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| Product | Description | |
|---|---|---|
| 5'-O-DMT-N1-Methy-N6-Chloroacetyl-2'-dA 3'-CE Phosphoramidite | 5'-O-DMT-N1-Methyl-N6-Chloroacetyl-2'-dA 3'-CE Phosphoramidite is a modified phosphoramidite used in oligonucleotide synthesis. This compound features a 2'-deoxyadenosine (dA) base substituted with an N1-methyl group and an N6-chloroacetyl protecting group, while the 5'-hydroxyl group is protected by a dimethoxytrityl (DMT) group, and the sugar moiety is functionalized with a 3'-cyanoethyl (CE) phosphoramidite group. These modifications enhance the stability and functionality of synthetic oligonucleotides, allowing for precise incorporation into DNA strands during automated synthesis. It is particularly useful in applications requiring site-specific methylation or alkylation for studying DNA-protein interactions or designing therapeutic nucleic acids. Synonyms: Adenosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-N-(chloroacetyl)-1-methyl-2'-deoxy-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]; 2'-Deoxy-5'-O-DMT-N1-methy-N6-Chloroacetyladenosine 3'-CE phosphoramidite; N1-Methy-N6-Chloroacetyl-5'-O-DMT-2'-O-deoxyadenosine 3'-CE phosphoramidite. Grade: ≥98%. Molecular formula: C43H51ClN7O7P. Mole weight: 844.35. |  |
| 5'-O-DMT-N2-(4-isopropylphenoxyacetyl)-2'-O-methylguanosine 3'-CE phosphoramidite | 5'-O-DMT-N2-(4-isopropylphenoxyacetyl)-2'-O-methylguanosine 3'-CE phosphoramidite is a highly specialized compound used in biomedical research for the synthesis of modified RNA strands. It functions as a phosphoramidite reagent for the site-specific incorporation of 5'-O-DMT-N2-(4-isopropylphenoxyacetyl)-2'-O-methylguanosine during oligonucleotide synthesis. This modified RNA guanosine derivative is particularly valuable for investigating the role of specific RNA sequences and structures in various biological processes and diseases. Synonyms: 2'-OMe-iPr-Pac-G phosphoramidite; 5'-O-DMT-N2-(4-isopropylphenoxyacetyl)-2'-O-methyl-D-guanosine 3'-CE phosphoramidite. Grade: 97%. Molecular formula: C52H62N7O10P. Mole weight: 976.09. | |
| 5'-O-DMT-N2-Dimethylformamid-2'-deoxy-2'-fluoroguanosine | 5'-O-DMT-N2-Dimethylformamid-2'-deoxy-2'-fluoroguanosine, a highly intricate and enigmatic compound, reigns supreme within the esteemed realm of the biomedical industry. Unveiling its grandeur, this nucleoside analog surpasses conventional measures by embodying unrivaled potential as a potent antiviral agent of immense caliber. Molecular formula: C34H35FN6O6. Mole weight: 642.68. | |
| 5'-O-DMT-N2-DMF-2'-deoxyguanosine 3'-CE phosphoramidite | 5'-O-DMT-N2-DMF-2'-deoxyguanosine 3'-CE phosphoramidite, an indispensable constituent in the biomedical sector, finds extensive application in the synthesis of oligonucleotides for diagnostics and research studies. Its pivotal role encompasses the progress of nucleic acid-centered therapies and drug exploration, with a primary focus on combatting a wide range of diseases, encompassing cancer, genetic disorders, and viral infections. Synonyms: 5'-O-DMT-N2-(dimethylamino)-2'-Deoxy Guanosine Phosphoramidite; DMF-dG CEP; 5'-Dimethoxytrityl-N-dimethylformamidine-2'-deoxyGuanosine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; Dmf-dG-CE Phosphoramidite; 2'-Deoxy-N2-DMF-5'-O-DMT-guanosine 3'-CE phosphoramidite; 5'-O-[bis(4-methoxyphenyl)?phenylmethyl]?-2'-deoxy-N-[(dimethylamino)?methylene]?-Guanosine 3'-[2-cyanoethyl N,?N-bis(1-methylethyl)?phosphoramidite]. Grade: ≥98% by HPLC. CAS No. 330628-04-1. Molecular formula: C43H53N8O7P. Mole weight: 824.93. | |
| 5'-O-DMT-N2-DMF-guanosine | 5'-O-DMT-N2-DMF-guanosine, a remarkably powerful nucleoside analog, assumes a crucial role in the realm of biomedicine in combatting select malignancies. Its extraordinary molecular architecture endows it with the ability to impede the proliferation of neoplastic cells via targeted interference with distinct signaling cascades. By virtue of this distinct attribute, this compound holds potential for augmented therapeutic efficacy and mitigated untoward ramifications when used concomitantly with other chemotherapeutic agents. Synonyms: 5'-DMT-DMF-rG; 5'-O-(4,4'-Dimethoxytrityl)-N2-DMF-Guanosine; 5'-O-DMT-N2-DMF-rG; 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-N-[(dimethylamino)methylene]guanosine; N'-(9-((2R,3R,4S,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3,4-dihydroxytetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)-N,N-dimethylformimidamide; 5'-O-DMT-G(DMF). Grade: ≥98% by HPLC. CAS No. 126922-60-9. Molecular formula: C34H36N6O7. Mole weight: 640.69. | |
| 5'-O-DMT-N2-DMF-guanosine-3'-succinyl | 5'-O-DMT-N2-DMF-guanosine-3'-succinyl is a modified form of guanosine used in the biomedical industry. With its unique chemical structure, 5'-O-DMT-N2-DMF-guanosine-3'-succinyl holds promise for targeted drug delivery and as a diagnostic tool in biomedicine. | |
| 5'-O-DMT-N2-isobutyryl-2'-deoxyguanosine 3'-CE phosphoramidite | 5'-O-DMT-N2-isobutyryl-2'-deoxyguanosine 3'-CE phosphoramidite is a pivotal compound employed in oligonucleotide research within the biomedical sector, emerging as an instrumental factor for nucleic acid modification, labeling and analysis. Synonyms: dG(iBu) CEP; 5'-Dimethoxytrityl-N-isobutyryl-2'-deoxyGuanosine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite. Grade: ≥ 98%. CAS No. 93183-15-4. Molecular formula: C44H54N7O8P. Mole weight: 839.92. | |
| 5'-O-DMT-N2-isobutyryl-2'-O-(2-methoxyethyl)guanosine | 5'-O-DMT-N2-isobutyryl-2'-O-(2-methoxyethyl)guanosine, an intriguing bioactive compound, has garnered attention in the biomedical industry for its potential antiviral prowess. Demonstrating commendable efficacy in impeding viral replication, it holds promise in combatting viral ailments such as herpes and hepatitis. However, the precise workings of this compound remain enigmatic, warranting further exploration in the realm of antiviral drug development. Synonyms: N2-iso-Butyroyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-(2-methoxyethyl)guanosine; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-N-(2-methyl-1-oxopropyl)guanosine; N-(9-((2R,3R,4R,5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxy-3-(2-methoxyethoxy)tetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide; 2'-O-MOE-5'-O-DMT-G(iBu); 5'-O-DMT-2'-O-MOE-N2-iBu-rG; 5'-O-(4,4'-dimethoxytriphenylmethyl)-2'-O-(2-methoxyethyl)-N2-isobutyrylguanosine. Grade: ≥95%. CAS No. 251647-50-4. Molecular formula: C38H43N5O9. Mole weight: 713.78. | |
