BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Dodecanoyl D-sucrose | Dodecanoyl D-sucrose is an extensively utilized biomedical product, renowned for its formidable antiviral and antibacterial attributes. This compound effectively studys viral and bacterial infections. Moreover, its commendable prowess in augmenting drug solubility and stability has rendered it indispensable in the development of revolutionary pharmaceutical carriers. Synonyms: n-Monododecanoate a-D-glucopyranoside; Sucrose monolaurate; α-D-Glucopyranoside, β-D-fructofuranosyl, monododecanoate; Lauric acid, monoester with sucrose; Sucrose, laurate; Cane sugar monolaurate; Saccharose laurate; Saccharose monolaurate; SM1200; Sucrose lauric acid ester; Sucrose lauric acid monoester; Sucrose lauryl ester; Sucrose monododecanoate; Sucrose monolaurate; Sucrose monolauryl ester; Surfhope SE Cosme C 1216; Surfhope SE Pharma D 1216. CAS No. 25339-99-5. Molecular formula: C24H44O12. Mole weight: 524.60. |  |
| Dodecyl 2-acetamido-2-deoxy-b-D-glucopyranoside | Dodecyl 2-acetamido-2-deoxy-b-D-glucopyranoside is a vital compound used in the biomedical industry. It is commonly employed in research to study cell membrane structure and function. Additionally, it serves as a nonionic surfactant, aiding in the solubilization of membrane proteins, lipids, and carbohydrates. This versatile compound plays a crucial role in drug development, especially for treatments targeting diseases related to cell membranes and protein-lipid interactions. Synonyms: Dodecyl 2-(acetylamino)-2-deoxy-β-D-glucopyranoside; N-((2R,3R,4R,5S,6R)-2-(dodecyloxy)-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)acetamide. CAS No. 147025-06-7. Molecular formula: C20H39NO6. Mole weight: 389.53. | |
| Dodecyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-b-D-glucopyranoside | Dodecyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-b-D-glucopyranoside is a glucose-derived element unveiling remarkable antimicrobial attributes that warrant its application in antibiotic research. Its remarkable proficiency in restraining the proliferation of distinct bacterial and fungal strains tangibly. Synonyms: β-D-Glucopyranoside, dodecyl 2-(acetylamino)-2-deoxy-, 3,4,6-triacetate; (2R,3S,4R,5R,6R)-5-Acetamido-2-(acetoxymethyl)-6-(dodecyloxy)tetrahydro-2H-pyran-3,4-diyl diacetate; Dodecyl 2-(acetylamino)-2-deoxy-3,4,6-triacetate β-D-Glucopyranoside. CAS No. 211567-22-5. Molecular formula: C26H45NO9. Mole weight: 515.64. | |
| Dodecyl 2-(N,N-dimethylamino)propionate | Dodecyl 2-(N,N-dimethylamino)propionate, a chemical enhancer, is used for in vitro transdermal and transbuccal delivery of lidocaine-HCl (LHCl), nicotine hydrogen tartrate (NHT), and diltiazem-HCl (DHCl). Synonyms: Alanine, N,N-dimethyl-, dodecyl ester; DDAIP; Dodecyl N,N-Dimethylalaninate; N,N-Dimethyl-, dodecyl ester alanine; N,N-Dimethylalanine dodecyl ester. Grade: ≥95%. CAS No. 224297-43-2. Molecular formula: C17H35NO2. Mole weight: 285.46. | |
| Dodecyl a-D-glucopyranoside | Dodecyl a-D-glucopyranoside is a compound product used as a non-ionic detergent and solubilizer in various applications. It is commonly utilized in the pharmaceutical industry for drug formulation, especially for enhancing the solubility and stability of hydrophobic drugs. Additionally, it finds applications in cell culture, membrane protein studies and crystallization. Synonyms: Dodecyl α-D-glucopyranoside; Glucopyranoside, dodecyl, α-D-; Dodecyl α-D-glucoside; Lauryl α-D-glucopyranoside; n-Dodecyl α-D-glucopyranoside; (2S,3R,4S,5S,6R)-2-(Dodecyloxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol. CAS No. 29980-16-3. Molecular formula: C18H36O6. Mole weight: 348.47. | |
