BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Clavariopsin B | It is produced by the strain of Clavariopsis aquatica AJ117363. Clavariopsin B has anti-candida albicans, Aspergillus fumigata and Aspergillus Niger activity, and has little effect on bacteria. Synonyms: 2-{(4S, 7S, 10S, 13S, 16S, 22S, 25S, 28R)-3, 6, 9, 12, 15, 18, 21, 24, 30-Nonaaza-13, 16-bis((1S)-1-methylpropyl)-25-[(4-methoxyphenyl)methyl]-9, 12, 15, 21-tetramethyl-27-oxa-2, 5, 8, 11, 14, 17, 20, 23, 26, 29-decaoxo-4, 7, 22, 28-tetrakis(methylethyl)bicyclo[28. 4. 0]tetratriacont-10-yl}acetic acid. Molecular formula: C58H93N9O14. Mole weight: 1140.41. |  |
| Clavicoronic acid | Clavicoronic acid is produced by the strain of Clavicorona pyxidata. It can inhibit the reverse transcriptase activity of myeloblastocytosis virus (AMV) and Moloney mouse leukemia virus (MMuLV). Synonyms: (6-Formyl-2,2,4-trimethyl-2,3,3a,7a-tetrahydro-1H-inden-5-yl)(oxo)acetic acid; 1H-Indene-5-acetic acid, 6-formyl-2,3,3a,7a-tetrahydro-2,2,4-trimethyl-alpha-oxo-, (3aS-cis)-. CAS No. 139748-98-4. Molecular formula: C15H18O4. Mole weight: 262.30. | |
| Clavilactone A | Clavilactone A is produced by the strain of Clitocybe clavipes. It can inhibit the germination of seeds. Molecular formula: C15H16O5. Mole weight: 276.28. | |
| Clavilactone C | Clavilactone C is produced by the strain of Clitocybe clavipes. It can inhibit the germination of seeds. Molecular formula: C16H16O6. Mole weight: 304.29. | |
| Clavulanate Lithium | A beta-lactamase inhibitor. It can irreversibly inactivate beta-lactamase enzymes of beta-lactam resistant microbes preventing them from breaking down beta-lactam antibiotics. Synonyms: (2R,5R,Z)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylate Lithium; Clavulanic acid, lithium salt. Grades: ≥98%. CAS No. 61177-44-4. Molecular formula: C8H8LiNO5. Mole weight: 205.09. | |
| Clazamycin A | It is produced by the strain of Streptomyces No. NF990-BF4. Clazamycin A has weak activity against gram-positive bacteria, gram-negative bacteria and L1210 cell. Synonyms: (2S-trans)-2-Chloro-5-inino-2,3-dihydro-1H-pyrrolizin-7alpha(5H)-ol. CAS No. 71806-55-8. Molecular formula: C7H9ClN2O. Mole weight: 172.61. | |
| Clecarmycin A1 | It is produced by the strain of Streptomyces sp. DO-114. Clecarmycin A1 has anti-gram-positive bacteria activity with MIC 0.04-0.33μg/mL and has stronger anti-gram-negative bacteria and candida albicans than C. Clecarmycin A1 also showed strong cytotoxicity, with IC50 of 6.58 mg/mL against HeLa S3 cells, which was 10-20 times stronger than adriamycin. Molecular formula: C29H24O11. Mole weight: 548.49. | |
| Clecarmycin C | It is produced by the strain of Streptomyces sp. DO-114. Clecarmycin C has anti-gram-positive bacteria activity with MIC 0.04-0.33μg/mL. It also showed strong cytotoxicity, with IC50 of 11.5 mg/mL against HeLa S3 cells, which was 10-20 times stronger than adriamycin. CAS No. 136427-31-1. Molecular formula: C29H26O11. Mole weight: 550.51. | |
| Cleomycin A2 | It is produced by the strain of Streptomyces verticillus NK-68-144. It has anti-mycobacterial and HeLa cell activity. Synonyms: 3S, S-Dimethylmercaptopropyl aminocleomycin; Bleomycinamide, 16-de(1-hydroxyethyl)-N1-(3-(dimethylsulfonio)propyl)-16-(1-hydroxycyclopropyl)-. CAS No. 754137-61-6. Molecular formula: C56H84N17O21S3. Mole weight: 1427.56. | |
| Cleomycin B2 | It is produced by the strain of Streptomyces vericillus NK68-144. Cleomycin B2 has the same structure as the corresponding bleomycin. Synonyms: Bleomycinamide, N(1)-(4-((aminoiminomethyl)amino)butyl)-16-de(1-hydroxyethyl)-16-(1-hydroxycyclopropyl)-, (16S)-. CAS No. 76741-88-3. Molecular formula: C56H84N20O21S2. Mole weight: 1437.51. | |
| Clerocidin | Clerocidin is produced by the strain of Oidiodendron truncatum HL-972. It has anti-gram-positive and negative bacteria activity and inhibits mouse P-388 leukemia. Synonyms: Antibiotic PR-1350. CAS No. 87501-14-2. Molecular formula: C40H56O10. Mole weight: 696.84. | |
