BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Biotin-PEG6-azide | Biotin-PEG6-azide is a polyethylene glycol (PEG)-based PROTAC linker. Biotin-PEG6-azide can be used in the synthesis of a series of PROTACs. CAS No. 1085938-09-5. Molecular formula: C24H44N6O8S. Mole weight: 576.71. |  |
| Biotin-PEG6-Boc | Biotin-PEG6-Boc is a polyethylene glycol (PEG)-based PROTAC linker. Biotin-PEG6-Boc can be used in the synthesis of a series of PROTACs. CAS No. 1352814-07-3. Molecular formula: C29H53N3O10S. Mole weight: 635.81. | |
| Biotin-PEG6-hydrazide | Biotin-PEG6-hydrazide is a biotin-PEG derivative for biotinylation. The biotin group serves as an affinity label towards the proteins avidin and streptavidin. Synonyms: (+)-Biotin-PEG6-hydrazide. Grade: >95%. Molecular formula: C25H47N5SO9. Mole weight: 593.73. | |
| Biotin-PEG6-NH-Boc | Biotin-PEG6-NH-Boc is a Biotin compound with a Boc protected amine moiety. Please contact us for GMP-grade inquiries. Synonyms: Biotin-PEG6-NH-Boc; 1292268-20-2; HY-W190945; BP-23614; CS-0254648; tert-butyl N-[2-[2-[2-[2-[2-[2-[2-[5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoylamino]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl]carbamate. Grade: 0.98. CAS No. 1292268-20-2. Molecular formula: C29H54N4O10S. Mole weight: 650.8. | |
| Biotin-PEG6-NH-Mal | Biotin-PEG6-Mal is a polyethylene glycol (PEG)-based PROTAC linker. Biotin-PEG6-Mal can be used in the synthesis of a series of PROTACs. Synonyms: (+)-Biotin-PEG6-NH-Mal; Biotin-PEG6-Mal; Biotin-PEG6-Maleimide; (+)-Biotin-PEG6-Maleimide. Grade: >97%. CAS No. 1808990-66-0. Molecular formula: C31H51N5O11S. Mole weight: 701.83. | |
| Biotin-PEG6-NHS ester | Biotin-PEG6-NHS ester is a polyethylene glycol (PEG)-based PROTAC linker. Biotin-PEG6-NHS ester can be used in the synthesis of a series of PROTACs. Synonyms: (+)-Biotin-PEG6-NHS Ester. Grade: >97%. CAS No. 2055045-04-8. Molecular formula: C29H48N4O12S. Mole weight: 676.78. | |
| Biotin-PEG6-Thalidomide | Biotin-PEG6-Thalidomide is a polyethylene glycol (PEG)-based PROTAC linker. Biotin-PEG6-Thalidomide can be used in the synthesis of a series of PROTACs. CAS No. 2144775-48-2. Molecular formula: C37H53N5O12S. Mole weight: 791.91. | |
| Biotin-PEG7-amine | Biotin-PEG7-amine is a polyethylene glycol (PEG)-based PROTAC linker. Biotin-PEG7-amine can be used in the synthesis of a series of PROTACs. Synonyms: Biotin-PEG7-NH2. Grade: >95%. CAS No. 1334172-76-7. Molecular formula: C26H50N4O9S. Mole weight: 594.76. | |
| Biotin-PEG7-azide | Biotin-PEG7-azide is a polyethylene glycol (PEG)-based PROTAC linker. Biotin-PEG7-azide can be used in the synthesis of a series of PROTACs. CAS No. 1334172-75-6. Molecular formula: C26H48N6O9S. Mole weight: 620.76. | |
| Biotin-PEG7-C2-NH-Vidarabine-S-CH3 | Biotin-PEG7-C2-NH-Vidarabine-S-CH3 is a PEG-based linker that incorporates adenosine analog Vidarabine. Vidarabine is an antiviral agent which is active against herpes simplex and varicella zoster viruses. Synonyms: Biotin-PEG7-C2-NH-Vidarabine-S-CH3|HY-145248|CS-0370383. Grade: >98%. Molecular formula: C37H62N8O12S2. Mole weight: 875.06. | |
| Biotin-PEG7-C2-S-Vidarabine | Biotin-PEG7-C2-S-Vidarabine is a PEG-based linker that incorporates adenosine analog Vidarabine. Vidarabine is an antiviral agent which is active against herpes simplex and varicella zoster viruse. Synonyms: Biotin-PEG7-C2-S-Vidarabine|HY-145247|CS-0370381. Grade: >98%. Molecular formula: C36H60N8O12S2. Mole weight: 861.04. | |