| Dodecyl a-D-maltopyranoside | Dodecyl a-D-maltopyranoside is a non-ionic surfactant widely used for the solubilization, purification, and stabilization of membrane proteins. It is particularly effective in the extraction of non-covalently bound integral membrane proteins. Dodecyl a-D-maltopyranoside is also used in the production of vaccines and antibodies, and in various biomedical research applications. Synonyms: n-Dodecyl a-D-maltoside; Lauryl a-maltoside; Dodecyl 4-O-α-D-glucopyranosyl-α-D-glucopyranoside; Dodecyl α-D-maltoside; Lauryl α-D-maltopyranoside; n-Dodecyl α-D-maltoside; (2R,3R,4S,5S,6R)-2-(((2R,3S,4R,5R,6S)-6-(Dodecyloxy)-4,5-dihydroxy-2-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol. CAS No. 116183-64-3. Molecular formula: C24H46O11. Mole weight: 510.62. | |
| Dodecyl a-D-thiomannopyranoside | Dodecyl α-D-thiomannopyranoside is a biochemical product acting as a nonionic detergent to solubilize membrane proteins, facilitating their isolation and characterization. This compound finds applications in the study of various cellular processes and interactions, including membrane receptor functions, signal transduction pathways and enzyme activities. Its versatile nature makes it a valuable tool for investigating drug targets and disease mechanisms. Molecular formula: C18H36O5S. Mole weight: 364.54. | |
| Dodecyl b-D-cellobioside | Dodecyl b-D-cellobioside is a compound utilized in the biomedical industry exhibiting potential as an effective drug delivery system due to its surfactant properties. Synonyms: β-D-Glucopyranoside, dodecyl 4-O-β-D-glucopyranosyl-; Dodecyl 4-O-β-D-glucopyranosyl-β-D-glucopyranoside; Dodecyl β-D-cellobiopyranoside; Dodecyl beta-d-cellobioside. CAS No. 74513-19-2. Molecular formula: C24H46O11. Mole weight: 510.62. | |
| Dodecyl b-D-galactopyranoside | Dodecyl b-D-galactopyranoside is an extensively employed surfactant within the biomedical sector, whereby it amplifies the solubility and steadiness of hydrophobic proteins and diverse biomolecules. This particular compound demonstrates a remarkable capability in facilitating the extraction of membrane proteins with heightened efficacy, while simultaneously augmenting protein crystallization proficiency. Moreover, its utilization extends to drug delivery mechanisms, rendering it advantageous in the comprehensive analysis of multifarious ailments such as cancer, neurodegenerative disorders and infectious diseases. Synonyms: (2R,3R,4S,5R,6R)-2-(dodecyloxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol; Dodecyl β-D-galactopyranoside; Galactopyranoside, dodecyl, β-D-. CAS No. 102043-71-0. Molecular formula: C18H36O6. Mole weight: 348.48. | |
| Dodecyl b-D-glucopyranoside | Dodecyl b-D-glucopyranoside is a surfactant commonly used in the biomedical industry for various applications. It is utilized in drug formulation and gene delivery systems due to its ability to solubilize hydrophobic drugs. Additionally, it plays a crucial role in cell lysis, protein extraction, and enzyme stabilization. It is also employed in biochemistry and biotechnology research for the purification and analysis of glycoproteins and glycolipids. Synonyms: Dodecyl glucoside; n-Dodecyl b-D-glucopyranoside; Dodecyl β-D-glucopyranoside; Glucoside, dodecyl; AG 12; AG 12 (carbohydrate); BDDG; Dodecyl β-D-glucoside; n-Dodecyl β-D-glucopyranoside. CAS No. 59122-55-3. Molecular formula: C18H36O6. Mole weight: 348.47. | |
| Dodecyl b-D-thiomaltopyranoside | Dodecyl b-D-thiomaltopyranoside is a valuable compound widely used in the biomedicine industry. Known for its excellent solubility, it is commonly utilized as a nonionic detergent and surfactant in various biochemical and molecular biology applications. Synonyms: n-Dodecyl b-D-thiomaltoside; Dodecyl 4-O-(a-D-glucopyranosyl)-1-thio-b-D-glucopyranoside; Dodecyl 4-O-α-D-glucopyranosyl-1-thio-β-D-glucopyranoside; 1-S-Dodecyl β-D-thiomaltopyranoside; n-Dodecyl b-D-thiomaltopyranoside. CAS No. 148565-58-6. Molecular formula: C24H46O10S. Mole weight: 526.68. | |
| Dodecyl D-glucopyranoside | Dodecyl D-glucopyranoside. Synonyms: Lauryl D-glucopyranoside. CAS No. 27836-64-2. Molecular formula: C18H36O6. Mole weight: 348.47. | |
| Dodecylguanidine hydrochloride | Dodecylguanidine is used as an antibacterial agent and an antifungal agrochemical. Synonyms: Dodecylguanidine monohydrochloride; Metasol DGH; N-Dodecylguanidine hydrochloride. Grade: 95%. CAS No. 13590-97-1. Molecular formula: C13H30ClN3. Mole weight: 263.85. | |
