BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| D-Ribose-5-phosphate disodium salt dihydrate | D-Ribose-5-phosphate disodium salt dihydrate, a metabolic intermediate and biochemical precursor of nucleotides and nucleic acids, also participates in ATP biosynthesis through the oxidative phase of the pentose phosphate pathway. Based on its molecular properties, this compound shows immense potential for medicinal utility and clinical intervention in various genetic disorders and malignancies. Synonyms: D-Ribose, 5-(dihydrogen phosphate), sodium salt, hydrate (1:2:2); D-Ribose, 5-(dihydrogen phosphate), disodium salt, dihydrate. CAS No. 207671-46-3. Molecular formula: C5H9Na2O8P.2H2O. Mole weight: 310.10. |  |
| D-Ribose-5-phosphate disodium salt hydrate | D-Ribose-5-phosphate disodium salt hydrate is a pivotal biomolecule extensively utilized in the biomedical sector, showcasing remarkable enzymatic attributes while serving as a pivotal participant in nucleotide and nucleic acid biosynthesis. It finds extensive application as a precursor in DNA and RNA synthesis. Synonyms: D-Ribofuranose 5-phosphate disodium salt. CAS No. 18265-46-8. Molecular formula: C5H9Na2O8P H2O. Mole weight: 274.07. | |
| D-Ribulose 5-phosphate sodium salt | D-Ribulose 5-phosphate sodium salt is a pivotal intermediate in the intricate pentose phosphate pathway, playing a paramount role in research of metabolic intricacies. As an inherent substrate, this compound fearlessly partakes in diverse enzymatic reactions, steering the synthesis of vital biomolecules. Synonyms: Ru-5-P; erythro-Pentulose 5-phosphate. CAS No. 352525-12-3. Molecular formula: C5H11O8P.xNa. Mole weight: 230.11 (free acid basis). | |
| D-Ribulose - Aqueous solution | D-Ribulose - Aqueous solution is a vital component used in the biomedical industry. It serves as a key ingredient for medicines targeting respiratory diseases and also aids in drug development related to cardiovascular disorders like hypertension and atherosclerosis. Synonyms: D-Adonose; D-erythro-2-Ketopentose; D-erythro-2-Pentulose; D-Arabinulose; D-Araboketose. CAS No. 488-84-6. Molecular formula: C5H10O5. Mole weight: 150.13. | |
| DRI-C21045 | DRI-C21045 is an inhibitor of the CD40-CD40L costimulatory protein-protein interaction with IC50 of 0.17 μM. DRI-C21045 shows concentration-dependent inhibition of the activation of NF-κB in CD40 sensor cells. DRI-C21045 also concentration-dependently inhibits CD40L-induced B cell proliferation in a statistically significant manner at concentrations higher than 10 μM. Synonyms: 8-(4'-(4-(Methoxycarbonyl)benzamido)biphenyl-4-ylcarboxamido)naphthalene-1-sulfonic acid. Grade: 98%. CAS No. 2101765-81-3. Molecular formula: C32H24N2O7S. Mole weight: 580.61. | |
| Drinabant | Drinabant is a highly potent, selective antagonist for the CB1 receptor with Ki values of 0.16-0.44 nM. Uses: Cannabinoid receptor cb1 antagonists. Synonyms: AVE1625; AVE 1625; AVE-1625; Drinabant.N-[1-[bis(4-chlorophenyl)methyl]azetidin-3-yl]-N-(3,5-difluorophenyl)methanesulfonamide. Grade: ≥98%. CAS No. 358970-97-5. Molecular formula: C23H20Cl2F2N2O2S. Mole weight: 497.38. | |
| Drinidene | Drinidene is a bio-active chemical compound. Synonyms: 2-(Aminomethylene)-1-indanone; NSC-299237; CP-24877; CP24877; CP 24877; 1H-Inden-1-one, 2-(aminomethylene)-2,3-dihydro-. Grade: 98%. CAS No. 53394-92-6. Molecular formula: C10H9NO. Mole weight: 159.18. | |
| Drofenine hydrochloride | Drofenine hydrochloride is a widely used anticholinergic acts on smooth muscle to stop muscle spasms. Uses: A potent competitive inhibitor of bche. Synonyms: 2-(diethylamino)ethyl 2-cyclohexyl-2-phenylacetate; hydrochloride; α-Cyclohexyl-benzeneacetic Acid 2-(Diethylamino)ethyl Ester Hydrochloride. Grade: ≥98%. CAS No. 548-66-3. Molecular formula: C20H32ClNO2. Mole weight: 353.93. | |
