BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
H-Gly-Pro-Gly-NH2 inhibits HIV-1 replication through its metabolite α-hydroxyglycineamide. It increases the antiviral activity of zidovudine and ritonavir. Synonyms: GPG-NH2; glycyl-L-prolyl-glycinamide; Glycinamide, glycyl-L-prolyl-; Glycyl-prolyl-glycyl amide; (2S)-1-(2-amino-1-oxoethyl)-N-(2-amino-2-oxoethyl)-2-pyrrolidinecarboxamide. Grades: ≥95% by HPLC. CAS No. 141497-12-3. Molecular formula: C9H16N4O3. Mole weight: 228.25.
Histidylphenylalanine is a competitive inhibitor of histidine decarboxylase. Synonyms: Histidylphenylalanine; His-phe; HF dipeptide; Histidine Phenylalanine dipeptide; L-Histidinyl-L-Phenylalanine. CAS No. 16874-81-0. Molecular formula: C15H18N4O3. Mole weight: 302.33.
H-His-Trp-OH
The dipeptide Trp-His inhibits the development of atherosclerosis onsets in ApoE -/- mice. Synonyms: His-Trp; L-histidyl-L-tryptophan; Histidinyl-Tryptophan; HW dipeptide; Histidine Tryptophan dipeptide. CAS No. 23403-90-9. Molecular formula: C17H19N5O3. Mole weight: 341.36.
HHV-2 Envelope Glycoprotein G (552-574)
HHV-2 Envelope Glycoprotein G (552-574) is the immunodominant region of mature glycoprotein G (gG-2) of herpes simplex virus type 2 (HSV-2). Synonyms: H-Pro-Pro-Pro-Pro-Glu-His-Arg-Gly-Gly-Pro-Glu-Glu-Phe-Glu-Gly-Ala-Gly-Asp-Gly-Glu-Pro-Pro-Glu-OH; L-Glutamic acid, L-prolyl-L-prolyl-L-prolyl-L-prolyl-L-α-glutamyl-L-histidyl-L-arginylglycylglycyl-L-prolyl-L-α-glutamyl-L-α-glutamyl-L-phenylalanyl-L-α-glutamylglycyl-L-alanylglycyl-L-α-aspartylglycyl-L-α-glutamyl-L-prolyl-L-prolyl-. Grades: ≥95%. CAS No. 2022956-63-2. Molecular formula: C103H146N28O38. Mole weight: 2384.46.
Hiascic acid
It is a tridepside isolated from lichens. Synonyms: 2-Hydroxy-6-methyl-4-[(3,4,6-trihydroxy-2-methylbenzoyl)oxy]benzoic acid 4-carboxy-3-hydroxy-5-methylphenyl ester; Hiascinsaeure; Hiasic acid; Benzoic acid, 2-hydroxy-6-methyl-4-[(3,4,6-trihydroxy-2-methylbenzoyl)oxy]-, 4-carboxy-3-hydroxy-5-methylphenyl ester. Grades: 98%. CAS No. 537-07-5. Molecular formula: C24H20O11. Mole weight: 484.41.
Hidrosmin Impurity
Cas No. 120250-44-4.
Hierridin
Hierridin is a substance obtained from the lichen Ramalina hierrensis. CAS No. 142382-20-5. Molecular formula: C29H52O3. Mole weight: 448.72.
H-Ile-Lys-Val-Ala-Val-OH
H-Ile-Lys-Val-Ala-Val-OH, the laminin core domain, mediates cell adhesion and is often used in surface modifications to improve biocompatibility. In particular, it stimulates the attachment and growth of neural stem cells. Synonyms: Laminin α-1 Chain (2099-2103) (human); L-isoleucyl-L-lysyl-L-valyl-L-alanyl-L-valine; H-IKVAV-OH; N-(N-(N-(N(2)-L-Isoleucyl-L-lysyl)-L-valyl)-L-alanyl)-L-valine. Grades: ≥95%. CAS No. 131167-89-0. Molecular formula: C25H48N6O6. Mole weight: 528.69.
Himandridine
Himandridine is a piperidine alkaloid isolated from Galbulimia sp. Grades: >95% by HPLC. CAS No. 15521-76-3. Molecular formula: C30H37NO7. Mole weight: 523.62.
