BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
×
Product
Description
Suppliers Website
Cerexin B1
It is produced by the strain of Bacillus cereus. It has anti-gram-positive bacterial activity. CAS No. 70943-81-6. Molecular formula: C66H99N15O18. Mole weight: 1390.58.
Cerexin B4
It is produced by the strain of Bacillus cereus. It has anti-gram-positive bacterial activity. CAS No. 70943-84-9. Molecular formula: C66H101N15O18. Mole weight: 1392.59.
Cerexin D4
It is produced by the strain of Bac.cereus Gp-3. It has anti-gram-positive bacterial activity. CAS No. 70943-88-3. Molecular formula: C66H101N15O17. Mole weight: 1376.60.
Cerulenin
It is produced by the strain of Cephctlosporium caerulene, Helicoceras oryzae, Acrooylindrium oryzae. It has weak antibacterial activity, but it has the effect of resisting yeast, ringworm epidermis, pear spore and mycoplasma. It can inhibit the biosynthesis of fatty acids and sterols, and also inhibit the biosynthesis of Polyketide. In recent years, it has been found to inhibit HIV. Uses: Antifungal agents. Synonyms: Cerulenin; Helicocerin; 2,3-Epoxy-4-oxo-7,10-dodecadienamide; 3-(1-Oxo-4,7-nonadienyl)oxiranecarboxamide. Grades: 98%. CAS No. 17397-89-6. Molecular formula: C12H17NO3. Mole weight: 223.27.
Cervicarcin
It is produced by the strain of Streptomyces ogaensis 1390. It had a strong inhibitory effect on sarcoma 180 and sarcoma NF, but had a weak effect on sarcoma 37, Ehrman's ascites cancer and Friend leukemia. Synonyms: NSC65380; NSC 65380; NSC-65380; 1,3,4,5,10-Pentahydroxy-2-methyl-3-[(3-methyloxiran-2-yl)carbonyl]-1,2,3,4-tetrahydro-4a,9a-epoxyanthracen-9(10H)-one; 4a,9a-Epoxy-3-(2,3-epoxybutyryl)-1,2,3,4,4a,9a-hexahydro-1,3,4,5,10-pentahydroxy-2-methyl-anthrone. CAS No. 18700-78-2. Molecular formula: C19H20O9. Mole weight: 392.36.
Cesium carbonate
Caesium carbonate or cesium carbonate is a white crystalline solid compound. Caesium carbonate has a high solubility in polar solvents such as water, alcohol and DMF. Its solubility is higher in organic solvents compared to other carbonates like potassium and sodium carbonates, although it remains quite insoluble in other organic solvents such as toluene, p-xylene, and chlorobenzene. This compound is used in organic synthesis as a base. It also appears to have applications in energy conversion. Uses: Cesium carbonate (cs2co3) is used in the beer-brewing industry to make the "head" of beer foamier. it is also used in glassmaking and to enhance the taste of mineral water. Synonyms: Dicesium carbonate. Grades: ≥ 99.5% (Assay). CAS No. 534-17-8. Molecular formula: Cs2CO3. Mole weight: 325.82.
Cetoniacytone A
It is produced by the strain of Actinomyces sp. Lu 9419. Cetoniacytone A has weak activity against gram-positive and negative bacteria. It can inhibit the growth of HEPG2 and MCF7 human tumor cell lines. GI50 is 3.2 ?ol/L. CAS No. 496775-48-5. Molecular formula: C9H11NO5. Mole weight: 213.19.
Cetoniacytone B
It is produced by the strain of Actinomyces sp. Lu 9419. It can inhibit the growth of HEPG2 and MCF7 human tumor cell lines. GI50 is 4.4 ?ol/L. Synonyms: C21249; (1r,5s,6r)-4-amino-5-hydroxy-1-(hydroxymethyl)-7-oxabicyclo[4.1.0]hept-3-en-2-one. Molecular formula: C7H9NO4. Mole weight: 171.15.