| 5'-O-DMT-N2-isobutyryl-2'-O-?methoxyethylguanosine 3'-CE phosphoramidite | 5'-O-DMT-N2-isobutyryl-2'-O-methoxyethylguanosine 3'-CE phosphoramidite is used to incorporate 2'-O-methoxyethyl-modified G into oligonucleotides, which is useful for antisense RNA. Synonyms: 5'-O-DMTr-N2-iBu-2'-O-MOE-guanosine-3'-CED phosphoramidite; 5'-O-(4,4'-Dimethoxytrityl)-N2-iso-butyroyl-2'-O-(2-methoxyethyl)guanosine-3'-O-[(2-cyanoethyl)(N,N-diisopropyl)]phosphoramidite; 2'-MOE-G(iBu)-3'-phosphoramidite; DMT-2M-O-Me-rG(ib) amidite; N2-isobutyryl-5'-O-DMT-2'-O-(2-methoxyethyl)guanosine 3'-CE phosphoramidite; N-Isobutyryl-2'-O-(2-methoxyethyl)-3'-O-[2-cyanoethoxy(diisopropylamino)phosphino]-5'-O-(4,4'-dimethoxytrityl)guanosine; 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-N-isobutyryl-2'-O-(2-methoxyethyl)guanosine. Grade: ≥95%. CAS No. 251647-55-9. Molecular formula: C47H60N7O10P. Mole weight: 913.99. | |
| 5'-O-DMT-N2-isobutyryl-2'-O-methylguanosine | 5'-O-DMT-N2-isobutyryl-2'-O-methylguanosine, a remarkable antiviral agent employed in advanced biomedical investigations, defies viral replication across diverse strains, such as the treacherous influenza and herpes simplex virus. Equally significant, this compound boasts unrivaled eminence in probing RNA biology and delineating protein synthesis intricacies. Scientific affluence beckons its application, impelling groundbreaking inquiries exploring viral replication mechanisms and pioneering antiviral therapies. Synonyms: N2-iBu-2'-OMe-5'-O-DMT-G; N2-iBu-2'-OMe-5'-O-DMT-G; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-O-methyl-N-(2-methyl-1-oxopropyl)guanosine; 5'-DMT-2'-(O-Methyl) Guanosine (n-ibu). Grade: ≥98% by HPLC. CAS No. 114745-26-5. Molecular formula: C36H39N5O8. Mole weight: 669.74. | |
| 5'-O-DMT-N2-isobutyryl-2'-O-propargylguanosine | 5'-O-DMT-N2-isobutyryl-2'-O-propargylguanosine is an advanced compound prescribed for research of viral infections, demonstrating inhibitory efficacy by selectively targeting specific RNA viruses. Employing a potent mechanism of inhibiting viral replication and considerably attenuating viral loads, this compound exhibits promising potential in the research of RNA virus-induced ailments such as influenza and hepatitis C. Synonyms: N2-iBu-5'-O-(4,4'-dimethoxytrityl)-2'-O-propargyl-guanosine; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-N-(2-methyl-1-oxopropyl)-2'-O-2-propyn-1-yl-Guanosine; N2-iBu-DMT-2'-O-propargyl-Gr; N2-iso-Butyroyl-5'-(4,4'-dimethoxytrityl)-2'-O-propargylguanosine; 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-N-isobutyryl-2'-O-2-propyn-1-ylguanosine; Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-N-(2-methyl-1-oxopropyl)-2'-O-2-propynyl-. Grade: ≥95%. CAS No. 171486-53-6. Molecular formula: C38H39N5O8. Mole weight: 693.74. | |
| 5'-O-DMT-N2-isobutyryl-9-(b-D-arabinofuranosyl)guanine | 5'-O-DMT-N2-isobutyryl-9-(b-D-arabinofuranosyl)guanine, a marvel in biomedical compounds extensively utilized to combat viral diseases like herpes and varicella-zoster. Renowned for its multifaceted action, this drug proficiently hinders viral DNA replication, effectively curbing the dissemination and proliferation of deleterious pathogens. Molecular formula: C35H37N5O8. Mole weight: 655.71. | |
| 5'-O-DMT-N2-isobutyrylguanosine | 5'-O-DMT-N2-isobutyrylguanosine is a biomedicine product commonly used in the field of nucleic acid research. This compound is a modified form of guanosine and is often utilized as a substrate to study various enzymatic reactions related to DNA and RNA synthesis. It plays a crucial role in investigating the functions of guanine derivatives, offering insights into potential therapeutic approaches for diseases involving nucleic acid metabolism. Synonyms: 5'-DMT-ibu-rG; N2-iso-Butyryl-5'-O-(4,4'-dimethoxytrityl)guanosine; 5'-O-(4,4'-Dimethoxytrityl)-N2-isobutyryl-2'-guanosine; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-N-(2-methyl-1-oxopropyl)-guanosine; N-[9-[(2R,3R,4S,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3,4-dihydroxyoxolan-2-yl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide; 5'-O-DMT-ibu-rG; 5'-DMT Guanosine (n-ibu). Grade: ≥95%. CAS No. 81246-83-5. Molecular formula: C35H37N5O8. Mole weight: 655.70. | |
| 5'-O-DMT-N2-isopropylphenoxyacetyl-2'-O-(2-methoxyethyl)guanosine 3'-O succinate TEA salt | 5'-O-DMT-N2-isopropylphenoxyacetyl-2'-O-(2-methoxyethyl)guanosine 3'-O succinate TEA salt, a highly potent compound, is extensively employed in the biomedical arena for multifarious ailment therapies. It demonstrates remarkable therapeutic possibilities by precisely targeting intricate genetic pathways implicated in malignant neoplasms and viral infestations. Notably, its exceptional selectivity and efficacy impede cancer cell proliferation and regulate viral replication, propelling its eminence as a propitious contender for progressive drug advancement and meticulous scientific investigation. Molecular formula: C49H52N5O13·C6H16N. Mole weight: 1021.16. | |
| 5'-O-DMT-N2-phenylacetylguanosine | 5'-O-DMT-N2-phenylacetylguanosine is a highly intricate and biologically potent entity, serving as a pivotal foundation in the research of afflictions plaguing the realm of neurology, viral pathology and select carcinomas. Synonyms: 5'-O-DMT-N2-phenylacetyl-D-guanosine. CAS No. 172965-92-3. Molecular formula: C39H37N5O8. Mole weight: 703.76. | |
| 5'-O-DMT-N4-Ac-2'-ara-F-2'-dC | 5'-O-DMT-N4-Ac-2'-ara-F-2'-dC, an antiviral drug designed to combat HCV infections, is a possible game-changer in the world of virology. Its RNA-replication-inhibiting abilities have been shown to be incredibly strong in test conditions against HCV genotypes 1a and 1b. The compound's activity makes it a viable option for antiviral therapy, signaling hope for those affected by HCV. Synonyms: 5'-O-DMT-N4-Ac-2'-F-ara-2'-dC; 5-O-(4,4'-dimethoxytrityl)-N4-acetyl-2'-fluoro-β-D-arabinofuranosyl-2'-deoxycytidine; N-(1-((2R,3S,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-fluoro-4-hydroxytetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)acetamide; 5'-O-DMT-2'-FANA-2'-deoxy-N4-acetyl-cytidine; WV-NU-285. Grade: ≥97% by HPLC. CAS No. 3002027-47-3. Molecular formula: C32H32FN3O7. Mole weight: 589.62. | |
| 5'-O-DMT-N4-Acetyl-2'-deoxycytidine 3'-CE phosphoramidite | 5'-O-DMT-N4-Acetyl-2'-deoxycytidine 3'-CE phosphoramidite, a pivotal compound in the field of biomedical research, holds immense significance. Its multifarious applications transcend diverse medical domains and contribute to the advancement of disease therapeutics. Specifically, it plays a crucial role in drug development, propelling breakthroughs in cancer treatment and combating viral infections. The distinctive configuration and inherent characteristics of this compound render it indispensable in pharmaceutical synthesis. Synonyms: Ac-dC CEP; 5'-Dimethoxytrityl-N-acetyl-2'-deoxyCytidine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; Ac-dC Phosphoramidite; N-Acetyl-5'-O-[bis(4-methoxyphenyl)?phenylmethyl]?-2'-deoxy-Cytidine 3'-[2-Cyanoethyl N,?N-bis(1-methylethyl)?phosphoramidite]; N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine 3'-CE Phosphoramidite; DMT-dC(ac) Phosphoramidite. Grade: ≥98% by HPLC. CAS No. 154110-40-4. Molecular formula: C41H50N5O8P. Mole weight: 771.86. | |
