BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| D-Tagatose-6-phosphate lithium salt | D-Tagatose-6-phosphate lithium salt is a bacterial strain that belongs to the group of polyols. D-Tagatose 6-phosphate is a substrate for tagatose-6-phosphate kinase which converts it into D-tagatose 1,6-bisphosphate with the transfer of a phosphate from ATP. Synonyms: D-Tagatofuranose 6-phosphate lithium salt. CAS No. 73544-42-0. Molecular formula: C6H13O9P.xLi. Mole weight: 260.14 (free acid). |  |
| D-Talitol | D-Talitol, a remarkably versatile sugar alcohol, finds extensive application as an excipient in diverse pharmaceutical formulations. Renowned for its profound efficacy in augmenting the flavor of oral drugs, it frequently serves as an agent to enhance the taste of chewable tablets and syrups to facilitate greater palatability. Moreover, D-Talitol assumes a pivotal role in the synthetic fabrication of numerous bioactive compounds, thereby showcasing its indispensable role in combating an assortment of diseases. Synonyms: D-Altritol. CAS No. 643-03-8. Molecular formula: C6H14O6. Mole weight: 182.17. | |
| D-Talitol-1,6-diphosphate | D-Talitol-1,6-diphosphate. | |
| D-Talono-1,4-lactone | D-Talono-1,4-lactone is an indispensable compound for the research of Alzheimer's, Parkinson's and diverse neurodegenerative maladies, intricately operating as a neuroactivity modifier. Synonyms: gamma-D-Galactonolactone; Gulono-1,4-lactone; D-Allonic acid gamma-lactone; D-Idonic acid, gamma-lactone; D-Galactonic acid, gamma-lactone; 5-(1,2-Dihydroxy-ethyl)-3,4-dihydroxy-dihydro-furan-2-one; gamma-Lactone of mannonic acid; D-Mannonic acid, gamma-lactone; D-Galactonic acid, gamma-lactone; 1,4-D-Gulonolactone; D-Allono-1,4-lactone; L-Gulonic acid g-lactone; Gulonic acid-1,4-lactone; D-Gulonic acid-1,4-lactone; Mannonic acid, D-; Galactonic acid, D-; glucono-1,4-lactone; 1,4-D-Mannonolactone; D-Galactono-gamma-lactone. CAS No. 23666-11-7. Molecular formula: C6H10O6. Mole weight: 178.14. | |
| D-Talose | D-Talose, a pivotal ingredient within the biomedical sphere, showcases its exceptional value in combating an array of ailments, including diabetes and cancer. Recognized for its medicinal prowess, this extensively examined compound exhibits captivating potential in pharmaceutical progress and the amelioration of maladies. Presenting a broad scope of applications, D-Talose stands as an indispensable force propelling biomedical exploration while simultaneously heightening the likelihood of positive prognoses for patients. Synonyms: D-(+)-Talose; aldehydo-D-talose; (2S,3S,4S,5R)-2,3,4,5,6-pentahydroxyhexanal; 8ZW23G7NVD; NSC-224293; EINECS 219-996-5; TALOSE, D-; UNII-8ZW23G7NVD; SCHEMBL37336; CHEBI:68461; GZCGUPFRVQAUEE-KAZBKCHUSA-N; DTXSID701318243; GEO-04668; MFCD00135834; AKOS024256927; HY-W145492; NSC 224293; CS-0214426; T72182; A877420; Q423195; W-202099; A02CA752-AB99-4BBF-84BA-31F5846CA891. CAS No. 2595-98-4. Molecular formula: C6H12O6. Mole weight: 180.16. | |
| DTBS-Gemcitabine | A derivative of Gemcitabine. Gemcitabine is a nucleoside analog used in chemotherapy to treat cancers including testicular cancer, breast cancer, ovarian cancer, non-small cell lung cancer, pancreatic cancer, and bladder cancer. Synonyms: 2'-Deoxy-3',5'-bis-O-[(1,1-dimethylethyl)dimethylsilyl]-2',2'-difluorocytidine; 4-Amino-1-((2R,4R,5R)-4-((tert-butyldimethylsilyl)oxy)-5-(((tert-butyldimethylsilyl)oxy)methyl)-3,3-difluorotetrahydrofuran-2-yl)pyrimidin-2(1H)-one; 3',5'-Bis-O-tert-butyldimethylsilyl-2'-deoxy-2',2'-difluorocytidine. Grade: ≥95%. CAS No. 688009-09-8. Molecular formula: C21H39N3O4F2Si2. Mole weight: 491.72. | |
| D-Thi(6)-ICA | D-Thi(6)-ICA is an impurity of Icatibant, which is a selective and specific antagonist of bradykinin B2 receptor. Synonyms: H-D-Arg-Arg-Pro-Hyp-Gly-D-2Thi-Ser-D-Tic-Oic-Arg-OH. Molecular formula: C59H89N19O13S. Mole weight: 1304.52. | |
| DTHIB | DTHIB is a direct and selective heat shock factor 1 (HSF1) inhibitor with a Kd of 160 nM. DTHIB strongly inhibits HSF1 cancer gene signature and prostate cancer cell proliferation. Synonyms: Urea, N-(4-chloro-3-nitrophenyl)-N'-(4-fluorophenyl)-. Grade: 98%. CAS No. 897326-30-6. Molecular formula: C13H9ClFN3O3. Mole weight: 309.68. | |
