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Coumamidine γ1
It is produced by the strain of Saccharopolyspora sp. AB 1167L-65. It is a kind of alkaline water-soluble sugar Cinodine antibiotic, which has broad spectrum antibacterial activity and also has effect on pseudomonas aeruginosa. Synonyms: Coumamidine gamma1; Coumamidine gamma(1). CAS No. 121634-35-3. Molecular formula: C33H49N13O13. Mole weight: 835.82.
Coumamidine γ2
It is produced by the strain of Saccharopolyspora sp. AB 1167L-65. It is a kind of alkaline water-soluble sugar Cinodine antibiotic, which has broad spectrum antibacterial activity and also has effect on pseudomonas aeruginosa. Synonyms: Coumamidine gamma2; Coumamidine gamma(2). CAS No. 121634-34-2. Molecular formula: C33H49N13O13. Mole weight: 835.82.
Coumermycin A1
Coumemycin A1 is found to bind at a second ATP-binding site in the C-terminal domain of Hsp90, IC50 70 μmol/L. It is produced by the strain of Streptomyces rishirensis, Str. spinichromogene and Str. Spinicoumarensis. It has anti-gram positive bacteria, negative bacteria, mycobacterium (weak) activity, cross-resistance with Novobiocin. Uses: Topoisomerase ii inhibitors. Synonyms: coumermycin a1; Coumamycine; Coumamycinum; Cumamicina; Notomycin; Coumamycin; Notomycin A1; Sugordomycin D-1a; Sugordomycin; Antibiotic Bu-620. Grades: >98%. CAS No. 4434-5-3. Molecular formula: C55H59N5O20. Mole weight: 1110.09.
CP-120509
It is produced by the strain of Actinomadura roseorufa 263606. CP-120509 has anti-gram-positive bacteria, spirochete and spirochete activity, and also has a good anti-coccidiosis effect caused by Eimeria acervulina, E. tenella. Molecular formula: C45H76O17. Mole weight: 889.07.
CP-225917
CP-225917 inhibits Ras farnesyl transferase from the mouse brain and Squalene synthase. Molecular formula: C31H38O10. Mole weight: 570.63.
CP-263114
CP-263114 inhibits Ras farnesyl transferase from the mouse brain and Squalene synthase. CAS No. 186700-09-4. Molecular formula: C31H36O9. Mole weight: 552.61.
CP-35587
CP-35587 is resistant to gram-positive cocci, but it has no effect on penicillin-resistant Staphylococcus aureus and is active against gram-negative bacteria. Synonyms: Benzeneacetamide, alpha-amino-N-(3,3-dimethyl-7-oxo-2-(1H-tetrazol-5-yl)-4-thia-1-azabicyclo(3.2.0)hept-6-yl)-4-hydroxy-, (2S-(2alpha,5alpha,6beta))-. CAS No. 57089-17-5. Molecular formula: C16H19N7O3S. Mole weight: 389.43.
CP 412065
It is originally isolated from Hericium ramosum CL 24240. CP 412065 selectively inhibited κ-opioid receptor binding with IC50 > 200 μnmol/L. Synonyms: Antibiotic CP 412065. Molecular formula: C25H34O6. Mole weight: 430.53.
CP-82009
CP-82009 is a polyether antibiotic originally isolated from Actinomadura sp. It shows strong resistance to chicken coccidiosis, and also has anti-gram-positive bacteria and spirochetes activity. Molecular formula: C49H84O17. Mole weight: 945.18.
CP 91243
CP 91243 is a polyether antibiotic originally isolated from Actinomadura roseorufa. It has anti-gram-positive bacteria, spirochete, treponema activity, and it also has the effect on chicken coccidiosis. CAS No. 135179-21-4. Molecular formula: C50H84O18. Mole weight: 973.19.
CP 91244
CP 91244 is a polyether antibiotic originally isolated from Actinomadura roseorufa. It has anti-gram-positive bacteria, spirochete, treponema activity, and it also has the effect on chicken coccidiosis. Synonyms: Semduramicin, 5-O-(tetrahydro-5-hydroxy-6-methyl-2H-pyran-2-yl)-, (5(2S,5S,6R))-. CAS No. 135215-73-5. Molecular formula: C51H86O18. Mole weight: 987.21.
