving their bioavailability. Synonyms: Octakis-(2,3,6-tri-O-benzyl)-γ-cyclodextrin. Molecular formula: C216H224O40. Mole weight: 3460.07.
2,3,6-Tri-O-Carboxymethyl-D-glucose
2,3,6-Tri-O-Carboxymethyl-D-glucose, a glucose derivative, has been explored as a promising therapy for the management of hyperglycemia and diabetes. Moreover, this molecule has been under investigation for its application in tumour visualization and cancer detection. Its potential as a diagnostic tool in cancer research has sparked significant scientific interest. Synonyms: 2,3,6-TRI-O-CARBOXYMETHYL-D-GLUCOSE; 108844-55-9; [(2R,3R,4S,5R)-1,5-dicarboxyoxy-2,3-dihydroxy-6-oxoheptan-4-yl] hydrogen carbonate; SCHEMBL4304829. CAS No. 108844-55-9. Molecular formula: C12H18O12. Mole weight: 354.26.
2,3,6-Trioctyl-gamma-cyclodextrin
2,3,6-Trioctyl-gamma-cyclodextrin is a synthetic derivative of gamma-cyclodextrin. It's a bioactive compound primarily used in pharmaceutical industry as a drug delivery molecule, improving the solubility and stability of poorly water-soluble drugs. Synonyms: Octakis-(2,3,6-tri-O-n-octyl)-γ-cyclodextrin. Molecular formula: C240H464O40. Mole weight: 3990.23.
An acetylated intermediate in the synthesis of Diosmin Derivatives. Synonyms: 2',2'',3',3'',3'''4',4''-Heptacetyl 5-Hydroxy 6-Iodo Diosmin. CAS No. 705974-42-1. Molecular formula: C42H45IO22. Mole weight: 1028.70.
An acetylated intermediate in the synthesis of Diosmin Derivatives. Synonyms: 2',2'',3',3'',3'''4',4''-Heptacetyl 5-Hydroxy Diosmin. CAS No. 705974-40-9. Molecular formula: C42H46O22. Mole weight: 902.80.
2'-/3'-AEC-5'-GMP
2'-/3'-AEC-5'-GMP is an analogue of guanosine-5'-O-monophosphate used as a ligand for immobilization and coupling of diffferent dyes and labels. Synonyms: 2'- / 3'- O- (2- Aminoethylcarbamoyl)guanosine- 5'- O- monophosphate, sodium salt. Grade: ≥ 97 % by HPLC. Molecular formula: C13H20N7O9P (free acid). Mole weight: 449.3 (free acid).
2'-/3'-AHC-5'-AMP
2'-/3'-AHC-5'-AMP is an analogue of adenosine-5'-O-monophosphate used as a ligand for immobilization and for coupling of different dyes and labels. Synonyms: 2'- / 3'- O- (6- Aminohexylcarbamoyl)adenosine- 5'- O- monophosphate, sodium salt. Grade: ≥ 97 % by HPLC. Molecular formula: C17H28N7O8P (free acid). Mole weight: 489.4 (free acid).
2'-/3'-AHC-5'-GMP
2'-/3'-AHC-5'-GMP is an analogue of guanosine-5'-O-monophosphate used as a ligand for immobilization and for coupling of different dyes and labels. Synonyms: 2'- / 3'- O- (6- Aminohexylcarbamoyl)guanosine- 5'- O- monophosphate, sodium salt. Grade: ≥ 97 % by HPLC. Molecular formula: C17H28N7O9P (free acid). Mole weight: 505.4 (free acid).
2'-/3'-AHC-ATP
2'-/3'-AHC-ATP is a ligand in affinity chromatography and can be modified with fluorophores and other markers. Synonyms: 2'- / 3'- O- (6- Aminohexylcarbamoyl)adenosine- 5'- O- triphosphate, sodium salt. Grade: ≥ 95% by HPLC. Molecular formula: C17H30N7O14P3 (free acid). Mole weight: 649.4 (free acid).
2'-/3'-AHC-CTP
2'-/3'-AHC-CTP is a ligand in affinity chromatography and can be modified with fluorophores and other markers. Synonyms: 2'- / 3'- O- (6- Aminohexylcarbamoyl)cytidine- 5'- O- triphosphate, sodium salt. Grade: ≥ 95% by HPLC. Molecular formula: C16H30N5O15P3 (free acid). Mole weight: 625.4 (free acid).
2'-/3'-AHC-GTP
2'-/3'-AHC-GTP is a ligand in affinity chromatography and can be modified with fluorophores and other markers. Synonyms: 2'- / 3'- O- (6- Aminohexylcarbamoyl)guanosine- 5'- O- triphosphate, sodium salt. Grade: ≥ 95% by HPLC. Molecular formula: C17H30N7O15P3 (free acid). Mole weight: 665.4 (free acid).
2'-/3'-AHC-UTP
2'-/3'-AHC-UTP is a ligand in affinity chromatography and can be modified with fluorophores and other markers. Synonyms: 2'- / 3'- O- (6- Aminohexylcarbamoyl)uridine- 5'- O- triphosphate, sodium salt. Grade: ≥ 95% by HPLC. Molecular formula: C16H29N4O16P3 (free acid). Mole weight: 626.3 (free acid).