| dT-H-Phosphonate, TEA Salt | dT-H-Phosphonate, TEA Salt, is classified as a potent biomedical ingredient, used in research of anti-cancer regimens and nucleotide analog manipulation. Synonyms: 5'-Dimethoxytrityl-2'-deoxyThymidine, 3'-H-phosphonate, TEA salt. Molecular formula: C37H48N3O9P. Mole weight: 709.78. | |
| D-Thr(6)-Octreotide | D-Thr(6)-0ctreotide is an impurity of Octreotide, which is a synthetic long-acting cyclic octapeptide used as a more potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Synonyms: DPhe-Cys-Phe-DTrp-Lys-DThr-Cys-Thr-ol(Cys2&Cys7 bridge); D-Thr6-Octreotide; [D-Thr6]-Octreotide; D-Phe-c(Cys-Phe-D-Trp-Lys-D-Thr-Cys)-Thr-ol; H-D-Phe-Cys(1)-Phe-D-Trp-Lys-D-Thr-Cys(1)-Thr-ol; D-Phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-D-threonyl-L-cysteinyl-L-threoninol (2->8)-disulfide; D-Phenylalanyl-L-cystyl-L-phenylalanyl-D-tryptophyl-L-lysyl-D-threonyl-L-cystyl-L-threoninol (Disulfide Bridge between Cys2-Cys7); L-Cysteinamide, D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-D-threonyl-N-[2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2→7)-disulfide, [R-(R*,R*)]-; Octreotide impurity-10; H-D-Phe-Cys-Phe-D-Trp-Lys-D-Thr-Cys-Thr-ol (Disulfide bridge: Cys2-Cys7); L-Cysteinamide, D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-D-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2→7)-disulfide. Grade: ≥95%. CAS No. 87759-89-5. Molecular formula: C49H66N10O10S2. Mole weight: 1019.25. | |
| D-Thr(6)-Octreotide Acetate | D-Thr(6)-0ctreotide is an impurity of Octreotide, which is a synthetic long-acting cyclic octapeptide used as a more potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Synonyms: L-Cysteinamide, D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-D-threonyl-N-[2-hydroxy-1-(hydroxymethyl)propyl]-,cyclic (2→7)-disulfide, [R-(R*,R*)]-, acetate (salt) (9CI). Grade: 95%. CAS No. 87759-90-8. Molecular formula: C49H66N10O10S2.xC2H4O2. | |
| D-(+)-Threitol | D-(+)-Threitol is a multifaceted commodity extensively adopted realm, used for studying diverse afflictions such as diabetes, cardiovascular maladies and neurodegenerative states. Synonyms: (2R,3R)-1,2,3,4-Butanetetrol. Grade: ≥98%, ≥95%e.e. CAS No. 2418-52-2. Molecular formula: C4H10O4. Mole weight: 122.12. | |
| D-Threonic acid-1,4-lactone | D-Threonic acid-1,4-lactone is an eminent compound, finding its application in the research of diabetes and cardiovascular ailment. It is employed as an admirable antioxidant. Synonyms: D-Threono-1,4-lactone; D-threonolactone; threono-1,4-lactone; (3S,4R)-3,4-dihydroxydihydrofuran-2(3H)-one; D-Threonic acid γ-lactone. Grade: >97%. CAS No. 23732-41-4. Molecular formula: C4H6O4. Mole weight: 118.08. | |
| D-threo-PPMP hydrochloride | D-threo-PPMP is a glucosylceramide (GlyCer) synthetase inhibitor, which is the active enantiomer and enzymatic inhibitory component of the racemic DL-threo-PPMP. In MDCK kidney epithelial cells, D-threo-PPMP induces a 70% reduction in cell growth in vitro at 20 μM and significantly inhibits DNA synthesis at 3 μM. Synonyms: D-threo-1-phenyl-2-Palmitoylamino-3-morpholino-1-propanol; [R-(R*,R*)]-N-[2-hydroxy-1-(4-morpholinylmethyl)-2-phenylethyl]-hexadecanamide, monohydrochloride. Grade: ≥98%. CAS No. 139889-65-9. Molecular formula: C29H50N2O3·HCl. Mole weight: 511.2. | |
| D-Threose | D-Threose is an intriguing carbohydrate compound, exhibiting promising potential in studying both diabetes and obesity. Notably, its distinctive structural configuration renders it a viable building unit for drug synthesand design. Synonyms: D-(-)-Threose. CAS No. 95-43-2. Molecular formula: C4H8O4. Mole weight: 120.10. | |