| Clethramycin | It is produced by the strain of Streptomyces hygroscopicus TPA0623. Clethramycin has activities against candida, cryptococcus neoforme and aspergillus fumigatus with MIC of 0.5-8 μg/mL. And it also inhibits the growth of Pollen tubes. Synonyms: CHEBI:65643. Molecular formula: C63H99N3O18S. Mole weight: 1218.53. | |
| Clindamycin hydrochloride monohydrate | Clindamycin is an antibiotic in the lincosamide class which binds the bacterial 50S ribosomal subunit and interferes with protein synthesis. CAS No. 58207-19-5. Molecular formula: C18H36Cl2N2O6S. Mole weight: 479.46. | |
| Clitidine | Clitidine is produced by the strain of Clitocybe acromelalga. hypertoxic substance. Synonyms: Chrytidine; 4-imino-1-beta-ribofuranosyl-1,4-dihydro-3-pyridinecarboxylic acid. CAS No. 63592-84-7. Molecular formula: C11H14N2O6. Mole weight: 270.24. | |
| Cloxacillin Sodium Monohydrate | Cloxacillin Sodium Monohydrate is a sodium salt of cloxacillin that is a penicillinase-resistant, acid resistant, semi-synthetic penicillin. Uses: Anti-bacterial agents. Synonyms: Cloxapen. Grades: >98%. CAS No. 7081-44-9. Molecular formula: C19H19ClN3NaO6S. Mole weight: 475.88. | |
| Cochleamycin A | It is produced by the strain of Streptomyces sp. DT136. Cochleamycin A showed strong inhibitory activity against tumor cells, with IC50 (μg/mL) of P388, HL60, K562, COL0205 and HT29 cells of 1.6, 14.0, 6.2, 16.5 and 19.1, respectively. It also has anti-gram-positive bacteria activity. Molecular formula: C21H26O6. Mole weight: 374.43. | |
| Cochleamycin A2 | It is produced by the strain of Streptomyces sp. DT136. Cochleamycin A2 has the activity of inhibiting tumor cells and anti-gram-positive bacteria. Molecular formula: C23H30O6. Mole weight: 402.48. | |
| Cochleamycin B | It is produced by the strain of Streptomyces sp. DT136. Cochleamycin B has the activity of inhibiting tumor cells. Molecular formula: C21H26O5. Mole weight: 358.43. | |
| Cochleamycin B2 | It is produced by the strain of Streptomyces sp. DT136. Cochleamycin B has the activity of inhibiting tumor cells. Molecular formula: C23H30O5. Mole weight: 386.48. | |
| Cochlioquinone A | It is produced by the strain of Bipolaris zeicila. Cochlioquinone A inhibited DGAT with IC50 of 5.6 μg/mL. Synonyms: Coclioquinone A; Pyrano[3,2-a]xanthene-8,11-dione,9-[(1S,2R,3S)-2-(acetyloxy)-1,3-dimethylpentyl]-1,2,3,4a,5,6,6a,12,12a,12b-decahydro-12-hydroxy-3-(1-hydroxy-1-methylethyl)-6a,12b-dimethyl-,(3R,4aR,6aR,12S,12aS,12bR)-; Luteoleersin. Grades: >99% by HPLC. CAS No. 32450-25-2. Molecular formula: C30H44O8. Mole weight: 532.66. | |
| Cochlioquinone A1 | It is produced by the strain of Bipolaris zeicila. Cochlioquinone A1 inhibited DGAT with IC50 of 6.3 μg/mL. Molecular formula: C33H50O9. Mole weight: 590.74. | |
| Cochlioquinone B | It is the minor component of a bioactive pigment isolated from Bipolaris cynodontis and Cochliobolus miyabeanus. It is an NADH-ubiquinone reductase inhibitor. It is also a phytotoxic agent inhibiting root growth. It is closely related to cochlioquinone A which inhibits diacylglycerol acyltransferase and exhibits anti-angiogenic and nematocidal activity. It is an antagonist of the human chemokine receptor, CCR5, in HIV-1. Synonyms: 20-De(acetyloxy)-11-deoxy-20-oxo-cochlioquinone A; 9-(1, 3-Dimethyl-2-oxopentyl)-1, 2, 3, 4aα, 5, 6, 6a, 12, 12aα, 12b-decahydro-3β-(1-hydroxy-1-methylethyl)-6aβ, 12bβ-dimethyl-pyrano[3, 2-a]xanthene-8, 11-dione Stereoisomer; (3R,4aR,6aR,12aR,12bR)-9-[(1S,3S)-1,3-Dimethyl-2-oxopentyl]-1,2,3,4a,5,6,6a,12,12a,12b-decahydro-3-(1-hydroxy-1-methylethyl)-6a,12b-dimethylpyrano[3,2-a]xanthene-8,11-dione. Grades: >99% by HPLC. CAS No. 32450-26-3. Molecular formula: C28H40O6. Mole weight: 472.61. | |