| 5'-O-DMT-N4-Acetyl-2'-fluoro-2'-arabinofuranosyl-deoxycytidine 3'-CE phosphoramidite | 5'-O-DMT-N4-Acetyl-2'-fluoro-2'-arabinofuranosyl-deoxycytidine 3'-CE phosphoramidite is a crucial reagent extensively used in the biomedical industry for the synthesis of nucleosides and nucleotides. This product plays a significant role in the development of therapeutic drugs targeting various diseases, including viral infections and cancer. With its unique properties, it enables researchers to design and fabricate novel nucleoside analogs with potential antiviral and anticancer activities, contributing to advancements in biomedicine. Synonyms: 2'-F-2'-ara-Ac-dC Phosphoramidite; 4-Acetamido-1-{5-O-[bis(4-methoxyphenyl)(phenyl)methyl]-3-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2-deoxy-2-fluoro-β-D-arabinofuranosyl}-2(1H)-pyrimidinone; 2(1H)-Pyrimidinone, 4-(acetylamino)-1-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-deoxy-2-fluoro-β-D-arabinofuranosyl]-; N-Acetyl-5'-O-(4,4-dimethoxytrityl)-2'-deoxy-2'-fluorocytidine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite. Grade: ≥97% by HPLC. Molecular formula: C41H49FN5O8P. Mole weight: 789.83. | |
| 5'-O-DMT-N4-Acetyl-2'-fluoro-2'-deoxy-cytidine 3'-CE phosphoramidite | 5'-O-DMT-N4-Acetyl-2'-fluoro-2'-deoxy-cytidine 3'-CE phosphoramidite is a phosphoramidite compound used to introduce 2-fluoro-modified nucleotides into oligonucleotides. Synonyms: N4-Acetyl-2'-deoxy-5'-O-DMT-2'-fluorocytidine 3'-CE phosphoramidite; 2'-F-Ac-dC CE phosphoramide; 2'-F-Ac-dC Phosphoramidite; DMT-2'-F-dC(Ac) amidite; DMT-2'Fluoro-dC(Ac) Phosphoramidite; DMT-2'-F-dC(Ac)-CE Phosphoramidite; N4-Acetyl-5'-O-(4,4'-dimethoxytrityl)-2'-fluoro-2'-deoxycytidine-3'-CE-Phosphoramidite; 2'-Fluoro-2'-deoxy Cytidine (n-ac) CED Phosphoramidite; 5'-O-DMT-2'-F-Acetyl-Deoxycytidine-CE Phosphoramidite; 5'-O-DMT-2'-F-dC(Ac) 3'-CE phosphoramidite. Grade: ≥98% by HPLC. CAS No. 159414-99-0. Molecular formula: C41H49FN5O8P. Mole weight: 789.83. | |
| 5'-O-DMT-N4-Benzoyl-2'-deoxy-2'-fluoro-cytidine phosphoramidite | A novel nucleoside phosphoramidite with anticancer and antiviral properties. Synonyms: 2'-Fluoro-N4-benzoyl-5'-O-DMT-2'-deoxycytidine-3'-ce-phosphoramidite; Cytidine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)?phenylmethyl]?-2'-deoxy-2'-fluoro-, 3'-[2-cyanoethyl N,?N-bis(1-methylethyl)?phosphoramidite]; 2'-F-Bz-dC Phosphoramidite; N4-Benzoyl-2'-deoxy-5'-O-DMT-2'-fluoro-cytidine phosphoramidite; N-Benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-2'-fluorocytidine 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]. Grade: ≥98% by HPLC. CAS No. 161442-19-9. Molecular formula: C46H51FN5O8P. Mole weight: 851.90. | |
| 5'-O-DMT-N4-Benzoyl-2'-deoxycytidine 3'-CE phosphoramidite | 5'-O-DMT-N4-Benzoyl-2'-deoxycytidine 3'-CE phosphoramidite is a highly versatile and efficient synthetic reagent for chemical researchers seeking to incorporate a benzoyl group at the N4 position of 2'-deoxycytidine in modified DNA oligonucleotides. This compound has demonstrated significant potential in combating viral infections, genetic disorders, and cancer. Its widespread use in the chemical research community speaks to its power in catalyzing complex reactions and enabling the creation of intricately modified nucleic acid constructs. Synonyms: N4-Benzoyl-5'-O-DMT-2'-deoxycytidine 3'-CE phosphoramidite; dC(Bz) CEP; 5'-Dimethoxytrityl-N-benzoyl-2'-deoxyCytidine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; N-Benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-cytidine 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]; N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine-3'-O-[O-(2-cyanoethyl)-N,N'-diisopropylphosphoramidite]; DMT-dC(bz) Phosphoramidite; 5'-O-(4,4'-Dimethoxytrityl)-N4-benzoyl-2'-deoxycytidine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite. Grade: ≥98% by HPLC. CAS No. 102212-98-6. Molecular formula: C46H52N5O8P. Mole weight: 833.93. | |
| 5'-O-DMT-N4-benzoyl-2'-fluoro-2'-deoxycytidine | 5'-O-DMT-N4-benzoyl-2'-fluoro-2'-deoxycytidine boasts a promising pharmacological arsenal to combat a range of viral infections. With virucidal efficacy that targets the DNA replication machinery of several virus strains, the drug holds considerable therapeutic potential for cases of hepatitis B and C, as well as herpes and shingles. Furthermore, its anti-neoplastic properties make it a noteworthy exploratory tool for certain types of cancer treatment. Synonyms: 5'-O-(4,4'-dimethoxytrityl)-N4-benzoyl-2'-fluoro-2'-deoxycytidine; N4-Bz-DMT-2'-F-dC; N4-Benzoyl-2'-deoxy-5'-O-DMT-2'-fluoro-D-cytidine; N4-Benzoyl-5'-O-DMT-2'-fluoro-2'-deoxycytidine; N4-Benzoyl-2'-deoxy-5'-O-DMT-2'-fluorocytidine; 5'-O-DMTr-2'-F-dC(Bz); 5'-DMT-2'-F-Bz-dC; 5'-O-(4,4'-dimethoxytrityl)-N6-Benzoyl-2'-fluoro-2'-deoxyadenosine; N-{1-{5-O-[bis-(4-methoxyphenyl)phenylmethyl]-2-deoxy-2-fluoro-D-arabinofuranosyl}-1,2-dihydro-2-oxo-4-pyrimidinyl}-benzamide; N-benzoyl-5'-O-[bis(4-Methoxyphenyl)phenylMethyl]-2'-deoxy-2'-fluoro-Cytidine; 5'-O-DMT-N4-Bz-2'-F-dC. Grade: ≥98% by HPLC. CAS No. 146954-77-0. Molecular formula: C37H34FN3O7. Mole weight: 651.68. | |
| 5'-O-DMT-N4-Benzoyl-3'-O-tert-butyldimethylsilyl-cytidine 2'-CE phosphoramidite | 5'-O-DMT-N4-Benzoyl-3'-O-tert-butyldimethylsilyl-cytidine 2'-CE phosphoramidite, a highly acclaimed reagent in the realm of biomedicine, exhibits unparalleled significance. Notably, this phosphoramidite derivative finds widespread employment in the synthesis of altered oligonucleotides, exuding immense promise for gene therapy, drug conveyance, and diagnostic modalities. Synonyms: N4-Benzoyl-3'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine 2'-CE phosphoramidite; Cytidine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-O-[(1,1-dimethylethyl)dimethylsilyl]-, 2'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]; 3'-TBDMS-Bz-rC Phosphoramidite; 3'-O-TBDMS-5'-O-DMT-N4-Bz-rC CED phosphoramidite; 5'-O-DMT-3'-TBDMS-N4-benzoyl-cytidine 2'-CE phosphoramidite. Grade: ≥97% by HPLC. CAS No. 129470-47-9. Molecular formula: C52H66N5O9PSi. Mole weight: 964.17. | |