| D-Thyroxine | D-Thyroxine is the dextrorotary isomer of thyroxine with antihyperlipidemic activity. It stimulates the formation of low-density lipoprotein (LDL) and increases the catabolism of LDL thereby leading to increased excretion of cholesterol and bile acids via the biliary route. It is released from thyroglobulin by proteolysis and secreted into the blood. It is one of the thyroid hormones involved in the maintenance of metabolic homeostasis and has been used to treat hyperlipidemia. It is used as an cholesterol-lowering drug but was pulled due to cardiac side-effects. It also increases hepatic lipase which in turn improves utilization of triglycerides, improving apolipoprotein E cholesterol particles. Uses: D-thyroxin is one of the thyroid hormones involved in the maintenance of metabolic homeostasis and has been used to treat hyperlipidemia. it is used as an cholesterol-lowering drug. Synonyms: Dextrothyroxine; Choloxin; Dextrothyroxinum; (R)-2-Amino-3-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)propanoic acid; Biotirmone; Debetrol; D-T4; O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-D-tyrosine. Grade: 95%. CAS No. 51-49-0. Molecular formula: C15H11I4NO4. Mole weight: 776.87. | |
| dT-Me Phosphonamidite | The dT-Me Phosphonamidite, a reagent of exemplary quality, is a favored instrument in the synthesis of modulated oligonucleotides that can be leveraged to study the intricacies of gene expression and regulation. Its utilization in the creation of therapeutic agents meant to combat genetic maladies - including but not limited to the likes of cancer and viral infections - is an established norm. Its unmatched construction renders it exceptionally stable whilst augmenting binding affinity, ultimately rendering it a precious asset in the realm of biomedicine. Synonyms: 5'-Dimethoxytrityl-2'-deoxyThymidine, 3'-[(methyl)-(N,N-diisopropyl)]-phosphonamidite. Molecular formula: C38H48N3O7P. Mole weight: 689.79. | |
| dT-Me Phosphoramidite | The dT-Me Phosphoramidite, a compound commonly utilized in the solid-phase synthesis of oligonucleotides incorporating methylated nucleosides, like 5-methylcytosine and N4-methylcytosine, has the propensity to improve the stability of RNA and DNA molecules. Therein lies the potential for a game-changing effect on the development of innovative treatments for challenging diseases such as cancer, viral infections or genetic disorders. Synonyms: 5'-Dimethoxytrityl-2'-deoxyThymidine, 3'-[(methyl)-(N,N-diisopropyl)]-phosphoramidite. CAS No. 84416-85-3. Molecular formula: C38H48N3O8P. Mole weight: 705.79. | |
| DTP3 | DTP3 is a selective GADD45β/MKK7 inhibitor, which interacts with and caused a significant conformational change of GADD45β/MKK7 complex in a dose dependent way, as well as of the isolated MKK7 protein. Synonyms: (2R)-2-[[(2R)-2-acetamido-3-(4-hydroxyphenyl)propanoyl]amino]-N-[(2R)-1-amino-1-oxo-3-phenylpropan-2-yl]-5-(diaminomethylideneamino)pentanamide. Grade: ≥98%. CAS No. 1809784-29-9. Molecular formula: C26H35N7O5. Mole weight: 525.6. | |
| DTP348 | DTP348 is an oral dual CAIX inhibitor/ radiosensitizer. DTP348 is an oral dual drug with two mechanisms of action: (1) carbonic anhydrase IX inhibitor which acidifies the intracellular pH through the sulfamide components; (2) radio sensitizer of hypoxic cells through its 5-nitroimidazole moiety. Synonyms: DTP 348; DTP-348; 2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethylsulfamide; 1-(2-Sulfamidoethyl)-2-methyl-5-nitroimidazole. CAS No. 1383370-92-0. Molecular formula: C6H11N5O4S. Mole weight: 249.24. | |
| DTP3 TFA | DTP3 is a selective GADD45β/MKK7 inhibitor, which interacts with and caused a significant conformational change of GADD45β/MKK7 complex in a dose dependent way, as well as of the isolated MKK7 protein. Molecular formula: C28H36F3N7O7. Mole weight: 639.62. | |
| dT-PACE Phosphoramidite | dT-PACE Phosphoramidite is a vital constituent within the biomedical arena, serving as a pivotal recompound solely dedicated to the solid-phase synthesis of oligonucleotides. Proficiently facilitating the assimilation of dT-PACE is a distinctly altered nucleoside analog, into the intricate framework of oligonucleotide chains. Synonyms: DNA T PACE amidite; Thymidine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-, 3'-[P-[2-(2-cyano-1,1-dimethylethoxy)-2-oxoethyl]-N,N-bis(1-methylethyl)phosphonamidite]; 5'-Dimethoxytrityl-2'-deoxyThymidine, 3'-O-(N,N-diisopropylamino)-phosphinyl-1,1-dimethyl-2-cyanoethyl acetate. Grade: ≥95%. CAS No. 411234-18-9. Molecular formula: C44H55N4O9P. Mole weight: 814.90. | |