C-Peptide, dog
C-Peptide, dog is a component of proinsulin. C-peptide is a marker of insulin secretion in understanding the pathophysiology of type 1 and type 2 diabetes. Synonyms: C-Peptide (dog). Grades: >95% by HPLC. CAS No. 39016-05-2. Molecular formula: C137H225N37O49. Mole weight: 3174.47.
Cremeomycin
It is produced by the strain of Streptomyces cremeus. It has anti-gram-positive bacteria, negative bacteria, fungi (weak) activity, and has the effect of inhibiting the leukemic cell L-1210 (IC50 is 1.5 μg/mL). Synonyms: Antibiotic U-23643. Molecular formula: C8H6N2O4. Mole weight: 194.14.
Cremimycin
It is produced by the strain of Streptomyces sp. MJ635-86F6. It has anti-gram-positive bacteria activity including methicillin-resistant staphylococcus aureus (MRSA), MIC is 0.2-0.39 μg/mL. It showed cytotoxicity to mouse tumor cell lines P388, L1210, IMC, S180, B16 and SS3 in vitro. Synonyms: Cremimycin (antibiotic); Cyclopent(I)azacyclononadecene-7,11,17(8H,12H,19H)-trione,9,10,13,14,15,16,20,20a-octahydro-19-((2,6-dideoxy-3-O-methylhexopyranosyl)oxy)-15,18-dihydroxy-9-hexyl-2-methyl-. CAS No. 182285-29-6. Molecular formula: C35H53NO9. Mole weight: 631.79.
Crinipellin A
It is produced by the strain of Crinipellis stipitaria. It has anti-gram-positive bacteria and Aldrin ascites carcinoma activity. Synonyms: (1R,3R,6S,8R,9S,11R,12R,13R)-8-hydroxy-7a,9a-dimethyl-3-methylidene-7-(propan-2-yl)hexahydro-1aH,5H-pentaleno[6a',1':5,6]pentaleno[1,6a-b]oxirene-2,9(3H,9aH)-dione. CAS No. 97294-60-5. Molecular formula: C20H26O4. Mole weight: 330.42.
Crinipellin B
It is produced by the strain of Crinipellis stipitaria. It has anti-gram-positive bacteria and Aldrin ascites carcinoma activity. Synonyms: (1aS,3aR,4aS,7R,7aR,9R,9aR,9bR)-9-hydroxy-7-isopropyl-7a,9a-dimethyl-3-methyleneoctahydro-3H,8H-pentaleno[6a',1':5,6]pentaleno[1,6a-b]oxirene-2,8(1aH)-dione. CAS No. 97294-61-6. Molecular formula: C20H26O4. Mole weight: 330.42.
Crisamicin A
It is produced by the strain of Micromonospora purpureochromogenes subsp. lalotolerans. It only has activity against gram-positive bacteria. The activity of samicin C is stronger than Crisamicin A. Synonyms: (3aS)-5β, 5'β-Dimethyl-10, 10'-dihydroxy-3, 3', 3aβ, 3'aβ, 5, 5', 6, 6', 11, 11', 11bβ, 11'bβ-dodecahydro-8, 8'-bi[2H-furo[3, 2-b]naphtho[2, 3-d]pyran]-2, 2', 6, 6', 11, 11'-hexaone; (3aS,3'aS,5S,5'S,11bS,11'bS)-3,3',3a,3'a,5,5',11b,11'b-Octahydro-10,10'-dihydroxy-5,5'-dimethyl-8,8'-bi[2H-furo[3,2-b]naphtho[2,3-d]pyran]-2,2',6,6',11,11'-hexone; CRS-A; (8,8'-Bi-2H-furo(3,2-b)naphtho(2,3-d)pyran)-2,2',6,6'11,11'-hexone,3,3',3a,3'a,5,5',11b,11'b-octahydro-10,10'-dihydroxy-5,5'-dimethyl-, (3aS-(3aalpha, 5alpha, 8(3aR*, 5R*, 11bR*), 11balpha))-. CAS No. 95828-47-0. Molecular formula: C32H22O12. Mole weight: 598.51.
Crisamicin C
It is produced by the strain of Micromonospora purpureochromogenes subsp. lalotolerans. It only has activity against gram-positive bacteria. The activity of samicin C is stronger than Crisamicin A. Synonyms: CRS-C. CAS No. 100630-79-3. Molecular formula: C32H22O13. Mole weight: 614.51.