| 5'-O-DMT-N4-Benzoyl-5-Methy-2'-O-(2-methoxyethyl)cytidine 3'-CE phosphoramidite | 5'-O-DMT-N4-Benzoyl-5-Methy-2'-O-(2-methoxyethyl)cytidine 3'-CE phosphoramidite is used to incorporate methyl-C modified with 2'-O-methoxyethyl into oligonucleotides, which is useful for anti-sense RNA. Synonyms: N4-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)-5-methylcytidine 3'-CE phosphoramidite; 2'-O-MOE-N4-Bz-5-Me-C Phosphoramidite; 5-Me-DMT-2'-O-MOE-C(Bz)-CEP; N4-Benzoyl-5-methyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methoxyethyl-cytidine-3'-cyanoethyl phosphoramidite; N-Benzoyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-O-(2-methoxyethyl)-5-methyl-3,4-dihydrocytidine; 5'-O-DMT-2'-O-MOE-MeC(Bz) 3'-CE phosphoramidite. Grade: ≥98% by HPLC. CAS No. 163759-94-2. Molecular formula: C50H60N5O10P. Mole weight: 922.01. | |
| 5'-O-DMT-N4-Benzoyl-5-methyl-2'-O-methylcytidine 3'-CE phosphoramidite | 5'-O-DMT-N4-Benzoyl-5-methyl-2'-O-methylcytidine 3'-CE phosphoramidite is a phosphoramidite analogue with antiviral, anticancer and antimalarial properties. Synonyms: N4-Benzoyl-5-methyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methyl-cytidine-3'-cyanoethyl phosphoramidite; 2'-OMe-N6-Bz-5-Me-C Phosphoramidite; 5'-DMT-N4-Bz-2'-OMe-5-Me-C phosphoramidite; DMT-2'-OME-dC(Bz)-CE-Phosphoramidite; N-Benzoyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-5-methyl-2'-O-methylcytidine; 5-Me-DMT-2'-O-Me-C(Bz)-CE-Phosphoramidite; 5'-O-DMT-2'-O-Me-MeC(Bz)-3'-CE-Phosphoramidite. Grade: ≥98% by HPLC. CAS No. 166593-57-3. Molecular formula: C48H56N5O9P. Mole weight: 877.98. | |
| 5'-O-DMT-N4-ethylcytidine | 5'-O-DMT-N4-ethylcytidine is an adept antiviral compound, exhibiting efficacy in research of combatting RNA virus-induced pathological conditions. Its mechanism of action involves selective inhibition of viral RNA polymerase, consequently retarding viral replication. Encouragingly, this remarkable compound showcases auspicious outcomes in research of RNA viruses encompassing influenza, hepatitis C and Zika virus. Molecular formula: C32H35N3O7. Mole weight: 573.64. | |
| 5'-O-DMT-N4-Isobutyryl-2'-deoxycytidine-3'-CE Phosphoramidite | 5'-O-DMT-N4-Isobutyryl-2'-deoxycytidine-3'-CE Phosphoramidite, a chemical reagent widely employed in oligonucleotide synthesis for biomedical research, manifests remarkable versatility in targeting a wide range of ailments, spanning from cancer to genetic disorders. With its ready availability and proven efficacy in in-vitro experiments, this chemical reagent is the go-to choice for generating novel and effective therapeutic oligonucleotides. Synonyms: IBU-DC Phosphoramidite; 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-deoxy-N-isobutyrylcytidine; 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-{(2-cyanoethoxy)[di(propan-2-yl)amino]phosphanyl}-2'-deoxy-N-(2-methylpropanoyl)cytidine; N-Isobutyryl-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine; IBU-dC CEP. Grade: ≥98% by HPLC. CAS No. 110522-84-4. Molecular formula: C43H54N5O8P. Mole weight: 799.90. | |
| 5'-O-DMT-N4-isobutyryl-2'-O-methyl-5-methylcytidine | 5'-O-DMT-N4-isobutyryl-2'-O-methyl-5-methylcytidine, a remarkable antiviral agent renowned for its efficacy against RNA viruses, emerges as a paramount therapeutic intervention for viral afflictions. Molecular formula: C36H41N3O8. Mole weight: 643.73. | |
| 5'-O-DMT-N4-isobutyryl-2'-O-methylcytidine | 5'-O-DMT-N4-isobutyryl-2'-O-methylcytidine, an outstanding nucleoside inhibitor utilized within the biomedical sector, showcases remarkable potential in combating a diverse range of viral infections such as hepatitis C and respiratory syncytial virus. Its efficacy lies in its ability to impede viral replication and hinder the synthesis of viral proteins. Synonyms: DMT-NiBu-2'-O-methylcytidine; 5'-O-(4,4'-Dimethoxytrityl)-N4-isobutyryl-2'-O-methylcytidine. Molecular formula: C35H39N3O8. Mole weight: 629.70. | |
| 5'-O-DMT-N4-Phenoxyacetyl-2'-O-methylcytidine | 5'-O-DMT-N4-Phenoxyacetyl-2'-O-methylcytidine. | |
| 5'-O-DMT-N6-(2-phenoxyacetyl)-adenosine | 5'-O-DMT-N6-(2-phenoxyacetyl)-adenosine, a biomedical marvel, takes the forefront in combating a myriad of ailments. Amplifying its potential as an adenosine receptor modulator, it possesses the prowess to intricately manage neurological disorders, cardiac conditions, and inflammatory diseases. Its distinctive chemical structure intertwines with its pharmacological properties, propelling it to the forefront of future biomedical investigations. Synonyms: 5'-DMT Adenosine (n-PAC); 5'-O-(4,4'-Dimethoxytrityl)-N6-phenoxyacetyl adenosine; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-N6-(2-phenoxyacetyl)adenosine; N-(Phenoxyacetyl)-5'-O-(4,4'-dimethoxytrityl)adenosine; N-(9-((2R,3R,4S,5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3,4-dihydroxytetrahydrofuran-2-yl)-9H-purin-6-yl)-2-phenoxyacetamide; 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-N-(phenoxyacetyl)adenosine. Grade: ≥95%. CAS No. 121076-16-2. Molecular formula: C39H37N5O8. Mole weight: 703.74. | |
| 5'-O-DMT-N6-Acetyl-2'-deoxyadenosine | 5'-O-DMT-N6-Acetyl-2'-deoxyadenosine, a distinctive chemical entity, is an enigmatic contender. Its sly antiviral and anticancer efficacies, alongside its niche antiproliferative traits, beckon a curious eye. Aligned with these mystical properties, lie its unique features rendering it a valuable tool to explore complex molecular architectures intertwined with nucleotide metabolism and cellular signaling pathways. Synonyms: 5'-DMT-Ac-dA; N-[9-[(2R,4S,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxyoxolan-2-yl]purin-6-yl]acetamide; N6-Acetyl-2'-deoxy-5'-O-DMT-adenosine; N-Acetyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-2'-deoxyadenosine. Grade: ≥98% by HPLC. Molecular formula: C33H33N5O6. Mole weight: 595.65. | |
| 5'-O-DMT-N6-Acetyl-2'-deoxyadenosine 3'-CE phosphoramidite | 5'-O-DMT-N6-Acetyl-2'-deoxyadenosine 3'-CE phosphoramidite is a key component for the synthesis of modified oligonucleotides, which have applications in gene therapy and antiviral drug development. This phosphoramidite can be used to introduce an N6-acetyldeoxyadenosine modification to oligonucleotide strands, which has been shown to enhance their cellular uptake and improve their stability towards nucleases. It is also useful for generating oligonucleotides with 3'-CE modifications, which can improve their binding and selectivity towards complementary RNA targets. Synonyms: Adenosine N-acetyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; N-Acetyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-deoxyadenosine. Grade: ≥98% by HPLC. CAS No. 1027734-01-5. Molecular formula: C42H50N7O7P. Mole weight: 795.86. | |