| DTPA Impurity 1 | DTPA Impurity. Synonyms: 2-[bis[2-[bis(cyanomethyl)amino]ethyl]amino]acetonitrile; Acetonitrile, 2,2',2'',2'''-[[(cyanomethyl)imino]bis(2,1-ethanediylnitrilo)]tetrakis-; NSC231420; SCHEMBL11414953; DTXSID30310725; NSC-231420; 2,2',2'',2''',2''''-(Ethane-1,2-diylnitrilo)pentaacetonitrile. Grade: > 95%. CAS No. 27825-74-7. Molecular formula: C14H18N8. Mole weight: 298.35. | |
| DTPA (Pentetic Acid) | Pentetic acid is mainly used as a chelating agent in the preparation of imaging and as a contrast agent for radionuclides and magnetic resonance imaging. Uses: Chelating agents. Synonyms: N,N-Bis[2-[bis(carboxymethyl)amino]ethyl]glycine; 1,1,4,7,7-Diethylenetriaminepentaacetic Acid; 3,6,9-tris(carboxymethyl)-3,6,9-Triazaundecanedioic Acid; 2,2',2'',2'''-[[(carboxymethyl)imino]bis(2,1-ethanediylnitrilo)]tetrakisacetic Acid; DETP; DETPA; DPTA; Detapac; Detarex; Diethylenetriamine-N,N,N',N'',N''-pentaacetic Acid; Diethylenetriaminepentaacetic Acid; NSC 7340; Pentacarboxymethyl diethylenetriamine; Pentetic Acid; [[(Carboxymethyl)imino]bis(ethylenenitrilo)]tetraacetic Acid. Grade: >95%. CAS No. 67-43-6. Molecular formula: C14H23N3O10. Mole weight: 393.35. | |
| dTpCpp | dTpCpp is an extensively applied nucleotide analogue domain, exbibiting remarkable prospects in nucleic acid synthesand modification. The ingenious usage of dTpCpp extends to genetic investigations concerning the precise labeling of DNA and RNA at specific sites, thereby facilitating intricate investigations into replication, transcription and translation processes. Synonyms: dTMPCPP; 2'-Deoxythymidine-5'-[(α,β)-methyleno]triphosphate, Sodium salt. Grade: ≥ 95 % by HPLC. Molecular formula: C11H19N2O13P3(free acid). Mole weight: 480.20 (free acid). | |
| dTpNHpp | dTpNHpp, a nucleotide analog employed in biomedical research, represents an intriguing prospect as an anti-cancer agent. As a potent and selective inhibitor of polo-like kinases (Plks), preclinical studies reveal its potential to bring about cell cycle arrest and stifle tumor growth. In fact, investigations into cancer therapy have even explored its viability in targeted drug delivery systems. Synonyms: dTMPNPP; 2'-Deoxythymidine-5'-[(α,β)-imido]triphosphate, Sodium salt. Grade: ≥ 95 % by HPLC. CAS No. 183584-80-7. Molecular formula: C10H14Na4N3O13P3. Mole weight: 569.14. | |
| DTR-I | DTR-I is one of Tetrabenazine intermediates. Tetrabenazine is a VMAT-inhibitor used for treatment of hyperkinetic movement disorder. It is a monoamine-depleting and a dopamine-receptor-blocking drug and is an effective and safe drug for the treatment of a variety of hyperkinetic movement disorders. Synonyms: (3R,11bR)-rel-1,3,4,6,7,11b-Hexahydro-9,10-dihydroxy-3-(2-methylpropyl)-2H-benzo[a]quinolizin-2-one; 2H-Benzo[a]quinolizin-2-one, 1,3,4,6,7,11b-hexahydro-9,10-dihydroxy-3-(2-methylpropyl)-, (3R,11bR)-rel-. Grade: ≥95%. CAS No. 2220998-55-8. Molecular formula: C17H23NO3. Mole weight: 289.37. | |
| D-Trp(25)-Semaglutide | D-Trp(25)-Semaglutide is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: D-Trp-25-Semaglutide. Grade: 95%. Molecular formula: C187H291N45O59. Mole weight: 4113.64. | |
| D-Trp5-Eptifibatide | An impurity of Eptifibatide. Eptifibatide is a glycoprotein IIb/IIIa inhibitor used primarily to prevent blood clots in patients with acute coronary syndromes (ACS) and during percutaneous coronary interventions (PCI). Synonyms: Mpr-Har-Gly-Asp-DTrp-Pro-Cys-NH2(Mpr1&Cys7 bridge); Mpr-Har-GD-DTrp-PC-NH2(Mpr&Cys bridge); deamino-Cys-hArg-Gly-Asp-D-Trp-Pro-Cys-NH2 (Disulfide bridge: Cys1-Cys7); Deamino-cysteinyl-L-homoarginyl-glycyl-L-alpha-aspartyl-D-tryptophyl-L-prolyl-L-cysteinamide (1->7)-disulfide; D-Trp(5) Eptifibatide; [D-Trp]5-Eptifibatide; [D-Trp5]-Eptifibatide; 5-D-Trp Eptifibatide. Grade: ≥95%. Molecular formula: C35H49N11O9S2. Mole weight: 831.97. | |
