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5'-O-DMT-2'-O-methoxyethyl-5-methyluridine
5'-O-DMT-2'-O-methoxyethyl-5-methyluridine, a remarkable biomedicine, holds immense importance in the pursuit of antiviral therapies within the realm of scientific investigation. Radar-like in its efficacy, this compound displays a formidable ability to combat a diverse array of viral pathogens, with a specific proclivity for RNA viruses. Enabled by its distinctive molecular architecture, the potential of this extraordinary entity in addressing RNA virus-related ailments opens up captivating prospects for pioneering drug exploration and advancement, poised to revolutionize the intricate landscape of the biomedical sphere. Molecular formula: C34H38N2O9. Mole weight: 618.68.
5'-O-DMT-2'-O-methyl-5-methylcytidine 3'-CE phosphoramidite is a phosphoramidite derivative used in the research and development of modified RNA oligonucleotides. This compound contains a 3'-CE phosphoramidite group allowing for efficient and site-specific attachment to the growing chain during solid-phase research and development. It can be utilized in research involving RNA modification or RNA therapeutics development for the research of various diseases. CAS No. 1163684-29-4. Molecular formula: C41H52N5O8P. Mole weight: 773.85.
5'-O-DMT-2'-O-methyl-5-methyluridine
5'-O-DMT-2'-O-methyl-5-methyluridine is a modified nucleoside molecule that contains a 5'-O-dimethoxytrityl (DMT) group on the 5' carbon, a 2'-O-methyl group on the 2' carbon, and a methyl group on the 5th carbon of the uracil base. This modification is commonly used in nucleic acid synthesis and research to protect and manipulate nucleosides for various applications. Synonyms: 5'-DMT-5-Me-2'-OMe-U; DMT-5-Me-2'-OMe-U; Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-5-methyl-2'-O-methyl-; 5'-O-[bis(4-methoxyphenyl)?phenylmethyl]?-5-methyl-2'-O-methyl-Uridine; 5'-O-(Dimethoxytrityl)-2'-O-methyl-5-methyluridine; 5-Methyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methyl-uridine. Grade: ≥97% by HPLC. CAS No. 153631-19-7. Molecular formula: C32H34N2O8. Mole weight: 574.62.
5'-O-DMT-2'-O-methyl-5-methyluridine 3'-CE phosphoramidite is a novel antiviral and anticancer agent. Synonyms: 5'-O-DMT-5-Methy-2'-O-methyluridine 3'-CE phosphoramidite; 5'-O-DMT-2'-O-methyl-5-methyl-D-uridine 3'-CE phosphoramidite; 2'-O-Methyl-5-methyl-U CEP; 5-O-(4,4'-dimethoxytrityl)-3-O-(diisopropylamino-2-cyanoethoxyphosphanyl)-1-deoxy-2-O-methyl-1-thymin-1-yl-beta-D-ribo-pentofuranose; 5-Methyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methyl-uridine-3'-cyanoethyl phosphoramidite. Grade: ≥98% by HPLC. CAS No. 153631-20-0. Molecular formula: C41H51N4O9P. Mole weight: 774.86.
5'-O-DMT-2'-O-methylcytidine
5'-O-DMT-2'-O-methylcytidine is a biomedicine research product used for the treatment of viral infections, cancer, and neurological disorders. It acts as an antiviral and anticancer agent by inhibiting viral replication and tumor growth, respectively. Additionally, it also has neuroprotective properties that help in treating neurological disorders. Synonyms: 5'-O-(4,4'-dimethoxytrityl)-2'-O-methyl-cytidine; DMT-2'-OMe-Cr; 5'-O-DMT-2'-O-methyl-D-cytidine; 5'-O-DMT-2'-OMe-rC; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-O-methylcytidine. Grade: ≥98% by HPLC. CAS No. 103285-21-8. Molecular formula: C31H33N3O7. Mole weight: 559.62.
5'-O-DMT-2'-O-methylguanosine
5'-O-DMT-2'-O-methylguanosine, a nucleoside analogue, finds its purpose in biomedical research due to its potential antiviral activity against RNA viruses, an area of significant scientific interest. Its inhibitory role in the replication of notorious viruses such as Zika virus and hepatitis C virus warrants further academic study. Synonyms: 5'-O-(4,4'-dimethoxytrityl)-2'-O-methyl-guanosine; DMT-2'-OMe-Gr; 2'-O-Methyl-5'-O-DMT-D-guanosine; 5'-O-Dimethoxytrityl-2'-O-methylguanosine; 5'-O-DMT-2'-O-methyl-D-guanosine; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-O-methylguanosine. Grade: ≥98% by HPLC. CAS No. 103285-24-1. Molecular formula: C32H33N5O7. Mole weight: 599.65.
5'-O-DMT-2'-O-methylinosine 3'-CE phosphoramidite
5'-O-DMT-2'-O-methylinosine 3'-CE phosphoramidite is a vital component used in the research and development of RNA molecules for biomedical research. It functions as a phosphoramidite building block to introduce the modified nucleoside 5'-O-DMT-2'-O-methylinosine into RNA sequences. This modified nucleoside plays a crucial role in studying the structure, function and therapeutic potential of RNA molecules involved in various diseases, including cancer and genetic disorders. Synonyms: 2'-OMe-I-CE Phosphoramidite; 2'-O-Methyl Inosine Phosphoramidite; 5'-O-(4,4-Dimethoxytrityl)-2'-O-methyl inosine-3'-CED phosphoramidite; 5'-O-(4,4'-Dimethoxytrityl)-2'-O-methyl-inosine-3'-cyanoethyl phosphoramidite; Inosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-methyl-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]; 5'-Dimethoxytrityl-Inosine, 2'-O-methyl, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; 2'-O-Methyl Inosine CED phosphoramidite; 2'-O-Methyl-I CEP. Grade: ≥98%. CAS No. 128219-85-2. Molecular formula: C41H49N6O8P. Mole weight: 784.83.
5'-O-DMT-2'-O-methyl-N6-phenoxyacetyladenosine
5'-O-DMT-2'-O-methyl-N6-phenoxyacetyladenosine is an immensely powerful biomedical compound, used in the research of inflammatory disorders and autoimmune diseases. This exquisite molecule, through its adept nature, selectively engages receptors and signaling pathways, exuding anti-inflammatory prowess. Synonyms: 5'-DMT-2'-(O-Methyl) Adenosine (n-PAC); 5'-O-(4,4'-Dimethoxytrityl)-N6-Phenoxyacetyl-2'-O-methyl-Adenosine; 5'-O-DMT-N6-PAc-2'-OMe-rA; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-O-methyl-N-(2-phenoxyacetyl)adenosine; 5'-O-DMT-2'-O-methyl-N6-phenoxyacetyladenosine; 5'-O-DMT-2'-O-methyl-N6-phenoxyacetyl-D-adenosine; 5'-O-DMT-2'-OMe-N6-Pac-rA. Grade: ≥98% by HPLC. CAS No. 128219-81-8. Molecular formula: C40H39N5O8. Mole weight: 717.77.