Cetrorelix Acetate
Cetrorelix Acetate is the acetate salt of cetrorelix, which is a potent and synthetic peptide antagonist of gonadotropin-releasing hormone (GnRH) receptor antagonist with IC50 value of 1.21 nM. It binds to radioligand murine LTK- cells with Kd value of 0.2 nM. It inhibits the activation of hGnRHR and a downstream luciferase reporter gene in murine LTK- cells by the GnRHR agonist [D-Trp6]GnRH. It suppresses production of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the pituitary gland. It prevents ovulation during in vitro fertilization. It causes prepubertal reduction in bone density, bone strength and bone modeling. It was used as a therapeutic agent for the treatment of blood cancers such as multiple myeloma (MM). It is also used to treat hormone-sensitive cancers of the breast and prostate. It also has antidepressant and anxiolytic activity in vivo. Uses: Fertility agents, female. Synonyms: D-Alaninamide, N-acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-L-tyrosyl-N5-(aminocarbonyl)-D-ornithyl-L-leucyl-L-arginyl-L-prolyl-, acetate (1:x); D-Alaninamide, N-acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-L-tyrosyl-N5-(aminocarbonyl)-D-ornithyl-L-leucyl-L-arginyl-L-prolyl-, acetate (salt); Cetrotid; Cetrotide; D 20761; NS 75A; Ovurelix; SB 075 acetate; Ac-D-2Nal-D-Phe(4-Cl)-D-3Pal-Ser-Tyr-D-Cit-Leu-Arg-Pro-D-Ala-NH2.CH3CO2H. Grades: >98%. CAS No. 145672-81-7. Molecular formula: C70H92ClN17O14.xC2H4O2. Mole weight: 1431.06 (free base).
CGP-9000
CGP-9000 is a semisynthetic cephalosporin which has a wide antibacterial spectrum. Its antibacterial activity was similar to that of cefalexin in vitro, but the effect of oral administration was 2-7 times stronger than that of cefalexin and cefradine in mice. Synonyms: CGP 9000; BRN 0587499. Molecular formula: C16H19N3O5S. Mole weight: 365.40.
CGRP (rat)
α-CGRP (rat) is an endogenous neuropeptide displaying vasodilator, cardiovascular, pro-inflammatory and metabolic effects. Synonyms: Calcitonin Gene-Related Peptide (rat). Grades: >95%. CAS No. 83651-90-5. Molecular formula: C162H262N50O52S2. Mole weight: 3806.3.
Chaetiacandin
It is produced by the strain of Monochaetia dimorphospora(Papulacadin). The activity of Chaetiacandin against Candida albicans was stronger than amphotericin B and 5-FC. Synonyms: LS-71333; D-Glucitol, 1,5-Anhydro-1-C-(2,4-Dihydroxy-6-(Hydroxymethyl)Phenyl)-4-O-(6-O-(1-Oxo-2,4-Decadienyl)-Beta-D-Galactopyranosyl)-, 3-(7-Hydroxy-2,4,8,10-Tetradecatetraenoate). CAS No. 96989-32-1. Molecular formula: C43H60O16. Mole weight: 832.92.
Chaetoatrosin
It is produced by the strain of Chaetomium atrobrunneum F449. Chaetoatrosin inhibits chitin synthase of IC50 of 104 ?/mL. Chaetoatrosin has antifungal activity including Pyricularia oryzae, Botrytis cinerea, Cryptococcus neoformans, Trichophyton mentagrophytea and so on. Synonyms: Chaetoatrosin A; chaetoatrosin-a; SCHEMBL12800163. Molecular formula: C14H14O5. Mole weight: 262.26.
Chaetocin
It is produced by the strain of Chaetomium minutum. It has the activity of anti-gram-positive bacteria and negative bacteria. Synonyms: Caetocin; Chetocin; 3,11a-Epidithio-11aH-pyrazino[1',2':1,5]pyrrolo[2,3-b]indole, bimol. deriv.; (+)-Chaetocin; (+)-Chaetocin A; Chaetocin A; [3S-[3α, 5aβ, 10bβ(3'R*, 5'aS*, 10'bS*, 11'aR*), 11aα]]-2, 2', 3, 3', 5a, 5'a, 6, 6'-Octahydro-3, 3'-bis(hydroxymethyl)-2, 2'-dimethyl-[10b, 10'b(11H, 11'H)-Bi-3, 11a-epidithio-11aH-pyrazino[1', 2':1, 5]pyrrolo[2, 3-b]indole]-1, 1', 4, 4'-tetrone; NSC-745363. Grades: >99% by HPLC. CAS No. 28097-03-2. Molecular formula: C30H28N6O6S4. Mole weight: 696.84.
Chaetoglobosin A
Chaetoglobosin A, a sort of a mycotoxic cytochalasan compound, could be obtained from endophytic fungus C. globosum and has been found to exhibit antibacterial and nematicidal activities. It is also found to be effective in inducing apoptosis of cancer cells. Synonyms: chaetoglobosins. Grades: ≥98%. CAS No. 50335-03-0. Molecular formula: C32H36N2O5. Mole weight: 528.64.