| dT-Thiophosphoramidite | dT-Thiophosphoramidite, a chemical compound utilized in the synthetic process of oligonucleotides, characterized as a class of biomolecules with vast implications in the biomedical arena, specifically for diagnostics, gene therapy, and drug development, adds to the the structural and functional modification of oligonucleotides as an indispensable building block. Synonyms: 5'-Dimethoxytrityl-2'-deoxyThymidine, 3'-[(ß-thiobenzoylethyl)-(1-pyrrolidinyl)]-thiophosphoramidite; 5'-O-(4,4'-Dimethoxytrityl)-3'-O-[pyrrolizino[[2-(benzoylthio)ethyl]thio]phosphino]thymidine. Molecular formula: C44H48N3O8PS2. Mole weight: 841.97. | |
| dTTPαS | dTTPαS is a modified nucleotide analogue used in enzymology and molecular biology research. It can be incorporated into DNA sequences during polymerase chain reaction (PCR) and is commonly used in site-directed mutagenesis studies. It has also been used in the study of DNA replication and repair mechanisms. Synonyms: 2'-Deoxythymidine-(α-thio)-triphosphate, Sodium salt (1 : 1 Mixture of Rp and Sp isomers). Grade: ≥ 95 % by HPLC. CAS No. 99749-43-6. Molecular formula: C10H17N2O13P3S.4Na. Mole weight: 586.19. | |
| dTTP solution - Lithium Salt | dTTP could be used in the studies of DNA labeling reactions, polymerase chain reaction and sequencing/cycle sequencing analysis. Grade: ≥ 99 % by HPLC. Molecular formula: C10H17N2O14P3·xLi. Mole weight: 482.17 (free acid). | |
| D-Turanose | D-Turanose, an exceptional carbohydrate embraced in the realm of biomedical industry, entices scientific intrigue. Esteemed for its pharmacological possibilities, this marvel has garnered profound attention for drug delivery systems and the amelioration of ailments such as diabetes and obesity. Its distinctive architecture empowers potent drug stability as well as meticulous release, thus rendering it an invaluable constituent within pharmaceutical formulations. Moreover, D-Turanose exhibits propitious prospects in tempering glycemic indices and orchestrating weight management, constituting a propelling contender for therapeutic interventions. Synonyms: Turanose; 3-O-(a-D-Glucopyranosyl)-D-fructose; 3-(α-D-Glucosido)-D-fructose; 3-O-α-D-Glucopyranosyl-D-fructose; D-(+)-Turanose; NSC 1222; (3S,4R,5R)-1,4,5,6-Tetrahydroxy-3-(((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexan-2-one. CAS No. 547-25-1. Molecular formula: C12H22O11. Mole weight: 342.30. | |
| D-Tyr(13)-Semaglutide | D-Tyr(13)-Semaglutide is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: D-[Tyr]-13-Semaglutide. Grade: 95%. Molecular formula: C187H291N45O59. Mole weight: 4113.64. | |
| D-Tyr(2)-AVP | D-Tyr(2)-AVP is an impurity of Vasopressin, which is an antidiuretic hormone secreted from the posterior pituitary. Synonyms: D-Tyr-Vasopressin; D-Tyr-AVP; Vasopressin, 2-D-tyrosine-8-L-arginine-; H-Cys-D-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly-NH2 (Disulfide bridge: Cys1-Cys6); L-cysteinyl-D-tyrosyl-L-phenylalanyl-L-glutaminyl-L-asparagyl-L-cysteinyl-L-prolyl-L-arginyl-glycinamide (1->6)-disulfide. CAS No. 66513-06-2. Molecular formula: C46H65N15O12S2. Mole weight: 1084.24. | |
| D-Tyr5-Cetrorelix | An impurity of Cetrorelix. Cetrorelix is a gonadotropin-releasing hormone (GnRH) antagonist used primarily in reproductive medicine and oncology. It works by competitively binding to GnRH receptors, thereby inhibiting the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), which in turn prevents ovulation and reduces the production of sex steroids. Synonyms: Ac-D2Nal-D4Cpa-D3Pal-Ser-DTyr-DCit-Leu-Arg-Pro-DAla-NH2; Ac-D-2Nal-D-Phe(4-Cl)-D-3Pal-Ser-D-Tyr-D-Cit-Leu-Arg-Pro-D-Ala-NH2; N-Acetyl-3-(2-naphthyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridyl)-D-alanyl-L-seryl-D-tyrosyl-D-citrullyl-L-leucyl-L-arginyl-L-prolyl-D-alaninamide; [D-Tyr]5-Cetrorelix; [D-Tyr5]-Cetrorelix; D-Tyr(5)-Cetrorelix. Grade: ≥95%. CAS No. 3031679-86-1. Molecular formula: C70H92ClN17O14. Mole weight: 1431.06. | |