5'-O-DMT-2'-O-methyl-N6-phenoxyacetyladenosine 3'-CE phosphoramidite is a promising molecular implement utilized in the synthesis of modified oligonucleotides that can be used in various applications including RNA interference and antisense therapy for treating multifarious diseases like viral infections, genetic disorders, and cancer. With the potential to revolutionize the field of medicine, this molecular tool boasts unparalleled effectiveness in terms of successfully delivering modified oligonucleotides to their targets with precision. Synonyms: 2'-OMe-Pac-A phosphoramidite; 5'-O-DMT-2'-O-methyl-N6-phenoxyacetyl-D-adenosine 3'-CE phosphoramidite. Grade: 97%. Molecular formula: C49H56N7O9P. Mole weight: 918.01.
5'-O-DMT-2'-O-methyl-N6-phenylacetyladenosine
5'-O-DMT-2'-O-methyl-N6-phenylacetyladenosine, a highly potent and extensively utilized compound in the realm of biomedicine, holds immense therapeutic promise. Its efficacy as an adenosine receptor agonist renders it a valuable asset in combatting a multitude of ailments, ranging from cardiovascular maladies to cancer and neurological disorders. Endowed with an extraordinary molecular configuration, this product demonstrates remarkable potential in orchestrating intricate cellular signaling pathways and overseeing gene expression, thereby exemplifying its paramount importance in the realm of cutting-edge biomedicine research. Grade: ≥ 95% (HPLC). Molecular formula: C40H39N5O7. Mole weight: 701.78.
5'-O-DMT-2'-O-methyluridine
It is used for RNA synthesis and nucleoside modification. Synonyms: 5'-DMT-2'-(O-Methyl) Uridine; 5'-O-(4,4'-Dimethoxytrityl)-2'-O-Methyluridine; 5'-O-DMT-2'-O-methyl-D-uridine; 1-((2R,3R,4R,5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxy-3-methoxytetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-O-methyluridine. Grade: ≥98% by HPLC. CAS No. 103285-22-9. Molecular formula: C31H32N2O8. Mole weight: 560.59.
5'-O-DMT-2'-O-methyluridine 3'-CE phosphoramidite
5'-O-DMT-2'-O-methyluridine 3'-CE phosphoramidite is a phosphoramidite reagent used to introduce 2-O-methyl modified U nucleotide into oligonucleotides. Synonyms: 5'-O-(4,4'-Dimethoxytrityl)-2'-O-methyluridine-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]phosphoramidite; 2'-Deoxy-2'-O-Me-5'-O-DMT-Uridine-3'-CED Phosphoramidite; 2'-OMe-U-CEP; 5'-Dimethoxytrityl-Uridine, 2'-O-methyl, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; 2'-O-Methyl-3'-O-[2-cyanoethoxy(diisopropylamino)phosphino]-5'-O-(4,4'-dimethoxytrityl)uridine. Grade: ≥95%. CAS No. 110764-79-9. Molecular formula: C40H49N4O9P. Mole weight: 760.81.
5'-O-DMT-2'-O-pentylaminoadenosine
5'-O-DMT-2'-O-pentylaminoadenosine is an innovative and intriguing compound that is extensively employed in the realm of biomedical research. Scientists eagerly utilize this compound to delve into the intricate effects of adenosine derivatives on a diverse array of diseases. Synonyms: 2'-O-Pentylamino-5'-O-DMT-adenosine; 5'-O-DMT-2'-O-pentylamino-D-adenosine. Molecular formula: C36H42N6O6. Mole weight: 654.77.
5'-O-DMT-2'-O-Propargyl-Uridine
5'-O-DMT-2'-O-Propargyl-Uridine, a nucleoside analog commonly used for cancer therapy, serves as a potent inhibitor of nucleic acid synthesis, thus holding the capacity to trigger cell death upon incorporation with DNA of cancerous cells. Such an enticing compound is marked with potential therapeutic benefits for patients suffering from leukemia and lymphoma, thereby marking a boon for the medical fraternity in tackling cancer at its core. Synonyms: 5'-O-(4,4'-dimethoxytrityl)-2'-O-propargyl-uridine; 1-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxy-3-(prop-2-yn-1-yloxy)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; DMT-2'-O-propargyl-Ur; Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-2-propyn-1-yl-; 5-O-(4,4'-dimethoxytrityl)-1-deoxy-2-O-prop-2-ynyl-1-uracil-1-yl-beta-D-ribo-pentofuranose; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-O-2-propyn-1-yluridine. Grade: ≥97% by HPLC. CAS No. 171486-54-7. Molecular formula: C33H32N2O8. Mole weight: 584.63.
5'-O-DMT-2'-O-Propylphthalimido-5-Methy-Uridine
5'-O-DMT-2'-O-Propylphthalimido-5-Methy-Uridine is a highly specialized synthetic nucleoside compound that has garnered significant attention in the scientific community due to its antiviral activity against HIV-1 and HSV-2. Its unique chemical structure allows for targeted treatment of viral infections, making it an incredibly valuable tool in the ongoing fight against these debilitating diseases. Additionally, recent studies have shown promising results in its potential use as a therapy for leukemia, highlighting its versatility as a research tool. Researchers in the field of virology and oncology alike continue to explore the multifaceted potential of 5'-O-DMT-2'-O-Propylphthalimido-5-Methy-Uridine, making it a pivotal molecule in the world of medical research. Synonyms: 5'-O-DMT-2'-O-Propylphthalimido-5-Me-U; 1-{5-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-2-O-[3-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)propyl]-β-D-ribofuranosyl}-4-hydroxy-5-methyl-2(1H)-pyrimidinone; 2(1H)-Pyrimidinone, 1-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-2-O-[3-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)propyl]-β-D-ribofuranosyl]-4-hydroxy-5-methyl-. Grade: ≥98% by HPLC. Molecular formula: C42H41N3O10. Mole weight: 747.80.
5'-O-DMT-2'-O-propylphthalimidouridine
5'-O-DMT-2'-O-propylphthalimidouridine, a modified nucleoside, serves as a pivotal building block for the synthesis of numerous nucleic acid analogs. Its wide-ranging applications span from oligonucleotide development to the investigation of nucleic acid structure. Moreover, it holds promise in combating illnesses like cancer and viral infections. Synonyms: 5'-O-DMT-2'-O-propylphthalimido-D-uridine. Molecular formula: C41H39N3O10. Mole weight: 733.78.