| Coformycin | Coformycin is a potent inhibitor of adenosine deaminase (ADA) from Streptomyces species. Coformycin possesses anti-tumor and anti-bacterial activity. Synonyms: (R)-3,4,7,8-Tetrahydro-3-beta-D-ribofuranosylimidazo(4,5-d)(1,3)diazepin-8-ol; (8R)-3-beta-D-ribofuranosyl-3,6,7,8-tetrahydroimidazo[4,5-d][1,3]diazepin-8-ol. Grades: 98%. CAS No. 11033-22-0. Molecular formula: C11H16N4O5. Mole weight: 284.27. | |
| Colabomycin A | It is produced by the strain of Streptomyces griseoflavus. It has anti-gram-positive bacterial activity similar to Manumycin, and has the activity of inhibiting leukemic cell L1210. IC50 is 3.4 μg/mL. Synonyms: (2E,4E,6E,8E)-N-[(1beta,6beta)-5alpha-Hydroxy-5-[(1E,3E,5E,7E)-9-[(2-hydroxy-5-oxo-1-cyclopentene-1-yl)amino]-9-oxo-1,3,5,7-nonatetrenyl]-2-oxo-7-oxabicyclo[4.1.0]hepta-3-ene-3-yl]-2,4,6,8-decatetrenamide. CAS No. 117778-57-1. Molecular formula: C30H30N2O7. Mole weight: 530.57. | |
| Colistin | It is produced by the strain of Bacillus polymyxa var. colistinus and Bac. colistinum Koyama 70-B. It has good anti-gram-negative bacterial activity, but has poor effect on Pseudomonas aeruginosa and Proteus aeruginosa. Colistin, also known as polymyxin E, is an antibiotic medication used as a last-resort treatment for multidrug-resistant Gram negative infections including pneumonia. Synonyms: Polymyxin E; Colobreathe; Promixin; Colimycin M; Belcomycin; Colymycin; Torazin; N-[(1S)-3-amino-1-[[(1S,2R)-1-[[(1S)-3-amino-1-[[(3S,6S,9S,12S,15R,18S,21S)-6,9,18-tris(2-aminoethyl)-3-[(1R)-1-hydroxyethyl]-12,15-diisobutyl-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptazacyclotricos-21-yl]carbamoyl]propyl]carbamoyl]-2-hydroxy-propyl]carbamoyl]propyl]-5-methyl-heptanamide. Grades: >95% by HPLC. CAS No. 1066-17-7. Molecular formula: C52H98N16O13. Mole weight: 1155.43. | |
| Colistin A | Colistin A is an antibiotic produced by certain strains of the bacteria Paenibacillus polymyxa. Colistin is a polymyxin antibiotic and can be used to combat infections caused by problematic gram-negative bacteria. Synonyms: Polymixin E1. Grades: ≥ 95%. CAS No. 7722-44-3. Molecular formula: C53H100N16O13. Mole weight: 1169.48. | |
| Colistin B | It is produced by the strain of Bacillus polymyxa var. colistinus and Bac. colistinum Koyama 70-B. It has good anti-gram-negative bacterial activity, but has poor effect on Pseudomonas aeruginosa and Proteus aeruginosa. Colistin B is used as an antibiotic in the treatment of infectious diseases resulting from multi-drug resistant (MDR) gram-negative bacteria. Synonyms: Polymyxin E2; Colistin b; 4,10-anhydro[N-(6-methylheptanoyl)-L-2,4-diaminobutanoyl-L-threonyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-D-leucyl-L-leucyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-L-threonine]. Grades: ≥ 95%. CAS No. 7239-48-7. Molecular formula: C52H98N16O13. Mole weight: 1155.43. | |
| Colistin sodium methanesulfonate | A unique sparingly soluble cyclic polypeptide antibiotic known as a polymyxin. It has a bactericidal effect on bacteria by targeting the cell membrane and modifying its permeability. CAS No. 8068-28-8. Molecular formula: C58H105N16Na5O28S5. Mole weight: 1749.8. | |
| Colistin sulfate | Colistin sulfate is a polypeptide antibiotic containing greater than 30 components, with colistin A and colistin B as the major components. It inhibits gram-negative bacteria by binding to lipopolysaccharides and phospholipids in the outer cell membrane of gram-negative bacteria. Colistin was originally isolated from B. polymyxa. Synonyms: Polymyxin E Complex; Colistin sulfate salt (2:5); Belcomycine; Colomycin. Grades: ≥95%. CAS No. 1264-72-8. Molecular formula: Colistin A: C53H100N16O13; Colistin B: C52H98N16O13. Mole weight: Colistin A: 1169.46; Colistin B: 1155.43. | |