Cristatic acid
It is produced by the strain of Albaterllus cristatus. It can resist bacillus, tumor and hemolysis. Synonyms: NSC338268; NSC 338268; Cristatic acid-1. CAS No. 80557-13-7. Molecular formula: C23H28O5. Mole weight: 384.46.
CRM-51005
It is a phospholipase C (PLC) inhibitor originally isolated from fungal MT51005. Synonyms: Benzaldehyde, 3-ethyl-2,4-dihydroxy-6-((1E)-1-methyl-1-pentenyl)-; Benzaldehyde, 3-ethyl-2,4-dihydroxy-6-(1-methyl-1-pentenyl)-, (E)-; 3-ethyl-6-[(E)-hex-2-en-2-yl]-2,4-dihydroxybenzaldehyde. CAS No. 203051-01-8. Molecular formula: C15H20O3. Mole weight: 248.32.
CRM646-A
It is originally isolated from Acremonium sp. MT70646. CRM646-A had a strong inhibitory effect on the movement of B16-H10 melanoma cells with IC50 of 15 μmol/L. Synonyms: CRM-646-A; CHEMBL3347523. Molecular formula: C36H50O13. Mole weight: 690.77.
CRM646-B
It is originally isolated from Acremonium sp. MT70646. CRM646-B had a strong inhibitory effect on the movement of B16-H10 melanoma cells with IC50 of 30 μmol/L. Synonyms: CRM-646-B; 4-[(4-Carboxy-3-hydroxy-5-methylphenoxy)carbonyl]-3-hydroxy-5-pentadecylphenyl methyl β-D-glucopyranosiduronate. Molecular formula: C37H52O13. Mole weight: 704.80.
Crocacin A
It is produced by the strain of Chondromyces crocatus sp. Cm c3. It has anti-yeast and filamentous fungal activity. It can inhibit mouse fibroblasts L929 (MIC is 0.2 ng). In the microsomes of the calf's heart, it can interrupt the bc1 segment of electronic transmission, causes redshift of 569nm peak in cytochrome B reduction spectrum. Synonyms: (+)-CrocainA; [(2Z,5Z)-6-((6S,7S,8S,9S)-(2E,4E,10E)-7,9-Dimethoxy-3,6,8-trimethyl-11-phenyl-undeca-2,4,10-trienoylamino)-hexa-2,5-dienoylamino]-acetic acid, methyl ester; Methyl 2-[6-((2E,4E,10E)(6S,7S,9S,8R)-7,9-dimethoxy-3,6,8-trimethyl-11-phenylundeca-2,4,10-trienoylamino)(2Z,5Z)hexa-2,5-dienoylamino]acetate. CAS No. 157698-34-5. Molecular formula: C31H42N2O6. Mole weight: 538.67.
Crocacin B
It is produced by the strain of Chondromyces crocatus sp. Cm c3. It has anti-yeast and filamentous fungal activity. It can inhibit mouse fibroblasts L929 (MIC is 0.2 ng). In the microsomes of the calf's heart, it can interrupt the bc1 segment of electronic transmission, causes redshift of 569nm peak in cytochrome B reduction spectrum. Synonyms: [[(2Z,5Z)-6-[[(2E,4E,6S,7S,8R,9S,10E)-7,9-Dimethoxy-3,6,8-trimethyl-1-oxo-11-phenyl-2,4,10-undecatrienyl]amino]-1-oxo-2,5-hexadienyl]amino]acetic acid; 2-[6-((2E,4E,10E)(6S,7S,9S,8R)-7,9-Dimethoxy-3,6,8-trimethyl-11-phenylundeca-2,4,10-trienoylamino)(2Z,5Z)hexa-2,5-dienoylamino]acetic acid. CAS No. 237425-37-5. Molecular formula: C30H40N2O6. Mole weight: 524.65.
Crocacin C
It is produced by the strain of Chondromyces crocatus sp. Cm c3. It has anti-yeast and filamentous fungal activity. It can inhibit mouse fibroblasts L929 (MIC is 0.2 ng). In the microsomes of the calf's heart, it can interrupt the bc1 segment of electronic transmission, causes redshift of 569nm peak in cytochrome B reduction spectrum. Synonyms: (+)-Crocacin C; (2E,4E,10E)(6S,7S,9S,8R)-7,9-Dimethoxy-3,6,8-trimethyl-11-phenylundeca-2,4,10-trienamide; 7,9-dimethoxy-3,6,8-trimethyl-11-phenyl-(2E,4E,6S,7S,8R,9S,10E)-2,4,10-undecatrienamide. CAS No. 237425-38-6. Molecular formula: C22H31NO3. Mole weight: 357.49.