| DU125530 | DU125530 is a selective 5-HT1A receptor antagonist (Ki = 0.7 nM). DU125530 has the potential to be used in the treatment of anxiety, depression and psychiatric disorders. Synonyms: DU-125530; DU125530; DU 125530; 2-[4-[4-(7-chloro-2,3-dihydro-1,4-benzodioxin-5-yl)piperazin-1-yl]butyl]-1,1-dioxo-1,2-benzothiazol-3-one. Grade: 99%. CAS No. 161611-99-0. Molecular formula: C23H26ClN3O5S. Mole weight: 491.99. | |
| dU-3'-PS Phosphoramidite | dU-3'-PS Phosphoramidite is a deoxyuridine-derived phosphoramidite designed for the synthesis of oligonucleotides containing a 3'-phosphorothioate (PS) linkage. The 3'-PS modification replaces a non-bridging oxygen atom in the phosphate group with a sulfur atom, significantly enhancing the nuclease resistance and biological stability of the resulting oligonucleotides. The uracil base remains unmodified, maintaining standard base-pairing properties during hybridization. This phosphoramidite is particularly valuable in therapeutic oligonucleotide applications, such as antisense oligonucleotides and siRNA, where improved stability, resistance to enzymatic degradation, and extended biological activity are critical. Synonyms: S-(2-(((((2R,3S,5R)-2-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl)oxy)(pyrrolidin-1-yl)phosphaneyl)thio)ethyl) benzothioate; dU ThioPhosphamidite; Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-, 3'-[S-[2-(benzoylthio)ethyl] P-1-pyrrolidinylphosphonothioite]; Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-, 3'-[S-[2-(benzoylthio)ethyl] 1-pyrrolidinylphosphonothioite]; 5'-Dimethoxytrityl-2'-deoxyUridine, 3'-[(β-thiobenzoylethyl)-(1-pyrrolidinyl)]-thiophosphoramidite; 5'-DMT-dU-3'-PS-Phosphoramidite. Grade: ≥90%. Molecular formula: C43H46N3O8PS2. Mole weight: 827.95. | |
| Dual AChE-MAO B-IN-1 | Dual AChE-MAO B-IN-1 is an orally bioavailable CNS-permeant potent inhibitor of both human AChE (IC50 = 550 nM) and MAO B (IC50 = 8.2 nM). Dual AChE-MAO B-IN-1 has been used as a safe and metabolically stable neuroprotective agent, devoid of cytochrome liability. Molecular formula: C23H25F2NO4. Mole weight: 417.45. | |
| DUBs-IN-1 | DUBs-IN-1 is a potent deubiquitinase enzyme inhibitor for USP7/USP8. Synonyms: DUBs-IN-1; DUBs IN 1. Grade: >98%. CAS No. 924296-18-4. Molecular formula: C20H11N5O. Mole weight: 337.33. | |
| DUBs-IN-2 | DUBs-IN-2 is a potent deubiquitinase enzyme inhibitor for USP7/USP8. Synonyms: DUBs IN 2. Grade: >98%. CAS No. 924296-19-5. Molecular formula: C15H9N5O. Mole weight: 275.26. | |
| DUBs-IN-3 | DUBs-IN-3 is a potent deubiquitinase enzyme inhibitor for USP8. It is 30 fold selectivity over USP7. Synonyms: DUBs-IN-3; DUBs IN 3. Grade: >98%. CAS No. 924296-17-3. Molecular formula: C16H9N5O. Mole weight: 287.28. | |
| Ducheside A pentaacetate | Ducheside A pentaacetate. | |
| dU-CPG 1000 | dU-CPG 1000 is a remarkable synthetic modified nucleotide. With improved stability and effectiveness of nucleic acids, dU-CPG 1000 is more effective in fighting a range of diseases such as cancer and viral infections. Synonyms: 5'-Dimethoxytrityl-2'-deoxyUridine, 3'-succinoyl-long chain alkylamino-CPG 1000. | |
| dU-CPG 500 | dU-CPG 500, a synthetic oligonucleotide, is a robust immunostimulatory agent that has shown promising results in augmenting the immune response to vaccines and cancer immunotherapy. Additionally, its potential as a therapeutic agent to treat autoimmune and inflammatory diseases is the subject of ongoing investigations in the scientific community. Its versatility in these contexts attests to its potency as an indispensable tool for researchers and clinicians alike. Synonyms: 5'-Dimethoxytrityl-2'-deoxyUridine, 3'-succinoyl-long chain alkylamino-CPG 500. | |
| D-[UL-13C6,15N]Glucosamine HCl | D-[UL-13C6,15N]Glucosamine HCl. Molecular formula: [13C]6H13[15N]O5·HCl. Mole weight: 222.58. | |
| D-[UL-13C6]Fructose 1-phosphate disodium salt | D-[UL-13C6]Fructose 1-phosphate disodium salt. | |
| D-[UL-13C6]fructose 6-phosphate (disodium salt, hydrate) | D-[UL-13C6]fructose 6-phosphate (disodium salt, hydrate). Molecular formula: 13C6H11Na2O9P·(H2O)x. Mole weight: 310.05 (anhydrous basis). | |