| Dofequidar | Dofequidar, also known as MS-209, is a quinolone-derived sphingomyelin synthase inhibitor that blocks P-glycoprotein and multidrug resistance-associated protein-1, is under development by Schering for the potential treatment of multidrug resistant tumors. Dofequidar was found to sensitizes cancer stem-like side population cells to chemotherapeutic drugs by inhibiting ABCG2/BCRP-mediated drug export. Uses: Antineoplastic agents. Synonyms: Dofequidar. CAS No. 129716-58-1. Molecular formula: C30H31N3O3. Mole weight: 481.596. | |
| Dofequidar fumarate | Dofequidar fumarate, a quinoline derivative, is a multidrug resistance (MDR)-reversing quinoline derivative by inhibiting ABCB1/P-gp, ABCC1/MDR-associated protein 1, or both. It has potential to treat advanced and recurrent breast cancer and non-small lun. Synonyms: MS-209; MS 209; MS209. CAS No. 153653-30-6. Molecular formula: C34H35N3O7. Mole weight: 597.66. | |
| Dofetilide | Dofetilide is a selective potassium channel ((hERG)) blocker, used as a Class III antiarrhythmic drug. Synonyms: UK 68798; UK 68798; UK 68798; Dofetilide; Dofetilidum; Tikosyn. Grade: >98%. CAS No. 115256-11-6. Molecular formula: C19H27N3O5S2. Mole weight: 441.56. | |
| Dolasetron | Dolasetron, a pseudopelletierine derivative, is a 5-HT3 receptor antagonist that could be used to relieve the nausea and vomiting caused by chemotherapy. Synonyms: 1H-Indole-3-carboxylic acid, octahydro-3-oxo-2,6-methano-2H-quinolizin-8-yl ester, stereoisomer; 1H-Indole-3-carboxylic acid, octahydro-3-oxo-2,6-methano-2H-quinolizin-8-yl ester, (2α,6α,8α,9aβ)-; Anemet; MDL 73147. Grade: 95%. CAS No. 115956-12-2. Molecular formula: C19H20N2O3. Mole weight: 324.37. | |
| Dolasetron mesylate | The mesylate salt form of Dolasetron which is a pseudopelletierine derivative and could be used to relieve the nausea and vomiting caused by chemotherapy for behaving as a 5-HT3 receptor antagonist. Synonyms: Dolasetron methanesulfonate; Dolasetron mesilate. Grade: 98%. CAS No. 115956-13-3. Molecular formula: C19H20N2O3.CH4O3S. Mole weight: 420.48. | |
| Dolastatin 10 trifluoroacetate | Dolastatin 10 trifluoroacetate inhibits tubulin polymerization and induces tubulin aggregation in vitro. Synonyms: Dolastatin 10 trifluoroacetate; 2342568-65-2; EX-A8176; AKOS027470141; AKOS040745145; PD080063; Dolastatin 10 trifluoroacetate (110417-88-4 free base); (2S)-2-[[(2S)-2-(dimethylamino)-3-methylbutanoyl]amino]-N-[(3R,4S,5S)-3-methoxy-1-[(2S)-2-[(1R,2R)-1-methoxy-2-methyl-3-oxo-3-[[(1S)-2-phenyl-1-(1,3-thiazol-2-yl)ethyl]amino]propyl]pyrrolidin-1-yl]-5-methyl-1-oxoheptan-4-yl]-N,3-dimethylbutanamide; 2,2,2-trifluoroacetic acid; N,N-Dimethyl-L-valyl-N-[(1S,2R)-2-methoxy-4-[(2S)-2-[(1R,2R)-1-methoxy-2-methyl-3-oxo-3-[[(1S)-2-phenyl-1-(2-thiazol)ethyl]amino]propyl]-1-pyrrolidinyl]-1-[(1S)-1-methylpropyl]-4-oxobutyl]-N-methyl--valinamide trifluoroacetate. CAS No. 2342568-65-2. Molecular formula: C42H68N6O6S.CF3CO2H. Mole weight: 899.11. | |
| Dolastatin 15 | Dolastatin 15 (DLS 15), a depsipeptide derived from Dolabella auricularia, is a potent antimitotic agent structurally related to the antitubulin agent Dolastatin 10. Dolastatin 15 induces cell cycle arrest and apoptosis in multiple myeloma cells. Dolastatin 15 can be used as an ADC cytotoxin. Synonyms: DLS 15; (S)-1-((S)-2-benzyl-3-methoxy-5-oxo-2,5-dihydro-1H-pyrrol-1-yl)-3-methyl-1-oxobutan-2-yl N-dimethyl-L-valyl-L-valyl-N-methyl-L-valyl-L-prolyl-L-prolinate; L-Proline, N,N-dimethyl-L-valyl-L-valyl-N-methyl-L-valyl-L-prolyl-, (1S)-1-[[(2S)-2,5-dihydro-3-methoxy-5-oxo-2-(phenylmethyl)-1H-pyrrol-1-yl]carbonyl]-2-methylpropyl ester. Grade: ≥98%. CAS No. 123884-00-4. Molecular formula: C45H68N6O9. Mole weight: 837.06. | |
| Dolutegravir | Dolutegravir is a two-metal-binding HIV-1 integrase inhibitor with IC50 of 2.7 nM, with modest activity against raltegravir-resistant signature mutants Y143R, Q148K, N155H, and G140S/Q148H. It blocks the strand transfer step of the integration of the viral genome into the host cell (INSTI). Synonyms: GSK-1349572; GSK 1349572; GSK1349572; Tivicay. Grade: ≥98%. CAS No. 1051375-16-6. Molecular formula: C20H19F2N3O5. Mole weight: 419.38. | |