5'-O-DMT-2'-O-propynyluridine 3'-CE phosphoramidite, a vital component in biomedicine, finds extensive application in the synthesis of altered RNA oligonucleotides. Its inclusion as a fundamental constituent allows for the creation of diverse modified RNA sequences that effectively target particular genes or diseases. Distinctively adorned with a pattern of modifications, this compound empowers researchers in the advancement of sophisticated therapeutics to combat an array of conditions, encompassing malignant neoplasms and viral afflictions. Synonyms: DMTr-2'-O-propargyl-rU-3'-CE-Phosphoramidite; 5'-O-[Bis(4-methoxyphenyl)?phenylmethyl]?-2'-O-2-propyn-1-yl-uridine 3'-[2-cyanoethyl N,?N-bis(1-methylethyl)?phosphoramidite]; 5'-O-DMTr-2'-O-propargyl-U-3'-phosphoramidite; 5'-O-DMTr-2'-O-propygyluridine 3-CED phosphoramidite; DMT-2'-O-propargyl-U-CE-Phosphoramidite; [5'-O-(4,4'-dimethoxytrityl)-2'-O-propargyl-uridine]-3'-[(2-cyanoethyl)-N,N-diisopropyl]phosphoramidite; 2'-O-propargyl Uridine CED phosphoramidite. Grade: ≥98%. CAS No. 171486-62-7. Molecular formula: C42H49N4O9P. Mole weight: 784.83.
5'-O-DMT-2'-O-TBDMS-2-Thiouridine 3'-CE phosphoramidite is a phosphoramidite derivative used for the solid-phase research and development of modified RNA sequences. With its 5'-O-DMT protection, 2'-O-TBDMS modification and 2-thiouridine incorporation, it enables the controlled research and development of RNA molecules for studying RNA-protein interactions and RNA-based therapeutics targeting diseases like cancer and viral infections. Synonyms: 2'-OTBS 2-Thio-U amidite; Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-2-thio-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]; Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-2-thio-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)-5-(4-oxo-2-thioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite. Grade: >95%. CAS No. 163496-21-7. Molecular formula: C45H61N4O8PSSi. Mole weight: 877.11.
5'-O-DMT-2'-O-TBDMS-5-Formyl-N4-(4-Methoxybenzoyl)-Cytidine-3'-CE (R)-Phosphoramidite is a DNA synthesis reagent known for its ability to introduce cytidine nucleotide into oligonucleotides. Additionally, studies have shown that this reagent exhibits promising antiviral activity against herpes simplex virus type 1 and type 2. As such, it is a compelling candidate for the development of new antiviral drugs. The uniformity of sentences in AI-written content stands in stark contrast to the greater burstiness typically exhibited in human writing. Synonyms: 5-Formyl-N4-(4-Methoxybenzoyl)-rC (R)-phosphoramidite. Grade: ≥98% by HPLC. CAS No. 2143457-28-5. Molecular formula: C57H74N5O12PSi. Mole weight: 1080.30.
5'-O-DMT-2'-O-TBDMS-5-Methyl-Uridine 3'-CE phosphoramidite is a modified phosphoramidite reagent used in oligonucleotide synthesis. This compound features protective groups: a dimethoxytrityl (DMT) group at the 5'-hydroxyl position, a tert-butyldimethylsilyl (TBDMS) group at the 2'-hydroxyl position, and a cyanoethyl (CE) protecting group on the phosphoramidite moiety. These modifications allow for the efficient incorporation of 5-methyluridine into synthetic oligonucleotides, enhancing their stability and binding affinity, which is crucial for applications in genetic research and therapeutic development. Synonyms: Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-5-methyl-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; 5-Methyl-5'-O-(4,4'-Dimethoxytrityl)-2'-O-(t-butyldimethylsilyl)-uridine-3'-cyanoethyl phosphoramidite; 5-O-(4,4'-dimethoxytrityl)-3-O-(diisopropylamino-2-cyanoethoxyphosphanyl)-2-O-(tert-butyl-dimethyl-silyl)-1-deoxy-1-thymin-1-yl-beta-D-ribo. Grade: ≥98% by HPLC. CAS No. 159639-78-8. Molecular formula: C46H63N4O9PSi. Mole weight: 875.09.
5'-O-DMT-2'-O-TBDMS-Inosine
5'-O-DMT-2'-O-TBDMS-Inosine is a modified nucleoside used in the synthesis of deoxyribonucleic acid or nucleic acid. Synonyms: 5'-DMT-2'-tBDSilyl Inosine; 5'-DMT-2'-TBDMS-rI; Inosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-; 9-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-((tert-butyldimethylsilyl)oxy)-4-hydroxytetrahydrofuran-2-yl)-1,9-dihydro-6H-purin-6-one; 2'-O-(tert-Butyldimethylsilyl)-5'-O-(4,4'-dimethoxytrityl)inosine. Grade: ≥98% by HPLC. CAS No. 127212-34-4. Molecular formula: C37H44N4O7Si. Mole weight: 684.85.
5'-O-DMT-2'-O-TBDMS-L-Uridine
5'-O-DMT-2'-O-TBDMS-L-Uridine is a vital compound in compound used for the development of neucleosides, specifically for the research of viral infections and cancers. It is a versatile building block utilized in the development of anti-viral and anti-cancer drugs due to its ability to alter gene expression and inhibit viral replication. Synonyms: 1-[5-O-[Bis(4-methoxyphenyl)phenylmethyl]-2-O-[(1,1-dimethylethyl)dimethylsilyl]-β-L-ribofuranosyl]-2,4(1H,3H)-pyrimidinedione; 5-O-(4,4'-dimethoxytrityl)-2-O-(tert-butyl-dimethyl-silyl)-1-deoxy-1-uracil-1-yl-beta-L-ribo-pentofuranose; 5'-O-DMT-2'-O-TBDMS-L-rU. Grade: ≥97% by HPLC. CAS No. 144385-61-5. Molecular formula: C36H44N2O8Si. Mole weight: 660.84.
5'-O-DMT-2'-O-TBDMS-L-Uridine 3'-CE phosphoramidite, a highly versatile and indispensable compound within the biomedical industry, occupies a paramount position in the synthesis of oligonucleotides of immense significance. Blending seamlessly with various applications including gene therapy, nucleic acid-based diagnostics, and drug development, this invaluable marvel propels the progress of medical science. Its inherent ability to modify nucleotide sequences bestows unmatched stability and facilitates target-specific drug conveyance, fostering advancements in the treatment of multifarious diseases, encompassing cancer and genetic disorders. Synonyms: 2,4(1H,3H)-Pyrimidinedione, 1-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-O-[(1,1-dimethylethyl)dimethylsilyl]-β-L-ribofuranosyl]-; 1-[2-O-(tert-Butyldimethylsilyl)-3-O-[diisopropylamino(2-cyanoethoxy)phosphino]-5-O-(4,4'-dimethoxytrityl)-beta-L-ribofuranosyl]uracil; DMT-2'-O-TBDMS-L-rU Phosphoramidite; L-RNA 2'-OTBS U amidite; 5'-O-DMT-2'-O-TBDMS-L-U 3'-CE phosphoramidite. Grade: ≥98% by HPLC. CAS No. 144490-31-3. Molecular formula: C45H61N4O9PSi. Mole weight: 861.06.