| Droloxifene | Droloxifene is a third-generation selective estrogen receptor modulator (SERM) with structural similarity to tamoxifen but designed for improved efficacy and reduced side effects. It exhibits stronger anti-estrogenic activity in breast tissue while minimizing uterine stimulation, making it a candidate for breast cancer therapy. Synonyms: (E)-3-(1-(4-(2-(Dimethylamino)ethoxy)phenyl)-2-phenylbut-1-en-1-yl)phenol; 3-[(1E)-1-[4-[2-(Dimethylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]phenol; 3-[(1E)-1-[4-[2-(Dimethylamino)ethoxy]phenyl]-2-phenyl-1-butenyl]phenol; (E)-3-[1-[4-[2-(Dimethylamino)ethoxy]phenyl]-2-phenyl-1-butenyl]phenol; 3-Hydroxytamoxifen; E-Droloxifene. Grade: 98%. CAS No. 82413-20-5. Molecular formula: C26H29NO2. Mole weight: 387.52. | |
| Dronedarone | Dronedarone is a Class III antiarrhythmic and a multi-channel blocker for atrial fibrillation. It blocks potassium, sodium, and calcium channels and also exhibits antiadrenergic properties. Uses: Antiarrhythmic. Synonyms: Multaq; SR-33589; SR33589; SR 33589; SR-33589B. Grade: >98%. CAS No. 141626-36-0. Molecular formula: C31H44N2O5S. Mole weight: 556.76. | |
| Dronedarone Hydrochloride Impurity B | N-Mesyldronedarone is an impurity of Dronedarone. Synonyms: N-[2-Butyl-3-[4-[3-(dibutylamino)propoxy]benzoyl]-5-benzofuranyl]-N-(methylsulfonyl)-methanesulfonamide. Grade: > 95%. CAS No. 141626-57-5. Molecular formula: C32H46N2O7S2. Mole weight: 634.85. | |
| Dronedarone Impurity 1 | Dronedarone Impurity. Synonyms: SCHEMBL9485915; (5-?Amino-?2-?butyl-?3-?benzofuranyl)?[4-?[3-?(butylamino)?propoxy]?phenyl]?methanone; 141626-26-8. Grade: > 95%. CAS No. 141626-26-8. Molecular formula: C26H34N2O3. Mole weight: 422.57. | |
| Droperidol | Droperidol is a potent antagonist of dopamine subtype 2 receptors in the limbic system. Uses: Adjuvants, anesthesia; antiemetics; antipsychotic agents; dopamine antagonists. Synonyms: NSC 169874; NSC-169874; NSC-169874. Grade: >98%. CAS No. 548-73-2. Molecular formula: C22H22FN3O2. Mole weight: 379.43. | |
| Droperidol Impurity D | An impurity of Droperidol. Synonyms: Droperidol N-Oxide; 466118-75-2. Grade: > 95%. CAS No. 466118-75-2. Molecular formula: C22H22FN3O3. Mole weight: 395.44. | |
| Droperidol Impurity E | An impurity of Droperidol. Synonyms: 1-[1-[4-[4-[4-(2-Oxo-2,3-dihydro-1H-benzimidazol-1-yl)-3,6-dihydropyridin-1(2H)-yl]-1-oxobutyl]phenyl]-1,2,3,6-tetrahydro-4-pyridinyl]-1,3-dihydro-2H-benzimidazol-2-one. Grade: > 95%. CAS No. 1346604-17-8. Molecular formula: C34H34N6O3. Mole weight: 574.67. | |
| Dropropizine | Dropropizine is a racemic non-opiate antitussive agent, it is used as a cough suppressant.Dropropizine exhibits antitussive activity in cats noticeably lower than Pinacidil and Codeine. Synonyms: UCB-1967; UCB 1967; UCB1967. Grade: >98%. CAS No. 17692-31-8. Molecular formula: C13H20N2O2. Mole weight: 236.31. | |
| Drospirenone Acid Sodium Salt | Drospirenone Acid Sodium Salt is a derivative of Drospirenone. Synonyms: [6R-(6α,7α,8β,9α,10β,13β,14α,15β,16β,17β)]-2,3,6,7,8,9,10,11,12,13,14,15,16,17,20,21-Hexadecahydro-17-hydroxy-10,13-dimethyl-3-oxo-1H-dicyclopropa[6,7:15,16]cyclopenta[a]phenanthrene-17-propanoic Acid Sodium Salt. Grade: > 95%. CAS No. 1393356-37-0. Molecular formula: C24H31NaO4. Mole weight: 407.5. | |
| Drospirenone Impurity D | An intermediate in the synthesis of Drospirenone. Synonyms: (15α,16α,17α)-15,16-Dihydro-17-hydroxy-3-oxo-3'H-cyclopropa[15,16]pregna-4,6,15-triene-21-carboxylic Acid γ-Lactone; 17β-Hydroxy-15β,16β-methylene-3-oxo-17α-pregna-4,6-diene-21-carboxylic Acid γ-Lactone. Grade: > 95%. CAS No. 67372-69-4. Molecular formula: C23H28O3. Mole weight: 352.48. | |
| Drospirenone Impurity (Drospirenone Lactol) | 5'-Hydroxy Drospirenone is an impurity of Drospirenone. Synonyms: (2'S,6R,7R,8R,9S,10R,13S,14S,15S,16S)-1,4',5',6,7,8,9,10,11,12,13,14,15,16,20,21-Hexadecahydro-5'-hydroxy-10,13-dimethyl-spiro[17H-dicyclopropa[6,7:15,16]cyclopenta[a]phenanthrene-17,2'(3'H)-furan]-3(2H)-one. Grade: > 95%. CAS No. 863329-71-9. Molecular formula: C24H32O3. Mole weight: 368.52. | |