| Biotin-PEG7-thiourea | Biotin-PEG7-thiourea is a polyethylene glycol (PEG)-based PROTAC linker. Biotin-PEG7-thiourea can be used in the synthesis of a series of PROTACs. CAS No. 2353409-59-1. Molecular formula: C27H51N5O9S2. Mole weight: 653.85. | |
| Biotin-PEG8-acid | Biotin-PEG8-acid is a polyethylene glycol (PEG)-based PROTAC linker. Biotin-PEG8-acid can be used in the synthesis of a series of PROTACs. CAS No. 2143964-62-7. Molecular formula: C29H53N3O12S. Mole weight: 667.81. | |
| Biotin-PEG8-alcohol | Biotin-PEG8-alcohol is a biotin-PEG derivative for biotinylation. The biotin group serves as an affinity label towards the proteins avidin and streptavidin. Synonyms: (+)-Biotin-PEG8-OH; (+)-Biotin-PEG8-alcohol; Biotin-PEG8-OH. Grade: >97%. Molecular formula: C26H49N3O10S. Mole weight: 595.75. | |
| Biotin-PEG8-alkyne | Biotin-PEG8-alkyne. Synonyms: Biotin-PEG8-Alkyne; HY-156379; CS-0900005; 2143968-80-1; N-(3,6,9,12,15,18,21,24-Octaoxaheptacos-26-yn-1-yl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide. Grade: 0.98. CAS No. 2143968-80-1. Molecular formula: C29H51N3O10S. Mole weight: 633.8. | |
| Biotin-PEG8-amine | Biotin-PEG8-amine is a polyethylene glycol (PEG)-based PROTAC linker. Biotin-PEG8-amine can be used in the synthesis of a series of PROTACs. CAS No. 2183447-27-8. Molecular formula: C28H54N4O10S. Mole weight: 638.81. | |
| Biotin-PEG8-azide | Biotin-PEG8-azide is click chemistry reagent for biotinylation of macromolecule Please contact us for GMP-grade inquiries. Synonyms: Biotin-PEG8-azide; SCHEMBL21150837; 2363756-34-5; N-(26-Azido-3,6,9,12,15,18,21,24-octaoxahexacosyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide; BP-25110. Grade: 0.98. CAS No. 2363756-34-5. Molecular formula: C28H52N6O10S. Mole weight: 664.8. | |
| Biotin-PEG8-Bromide | Biotin-PEG8-Bromide. Grade: 0.97. Molecular formula: C28H52BrN3O10S. Mole weight: 702.7. | |
| Biotin-PEG8-DBCO | Biotin-PEG8-DBCO. Synonyms: Biotin-PEG8-DBCO; BP-25505. Grade: 0.98. Molecular formula: C47H67N5O12S. Mole weight: 926.1. | |
| Biotin-PEG8-NHS ester | Biotin-PEG8-NHS ester is a biotin-PEG derivative for biotinylation. The biotin group serves as an affinity label towards the proteins avidin and streptavidin. Synonyms: (+)-Biotin-PEG8-NHS Ester. Grade: >97%. Molecular formula: C33H56N4SO14. Mole weight: 764.88. | |
| Biotin-PEG8-propionic acid | Biotin-PEG8-propionic acid is a biotin-PEG derivative for biotinylation. The biotin group serves as an affinity label towards the proteins avidin and streptavidin. Synonyms: (+)-Biotin-PEG8-CH2CH2COOH; (+)-Biotin-PEG8-propionic acid; Biotin-PEG8-CH2CH2COOH. Grade: >97%. Molecular formula: C29H53N3SO12. Mole weight: 667.81. | |
| Biotin-PEG8-TCO | Biotin-PEG8-TCO. Synonyms: Biotin-PEG8-TCO; BP-28222. Grade: 0.95. Molecular formula: C37H66N4O12S. Mole weight: 791. | |
| Biotin-PEG8-TFP ester | Biotin-PEG8-TFP ester. Grade: 0.95. Molecular formula: C35H53F4N3O12S. Mole weight: 815.9. | |
| Biotin-PEG8-Vidarabine | Biotin-PEG8-Vidarabine is a PEG-based linker that incorporates adenosine analog Vidarabine. Vidarabine is an antiviral agent which is active against herpes simplex and varicella zoster viruses. Synonyms: Biotin-PEG8-Vidarabine|HY-145246|CS-0370379. Grade: >98%. Molecular formula: C36H60N8O13S. Mole weight: 844.97. | |