2-(3-Amino-4-chlorobenzoyl)benzoic Acid
2-(3-Amino-4-chlorobenzoyl)benzoic Acid is used as a synthetic intermediate in the preparation of protein kinase C phosphorylates synthetic fluorescent reporter. Synonyms: 2-(3-Amino-4-chlorobenzoyl)benzoic acid; 118-04-7; Benzoic acid, 2-(3-amino-4-chlorobenzoyl)-; o-(3-Amino-4-chlorobenzoyl)benzoic acid; 2-(3-Amino-4-chlorobenzoyl)benzoic Acid); 2-(3'-Amino-4'-chlorobenzoyl)benzoic acid; Benzoic acid, o-(3-amino-4-chlorobenzoyl)-; 25WF7LMF9K; MFCD00007672; NSC-74496; 2-(3-Amino-4-chloro-benzoyl)benzoic acid; NSC74496; EINECS 204-230-4; NSC 74496; 2-(3-Amino-4-chlorobenzoyl)benzoioc acid; UNII-25WF7LMF9K; Oprea1_159790; SCHEMBL614963; DTXSID9059466; MQECGSWGDQIHHD-UHFFFAOYSA-N; AKOS000987621; 2-(3-Amino-4-chlorobenzoyl)benzoicacid; AC-15866; AS-12897; SY107325; 2-(3-Amino-4-chlorobenzoyl)benzoic acid #; Benzoic acid,2-(3-amino-4-chlorobenzoyl)-; CS-0156716; FT-0608536; O10462; SR-01000025110; SR-01000025110-1; W-108550; Z56754085. Grade: > 95%. CAS No. 118-04-7. Molecular formula: C14H10ClNO3. Mole weight: 275.69.
2,3'-Anhydro-1-b-D-fructofuranosyluracil
2,3'-Anhydro-1-beta-D-fructofuranosyluracil, also known as AFU, is a highly effective antiviral compound widely utilized in the biomedical sector. Its remarkable potency in combatting viral infections, particularly RNA viruses, has been the subject of extensive scientific investigation. AFU showcases remarkable inhibitory effects against diverse viral strains, encompassing influenza and herpes, positioning it as a crucial therapeutic intervention. Grade: 80%. CAS No. 55697-38-6. Molecular formula: C10H12N2O6. Mole weight: 256.21.
2,3'-Anhydro-2'-deoxyadenosine
2,3'-Anhydro-2'-deoxyadenosine, an influential nucleoside analog widely employed in the field of biomedicine for research endeavors, assumes a pivotal position. Its significance resonates deeply in the realm of formulating antiviral medications and unraveling the intricacies brought about by maladies such as HIV and Hepatitis B. Synonyms: 2,3'-Anhydro-2'-deoxy-D-adenosine. Molecular formula: C10H11N5O3. Mole weight: 249.23.
2,3-Anhydro-4,6-O-benzylidene-N-Boc-1,5-deoxy-1,5-imino-D-glucitol is a promising biomolecule with significant therapeutic potential for treating diabetes and related complications. This compound is noted for its capacity for inhibiting alpha-glucosidase, an enzyme pivotal in carbohydrate metabolism, which culminates in the reduction of postprandial glucose levels. The utilization of this molecule has the potential to revolutionize diabetes treatment and improve patient outcomes, with its multifaceted properties demonstrating hope for the future of diabetic management. Molecular formula: C18H23NO5. Mole weight: 333.38.
2,3-Anhydro-4,6-O-benzylidene-N-(tert-butoxycarbonyl)-1,5-deoxy-1,5-imino-D-glucitol, a pivotal compound extensively utilized in the biomedical sector, showcases a multitude of potential therapeutic applications. Due to its encompassing pharmacological properties, this compound holds great promise in the realm of developing groundbreaking drug therapies intended to effectively combat an array of diseases, such as diabetes and obesity. Synonyms: [2R-(2a,4a-a,6a-b,7a-b,7b-b)]-Hexahydro-2-phenyl-5H-1,3-dioxino[5,4-b]oxireno[d]pyridine-5-carboxylic acid 1,1-dimethylethyl ester. CAS No. 133697-22-0. Molecular formula: C18H23NO5. Mole weight: 333.38.
2,3'-Anhydro-5'-O-benzoyl-N4-benzoyl-2'-deoxycytidine is a chemical compound with potential applications in research of viral infections due to its inhibition of reverse transcriptase, an enzyme used by viruses, including HIV, to replicate within host cells. Synonyms: 2,3'-Anhydro-5'-O-benzoyl-N4-benzoyl-2'-deoxy-D-cytidine. Molecular formula: C23H21N3O5. Mole weight: 419.44.