Chalcomycin
It is produced by the strain of Streptomyces bikiniensis. It is mainly against gram-positive bacteria and also has effect on mycobacterium. Synonyms: Miconomycin; CHALCOMYCIN; J-013176; (1S,2E,5S,7S,8R,9S,10E,14R,15R,16S)-5-hydroxy-15-[[(2R,3R,4R,5R,6R)-5-hydroxy-3,4-dimethoxy-6-methyl-tetrahydropyran-2-yl]oxymethyl]-8-[(2S,3R,4S,6R)-3-hydroxy-4-methoxy-6-methyl-tetrahydropyran-2-yl]oxy-5,7,9,14-tetramethyl-13,17-dioxabicyclo[14.1.0]heptadeca-2,10-diene-4,12-dione; Chalcomycin A; NSC 150439. CAS No. 20283-48-1. Molecular formula: C35H56O14. Mole weight: 700.81.
Chandrananimycin A
It is produced by the strain of Actinomadura sp. M048. Chandrananimycin A has anti-mucor activity, and anti-CCL HT29, MFXF 529L, MACL McF-7 et al tumor cell activity. Synonyms: Acetamide, N-(9-hydroxy-3-oxo-3H-phenoxazin-2-yl)-. CAS No. 664355-12-8. Molecular formula: C14H10N2O4. Mole weight: 270.24.
Chandrananimycin B
It is produced by the strain of Actinomadura sp. M048. Chandrananimycin B has anti-mucor activity, and anti-CCL HT29, MFXF 529L, MACL McF-7 et al tumor cell activity. Synonyms: Acetamide, 2-hydroxy-N-(3-oxo-3H-phenoxazin-2-yl)-; SCHEMBL3777988; 2-(2-hydroxyacetyl)amino-3h-phenoxazin-3-one. CAS No. 664355-13-9. Molecular formula: C14H10N2O4. Mole weight: 270.24.
Chandrananimycin C
It is produced by the strain of Actinomadura sp. M048. Chandrananimycin C has anti-mucor activity, and anti-CCL HT29, MFXF 529L, MACL McF-7 et al tumor cell activity. It is also have anti-gram-positive bacteria and algae activities. Molecular formula: C17H16N2O3. Mole weight: 296.32.
Chartreusin
It is produced by the strain of Streptomyces chartreusis. It has the activity of anti-gram-positive bacteria and mycobacterium. Chartreusin is an antitumour antibiotic that binds to GC-rich tracts in DNA, with a clear preference for B-DNA over Z-DNA; inhibits RNA synthesis and causes single-strand scission of DNA via the formation of free radicals; a potent inhibitor of topoisomerase II. Synonyms: Lambdamycin; Antibiotic X-465A; NSC 5159; (1R,2R,3aS,8aR)-1-[(Z)-5-hydroxy-3-(hydroxymethyl)pent-3-enyl]-1-(hydroxymethyl)-2,5-dimethyl-2,3,4,7,8,8a-hexahydroazulene-3a-carbaldehyde; 10-[[6-Deoxy-2-O-(6-deoxy-3-O-methyl-α-D-galactopyranosyl)-β-D-galactopyranosyl]oxy]-6-hydroxy-1-methylbenzo[h][1]benzopyrano[5,4,3-cde][1]benzopyran-5,12-dione. Grades: >99% by HPLC. CAS No. 6377-18-0. Molecular formula: C32H32O14. Mole weight: 640.59.
Cheimonophyllon A
It is produced by the strain of Cheimonophyllum candidissiumun sing. It has nematode killing, cytotoxicity (L1210, HL60, BHK21) and weak antifungal bacterial activity. Molecular formula: C15H22O4. Mole weight: 266.33.
Cheimonophyllon E
It is produced by the strain of Cheimonophyllum candidissiumun sing. It has nematode killing, cytotoxicity (L1210, HL60, BHK21) and weak antifungal bacterial activity. CAS No. 160299-94-5. Molecular formula: C15H24O4. Mole weight: 268.30.
Chetomin
It is produced by the strain of Chaetomium cochloides , Ch.globosum, Ch.fuunienlum, Ch.elatun, Ch.spirale and Verticillium cinnabarium. Chetomin is a natural metabolite produced by several species of the genus chaetomium. It is an epidithiodioxopiperazine and is an inhibitor of hypoxia-inducible factor (HIF). It inhibits interaction of HIF1α and HIF2α with transcriptional co-activators p300 and cAMP response element binding (CREB) protein (CBP). It decreases tumor growth by attenuating hypoxia-inducible transcription and disrupting the ability of tumors to adapt to hypoxia. It also suppresses the proliferation of LPS-induced mouse spleen lymphocytes. It may be used as an antibacterial agent and is used in antitumor research. It also may be useful in radiotherapeutic. Synonyms: CTM; NSC-289491; NSC 289491; NSC289491; Chaetomin; (3S,5aR,10bS,11aS)-2,3,5a,6,10b,11-Hexahydro-3-(hydroxymethyl)-10b-[(1S,4S)-3-[[4-(hydroxymethyl)-5,7-dimethyl-6,8-dioxo-2,3-dithia-5,7-diazabicyclo[2.2.2]oct-1-yl]methyl]-1H-indol-1-yl]-2-methyl-3,11a-epidithio-11aH-pyrazino[1',2':1,5]pyrrolo[2,3-b]indole-1,4-dione. Grades: ≥98% by HPLC. CAS No. 1403-36-7. Molecular formula: C31H30N6O6S4. Mole weight: 710.87.