| Collinemycin | It is produced by the strain of Actinosporaangium sp. C236145. It has anti-gram-positive bacteria and tumor activity. Synonyms: 10-epi-Musettamycin; Musettamycin; 1-Naphthacenecarboxylic acid,1,2,3,4,6,11-hexahydro-6,11-dioxo-2-ethyl-2,5,7,10-tetrahydroxy-4-((2,3,6-trideoxy-4-O-(2,6-dideoxy-alpha-L-lyxo-hexopyranosyl)-3-(dimethylamino)-alpha-L-lyxo-hexopyranosyl)oxy)-, methyl ester, (1S-(1-alpha,2-alpha,4-alpha))-; NSC-304416. CAS No. 72598-49-3. Molecular formula: C36H45NO14. Mole weight: 715.74. | |
| Collinomycin | It is produced by the strain of Streptomyces collinus. It has anti-gram-positive bacterial activity and inhibits human immunodeficiency virus-1 (HIV-1) reverse transcriptase activity. Synonyms: alpha-Rubromycin; Rubromycin; Tuoromycin; Methyl 7,8-dihydroxy-6-[2-(8-hydroxy-5,7-dimethoxy-4,9-dioxo-4,9-dihydronaphtho[2,3-b]furan-2-yl)ethyl]-1-oxo-1H-2-benzopyran-3-carboxylate. CAS No. 27267-69-2. Molecular formula: C27H20O12. Mole weight: 536.44. | |
| Collinone | It is produced by the strain of Streptomuces coelicolor CH999. It has anti-gram-positive bacterial activity including methicillin-resistant staphylococcus aureus (MRSA) and vancomycin resistant enterococcus (VRE). MIC is 16-32 μg/mL. It has no effect on gram-negative bacteria, fungi and viruses. It is toxic to HeLa, Vero, MT-4 and other tumor cells. CAS No. 343315-22-0. Molecular formula: C27H18O12. Mole weight: 534.42. | |
| Collismycin A | It is produced by the strain of Streptomyces sp. MQ22. It has the inhibitory effect of dexamethasone-glucocorticoid receptor. IC50 is 1.5 X 10-5 mol/L (rat liver cytosol). It has the anti-tumor cell activity, inhibits rat leukemia cell L1210 with IC50 of 0.08 μg/mL. Synonyms: (E)-4-Methoxy-5-(methylthio)-[2,2'-bipyridine]-6-carbaldehyde oxime; (2E)-4-methoxy-3-methylsulfanyl-2-(nitrosomethylidene)-6-pyridin-2-yl-1H-pyridine. Grades: ≥ 95%. CAS No. 158792-24-6. Molecular formula: C13H13N3O2S. Mole weight: 275.33. | |
| Collismycin B | It is produced by the strain of Streptomyces sp. MQ22. It has the inhibitory effect of dexamethasone-glucocorticoid receptor. IC50 is 1.0 X 10-5 mol/L (rat liver cytosol). It has the anti-tumor cell activity, inhibits rat leukemia cell L1210 with IC50 of 0.12 μg/mL. Synonyms: (2Z)-4-methoxy-3-methylsulfanyl-2-(nitrosomethylidene)-6-pyridin-2-yl-1H-pyridine; 4-methoxy-3-methylsulfanyl-2-(nitrosomethylene)-6-(2-pyridyl)-1H-pyridine. CAS No. 158792-25-7. Molecular formula: C13H13N3O2S. Mole weight: 275.33. | |
| Combimicin A2 | It is produced by the strain of Micromonospora sp. K-6993, K-6993-Y-41, NRRL 2958-N-6. It's a kanamycin homolog. CAS No. 72300-83-5. Molecular formula: C20H40N4O9. Mole weight: 480.55. | |
| Combimicin B1 | It is produced by the strain of Micromonospora sp. K-6993, K-6993-Y-41, NRRL 2958-N-6. It's a kanamycin homolog. CAS No. 72265-93-1. Molecular formula: C21H43N5O8. Mole weight: 493.59. | |
| Combimicin B2 | It is produced by the strain of Micromonospora sp. K-6993, K-6993-Y-41, NRRL 2958-N-6. It's a kanamycin homolog. Synonyms: Combimicin B(sub 2); D-Streptamine, O-3-deoxy-4-C-methyl-3-(methylamino)-alpha-D-galactopyranosyl-(1-6)-O-(2,6-diamino-2,3,4,6-tetradeoxy-alpha-D-erythro-hexopyranosyl-(1-4))-2-deoxy-; 4,6-Diamino-3-{[3-deoxy-4-C-methyl-3-(methylamino)hexopyranosyl]oxy}-2-hydroxycyclohexyl 2,6-diamino-2,3,4,6-tetradeoxyhexopyranoside. CAS No. 72265-90-8. Molecular formula: C20H41N5O8. Mole weight: 479.57. | |
| Conagenin | It is produced by the strain of Sreptomyces roseosporus M1696-AF3. It is a low molecular immune modulator. Synonyms: (S)-2-((2R,3S,4R)-2,4-dihydroxy-3-methylpentanamido)-3-hydroxy-2-methylpropanoic acid; N-(3,5-Dideoxy-3-methyl-D-xylonoyl)-2-methyl-L-serine; Conagenine. CAS No. 134381-30-9. Molecular formula: C10H19NO6. Mole weight: 249.26. | |