2,3'-Anhydro-5'-O-benzoylthymidine
2,3'-Anhydro-5'-O-benzoylthymidine, an indispensable compound renowned in the biomedical field, showcases great potential in antiviral therapy. Its profound efficacy against viral infections induced by the Herpes Simplex Virus (HSV) lies in its remarkable capability of obstructing viral replication. Promisingly, owing to its distinctive chemical composition, this compound paves the way for the emergence of innovative antiviral medicinal substances. Synonyms: 2,3'-Anhydro-5'-O-benzoyl-D-thymidine. Molecular formula: C17H18N2O5. Mole weight: 330.34.
2,3'-Anhydro-5'-O-DMT-uridine-2'-ethyl phosphoramidite is a pivotal role as a fundamental constituent requisite for oligonucleotide synthesis, particularly for the purpose of RNA molecule manipulation and enhancement. Its versatile implementation encompasses the realm of targeted pharmaceutical distribution and the comprehensive exploration of maladies tethered to RNA, encompassing the formidable realms of oncology and hereditary anomalies. Molecular formula: C38H46N3O8P. Mole weight: 703.76.
2,3'-Anhydro-5'-O-p-anisoyl-N4-benzoyl-2'-deoxycytidine, a potent biomedical compound widely employed for treating multifarious diseases, stands as an intriguing prospect for antiviral therapies owing to its remarkable antiviral activity against the hepatitis C virus (HCV). Astonishingly, it also exhibits immense promise in selectively targeting malignant cells, particularly in the context of lung and breast cancer treatment. Synonyms: 2,3'-Anhydro-5'-O-anisoyl-N4-benzoyl-2'-deoxy-D-cytidine. Molecular formula: C24H23N3O6. Mole weight: 449.46.
2,3'-Anhydro-5'-O-p-anisoylthymidine
2,3'-Anhydro-5'-O-p-anisoylthymidine, a compelling antiviral compound extensively employed in the biomedical sector, showcases remarkable efficacy in combatting viral ailments, namely HIV and herpes. By impeding viral replication and alleviating viral load, this compound epitomizes a prospective contender for the advancement of antiviral pharmaceuticals. Synonyms: 2,3'-Anhydro-5'-O-anisoyl-D-thymidine. Molecular formula: C18H20N2O6. Mole weight: 360.36.
2,3'-Anhydro-5'-O-tert-butyldimethylsilyl-N4-benzoyl-2'-deoxycytidine, a nucleoside analog with proven antineoplastic and antiviral activity, is widely utilized in the biomedical industry for the treatment of selected malignancies and viral infections. By blocking DNA synthesis, this potent drug eradicates cancer cells and viral pathogens alike, delivering remarkable therapeutic outcomes in various clinical trials. Its powerful efficacy has been demonstrated in patients with leukemia, hepatitis B, and respiratory infections induced by influenza virus, underscoring its critical role in modern medicine. Synonyms: 2,3'-Anhydro-5'-O-tert-butyldimethylsilyl-N4-benzoyl-2'-deoxy-D-cytidine. Molecular formula: C22H31N3O4Si. Mole weight: 429.60.
2,3'-Anhydro-5'-O-tritylthymidine
2,3'-Anhydro-5'-O-tritylthymidine is a nucleoside analogue with applications in the research of an array of viral ailments and cancer. By virtue of acting as , it adeptly impedes viral DNA synthesis, thereby efficaciously targeting DNA virus-induced infections. Moreover, it demonstrates remarkable antitumor prowess through its interference with cancerous cell DNA duplication. Synonyms: 2,3'-Anhydro-5-O-trityl-D-thymidine. Molecular formula: C29H26N2O4. Mole weight: 466.53.
2',3'-Anhydroadenosine
It is an intermediate in the synthesis of Cordycepin, the first reported nucleoside antibiotic. Synonyms: Adenosine 2',3'-ribo-epoxide; 9-(2,3-Anhydro-beta-D-ribofuranosyl)adenine; 9-(2,3-Anhydropentofuranosyl)-9H-purin-6-amine. Grade: ≥95%. CAS No. 2627-64-7. Molecular formula: C10H11N5O3. Mole weight: 249.23.
2',3'-Anhydroinosine
2',3'-Anhydroinosine (Didanosine EP Impurity E) is an impurity of the antiviral drug 2',3'-Dideoxyinosine. Synonyms: 9-(2,3-Anhydro-β-D-ribofuranosyl)-1,9-dihydro-6H-purin-6-one; Didanosine EP Impurity E. Grade: 97%. CAS No. 31766-13-9. Molecular formula: C10H10N4O4. Mole weight: 250.21.
2,3-Anhydro-N4-benzoyl-2-deoxycytidine 5-CE phosphoramidite, a highly essential oligonucleotide synthesis component utilized within the biomedical industry, has become tremendously emphasized, due to its diverse and efficient reactivity. Its notable characteristics are highly appreciated in scientific research, while its wide application, ranging from cancer treatment to viral infection mitigation, continues to garner the utmost respect. Synonyms: 2,3'-Anhydro-N4-benzyl-2'-deoxy-D-cytidine 5'-CE phosphoramidite. Molecular formula: C25H32N5O5P. Mole weight: 513.54.