| Biotin-PEG9-CH2CH2COOH | Biotin-PEG9-CH2CH2COOH is a polyethylene glycol (PEG)-based PROTAC linker. Biotin-PEG9-CH2CH2COOH can be used in the synthesis of a series of PROTACs. Molecular formula: C31H57N3O13S. Mole weight: 711.86. | |
| Biotin-PEG9-NHS Ester | Biotin-PEG9-NHS Ester is a polyethylene glycol (PEG)-based PROTAC linker. Biotin-PEG9-NHS Ester can be used in the synthesis of a series of PROTACs. Molecular formula: C35H60N4O15S. Mole weight: 808.93. | |
| Biotin-PEG-AC, MW 1k-10k | Biotin-PEG-AC is a linear heterobifunctional PEG reagent with two different activated terminal groups. It is used in cell culture, pharmaceutical research, drug delivery and release, nanotechnology and new materials.Biotin terminal group can label specific molecules, structures or tissues. The other terminal group participates in kinds of active reactions. Biotin-PEG-AC can be used as argeted markers for small molecules or materials. Mole weight: Customizable. | |
| Biotin-PEG-azide, MW 1K-10K | Biotin-PEG-azide, MW 1,000 is a biotinylation reagent which has strong binding affinity to avidin or streptavidin. The azide moiety can react with terminal alkyne via copper click reaction or with cyclooctyne (BCN/DBCO) via copper-free click chemistry. Please contact us for GMP-grade inquiries. Synonyms: Biotin-PEG1-azide; 1204085-48-2; N-[2-(2-Azidoethoxy)ethyl]-biotinamide; BIOTIN-PEG-AZIDE; SCHEMBL23947625; DTXSID701118138; 5-[(3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4-d]imidazol-4-yl]-N-[2-(2-azidoethoxy)ethyl]pentanamide; AKOS040756543. Molecular formula: C14H24N6O3S. Mole weight: 356.45. | |
| Biotin-PEG-Biotin, MW 600-35k | Biotin-PEG-Biotin has two activated terminal groups. Biotin groups are often used in labeling. Homobifunctionalized PEG derivatives have wide applications in peptides, proteins, lipids, other small molecules and surface modifications. Drug PEGylation can alter its dispersity and solubility in aqueous solutions. PEG modification can create a spatial barrier around the drug, reduce the enzymatic hydrolysis of the drug, avoid the rapid elimination of kidney metabolism, and allow the drug to be recognized by cells of the immune system. Synonyms: Biotin-PEG-Biotin; SCHEMBL15216220; Biotin-PEG-Biotin, MW 1,000; Biotin-PEG-Biotin, MW 2,000; Biotin-PEG-Biotin, MW 3,400; Biotin-PEG-Biotin, MW 5,000; Biotin-PEG-Biotin, MW 10,000; HY-140656A. Molecular formula: C26H44N6O6S2. Mole weight: Customizable. | |
| Biotin-PEG-CH2CO2H, MW 1K-10K | Biotin-PEG-CH2CO2H, MW 1,000 is a carboxyl polyPEG used for biotinylation due to its strong binding with avidin/streptavidin. The carboxyl is reactive with amine in the presence of activating agent, such as HATU or EDC, to generate a covalent amide bond. Please contact us for GMP-grade inquiries. | |
| Biotin-PEG-COOH, MW 1k-10k | Biotin-PEG-AC is a linear heterobifunctional PEG reagent with two different activated terminal groups. It is used in cell culture, pharmaceutical research, drug delivery and release, nanotechnology and new materials.Biotin terminal group can label specific molecules, structures or tissues. The other terminal group participates in kinds of active reactions. Biotin-PEG-AC can be used as argeted markers for small molecules or materials. Mole weight: Customizable. | |
| Biotin-PEG-DMG | Biotin-PEG-DMG is a lipid used in the form of lipid nanoparticles. Synonyms: α-Biotin-ω-dimyristoyl glycerol poly(ethylene glycol). | |