Himbadine
Hibatidine is a piperidine alkaloid isolated from Galbulimima sp. Grades: >95% by HPLC. CAS No. 24932-15-8. Molecular formula: C21H31NO2. Mole weight: 329.48.
Himbosine
Himbosine is an alkaloid isolated from Galbulimima sp. Grades: >95% by HPLC. CAS No. 15448-14-3. Molecular formula: C35H41NO10. Mole weight: 635.71.
Himgaline
Himgaline is an alkaloid isolated from Galbulimima belgraveana. Grades: >95% by HPLC. CAS No. 16585-08-3. Molecular formula: C20H31NO2. Mole weight: 317.47.
Hippuryl-L-arginine is a substrate for carboxypeptidase B and carboxypeptidase N. Synonyms: Hippuryl-Arg; N-(Benzenecarbonyl)glycyl-L-Arginine; N2-(N-Benzoylglycyl)-L-arginine; L-Arginine,N-benzoylglycyl-. CAS No. 744-46-7. Molecular formula: C15H21N5O4. Mole weight: 335.36.
Hippuryl-L-lysine
Hippuryl-L-lysine is a substrate for carboxypeptidase B and carboxypeptidase N. Synonyms: Hippuryl-Lys-OH; Bz-GK-OH; L-Lysine,N-benzoylglycyl-; (S)-6-Amino-2-(2-benzamidoacetamido)hexanoic acid. CAS No. 740-63-6. Molecular formula: C15H21N3O4. Mole weight: 307.34.
Hippuryl-L-phenylalanine
Hippuryl-L-phenylalanine is used as a substrate for the determination of carboxypeptidase A and mast cell carboxypeptidase activities. Synonyms: (S)-2-(2-Benzamidoacetamido)-3-phenylpropanoic acid; Benzoyl-Gly-Phe; Hippuryl-Phe-OH; Bz-GF-OH. Grades: >99%. CAS No. 744-59-2. Molecular formula: C18H18N2O4. Mole weight: 326.36.
Hippuryl-Phe-Arg-OH
Hippuryl-Phe-Arg-OH is used as a substrate for angiotensin I-converting enzyme and for dipeptidyl carboxypeptidase. Synonyms: Hippuryl-phenylalanyl-arginine; Bz-GFR-OH. CAS No. 73167-83-6. Molecular formula: C24H30N6O5. Mole weight: 482.53.
His-Cys-Lys-Phe-Trp-Trp
His-Cys-Lys-Phe-Trp-Trp inhibits HIV-1 integrase (IN)-mediated 3'-processing and integration of HIV DNA. Synonyms: H-His-Cys-Lys-Phe-Trp-Trp-OH; HIV Integrase Protein Inhibitor(1); L-Tryptophan,l-histidyl-L-cysteinyl-L-Lysyl-L-phenylalanyl-l-tryptophyl-. CAS No. 172546-75-7. Molecular formula: C46H55N11O7S. Mole weight: 906.06.
His-Glu
Histidyl-glutamate is a dipeptide composed of histidine and glutamic acid. It is an incomplete breakdown product of protein digestion or protein catabolism. Synonyms: histidylglutamic acid; HE dipeptide; Histidinyl-Glutamate; L-His-L-Glu; Histidine Glutamate dipeptide. Grades: >98%. CAS No. 53634-28-9. Molecular formula: C11H16N4O5. Mole weight: 284.27.
Hispidalin, a bioactive peptide purified from the seeds of the medicinal plant B. hispida, has broad and potent inhibition against a variety of human bacterial and fungal pathogens. Synonyms: H-Ser-Asp-Tyr-Leu-Asn-Asn-Asn-Pro-Leu-Phe-Pro-Arg-Tyr-Asp-Ile-Gly-Asn-Val-Glu-Leu-Ser-Thr-Ala-Tyr-Arg-Ser-Phe-Ala-Asn-Gln-Lys-Ala-Pro-Gly-Arg-Leu-Asn-Gln-Asn-Trp-Ala-Leu-Thr-Ala-Asp-Tyr-Thr-Tyr-Arg-OH. Grades: ≥95%. CAS No. 2243219-67-0. Molecular formula: C255H378N72O78. Mole weight: 5700.25.