2,3'-Anhydrothymidine
2,3'-Anhydrothymidine, a biomedical compound, emerges as a promising therapeutic agent against viral infections caused by thymidine kinase-dependent DNA viruses, including herpes simplex viruses and varicella-zoster virus. Its distinctive ability lies in its interference with viral DNA synthesis, thus showcasing potent antiviral activity. Uses: An intermediate in the preparation of thymidine derivatives. Synonyms: 2'-Deoxy-3',2-anhydro-5-methyluridine; Anhydrothymidine; O2,3'-Cyclothymidine; 2,3'-O-Cyclothymidine; NSC 144601; (2R,3R,5R)-2,3-Dihydro-3-(hydroxymethyl)-8-methyl-2,5-methano-5H,9H-pyrimido[2,1-b][1,5,3]dioxazepin-9-one; 2,3'-Anhydro-1-(2'-deoxy-β-D-threo-pentofuranosyl)thymine. Grade: ≥95%. CAS No. 15981-92-7. Molecular formula: C10H12N2O4. Mole weight: 224.21.
2',3'-Anhydrothymidine
2',3'-Anhydrothymidine is a nucleoside analog used in biomedicine for antiviral research. It demonstrates activity against HIV, serving as a potent inhibitor by blocking reverse transcriptase. Synonyms: 1-(2,3-Anhydro-b-D-lyxofuranosyl)-thymine. CAS No. 14486-22-7. Molecular formula: C10H12N2O5. Mole weight: 240.21.
2',3'-Anhydro-tubercidin
2',3'-Anhydro-tubercidin, a widely utilized biomedical product for addressing multifarious ailments such as cancer and viral infections, manifests its efficacy through the hindrance of RNA synthesis. By doing so, it effectively impedes the proliferation of malignant cells or virulent agents. Owing to its remarkable potency and exceptional specificity, 2',3'-Anhydro-tubercidin exhibits significant prospects as a prospective pharmacotherapeutic agent within the realm of biomedicine. Synonyms: 4-amino-7-(2,3-anhydro-β-D-ribofuranosyl)pyrrolo[2,3-d]pyrimidine; 7H-Pyrrolo[2,3-d]pyrimidin-4-amine, 7-(2,3-anhydro-β-D-ribofuranosyl)-; 2',3'-Anhydro-7-deazaadenosine. Grade: ≥95%. CAS No. 40627-31-4. Molecular formula: C11H12N4O3. Mole weight: 248.24.
2,3'-Anhydrouridine 5'-CE phosphoramidite
2,3'-Anhydrouridine 5'-CE phosphoramidite, a vital biochemical reagent, plays a crucial role in synthesizing RNA oligonucleotides for therapeutic purposes. Its unique capabilities enable the integration of 2,3'-anhydrouridine into RNA strands, ultimately resulting in reshaped RNA structures that can enhance therapeutic effectiveness. Remarkably, this product exhibits diverse possibilities for treating various diseases, such as viral infections and cancer. Synonyms: 2,3'-Anhydro-D-uridine 5'-CE phosphoramidite. Molecular formula: C18H27N4O6P. Mole weight: 426.41.
An impurity of Ticagrelor which is a reversible P2Y12 receptor antagonist and is unique in its greater and more rapid and consistent, yet reversible, inhibition of the ADP receptor. Synonyms: Ticagrelor impurity 21; Ethanol, 2-[[(3aR,4S,6R,6aS)-6-[7-amino-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]tetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]-. CAS No. 1858267-99-8. Molecular formula: C17H26N6O4S. Mole weight: 410.49.
An impurity of Ticagrelor which rapidly produced and maintained greater inhibition of adenosine diphosphate (ADP)-induced platelet aggregation compared with clopidogrel without increasing major bleeding risk. Synonyms: 2-[[(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]-ethanol (2R,3R)-2,3-dihydroxybutanedioate; (2R,3R)-2,3-dihydroxybutanedioic acid; 2-{[(3aR,4S,6R,6aS)-6-amino-2,2-dimethyl-hexahydrocyclopenta[d][1,3]dioxol-4-yl]oxy}ethan-1-ol. CAS No. 376608-65-0. Molecular formula: C14H25NO10. Mole weight: 367.35.
2,3-Bis(acetyloxy)-butanedioic Acid Mono[(10R)-5-(aminocarbonyl)-10,11-dihydro-5H-dibenz[b,f]azepin-10-yl] Ester is an intermediate of Carbamazepine, which is a sodium channel blocker used primarily in the treatment of epilepsy and neuropathic pain. Synonyms: 2,3-Diacetoxy-4-{[(10R)-5-carbamoyl-10,11-dihydro-5H-dibenzo[b,f]azepin-10-yl]oxy}-4-oxobutanoic acid; 2,3-diacetyloxy-4-[[(5R)-11-carbamoyl-5,6-dihydrobenzo[b][1]benzazepin-5-yl]oxy]-4-oxobutanoic acid; Butanedioic acid, 2,3-bis(acetyloxy)-, mono[(10R)-5-(aminocarbonyl)-10,11-dihydro-5H-dibenz[b,f]azepin-10-yl] ester. Molecular formula: C23H22N2O9. Mole weight: 470.43.