Crocacin D
It is produced by the strain of Chondromyces crocatus sp. Cm c3. It has anti-yeast and filamentous fungal activity. It can inhibit mouse fibroblasts L929 (MIC is 0.2 ng). In the microsomes of the calf's heart, it can interrupt the bc1 segment of electronic transmission, causes redshift of 569nm peak in cytochrome B reduction spectrum. Synonyms: (+)-Crocacin D. CAS No. 237425-39-7. Molecular formula: C31H44N2O6. Mole weight: 540.69.
Cryptoporic acid A
It is produced by the strain of Cryptoporus volvatus. Synonyms: (2R,3S)-3-Methoxycarbonyl-2-((1S,4aS,8aS)-5,5,8a-trimethyl-2-methylene-decahydro-naphthalen-1-ylmethoxy)-pentanedioic acid 1-methyl ester. CAS No. 113592-87-3. Molecular formula: C22H36O7. Mole weight: 412.52.
Cryptoporic acid D
It is produced by the strain of Cryptoporus volvatus. Synonyms: 7, 11, 24, 28-Tetraoxapentacyclo(28.4.0.0(5, 34).0(13, 18).0(17, 22))tetratriacontane-9, 26-diacetic acid, 8, 25-bis(methoxycarbonyl)-13, 17, 30, 34-tetramethyl-4, 21-bis(methylene)-10, 27-dioxo-, (1R-(1R*, 5S*, 8R*, 9S*, 13R*, 17S*, 18R*, 22S*, 25R*, 26S*, 30R*, 34S*))-. CAS No. 119979-95-2. Molecular formula: C44H64O14. Mole weight: 816.97.
Cryptoporic acid E
It is produced by the strain of Cryptoporus volvatus. Synonyms: (3S,4R)-3-((((1R,4aS,5S,8aR)-5-((((2R,3S)-3-(carboxymethyl)-1,4-dimethoxy-1,4-dioxobutan-2-yl)oxy)methyl)-1,4a-dimethyl-6-methylenedecahydronaphthalen-1-yl)methoxy)carbonyl)-4-(((1S,4aR,5R,8aS)-5-(hydroxymethyl)-5,8a-dimethyl-2-methylenedecahydronaphthalen-1-yl)methoxy)-5-methoxy-5-oxopentanoic acid. CAS No. 120001-10-7. Molecular formula: C45H68O15. Mole weight: 849.01.
Cryptosporiopsin
It is produced by the strain of Cryptosporiopsis sp. and Sporormia affinis. It has antibacterial activity to many kinds of basidiomycetes, algal fungi, ascomycetes and hemiplegia fungi that cause wood rot, and can inhibit spore germination of Phytophthora potatoes. It also has certain activity against gram-positive bacteria and negative bacteria. Synonyms: (+)-Cryptosporiopsin; 2-Cyclopentene-1-carboxylic acid, 5-dichloro-1-hydroxy-4-oxo-2-propenyl-, methyl ester, (E)-(1S,5S)-(+)-. CAS No. 25707-30-6. Molecular formula: C10H10Cl2O4. Mole weight: 265.09.
Cryptosporiopsin A
It is produced by the strain of Cryptosporiopsis sp. and Sporormia affinis. It has antibacterial activity to many kinds of basidiomycetes, algal fungi, ascomycetes and hemiplegia fungi that cause wood rot, and can inhibit spore germination of Phytophthora potatoes. It also has certain activity to gram-positive bacteria and negative bacteria. Synonyms: (3R,9E)-13-Chloro-4,5,7,8-tetrahydro-14-hydroxy-16-methoxy-3-methyl-1H-2-benzoxacyclotetradecin-1,6,11(3H,12H)-trione. CAS No. 1402990-52-6. Molecular formula: C19H21ClO6. Mole weight: 380.82.
Cuevaene A
It is produced by the strain of Streptomyces sp. HKI 0180. It has a moderate level of activity against gram-positive bacteria, Its MIC against Staphylococcus aureus and Bacillus subtilis is greater than 50 μg/mL. Synonyms: (2E,4Z,6E)-7-(8-hydroxy-1,2,3,4-tetrahydrodibenzo[b,d]furan-1-yl)-4-methoxy-6-methylhepta-2,4,6-trienoic acid. CAS No. 1246172-08-6. Molecular formula: C21H22O5. Mole weight: 354.40.