Histatin 5 acetate
Histatin 5, a human salivary peptide, has been shown to inhibit the activity of the host matrix metalloproteinases MMP-2 and MMP-9 with IC50s of 0.57 and 0.25 μM, respectively. Synonyms: H-Asp-Ser-His-Ala-Lys-Arg-His-His-Gly-Tyr-Lys-Arg-Lys-Phe-His-Glu-Lys-His-His-Ser-His-Arg-Gly-Tyr-OH.CH3CO2H; L-α-Aspartyl-L-seryl-L-histidyl-L-alanyl-L-lysyl-L-arginyl-L-histidyl-L-histidylglycyl-L-tyrosyl-L-lysyl-L-arginyl-L-lysyl-L-phenylalanyl-L-histidyl-L-α-glutamyl-L-lysyl-L-histidyl-L-histidyl-L-seryl-L-histidyl-L-arginylglycyl-L-tyrosine acetate salt; Human histatin 5 acetate salt; Peptide F-A (human parotid saliva) acetate salt. Grades: ≥95%. Molecular formula: C135H199N51O35. Mole weight: 3096.35.
Histidyl-asparagine
Histidyl-asparagine is a dipeptide composed of histidine and asparagine. CAS No. 158691-82-8. Molecular formula: C10H15N5O4. Mole weight: 269.26.
Histidyl-glutamine
Histidyl-glutamine is a dipeptide composed of histidine and glutamine. Synonyms: L-Histidyl-L-glutamine; His-Gln. CAS No. 224638-13-5. Molecular formula: C11H17N5O4. Mole weight: 283.28.
Histidyl-isoleucine
Histidyl-isoleucine is a peptide which functions as a hormone. Synonyms: L-histidyl-L-isoleucine; His-Ile; HI dipeptide. CAS No. 129050-48-2. Molecular formula: C12H20N4O3. Mole weight: 268.31.
Histone H3 (21-44) is a histone fragment that is used as a substrate for the protein arginine methyltransferase PRMT4. Synonyms: H3 (21-44); H-Ala-Thr-Lys-Ala-Ala-Arg-Lys-Ser-Ala-Pro-Ala-Thr-Gly-Gly-Val-Lys-Lys-Pro-His-Arg-Tyr-Arg-Pro-Gly-OH; L-Alanyl-L-threonyl-L-lysyl-L-alanyl-L-alanyl-L-arginyl-L-lysyl-L-seryl-L-alanyl-L-prolyl-L-alanyl-L-threonylglycylglycyl-L-valyl-L-lysyl-L-lysyl-L-prolyl-L-histidyl-L-arginyl-L-tyrosyl-L-arginyl-L-prolylglycine. Grades: ≥95%. CAS No. 1373516-71-2. Molecular formula: C109H185N39O29. Mole weight: 2505.91.
Hitachimycin
Hitachimycin is a macrolide antibiotic produced by Streptomyces No. KG-2245. It can inhibit tumor cell growth and antiprotozoal effects. Synonyms: Stubomycin. Grades: 95%. CAS No. 77642-19-4. Molecular formula: C29H35NO5. Mole weight: 477.59.
HIV Protease Substrate VI is a sensitive chromogenic substrate for both HIV-1 and HIV-2 proteases. Synonyms: H-Arg-Val-Nle-p-nitro-Phe-Glu-Ala-Nle-NH2; L-arginyl-L-valyl-L-norleucyl-4-nitro-L-phenylalanyl-L-alpha-glutamyl-L-alanyl-L-norleucinamide; L-Norleucinamide, L-arginyl-L-valyl-L-norleucyl-4-nitro-L-phenylalanyl-L-α-glutamyl-L-alanyl-. Grades: ≥95%. CAS No. 130877-92-8. Molecular formula: C40H66N12O11. Mole weight: 891.04.
H-Leu-Gly-Leu-Leu-Leu-Arg-His-Leu-Arg-His-His-Ser-Asn-Leu-Leu-Ala-Asn-Ile-OH, the peptide sequence B18 derived from membrane-associated sea urchin sperm protein-binding proteins, triggers fusion between lipid vesicles. It has many similarities with viral fusion peptides. Grades: ≥95%. CAS No. 222557-92-8. Molecular formula: C94H160N32O22. Mole weight: 2090.48.