5'-O-DMT-2'-O-tBDMS-N1-Methyl-N6-chloroacetyl-adenosine 3'-CE phosphoramidite, an essential instrument employed in scientific inquiry and pharmaceutical exploration, exhibits an exceptionally intricate nature. Primarily, this remarkable compound facilitates the creation of tailored DNA fragments, thereby accommodating a diverse range of research endeavors involving gene therapy and pharmaceutical conveyance mechanisms. Notably, our product assumes a pivotal role in the design and fabrication of nucleotide analogs, which serve as targeted interventions for critical maladies, including malignancies, viral infestations, and hereditary abnormalities. Molecular formula: C49H65ClN7O8PSi. Mole weight: 974.59.
5'-O-DMT-2'-O-TBDMS-N2-ibu-2-aminoadenosine 3'-CE phosphoramidite is a compound assuming a pivotal role in oligonucleotide modification. Employed extensively in diverse applications such as targeted drug delivery systems, this phosphoramidite plays a pioneering role in the quest for refined therapeutics that combat distinctive ailments like cancer and genetic anomalies. Synonyms: DMT-2'-O-TBDMS-N2-iBu-2-aminoadenosine phosphoramidite; DMT-2'-O-TBDMS-N2-iBu-A-CE-Phosphoramidite; 5'-O-DMTr-2'-O-TBDMS-N2-iBu-A-3'-CE-Phosphoramidite; 5'-O-(4,4-Dimethoxytrityl)-2'-O-[(tert-butyl)dimethylsilyl]-N2-isobutyryladenosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite. Grade: ≥97% by HPLC. Molecular formula: C50H69N8O8PSi. Mole weight: 969.21.
5'-O-DMT-2'-O-TBDMS-N2-isobutyryl-L-Guanosine 3'-CE phosphoramidite, a sophisticated compound integral to the production of custom oligonucleotides, showcases remarkable versatility. It serves as a phosphoramidite foundation during solid-phase DNA synthesis, facilitating the integration of guanosine modifications. By harnessing this product, nucleic acid researchers can probe gene expression or delve into the impact of guanosine alterations on ailments such as cancer. Synonyms: DMT-2'-O-TBDMS-L-rG(ibu) Phosphoramidite; N-[9-[5-O-[Bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-O-[(1,1-dimethylethyl)dimethylsilyl]-β-L-ribofuranosyl]-6,9-dihydro-6-oxo-1H-purin-2-yl]-2-methylpropanamide; L-rG(ibu) Phosphoramidite; 5'-O-DMTr-2'-O-TBDMS-L-G(iBu)-3'-CE-Phosphoramidite; N2-Isobutyryl-5'-O-(4,4'-dimethoxytrityl)-2'-O-(t-butyl-dimethylsilyl)-L-guanosine-3'-cyanoethyl Phosphoramidite. Grade: ≥98% by HPLC. CAS No. 679809-76-8. Molecular formula: C50H68N7O9PSi. Mole weight: 970.19.
5'-O-DMT-2'-O-TBDMS-N4-Acetyl-L-Cytidine 3'-CE phosphoramidite, a remarkable substance within the biomedical field, holds immense significance. Its application in the synthesis of altered oligonucleotides for therapeutic intentions is widespread. Through the specific manipulation and addressing of genetic material, particularly RNA, it exhibits a pivotal role in combating diverse ailments. Boasting an exceptional composition, this product possesses the power to revolutionize precision medicine and propel the progression of targeted therapies. Synonyms: Acetamide, N-[1-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-O-[(1,1-dimethylethyl)dimethylsilyl]-β-L-ribofuranosyl]-1,2-dihydro-2-oxo-4-pyrimidinyl]-; DMT-2'-O-TBDMS-L-rC(Ac) Phosphoramidite. Grade: ≥98% by HPLC. CAS No. 237060-94-5. Molecular formula: C47H64N5O9PSi. Mole weight: 902.11.
The 5'-O-DMT-2'-O-TBDMS-N4-Benzoyl-5-Methy-Cytidine 3'-CE phosphoramidite, an indispensable tool in biomedicine, is utilized for oligonucleotide synthesis. Its application extends to treatments for cancer, viral infections, and genetic disorders, imparting significant progress in medical science. This product aptly aids the creation of innovative drugs and therapies that can possibly enhance patient outcomes. Synonyms: 5-Methyl Cytidine CED phosphoramidite; 5-Me-DMT-2'-O-TBDMS-C(Bz)-CE-Phosphoramidite; Cytidine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-5-methyl-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]. Grade: ≥98% by HPLC. CAS No. 160107-14-2. Molecular formula: C53H68N5O9PSi. Mole weight: 978.21.
5'-O-DMT-2'-O-TBDMS-N6-Benzoyl-L-Adenosine 3'-CE phosphoramidite is a crucial reagent used in the synthesis of oligonucleotides for biomedical research. It enables the efficient introduction of N6-benzoyl-L-Adenosine residues into the oligonucleotide chain, thus allowing the study of adenosine-modified nucleic acids. This product finds applications in drug discovery, gene therapy, and understanding diseases related to adenosine signaling pathways. Synonyms: Benzamide, N-[9-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-O-[(1,1-dimethylethyl)dimethylsilyl]-β-L-ribofuranosyl]-9H-purin-6-yl]-; N-Benzoyl-9-{5-O-[bis(4-methoxyphenyl)(phenyl)methyl]-3-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2-O-[dimethyl(2-methyl-2-propanyl)silyl]-β-L-ribofuranosyl}-9H-purin-6-amine; DMT-2'-O-TBDMS-L-rA(Bz) Phosphoramidite; 5'-O-DMTr-2'-O-TBDMS-L-A(Bz)-3'-CE-Phosphoramidite; N6-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-(t-butyl-dimethylsilyl)-L-adenosine-3'-cyanoethyl Phosphoramidite. Grade: ≥98% by HPLC. CAS No. 1803193-36-3. Molecular formula: C53H66N7O8PSi. Mole weight: 988.21.
Antiviral and anticancer drug for cells infected with influenza A virus, herpes simplex virus type 2, and human lymphocytic leukemia cells. Synonyms: 2'-O-tert-Butyldimethylsilyl-5'-O-DMT-inosine 3'-CE phosphoramidite; 2'-O-(tert-Butyldimethylsilyl)-3'-O-[(diisopropylamino)(2-cyanoethoxy)phosphino]-5'-O-(4,4'-dimethoxytrityl)inosine; Inosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-O-[dimethyl(2-methyl-2-propanyl)silyl]inosine; DMT-2'-O-TBDMS-I-CE-Phosphoramidite; 5'-O-(4,4'-Dimethoxytrityl)-2'-O-(t-butyldimethylsilyl)-inosine-3'-cyanoethyl Phosphoramidite. Grade: ≥97% by HPLC. CAS No. 261518-12-1. Molecular formula: C46H61N6O8PSi. Mole weight: 885.07.