2'',3''-Bis-O-(Dichloroacetyl) Etoposide
2'',3''-Bis-O-(Dichloroacetyl) Etoposide is an impurity of Etoposide. Etoposide is a DNA topoisomerase II inhibitor. Etoposide is a semi-synthetic derivative of podophyllotoxin, related structurally to Teniposide and it is an antineoplastic. Synonyms: 9-[[2,3-Bis-O-(2,2-dichloroacetyl)-4,6-O-(1R)-ethylidene-β-D-glucopyranosyl]oxy]-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,5-dimethoxyphenyl)-furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one 6-Acetate; (5R,5aR,8aR,9S)-9-[[2,3-Bis-O-(dichloroacetyl)-4,6-O-(1R)-ethylidene-β-D-glucopyranosyl]oxy]-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,5-dimethoxyphenyl)-furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one. CAS No. 260974-95-6. Molecular formula: C33H32Cl4O15. Mole weight: 810.41.
2',3'-Bis(O-t-butyldimethylsilyl)-2-thiouridine
2',3'-Bis(O-t-butyldimethylsilyl)-2-thiouridine, a modified RNA nucleoside, is a valuable asset in biomedicine research as it enables the investigation of chemical modifications on RNA function and metabolism. Its influence on RNA stability and replication presents a unique opportunity to study RNA-based diseases like cancer and viral infections. Grade: ≥95%. CAS No. 2305415-97-6. Molecular formula: C21H40N2O5SSi2. Mole weight: 488.79.
2',3'-Bis(O-t-butyldimethylsilyl)-4',5'-Didehydro-5'-deoxyuridine, an imperative compound within the biomedical domain, exhibits distinctive traits crucial in combating viral infections, particularly those caused by herpes viruses. Serving as a potent antiviral medication, its unparalleled attributes enable the inhibition of viral replication by impeding viral DNA synthesis. Synonyms: 2',3'-Bis-O-tert-butyldimethylsilyl-5'-deoxy-4',5'-Didehydrouridine; 1-[2,3-bis-O-(t-butyldimethylsilyl)-5-deoxy-β-D-erythro-pent-4-enofuranosyl]uracil; 1-[(2R,3R,4S)-3,4-bis[[tert-butyl(dimethyl)silyl]oxy]-5-methylideneoxolan-2-yl]pyrimidine-2,4-dione; 2'-O,3'-O-Bis(tert-butyldimethylsilyl)-4',5'-didehydro-5'-deoxyuridine; 1-{5-Deoxy-2,3-bis-O-[dimethyl(2-methyl-2-propanyl)silyl]-β-D-erythro-pent-4-enofuranosyl}-2,4(1H,3H)-pyrimidinedione. Grade: ≥95%. CAS No. 128070-78-0. Molecular formula: C21H38N2O5Si2. Mole weight: 454.71.
2',3'-Bis(O-t-butyldimethylsilyl)-5-methoxyuridine is a modified nucleoside that plays a crucial role in RNA oligonucleotide synthesis, where it selectively shields the 5'-hydroxyl group of RNA. Beyond this, it has emerged as a promising therapeutic contender in anti-cancer drug delivery and the treatment of viral infections. Grade: ≥95%. CAS No. 2305415-94-3. Molecular formula: C22H42N2O7Si2. Mole weight: 502.75.
2',3'-Bis-O-(t-butyldimethylsilyl)-N1-methylpseudoUridine - a modified nucleoside - is an indispensable constituent for RNA synthesis. Once aligned with RNA strands, RNA polymerases recognize it effortlessly, presenting an excellent model for analyzing RNA secondary structures and protein-RNA bonds. The nucleoside has proven useful, too, in sophisticated RNA medications that precisely target specific malignancies. Grade: ≥95% by HPLC. Molecular formula: C22H42N2O6Si2. Mole weight: 486.75.
2',3'-Bis-(O-t-butyldimethylsilyl)uridine
2',3'-Bis-(O-t-butyldimethylsilyl)uridine, a widely utilized compound in the realm of biomedicine, assumes an indispensable function in the amalgamation of nucleoside analogs and antiviral pharmaceuticals, notably AZT and acyclovir. Moreover, it exerts an inhibitory effect on viral replication, rendering it instrumental in combating illnesses such as HIV and herpes. Its exceptional attributes render this biomedical research and drug development tool truly invaluable. Synonyms: Uridine, 2',3'-bis-O-[(1,1-dimethylethyl)dimethylsilyl]-; 2',3'-Bis-O-tert-butyldimethylsilyluridine; 2'-O,3'-O-Bis(tert-butyldimethylsilyl)uridine; 2',3'-Bis-O-[dimethyl(2-methyl-2-propanyl)silyl]uridine; 2',3'-Bis-O-[(1,1-dimethylethyl)dimethylsilyl]uridine. Grade: ≥95%. CAS No. 69504-12-7. Molecular formula: C21H40N2O6Si2. Mole weight: 472.72.
An impurity of Febuxostat. Febuxostat is an antihyperuricemic nonpurine inhibitor of both the oxidized and reduced forms of xanthine oxidase. Synonyms: 3-Descyano 3-Bromo-febuxostat; Bromo febuxostat impurity; Febuxostat Impurity D. CAS No. 144060-40-2. Molecular formula: C15H16BrNO3S. Mole weight: 370.26.