| Biotin-PEG-MAL, MW 1k-10k | Biotin-PEG-MAL is a linear heterobifunctional PEGylation reagent with two different activated terminal groups. It is used in cell culture, pharmaceutical research, drug delivery and release, nanotechnology and new materials. Biotin terminal group can label specific molecules, structures or tissues. The other terminal group participates in kinds of active reactions. Biotin-PEG-MAL can be used as argeted markers for proteins or materials. Mole weight: Customizable. | |
| Biotin-PEG-NH2, MW 1k-10k | Biotin-PEG-NH2 is a linear heterobifunctional PEG reagent with two different activated terminal groups. It is used in cell culture, pharmaceutical research, drug delivery and release, nanotechnology and new materials. Biotin terminal group can label specific molecules, structures or tissues. The other terminal group participates in kinds of active reactions. Biotin-PEG-NH2 can be used as argeted markers for proteins or materials. Mole weight: Customizable. | |
| Biotin-PEG-NHS, MW 1k-4k | Biotin-PEG-NHS ester is a heterobifunctional PEG derivative containing a biotin group and an NHS ester group. Mole weight: Customizable. | |
| Biotin-PEG-OH, MW 1k-10k | Biotin-PEG-OH is a linear heterobifunctional PEGylation reagent with two different activated terminal groups. It is used in cell culture, pharmaceutical research, drug delivery and release, nanotechnology and new materials. Biotin terminal group can label specific molecules, structures or tissues. The other terminal group participates in kinds of active reactions. Biotin-PEG-OH can be used as argeted markers for proteins or materials. Mole weight: Customizable. | |
| Biotin-PEG-SCM, MW 1k-10k | Biotin-PEG-SCM with two different activated terminal groups, a biotin and a succinimidyl NHS ester. It is used in cell culture, pharmaceutical research, drug delivery and release, nanotechnology and new materials. Biotin terminal group can label specific molecules, structures or tissues. The other terminal group participates in kinds of active reactions. Biotin-PEG-SCM can be used as argeted markers for proteins or materials. Mole weight: Customizable. | |
| Biotin-PEG-SH, MW 1k-10k | Biotin-PEG-SH with two different activated terminal groups is used in cell culture, pharmaceutical research, drug delivery and release, nanotechnology and new materials. Biotin terminal group can label specific molecules, structures or tissues. The other terminal group participates in kinds of active reactions. Biotin-PEG-SH can be used as argeted markers for proteins or materials. Mole weight: Customizable. | |
| Biotin-PEG-Silane, MW 1k-10k | Biotin-PEG-Silane is a linear heterobifunctional PEG reagent with two different activated terminal groups. It is used in cell culture, pharmaceutical research, drug delivery and release, nanotechnology and new materials. Biotin terminal group can label specific molecules, structures or tissues. Silane can modify the surface of metallic materials. Biotin-PEG-Silane can be used as argeted markers for proteins or materials. Mole weight: Customizable. | |
| Biotin-PEG-Succinimidyl Carbonate, MW 5K | Biotin-PEG-Succinimidyl Carbonate, MW 5,000 is a PEG polymer active ester which is reactive with amine via formation of amide bond. The biotin has strong binding affinity with streptavadin and avadin. Please contact us for GMP-grade inquiries. | |
| Biotin-PEG-Succinimidyl glutaramide, MW 3.5k | Biotin-PEG-succinimidyl glutaramide is a heterobifunctional PEG derivative containing a biotin group and a succinimidyl glutaramide group. | |