| D-[UL-13C6]Fructose 6-phosphate disodium salt, hydrate | D-[UL-13C6]Fructose 6-phosphate disodium salt, hydrate. | |
| D-[UL-13C6]Glucosamine HCl | D-[UL-13C6]Glucosamine HCl is a distinctive modified version of glucosamine, prevalently prescribed for the research of osteoarthritis. The incorporation of stable carbon isotopes within this compound unequivocally elicits indispensable contributions towards metabolic investigation and analysis pertaining to pharmaceutical drug assimilation. Molecular formula: [13C]6H13NO5.HCl. Mole weight: 221.59. | |
| D-[UL-2H6]xylose | D-[UL-2H6]xylose. Molecular formula: C52H6H4O5. Mole weight: 156.17. | |
| D-[UL-2H7]fructose | D-[UL-2H7]fructose. Molecular formula: C62H7H5O6. Mole weight: 187.2. | |
| D-[UL-2H8]glucitol | D-[UL-2H8]glucitol. Synonyms: D-[UL-2H8]sorbitol. Molecular formula: C62H8H6O6. Mole weight: 190.22. | |
| Dulcitol | Dulcitol is a saccharitol synthesized from diverse botanical origins, manifesting imbued potential for pharmaceutical and nutraceutical applications. Synonyms: Galactitol. CAS No. 608-66-2. Molecular formula: C6H14O6. Mole weight: 182.17. | |
| Duloxetine | Duloxetine is a serotonin-norepinephrine reuptake inhibitor (Ki=4.6 nM), used for major depressive disorder, generalized anxiety disorder, fibromyalgia and neuropathic pain. Uses: Adrenergic uptake inhibitors; analgesics; antidepressive agents; dopamine uptake inhibitors; serotonin uptake inhibitors. Synonyms: (S)-Duloxetine; Cymbalta; Yentreve; (S)-N-Methyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amine; LY 248686; Xeristar; LY248686; LY-248686; (γS)-N-Methyl-γ-(1-naphthalenyloxy)-2-thiophenepropanamine; (+)-(S)-N-Methyl-γ-(1-naphthyloxy)-2-thiophenepropylamine; (3S)-N-Methyl-3-(1-naphthyloxy)-3-(2-thienyl)-1-propanamine. Grade: >98%. CAS No. 116539-59-4. Molecular formula: C18H19NOS. Mole weight: 297.41. | |
| Duloxetine EP Impurity A | Duloxetine HCl R-Isomer. Uses: Analgesics. Synonyms: (3R)-N-Methyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amine HCl. Grade: > 95%. CAS No. 910138-96-4. Molecular formula: C18H19NOS·HCl. Mole weight: 333.882. | |
| Duloxetine EP Impurity C HBr | Duloxetine Impurity. Grade: > 95%. CAS No. 949096-01-9. Molecular formula: C18H19NOS·HBr. Mole weight: 378.333. | |
| Duloxetine EP Impurity E | An impurity of the antidepressant Duloxetine. Synonyms: 1-(3-(Methylamino)thiophen-2-yl)propyl)naphthalen-2-ol. Grade: > 95%. CAS No. 1346599-09-4. Molecular formula: C18H19NOS. Mole weight: 297.41. | |
| Duloxetine EP Impurity F (Duloxetine 3-Acetyl) HCl | An isomeric impurity of the antidepressant Duloxetine. Synonyms: (S)-N-Methyl-3-(naphthalen-1-yloxy)-3-(thiophen-3-yl)propan-1-amine Hydrochloride. Grade: > 95%. CAS No. 1104890-90-5. Molecular formula: C18H19NOS·HCl. Mole weight: 333.88. | |
| Duloxetine EP Impurity F Hydrochloride | Duloxetine EP Impurity F Hydrochloride is an impurity of Duloxetine, which is a serotonin-norepinephrine reuptake inhibitor used to treat major depressive disorder, generalized anxiety disorder, fibromyalgia, neuropathic pain and central sensitization. Synonyms: (S)-N-Methyl-3-(naphthalen-1-yloxy)-3-(thiophen-3-yl)propan-1-amine hydrochloride; Duloxetine Related Compound F. Grade: 98%. CAS No. 2748376-86-3. Molecular formula: C18H20ClNOS. Mole weight: 333.88. | |
| Duloxetine Impurity A | A degradation product of Duloxetine. Synonyms: N-Methyl-N-[(3S)-3-(1-naphthalenyloxy)-3-(2-thienyl)propyl]carbamic Acid Phenyl Ester. Grade: > 95%. CAS No. 947686-09-1. Molecular formula: C25H23NO3S. Mole weight: 417.52. | |
| Duloxetine impurity (alpha-hydroxy) | Duloxetine impurity. Grade: > 95%. CAS No. 940291-11-2. Molecular formula: C18H19NOS. Mole weight: 297.42. | |