| Dolutegravir Impurity B | An impurity of Dolutegravir. Dolutegravir is an antiretroviral drug belonging to the integrase strand transfer inhibitor (INSTI) class. Synonyms: N-[(2,4-Difluorophenyl)methyl]-1,8-dihydro-9-hydroxy-2-(3-hydroxy-1-methylpropyl)-1,8-dioxo-2H-pyrido[1,2-a]pyrazine-7-carboxamide; Dolutegravir ring open impurity; N-(2,4-Difluorobenzyl)-9-hydroxy-2-(4-hydroxybutan-2-yl)-1,8-dioxo-1,8-dihydro-2H-pyrido[1,2-a]pyrazine-7-carboxamide. Grade: ≥95%. CAS No. 2374716-73-9. Molecular formula: C20H19F2N3O5. Mole weight: 419.38. | |
| Dolutegravir sodium | Dolutegravir sodium salt is a HIV integrase inhibitor(IC50= 2.7 nM), modest activity against raltegravir-resistant signature mutants Y143R, Q148K, N155H, and G140S/Q148H. Uses: Hiv integrase inhibitors. Synonyms: DTG; GSK1349572; GSK 1349572; GSK-1349572. Grade: >98%. CAS No. 1051375-19-9. Molecular formula: C20H18F2N3NaO5. Mole weight: 441.36. | |
| Domiphen Bromide | Domiphen bromide is a quaternary ammonium antiseptic with actions as a cationic surfactant. Uses: Anti-infective (topical). Synonyms: NSC-39415; NSC 39415; NSC39415. Grade: >98%. CAS No. 538-71-6. Molecular formula: C22H40NO.Br. Mole weight: 414.46. | |
| Domperidone Impurity | 1-(3-Chloropropyl)-1,3-dihydrobenzimidazol-2-one is a benzimidazole derivative used in the preparation of neuroleptic and antiallergic agents. Synonyms: 1-(3-Chloropropyl)-1,3-dihydro-2H-benzimidazol-2-one. Grade: > 95%. CAS No. 62780-89-6. Molecular formula: C10H11ClN2O. Mole weight: 210.66. | |
| Domperidone Impurity A | A metabolite of the gastrokinetic and antinauseant drug Domperidone. Synonyms: 5-Chloro-1-(4-piperidinyl)-2-benzimidazolidinone; Des[3-(2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)propyl] Domperidone; 4-(6-Chloro-1,2-dihydro-2-oxobenzo[d]imidazol-3-yl)piperidine; 5-Chloro-1-(4-piperidinyl)-1,3-dihydro-2H-benzimidazol-2-one; 5-Chloro-1-(p. Grade: > 95%. CAS No. 53786-28-0. Molecular formula: C12H14ClN3O. Mole weight: 251.71. | |
| Domperidone Impurity B | An impurity of the gastrokinetic and antinauseant drug Domperidone. Synonyms: 4-(6-Chloro-1,2-dihydro-2-oxobenzo[d]imidazol-3-yl)piperidine-1-carbaldehyde; 5-Chloro-1-(4-formylpiperidinyl)-1,3-dihydro-2H-benzimidazol-2-one; 5-Chloro-1-(4-formylpiperidinyl)-1H-benzimidazol-2(3H)-one. Grade: > 95%. CAS No. 1346598-11-5. Molecular formula: C13H14ClN3O2. Mole weight: 279.72. | |
| Domperidone Impurity C | An oxygenated metabolite of the gastrokinetic and antinauseant drug Domperidone. Synonyms: 5-Chloro-1-[1-[3-(2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)propyl]-1-oxido-4-piperidinyl]-1,3-dihydro-2H-benzimidazol-2-one; Domperidine Impurity C; 5-Chloro-1-[1-[3-[(2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)propyl]-4-piperidinyl]]-1,3-dihydro-2H-benzimidazo. Grade: > 95%. CAS No. 118435-03-3. Molecular formula: C22H24ClN5O3. Mole weight: 441.91. | |
| Domperidone Impurity D | An impurity of the gastrokinetic and antinauseant drug Domperidone. Synonyms: 5-Chloro-3-[3-(2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)propyl]-1-[1-[3-(2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)propyl]-4-piperidinyl]-1,3-dihydro-2H-benzimidazol-2-one. Grade: > 95%. CAS No. 1614255-34-3. Molecular formula: C32H34ClN7O3. Mole weight: 600.11. | |
| Domperidone Impurity E | An impurity of the gastrokinetic and antinauseant drug Domperidone. Synonyms: 3'-[3-(2,3-Dihydro-2-oxo-1H-benzimidazol-1-yl)propyl] Domperidone; 5-Chloro-1-[1-[3-[2,3-dihydro-2-oxo-3-[3-(2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)propyl]-1H-benzimidazol-1-yl]propyl]-4-piperidinyl]-1,3-dihydro-2H-benzimidazol-2-one. Grade: > 95%. CAS No. 1346602-50-3. Molecular formula: C32H34ClN7O3. Mole weight: 600.13. | |