| Concanamycin A | It is produced by the strain of Streptomyces diastatochromogenes. It has antifungal, antiviral, immunosuppressive, cytotoxic and other activities, and is a specific inhibitor of V-type ATPase (Ki=0.02 nmol/L), which is an important tool for biochemical research. Synonyms: Folimycin; concanamycin a; Antibiotic X 4357 B; Antibiotic S-45A; X 4357B; (3Z, 5E, 7R, 8R, 9S, 10S, 11R, 13E, 15E, 17S, 18R)-18-[(1S, 2R, 3S)-3-[(2R, 4R, 5S, 6R)-4-[[4-O-(Aminocarbonyl)-2, 6-dideoxy-β-D-arabino-hexopyranosyl]oxy]tetrahydro-2-hydroxy-5-methyl-6-(1E)-1-propen-1-yl-2H-pyran-2-yl]-2-hydroxy-1-methylbutyl]-9-ethyl-8, 10-dihydroxy-3, 17-dimethoxy-5, 7, 11, 13-tetramethyloxacyclooctadeca-3, 5, 13, 15-tetraen-2-one. Grades: >99% by HPLC. CAS No. 80890-47-7. Molecular formula: C46H75NO14. Mole weight: 866.09. | |
| Concanamycin B | It is produced by the strain of Streptomyces diastatochromogenes. It has antifungal, antiviral, immunosuppressive, cytotoxic and other activities, and is a specific inhibitor of V-type ATPase, which is an important tool for biochemical research. Synonyms: (3Z, 5E, 7R, 8R, 9S, 10S, 11R, 13E, 15E, 17S, 18R)-18-[(1S, 2R, 3S)-3-[(2R, 4R, 5S, 6R)-4-[[4-O-(Aminocarbonyl)-2, 6-dideoxy-β-D-arabino-hexopyranosyl]oxy]tetrahydro-2-hydroxy-5-methyl-6-(1E)-1-propenyl-2H-pyran-2-yl]-2-hydroxy-1-methylbutyl]-8, 10-dihydroxy-3, 17-dimethoxy-5, 7, 9, 11, 13-pentamethyloxacyclooctadeca-3, 5, 13, 15-tetraen-2-one; MCH 210; 8-Deethyl-8-methylconcanamycin A. Grades: >95% by HPLC. CAS No. 81552-33-2. Molecular formula: C45H73NO14. Mole weight: 852.06. | |
| Concanamycin C | It is produced by the strain of Streptomyces diastatochromogenes. It has antifungal, antiviral, immunosuppressive, cytotoxic and other activities, and is a specific inhibitor of V-type ATPase, which is an important tool for biochemical research. Synonyms: (3Z, 5E, 7R, 8R, 9S, 10S, 11R, 13E, 15E, 17S, 18R)-18-[(1S, 2R, 3S)-3-[(2R, 4R, 5S, 6R)-4-[(2, 6-Dideoxy-β-D-arabino-hexopyranosyl)oxy]tetrahydro-2-hydroxy-5-methyl-6-(1E)-1-propen-1-yl-2H-pyran-2-yl]-2-hydroxy-1-methylbutyl]-9-ethyl-8, 10-dihydroxy-3, 17-dimethoxy-5, 7, 11, 13-tetramethyloxacyclooctadeca-3, 5, 13, 15-tetraen-2-one; 4'-O-de(aminocarbonyl)-Concanamycin A. Grades: ≥98%. CAS No. 81552-34-3. Molecular formula: C45H74O13. Mole weight: 823.06. | |
| Concanamycin D | It is produced by the strain of Streptomyces diastatochromogenes. It has antifungal, antiviral, immunosuppressive, cytotoxic and other activities, and is a specific inhibitor of V-type ATPase, which is an important tool for biochemical research. Synonyms: (3E,5Z,13Z,15Z)-18-[4-[4-[(2S,4R,5S,6R)-4,5-dihydroxy-6-methyloxan-2-yl]oxy-2-hydroxy-5-methyl-6-[(E)-prop-1-enyl]oxan-2-yl]-3-hydroxypentan-2-yl]-8,10-dihydroxy-3,17-dimethoxy-5,7,9,11,13-pentamethyl-1-oxacyclooctadeca-3,5,13,15-tetraen-2-one; 4'-O-de(aminocarbonyl)-8-deethyl-8-methyl-Concanamycin A. CAS No. 144450-34-0. Molecular formula: C44H72O13. Mole weight: 809.03. | |
| Concanamycin E | It is produced by the strain of Streptomyces diastatochromogenes. It has antifungal, antiviral, immunosuppressive, cytotoxic and other activities, and is a specific inhibitor of V-type ATPase, which is an important tool for biochemical research. Synonyms: Concanamycin A, 8-deethyl-; [6-[2-[4-[(4E,6E,14E,16Z)-10,12-dihydroxy-3,17-dimethoxy-7,9,13,15-tetramethyl-18-oxo-1-oxacyclooctadeca-4,6,14,16-tetraen-2-yl]-3-hydroxypentan-2-yl]-2-hydroxy-5-methyl-6-[(E)-prop-1-enyl]oxan-4-yl]oxy-4-hydroxy-2-methyloxan-3-yl] carbamate. CAS No. 144450-35-1. Molecular formula: C44H71NO14. Mole weight: 838.03. | |
| Concanamycin F | It is produced by the strain of Streptomyces diastatochromogenes. It has antifungal, antiviral, immunosuppressive, cytotoxic and other activities, and is a specific inhibitor of V-type ATPase, which is an important tool for biochemical research. Synonyms: Concanamycin A, 23-O-de(4-O-(aminocarbonyl)-2,6-dideoxy-beta-D-arabino-hexopyranosyl)-; concanolide A. CAS No. 144539-92-4. Molecular formula: C39H64O10. Mole weight: 692.92. | |