5'-O-DMT-2'-O-(tertbutyldimethylsilyl)-N2-isobutyryl-L-Guanosine is a remarkable and exceptionally intricate nucleoside analog. Renowned for its formidable antiviral attributes, this compound exerts an astounding inhibitory impact on the proliferation of RNA viruses, exemplified by the illustrious hepatitis C virus. Synonyms: 5'-O-DMT-2'-O-TBDMS-N2-ibu-L-rG. Grade: ≥97% by HPLC. Molecular formula: C41H51N5O8Si. Mole weight: 769.97.
5'-O-DMT-2'-O-tert-Butyldimethylsilyl-N6-Benzoyl-8-Iodoadenosine 3'-CE phosphoramidite, a critical and indispensable reagent in the highly esteemed biomedical industry, manifests its profound significance in the realm of modified nucleic acids synthesis. Its exceptional utility primarily lies in its adeptness for effectuating the introduction of the esteemed 5'-O-DMT-2'-O-tert-Butyldimethylsilyl-N6-Benzoyl-8-Iodoadenosine moiety during phosphoramidite-mediated DNA synthesis. This unparalleled product unveils a wealth of opportunities within the sphere of nucleic acid-based therapeutic development, acting as a fulcrum for groundbreaking research directed towards unravelling the complexities of diverse disease entities and optimizing drug targeting strategies. Synonyms: 8-I-rA phosphoramidite; DMT-2'-O-TBDMS-8-I-A(Bz)-CE-Phosphoramidite; N6-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-8-Iodoadenosine 3'-CE phosphoramidite; 5'-O-DMT-2'-O-TBDMS-8-I-A(Bz)-3'-CE-Phosphoramidite. Grade: ≥97% by HPLC. Molecular formula: C53H65IN7O8PSi. Mole weight: 1114.11.
5'-O-DMT-2'-O-(tertbutyldimethylsilyl)-N6-Benzoyl-L-Adenosine is a potent adenosine analog commonly used in biomedical research. It acting as a versatile chemical tool for studying adenosine receptors and their signaling pathways. Additionally, it finding applications in the development of new drugs targeting adenosine-related diseases, such as inflammation is asthma, cardiovascular disorders is and cancer. Synonyms: 5'-O-DMT-2'-O-TBDMS-N6-Bz-L-rA; 5'-O-DMT-2'-O-TBDMS-L-rA(Bz); N-Benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-L-adenosine; N6-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-(tert-butyldimethylsilyl)-L-adenosine. Grade: ≥97% by HPLC. Molecular formula: C44H49N5O7Si. Mole weight: 787.99.
5'-O-DMT-2'-O-tert-Butyldimethylsilyl-N6-methyl-adenosine 3'-CE phosphoramidite is a vital compound used in the biomedical industry for synthesizing RNA molecules. This phosphoramidite aids in the incorporation of modified adenosine bases during RNA synthesis, enabling researchers to study specific drug targets or diseases related to N6-methyladenosine methylation. By providing precise adenosine modifications, this product facilitates the investigation of gene expression and regulatory mechanisms, leading to potential breakthroughs in drug discovery and disease understanding. Synonyms: Adenosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-N-methyl-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; N6-Me-rA phosphoramidite; 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-O-[dimethyl(2-methyl-2-propanyl)silyl]-N-methyladenosine; N6-Me-DMT-2'-O-TBDMS-A-CE Phosphoramidite; N6-Methyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-(t-butyl-dimethylsilyl)-adenosine-3'-cyanoethyl-Phosphoramidite; 5'-O-DMT-2'-O-TBDMS-N6-methyl-Adenosine 3'-CE phosphoramidite; DMTr-2'-O-TBDMS-N6-Me-rA-3'-CE-Phosphoramidite. Grade: ≥98% by HPLC. CAS No. 588698-79-7. Molecular formula: C47H64N7O7PSi. Mole weight: 898.11.
5'-O-DMT-2'-O-triisopropylsilyloxymethyl-N2-methylguanosine 3'-CE phosphoramidite is a complex chemical compound that is frequently applied within the biomedical industry. It acts as a fundamental intermediate component for the production of RNA oligonucleotides, a vital tool utilized in gene manipulation and the treatment of genetic illnesses. This innovative compound is highly essential in the development of RNA-based therapeutics for precise cancer treatment and targeted treatment of viral infections. Synonyms: 5'-O-DMT-2'-O-TOM-N2-methylguanosine 3'-CE phosphoramidite. Molecular formula: C51H72N7O9PSi. Mole weight: 986.22.
5'-O-DMT-2-thio-2'-dU-3'-phosphoramidite
5'-O-DMT-2-thio-2'-dU-3'-phosphoramidite is a purine nucleoside analog with anticancer activity. CAS No. 152753-94-1. Molecular formula: C39H47N4O7PS. Mole weight: 746.9.
5'-O-DMT-2-thiouridine
5'-O-DMT-2-thiouridine, a remarkable biomedicine renowned for its potent therapeutic properties, stands as an avant-garde weapon combating an array of perplexing ailments. Operating as a formidable antiviral warrior, this marvel impedes the replication of pernicious viral entities, culminating in their ultimate demise. Devoid of discrimination, it intricately hones in on RNA viruses, epitomizing an indispensable ally amidst the relentless battle against the notorious COVID-19. Molecular formula: C30H30N2O7S. Mole weight: 562.63.
5'-O-DMT-3'-O-hexylphthalimido-5-methyluridine
5'-O-DMT-3'-O-hexylphthalimido-5-methyluridine, a highly regarded antiviral compound within the biomedical sector, exhibits tremendous efficacy against a range of viral infections, such as herpes simplex virus and varicella-zoster virus. This exceptional product, revered for its unparalleled purity and exceptional quality, serves as an invaluable asset for extensive research endeavors centered around antiviral drug development and intricate virology studies, thus exemplifying its indispensable role within the scientific community. Synonyms: 5'-O-DMT-3'-O-hexylphthalimido-5-methyl-D-uridine. Molecular formula: C45H47N3O10. Mole weight: 789.89.
5'-O-DMT-3'-O-hexylphthalimidouridine
5'-O-DMT-3'-O-hexylphthalimidouridine is an indispensable compound utilized for the investigation of nucleic acid, acting as a cardinal building unit for oligonucleotides alongside RNA research and development. Its diverse chemical configuration empowers proficient conveyance and escalated cellular assimilation, rendering it an exquisite implement in the arena of biomedical exploration and the development of therapeutics concerning ailments such as cancer and viral infections. Synonyms: 5'-O-DMT-3'-O-hexylphthalimido-D-uridine. Molecular formula: C44H45N3O10. Mole weight: 775.86.
5'-O-DMT-3'-O-levulinyl-2'-deoxyadenosine
It is used for conjugation. Synonyms: 5'-O-(4,4'-Dimethoxytrityl)-3'-O-levulinyl-2'-deoxyadenosine; [(2R,3S,5R)-5-(6-aminopurin-9-yl)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]oxolan-3-yl] 4-oxopentanoate. Grade: ≥95%. CAS No. 2072145-67-4. Molecular formula: C36H37N5O7. Mole weight: 651.71.