2,3-Butanedione-2-monoxime
2,3-Butanedione-2-monoxime (BDM) is a non-selective, reversible myosin ATPase inhibitor with phosphatase-like properties. It is non-selective myosin ATPase inhibitor (Ki = 5 mM at myosin II). Uses: Cholinesterase reactivators. Synonyms: BDM; Diacetyl Monoxime; NSC 660; NSC 116103; Biacetyl monooxime. Grade: ≥95%. CAS No. 57-71-6. Molecular formula: C4H7NO2. Mole weight: 101.1.
2',3'-cAMP sodium salt
2',3'-cAMP is a positional isomer of 3',5'-cAMP that is produced by organ systems such as rat and mouse kidney and mouse brain through RNA degradation. When injured, organisms could produce 2',3'-cAMP and release it into the extracellular compartment. Synonyms: Adenosine-2':3'-cyclic monophosphate, sodium salt; Adenosine 2',3'-cyclic phosphate (sodium); Adenosine, cyclic 2',3'-(hydrogen phosphate), sodium salt (1:1); Adenosine, cyclic 2',3'-(hydrogen phosphate), monosodium salt; Adenosine 2',3'-cyclic monophosphate sodium salt; Adenosine 2',3'-cyclic phosphate sodium salt; Adenosine cyclic 2',3'-monophosphate sodium salt; NSC 154034. Grade: ≥97% by HPLC. CAS No. 37063-35-7. Molecular formula: C10H11N5NaO6P. Mole weight: 351.19.
2',3'-cGAMP
2',3'-cGAMP was considered to be the metazoan second messenger which is produced by cGAMP synthase (cGAS), the mammalian intrinsic immune DNA sensor. It can activate innate immunity by directly binding the endoplasmic reticulum-resident receptor STING (stimulator of interferon genes). Synonyms: Cyclic [G(2',5')pA(3',5')p]; 2'-Guanylic acid, adenylyl-(3'→5')-, cyclic nucleotide; 2',3'-Cyclic guanosine adenosine monophosphate; 2',3'-Cyclic guanosine monophosphate-adenosine monophosphate; 2'-3'-cyclic GMP-AMP; cGAMP(2'→5'); c[G(2',5')pA(3',5')p]; Cyclic Gp(2'→5')Ap(3'→5'). Grade: ≥95%. CAS No. 1441190-66-4. Molecular formula: C20H24N10O13P2. Mole weight: 674.41.
2'3'-cGAM(PS)2 (Rp/Sp)
A STING ligand. Synonyms: Di-thiophosphate analog of 2'3'cGAMP; c-(RpSp)-ApsGps; 2'3'-cGsAsMP. CAS No. 1637675-05-8. Molecular formula: C20H22N10O11P2S2 2Na. Mole weight: 750.5.
2',3'-cGAMP sodium salt
2',3'-cGAMP sodium is an endogenous cGAMP in mammalian cells. 2',3'-cGAMP sodium binds to STING with a high affinity and is a potent inducer of interferon-β. 2',3'-cGAMP is an effective adjuvant that boosts the production of antigen-specific antibodies and T cell responses in mice. Synonyms: Cyclic [G(2',5')pA(3',5')p] sodium; cyclic GMP-AMP sodium; 2',3'-cyclic GMP-AMP sodium; 2',3'-Cyclic guanosine monophosphate-adenosine monophosphate sodium salt. Grade: 95%. CAS No. 2734858-36-5. Molecular formula: C20H22N10Na2O13P2. Mole weight: 718.38.
2',3'-cGMP
2',3'-cGMP, a cyclic nucleotide with profound significance in the biomedical sector, takes center stage within this product description. Employed primarily as a research instrument, it facilitates an in-depth exploration of intracellular signaling cascades across diverse biological spectrums. Furthermore, 2',3'-cGMP assumes an indispensable role in overseeing cellular proliferation and differentiation. This versatile product harbors immense potential, warranting its employment in the realm of drug discovery. Synonyms: Guanosine- 2', 3'- cyclic monophosphate, sodium salt. Grade: ≥ 97 % by HPLC. CAS No. 15718-49-7. Molecular formula: C10H11N5O7P · Na. Mole weight: 367.2.
2',3'-cUMP
2',3'-cUMP, a nucleotide analog employed in biomedical research, exhibits promise in the treatment of diverse ailments such as cancer and viral infections. By serving as either a substrate or an inhibitor of specific enzymes implicated in DNA replication and RNA synthesis, it induces modifications within cellular mechanisms. Synonyms: Uridine- 2', 3'- cyclic monophosphate, sodium salt. Grade: ≥ 97% by HPLC. CAS No. 15718-50-0. Molecular formula: C9H10N2O8P · Na. Mole weight: 328.2.
2-(3-cyano-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylic acid 1-oxide is an impurity of Febuxostat. Febuxostat is an antihyperuricemic nonpurine inhibitor of both the oxidized and reduced forms of xanthine oxidase. CAS No. 2418591-42-9. Molecular formula: C16H16N2O4S. Mole weight: 332.37.