| Drospirenone Related Impurity 1 | An intermediate in the synthesis of Drospirenone. Drospirenone impurity. Synonyms: (15α,16α,17α)-15,16-Dihydro-17-hydroxy-3-oxo-3'H-cyclopropa[15,16]pregna-4,15-diene-21-carboxylic Acid γ-Lactone; 15β,16β-Methylene-3-oxo-17α-pregn-4-ene-21,17-carbolactone; 17β-Hydroxy-15β,16β-methylene-3-oxo-17α-pregn-4-ene-21-carboxylic Acid γ-Lactone. Grade: > 95%. CAS No. 67372-68-3. Molecular formula: C23H30O3. Mole weight: 354.49. | |
| Drotaveraldine | Drotaveraldine is a metabolite of Drotaverine, a phosphodiesterase 4 inhibitor. Synonyms: (6,7-Diethoxy-3,4-dihydro-1-isoquinolinyl)(3,4-diethoxyphenyl)methanone. CAS No. 54088-62-9. Molecular formula: C24H29NO5. Mole weight: 411.49. | |
| Droxicainide hydrochloride | The hydrochloride salt form of Droxicainide, a piperidine derivative, has been found to be an potential antiarrhythmic agent. Synonyms: Droxicainide hydrochloride; AL-S 1249; Droxicainide HCl; S 1249; S-1249; UNII-91801A0812. (+-)-N-(2-Hydroxyethyl)pipecolinyl-2,6-dimethylanilide hydrochloride; S-1249; (+-)-N-(2,6-Dimethylphenyl)-1-(2-hydroxyethyl)-2-piperidinecarboxamide monohydrochloride; 2-Piperidinecarboxamide, N-(2,6-dimethylphenyl)-1-(2-hydroxyethyl)-, monohydrochloride. Grade: 98%. CAS No. 149572-05-4. Molecular formula: C16H25ClN2O2. Mole weight: 312.84. | |
| Droxidopa | Droxidopa is a synthetic amino acid precursor which acts as a prodrug to the neurotransmitters norepinephrine (noradrenaline) and epinephrine (adrenaline). It is capable of crossing the protective blood-brain barrier. Synonyms: (βR)-β,3-Dihydroxy-L-tyrosine; threo-β,3-Dihydroxy-L-tyrosine; L-threo-3-(3,4-Dihydroxyphenyl)serine; (-)-threo-3,4-Dihydroxyphenylserine; (2S,3R)-3-(3,4-Dihydroxyphenyl)-2-amino-3-hydroxypropanoic Acid; DOPS; L-DOPS; L-Threodops; L-threo-3,4-Dihydroxyphenylserine; L-threo-DOPS; L-threo-β-(3,4-Dihydroxyphenyl)serine; SM 5688; threo-Dopaserine. Grade: >98%. CAS No. 23651-95-8. Molecular formula: C9H11NO5. Mole weight: 213.19. | |
| Droxinostat | Droxinostat is a selective inhibitor of HDAC3, HDAC6, and HDAC8. Droxinostat shows comparable inhibition of HDAC6 and HDAC8 (IC50 = 2.47 and 1.46 μmol/L, respectively). Synonyms: NS 41080; NS-41080; NS41080; 4-(4-Chloro-2-methylphenoxy)-N-hydroxybutanamide. CAS No. 99873-43-5. Molecular formula: C11H14ClNO3. Mole weight: 243.687. | |
| Drozitumab | Drozitumab is a human monoclonal antibody directed against DR5. DR5 is a ell surface receptor of the TNF-receptor superfamily that binds TRAIL and mediates apoptosis. Study showed that Drozitumab was effective against Rhabdomyosarcoma cell lines. Synonyms: PRO-95780; PRO 95780; PRO95780; rhuMAb-DR 5. Grade: 95%. CAS No. 912628-39-8. Molecular formula: C6334H9792N1700O2000S42. Mole weight: 143.1 kDa. | |
| DRX-065 | DRX-065 is a deuterated R enantiomer of pioglitazone, an antidiabetic drug. DRX-065 exhibits anti-inflammatory property without weight-gain side effect of S enatiomer. Synonyms: deuterated R-enantiomer of pioglitazone; (R)-5-(4-(2-(5-ethylpyridin-2-yl)ethoxy)benzyl)thiazolidine-2,4-dione-5-d. CAS No. 1259828-75-5. Molecular formula: C19H19DN2O3S. Mole weight: 357.126. | |
| DS-1001b | DS-1001b is an oral selective inhibitor of mutant IDH1 R132X. DS-1001b impaired the proliferation of chondrosarcoma cells with IDH1 mutations in vitro and in vivo, and decreased 2-HG levels. Synonyms: DS-1001; DS 1001; DS1001. CAS No. 1898207-64-1. Molecular formula: C29H29Cl3FN3O4. Mole weight: 608.92. | |
| DS-1040 Tosylate | DS-1040 inhibits the activated form of thrombin-activatable fibrinolysis inhibitor (TAFIa), used for the treatment of acute ischemic stroke (AIS). DS-1040 substantially decreased TAFIa activity but had no impact on bleeding time. DS-1040 may provide an option of safer thrombolytic therapy. Synonyms: DS-1040 Tosylate; DS 1040 Tosylate; DS1040 Tosylate; (2S)-5-amino-2-[[1-(4-methylcyclohexyl)imidazol-4-yl]methyl]pentanoic acid; 4-methylbenzenesulfonic acid; DS-1040 (Tosylate). CAS No. 1335138-89-0. Molecular formula: C23H35N3O5S. Mole weight: 465.61. | |