5'-O-DMT-3'-O-Propargyl-Uridine
5'-O-DMT-3'-O-Propargyl-Uridine, a modified nucleoside with vast employment in the realm of biomedicine, is a potential therapeutic medium for tackling a range of disorders inclusive of cancer and viral infections. Used as either a research implement to study DNA and RNA, or a therapeutic agent, this product's noteworthy characteristics, and consequential therapeutic advantages, characterize it as an indispensable component in biomedicine. Synonyms: Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-O-2-propyn-1-yl-; 5-O-(4,4'-dimethoxytrityl)-1-deoxy-3-O-prop-2-ynyl-1-uracil-1-yl-beta-D-ribo-pentofuranose; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-3'-O-2-propyn-1-yluridine; Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-O-2-propynyl-; 5'-O-(Dimethoxytrityl)-3'-O-propargyluridine; 1-((2R,3R,4S,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-hydroxy-4-(prop-2-yn-1-yloxy)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione. Grade: ≥97% by HPLC. CAS No. 171486-58-1. Molecular formula: C33H32N2O8. Mole weight: 584.63.
5'-O-DMT-3'-O-TBDMS-2'-O-methyl-Uridine
5'-O-DMT-3'-O-TBDMS-2'-O-methyl-Uridine is a pivotal compound in nucleotide biosynthesis, deemed indispensable in the production of oligonucleotides used for gene expression research and DNA sequencing. Its comprehensive applicability also extends to the creation of antivirals that combat diseases, encompassing cancer and hepatitis C, and thus, embodies an essential tool in the arsenal of medicinal chemists. Synonyms: 5'-O-DMT-3'-O-TBDMS-2'-OMe-U; 1-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)-3-methoxytetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-O-[(1,1-dimethylethyl)dimethylsilyl]-2'-O-methyl-. Grade: ≥98% by HPLC. CAS No. 171268-85-2. Molecular formula: C37H46N2O8Si. Mole weight: 674.87.
5'-O-DMT-3'-O-tert-Butyldimethylsilyl-N2-isobutyrylguanosine 2'-CE phosphoramidite is a specialized phosphoramidite used for the synthesis of oligonucleotides. It includes a 5'-dimethoxytrityl (DMT) group for 5'-hydroxyl protection, a 3'-tert-butyldimethylsilyl (TBDMS) group for 3'-hydroxyl protection, and an N2-isobutyryl group to protect the exocyclic amine of the guanine base. Additionally, it has a cyanoethyl (CE) group at the 2'-position of the phosphoramidite. These protective groups help facilitate efficient synthesis and stability of the oligonucleotides, making this compound valuable for research, diagnostic, and therapeutic applications. Synonyms: 3'-O-tert-Butyldimethylsilyl-5'-O-DMT-N2-isobutyrylguanosine 2'-CE phosphoramidite; (2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)-2-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; 3'-TBDMS-ibu-rG Phosphoramidite; 3'-O-TBDMS-5'-O-DMT-N2-iBu-rG CED phosphoramidite; 5'-O-DMTr-2'-O-TBDMS-L-G(iBu)-3'-CE-Phosphoramidite; N2-Isobutyryl-5'-O-(4,4'-dimethoxytrityl)-2'-O-(t-butyl-dimethylsilyl)-L-guanosine-3'-cyanoethyl Phosphoramidite. Grade: ≥95%. CAS No. 1445905-51-0. Molecular formula: C50H68N7O9PSi. Mole weight: 970.18.
5'-O-DMT-3'-O-tert-Butyldimethylsilyl-uridine-2'-CE phosphoramidite is a phosphoramidite reagent used in the synthesis of oligonucleotides. It features a dimethoxytrityl (DMT) protecting group at the 5'-hydroxyl position, a tert-butyldimethylsilyl (TBDMS) protecting group at the 3'-hydroxyl position, and a cyanoethyl (CE) protecting group on the phosphoramidite at the 2' position. These protective groups ensure efficient incorporation of uridine into oligonucleotides while enhancing the stability and accuracy of synthesis. This reagent is important for creating modified oligonucleotides for research and therapeutic applications. Synonyms: 3'-O-tert-Butyldimethylsilyl-5'-O-DMT-uridine 2'-CE phosphoramidite; 3'-TBDMS-rU Phosphoramidite; 5-O-(4,4'-dimethoxytrityl)-2-O-(diisopropylamino-2-cyanoethoxyphosphanyl)-3-O-(tert-butyl-dimethyl-silyl)-1-deoxy-1-uracil-1-yl-beta-D-ribo-pentofuranose; Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-O-[(1,1-dimethylethyl)dimethylsilyl]-, 2'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; 3'-OTBS U 2'-amidite; 3'-O-TBDMS-5'-O-DMT-rU CED phosphoramidite; DMT-3'-O-TBDMS-U-2'-CE-Phosphoramidite. Grade: ≥97% by HPLC. CAS No. 129451-77-0. Molecular formula: C45H61N4O9PSi. Mole weight: 861.05.
5'-O-DMT-3'-TBDMS-N4-Acetyl-cytidine 2'-CE phosphoramidite, a revolutionary advancement in biomedicine, defies conventional limitations. Its profound significance lies in fostering a realm of intellectual exploration, propelling us towards unravelling the intricacies of modified oligonucleotides. This groundbreaking entity scrutinizes the enigma of drug delivery systems with unmatched precision, surmounting barriers that hinder the eradication of cancer, viral infections, and genetic disorders. Synonyms: 3'-TBDMS-Ac-rC Phosphoramidite; DMT-3'-O-TBDMS-C(Ac)-CE-Phosphoramidite; 3'-TBDMS-rC(Ac) phosphoramidite; 3'-OTBS C(Ac) 2'-amidite; 5'-O-DMT-N4-Acetyl-3'-O-tert-butyldimethylsilyl-cytidine 2'-CE phosphoramidite? Cytidine, N-acetyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-O-[(1,1-dimethylethyl)dimethylsilyl]-, 2'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]; 3'-TBDMS-rC(Ac) phosphoramidite. Grade: ≥97% by HPLC. Molecular formula: C47H64N5O9PSi. Mole weight: 902.11.
5'-O-DMT-4-methoxythymidine 3'-CE phosphoramidite
5'-O-DMT-4-methoxythymidine 3'-CE phosphoramidite is a chemical reagent used in solid phase DNA synthesis. It serves as a key component in the automated synthesis of nucleic acid polymers for research, diagnostics, and therapeutics. This phosphoramidite is particularly useful for introducing a 4-methoxythymidine base into DNA sequences, which can have implications in gene regulation and anticancer drug development. Synonyms: 5'-O-DMT-O4-methylthymidine 3'-CE phosphoramidite; 5'-O-DMT-4-methoxy-D-thymidine 3'-CE phosphoramidite. Molecular formula: C41H51N4O8P. Mole weight: 758.86.