| Biotin-PEG-Succinimidyl Valerate, MW 3.4K-5K | Biotin-PEG-Succinimidyl Valerate, MW 3,400 is a biotin PEGylation reagent with an NHS ester which is reactive specifically and efficiently with lysine and N-terminal amino groups at pH 7-9 to form a stable amide bond. Please contact us for GMP-grade inquiries. | |
| Biotin pentafluorophenyl ester | Biotin pentafluorophenyl ester is used to prepare melampomagnolide B as an antileukemic sesquiterpene. Synonyms: Biotin-PFP ester; (+)-Biotin-PFP-ester; Perfluorophenyl 5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoate; Biotin-PFP; Biotin-OPFP; Pentafluorophenyl 5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoate; AK103675; EZ-Link PFP-Biotin; SCHEMBL140972; D-Biotin pentafluorophenyl ester; CTK8C0381; DTXSID80455998; (+)-Biotin pentafluorophenyl ester; (3aS,3abeta,6abeta)-2-Oxohexahydro-1H-thieno[3,4-d]imidazole-4alpha-pentanoic acid; pentafluorophenyl ester; PFP-Biotin. Grade: 98 % (HPLC). CAS No. 120550-35-8. Molecular formula: C16H15F5N2O3S. Mole weight: 410.36. | |
| Biotin-Phosphatidic Acid | Biotin-Phosphatidic Acid is a biotinylated conjugate of Phosphatidic Acid. Phosphatidic acid (PA) is a major component of cell membranes with important biophysical, metabolic, and signaling roles. PA has been implicated in many aspects of animal cell biochemistry and physiology, including cell proliferation and differentiation, cell transformation, tumor progression and survival signaling. Synonyms: Biotin-PA. Molecular formula: C41H75N4O11PS. Mole weight: 863.10. | |
| Biotin-Phosphatidylcholine | Biotin-Phosphatidylcholine is a functionalized phosphatidylcholine with biotin conjugated to the sn1 acyl chain. Phosphatidylcholine (PC) is generally the most abundant lipid in animal cell membranes providing structural framework. PC is also the primary substrate of Phospholipase D enzymes which produce the signaling lipids - phosphatidic acid and lysophosphatidic acid. Synonyms: Biotin-PC. Grade: >95%. Molecular formula: C46H86N5O11PS. Mole weight: 948.20. | |
| Biotin-Phosphatidylethanol (12:0/18:1) | Biotin-PEth is the first PEth analog used to build biological assays testing for serum and in vitro PEth levels. PEth is formed primarily in the liver by transphosphatidylation of phosphatidylcholine (PC) by phospholipase D. Most PEth (about 75%) is incorporated into erythrocyte membranes, and is the longest-lived circulating ethanol metabolite yet identified. Synonyms: Biotin-PEth (12:0/18:1). Molecular formula: C51H93N4O11PS. Mole weight: 1001.36. | |
| Biotin-Phosphatidylethanol (6:0/16:0) | Biotin-PEth is the first PEth analog used to build biological assays testing for serum and in vitro PEth levels. PEth is formed primarily in the liver by transphosphatidylation of phosphatidylcholine (PC) by phospholipase D. Most PEth (about 75%) is incorporated into erythrocyte membranes, and is the longest-lived circulating ethanol metabolite yet identified. Synonyms: Biotin-PEth (6:0/16:0). Molecular formula: C43H78N4O11PS. Mole weight: 890.15. | |
| Biotin-Phosphatidylethanolamine | Biotin-Phosphatidylethanolamine is a biotinylated conjugate of phosphatidylethanolamine. Phosphatidylethanolamine (PE) is formed primarily in the reaction of CDP-ethanolamine and diacylglycerol. PE is one of the major components of cell membranes in bacteria and in nervous system. Synonyms: Biotin-PE. Molecular formula: C43H80N5O11PS. Mole weight: 906.17. | |