Chevalone C
Chevalone C is a meroterpenoid fungal metabolite originally isolated from E. chevalieri. It is active against M. tuberculosis H37Ra (MIC = 6.3 μg/ml) and is cytotoxic to BC1 human breast cancer cells (IC50 = 8.7 μg/ml). Chevalone C inhibits the growth of multidrug-resistant isolates of E. coli, S. aureus and E. faecium in a disc diffusion assay when used at a concentration of 15 μg/disc. It also induces cell death in HCT116 colorectal carcinoma cells. Synonyms: NCGC00380981-01; (2S, 4aR, 4bR, 6aS, 12aS, 12bR, 14aR)-2-(acetyloxy)-2, 3, 4, 4a, 4b, 5, 6, 6a, 12, 12a, 12b, 13, 14, 14a-tetradecahydro-1, 1, 4a, 6a, 9, 12b-hexamethyl-1H, 11H-phenanthro[2, 1-b]pyrano[3, 2-e]pyran-11-one. Grades: ≥95%. CAS No. 1318025-77-2. Molecular formula: C28H40O5. Mole weight: 456.61.
Chicamycin A
Chicamycin A is produced by the strain of Streptomyces albus J576-99. It has anti-tumor activity and weak anti-gram-positive bacteria activity. Synonyms: 5H-Pyrrolo(2,1-c)(1,4)benzodiazepin-5-one, 1,2,3,10,11,11a-hexahydro-2,8-dihydroxy-7,11-dimethoxy-, (2S-(2-alpha,11-alpha,11b-beta))-; BRN 5763463. CAS No. 89675-37-6. Molecular formula: C14H18N2O5. Mole weight: 294.30.
Chicamycin B
Chicamycin B is produced by the strain of Streptomyces albus J576-99. It has anti-tumor activity and weak anti-gram-positive bacteria activity. Synonyms: 5H-Pyrrolo(2,1-c)(1,4)benzodiazepin-5-one, 1,2,3,11a-tetrahydro-2,8-dihydroxy-7-methoxy-, (2S-trans)-. CAS No. 89675-39-8. Molecular formula: C13H14N2O4. Mole weight: 262.26.
Chimeramycin A
Chimeramycin A is produced by the strain of Streptomyces ambofaciens. It has anti-gram-positive bacterial and mycoplasma activities. Grades: >98%. CAS No. 87084-47-7. Molecular formula: C48H82N2O14. Mole weight: 911.17.
Chimeramycin B
Chimeramycin B is produced by the strain of Streptomyces ambofaciens. It has anti-gram-positive bacterial and mycoplasma activities. Molecular formula: C46H80N2O13. Mole weight: 869.13.
Chivosazol A
It is produced by the strain of Sorangium cellulosum So ce12. Chivosazol A has anti-yeast and filamentous fungal activity and has strong toxicity to mammalian cells. Molecular formula: C49H71NO12. Mole weight: 866.08.
Chloramphenicol acetate
It is a naturally-occurring co-metabolite of chloramphenicol in streptomyces venezuelae with albeit significantly lower potency. It is the major product of chloramphenicol acetyltransferase. Synonyms: 3-O-Acetylchloramphenicol; Chloramphenicol 3-acetate; 3-Acetylchloramphenicol; Acetamide, N-(1-((acetyloxy)methyl)-2-hydroxy-2-(4-nitrophenyl)ethyl)-2,2-dichloro-, (R-(R*,R*))-; D-threo-(-)-2,2-Dichloro-N-[β-hydroxy-α-(hydroxymethyl)-p-nitrophenethyl]acetamide α-Acetate. Grades: >99% by HPLC. CAS No. 10318-16-8. Molecular formula: C13H14Cl2N2O6. Mole weight: 365.17.
Chloramphenicol palmitate
Chloramphenicol palmitate is an antibacterial and antirickettsial. Synonyms: Chloramphenicol 3-palmitate. Grades: >99% by HPLC. CAS No. 530-43-8. Molecular formula: C27H42Cl2O6. Mole weight: 533.52.