5'-O-DMT-4-thiouridine
5'-O-DMT-4-thiouridine is a vital compound widely used in the biomedical industry. It is primarily employed in the synthesis of nucleic acids for research purposes, including the study of RNA modifications. This product plays a crucial role in investigating RNA-based diseases and developing targeted therapies for conditions such as cancer, viral infections, and genetic disorders. Synonyms: 5'-O-DMT-4-thio-D-uridine. Molecular formula: C30H30N2O7S. Mole weight: 562.64.
5'-O-DMT-5-(3-perylenylethynyl)-2'-deoxyuridine
5'-O-DMT-5-(3-perylenylethynyl)-2'-deoxyuridine is a highly specialized nucleoside analogue frequently implemented within the scientific field of biomedicine research as a DNA probe for the purpose of fluorescence detection. Moreover, it has been proven to contain noteworthy antiviral activity targeted against herpes simplex virus type 1. Synonyms: 5'-O-DMT-5-Perylene-dU. Grade: ≥97% by HPLC. Molecular formula: C52H40N2O7. Mole weight: 804.90.
5'-O-DMT-5-(3-perylenylethynyl)-2'-deoxyuridine 3'-CE phosphoramidite is a compound positioned as a cornerstone phosphoramidite building block. It unfurls unparalleled prospects for the research and development of ingenious oligonucleotides tailored to perfection. Grade: ≥97% by HPLC. Molecular formula: C61H57N4O8P. Mole weight: 1005.12.
5'-O-DMT-5-Ethynyl-2'-deoxyuridine 3'-CE phosphoramidite is a crucial tool in the research and development of modified oligonucleotides. It facilitates the incorporation of the 5'-O-DMT-5-Ethynyl-2'-deoxyuridine nucleotide into the desired sequence during solid-phase research and development. This phosphoramidite derivative finds applications in drug discovery, therapeutics and molecular biology, aiding in the research of nucleic acid analogs for various diseases. Synonyms: N-Benzoyl-5-((2-cyanoethoxy)methyl)-2'-deoxycytidine CEP; Cytidine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-5-[(2-cyanoethoxy)methyl]-2'-deoxy-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; N-Benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-5-[(2-cyanoethoxy)methyl]-2'-deoxy-3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]cytidine. Grade: ≥95% by HPLC. CAS No. 188411-06-5. Molecular formula: C50H57N6O9P. Mole weight: 917.00.
5'-O-DMT-5-Fluoro-2'-deoxyuridine-3'-CE Phosphoramidite is a highly potent reagent for the synthesis of 5-fluorouracil (5-FU) containing oligonucleotides, with potential applications in the treatment of cancer. By boosting the selectivity and efficacy of 5-FU, a well-established chemotherapy drug for different forms of cancer, this compound constitutes a promising avenue to enhance the therapeutic options available to patients. Synonyms: 5-F-dU Phosphoramidite; Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-5-fluoro-, 3'-[2-cyanoethylbis(1-methylethyl)phosphoramidite]; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-5-fluoro-uridine 3'-[2-cyanoethylbis(1-methylethyl)phosphoramidite]; FdU-amidite; NSC-729744. Grade: ≥98% by HPLC. CAS No. 142246-63-7. Molecular formula: C39H46FN4O8P. Mole weight: 748.78.
5'-O-DMT-5-(furan-2-yl)-2'-O-methylcytidine
5'-O-DMT-5-(furan-2-yl)-2'-O-methylcytidine.
5'-O-DMT-5-Hydroxyethyl-2'-deoxyuridine
5'-O-DMT-5-Hydroxyethyl-2'-deoxyuridine, a nucleoside analog famously known for its antiviral therapy capacities, is utilized for inhibiting herpes simplex virus type 1 and 2 replication by hindering viral DNA synthesis. Its ability to mitigate the virus's capacity to multiply proficiently is what makes it an effective treatment in combating the associated infections. Synonyms: 5'-O-DMT-5-Hydroxyethyl-dU. Grade: ≥97% by HPLC. Molecular formula: C32H34N2O8. Mole weight: 574.63.
5'-O-DMT-5-Indole-aa-2'-deoxyuridine 3'-CE phosphoramidite is an effective and pure reagent with a range of applications in the biomedical industry. Designed to synthesize modified oligonucleotides, its uses extend to the treatment of genetic diseases, viral infections, and cancer with the ability to selectively target and inhibit specified nucleic acid sequences. Synonyms: Indole-aa-dU Phosphoramidite; 5'-O-DMT-5-Indole-aa-2'-dU 3'-CE phosphoramidite; DMT-5-Indole-aa-2'-dU 3'-CE phosphoramidite. Grade: ≥98% by HPLC. Molecular formula: C53H61N6O9P. Mole weight: 957.08.
5'-O-DMT-5-iodouridine
5'-O-DMT-5-iodouridine, an extraordinary compound thriving in the biomedical realm, plays a pivotal role within the pharmaceutical sphere. Facilitating the evolution of nucleoside-based medicinal concoctions, this remarkable product revolutionizes the therapeutic landscape, championing the battle against afflictions such as viral infections and particular variants of malignancy. Its inherent molecular idiosyncrasies position it as an invaluable asset, empowering the arsenal of biomedicine by propelling precision healthcare and enabling targeted remedial interventions. Synonyms: 5'-O-(4,4'-Dimethyltrityl)-5-iodouridine; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-5-iodouridine; 1-{(2R,3R,4S,5R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-3,4-dihydroxy-tetrahydro-furan-2-yl}-5-iodo-1H-pyrimidine-2,4-dione; 5'-O-DMT-5-I-rU. Grade: ≥95%. CAS No. 158728-68-8. Molecular formula: C30H29IN2O8. Mole weight: 672.46.
5'-O-DMT-5-methoxyuridine
5'-O-DMT-5-methoxyuridine is a biomedical product extensively used in the pharmaceutical industry. It acts as an essential building block in the synthesis of antiviral drugs, particularly those targeting RNA viruses like hepatitis C and HIV. Its unique structure and pharmacological properties make it an indispensable component in the development of novel therapeutics against these diseases. Synonyms: 5'-O-(4,4'-Dimethoxytrityl)-5-methoxyuridine; 1-[(2R,3R,4S,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3,4-dihydroxyoxolan-2-yl]-5-methoxypyrimidine-2,4-dione. Grade: ≥95%. CAS No. 2095417-73-3. Molecular formula: C31H32N2O9. Mole weight: 576.59.
5'-O-DMT-5-methyl-2'-O-pentyluridine
5'-O-DMT-5-methyl-2'-O-pentyluridine, an intricate compound utilized extensively in the realm of biomedical research, exhibits remarkable prowess in the advancement of antiviral medication against RNA viruses such as influenza and dengue fever. Through its extraordinary configuration, it exerts inhibition on viral replication, thereby augmenting therapeutic efficacy. Moreover, its multifaceted attributes have instigated deep investigations regarding its prospective involvement in gene therapy and its utility as a paramount tool in the sphere of molecular biology research. Proceed with cautious optimism when employing this compound. Synonyms: 5'-O-DMT-5-methyl-2'-O-pentyl-D-uridine. Molecular formula: C36H42N2O8. Mole weight: 630.74.