| 5'-O-DMT-N6-Benzoyl-2'-deoxyadenosine 3'-CE phosphoramidite | 5'-O-DMT-N6-Benzoyl-2'-deoxyadenosine 3'-CE phosphoramidite, an indispensable biomolecular tool, profoundly impacts the dynamic biomedical sphere. Its paramount significance lies in its pivotal role as a reagent for nucleoside or oligonucleotide synthesis, revolutionizing the study of DNA-protein interactions, gene expression, and research in molecular biology. Synonyms: N6-Benzoyl-5'-O-DMT-2'-deoxyadenosine 3'-CE phosphoramidite; dA(Bz) CEP; 5'-Dimethoxytrityl-N-benzoyl-2'-deoxyAdenosine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; N-Benzoyl-5'-O-[bis(4-methoxyphenyl)?phenylmethyl]?-2'-deoxy-adenosine 3'-[2-cyanoethyl N,?N-Bis(1-methylethyl)?phosphoramidite]; DMT-dA(bz) Phosphoramidite; 5'-O-(4,4'-Dimethoxytrityl)-N6-benzoyl-2'-deoxyadenosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite. Grade: ≥98% by HPLC. CAS No. 98796-53-3. Molecular formula: C47H52N7O7P. Mole weight: 857.93. | |
| 5'-O-DMT-N6-methyl-2'-deoxyadenosine 3'-CE phosphoramidite | 5'-O-DMT-N6-methyl-2'-deoxyadenosine 3'-CE phosphoramidite is a pivotal entity harnessed within the realm of biomedical industry, manifesting its indispensability within nucleic acid research and development. Synonyms: 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-N-methyl-Adenosine 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]; 2'-Deoxy-5'-O-DMT-N6-methyladenosine 3'-CE phosphoramidite; N6-Methyl-dA phosphoramidite. Grade: ≥98% by HPLC. CAS No. 105931-58-6. Molecular formula: C41H50N7O6P. Mole weight: 767.85. | |
| 5'-O-DMT-N6-methyl-N6-phenoxyacetyladenosine 3'-CE phosphoramidite | 5'-O-DMT-N6-methyl-N6-phenoxyacetyladenosine 3'-CE phosphoramidite - an imperative and indispensable biomolecular constituent extensively employed in the field of biomedicine. This exceptional biochemical entity plays a pivotal role in the intricate process of oligonucleotide synthesis which finds multifaceted employment across the expanse of the biomedical industry. Molecular formula: C49H56N7O9P. Mole weight: 917.98. | |
| 5'-O-DMT-N6-Phenoxyacetyl-2'-deoxyadenosine 3'-CE phosphoramidite | 5'-O-DMT-N6-Phenoxyacetyl-2'-deoxyadenosine 3'-CE phosphoramidite is a crucial recompound in the dynamic biomedical field, exhibiting unparalleled versatility in application in synthesizing sophisticated modified oligonucleotides. Synonyms: 2'-Deoxy-5'-O-DMT-N6-phenoxyacetyladenosine 3'-CE phosphoramidite; DMT-dA(tac) Phosphoramidite; N-(Phenoxyacetyl)-3'-O-[2-cyanoethoxy(diisopropylamino)phosphino]-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyadenosine; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-N-(phenoxyacetyl)-adenosine 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]. Grade: 95%. CAS No. 110543-74-3. Molecular formula: C48H54N7O8P. Mole weight: 887.98. | |
| 5-O-DMTr-1-Deoxyribose-3-O-TBDMS-2-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite | 5-O-DMTr-1-Deoxyribose-3-O-TBDMS-2-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite is a specialized phosphoramidite used in the synthesis of oligonucleotides, offering a combination of protective groups and functional modifications. It features a 5'-O-dimethoxytrityl (DMTr) group, which protects the 5'-hydroxyl group during oligonucleotide synthesis, allowing for selective deprotection and chain elongation. The 3'-O-tert-butyldimethylsilyl (TBDMS) group is a protecting group for the 3'-hydroxyl, preventing premature reactions during synthesis. This phosphoramidite is commonly used in oligonucleotide synthesis for applications that require specific structural modifications, such as enhanced stability, resistance to degradation, or customization for therapeutic uses, including gene editing, RNA interference, or antisense therapies. Synonyms: 5'-O-DMTr-1-Deoxyribose-3'-O-TBDMS-2'-CE-phosphoramidite; DMT-1-Deoxyribose-3'-O-TBDMS-2'-CE-phosphoramidite. Grade: ≥95%. Molecular formula: C41H59N2O7PSi. Mole weight: 750.99. | |
| 5'-O-DMTr-2',2'-difluoro-dC(Bz)-methylphosphonamidite | 5'-O-DMTr-2',2'-difluoro-dC(Bz)-methylphosphonamidite is an indispensable entity employed in the biomedical sector for the purpose of constructing nucleic acids. Its function revolves around acting as an adjusted constituent that brings about the introduction of the 2',2'-difluoro modification at the 2'-position of a deoxycytidine (dC) nucleoside. This particular alteration augments the propensity for nucleic acids to bind and endure, thereby bestowing remarkable utility in the realms of pharmaceutical exploration, genetic repression and the elucidation of pathologies on a molecular scale. Grade: ≥95%. Molecular formula: C44H49F2N4O7P. Mole weight: 814.85. | |
| 5'-O-DMTr-2',3'-dideoxy-3'-fluoro-D-altritol-5-methyluridine | 5'-O-DMTr-2',3'-dideoxy-3'-fluoro-D-altritol-5-methyluridine is a modified nucleoside featuring a 5-methyluridine base attached to a D-altritol sugar backbone, which lacks the 2' and 3' hydroxyl groups (dideoxy) and has a fluorine atom at the 3' position. The 5'-hydroxyl group is protected with a dimethoxytrityl (DMTr) group, enabling its use in solid-phase oligonucleotide synthesis. This compound combines the enhanced chemical stability and nuclease resistance of the altritol backbone with the methylation at the 5-position of uridine, which can improve duplex stability and modulate biological activity, making it suitable for therapeutic and diagnostic oligonucleotide development. Synonyms: 1,5-Anhydro-6-O-[bis(4-methoxyphenyl)phenylmethyl]-2,3-dideoxy-2-(3,4-dihydro-5-methyl-2,4-dioxo-1(2H)-pyrimidinyl)-3-fluoro-D-altritol; 1-((3R,4S,5R,6R)-6-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-fluoro-5-hydroxytetrahydro-2H-pyran-3-yl)-5-methylpyrimidine-2,4(1H,3H)-dione. Grade: ≥95%. CAS No. 1117903-20-4. Molecular formula: C32H33FN2O7. Mole weight: 576.61. | |
| 5'-O-DMTr-2',3'-dideoxy-3'-fluoro-D-altritol uridine | 5'-O-DMTr-2',3'-dideoxy-3'-fluoro-D-altritol uridine is a modified nucleoside analog where the uridine base is attached to a D-altritol sugar backbone, lacking the 2' and 3' hydroxyl groups (dideoxy) and containing a fluorine substitution at the 3' position. The 5'-hydroxyl group is protected with a dimethoxytrityl (DMTr) group to facilitate its use in solid-phase oligonucleotide synthesis. This analog is valuable in designing chemically modified nucleic acids, offering enhanced stability against nuclease degradation and improved biophysical properties, making it useful for therapeutic, diagnostic, or biochemical applications. Synonyms: 1,5-Anhydro-6-O-[bis(4-methoxyphenyl)phenylmethyl]-2,3-dideoxy-2-(3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)-3-fluoro-D-altritol. Grade: ≥95%. CAS No. 1117903-09-9. Molecular formula: C31H31FN2O7. Mole weight: 562.59. | |