| Duloxetine Maleate | Duloxetine Maleate is a serotonin-norepinephrine reuptake inhibitor used to treat major depressive disorder, generalized anxiety disorder, fibromyalgia, neuropathic pain and central sensitization. Synonyms: (γS)-N-Methyl-γ-(1-naphthalenyloxy)-2-thiophenepropanamine Maleate; (+)-(S)-N-Methyl-γ-(1-naphthyloxy)-2-thiophenepropylamine Maleate; LY-248686 Maleate; (S)-N-methyl-γ-(1-naphthalenyloxy)-2-thiophenepropanamine (Z)-2-Butenedioate; (3S)-N-Methyl-3-(1-naphthyloxy)-3-(2-thienyl)-1-propanamine (2Z)-2-butenedioate (1:1); 2-Thiophenepropanamine, N-methyl-γ-(1-naphthalenyloxy)-, (γS)-, (2Z)-2-butenedioate (1:1). Grade: ≥95%. CAS No. 116817-86-8. Molecular formula: C22H23NO5S. Mole weight: 413.49. | |
| Duloxetine N-methyl Impurity | A duloxetine impurity. Synonyms: (S)-N,N-Dimethyl-3-(1-naphthalenyloxy)-3-(2-thienyl)propanamine Ethanedioate; (γS)-N,N-Dimethyl-γ-(1-naphthalenyloxy)-2-thiophenepropanamine Ethanedioate. Grade: > 95%. CAS No. 132335-47-8. Molecular formula: C19H21NOS·C2H2O4. Mole weight: 401.48. | |
| Duloxetine Related Compound H | Duloxetine Related Compound H is an impurity of Duloxetine, which is a serotonin-norepinephrine reuptake inhibitor used to treat major depressive disorder, generalized anxiety disorder, fibromyalgia, neuropathic pain and central sensitization. Synonyms: (S)-Duloxetine Succinamide; 4-[Methyl[(3S)-3-(1-naphthalenyloxy)-3-(2-thienyl)propyl]amino]-4-oxobutanoic Acid. Grade: 98%. CAS No. 199191-66-7. Molecular formula: C22H23NO4S. Mole weight: 397.49. | |
| DuP 105 | DuP 105, an orally active oxazolidinone, is a new synthetic antimicrobial agent with activity against gram-positive bacteria. Synonyms: Dup-105; DuP105; 4-Methylsulfinylphenyloxooxazolidinylmethylacetamide; Acetamide, N-((3-(4-(methylsulfinyl)phenyl)-2-oxo-5-oxazolidinyl)methyl)-, (S)-; (S)-N-[3-(4-Methanesulfinyl-phenyl)-2-oxo-oxazolidin-5-ylmethyl]-acetamide. Grade: ≥95%. CAS No. 96800-41-8. Molecular formula: C13H16N2O4S. Mole weight: 296.34. | |
| DuP-697 | DuP-697 is a selective COX-2 inhibitor. Synonyms: DuP-697; DuP 697; DuP697; S-6907; S 6907; S6907; BFMT; 5-bromo-2-(4-fluorophenyl)-3-(4-(methylsulfonyl)phenyl)-thiophene. CAS No. 88149-94-4. Molecular formula: C17H12BrFO2S2. Mole weight: 411.3. | |
| dUpCp | dUpCp, a nucleoside analogue hailed for its therapeutic potential in treating viral infections such as hepatitis C and HIV, has garnered attention for its capacity to inhibit viral replication and to stymie further infection. What's more, this potent analogous substance holds great promise in fighting cancer, with studies demonstrating its propensity to selectively trigger apoptosis in cancer cells. Although the ramifications of its usage as an antitumor agent call for further inquiry into its efficacy, it's an exciting prospect indeed. Synonyms: dUMPCP; 2'-Deoxyuridine-5'-[(α,β)-methyleno]diphosphate, Sodium salt. Grade: ≥ 95 % by HPLC. Molecular formula: C10H16N2O10P2(free acid). Mole weight: 386.19 (free acid). | |
| dUpCpp | dUpCpp - a chemical compound utilized in the field of biomedical research - holds promising potential as an enzyme activator which facilitates DNA and RNA replication. By augmenting the function of polymerases essential for viral replication, this unique substance presents a promising target for antiviral drug development. Furthermore, dUpCpp has been utilized to probe and unravel the mechanisms underlying the polymerization of DNA and RNA in a spectrum of systems. Synonyms: dUMPCPP; 2'-Deoxyuridine-5'-[(α,β)-methyleno]triphosphate, Sodium salt. Grade: ≥ 95 % by HPLC. CAS No. 170428-84-9. Molecular formula: C10H17N2O13P3.xNa. Mole weight: 466.17 (free acid). | |
| Dupilumab | Dupilumab, marketed under the brand name Dupixent, is a monoclonal antibody used to treat several chronic inflammatory conditions. It works by inhibiting the signaling of interleukin-4 (IL-4) and interleukin-13 (IL-13), which are cytokines involved in the inflammatory response. Dupilumab is approved for the treatment of several conditions, including, atopic dermatitis, asthma, chronic rhinosinusitis with nasal polyps (CRSwNP), and eosinophilic esophagitis. Synonyms: Immunoglobulin, anti-(human interleukin 4 receptor α) (human REGN668 heavy chain), disulfide with human REGN668 κ-chain, dimer; Dupixent; REGN 668; SAR 231893. CAS No. 1190264-60-8. | |
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