| DS-1205b free base | DS-1205b free base, a potent and selective AXL kinase inhibitor with an IC50 of 1.3 nM, inhibits cell migration in vitro and tumor growth in vivo. It also inhibits MER, MET and TRKA with IC50s of 63, 104 and 407 nM, respectively. Synonyms: (R)-N-(4-(5-(4-((1,4-Dioxan-2-yl)methoxy)-3-methoxyphenyl)-2-aminopyridin-3-yl)-3-fluorophenyl)-5-methyl-4'-oxo-1'-((tetrahydro-2H-pyran-4-yl)methyl)-1',4'-dihydro-[2,3'-bipyridine]-5'-carboxamide; N-[4-(2-Amino-5-{4-[(2R)-1,4-dioxan-2-ylmethoxy]-3-methoxyphenyl}-3-pyridinyl)-3-fluorophenyl]-5-methyl-4'-oxo-1'-(tetrahydro-2H-pyran-4-ylmethyl)-1',4'-dihydro-2,3'-bipyridine-5'-carboxamide; DS-1205b; DS-1205. Grade: ≥95%. CAS No. 1855860-24-0. Molecular formula: C41H42FN5O7. Mole weight: 735.80. | |
| DS-1558 | This active molecular is a potent GPR40 agonist and it was found to have potent glucose lowering effects during an oral glucose tolerance test in animal models. DS-1558 improved hyperglycemia and increased insulin secretion dose-dependently during the oral glucose tolerance test in Zucker fatty rats. Uses: Improve hyperglycemia and increase insulin secretion. Synonyms: DS-1558; DS 1558; DS1558; (S)-3-ethoxy-3-(4-(((R)-4-(trifluoromethyl)-2,3-dihydro-1H-inden-1-yl)oxy)phenyl)propanoic acid. Grade: 98%. CAS No. 1202575-67-4. Molecular formula: C21H21F3O4. Mole weight: 394.39. | |
| DS16570511 | DS16570511 is an inhibitor of the mitochondrial calcium uniporter, which blocks the MCU- or MICU1-dependent increase of Ca2+ influx. It inhibits calcium uptake by mitochondria isolated from HEK293A cells, rat heart, and pig heart (IC50s = 0.86, 25, and 15 μM, respectively). Synonyms: 4-(3-(3-(((3-(2,6-dichlorophenyl)-5-methylisoxazol-4-yl)methyl)amino)benzoyl)-1H-indol-1-yl)butanoic acid. Grade: ≥95%. Molecular formula: C30H25Cl2N3O4. Mole weight: 562.44. | |
| DS-1971a | DS-1971a is a potent and selective NaV1.7 inhibitor. DS-1971a is expected to exert potent efficacy in patients with peripheral neuropathic pain, with a favorable safety profile. Synonyms: DS-1971. Grade: 98% by HPLC. CAS No. 1450595-86-4. Molecular formula: C20H21ClFN5O3S. Mole weight: 465.9. | |
| DS2 | DS2 has been found to be a positive allosteric modulator of δ-GABAA receptors and could probably be useful against analgesics as well as sleep disorders. Synonyms: DS2; DS-2; DS 2; 4-Chloro-N-[2-(2-thienyl)imidazo[1,2-a]pyridin-3-yl]benzamide. Grade: ≥97% by HPLC. CAS No. 374084-31-8. Molecular formula: C18H12ClN3OS. Mole weight: 353.83. | |
| DS20362725 | DS20362725, an agonist of estrogen-related receptor α (ERRα), inhibits the binding between receptor-interacting protein 140 (RIP140) corepressor peptide and GST-ERRα ligand-binding domain (LBD) with an IC50 of 0.6 μM. It can be used to study metabolic disorders, including type 2 diabetes mellitus (T2DM). Synonyms: Phenol, 4-[(1,2-dimethyl-1H-benzimidazol-6-yl)oxy]-2-(1,1-dimethylethyl)-; 2-(tert-butyl)-4-((1,2-dimethyl-1H-benzo[d]imidazol-6-yl)oxy)phenol. CAS No. 2735803-20-8. Molecular formula: C19H22N2O2. Mole weight: 310.39. | |
| DS-2248 | DS-2248 is an orally active and small molecule inhibitor of Hsp90, with potential antineoplastic activity. Upon oral administration, Hsp90 inhibitor DS-2248 specifically blocks Hsp90, which inhibits its chaperone function and promotes the proteasomal degradation of oncogenic signaling proteins involved in tumor cell proliferation and survival. This may result in an inhibition of tumor cell proliferation. Synonyms: DS2248; DS-2248; DS 2248. Grade: >98%. CAS No. 1696408-04-4. | |
| DS-437 | DS-437 is a dual inhibitor of protein arginine methyltransferase 5/7 (PRMT5/7) with IC50s of 5.9 and 6 μM, respectively. It is selective for PRMT5 and PRMT7 over 29 other human protein-, DNA-, and RNA-methyltransferases. It is a S-adenosylmethionine (SAM)-competitive inhibitor of PRMT5, and inhibits the methylation of FOXP3, and inhibits DNMT3A and DNMT3B with IC50s of 52 and 62 μM, respectively. Synonyms: 5'-S-[2-[[(ethylamino)carbonyl]amino]ethyl]-5'-thio-adenosine; 5'-S-{2-[(Ethylcarbamoyl)amino]ethyl}-5'-thioadenosine. Grade: ≥95%. CAS No. 1674364-87-4. Molecular formula: C15H23N7O4S. Mole weight: 397.45. | |