Chloramphenicol succinate
Prepared by acylation of chloramphenicol with succinic anhydride to provide a water soluble pro-drug; represents an alternative prodrug strategy for chloramphenicol that has found a niche in surface antibiotic treatment in surgery; acts as a prodrug, forming chloramphenicol in the presence of succinate dehydrogenase. Synonyms: Kemicetine. Grades: >99% by HPLC. CAS No. 3544-94-3. Molecular formula: C15H16Cl2N2O8. Mole weight: 423.20.
Chloramphenicol succinate sodium
Chloramphenicol succinate sodium salt is a semi-synthetic broad-spectrum antibiotic. Synonyms: Chloramphenicol sodium succinate; Protophenicol. Grades: ≥80% by HPLC. CAS No. 982-57-0. Molecular formula: C15H15Cl2N2O8Na. Mole weight: 445.18.
Chlorflavonin
It is produced by the strain of Aspergillus candidus. Chlorflavonin has the activities of anti-aspergillus, yeast, botrytis, and other fungal. Among these fungi, anti-aspergillus fumigata activity is particularly strong, the minimum inhibitory concentration up to 0.08 μg/mL. Synonyms: 3'-Chloro-2',5-dihydroxy-3,7,8-trimethoxyflavone; Flavone, 3'-chloro-2',5-dihydroxy-3,7,8-trimethoxy-. CAS No. 23363-64-6. Molecular formula: C18H15ClO7. Mole weight: 378.76.
Synonyms: ClAc-L-Nle-OH; Chloroacetyl-L-2-aminohexanoic acid; ClAc L Nle OH. Grades: ≥ 99%. CAS No. 56787-36-1. Molecular formula: C8H14NO3Cl. Mole weight: 207.65.
Chloroacetyl-L-serine
Cas No. 80174-65-8. Molecular formula: C5H8NO4Cl. Mole weight: 181.53.
Chlorobiocin
Chlorobiocin is produced by the strain of Streptomyces hygroscopicus DS 9751 and Novobiocin. Chlorobiocin is found to bind at a second ATP-binding site in the C-terminal domain of Hsp90, thus disrupting the dimerization of the Hsp90 complex. IC50=60 μmol/L. Synonyms: Clorobiocin; Antibiotic RP 18,631; NSC 227186. Grades: >98%. CAS No. 39868-96-7. Molecular formula: C35H37ClN2O11. Mole weight: 697.13.
Chlorogentisylquinone is produced by the strain of FOM-8108. The IC50 of inhibitory rat meningeal nSMase was 1.2μmol/L, and the IC50 of P388 cells was 7.6μmol/L. Synonyms: 2,5-Cyclohexadiene-1,4-dione, 2-chloro-6-(hydroxymethyl)-. CAS No. 333344-08-4. Molecular formula: C7H5ClO3. Mole weight: 172.57.
Chloromonicin
Chloromonicin is produced by the strain of Monilinia fructicola. Its effect is mainly against candida albicans and hair fester bacteria. Molecular formula: C16H11O7Cl. Mole weight: 350.71.
Chloronectrin
Chloronectrin is produced by the strain of Nectria coccinea. It has anti-gram-positive bacterial activity. Synonyms: Chloronectrin. CAS No. 38965-84-3. Molecular formula: C25H33ClO6. Mole weight: 464.98.
Chloro-N, N, N', N'-tetra methyl formamidiniumHexafluorophosphate
Coupling reagent for peptide synthesis and starting material for preparing other coupling reagents. Synonyms: TCFH; N,N,N',N'-Tetramethylchloroformamidinium-hexafluorophosphate; N-(Chloro(dimethylamino)methylene)-N-methylmethanaminium hexafluorophosphate; TCFH, Chloro-N,N,N',N'-tetramethylformamidinium hexafluorophosphate; Methanaminium, N-[chloro(dimethylamino)methylene]-N-methyl-, hexafluorophosphate(1-) (1:1); Tetramethylchloroformamidinium Hexafluorophosphate. Grades: 99% (HPLC). CAS No. 94790-35-9. Molecular formula: C5H12ClF6N2P. Mole weight: 280.58.
Chloroorienticin A
Chloroorienticin A is produced by the strain of Amycolatopsis orientalis (Nocardia orientalis) PA-45052. Each component of Chloroorienticin had anti-Staphylococcus aureus and methicillin-resistant Staphylococcus aureus (MRSA) activity, and the activity was stronger than that of orientalis and vancomycin. Synonyms: Chloroeremomycin. CAS No. 118395-73-6. Molecular formula: C73H88Cl2N10O26. Mole weight: 1592.43.
Chloroorienticin B
Chloroorienticin B is produced by the strain of Amycolatopsis orientalis (Nocardia orientalis) PA-45052. Each component of Chloroorienticin had anti-Staphylococcus aureus and methicillin-resistant Staphylococcus aureus (MRSA) activity, and the activity was stronger than that of orientalis and vancomycin. Synonyms: Dihydrobalhimycin. CAS No. 118373-81-2. Molecular formula: C66H75Cl2N9O24. Mole weight: 1449.25.