Cuevaene B
It is produced by the strain of Streptomyces sp. HKI 0180. It has a moderate level of activity against gram-positive bacteria, Its MIC against Staphylococcus aureus and Bacillus subtilis is greater than 50 μg/mL. CAS No. 274684-11-6. Molecular formula: C21H24O7. Mole weight: 388.41.
Culpin
It is produced by the strain of Preussia sp. It has weak antibacterial and antifungal activity. Synonyms: 2-(3-Methyl-2-butenyl)-5-(3-methyl-3-buten-1-ynyl)-1,4-benzenediol. Grades: ≥ 98%. CAS No. 125213-21-0. Molecular formula: C16H18O2. Mole weight: 242.31.
Curromycin A
It is produced by the strain of Streptomyces hygroscipicus 358AV2. It has antibacterial activity against gram-positive bacteria such as Bacillus subtilis. It can inhibit the replication of human immunodeficiency virus (HIV), inhibit mouse melanoma B16 and leukemia P388 cells. Synonyms: Triedimycin A; 4,6,8-Decatrienamide, 3-hydroxy-N-(6-hydroxy-9-(8-hydroxy-1-(methoxymethyl)-5,7-dimethyl-3,6-dioxo-2-oxa-5-azaspiro(3.4)oct-8-yl)-9-methoxy-7-methyl-2,4-nonadienyl-2,2,4-trimethyl-10-(2-methyl-5-oxazolyl)-. CAS No. 97412-76-5. Molecular formula: C38H55N3O10. Mole weight: 713.87.
Curromycin B
It is produced by the strain of Streptomyces hygroscipicus 358AV2. It has antibacterial activity against gram-positive bacteria such as Bacillus subtilis. It can inhibit the replication of human immunodeficiency virus (HIV), inhibit mouse melanoma B16 and leukemia P388 cells. Synonyms: Triedimycin B; 4,6,8-Decatrienamide, 3-hydroxy-N-(6-hydroxy-9-(8-hydroxy-1,5,7-trimethyl-3,6-dioxo-2-oxa-5-azaspiro(3.4)oct-8-yl)-9-methoxy-7-methyl-2,4-nonadienyl-2,2,4-trimethyl-10-(2-methyl-5-oxazolyl)-; 30-Demethoxycurromycin A. CAS No. 97412-77-6. Molecular formula: C37H53N3O9. Mole weight: 683.84.
Curtisian B
It is produced by the strain of Paxillus curtisii. It is a free radical scavenger. It inhibits lipid peroxidation with IC50 of 0.17 μg/mL. Synonyms: 3',5',6'-tris(acetyloxy)-4,4''-dihydroxy-1,1':4',1''-terphenyl-2'-yl 3-phenylpropanoate; 2',3',6'-Triacetoxy-5'-(phenethylcarbonyloxy)-1,1':4',1''-terbenzene-4,4''-diol. Molecular formula: C33H28O10. Mole weight: 584.57.
Curtisian C
It is produced by the strain of Paxillus curtisii. It is a free radical scavenger. It inhibits lipid peroxidation with IC50 of 0.24 μg/mL. Synonyms: [4-acetyloxy-2,5-bis(3-acetyloxybutanoyloxy)-3,6-bis(4-hydroxyphenyl)phenyl] 3-hydroxybutanoate. Molecular formula: C36H38O15. Mole weight: 710.68.
Curtisian D
It is produced by the strain of Paxillus curtisii. It is a free radical scavenger. It inhibits lipid peroxidation with IC50 of 0.24 μg/mL. Synonyms: 5',6'-bis(acetyloxy)-4,4''-dihydroxy-3'-[(3-phenylpropanoyl)oxy]-1,1':4',1''-terphenyl-2'-yl 3-hydroxybutanoate; 5',6'-Diacetoxy-2'-(3-phenylpropanoyloxy)-3'-(3-hydroxybutanoyloxy)-1,1':4',1''-terbenzene-4,4''-diol. Molecular formula: C35H32O11. Mole weight: 628.62.