| DS44960156 | DS44960156 is a potent and selective MTHFD2 inhibitor with IC50 of 1.6 μM. Synonyms: 4-(5-Oxo-2,3,4,5-tetrahydro-1H-chromeno[3,4-c]pyridine-3-carbonyl)benzoic acid. Grade: 99%. CAS No. 2361327-08-2. Molecular formula: C20H15NO5. Mole weight: 349.34. | |
| DS45500853 | DS45500853, an agonist of estrogen-related receptor α (ERRα), inhibits the binding between receptor-interacting protein 140 (RIP140) corepressor peptide and GST-ERRα ligand-binding domain (LBD) with an IC50 of 0.80 μM. It can be used to study metabolic disorders, including type 2 diabetes mellitus (T2DM). Synonyms: 1-[4-(3-tert-Butyl-4-hydroxyphenoxy)phenyl]ethan-1-one; Ethanone, 1-[4-[3-(1,1-dimethylethyl)-4-hydroxyphenoxy]phenyl]-. CAS No. 2735803-28-6. Molecular formula: C18H20O3. Mole weight: 284.35. | |
| DS86760016 | DS86760016 is a potent leucyl-tRNA synthetase (LeuRS) inhibitor with activity against multidrug-resistant (MDR) Gram-negative bacteria. DS86760016 inhibits LeuRS enzymes from Escherichia coli, Pseudomonas aeruginosa, and Acinetobacter baumannii, with IC50s of 0.38, 0.62, and 0.16 μM, respectively. Synonyms: (S)-3-(Aminomethyl)-[1,3]dioxolo[4',5':5,6]benzo[1,2-c][1,2]oxaborol-1(3H)-ol hydrochloride. CAS No. 1853176-89-2. Molecular formula: C9H11BClNO4. Mole weight: 243.45. | |
| DS88790512 | DS88790512 is a potent, selective and orally bioavailable inhibitor of TRPC6 (IC50 = 11 nM). Synonyms: 4-({(1R,2R,3aR,7aS)-2-[(3R)-3-Amino-1-piperidinyl]-7a-methyl-5-oxooctahydro-1H-inden-1-yl}oxy)benzonitrile; Benzonitrile, 4-[[(1R,2R,3aR,7aS)-2-[(3R)-3-amino-1-piperidinyl]octahydro-7a-methyl-5-oxo-1H-inden-1-yl]oxy]-. Grade: ≥90%. CAS No. 2231089-95-3. Molecular formula: C22H29N3O2. Mole weight: 367.48. | |
| D-Saccharic acid 1,4-lactone | D-Saccharic acid 1,4-lactone, a versatile compound extensively investigated in the field of biomedicine, holds significant therapeutic potential against various ailments like cardiovascular diseases, diabetes, and cancer. Its remarkable attributes as an antioxidant, anti-inflammatory, and anticancer agent make it an invaluable asset contributing to advancements in drug exploration and progress. Synonyms: D-Glucaric acid, 1,4-lactone; Glucaric acid, 1,4-lactone, D-; D-Glucaric-1,4-lactone; D-Glucaro-1,4-lactone; Saccharic acid 1,4-lactone; Glucaro-1,4-lactone; Saccharo-1,4-lactone; (2S)-[(2S,3R,4R)-3,4-Dihydroxy-5-oxotetrahydro-2-furanyl](hydroxy)acetic acid. Grade: ≥95%. CAS No. 389-36-6. Molecular formula: C6H8O7. Mole weight: 192.12. | |
| D-Sedoheptulose | D-Sedoheptulose, renowned for its potential in treating an array of maladies such as cancer, diabetes, and inflammation, yields a panoply of benefits. First and foremost, this rare sugar has the capacity to thwart tumor proliferation and curtail glucose regulation. Excitingly, D-Sedoheptulose impressively re-calibrates the immune system and imbues anti-inflammatory effects. With such standout characteristics, the future may bode well for D-Sedoheptulose's prospects as a sought-after future drug. Synonyms: D-altro-2-Heptulose; Sedoheptulose; D-altro-Heptulose; D-Altroheptulose. CAS No. 3019-74-7. Molecular formula: C7H14O7. Mole weight: 210.18. | |
| D-Sedoheptulose-[2,3,4,5,6,7-13C6] | D-Sedoheptulose-[2,3,4,5,6,7-13C6]. Synonyms: D-Sedoheptulose-2,3,4,5,6,7-13C6. | |
| D-Sedoheptulose-7-phosphate-[2,3,4,5,6,7-13C6] barium salt | D-Sedoheptulose-7-phosphate-[2,3,4,5,6,7-13C6] barium salt. Synonyms: D-Sedoheptulose-7-phosphate-2,3,4,5,6,7-13C6 barium salt. | |
| D-Sedoheptulose-7-phosphate barium salt | D-Sedoheptulose-7-phosphate barium salt is an essential biomedical agent, emerging as a pivotal catalyst across multifarious ailments. Embracing an indispensible role in the intricate orchestration of metabolic pathways and carbohydrate metabolism, its application extends to the research of enigmatic conditions like diabetes, metabolic syndrome, and glycolysis-related afflictions. Synonyms: D-SEDOHEPTULOSE-7-PHOSPHATE BARIUM SALT; J-016442. CAS No. 17187-72-3. Molecular formula: C7H13O10PBa. Mole weight: 425.47. | |