| Concanamycin G | It is produced by the strain of Streptomyces diastatochromogenes. It has antifungal, antiviral, immunosuppressive, cytotoxic and other activities, and is a specific inhibitor of V-type ATPase, which is an important tool for biochemical research. CAS No. 144730-82-5. Molecular formula: C38H60O9. Mole weight: 660.88. | |
| Conglobatin | Conglobatin is produced by the strain of Streptomyces conglobatus. It has a unusual, dimeric, macrolide dilactone structure with pendant oxazole groups. It exhibits an IC50 of 0.63 μg/mL in a NFAT-dependant transcription assay. It has no antifungal, bacterial, protozoan and tumor activity. Synonyms: (-)-Conglobatin; Conglobatin A; FW-04-806. Grades: >98% by HPLC. CAS No. 72263-05-9. Molecular formula: C28H38N2O6. Mole weight: 498.61. | |
| Coniosetin | It is produced by the strain of Coniochaeta ellipsoidea DSM 13856. It has activity against gram-positive bacteria, including clinical separation of multidrug resistant staphylococcus aureus and resistant to erythromycin streptococcus pneumoniae (MIC is 0.3-0.6 μg/mL), S. pyogenes, dung enterococcus and excrement enterococcus (MIC is 1.2-2.5 μg/mL). It has certain effect on yeast such as Candida albicans (MIC is 3.1 μg/mL). It has weak activity against gram-negative bacteria and other fungi. Synonyms: (5S)-5-[(S)-1-Hydroxyethyl]-3-[[1,2,4abeta,5,6,7,8,8aalpha-octahydro-1beta,3,6alpha-trimethyl-2alpha-[(1E,3E)-1,3-pentadienyl]naphthalene-1-yl]hydroxymethylene]pyrrolidine-2,4-dione. Molecular formula: C25H35NO4. Mole weight: 413.55. | |
| Conocandin | It is produced by the strain of Hormococcus conorium. It has strong antifungal activity. Synonyms: 2-Methylidene-10-methyl-trans-3,4-epoxy-9-hexadecenoic acid. CAS No. 61371-61-7. Molecular formula: C18H30O3. Mole weight: 294.43. | |
| Coprine | It is produced by the strain of Coprinus atramentarius. It can affect the liver to degrade ethanol. Synonyms: N-(1-hydroxycyclopropyl)-L-glutamine; N(5)-(1-Hydroxycyclopropyl)-L-glutamine. CAS No. 58919-61-2. Molecular formula: C8H14N2O4. Mole weight: 202.21. | |
| Corallopyronin A | It is produced by the strain of Corallococcus (Myxococcus) coralloides. It is a bacterial RNA synthase inhibitor, mainly resistant to gram-positive bacteria. Synonyms: methyl ((R,E)-5-(4-hydroxy-3-((R,2E,4E,9Z,12E)-8-hydroxy-2,5,9-trimethyltetradeca-2,4,9,12-tetraenoyl)-2-oxo-2H-pyran-6-yl)hex-1-en-1-yl)carbamate. CAS No. 93195-32-5. Molecular formula: C30H41NO7. Mole weight: 527.65. | |
| Corallopyronin B | It is produced by the strain of Corallococcus (Myxococcus) coralloides. It is a bacterial RNA synthase inhibitor, mainly resistant to gram-positive bacteria. Synonyms: methyl ((R,E)-5-(4-hydroxy-3-((R,2E,4E,9Z,12E)-8-hydroxy-2,5,9-trimethylpentadeca-2,4,9,12-tetraenoyl)-2-oxo-2H-pyran-6-yl)hex-1-en-1-yl)carbamate. CAS No. 93195-33-6. Molecular formula: C31H43NO7. Mole weight: 541.67. | |
| Corallopyronin C | It is produced by the strain of Corallococcus (Myxococcus) coralloides. It is a bacterial RNA synthase inhibitor, mainly resistant to gram-positive bacteria. Synonyms: [(E)-5-(4-Hydroxy-5-{(E)-2-methyl-4-[2-methyl-5-((1Z,4E)-1-methyl-hexa-1,4-dienyl)-tetrahydro-furan-2-yl]-but-3-enoyl}-6-oxo-6H-pyran-2-yl)-hex-1-enyl]-carbamic acid methyl ester; [5-[4-Hydroxy-3-[2-methyl-1-oxo-4-[tetrahydro-2-methyl-5-(1-methyl-1,4-hexadienyl)furan-2-yl]-3-butenyl]-2-oxo-2H-pyran-6-yl]-1-hexenyl]carbamic acid methyl ester. CAS No. 96717-74-7. Molecular formula: C30H41NO7. Mole weight: 527.65. | |
| Coriolin | It is produced by the strain of Coriolus consors. It has anti-gram-positive bacteria, negative bacteria (weak), yeast and vaginal trichomoniasis activities. Coriolin of 5 μg/mL can inhibit the growth of yoshida sarcoma 61.6%. It had no inhibitory effect on Ehrlich ascites carcinoma in animals. Synonyms: (1aS, 3S, 7aR)-3bβ, 4, 5, 6, 6aβ, 7-Hexahydro-4β, 7α-dihydroxy-3aα, 5, 5-trimethylspiro[cyclopenta[4, 5]pentaleno[1, 6a-b]oxirene-3(3aH), 2'-oxiran]-2(1aH)-one; (3S, 7aR)-3aα, 5, 5-Trimethyl-4β, 7α-dihydroxy-1aβ, 2, 3bβ, 4, 5, 6, 6aβ, 7-octahydrospiro[cyclopenta[4, 5]pentaleno[1, 6a-b]oxirene-3(3aH), 2'-oxirane-2-one; (-)-Coriolin; Coriolin A. CAS No. 33404-85-2. Molecular formula: C15H20O5. Mole weight: 280.32. | |