Curvularin
It is produced by the strain of Curvularia sp., Penicillum gilmanii and Pen. citroviride. It strongly inhibits cell division and is a toxin harmful to plants. Synonyms: S-Curvularin; NSC 166071; 11,13-Dihydroxy-4-methyl-4,5,6,7,8,9-hexahydro-2H-3-benzoxacyclododecine-2,10(1H)-dione; 2H-3-Benzoxacyclododecin-2,4,5,6,7,8,9-hexahydro-11,13-dihydroxy-4-methyl-, (S)-. Grades: >99% by HPLC. CAS No. 10140-70-2. Molecular formula: C16H20O5. Mole weight: 292.33.
Curvularol
It is produced by the strain of Curvularia sp. RK97-F166. It has weak anti-fungal activity and no anti-bacterial effect. Curvularol of 150 ng/mL inhibits the cell cycle progression of NRK in normal rats at G1 stage. Curvularol of 100 ng/mL can restore the morphology of SRC TS-deformed NRK cells. Like Cycloheximide, it inhibits protein synthesis. Synonyms: (2S,4S,5S,5aR,9aS,10S)-5,5a,8-trimethyl-5a,6,7,9a-tetrahydro-5H-spiro[2,5-methano[1]benzoxepine-4,2'-oxirane]-2,10(3H)-diol. CAS No. 339293-67-3. Molecular formula: C15H22O4. Mole weight: 266.33.
Curvulic acid
It is produced by the strain of Curvularia siddiqui, Penicillum janthynellum C-268. It has weak activity against gram-positive and negative bacteria. Para-aminobenzoic acid can antagonize its action. Synonyms: 2-Acetyl-3,5-dihydroxy-4-methoxy-phenylessigsaeure; 2-Acetyl-3,5-dihydroxy-4-methoxybenzeneacetic acid. CAS No. 652-55-1. Molecular formula: C11H12O6. Mole weight: 240.21.
Curvulinic acid
Curvulinic acid is a phytotoxin isolated from C. siddiqui. Grades: >95% by HPLC. CAS No. 19053-94-2. Molecular formula: C10H10O5. Mole weight: 210.18.
CV-1
CV-1 is an antibiotic produced by Streptomyces sp. CO-1. It has anti-Escherichia coli activity in combination with spiramycin, and its mechanism is to inhibit lipopolysaccharide synthesis. Synonyms: 1,2-Diamino-1,2-N,N'-carbonyl-1,2-dideoxyglucose hydrate. CAS No. 108351-34-4. Molecular formula: C7H14N2O6. Mole weight: 222.20.
Cyathin A3
It is produced by the strain of Cyathus helenae, C. africanus. It has weak activity against gram-positive bacteria, negative bacteria, actinomycetes and dermatophytes, and has anti-ischemia effect (improving cerebral ischemia in rat model). CAS No. 38598-35-5. Molecular formula: C20H30O3. Mole weight: 318.45.
Cyathin A4
It is produced by the strain of Cyathus helenae, C. africanus. It has weak activity against gram-positive bacteria, negative bacteria, actinomycetes and dermatophytes, and has anti-ischemia effect (improving cerebral ischemia in rat model). Molecular formula: C20H30O4. Mole weight: 334.45.
Cyclacidin
It is produced by the strain of Streptomyces capoamus 4670-IA 37. It has anti-individual gram-positive bacteria (subtilis, Gambosia occidentalis) activity, and has inhibitory effect on sarcoma 180 and so on. Synonyms: Bisanhydrorutilantinone; pi-Pyrromycinone; Bisanhydropyrromycinone; eta-Pyrromycinone; 1-Naphthacenecarboxylic acid, 6,11-dihydro-6,11-dioxo-2-ethyl-5,7,9-trihydroxy-, methyl ester; Methyl 6,11-dihydro-6,11-dioxo-2-ethyl-5,7,9-trihydroxy-1-naphthacenecarboxylate; ciclacidine. CAS No. 749-18-8. Molecular formula: C22H16O7. Mole weight: 392.36.
Cyclipostin A
It is produced by the strain of Streptomyces sp. DSM 13381. It is a hormone-sensitive lipase (HSL) inhibitor with a MIC of 20 nmol/L against HSL in rats. Molecular formula: C23H41O7P. Mole weight: 460.54.
Cyclipostin P
It is produced by the strain of Streptomyces sp. DSM 13381. It is a hormone-sensitive lipase (HSL) inhibitor with a MIC of 30 nmol/L against HSL in rats. Synonyms: (1beta)-4beta-(Hexadecyloxy)-6-methyl-8-oxo-3,5,9-trioxa-4-phosphabicyclo[5.3.0]deca-6-ene 4-oxide; (6S)-6alpha-(Hexadecyloxy)-8-methyl-3,3abeta-dihydro-1H,4H,6H-2,5,7-trioxa-6-phosphaazulene-1-one 6-oxide. Molecular formula: C23H41O6P. Mole weight: 444.54.