| Domperidone Impurity F | An impurity of the gastrokinetic and antinauseant drug Domperidone. Synonyms: 3'-[4-(5-Chloro-2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)-1-piperidinyl]propyl Domperidine. Grade: > 95%. CAS No. 1391053-55-6. Molecular formula: C37H42Cl2N8O3. Mole weight: 717.69. | |
| Domperidone maleate | Domperidone maleate is the salt of Domperidone, which is a dopamine antagonist medication used to treat nausea and vomiting and certain gastrointestinal problems like gastroparesis (delayed gastric emptying). Uses: Antiemetics. Synonyms: 2H-Benzimidazol-2-one, 5-chloro-1-[1-[3-(2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)propyl]-4-piperidinyl]-1,3-dihydro-, (2Z)-2-butenedioate (1:x); 2H-Benzimidazol-2-one, 5-chloro-1-[1-[3-(2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)propyl]-4-piperidinyl]-1,3-dihydro-, (Z)-2-butenedioate (1:x); 5-chloro-1-(1-(3-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)propyl)piperidin-4-yl)-1,3-dihydro-2H-benzo[d]imidazol-2-one maleate (1:x). Grade: ≥95%. CAS No. 99497-03-7. Molecular formula: C22H24ClN5O2.xC4H4O4. Mole weight: 425.91 (free base). | |
| Domperidone monomaleate | Domperidone monomaleate is the salt of Domperidone, which is a dopamine antagonist medication used to treat nausea and vomiting and certain gastrointestinal problems like gastroparesis (delayed gastric emptying). Synonyms: 2H-Benzimidazol-2-one, 5-chloro-1-[1-[3-(2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)propyl]-4-piperidinyl]-1,3-dihydro-, (2Z)-2-butenedioate (1:1); 2H-Benzimidazol-2-one, 5-chloro-1-[1-[3-(2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)propyl]-4-piperidinyl]-1,3-dihydro-, (Z)-2-butenedioate (1:1); Domperidone maleate; 5-chloro-1-(1-(3-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)propyl)piperidin-4-yl)-1,3-dihydro-2H-benzo[d]imidazol-2-one maleate. Grade: 95%. CAS No. 83898-65-1. Molecular formula: C22H24ClN5O2.C4H4O4. Mole weight: 541.99. | |
| Donepezil | Donepezil, also called Aricept, a centrally acting reversible acetyl cholinesterase inhibitor that the FDA has also approved for the treatment of moderate to severe Alzheimer's disease. It readily crosses the blood-brain barrier to reduce the breakdown of acetylcholine by increasing the concentration of acetylcholine through reversible inhibition of its hydrolysis by acetylcholinesterase. Synonyms: 2,3-Dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-1H-inden-1-one; (±)-E 2020; 1-Benzyl-4-[(5,6-dimethoxy-1-oxoindan-2-yl)methyl]piperidine; Neuripezil; Tonizep; 2-((1-Benzylpiperidin-4-yl)methyl)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one; Aricept; HSDB 7743; HSDB7743; HSDB-7743; 1-benzyl-4-((5,6-dimethoxy-1-indanon)-2-yl)methylpiperidine hydrochloride; 2-((1-Benzylpiperidin-4-yl)methyl)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one; Eranz; Aricept ODT; donepezilo; donepezilum; CHEMBL502; donepezil hydrochloride; donepezilium oxalate trihydrate; E 2020; E-2020; E2020; 2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxyindan-1-one; (RS)-2-[(1-BENZYL-PIPERIDIN-4-YL)METHYL]-5,6-DIMETHOXYINDAN-1-ONE. Grade: > 98%. CAS No. 120014-06-4. Molecular formula: C24H29NO3. Mole weight: 379.49. | |
| Donepezil Alkene Pyridine N-Oxide | Donepezil Alkene Pyridine N-Oxide is an impurity of Donepezil, a medication for the treatment of Alzheimer's disease. Synonyms: 1H-Inden-1-one, 2,3-dihydro-5,6-dimethoxy-2-[(1-oxido-4-pyridinyl)methylene]-; 2,3-Dihydro-5,6-dimethoxy-2-[(1-oxido-4-pyridinyl)methylene]-1H-inden-1-one; 4-[(5,6-dimethoxy-1-indanon-2-ylidene)methyl]pyridine N-oxide; 4-((5,6-Dimethoxy-1-oxo-1H-inden-2(3H)-ylidene)methyl)pyridine 1-oxide. Grade: ≥95%. CAS No. 896134-06-8. Molecular formula: C17H15NO4. Mole weight: 297.31. | |
| Donepezil-D5 hydrochloride | One of the isotopic labelled form of donepezil, which is a cholinesterase inhibitor. Synonyms: 2,3-Dihydro-5,6-dimethoxy-2-[[1-((phenyl-d5)methyl)-4-piperidinyl]methyl]-1H-inden-1-one hydrochloride. Grade: ≥98% by HPLC; 98% atom D. Molecular formula: C24H24D5NO3.HCl. Mole weight: 420.99. | |