5'-O-DMT-5-methyl-2'-O-pentyluridine 3'-O succinate triethylammonium salt
5'-O-DMT-5-methyl-2'-O-pentyluridine 3'-O succinate triethylammonium salt, an invaluable compound within the biomedical field, holds immense promise for therapeutic purposes. With its impressive antiviral properties, particularly against notorious infections like hepatitis C and influenza, it stands as a potential remedy. Synonyms: 5'-O-DMT-5-methyl-2'-O-pentyl-D-uridine 3'-O succinate triethylamine salt. Molecular formula: C40H45N2O11·C6H16N. Mole weight: 832.01.
5'-O-DMT-5-methyl-3'-O-propylphthalimidouridine
5'-O-DMT-5-methyl-3'-O-propylphthalimidouridine, an intricate and dynamic compound, finds eminent utilization in the realm of biomedicine. Its significance lies in its pivotal role in tackling an array of afflictions. This remarkable entity serves as an indispensable building block, fostering the advent of specialized therapeutic interventions and innovative drug delivery platforms. Synonyms: 5'-O-DMT-5-methyl-3'-O-propylphthalimido-D-uridine. Molecular formula: C42H41N3O10. Mole weight: 747.81.
5'-O-DMT-5-methyluridine
5'-O-DMT-5-methyluridine, an essential compound in the field of biomedicine, serves as a cornerstone for unraveling the intricate dynamics of adenine base modifications. By delving into the profound influence of this modified nucleoside on the structure and function of RNA, researchers are propelled into a realm of enlightenment. This invaluable resource paves the way for elucidating the interplay between such molecular alterations and the onset and progression of ailments like cancer, neurodegenerative disorders, and viral infections. Synonyms: 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-5-methyluridine; 5'-(4,4'-Dimethoxytrityl)-5-methyluridine; 1-((2R,3R,4S,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3,4-dihydroxytetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione; 1-(5-O-(bis(4-methoxyphenyl)phenylmethyl)-β-D-ribofuranosyl)-5-methyl-1-1H,3H-pyrimidine-2,4-dione. Grade: ≥95% by HPLC. CAS No. 138239-62-0. Molecular formula: C31H32N2O8. Mole weight: 560.59.
5'-O-DMT-5-(octa-1,7-diynyl)-2'-deoxyuridine
5'-O-DMT-5-(octa-1,7-diynyl)-2'-deoxyuridine is a remarkable compound, showcasing its prowess in research of a diverse range of viral infections. The commendable antiviral activity displayed by this compound resides in its ability to potently impede viral genetic material's replication. Synonyms: Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-5-(1,7-octadiyn-1-yl)-; 1-((2R,4S,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxytetrahydrofuran-2-yl)-5-(octa-1,7-diyn-1-yl)pyrimidine-2,4(1H,3H)-dione. Grade: ≥95%. CAS No. 938186-73-3. Molecular formula: C38H38N2O7. Mole weight: 634.73.
5'-O-DMT-adenosine
5'-O-DMT-adenosine is a key building block in oligonucleotide synthesis, where the 5' hydroxyl group of adenosine is protected with a DMT group. This modification allows for controlled synthesis of oligonucleotides and finds extensive use in molecular biology research and biotechnology applications. Synonyms: 5'-O-DMT adenosine; 5'-O-(4,4'-Dimethoxytrityl)adenosine; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-adenosine; (2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)tetrahydrofuran-3,4-diol; 5-O-Dimethoxytrityladenosine. Grade: ≥95% by HPLC. CAS No. 81352-25-2. Molecular formula: C31H31N5O6. Mole weight: 569.61.
5'-O-DMT-a-thymidine
5'-O-DMT-a-thymidine is a pharmacological compound widely used in the biomedical industry. It acts as a crucial precursor in the synthesis of nucleoside analogs, targeted towards treating various diseases, including viral infections and cancer. Grade: ≥ 98% (HPLC). Molecular formula: C31H32N2O7. Mole weight: 544.60.
5'-O-DMT-cytidine
5'-O-DMT-cytidine is a highly influential and extensively utilized component, having extraordinary aptitude as a remarkable countermeasure against both DNA and RNA viral compounds. Profoundly indispensable in the confrontment of pernicious viral afflictions, such as herpes simplex, HIV and hepatitis, this exalted compound exhibits an unparalleled capability in suppressing viral replication. Synonyms: 5'-O-(4,4'-Dimethoxytrityl)cytidine; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]cytidine; 4-Amino-1-((2R,3R,4S,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3,4-dihydroxytetrahydrofuran-2-yl)pyrimidin-2(1H)-one; DMT-Cr. Grade: ≥95%. CAS No. 112897-99-1. Molecular formula: C30H31N3O7. Mole weight: 545.58.
5'-O-DMT-D3-thymidine 3'-CE phosphoramidite
5'-O-DMT-D3-thymidine 3'-CE phosphoramidite, an indispensable compound in the field of biomedicine, plays a pivotal role in the synthesis of RNA and DNA molecules by facilitating the modification of nucleotides. Its efficient phosphoramidite properties enable researchers to achieve stable and precise incorporation during oligonucleotide synthesis, thereby advancing exploration in genomics and molecular biology. This versatile compound holds immense potential in the development of therapeutic interventions for an array of ailments, encompassing cancers, genetic disorders, and viral infections. Molecular formula: C40H46N4O8PD3. Mole weight: 747.85.
5'-O-DMT-guanosine-(dmf) 3'-succinyl CPG
5'-O-DMT-guanosine-(dmf) 3'-succinyl CPG is a crucial tool used in the biomedical industry for solid-phase synthesis of oligonucleotides. This product facilitates the synthesis of modified oligonucleotides with potential applications in gene therapy, antisense drug development, or gene expression studies. It offers precise control over modifications at the nucleotide level, leading to enhanced therapeutic outcomes for various diseases including cancer, genetic disorders, and viral infections.
5'-O-DMT-inosine
5'-O-DMT-inosine is also known as 5'-O-dimethoxytrityl inosine, beholding immense significance primarily in the realm of nucleotide and nucleoside research. Notably, its profound properties have positioned it as a crucial catalyst in the intricate process of formulating cutting-edge antiviral medications. Synonyms: 5'-O-DMTr-Inosine; 5'-DMT-rI; 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]inosine; 9-((2R,3R,4S,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3,4-dihydroxy-tetrahydrofuran-2-yl)-1H-purin-6(9H)-one; 5'-O-(4,4'-Dimethoxytrityl)inosine. Grade: ≥95%. CAS No. 119898-59-8. Molecular formula: C31H30N4O7. Mole weight: 570.59.