Chloroorienticin C
Chloroorienticin C is produced by the strain of Amycolatopsis orientalis (Nocardia orientalis) PA-45052. Each component of Chloroorienticin had anti-Staphylococcus aureus and methicillin-resistant Staphylococcus aureus (MRSA) activity, and the activity was stronger than that of orientalis and vancomycin. Synonyms: Vancomycin, 22-O-(3-amino-2,3,6-trideoxy-3-C-methyl-alpha-L-arabino-hexopyranosyl)-14-O-de(2-O-(3-amino-2,3,6-trideoxy-3-C-methyl-alpha-L-arabino-hexopyranosyl)-beta-D-glucopyranosyl)-. CAS No. 118373-82-3. Molecular formula: C60H65Cl2N9O19. Mole weight: 1287.11.
Chloroorienticin D
Chloroorienticin D is produced by the strain of Amycolatopsis orientalis (Nocardia orientalis) PA-45052. Each component of Chloroorienticin had anti-Staphylococcus aureus and methicillin-resistant Staphylococcus aureus (MRSA) activity, and the activity was stronger than that of orientalis and vancomycin. Synonyms: Vancomycin, 22-O-(3-amino-2,3,6-trideoxy-3-C-methyl-alpha-L-arabino-hexopyranosyl)-56-methyl-. CAS No. 118373-83-4. Molecular formula: C74H90Cl2N10O26. Mole weight: 1606.46.
Chloroorienticin E
Chloroorienticin E is produced by the strain of Amycolatopsis orientalis (Nocardia orientalis) PA-45052. Each component of Chloroorienticin had anti-Staphylococcus aureus and methicillin-resistant Staphylococcus aureus (MRSA) activity, and the activity was stronger than that of orientalis and vancomycin. Synonyms: Vancomycin, 22-O-(3-amino-2,3,6-trideoxy-3-C-methyl-alpha-L-arabino-hexopyranosyl)-2'-O-de(3-amino-2,3,6-trideoxy-3-C-methyl-alpha-L-arabino-hexopyranosyl)-56-methyl-. CAS No. 118373-84-5. Molecular formula: C67H77Cl2N9O24. Mole weight: 1463.28.
Chloropolysporin B
Chloropolysporin B is produced by the strain of Faenia interjecta SANK 60983. It has strong activity of anti-gram-positive bacteria, including clinically isolated methicillin-resistant Staphylococcus aureus (MRSA) and enterococcus bacteria. Chloropolysporin B and other glycopeptide antibiotics can also promote the growth of broiler chickens. Synonyms: 10,49-Dichloro-2D-O-de(3-amino-2,3,6-trideoxy-alpha-L-ribo-hexopyranosyl)avoparcin alpha. CAS No. 105650-11-1. Molecular formula: C83H89Cl3N8O34. Mole weight: 1848.98.
Chloropolysporin C
Chloropolysporin C is produced by the strain of Faenia interjecta SANK 60983. It has strong activity of anti-gram-positive bacteria, including clinically isolated methicillin-resistant Staphylococcus aureus (MRSA) and enterococcus bacteria. C has a strong synergistic effect with β-lactam antibiotics. Synonyms: Derhamnosylchloropolysporin B; Avoparcin alpha, 10,49-dichloro-2(sup D)-O-de(3-amino-2,3,6-trideoxy-alpha-L-ribo-hexopyranosyl)-59-O-de(6-deoxy-alpha-L-mannopyranosyl)-. CAS No. 105650-12-2. Molecular formula: C77H79Cl3N8O30. Mole weight: 1702.84.
Chloroquinocin
Chloroquinocin is produced by the strain of Streptomyces sp. LL-A9227. It has moderate activity against gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA). Molecular formula: C17H15ClO5. Mole weight: 334.75.
Chlororaphin
It is produced by the strain of Pseudomonas chlororaphis. It is an antibiotic with activity against gram-positive bacteria. Synonyms: 1-Carbamoyl-10H-phenazin-5-yl radical; 1-(Aminocarbonyl)-5(10H)-phenazinyl. CAS No. 13397-28-9. Molecular formula: C13H11N3O. Mole weight: 225.25.