| Donepezil Didesmethyl Impurity | Donepezil Didesmethyl Impurity is an impurity of Donepezil, a medication for the treatment of Alzheimer's disease. Synonyms: 2-((1-Benzylpiperidin-4-yl)methyl)-5,6-dihydroxy-2,3-dihydro-1H-inden-1-one. CAS No. 220170-71-8. Molecular formula: C22H25NO3. Mole weight: 351.45. | |
| Donepezil EP Impurity C | Donepezil EP Impurity C is an impurity of Donepezil, a medication for the treatment of Alzheimer's disease. Synonyms: (R)-2-((S)-(1-Benzylpiperidin-4-yl)(hydroxy)methyl)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one. CAS No. 2452407-76-8. Molecular formula: C24H29NO4. Mole weight: 395.49. | |
| Donepezil EP Impurity G | Donepezil EP Impurity G is one of Donepezil impurities. Donepezil, a highly specific reversible acetylcholinesterase (AChE) inhibitor, is used to treat moderate to severe Alzheimer's disease. Synonyms: YT2G5HE97P. CAS No. 2452407-72-4. Molecular formula: C24H27NO3. Mole weight: 377.48. | |
| Donepezil hydrochloride monohydrate | Donepezil is a highly specific reversible acetylcholinesterase (AChE) inhibitor used to treat moderate to severe Alzheimer's disease. Synonyms: 2-((1-Benzylpiperidin-4-yl)methyl)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one hydrochloride hydrate; 1H-Inden-1-one, 2,3-dihydro-5,6-dimethoxy-2-((1-(phenylmethyl)-4-piperidinyl)methyl)-, hydrochloride, hydrate (1:1:1); 2,3-Dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-1H-inden-1-one hydrochloride hydrate. Grade: ≥95%. CAS No. 884740-09-4. Molecular formula: C24H29NO3.HCl.H2O. Mole weight: 433.97. | |
| Donepezil Impurity 14 | Donepezil Impurity 14 is one of Donepezil impurities. Donepezil, a highly specific reversible acetylcholinesterase (AChE) inhibitor, is used to treat moderate to severe Alzheimer's disease. Uses: A labelled impurity of donepezil (d531750); an intermediate as an anti-alzheimer's agent. Synonyms: 1-Benzyl-4-(5,6-dimethoxy-1-oxoindan-2-ylindenemethyl)piperidine; 2-((1-Benzylpiperidin-4-yl)methylene)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one; Donepezil related compound A; (E)-2-((1-benzylpiperidin-4-yl)methylene)-5,6-dimethoxyindan-1-one. Grade: > 95 %. CAS No. 120014-07-5. Molecular formula: C24H27NO3. Mole weight: 377.48. | |
| Donepezil Impurity 15 | Donepezil Impurity 15 is one of Donepezil impurities. Donepezil, a highly specific reversible acetylcholinesterase (AChE) inhibitor, is used to treat moderate to severe Alzheimer's disease. Molecular formula: C17H15NO4. Mole weight: 297.30. | |
| Donepezil Impurity 16 | Donepezil Impurity 16 is one of Donepezil impurities. Donepezil, a highly specific reversible acetylcholinesterase (AChE) inhibitor, is used to treat moderate to severe Alzheimer's disease. Molecular formula: C24H29NO3.HCl. Mole weight: 415.95. | |
| Donepezil Impurity 17 HCl | Donepezil Impurity 17 HCl is one of Donepezil impurities. Donepezil, a highly specific reversible acetylcholinesterase (AChE) inhibitor, is used to treat moderate to severe Alzheimer's disease. CAS No. 2217617-87-1. Molecular formula: C24H29NO5.HCl. Mole weight: 447.95. | |
| Donepezil Impurity 2 | Donepezil impurity. Synonyms: 5,6-Dimethoxy-1H-Indene-1,3(2H)-dione; 5,6-Dimethoxyindane-1,3-dione. Grade: > 95%. CAS No. 36517-91-6. Molecular formula: C11H10O4. Mole weight: 206.19. | |
| Donepezil Impurity 22 | Donepezil Impurity 22 is one of Donepezil impurities. Donepezil, a highly specific reversible acetylcholinesterase (AChE) inhibitor, is used to treat moderate to severe Alzheimer's disease. Molecular formula: C24H31NO4. Mole weight: 397.51. | |
| Donepezil Impurity 3 | Donepezil impurity. Synonyms: 3-Keto Donepezil; 2-((1-Benzylpiperidin-4-yl)methyl)-5,6-dimethoxy-1H-indene-1,3(2H)-dione; 5,6-Dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-1H-indene-1,3(2H)-dione. Grade: > 95%. CAS No. 1023500-88-0. Molecular formula: C24H27NO4. Mole weight: 393.48. | |
| Donepezil Impurity 4 | Donepezil Impurity 4 is one of Donepezil impurities. Donepezil, a highly specific reversible acetylcholinesterase (AChE) inhibitor, is used to treat moderate to severe Alzheimer's disease. Molecular formula: C24H29NO3. Mole weight: 379.49. | |