| Biotin-Phosphatidylglycerol | Biotin-Phosphatidylglycerol is a biotinylated conjugate of phosphatidylglycerol (PG). Phosphatidylglycerol (PG) is a minor component (1-2%) of most of cell membranes. It can be found at higher concentrations (up to 11% of the total lipid content) in lung surfactant. PG is also used by cells as an intermediate in cardiolipin synthesis. Bacterial membranes contain up to 20% of PG. Synonyms: Biotin-PG. Molecular formula: C44H81N4O13PS. Mole weight: 937.18. | |
| Biotin Phosphatidylinositol | Biotin Phosphatidylinositol is a water-soluble analog of Phosphatidylinositol labelled with biotin at the sn-1 position. Phosphatidylinositol (PI or PtdIns) is biosynthesized from CDP-diacylglycerol and inositol by phosphatidylinositol synthase. PI is the building block for phosphoinositide polyphosphates through phosphorylation by PI-kinases and is a substrate for PI-PLC yielding diacylgelycerol. Synonyms: Biotin PI. Grade: >95%. Molecular formula: C37H64N4NaO16PS. Mole weight: 906.95. | |
| Biotin Phosphatidylinositol 3,4-bisphosphate | Biotin Phosphatidylinositol 3,4-bisphosphate is a water-soluble analog of PI(3,4)P2 labelled with biotin at the sn-1 position. PI(3,4)P2 is produced in stimulated cells by the action of phosphatidylinositol 3-kinases (PI3Ks) and/or lipid phosphatases (SHIP, TPTE, etc.). PI(3,4)P2 binds the pleckstrin homology (PH)-domain of AKT/PKB leading to cell survival and it also has an important role in podosome formation near focal adhesions. Synonyms: Biotin PI(3,4)P2. Grade: >95%. Molecular formula: C37H62N4Na5O22P3S. Mole weight: 1153.84. | |
| Biotin Phosphatidylinositol 3,5-bisphosphate | Biotin Phosphatidylinositol 3,5-bisphosphate is a water-soluble analog of PI(3,5)P2 labelled with biotin at the sn-1 position. PI(3,5)P2 is in very low abundance and is required for retrograde membrane trafficking from lysosomal and late endosomal compartments to the Golgi and is involved in autophagy. PI(3,5)P2 levels are controlled by the 5-kinase PIKfyve and the 5-phosphatase Fig4/Sac3 and disregulation is linked to several human neuropathies (eg Chacot-Marie-Tooth disease). Synonyms: Biotin PI(3,5)P2. Grade: >95%. Molecular formula: C37H62N4Na5O22P3S. Mole weight: 1154.84. | |
| Biotin Phosphatidylinositol 3-phosphate | Biotin Phosphatidylinositol 3-phosphate is a water-soluble analog of PI(3)P labelled with biotin at the sn-1 position. PI(3)P is enriched in early endosomes having roles in endosome fusion and receptor sorting and internalization in multivesicular bodies. PI(3)P has also been found at the plasma membrane and is involved in the translocation of the glucose transport protein GLUT4. Synonyms: Biotin PI(3)P. Grade: >95%. Molecular formula: C37H63N4Na3O19P2S. Mole weight: 1030.90. | |
| Biotin Phosphatidylinositol 4,5-bisphosphate | Biotin Phosphatidylinositol 4,5-bisphosphate is a water-soluble analog of PI(4,5)P2 labelled with biotin at the sn-1 position. PI(4,5)P2 has been shown to play a central role in a variety of cellular functions. Amongst its many functions, PIP2 is a substrate for Phospholipase C-coupled G-protein pathways involved in intracellular calcium release in a number of tissues. It is also a substrate for class I phosphoinositide 3-kinase (PI3-K) forming PI(3,4,5)P3. Synonyms: Biotin PI(4,5)P2. Grade: >95%. Molecular formula: C37H62N4Na5O22P3S. Mole weight: 1154.84. | |