| D-Sedoheptulose 7-phosphate lithium salt | D-Sedoheptulose 7-phosphate lithium salt is a pivotal compound assuming a paramount role in studying intricate metabolic pathways linked to malignant neoplasms and glucose mishandling disorders. Synonyms: D-altro-Heptulose 7-phosphate lithium salt. Molecular formula: C7H15O10P.xLi. Mole weight: 290.16 (free acid basis). | |
| D-Ser(11)-Semaglutide | D-Ser(11)-Semaglutide is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: D-[Ser]-11-Semaglutide; (3S,9S,12S,15S,18S,21S,24S,27R,30S,33S,36S,39S,45S,48S,51S,54S,81R)-54-(((6S,12S,15S,18S,21S,24S,27S,30S,33S)-21-((1H-indol-3-yl)methyl)-1-amino-30-benzyl-27-((S)-sec-butyl)-35-carboxy-6-((carboxymethyl)carbamoyl)-12-(3-guanidinopropyl)-1-imino-18-isobutyl-15-isopropyl-24-methyl-8,11,14,17,20,23,26,29,32-nonaoxo-2,7,10,13,16,19,22,25,28,31-decaazapentatriacontan-33-yl)carbamoyl)-3-(2-((S)-2-amino-3-(1H-imidazol-4-yl)propanamido)-2-methylpropanamido)-45-(3-amino-3-oxopropyl)-12-benzyl-39-(2-carboxyethyl)-21-(carboxymethyl)-33-(4-hydroxybenzyl)-9,15-bis((R)-1-hydroxyethyl)-18,27,30-tris(hydroxymethyl)-36-isobutyl-24-isopropyl-48,51-dimethyl-4,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,52,60,69,78,83-henicosaoxo-62,65,71,74-tetraoxa-5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,59,68,77,82-henicosaazanonanonacontane-1,81,99-tricarboxylic acid. Grade: 95%. Molecular formula: C187H291N45O59. Mole weight: 4113.64. | |
| D-Ser(12)-Semaglutide | D-Ser(12)-Semaglutide is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: D-Ser-12-Semaglutide; (3S,9S,12S,15S,18S,21S,24S,27S,30R,33S,36S,39S,45S,48S,51S,54S,81R)-54-(((6S,12S,15S,18S,21S,24S,27S,30S,33S)-21-((1H-indol-3-yl)methyl)-1-amino-30-benzyl-27-((S)-sec-butyl)-35-carboxy-6-((carboxymethyl)carbamoyl)-12-(3-guanidinopropyl)-1-imino-18-isobutyl-15-isopropyl-24-methyl-8,11,14,17,20,23,26,29,32-nonaoxo-2,7,10,13,16,19,22,25,28,31-decaazapentatriacontan-33-yl)carbamo. Grade: 95%. Molecular formula: C187H291N45O59. Mole weight: 4113.64. | |
| D-Ser(7)-ICA | D-Ser(7)-ICA is an impurity of Icatibant, which is a selective and specific antagonist of bradykinin B2 receptor. Synonyms: H-D-Arg-Arg-Pro-Hyp-Gly-2Thi-D-Ser-D-Tic-Oic-Arg-OH. Molecular formula: C59H89N19O13S. Mole weight: 1304.52. | |
| D-Ser(8)-Semaglutide | D-Ser(8)-Semaglutide is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: D-[Ser]-8-Semaglutide; H-His-Aib-Glu-Gly-Thr-Phe-Thr-D-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(AEEAc-AEEAc-γ-Glu-17-carboxyheptadecanoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH; L-Histidyl-2-methylalanyl-L-α-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-D-seryl-L-α-aspartyl-L-valyl-L-seryl-L-seryl-L-tyrosyl-L-leucyl-L-α-glutamylglycyl-L-glutaminyl-L-alanyl-L-alanyl-N6-[N-(17-carboxy-1-oxoheptadecyl)-L-γ-glutamyl-2-[2-(2-aminoethoxy)ethoxy]acetyl-2-[2-(2-aminoethoxy)ethoxy]acetyl]-L-lysyl-L-α-glutamyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-tryptophyl-L-leucyl-L-valyl-L-arginylglycyl-L-arginylglycine. Grade: 95%. Molecular formula: C187H291N45O59. Mole weight: 4113.64. | |
| DSM265 | DSM265 is a selective DHODH (dihydroorotate dehydrogenase) inhibitor used for prevention and treatment of malaria. DSM265 is highly selective toward DHODH of the malaria parasite Plasmodium. It is efficacious against both blood and liver stages of P. falciparum and active against drug-resistant parasite isolates. Treatment for malaria was in phase II clinical trials. Uses: Malaria. Synonyms: DSM265; DSM-265; DSM 265; UNII-0Q42P4YI6B; 0Q42P4YI6B; CHEMBL1956285; SCHEMBL14053411; 2-(1,1-difluoroethyl)-5-methyl-N-[4-(pentafluoro-$l^{6}-sulfanyl)phenyl]-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine. Grade: 98%. CAS No. 1282041-94-4. Molecular formula: C14H12F7N5S. Mole weight: 415.34. | |
| DSM705 | DSM705 is a potent antimalarial compound. DSM705 is a pyrrole-based Dihydroorotate Dehydrogenase (DHODH) inhibitor. It exhibits nanomolar potency against Plasmodium DHODH and Plasmodium parasites, with no inhibition of mammalian DHODHs. CAS No. 2653225-38-6. Molecular formula: C19H19F3N6O. Mole weight: 404.39. | |