| Donepezil Impurity 6 | Donepezil Impurity 6 is one of Donepezil impurities. Donepezil, a highly specific reversible acetylcholinesterase (AChE) inhibitor, is used to treat moderate to severe Alzheimer's disease. Molecular formula: C31H35NO3. Mole weight: 469.61. | |
| Donepezil Impurity 7 | Donepezil impurity. Synonyms: 2,3-Dihydro-2-[[4-hydroxy-1-(phenylmethyl)-4-piperidinyl]methyl]-5,6-dimethoxy-1H-inden-1-one; 2-((1-Benzyl-4-hydroxypiperidin-4-yl)methyl)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one. Grade: > 95%. CAS No. 197010-22-3. Molecular formula: C24H29NO4. Mole weight: 395.49. | |
| Donepezil Impurity 7 HCl | Donepezil Impurity 7 HCl is one of Donepezil impurities. Donepezil, a highly specific reversible acetylcholinesterase (AChE) inhibitor, is used to treat moderate to severe Alzheimer's disease. Molecular formula: C24H29NO4.HCl. Mole weight: 431.95. | |
| Donepezil Impurity 8 | Donepezil Impurity 8 is one of Donepezil impurities. Donepezil, a highly specific reversible acetylcholinesterase (AChE) inhibitor, is used to treat moderate to severe Alzheimer's disease. Grade: ≥ 95%. CAS No. 1808997-65-0. Molecular formula: C18H23NO4. Mole weight: 317.38. | |
| Donepezil Impurity 9 | Donepezil Impurity 9 is one of Donepezil impurities. Donepezil, a highly specific reversible acetylcholinesterase (AChE) inhibitor, is used to treat moderate to severe Alzheimer's disease. Molecular formula: C26H33NO4. Mole weight: 423.54. | |
| Donepezil N-Oxide | A metabolite of Donepezil, which is a medication for the treatment of Alzheimer's disease. Synonyms: rac (cis/trans) Donepezil N-Oxide; 2,3-Dihydro-5,6-dimethoxy-2-[[1-oxido-1-(phenylmethyl)-4-piperidinyl]methyl]-1H-inden-1-one. Grade: 95%. CAS No. 120013-84-5. Molecular formula: C24H29NO4. Mole weight: 395.49. | |
| Donepezil O-Benzyl Enol Ether | Donepezil O-Benzyl Enol Ether is one of Donepezil derivatives. Donepezil, a highly specific reversible acetylcholinesterase (AChE) inhibitor, is used to treat moderate to severe Alzheimer's disease. Synonyms: Donepezil Impurity C. Molecular formula: C31H35NO3. Mole weight: 469.61. | |
| Donepezil Open-Ring Keto Acid | Donepezil Open-Ring Keto Acid is an impurity of Donepezil, a medication for the treatment of Alzheimer's disease. Synonyms: 2-[3-(1-Benzylpiperidin-4-yl)-2-oxopropyl]-4,5-dimethoxybenzoic acid. CAS No. 197010-25-6. Molecular formula: C24H29NO5. Mole weight: 411.498. | |
| Donepezil related compound A | (2E)-Dehydrodonepezil is a derivative of Donepezil. Synonyms: (E)-2,3-Dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methylene]-1H-Inden-1-one; 2-(1-Benzylpiperidin-4-ylmethylidene)-5,6-dimethoxyindan-1-one. Grade: > 95%. CAS No. 145546-80-1. Molecular formula: C24H27NO3. Mole weight: 377.49. | |
| Donepezil related compound (E/Z mixture) | Donepezil related compound (E/Z mixture) is one of Donepezil impurities. Donepezil, a highly specific reversible acetylcholinesterase (AChE) inhibitor, is used to treat moderate to severe Alzheimer's disease. Molecular formula: C24H27NO3. Mole weight: 377.48. | |
| Donidalorsen sodium | Donidalorsen sodium, an innovative antisense oligonucleotide, selectively targets apolipoprotein C-III mRNA, effectively ameliorating dyslipidemia. Its mechanism of action involves lowering triglyceride levels, thus showing promise in the treatment of cardiovascular ailments. Ongoing research aims to further elucidate its therapeutic potential and safety profile. CAS No. 2304701-45-7. Molecular formula: C296H435N83Na20O151P20S15. Mole weight: 9112.16. | |
| Donitriptan | Donitriptan is a novel 5-hydroxytryptamine (5-HT) derivative with potent, selective, and unique high intrinsic activity at 5-HT1B/1D receptors in models relevant to migraine. Synonyms: 1-[[[3-(2-Aminoethyl)-1H-indol-5-yl]oxy]acetyl]-4-(4-cyanophenyl)-piperazinehydrochloride. Grade: >98 %. CAS No. 170912-52-4. Molecular formula: C23H25N5O2. Mole weight: 403.48. | |