| Coriolin B | It is produced by the strain of Coriolus consors. It has anti-gram-positive bacteria, negative bacteria (weak), yeast and vaginal trichomoniasis activities. Coriolin of 5 μg/mL can inhibit the growth of yoshida sarcoma 61.6%. It had no inhibitory effect on Ehrlich ascites carcinoma in animals. Synonyms: (1aR, 3S, 7aR)-1aβ, 2, 3bβ, 4, 5, 6, 6aβ, 7-Octahydro-2α, 7α-dihydroxy-4β-octanoyloxy-3aα, 5, 5-trimethylspiro[cyclopenta[4, 5]pentaleno[1, 6a-b]oxirene-3(3aH), 2'-oxirane]. CAS No. 33400-89-4. Molecular formula: C23H36O6. Mole weight: 408.53. | |
| Coriolin C | It is produced by the strain of Coriolus consors. It has anti-gram-positive bacteria, negative bacteria (weak), yeast and vaginal trichomoniasis activities. Coriolin of 5 μg/mL can inhibit the growth of yoshida sarcoma 61.6%. It had no inhibitory effect on Ehrlich ascites carcinoma in animals. Synonyms: 3b, 4, 5, 6, 6a, 7-Hexahydro-7-hydroxy-4-(2-hydroxyoctanoyloxy)-3a, 5, 5-trimethylspiro[cyclopenta[4, 5]pentaleno[1, 6a-b]oxirene-3(3aH), 2'-oxiran]-2(1aH)-one. CAS No. 33400-90-7. Molecular formula: C23H34O7. Mole weight: 422.51. | |
| Coronatine | It is produced by the strain of Pseudomonas coronafaciens, P. glycinea. It is a metabolite that is toxic to plants. Synonyms: 2-Ethyl-1-{[ (6-ethyl-1-oxo-2, 3, 3a, 6, 7, 7a-hexahydro-1H-inden-4-yl) (hydroxy) methylidene]amino}cyclopropane-1-carboxylic acid; (+)-coronatine. Grades: 95%. CAS No. 62251-96-1. Molecular formula: C18H25NO4. Mole weight: 319.40. | |
| Cororubicin | It is produced by the strain of Micromonospora sp. JY16. It has anti-tumor cell activity. The IC50 of KB cells and N18-RE-105 cells was 4.3 X 10-6 mol/L and 0.84 X 10-6 mol/L, respectively. CAS No. 160605-92-5. Molecular formula: C48H62N2O21. Mole weight: 1003.00. | |
| Corticotropin | Corticotropin is a peptide hormone involved in the stress response. Synonyms: Adrendcorticotrophic hormone; ACTH; ACTH (1-39); Acthar; Adrenocorticotrophin; Adrenocorticotropic hormone; Corticotrophin; H.P. acthar gel. CAS No. 9002-60-2. Molecular formula: C207H308N56O58S. Mole weight: 4541.07. | |
| Cortinarin A | It is produced by the strain of Cortinarius speciosissimus, C. orellanus and C. orellanoides. It is a peptide antibiotic with vasoconstriction and renal toxicity. CAS No. 88025-84-7. Molecular formula: C58H87N13O12S. Mole weight: 1190.45. | |
| Cortinarin B | It is produced by the strain of Cortinarius speciosissimus, C. orellanus and C. orellanoides. It is a peptide antibiotic with vasoconstriction and renal toxicity. CAS No. 89286-74-8. Molecular formula: C57H85N13O12S. Mole weight: 1176.43. | |
| Cortinarin C | It is produced by the strain of Cortinarius speciosissimus, C. orellanus and C. orellanoides. It is a peptide antibiotic. CAS No. 88025-85-8. Molecular formula: C15H17N3O3. Mole weight: 287.31. | |
| Corynecandin | It is produced by the strain of Coryneum modonium AB 2020T-223. It is a glycolipid antibiotic with antifungal activity. The antifungal spectrum and antifungal activity are similar to Papulacandin. Synonyms: D-Glucitol, 1,5-anhydro-1-C-(2,4-dihydroxy-6-(hydroxymethyl)phenyl)-4-O-(6-O-((2E,4Z)-1-oxo-2,4-decadienyl)-beta-D-galactopyranosyl)-, 3-((2E,4E)-7-hydroxy-2,8-dimethyl-2,4-decadienoate)-. CAS No. 199169-60-3. Molecular formula: C41H60O16. Mole weight: 808.90. | |
| Corynecin ? | It is produced by the strain of Corynebacterium KY-4339. It has weak activity against gram-positive bacteria and gram-negative bacteria. Synonyms: N-[(1R,2R)-1-[(Acetyloxy)methyl]-2-hydroxy-2-(4-nitrophenyl)ethyl]acetamide. Grades: >99% by HPLC. CAS No. 40958-11-0. Molecular formula: C13H16N2O6. Mole weight: 296.28. | |