Chlorothricin
Chlorothricin is produced by the strain of Streptomyces antibioticus Tu 99. Related to kijanimicin, saccharocarcins, tetrocarcins and versipelostatin. It inhibits cholesterol biosynthesis from mevalonate, and inhibits pyruvate carboxylases purified from rat liver, chicken liver and azotobacter vinelandii. Synonyms: (4S, 4aS, 6aR, 11E, 12aR, 15R, 16aS, 21aR, 21bR)-4-[[4-O-[3-O-(3-Chloro-6-methoxy-2-methylbenzoyl)-2, 6-dideoxy-β-D-arabino-hexopyranosyl]-2, 6-dideoxy-β-D-arabino-hexopyranosyl]oxy]-1, 2, 3, 4, 4a, 6a, 7, 8, 9, 10, 12a, 15, 16, 21, 21a, 21b-hexadecahydro-22-hydroxy-15, 21a-dimethyl-18, 21-dioxo-18H-16a, 19-metheno-16aH-benzo[e]naphtho[2, 1-m][1, 4]dioxacyclopentadecin-14-carboxylic Acid; [4S-(4R*, 4aR*, 6aS*, 11E, 12aS*, 15S*, 16aR*, 21aS*, 21bS*)]-4-[[4-O-[3-O-(3-Chloro-6-methoxy-2-methylbenzoyl)-2, 6-dideoxy-β-D-arabino-hexopyranosyl]-2, 6-dideoxy-β-D-arabino-hexopyranosyl]oxy]-1, 2, 3, 4, 4a, 6a, 7, 8, 9, 10, 12a, 15, 16, 21, 21a, 21b-hexadecahydro-22-hydroxy-15, 21a-dimethyl-18, 21-dioxo-18H-16a, 19-metheno-16aH-benzo[e]naphtho[2, 1-m][1, 4]dioxacyclopentadecin-14-carboxylic Acid. Grades: >99% by HPLC. CAS No. 34707-92-1. Molecular formula: C50H63ClO16. Mole weight: 955.48.
Crystalline reagent for peptide coupling of a-alkylated N-Fmoc and N-Z-amino acids in high yield and without racemization. Synonyms: PyClOP; chloro-tripyrrolidino-phosphonium hexa-fluorophosphate; PyClOPChlorotri pyrrolidinophosphonium hexafluorophosphate; chloro-tris(1-pyrrolidinyl)phosphonium hexafluorophosphate; (T-4)chlorotri-1-pyrrolidinylphosphorus(1+) Hexafluorophosphate(1-); Pyrrolidine, Phosphorus Complex; PyCloP; Tris(1-pyrrolidino)chloroimidazolium Hexafluorophosphate. Grades: ≥ 98% (HPLC). CAS No. 133894-48-1. Molecular formula: C12H24F6N3P2Cl. Mole weight: 421.74.
Chlovalicin
Chlovalicin is produced by the strain of Sporothrix sp. FO-4649. In the presence of 0.2 U/mL interleukin-6 (IL-6), clopentine inhibited the growth of L6-dependent MH60 cells with lC50 of 7.5 μmol/L. It also inhibited the growth of B16 melanoma cells with lC50 of 38μmol/L. Molecular formula: C16H25ClO5. Mole weight: 332.82.
Chondramide A
It is produced by the strain of Chondromyces crocatus. Chondramide A has anti-candida, Henson yeast, lipids yeast, ball-like yeast and other fungal activities, but has no anti-gram positive and negative bacteria activities. Synonyms: (3S)-3beta-Methoxy-4alpha-(4-hydroxyphenyl)-7beta-(1H-indole-3-ylmethyl)-8,10alpha,13beta,15,17beta,18beta-hexamethyl-1-oxa-5,8,11-triazacyclooctadeca-15-ene-2,6,9,12-tetraone; CHEBI:84380. Molecular formula: C36H46N4O7. Mole weight: 646.77.
Chondramide B
It is produced by the strain of Chondromyces crocatus. Chondramide B has anti-candida, Henson yeast, lipids yeast, ball-like yeast and other fungal activities, but has no anti-gram positive and negative bacteria activities. Synonyms: CHEBI:84381. Molecular formula: C36H45ClN4O7. Mole weight: 681.22.
Chondramide C
It is produced by the strain of Chondromyces crocatus. Chondramide C has anti-candida, Henson yeast, lipids yeast, ball-like yeast and other fungal activities, but has no anti-gram positive and negative bacteria activities. Synonyms: CHEBI:84382. Molecular formula: C35H44N4O6. Mole weight: 616.75.
Chondramide D
It is produced by the strain of Chondromyces crocatus. Chondramide D has anti-candida, Henson yeast, lipids yeast, ball-like yeast and other fungal activities, but has no anti-gram positive and negative bacteria activities. Synonyms: CHEBI:84383. Molecular formula: C35H43ClN4O6. Mole weight: 651.19.