| DSM705 hydrochloride | DSM705 hydrochloride is a potent antimalarial compound. DSM705 hydrochloride is a pyrrole-based Dihydroorotate Dehydrogenase (DHODH) inhibitor. It exhibits nanomolar potency against Plasmodium DHODH and Plasmodium parasites, with no inhibition of mammalian DHODHs. Molecular formula: C19H20ClF3N6O. Mole weight: 440.85. | |
| D-Sorbitol hexaacetate | D-Sorbitol hexaacetate, a chemical compound, functions as a pharmaceutical excipient in drug formulations, improving active pharmaceutical ingredient solubility and stability. Its potential anti-inflammatory and analgesic properties suggest efficacy in treating various inflammatory disorders. Unleashing the benefits of D-Sorbitol hexaacetate as a pharmaceutical excipient empowers medical research and drives drug development towards new heights. Synonyms: D-Glucitol, 1,2,3,4,5,6-hexaacetate; D-Glucitol, hexaacetate; Glucitol, hexaacetate, D-; Sorbitol hexaacetate; 1,2,3,4,5,6-Hexa-O-acetyl-D-glucitol; L-Gulitol hexaacetate; Hexa-O-acetylglucitol; NSC 170204; Pagosten 3; Sorbityl hexaacetate. CAS No. 7208-47-1. Molecular formula: C18H26O12. Mole weight: 434.39. | |
| D-Sorbitol hexahydrate | D-Sorbitol hexahydrate is a sugar alcohol acting as an excipient in pharmaceutical preparations, notably oral compounds and syrups. Molecular formula: C6H14O6.6H2O. Mole weight: 290.26. | |
| D-Sorbose | D-Sorbose is a carbohydrate compound with potential efficacy in studyting metabolic disorders such as diabetes and obesity. Synonyms: D-Xylo-hexulose. CAS No. 3615-56-3. Molecular formula: C6H12O6. Mole weight: 180.16. | |
| DSP-1053 | DSP-1053 is a novel serotonin reuptake inhibitor with 5-HT1A partial agonistic activity. Synonyms: 6-(2-(4-(3-(2-Methoxyethoxy)-4-bromobenzyl)piperidino)ethyl)-2H-1-benzopyran-4(3H)-one. Grade: 98%. CAS No. 1176326-76-3. Molecular formula: C26H32BrNO4. Mole weight: 502.44. | |
| DSP-4 | DSP-4 has been found to be an adrenergic neurotoxin and could exhibit neurotoxic effects on both peripheral and central noradrenergic neurons. Synonyms: DSP-4; DSP 4; DSP4; N-(2-Chloroethyl)-N-ethyl-2-bromobenzylamine hydrochloride. Grade: ≥98% by HPLC. CAS No. 40616-75-9. Molecular formula: C11H15BrClN.HCl. Mole weight: 313.06. | |
| DSP-6952 hydrobromide | DSP-6952 is a novel 5-HT4 receptor partial agonist that inhibits visceral hypersensitivity and ameliorates gastrointestinal dysfunction in experimental animals. CAS No. 1184661-33-3. Molecular formula: C21H32BrClN4O5. Mole weight: 535.86. | |
| dSpacer-CEP | dSpacer is used to introduce stable abasic sites in oligonucleotides. Synonyms: 5'-O-(4,4'-Dimethoxytrityl)-1',2'-dideoxyribose-3'-O-[(2-cyanoethyl)-(N,N-Diisopropyl)]-phosphoramidite; 1',2'-Dideoxy-5'-O-DMT-ribose 3'-CE phosphoramidite; dSpacer CE Phosphoramidite; (2R,3S)-2-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; D-erythro-Pentitol, 1,4-anhydro-5-O-[bis(4-methoxyphenyl)phenylmethyl]-2-deoxy-, 3-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]. Grade: ≥95%. CAS No. 129821-76-7. Molecular formula: C35H45N2O6P. Mole weight: 620.71. | |
| DSPE-PEG2000-Tri-b-GalNAc | DSPE-PEG2000-Tri-b-GalNAc is a multifunctional lipid material designed for targeted drug delivery. It combines DSPE (1,2-distearoyl-sn-glycero-3-phosphoethanolamine) with a PEG2000 spacer and three N-acetylgalactosamine (GalNAc) moieties. This structure allows it to selectively bind to the asialoglycoprotein receptor (ASGPR) on hepatocytes, enabling efficient delivery of therapeutic agents to the liver. It is commonly used to construct liposomes or lipid nanoparticles for applications in RNA-based therapies, small molecule drug delivery, and gene delivery, enhancing the therapeutic efficacy while minimizing off-target effects. Synonyms: Tris-β-GalNAc-GABA-PEG-Phospholipid; Triantennary β-D-GalNAc-GABA-PEG-phospholipid; Tri-GalNAc-PEG2000-DSPE; (β-D-GalNAc-sp)3-NHC(O)-GABA-PEG2k-phospholipid; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[tris-GalNAc-GABA-(polyethylene glycol)-2000. Molecular formula: (C2H4O)nC115H210N13O40P. | |