| Biotin Phosphatidylinositol 4-phosphate | Biotin Phosphatidylinositol 4-phosphate is a water-soluble analog of PI(4)P labelled with biotin at the sn-1 position. PI(4)P is the biosynthetic precursor to PI(4,5)P2 and has an important role in regulating sphingomyelin and glycosphingolipid metabolism and membrane trafficking at the exit of the Golgi complex. Synonyms: Biotin PI(4)P. Grade: >95%. Molecular formula: C37H64N4NaO16PS. Mole weight: 906.95. | |
| Biotin Phosphatidylinositol 5-phosphate | Biotin Phosphatidylinositol 5-phosphate is a water-soluble analog of PI(5)P labelled with biotin at the sn-1 position. Phosphatidylinositol 5-phosphate is a rare lipid found in the nucleus that can bind the PHD finger of the nuclear adapter protein ING2. PI(5)P is phosphorylated to PI(4,5)P2 by Type II PIP kinases. Synonyms: Biotin PI(5)P. Grade: >95%. Molecular formula: C37H63N4Na3O19P2S. Mole weight: 1030.89. | |
| Biotin-Phosphatidylserine | Biotin-Phosphatidylserine is a biotinylated conjugate of phosphatidylserine (PS), a negatively charged phospholipid located in the inner leaflet of the cell membrane. During apoptosis PS is no longer restricted to the inner leaflet of the plasma membrane and migrates to the outer leaflet. Similarly, during platelet activation, PS is translocated to the outer side where it facilitates assembly of the prothrombinase complex. Synonyms: Biotin-PS. Molecular formula: C44H80N5O13PS. Mole weight: 950.18. | |
| Biotin Phosphoramidite | Biotin Phosphoramidite is a reagent used to incorporate biotin into oligonucleotides during solid-phase synthesis. The biotin moiety, known for its strong affinity to streptavidin, allows for easy detection, purification, and immobilization of the modified oligonucleotides. This makes it a valuable tool in molecular biology for labeling, assays, and targeted delivery applications. Biotinylated oligonucleotides are commonly used in techniques such as ELISA, Western blotting, and nucleic acid hybridization, providing a versatile and efficient way to enhance the functionality of DNA and RNA sequences. Synonyms: 1-Dimethoxytrityloxy-2-(N-biotinyl-4-aminobutyl)-propyl-3-O-(2-cyanoethyl)-(N,N-diisopropyl)-phosphoramidite; Phosphoramidous acid, N,N-bis(1-methylethyl)-, 2-[2-[2-[[5-[(3aS,4S,6aR)-1-[bis(4-methoxyphenyl)phenylmethyl]hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]amino]ethoxy]ethoxy]ethyl 2-cyanoethyl ester; 2-[2-[2-[[5-[(3aS,4S,6aR)-1-[Bis(4-methoxyphenyl)phenylmethyl]hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]amino]ethoxy]ethoxy]ethyl 2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite; Biotin-amidite; DMTr-biotin-PEG3-(2-cyanoethyl) diisopropylphosphoramidite. Grade: ≥96%. CAS No. 1217500-22-5. Molecular formula: C46H64N5O8PS. Mole weight: 878.07. | |
| BIOTIN PHOSPHORAMIDITE FOR ABI | BIOTIN PHOSPHORAMIDITE FOR ABI. CAS No. 196408-65-8. Molecular formula: C49H69N6O8PS. Mole weight: 933.1. | |
| Biotin phosphoramidite (hydroxyprolinol) | Non-nucleosidic modifier reagent for the synthesis of biotinylated oligos based on a hydroxyprolinol core. This phosphoramidite contains a dimethoxytrityl protective group for the purification of the resulting oligos on C18 cartridges, and reverse phase HPLC. This modifier reagent can be used to introduce biotin onto 5'-position, 3'-position (using universal CPG), and internal oligo sites. This amidite does not require special condensation and deprotection conditions. Grade: NMR 1H, 31P, HPLC-MS (95%), functional testing in oligo synthesis. Molecular formula: C51H71N6O8PS. Mole weight: 959.18. | |