| Corynecin I | It is produced by the strain of Corynebacterium KY-4339. It has weak activity against gram-positive bacteria and gram-negative bacteria. Synonyms: N-[(1R,2R)-2-Hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]acetamide; D-threo-2-Acetamido-1-(4-nitrophenyl)-1,3-propanediol; D-threo-2-Acetamido-1-p-nitrophenyl-1,3-propanediol; n-acetyl-p-nitrophenylserinol. Grades: >99% by HPLC. CAS No. 4423-58-9. Molecular formula: C11H14N2O5. Mole weight: 254.24. | |
| Corynecin II | It is produced by the strain of Corynebacterium KY-4339. It has weak activity against gram-positive bacteria and gram-negative bacteria. Synonyms: D-threo-1-p-Nitrophenyl-2-propionamido-1,3-propanediol; N-[(1R,2R)-2-Hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]propanamide; d-threo-2-(Propionamido)-1-(p-nitrophenyl)-1,3-propanediol. Grades: >99% by HPLC. CAS No. 35098-52-3. Molecular formula: C12H16N2O5. Mole weight: 268.27. | |
| Corynecin III | It is produced by the strain of Corynebacterium KY-4339. It has weak activity against gram-positive bacteria and gram-negative bacteria. Synonyms: Methamphenicol; dimethylamphenicol; N-[(1R,2R)-1-(Hydroxymethyl)-2-hydroxy-2-(4-nitrophenyl)ethyl]-2-methylpropanamide; N-[(1R,2R)-2-Hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]-2-methylpropanamide; d-threo-2-Isobutyramido-1-(p-nitrophenyl)-1,3-propanediol; N-[β-Hydroxy-α-(hydroxymethyl)-p-nitrophenethyl]-2-methyl-D-threo-propionamide. Grades: >99% by HPLC. CAS No. 18048-95-8. Molecular formula: C13H18N2O5. Mole weight: 282.29. | |
| Corynecin V | It is produced by the strain of Corynebacterium KY-4339. It has weak activity against gram-positive bacteria and gram-negative bacteria. Synonyms: [R-(R*,R*)]-N-[1-[(Acetyloxy)methyl]-2-hydroxy-2-(4-nitrophenyl)ethyl]-propanamide. Grades: >99% by HPLC. CAS No. 40958-12-1. Molecular formula: C14H18N2O6. Mole weight: 310.30. | |
| Cosmomycin C | It is an anthracycline antibiotic produced by the strain of Streptomyces cyaneus (A-447). It has anti-tumor and gram-positive bacteria activity. It can inhibit the growth of P388 murine lymphocytic leukemia cells. Synonyms: Antibiotic A-447B; (3''S)-3''-Hydroxycytorhodin A; 3B-Hydroxycytorhodin A; A-447B; β-Rhodomycin S2; 5,12-Naphthacenedione, 8-ethyl-7,8,9,10-tetrahydro-1,6,8,11-tetrahydroxy-10-[[2,3,6-trideoxy-4-O-[2,6-dideoxy-4-O-[(2S,5S,6S)-tetrahydro-5-hydroxy-6-methyl-2H-pyran-2-yl]-a-L-lyxo-hexopyranosyl]-3-(dimethylamino)-a-L-lyxo-hexopyranosyl]oxy]-7-[[2,3,6-trideoxy-3-(dimethylamino)-4-O-[(2S,5S,6S)-tetrahydro-6-methyl-5-[[(2S,5S,6S)-tetrahydro-5-hydroxy-6-methyl-2H-pyran-2-yl]oxy]-2H-pyran-2-yl]-a-L-lyxo-hexopyranosyl]oxy]-,(7R,8R,10S)-. CAS No. 55945-22-7. Molecular formula: C60H88N2O21. Mole weight: 1173.34. | |
| Cosmomycin D | It is an anthracycline antibiotic produced by the strain of Streptomyces cyaneus (A-447). It has anti-tumor activity. It can inhibit the growth of P388 murine lymphocytic leukemia cells. Synonyms: (3''S,3'''''S)-3'',3'''''-Dihydroxycytorhodin A; 1-Deoxyobelmycin D; 3B,3E-Dihydroxycytorhodin A; A-447A; Antibiotic A-447A; 5,12-Naphthacenedione, 8-ethyl-7,8,9,10-tetrahydro-1,6,8,11-tetrahydroxy-7,10-bis((2,3,6-trideoxy-4-O-(2,6-dideoxy-4-O-((2S,5S,6S)-tetrahydro-5-hydroxy-6-methyl-2H-pyran-2-yl)-alpha-L-lyxo-hexopyranosyl)-3-(dimethylamino)-alpha-L-lyxo-hexopyranosyl)oxy)-, (7R,8R,10S)-. CAS No. 95676-81-6. Molecular formula: C60H88N2O22. Mole weight: 1189.34. | |
| Cotrimoxazole | Cotrimoxazole is a fixed antibiotic composed of trimethoprim and sulfamethoxazole. It blocks the synthesis of nucleotides to inhibit cellular metabolism in bacteria. Synonyms: CO-Trimoxazole; Trimosulfa; Trimethoprimsulfa; Trimforte; Sulfamethoxazole-trimethoprim. CAS No. 8064-90-2. Molecular formula: C24H29N7O6S. Mole weight: 543.59. | |
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