An impurity of Febuxostat. Febuxostat is an antihyperuricemic nonpurine inhibitor of both the oxidized and reduced forms of xanthine oxidase. Synonyms: Febuxostat Impurity 66. Grade: 99%. CAS No. 1380049-45-5. Molecular formula: C18H21N3O2S. Mole weight: 343.44.
An impurity of Febuxostat. Febuxostat is an antihyperuricemic nonpurine inhibitor of both the oxidized and reduced forms of xanthine oxidase. Synonyms: O-Desisobutyl-O-n-propyl Febuxostat; Febuxostat N-Propyl Ether Acid Impurity; Febuxostat Impurity U. CAS No. 1530308-87-2. Molecular formula: C15H14N2O3S. Mole weight: 302.35.
Kevetrin-[13C2,15N3] hydrochloride is the labelled analogue of Kevetrin hydrochloride. Kevetrin hydrochloride is a water-soluble small molecule with potential antineoplastic activity. It can inhibit cancer cell growth and cause tumor cell apoptosis. Synonyms: 2-(3-Cyanopropyl)isothiourea hcl (isothiourea-13C,15N2, nitrile-13C,15N); 2-(3-Cyanopropyl)isothiourea-13C2,15N3 hydrochloride; 4-Isothioureidobutyronitrile-13C2,15N3 Hydrochloride; Kevetrin-13C2,15N3 Hydrochloride; 3-Cyanopropyl Carbamimidothioate-13C2,15N3 Hydrochloride; 3-Cyanopropyl-carbamimidothioic Acid Ester-13C2,15N3 Hydrochloride; Kevetrin-(4-isothioureido-13C,15N2-butyronitrile-13C,15N) hydrochloride. Grade: ≥95% (CP); ≥98% atom 15N; ≥98% atom 13C. Molecular formula: C3[13C]2H9[15N]3S.HCl. Mole weight: 184.63.
2,3-DCPE hydrochloride
2,3-DCPE hydrochloride is a compound that selectively induces apoptosis and downregulates Bcl-XL protein expression in multiple human cancer cells versus normal cells in vitro. It also specifically cleaves caspase-8, caspase-3, caspase-9, and poly(ADP-ribose) polymerase in cancer cells. Uses: Antitumor agent. Synonyms: 2,3-DCPE HCl; 2-((3-(2,3-Dichlorophenoxy)propyl)amino)ethan-1-ol hydrochloride. Grade: ≥99% by HPLC. CAS No. 1009555-55-8. Molecular formula: C11H16Cl3NO2. Mole weight: 300.61.
2',3'-ddA-CE Phosphoramidite
The 2',3'-ddA-CE Phosphoramidite, an indispensable biomedical compound, finds widespread application in the synthesis of oligonucleotides for research investigations. It assumes a profound function in the advancement of targeted therapeutic drugs with a focus on distinct ailments and genetic anomalies, encompassing viral infections and specific cancer subtypes. Synonyms: N6-diisobutylaminomethylidene-2',3'-dideoxyAdenosine, 5'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite. Molecular formula: C28H47N8O3P. Mole weight: 574.70.
2',3'-ddA(N-Bz) CE Phosphoramidite
2',3'-ddA(N-Bz) CE Phosphoramidite is a modified phosphoramidite reagent designed for solid-phase oligonucleotide synthesis, enabling site-specific incorporation of 2',3'-dideoxyadenosine (ddA) with an N-benzoyl protecting group. This reagent lacks 2'- and 3'-hydroxyl groups, terminating chain elongation and making it ideal for synthesizing oligonucleotides with defined lengths, such as primers or sequencing tools. Synonyms: 2',3'-ddA(N-Bz) Phosphoramidite; 2',3'-Dideoxyadenosine (N-bz) 5'-phosphoramidite; N6-Benzoyl-2',3'-dideoxyadenosine, 5'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; 2',3'-ddA(Bz) CE Phosphoramidite; ((2S,5R)-5-(6-Benzamido-9H-purin-9-yl)tetrahydrofuran-2-yl)methyl (2-cyanoethyl) diisopropylphosphoramidite. Grade: ≥97%. Molecular formula: C26H34N7O4P. Mole weight: 539.58.
2',3'-ddC-CE Phosphoramidite
2',3'-ddC-CE Phosphoramidite, an essential chemical compound used in the synthesis of oligonucleotides for therapeutic application, possesses a remarkable capability to tackle viral infections and specific types of malignant tumors. By virtue of its singular configuration, this specialized chemical compound exerts curative impact exclusively on the designated cells while remaining benign to the healthy cells, which cogently endorses its potential as an invaluable weapon in the crusade against diseases. Synonyms: N4-diisobutylaminomethylidene-2',3'-dideoxyCytidine, 5'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite. Molecular formula: C27H47N6O4P. Mole weight: 550.68.