| Biotin PI(3,4,5)P3 | Biotin PI(3,4,5)P3 is a water-soluble analog of PI(3,4,5)P2 (PIP3) labelled with biotin at the sn-1 position. Phosphatidylinositol 3,4,5-trisphosphate (PIP3), formed from PI(4,5)P2 through phosphorylation by PI 3-kinase, activates numerous signaling pathways resulting in cell proliferation, growth, survival, glucose transport and protein synthesis. PIP3 is hydrolyzed by the phosphatases PTEN to PI(4,5)P2 and SHIP to PI(3,4)P2. Synonyms: Biotin Phosphatidylinositol 3,4,5-trisphosphate. Grade: >95%. Molecular formula: C37H61N4Na7O25P4S. Mole weight: 1278.78. | |
| BIOTIN-PROPRANOLOL ANALOG | BIOTIN-PROPRANOLOL ANALOG. CAS No. 69079-54-5. Molecular formula: C25H34N4O4S. Mole weight: 486.6. | |
| Biotin S1P | Sphingosine 1-phosphate biotin is a S1P analog with natural erythro stereochemistry labeled at the terminus of the alkyl chain with biotin. Biotin S1P is produced by the phosphorylation of biotinyl sphingosine by recombinant human sphingosine kinase 1 and 2 (hSK1 and hSK2). Synonyms: omega-biotinyl D-erythro-sphingosine-1-phosphate; (2S,3R,4E)-2-Azaniumyl-3-hydroxy-18-({5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoyl}amino)octadec-4-en-1-yl hydrogen phosphate. Grade: >99%. CAS No. 799812-63-8. Molecular formula: C28H53N4O7PS. Mole weight: 620.78. | |
| Biotin-sar-oh | Biotin-sar-oh is a cleavable linker widely used in conjugated drug development. It has ultra-modern applicability as a targeted therapeutic adjunct that selectively binds to malignant cellular entities and strongly inhibits their proliferative activity. Synonyms: Biotin-sar-oh; (+)-Biotin-sarcosine; 2-[5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoyl-methylamino]acetic acid; n-biotinylsarcosine. Grade: ≥ 95%. CAS No. 154024-76-7. Molecular formula: C13H21N3O4S. Mole weight: 315.39. | |
| (+)-Biotin-SLC | (+)-Biotin-SLC is a PROTAC linker, which is composed of alkyl chains. (+)-Biotin-SLC can be used to synthesize a range of PROTACs. CAS No. 1864003-57-5. Molecular formula: C21H37N3O4S. Mole weight: 427.60. | |
| Biotin Sphingomyelin | Biotin Sphingomyelin is a biotin conjugate of Sphingomyelin. Biotin Sphingomyelin can be bound to streptavidin coated surfaces for protein binding experiments and assay development. Sphingomyelin is a lipid constituent in the exoplasmic face of cell membranes. Sphingomyelin is hydrolyzed by Sphingomyelinases to the proapoptotic messenger Ceramide and phosphorylcholine. Molecular formula: C39H74N5O8PS. Mole weight: 804.08. | |
| Biotin-ß-Alanine-13C3,15N-C2-Azide | Click Chemistry Heavy Isotopes. Molecular formula: C12[13C]3H25N6[15N]O3S. Mole weight: 387.47. | |
| Biotin-ß-Alanine-Alkyne | Biotin-ß-Alanine-Alkyne is a reagent used in conjunction with Biotin-beta-Alanine-13C3,15N-Alkyne in click chemistry. Synonyms: Biotin Propargyl amide. Molecular formula: C16H24N4O3S. Mole weight: 352.45. | |
| Biotin-ß-Alanine-C2-Azide | Biotin-ß-Alanine-C2-Azide is a reagent used in click chemistry. Molecular formula: C15H25N7O3S. Mole weight: 383.47. | |
| Biotin-ß-Alanine SE | Biotin-ß-Alanine SE. Synonyms: Biotin-ß-Alanine Succinimidyl Ester. Molecular formula: C17H24N4O6S. Mole weight: 412.46. | |
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