| Donitriptan hydrochloride | The hydrochloride salt form of Donitriptan, which is a novel 5-HT derivative with potent, selective, and unique high intrinsic activity at 5-HT1B/1D receptors and could be probably used as an antimigraine agent. Synonyms: 1-[[[3-(2-Aminoethyl)-1H-indol-5-yl]oxy]acetyl]-4-(4-cyanophenyl)-piperazine hydrochloride; 4-[4-[2-[[3-(2-Aminoethyl)-1H-indol-5-yl]oxy]acetyl]-1-piperazinyl]benzonitrile Hydrochloride. Grade: ≥98% by HPLC. CAS No. 170911-68-9. Molecular formula: C23H25N5O2.HCl. Mole weight: 439.94. | |
| Dooku1 | Dooku1 is an analog of Yoda1 and an antagonist of the endogenous Piezo1 channel. Dooku1 inhibited 2 μM Yoda1-induced Ca2+-entry with IC50s of 1.3 μM (HEK 293 cells) and 1.5 μM (HUVECs). Synonyms: Dooku 1. CAS No. 2253744-54-4. Molecular formula: C13H9Cl2N3OS. Mole weight: 326.20. | |
| Dooku 1 | Dooku 1 reversibly blocks Yoda1 activity (IC50 = ~1.5 μM) and has no effect on constitutive Piezo1 channel activity, but it can antagonize Yoda1-induced Piezo1 activation in endothelial cells, and inhibits Yoda1-induced Ca2+-entry in vitro. Synonyms: 2-[(2,6-Dichlorobenzyl)thio)-5-(1H-pyrrol-2-yl)-1,3,4-oxadiazole. Grade: ≥98% by HPLC. Molecular formula: C13H9Cl2N3OS. Mole weight: 326.2. | |
| Dopamine D2 receptor antagonist-1 | Dopamine D2 receptor antagonist-1 is a negative allosteric modulator (NAM) of the dopamine D2 receptor (D2R) with sub-mM affinity. Synonyms: N-Cyclobutyl-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4-amine. Grade: ≥95%. CAS No. 1055411-77-2. Molecular formula: C14H17N3S. Mole weight: 259.37. | |
| Dopamine D3 receptor antagonist-1 | Dopamine D3 receptor antagonist-1, a dopamine D3 receptor-selective or multitarget bitopic ligand (Ki = 1.58 nM), is potentially useful for central nervous system disorders. Synonyms: Dopamine D3 receptor antagonist-1; CS-0227287. Molecular formula: C31H35Cl2N3O3. Mole weight: 568.53. | |
| Dopamine D3 receptor antagonist-2 | Dopamine D3 receptor antagonist-2, a dopamine D3 receptor-selective (Ki = 2.16 nM) or multitarget bitopic ligand, is potentially useful for central nervous system disorders. Synonyms: Dopamine D3 receptor antagonist-2; CS-0227288. Molecular formula: C23H27Cl2N3O3. Mole weight: 464.38. | |
| Dopamine HCl | Dopamine HCl is a catecholamine neurotransmitter present in a wide variety of animals, and a dopamine D1-5 receptors agonist. Synonyms: 4-(2-Aminoethyl)-1,2-benzenediol Hydrochloride; 4-(2-Aminoethyl)pyrocatechol Hydrochloride; 2-(3,4-Dihydroxyphenyl)ethyl-1,1,2,2-amine Hydrochloride. Grade: >98%. CAS No. 62-31-7. Molecular formula: C8H12ClNO2. Mole weight: 189.64. | |
| Dopamine Impurity C (3,4-Dimethoxyphenethylamine) | A methylated metabolite of Dopamine. Synonyms: 2-(3,4-Dimethoxyphenyl)-1-aminoethane; 2-(3,4-Dimethoxyphenyl)ethanamine; 2-(3,4-Dimethoxyphenyl)ethylamine; 3,4-Di-O-methyldopamine; 3,4-Dimethoxy-β-phenylethylamine. Grade: > 95%. CAS No. 120-20-7. Molecular formula: C10H15NO2. Mole weight: 181.24. | |
| Dopexamine | Dopexamine is a synthetic dopamine analog and acts as a β2-adrenergic receptor agonist as well as an agonist at peripheral dopamine receptors. It has been used to improve myocardial and renal performance in patients suffering from low cardiac output states. Uses: Adrenergic beta-agonists. Synonyms: 1,2-Benzenediol, 4-[2-[[6-[(2-phenylethyl)amino]hexyl]amino]ethyl]-; 4-[2-[[6-[(2-Phenylethyl)amino]hexyl]amino]ethyl]-1,2-benzenediol; FPL 60278; 4-(2-((6-(Phenethylamino)hexyl)amino)ethyl)pyrocatechol. Grade: 95%. CAS No. 86197-47-9. Molecular formula: C22H32N2O2. Mole weight: 356.50. | |
| Dopexamine hydrochloride | Dopexamine is a synthetic dopamine analog and acts as a β2-adrenergic receptor agonist as well as an agonist at peripheral dopamine receptors. It has been used to improve myocardial and renal performance in patients suffering from low cardiac output states. Synonyms: 4-[2-[[6-[(2-Phenylethyl)amino]hexyl]amino]ethyl]-1,2-benzenediol Dihydrochloride; Dopacard; Dopexamine Dihydrochloride; FPL 60278AR. Grade: 95%. CAS No. 86484-91-5. Molecular formula: C22H34Cl2N2O2. Mole weight: 429.43. | |
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