H-Lys(Abz)-Pro-Pro-pNA is an internally quenched fluorogenic (FRET) substrate. CAS No. 219138-18-8. Molecular formula: C29H37N7O6. Mole weight: 579.65.
H-Lys-Ala-4MβNA 2 HCl
It is a specific fluorogenic substrate for dipeptidyl peptidase II (DPP II). Synonyms: Lys-Ala 4-methoxy-beta-naphthylamide dihydrochloride. Grades: 95%. CAS No. 118357-26-9. Molecular formula: C20H30Cl2N4O3. Mole weight: 445.38.
H-Lys-Ala-pNA 2HCl
H-Lys-Ala-pNA 2HCl, a chromogenic substrate for dipeptidyl aminopeptidase II (DPPII), is cleaved from Aspergillus fumigatus by dipeptidyl peptidase V (DPP V). Synonyms: KA-pNA dihydrochloride; L-Lysyl-N-(4-nitrophenyl)-L-alaninamide dihydrochloride; L-Alaninamide, L-lysyl-N-(4-nitrophenyl)-, hydrochloride (1:2). Grades: ≥95%. CAS No. 390366-87-7. Molecular formula: C15H23N5O4.2HCl. Mole weight: 410.30.
Nε,Nε,Nε-Trimethyllysine hydrochloride is a non-protein amino acid active in the biosynthesis of carnitine. Synonyms: Lys(Me)3-OH Chloride; (S)-5-Amino-5-carboxy-N,N,N-trimethylpentan-1-aminium chloride; Nε,Nε,Nε-Trimethyllysine hydrochloride. CAS No. 55528-53-5. Molecular formula: C9H21ClN2O2. Mole weight: 224.73.
H-Lys-Phe-Glu-Arg-Gln-OH
H-Lys-Phe-Glu-Arg-Gln-OH plays a broad role in targeting protein-enhanced degradation. Synonyms: L-Glutamine, L-lysyl-L-phenylalanyl-L-α-glutamyl-L-arginyl-; H-KFERQ-OH; L-lysyl-L-phenylalanyl-L-alpha-glutamyl-L-arginyl-L-glutamine. Grades: ≥95%. CAS No. 115084-19-0. Molecular formula: C31H50N10O9. Mole weight: 706.79.
H-Lys-Pro-OH
H-Lys-Pro-OH has the potential as a very promising healing agent in ulcer therapy. Synonyms: Lysylproline; Lys-pro; Lysyl-Proline; L-lysyl-L-proline; KP dipeptide; Lysine Proline dipeptide; L-Proline, L-lysyl-. CAS No. 52766-27-5. Molecular formula: C11H21N3O3. Mole weight: 243.30.
H-Lys-Tyr-Lys-OH
H-Lys-Tyr-Lys-OH can induce nicks at apurinic/apyrimidinic sites in circular DNA. Synonyms: Lysyl-tyrosyl-lysine; L-Lysine, N2-(N-L-lysyl-L-tyrosyl)-; (S)-6-amino-2-((S)-2-((S)-2,6-diaminohexanamido)-3-(4-hydroxyphenyl)propanamido)hexanoic acid. Grades: ≥97%. CAS No. 35193-18-1. Molecular formula: C21H35N5O5. Mole weight: 437.53.
H-Met-D-Met-OH
Cas No. 89680-18-2. Molecular formula: C10H20N2O3S2. Mole weight: 280.41.
H-Met-Gly-Pro-AMC HCl
H-Met-Gly-Pro-AMC HCl is a fluorogenic substrate for methionine aminopeptidases 1D and 2. Synonyms: MGP-AMC HCl; L-Methionylglycyl-N-(4-methyl-2-oxo-2H-chromen-7-yl)-L-prolinamide hydrochloride (1:1); L-Prolinamide, L-methionylglycyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-, hydrochloride (1:1). Grades: ≥95% by HPLC. CAS No. 1926163-53-2. Molecular formula: C22H28N4O5S.HCl. Mole weight: 497.01.