Cyclipostin P2
It is produced by the strain of Streptomyces sp. DSM 13381. It is a hormone-sensitive lipase (HSL) inhibitor with a MIC of 40 nmol/L against HSL in rats. Molecular formula: C23H41O6P. Mole weight: 444.54.
Cyclipostin S
It is produced by the strain of Streptomyces sp. DSM 13381. It is a hormone-sensitive lipase (HSL) inhibitor with a MIC of 20 nmol/L against HSL in rats. Molecular formula: C24H43O6P. Mole weight: 458.57.
It is produced by the strain of Penicillium islandicum. It can accelerate the degradation of glycogen and make the Liver glycogen particles disappear. Synonyms: Chloropeptide; Cyclic(L-3-phenyl-beta-alanyl-L-seryl-(3S-cis)-3,4-dichloro-L-prolyl-L-alpha-aminobutyryl-L-seryl). Grades: ≥ 98%. CAS No. 12663-46-6. Molecular formula: C24H31Cl2N5O7. Mole weight: 572.44.
It is a diketopiperazine formed by the fusion of δ-alanine and valine and is a secondary metabolite of fungi and bacteria. It can activate N-acylhomoserine lactones (AHLs) and can also activate or antagonize other LuxR-based quorum-sensing systems. Synonyms: 3-Methylene-6S-(1-methylethyl)-2,5-piperazinedione; 2,5-Piperazinedione, 3-methylene-6-(1-methylethyl)-, (S)-; Cyclo(Δ-Ala-L-Val). Grades: >98% by HPLC. CAS No. 25516-00-1. Molecular formula: C8H12N2O2. Mole weight: 168.19.
Cyclo (D-Pro-L-Val)
It is produced by the strain of Aspergillus sp. F70609. It can inhibit β-glucoside enzyme activity with IC50 of 75 μg/mL. It has no or only weak inhibitory effect on other glycosidases. Synonyms: (3S,8aR)-3-isopropylhexahydropyrrolo[1,2-a]pyrazine-1,4-dione; Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro-3-(1-methylethyl)-, (3S,8aR)-. CAS No. 156617-55-9. Molecular formula: C10H16N2O2. Mole weight: 196.25.
Cycloechinulin
An unusual diketopiperazine isolated from aspergillus ochraceus. It exhibits insecticidal activity against the lepidopteran crop pest, helicoverpa zea. It is used as a secondary metabolite standard for polyphasic taxonomy in aspergillus. Synonyms: (3S)-2, 3, 8, 9-Tetrahydro-11-methoxy-3, 8, 8-trimethylpyrazino[1', 2':1, 2]azocino[5, 4-b]indole-1, 4-dione; (S)-2,3,8,9-Tetrahydro-11-methoxy-3,8,8-trimethyl-pyrazino[1',2':1,2]azocino[5,4-b]indole-1,4-dione. Grades: >99% by HPLC. CAS No. 143086-29-7. Molecular formula: C20H21N3O3. Mole weight: 351.40.
Cycloepoxydon
It is produced by the strain of Duteromycete 45-93. It can inhibit TPA induced expression of k gene binding nuclear factor (NF-KB) and activator protein-1 (APT-1) mediated secreted alkaline phosphatase (SEAP), with IC50 of 4.2-9.4 mol/L and 4.2-9.4 mol/L, respectively. Molecular formula: C12H16O5. Mole weight: 240.25.
It is produced by the strain of Aspergillus panamensis. It has anti-bacterial and fungal activity, but its antibacterial and fungal activity is lower than polymyxin A. It inhibits airy ascites carcinoma with MIC of 10 μg/mL (Gregatin A is 2 μg/mL). Synonyms: 4H-Furo(2,3-b)pyran-3,4(2H)-dione, 2-(1,3-hexadienyl)-5,6-dihydro-2,6-dimethyl-. CAS No. 120167-25-1. Molecular formula: C15H18O4. Mole weight: 262.30.
Cycloheptamycin
It is produced by the strain of Streptomyces sp. MZ 1158. It has anti-gram-positive bacterial and mycobacterium activity. CAS No. 30270-78-1. Molecular formula: C48H68N8O12. Mole weight: 949.10.