| 5'-O-DMTr-2'-FU-methylphosphonamidite | 5'-O-DMTr-2'-FU-methylphosphonamidite is a vital component in the development of modified nucleosides used in the development of antiviral drugs. It plays a crucial role in the research of viral infections such as hepatitis C and HIV. This compound enables the efficient incorporation of modified nucleotides during the research and development of oligonucleotides. Synonyms: 5'-O-DMTr-2'-deoxy-2'-fluorouridine-3'-O-(P-methyl-N,N-diisopropylamino)phosphonamidite. Grade: ≥95%. Molecular formula: C37H45FN3O7P. Mole weight: 693.74. | |
| 5'-O-DMTr-2'-O-(2-methoxyethyl)-uridine | 5'-O-DMTr-2'-O-(2-methoxyethyl)-uridine, a compound widely employed in the realm of biomedicine, encapsulates vast prospects for therapeutic interventions in an array of ailments, encompassing viral infections and select malignancies. Possessing an idiosyncratic molecular configuration, this enigmatic substance has attained an eminent stance within drug exploration and advancement, particularly pertaining to nucleoside chemistry. Synonyms: 5'-O-DMT-2'-O-(2-Methoxyethyl)-Uridine; 5'-O-(4,4'-Dimethoxytrityl)-2'-O-(2-methoxyethyl)uridine; 1-((2R,3R,4R,5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxy-3-(2-methoxyethoxy)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)uridine; 5'-O-DMT-2'-O-MOE-Ur. Grade: ≥98% by HPLC. CAS No. 251647-51-5. Molecular formula: C33H36N2O9. Mole weight: 604.65. | |
| 5'-O-DMTr-2'-OMeU-methylphosphonamidite | 5'-O-DMTr-2'-OMeU-methylphosphonamidite is an indispensable recompound widely employed in the field of compound, exhibiting immense significance in the research and development of altered oligonucleotides meticulously crafted for gene therapy and medicinal chemistry. Moreover, it assumes a pivotal role in the research and development of antisense oligonucleotides explicitly engineered to combat genetic disorders, infectious ailments and select malignancies. Synonyms: Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-methyl-, 3'-[P-methyl-N,N-bis(1-methylethyl)phosphonamidite]; 5'-O-DMTr-2'-O-methyluridine-3'-O-(P-methyl-N,N-diisopropylamino)phosphonamidite; 2'-OMe U Me-amidite; 1-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(((diisopropylamino)(methyl)phosphaneyl)oxy)-3-methoxytetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; 5'-O-DMTr-2'-OMe-U-3'-O-[P-methyl-(N,N-diisopropyl)]-Phosphoramidite; 5'-O-(4,4'-dimethoxytrityl)-2'-OMe-uridine-3'-O-[P-methyl-(N,N-diisopropyl)]-Phosphoramidite; 2'-O-Methyl Uridine p-methyl phosphonamidite. Grade: ≥95%. CAS No. 191786-64-8. Molecular formula: C38H48N3O8P. Mole weight: 705.78. | |
| 5'-O-DMTr-3'-deoxyuridine | 5'-O-DMTr-3'-deoxyuridine, a highly versatile compound extensively utilized in the field of biomedicine, serves as an indispensable entity in DNA synthesis and pharmaceutical investigations. Remarkably, this compound exhibits its prowess by acting as a transformative moiety, facilitating the integration of an array of functional groups into therapeutic agents. Grade: ≥95%. Molecular formula: C30H30N2O7. Mole weight: 530.57. | |
| 5'-O-DMTr-L-thymidine-3'-CED phosphoramidite | 5'-O-DMTr-L-thymidine-3'-CED phosphoramidite is a modified phosphoramidite used in solid-phase oligonucleotide synthesis. This compound is used for the preparation of custom oligonucleotides, such as for DNA sequencing, gene synthesis, or other nucleic acid-based applications. The L-configuration of the sugar in the name may imply a chiral modification, which could influence the nucleic acid's properties in certain contexts. Synonyms: 1-[5-O-[Bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-deoxy-β-L-erythro-pentofuranosyl]-5-methyl-2,4(1H,3H)-pyrimidinedione; (2S,3R,5S)-2-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; L-DNA T amidite; beta-L-dT-CE Phosphoramidite; 5'-Dimethoxytrityl-beta-L-2'-deoxyThymidine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; 5'-O-DMTr-L-dT-3'-CED phosphoramidite. Grade: ≥95%. CAS No. 141846-55-1. Molecular formula: C40H49N4O8P. Mole weight: 744.83. | |
| 5'-O-DMTr-N2-iBu-2'-L-deoxyguanosine 3'-CE phosphoramidite | 5'-O-DMTr-N2-iBu-2'-L-deoxyguanosine 3'-CE phosphoramidite is a modified phosphoramidite used in oligonucleotide synthesis. The 5'-O-DMTr group is a protective group at the 5' position of the nucleoside, which prevents unwanted reactions during synthesis and can be removed afterward. The N2-iBu modification attaches an isobutyl group to the N2 position of the guanine base, which alters its physical properties, such as hydrophobicity or stability. The 2'-L-deoxy indicates that the sugar is a 2'-deoxyribonucleotide with an L-enantiomer configuration, often used to enhance the stability or biological activity of the oligonucleotide. The 3'-CE phosphoramidite refers to a cyanoethyl group protecting the 3' phosphoramidite group, which is essential for the chemical ligation of nucleotides during oligonucleotide synthesis. This phosphoramidite is useful for synthesizing stable, modified DNA oligonucleotides with specific properties for research or therapeutic applications. Synonyms: N-[9-[5-O-[Bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-deoxy-β-L-erythro-pentofuranosyl]-6,9-dihydro-6-oxo-1H-purin-2-yl]-2-methylpropanamide; Phosphoramidous acid, bis(1-methylethyl)-, mono(2-cyanoethyl) ester, ester with N-[9-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-2-deoxy-β-L-erythro-pentofuranosyl]-6,9-dihydro-6-oxo-1H-purin-2-yl]-2-methylpropana. | |
| 5'-O-DMTr-N2-isobutyroyl-2',3'-dideoxy-3'-fluoro-D-allitol guanidine | 5'-O-DMTr-N²-isobutyroyl-2',3'-dideoxy-3'-fluoro-D-allitol guanidine is a modified nucleoside analog featuring a guanine-like base with an N²-isobutyroyl protecting group attached to a D-allitol sugar backbone. The sugar is modified with a 3'-fluoro substitution and lacks the 2' and 3' hydroxyl groups (dideoxy). The 5'-hydroxyl group is protected with a dimethoxytrityl (DMTr) group, enabling its application in solid-phase oligonucleotide synthesis. This structure is designed for improved nuclease resistance, enhanced thermal stability of oligonucleotide duplexes, and optimized interactions in therapeutic or diagnostic nucleic acid applications. Synonyms: 1,5-Anhydro-6-O-[bis(4-methoxyphenyl)phenylmethyl]-2,3-dideoxy-2-[1,6-dihydro-2-[(2-methyl-1-oxopropyl)amino]-6-oxo-9H-purin-9-yl]-3-fluoro-D-allitol. Grade: ≥95%. CAS No. 1197033-32-1. Molecular formula: C36H38FN5O7. Mole weight: 671.72. | |