| DSPE-PEG2000-triGalNAc ammonium salt | DSPE-PEG2000-triGalNAc ammonium salt is a polar lipid designed for targeted drug delivery to hepatocytes. It combines DSPE (1,2-distearoyl-sn-glycero-3-phosphoethanolamine) with a PEG2000 spacer and three N-acetylgalactosamine (triGalNAc) moieties, which enable specific binding to the asialoglycoprotein receptor (ASGPR) on liver cells. This material is widely used in the construction of liposomes or lipid nanoparticles for applications in RNA interference, gene therapy, and small molecule drug delivery. Synonyms: DSPE-PEG2000-triGalNAc ammonium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[carboxy(polyethylene glycol)-2000]-N-tri(N-acetylgalactosamine), ammonium salt. CAS No. 2936651-86-2. Molecular formula: (C2H4O)nC97H180N9O38P.H3N. | |
| DSR-141562 | DSR-141562 is a potent and selective inhibitor of phosphodiesterases. DSR-141562 is a therapeutic candidate for positive, negative, and cognitive symptoms in schizophrenia. Synonyms: DSR 141562; DSR141562. Grade: 98% by HPLC. CAS No. 2007975-22-4. Molecular formula: C19H25F3N4O3. Mole weight: 414.4. | |
| DSR 6434 | DSR 6434 is a potent TLR7 agonist (EC50 = 7.2 nM). Synonyms: DSR 6434; DSR6434; DSR-6434; CHEMBL2315158; SCHEMBL1146577; SCHEMBL13448863; BDBM50425234; AKOS025147319; 1059070-10-8; 6-Amino-2-(butylamino)-9-[[6-[2-(dimethylamino)ethoxy]-3-pyridinyl]methyl]-7,9-dihydro-8H-purin-8-one. CAS No. 1059070-10-8. Molecular formula: C19H28N8O2. Mole weight: 400.48. | |
| DSRM-3716 | DSRM-3716 is a potent and selective inhibitor of SARM1 NADase with IC50 of 75 nM. Synonyms: Isoquinoline, 5-iodo-. Grade: 99%. CAS No. 58142-99-7. Molecular formula: C9H6IN. Mole weight: 255.06. | |
| DT-061 | DT-061 is orally bioavailable activator of protein phosphatase 2A (PP2A). PP2A inhibition is a druggable MEK inhibitor resistance mechanism in KRAS-mutant lung cancer cells. Synonyms: SMAP. CAS No. 1809427-19-7. Molecular formula: C25H23F3N2O5S. Mole weight: 520.52. | |
| dT-3'-PS Phosphoramidite | dT-3'-PS Phosphoramidite is a thymidine-derived phosphoramidite used for the synthesis of oligonucleotides containing a 3'-phosphorothioate (PS) linkage. The phosphorothioate modification replaces a non-bridging oxygen atom in the phosphate backbone with a sulfur atom, enhancing the nuclease resistance and biological stability of the resulting oligonucleotides. The thymine base is unmodified, ensuring normal base pairing during hybridization. This phosphoramidite is particularly valuable in therapeutic applications, such as antisense oligonucleotides and siRNA, where improved stability, enhanced pharmacokinetics, and resistance to enzymatic degradation are critical for effective performance. Synonyms: dT ThioPhosphamidite; Thymidine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-, 3'-[S-[2-(benzoylthio)ethyl] P-1-pyrrolidinylphosphonothioite]; Thymidine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-, 3'-[S-[2-(benzoylthio)ethyl] 1-pyrrolidinylphosphonothioite]; 5'-Dimethoxytrityl-2'-deoxyThymidine, 3'-[(β-thiobenzoylethyl)-(1-pyrrolidinyl)]-thiophosphoramidite; 5'-DMT-dT-3'-PS-Phosphoramidite. Grade: ≥90%. CAS No. 178272-24-7. Molecular formula: C44H48N3O8PS2. Mole weight: 841.97. | |
| D-Tagatose 1-phosphate | D-Tagatose 1-phosphate is a multifunctional compound for studying viral infections. It has exhibited its prowess as a pivotal intermediate in the synthesis of versatile chemical compounds, including potent antiviral compounds. CAS No. 63323-90-0. Molecular formula: C6H13O9P. Mole weight: 260.14. | |
| D-Tagatose-6-phosphate | D-Tagatose-6-phosphate is a remarkable compound, acting as a potent suppressor of carbohydrate metabolism-associated enzymes for diabetes research. Synonyms: D-Tagatofuranose 6-phosphate. CAS No. 67424-99-1. Molecular formula: C6H13O9P. Mole weight: 260.14. | |
| D-Tagatose-6-phosphate barium salt | D-Tagatose-6-phosphate barium salt. Molecular formula: C6H11BaO9P. Mole weight: 395.45. | |
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