H-Met-Trp-OH TFA salt is an incomplete breakdown product of protein digestion or protein catabolism. It is a non-competitive inhibitor of angiotensin-1 converting enzyme (ACE). Synonyms: H-Met-Trp-OH Trifluoroacetate salt; L-methionyl-L-tryptophan trifluoroacetic acid; (S)-2-((S)-2-Amino-4-(methylthio)butanamido)-3-(1H-indol-3-yl)propanoic acid compound with 2,2,2-trifluoroacetic acid (1:1). Molecular formula: C16H21N3O3S.C2HF3O2. Mole weight: 449.45.
Hodgkinsine
Hodgkinsine is a pyrrolidinoindoline alkaloid isolated from P. colorata. Grades: >95% by HPLC. CAS No. 18210-71-4. Molecular formula: C33H38N6. Mole weight: 518.71.
Hodgkinsine trimethyl triiodide
Hodgkinsine trimethyl is a trimethylated form of hodgkinsine. Grades: >95% by HPLC. Molecular formula: C36H47N6.I3. Mole weight: 944.5.
Cas No. 13416-66-5. Molecular formula: C30H52O2. Mole weight: 444.73.
Hortein
Hortein is a polyketide fungal metabolite isolated from H. werneckii. Grades: >95% by HPLC. CAS No. 346610-88-6. Molecular formula: C20H12O6. Mole weight: 348.31.
H-p-Chloro-Phe-D-Cys-β-(3-pyridyl)-Ala-D-Trp-N-Me-Lys-Thr-Cys-2-Nal-NH2 is the somatostatin-14 analog, with a high affinity of 5.98 nM for somatostatin receptor subtype 5 (SST5) (1.4 nM for somatostatin-14). It is the first antagonist with high affinity for SST5. Synonyms: H-p-Chloro-Phe-D-Cys-β-(3-pyridyl)-Ala-D-Trp-N-Me-Lys-Thr-Cys-2-Nal-NH2 (Disulfide bridge: Cys2-Cys7); 4-chloro-L-phenylalanyl-D-cysteinyl-3-(3-pyridyl)-L-alanyl-D-tryptophyl-N-methyl-L-lysyl-L-threonyl-L-cysteinyl-3-(2-naphthyl)-L-alaninamide (2->7)-disulfide; H-Phe(4-Cl)-D-Cys(1)-3Pal-D-Trp-N(Me)Lys-Thr-Cys(1)-2Nal-NH2; PRL-3195; 4-Cpa-cyclo(D-Cys-3-Pal-D-Trp-MeLys-Thr-Cys)-2-Nal-NH2. Grades: ≥90%. CAS No. 341519-04-8. Molecular formula: C58H69ClN12O9S2. Mole weight: 1177.83.
H-Phe-Gly-His-p-nitro-Phe-Phe-Ala-Phe-OMe
A good substrate for pepsin which is also cleaved by cathepsin D. Synonyms: Phe-Gly-His-Phe(NO2)-Phe-Ala-Phe-OMe; Methyl L-phenylalanylglycyl-L-histidyl-4-nitro-L-phenylalanyl-L-phenylalanyl-L-alanyl-L-phenylalaninate. CAS No. 50572-79-7. Molecular formula: C48H54N10O10. Mole weight: 931.00.
H-Phe-Met-Arg-Phe-NH2
H-Phe-Met-Arg-Phe-NH2 is a molluscan neuropeptide isolated from the ganglia of Macrocallista nimbosa. Synonyms: Fmrfamide; FMRF amide; (S)-N-((S)-1-Amino-1-oxo-3-phenylpropan-2-yl)-2-((S)-2-((S)-2-amino-3-phenylpropanamido)-4-(methylthio)butanamido)-5-guanidinopentanamide; Molluscan Cardioexcitatory Neuropeptide. CAS No. 152165-14-5. Molecular formula: C29H42N8O4S. Mole weight: 598.76.
Prolyl-Asparagine is a dipeptide composed of proline and asparagine. Synonyms: Pro-Asn; H-Pro-Asn-OH; L-prolyl-L-asparagine. CAS No. 107856-82-6. Molecular formula: C9H15N3O4. Mole weight: 229.23.