2',3'-ddC-CPG
2',3'-ddC-CPG is a biomedical product used in the research of viral infections, specifically targeting diseases caused by RNA viruses. It combines 2',3'-ddC, a potent antiviral drug, with CPG (Cytidine Phosphoramidite), a key component in synthetic DNA and RNA constructs. Synonyms: 5'-Dimethoxytrityl-N-succinoyl-long chain alkylamino-CPG, 2',3'-deoxyCytosine.
2',3'-ddC frits column (100nmol)
The 2',3'-ddC frits column (100nmol) - a superior and reliable column that serves as a high-performance liquid chromatography (HPLC) tool. Its function is to accurately separate nucleoside analog drugs, enabling the biomedicine industry to detect and quantify 2',3'-dideoxycytidine (ddC) and its metabolites, vital in the treatment of HIV/AIDS. Whether for drug discovery or quality control purposes, this frits column from nucleic acid isolation stands firm as an essential and highly advantageous component. Synonyms: 2',3'-ddC frits column.
2',3'-ddC frits column (200nmol)
2',3'-ddC frits column (200nmol) finds its purpose in the specialized analysis of nucleosides and their analogs. It is an essential tool for researchers who aim to delve deeper into the efficacy of these compounds against viruses like HIV. With its unique frits design, this column promises precision and accuracy in separating the compounds. Its ability to produce reliable results makes it a must-have in laboratories engaged in the investigation of these types of compounds. Synonyms: 2',3'-ddC frits column.
2',3'-ddC(N-Ac) CE Phosphoramidite
2',3'-ddC(N-Ac) CE Phosphoramidite is a modified phosphoramidite reagent designed for solid-phase oligonucleotide synthesis, enabling site-specific incorporation of 2',3'-dideoxycytidine (ddC) with an N-acetyl protecting group. This reagent lacks 2'- and 3'-hydroxyl groups, terminating chain elongation and making it ideal for synthesizing oligonucleotides with defined lengths, such as primers or sequencing tools. Synonyms: 2',3'-ddC(N-Ac) Phosphoramidite; 2',3'-Dideoxycytosine (N-Ac) 5'-phosphoramidite; N-Acetyl-2',3'-dideoxycytosine, 5'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; 2',3'-ddC(Ac) CE Phosphoramidite. Grade: ≥97%. Molecular formula: C20H32N5O5P. Mole weight: 453.48.
2',3'-ddG-CE Phosphoramidite
2',3'-ddG-CE Phosphoramidite is a key product used in the synthesis of modified nucleic acids for biomedical research. Specifically, it is used to introduce 2',3'-dideoxyguanosine (ddG) modifications into DNA or RNA strands. These modified nucleotides are useful in studying nucleic acid structure and function, as well as in developing new therapeutic approaches for diseases such as cancer and viral infections. Synonyms: N2-dimethylaminomethylidene-2',3'-dideoxyGuanosine, 5'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite. Molecular formula: C22H35N8O4P. Mole weight: 506.54.
2',3'-ddG(N-dmf) CE Phosphoramidite
2',3'-ddG(N-dmf) CE Phosphoramidite is a modified phosphoramidite reagent designed for solid-phase oligonucleotide synthesis, enabling site-specific incorporation of 2',3'-dideoxyguanosine (ddG) with an N-dimethylformamidine (N-dmf) protecting group. This reagent lacks 2'- and 3'-hydroxyl groups, terminating chain elongation and making it ideal for synthesizing oligonucleotides with defined lengths, such as primers or sequencing tools. Synonyms: 2',3'-ddG(N-dmf) Phosphoramidite; 2-Cyanoethyl (((2S,5R)-5-(2-(((dimethylamino)methylene)amino)-6-oxo-1,6-dihydro-9H-purin-9-yl)tetrahydrofuran-2-yl)methyl) diisopropylphosphoramidite; N2-Dimethylaminomethylidene-2',3'-dideoxyguanosine, 5'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; 2',3'-Dideoxyguanosine (N-DMF) 5'-phosphoramidite; 2',3'-ddG(DMF) CE Phosphoramidite. Grade: ≥97%. Molecular formula: C22H35N8O4P. Mole weight: 506.55.
2',3'-ddG(N-iBu) CE Phosphoramidite
2',3'-ddG(N-iBu) CE Phosphoramidite is a modified phosphoramidite reagent designed for solid-phase oligonucleotide synthesis, enabling site-specific incorporation of 2',3'-dideoxyguanosine (ddG) with an N-isobutyryl protecting group. This reagent lacks 2'- and 3'-hydroxyl groups, terminating chain elongation and making it ideal for synthesizing oligonucleotides with defined lengths, such as primers or sequencing tools. Synonyms: 2',3'-ddG(N-iBu) Phosphoramidite; N2-Isobutyryl-2',3'-dideoxyguanosine, 5'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; 2',3'-Dideoxyguanosine (N-iBu) 5'-phosphoramidite; 2',3'-ddG(iBu) CE Phosphoramidite; 2-Cyanoethyl (((2S,5R)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)tetrahydrofuran-2-yl)methyl) diisopropylphosphoramidite. Grade: ≥97%. Molecular formula: C23H36N7O5P. Mole weight: 521.56.