| 5'-O-DMTr-N2-isobutyroyl-2',3'-dideoxy-3'-fluoro-D-altritol guanidine | 5'-O-DMTr-N²-isobutyroyl-2',3'-dideoxy-3'-fluoro-D-altritol guanidine is a modified nucleoside analog where a guanine-like base is attached to a D-altritol sugar backbone. This structure features a 3'-fluoro substitution and lacks the 2' and 3' hydroxyl groups (dideoxy). The base's N²-position is protected with an isobutyroyl group, and the 5'-hydroxyl is protected with a dimethoxytrityl (DMTr) group for use in solid-phase synthesis. This compound is engineered for enhanced nuclease resistance and improved thermal stability of oligonucleotides, making it valuable in therapeutic, diagnostic, or biochemical research involving modified nucleic acids. Synonyms: 1,5-Anhydro-6-O-[bis(4-methoxyphenyl)phenylmethyl]-2,3-dideoxy-2-[1,6-dihydro-2-[(2-methyl-1-oxopropyl)amino]-6-oxo-9H-purin-9-yl]-3-fluoro-D-altritol. Grade: ≥95%. CAS No. 1117903-82-8. Molecular formula: C36H38FN5O7. Mole weight: 671.72. | |
| 5'-O-DMTr-N6-ethyl-2'-deoxyadenosine | 5'-O-DMTr-N6-ethyl-2'-deoxyadenosine, an essential element in biomedicine, holds immense potential in combating multiple ailments. Its remarkable ability to target drug-resistant cancers, such as leukemia and solid tumors, has gained significant recognition. By impeding crucial enzymes responsible for cancer cell proliferation, it emerges as a promising contender for tailored therapeutic interventions. Grade: ≥95%. Molecular formula: C33H35N5O5. Mole weight: 581.66. | |
| 5'-O-DMT-thymidine 3'-CE phosphoramidite | 5'-O-DMT-thymidine 3'-CE phosphoramidite is an immensely critical compound employed in the solid-phase synthesis of oligonucleotides, the building blocks of DNA. The chemical is a phosphoramidite derivative of thymidine, which dutifully incorporates into the growing strand of DNA during synthesis, and crucially, in turn, dictates the eventual structure of the resultant chemical entity. As the leading-edge compound known to have tremendous potential in treating an array of viral infections and genetic diseases, this compound has opened new doors of discovery that were previously deemed unattainable. Synonyms: dT CEP; 5'-Dimethoxytrityl-2'-deoxyThymidine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite. Grade: ≥ 98%. CAS No. 98796-51-1. Molecular formula: C40H49N4O8P. Mole weight: 744.83. | |
| 5-O-DMT-thymidine 3'-H phosphonate triethylammonium salt | 5-O-DMT-thymidine 3'-H phosphonate triethylammonium salt, a pivotal ingredient in the dynamic field of biomedical science, emerges as an invaluable asset. Its multifaceted significance unfurls in the exploration of maladies etiology and the medley of therapeutic interventions. Expertly harnessed within scholarly interrogations, this compound illuminates the enigmatic realm of nucleotide analogues, unraveling the intricate tapestry governing DNA replication and restorative mechanisms. Veritably transcending boundaries, it assumes a decisive role in the innovative arena of antiviral drug fabrication, facilitating an in-depth comprehension of viral replications. Molecular formula: C37H48N3O9P. Mole weight: 709.77. | |
| 5'-O-DMT-thymidine-3'-lcaa-CPG | 5'-O-DMT-thymidine-3'-lcaa-CPG, an essential modified nucleotide, has garnered tremendous interest in the realm of biomedical research. Its purpose lies in the synthesis of oligonucleotides, granting researchers an unparalleled advantage in their studies. These resulting oligonucleotide conjugates play a pivotal role in the development of groundbreaking drug delivery systems, exhibiting immense potential as therapeutic agents targeting a plethora of diseases, including the infamous cancer and insidious viral infections. Synonyms: DMT-T-lcaa-CPG. | |
| 5'-O-DMT-thymidine 3'-Me phosphonamidite | 5'-O-DMT-thymidine 3'-Me phosphonamidite, a pivotal compound utilized in the synthesis of modified oligonucleotides, holds immense significance within the realm of biomedical research. Its frequent application in the pursuit of therapeutics directed towards drug-resistant viral infections, including hepatitis B and HIV, showcases its indispensability. Furthermore, this product serves as a fundamental asset in the progression of drug discovery and the extensive molecular biology investigations targeting these afflictions. Synonyms: 5'-O-DMT-D-thymidine 3'-Me phosphonamidite; 5'-(4,4'-Dimethoxytrityl)-thymidine, 3'-[methyl-(N,N-diisopropyl)]-phosphonamidite. Molecular formula: C38H48N3O7P. Mole weight: 689.78. | |
| 5'-O-DMT-thymidine 3'-Me phosphoramidite | 5'-O-DMT-thymidine 3'-Me phosphoramidite is a vital component in biomedical research for synthesizing modified DNA and RNA molecules. It is used to introduce a methyl group at the 3'-end of thymidine during solid-phase synthesis. This modified phosphoramidite enables the creation of customized nucleic acids for targeted drug delivery, gene therapy, and studying DNA-protein interactions. With its high purity and compatibility with automated synthesizers, it serves as an essential tool for advancing therapeutic developments and understanding genetic mechanisms. Synonyms: dT-Me Phosphoramidite; 5'-(4,4'-Dimethoxytrityl)-thymidine, 3'-[methyl-(N,N-diisopropyl)]-phosphoramidite. Molecular formula: C38H48N3O8P. Mole weight: 705.78. | |
| 5'-O-Dmt-thymidine 3'-o-succinate triethylammonium salt | 5'-O-Dmt-thymidine 3'-o-succinate triethylammonium salt is an influential nucleoside analogue extensively utilized in the biomedical research community, exhibiting immense potential for the investigation of intricate genetic ailments, including cancer, by virtue of its ability to impede DNA and RNA enhancement. Synonyms: 5'-O-(4,4'-dimethoxytrityl)-thymidine-3'-O-succinic acid triethylammonium salt. Grade: ≥98.0%. CAS No. 402944-22-3. Molecular formula: C43H51N3O10. Mole weight: 769.888. | |
| 5'-O-DMT-thymidine-3'-O-succinic acid | 5'-O-DMT-thymidine-3'-O-succinic acid, an indispensable compound extensively employed in the biomedical sector for versatile applications, exhibits its profound significance. Functioning as a pivotal precursor in antiviral drug synthesis, it selectively combats RNA and DNA viruses. Additionally, it remarkably contributes to the advancement of pharmaceuticals dedicated to the treatment of HIV, hepatitis, and cancer. Synonyms: 5'-O-(4,4'-Dimethoxytrityl)-thymidine-3'-O-succinic acid; 5'-O-(p,p'-Dimethoxytrityl)thymidine 3'-(hydrogen succinate). Grade: ≥ 99% (HPLC). CAS No. 74405-40-6. Molecular formula: C35H36N2O10. Mole weight: 644.67. | |
| 5'-O-DMT-thymidine 3'-Q Linker CPG | 5'-O-DMT-thymidine 3'-Q Linker CPG is a versatile product extensively used in the biomedical industry. Acting as a crucial component for solid-phase synthesis, it enables the synthesis of customized oligonucleotides, helping to study and develop therapeutic interventions for various diseases. Additionally, this linker CPG plays a vital role in drug discovery by facilitating the attachment of targeted molecules to nucleic acids, allowing for targeted drug delivery and enhanced treatment efficacy. | |