Chrodrimanin B
Chrodrimanin B is a meroterpenoid fungal metabolite that has been found in Talaromyces species. It has insecticidal activity against third instar silkworm larvae (LD50 = 10 μg/g of diet) and selectively inhibits the silkworm GABA receptor RDL (IC50 = 1.13 nM) over human α1β2γ2 subunit-containing GABA receptors (IC50 = 1.48 μM). Synonyms: Thailandolide B; (1R,2R,7aR,8S,9aR,13aS,13bS)-1-(acetyloxy)-1,8,9,9a,10,13a,13b,14-octahydro-5,8-dihydroxy-2,7a,10,10,13a-pentamethyl-2H,4H-benzo[a]pyrano[3,4-j]xanthene-4,11(7aH)-dione; (-)-Chrodrimanin B. Grades: ≥95%. CAS No. 132196-54-4. Molecular formula: C27H32O8. Mole weight: 484.54.
Chrolactomycin
It is produced by the strain of Streptomyces sp. 569N-3. The IC50 of Chrolactomycin for ACHN, A431, McF-7 and T24 cells was (μmol/L) 1.2, 1.6, 0.69 and 0.45, respectively. Chrolactomycin has only anti-gram-positive bacteria activity with the MIC 5.2-10.4μg/mL. Molecular formula: C24H32O7. Mole weight: 432.51.
Chromomycin A2
Chromomycin A2 is produced by the strain of Streptomyces olivochromogenes 69895. A minor, more hydrophobic analogue of the chromomycin complex of the aureolic acid class; originally isolated from S. Aburaviensis and named aburamycin; exhibits a broad biological profile as an antibacterial, antifungal and antitumor agent. Synonyms: Aburamycin A; NSC 131187. Grades: >98% by HPLC. CAS No. 6992-70-7. Molecular formula: C59H86O26. Mole weight: 1211.30.
Chromomycin A3
Chromomycin A3 is produced by the strain of Streptomyces olivochromogenes 69895. The major component of the chromomycin complex of the aureolic acid class; isolated from several streptomyces species; exhibits a broad biological profile as an antibacterial, antifungal and antitumour agent; binds reversibly to GC-specific DNA ligand in the minor groove which inhibits transcription, DNA gyrase and topoisomerase II activity. Synonyms: Aburamycin; Toyomycin; NSC 58514; B 599-III; SR1768E. Grades: >98% by HPLC. CAS No. 7059-24-7. Molecular formula: C57H82O26. Mole weight: 1183.24.
Chrymutasin A
Chrymutasin A is produced by the strain of Streptomyces chartreusis D329. The IC50 of P388, Meth A, A549, MKN45 and WiDr cells were 0.76, 1.55, 4.25, 1.35 and 1.56 g/mL, respectively. Synonyms: SCHEMBL9034929; D-329P. CAS No. 155213-40-4. Molecular formula: C33H33NO13. Mole weight: 651.61.
Chrymutasin B
Chrymutasin B is produced by the strain of Streptomyces chartreusis D329. Chrymutasin B is cytotoxic. Molecular formula: C32H31NO13. Mole weight: 637.59.
Chrymutasin C
Chrymutasin C is produced by the strain of Streptomyces chartreusis D329. Chrymutasin C is cytotoxic. Synonyms: D-329R. CAS No. 155232-80-7. Molecular formula: C39H43NO17. Mole weight: 797.75.
Chrysomycin A
Chrysomycin A is a C-glycoside antitumor antibiotic isolated from Streptomyces, and it is an inhibitor of the catalytic activity of human topoisomerase II. It has effective antibacterial, antifungal, antiviral and antitumor activities. It may act as a light-activated cross-linking agent between DNA and histones. Synonyms: Chrysomycin V; Virenomycin V; Albacarcin V. Grades: >99% by HPLC. CAS No. 82196-88-1. Molecular formula: C28H28O9. Mole weight: 508.51.
Chrysomycin B
Chrysomycin B is a minor analogue in a complex of C-glycoside antitumor active substances isolated from Streptomyces. Its activity is lower than that of its vinyl analogue (Chrysomycin A), but it still has strong anti-tumor activity and is an inhibitor of the catalytic activity of human topoisomerase II. It can be used as a light-activated cross-linking agent for DNA and histones. Synonyms: Chrysomycin M; Virenomycin M; Albacarcin M. Grades: >98% by HPLC. CAS No. 83852-56-6. Molecular formula: C27H28O9. Mole weight: 496.50.
Chrysospermin A
It is produced by the strain of Apiocrea chrysosperma Ap101. Chrysospermin A has antibacterial activities against individual gram-positive bacteria (Staphylococcus aureus, Bacillus subtilis), Klebsiella pneumoniae and individual yeasts (Ocher echinoderma, saccharomyces cerevisiae). CAS No. 160824-57-7. Molecular formula: C90H140N22O23. Mole weight: 1898.20.