| 5'-O-DMT-thymidine 3'-succinyl | 5'-O-DMT-thymidine 3'-succinyl, an essential biomedicine, exhibits remarkable efficacy in alleviating a wide range of afflictions. Through its potent nucleoside analog properties, it flawlessly impedes viral replication, thereby assuming a pivotal role in the realm of antiviral therapies. Furthermore, this exceptional compound assumes utmost importance in DNA synthesis and repair, offering respite to those grappling with DNA-related maladies. | |
| 5'-O-DMT-thymidine-3'-succinyl CPG | 5'-O-DMT-thymidine-3'-succinyl CPG. | |
| 5'-O-DMT-thymidine 3'-thiophosphoramidite | 5'-O-DMT-thymidine 3'-thiophosphoramidite, a highly indispensable reagent employed in numerous biomedical applications, has the capability to confer augmented stability and safeguard the resultant sequences against degradation by nucleases. Its employment facilitates the precise introduction of 5'-O-DMT-thymidine into the oligonucleotide chain, thereby enabling focused therapeutic interventions for drug administration, gene suppression, and pathological condition detection. Synonyms: 5'-Dimethoxytrityl-2'-deoxythymidine 3'-[(B-thiobenzoylethyl)-(1-pyrrolidinyl)]-thiophosphoramidite; dT-Thiophosphoramidite. Grade: 90%. Molecular formula: C44H48N3O8PS2. Mole weight: 841.97. | |
| 5'-O-DMT-uridine | It is used for nucleoside modification and RNA synthesis. Synonyms: 5'-DMT Uridine; 5'-O-DMT uridine; 5'-O-(4,4'-Dimethyltrityl)uridine; 5'-O-DMT-D-uridine; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]uridine; 1-((2R,3R,4S,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3,4-dihydroxytetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione. Grade: ≥98% by HPLC. CAS No. 81246-79-9. Molecular formula: C30H30N2O8. Mole weight: 546.57. | |
| 5'-O-DMT-uridine 3'-CE phosphoramidite | 5'-O-DMT-uridine 3'-CE phosphoramidite, a pivotal compound employed in the realm of biomedical research and pharmaceutical advancement, stands as a vital cog in the synthesis of nucleotide analogs. By serving as a foundational unit, it facilitates the treatment of divergent ailments such as viral infections, cancer, and genetic disorders. Treading upon the path of nucleic acid synthesis, this product assumes a paramount stance in the augmentation of innovative therapeutic approaches within the realm of biomedicine. Synonyms: 5'-O-[Bis(4-methoxyphenyl)?phenylmethyl]?-uridine 3'-[2-cyanoethyl N,?N-bis(1-methylethyl)?phosphoramidite]. CAS No. 951777-44-9. Molecular formula: C39H47N4O9P. Mole weight: 746.79. | |
| 5'-O-DMT-uridine 3'-succinyl CPG | 5'-O-DMT-uridine 3'-succinyl CPG, a profoundly significant reagent within the biomedical field, serves as a catalyst for the synthesis of intricate oligonucleotides. Demonstrating its versatility, this compound finds wide-ranging applications in academic research, primarily within nucleic acid chemistry. | |
| 5-OH-dU-CE Phosphoramidite | 5-OH-dU-CE Phosphoramidite is an indispensable recompound within the realm of compound assuming a pivotal function in the research and development of altered nucleosides, thereby facilitating DNA/RNA investigations. It holds particular significance in the formulation of oligonucleotides, intended for diagnostics and therapeutics relating to hereditary afflictions or viral infestations. Synonyms: 5'-Dimethoxytrityl-5-O-Acetyl-2'-deoxyUridine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite. Grade: 95%. CAS No. 197229-19-9. Molecular formula: C41H49N4O10P. Mole weight: 788.83. | |
| 5-O-Lauryl-α-D-xylofuranose | 5-O-Lauryl-α-D-xylofuranose is a remarkable compound brandishing antiviral properties, used for the research of quell select viral aggressors. Synonyms: α-D-Xylofuranose, 5-dodecanoate; 5-O-Lauryl-D-xylofuranose. CAS No. 176793-21-8. Molecular formula: C17H32O6. Mole weight: 332.43. | |
| 5'-O-Levulinoylthymidine | 5'-O-Levulinoylthymidine is a derivative of thymidine, acting as a quintessential investigative instrument for scrutinizing the intricate mechanisms governing DNA research and rectification. Its utilization transcends these boundaries and extends towards facilitating developments in anti-cancer therapeutics and addressing maladies linked to DNA aberrations. Synonyms: 5'-O-Levulinoyl-D-thymidine. Grade: ≥ 98% (HPLC). CAS No. 440327-46-8. Molecular formula: C15H20N2O7. Mole weight: 340.33. | |
| 5'-O-Levulinoylthymidine 3'-CE phosphoramidite | 5'-O-Levulinoylthymidine 3'-CE phosphoramidite, an indispensable asset harnessed within the ever-evolving realms of the biomedical sector, emanates a profound influence upon the synthesis of tailored oligonucleotides. Reverberating as a catalyst for innovation, its innate ability to bestow a 5'-O-levulinoyl modification, combined with its role as a safeguarding entity during solid-phase synthesis, elicits transformative outcomes. Unveiling an extensive repertoire, this wondrous creation orchestrates a symphony of advancements in targeted drug delivery, gene therapy, and the diagnostic landscape. Synonyms: ((2R,3S,5R)-3-(((2-Cyanoethoxy)(diisopropylamino)phosphanyl)oxy)-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl 4-oxopentanoate. CAS No. 581076-14-4. Molecular formula: C24H37N4O8P. Mole weight: 540.55. | |
| 5'-OMe-dT-CE Phosphoramidite | 5'-OMe-dT-CE Phosphoramidite is a pivotal component in the research and development of customized oligonucleotides. Renowned for its unparalleled resilience and remarkable integration efficiency, 5'-OMe-dT-CE Phosphoramidite finds extensive utilization in the development of antiviral medication and gene therapeutics. Synonyms: 5'-O-methyl-2'-deoxyThymidine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; 5'-OMe-dT-CEP. Grade: 95%. CAS No. 149681-62-9. Molecular formula: C20H33N4O6P. Mole weight: 456.48. | |
| 5'-O-Methoxytrityluridine 3'-CE phosphoramidite | 5'-O-Methoxytrityluridine 3'-CE phosphoramidite is an exceedingly intricate chemical, often employed in the creation of synthetic DNA and RNA. It plays a critical role in oligonucleotide fusion techniques, protecting the sensitive nucleotide bonds during synthesis. The proficiency exhibited by this product extends to cancer diagnoses, particularly in cases of colorectal and lung cancer, via the employment of diagnostic assays. Synonyms: 5'-O-Methoxytrityl-D-uridine 3'-CE phosphoramidite. Molecular formula: C39H47N4O8P. Mole weight: 730.81. | |
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