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Amphiphatic peptide CT1
Amphiphatic peptide CT1 is an α-helical short antimicrobial peptide produced by venom scorpion Vaejovis mexicanus smithi. It has broad-spectrum antibacterial activity. Synonyms: VmCT1; Phe-Leu-Gly-Ala-Leu-Trp-Asn-Val-Ala-Lys-Ser-Val-Phe-NH2; Non-disulfide-bridged peptide 5.13; NDBP-5.13. Grades: >95%. Molecular formula: C72H107N17O15. Mole weight: 1450.75.
Amphiphatic peptide CT2
Amphiphatic peptide CT2 is an α-helical short antimicrobial peptide produced by venom scorpion Vaejovis mexicanus smithi. It has broad-spectrum antibacterial activity. Synonyms: VmCT2; Phe-Leu-Ser-Thr-Leu-Trp-Asn-Ala-Ala-Lys-Ser-Ile-Phe-NH2; Non-disulfide-bridged peptide 5.14; NDBP-5.14. Grades: ≥97%. Molecular formula: C73H109N17O17. Mole weight: 1496.78.
Amphistin
It is produced by the strain of Actinornycete KP-3052. It has weak antibacterial activity. Inhibition of melanoma cell B16 production of melanin without affecting the growth of the cell, IC50 is 55 μmol/L. Synonyms: amphistin. Molecular formula: C13H21N5O6. Mole weight: 343.33.
Amphomycin
It is produced by the strain of Streptomyces canus. It is primarily resistant to gram-positive bacteria. Synonyms: Amfomycine; Amfomycinum; Anfomicina; Glumamycin; Amfomycin; A1437E. Grades: >95% by HPLC. CAS No. 1402-82-0. Molecular formula: C58H91N13O20. Mole weight: 1290.41.
Amphotericin A
It is produced by the strain of Streptomyces nodosus. The antifungal spectrum is wide and the activity is strong. Synonyms: (4E,6E,8E,10E,14E,16E)-3-(4-amino-3,5-dihydroxy-6-methyloxan-2-yl)oxy-19,25,27,30,31,33,35,37-octahydroxy-18,20,21-trimethyl-23-oxo-22,39-dioxabicyclo[33.3.1]nonatriaconta-4,6,8,10,14,16-hexaene-38-carboxylic acid. Grades: ≥ 95%. CAS No. 1405-32-9. Molecular formula: C47H75NO17. Mole weight: 926.09.
Amphotericin B
It is produced by the strain of Streptomyces nodosus. It is an important antifungal drug, especially for deep fungal infection. Liposomes were prepared to reduce toxic and side effects. Synonyms: amphotericin b; Amfotericina B; Amphotericinum B; AMPH-B; Fungizone; Liposomal Amphotericin B; Amphotericine B; Ambisome; Amphozone; Fungilin; NSC 527017; NSC527017; NSC-527017. Grades: >98%. CAS No. 1397-89-3. Molecular formula: C47H73NO17. Mole weight: 924.08.
Ampicillin
Ampicillin is a broad-spectrum antibiotic used to prevent and treat a variety of bacterial infections. It is used to treat infectious diseases caused by sensitive chicken bacteria, such as Escherichia coli, Salmonella, Pasteurella, Staphylococcus and Streptococcus infections. Synonyms: Pentrexyl; Principen; D-(-)-α-Aminobenzylpenicillin; Sultamicillin EP Impurity C; Aminobenzylpenicillin; Ampicillin acid; Amcill; Polycillin; Principen; Omnipen; Ampicilline; Penbritin. Grades: >98%. CAS No. 69-53-4. Molecular formula: C16H19N3O4S. Mole weight: 349.40.
Ampicillin Impurity B
Cas No. 19379-33-0.
Ampicillin Impurity D
Cas No. 1642629-93-3.
Ampicillin impurity E
Cas No. 1207726-28-0.
Ampicillin impurity F
Cas No. 124774-48-7.
Ampicillin impurity G
Cas No. 31485-02-6.
Ampicillin impurity H
Cas No. 73200-73-4.
Ampicillin impurity I
Cas No. 10001-82-8.
Ampicillin impurity J
Cas No. 6489-58-3.
Ampicillin impurity K
Cas No. 40610-41-1.
Ampicillin Sodium Mixture With Sulbactam Sodium
Ampicillin Sodium Mixture with Sulbactam Sodium is a β-lactamase inhibitor used to enhance the effectiveness of β-lactam antibiotics. Synonyms: Unacyne; Unacid; Unasyn-S; Yucion-S. CAS No. 117060-71-6. Molecular formula: C25H29N3Na2O9S2. Mole weight: 625.62.
AMP - lyophilized
AMP - lyophilized is also known as adenosine monophosphate. With its role in multiple biochemical pathways, extensive research has been conducted to explore its potential in fortifying immune responses is augmenting mitochondrial functionality is as well as ameliorating neurological afflictions. Furthermore, this lyophilized iteration offering a convenient means of storage and reconstitution, facilitating further investigation and potential preclinical utilization. Synonyms: Adenosine-5'-monophosphate, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C10H14N5O7P (free acid). Mole weight: 347.22 (free acid).
AMPPD disodium salt
AMPPD is a chemiluminescent enzyme substrate applied in clinical diagnostics. Synonyms: Lumigen PPD; 3-(4-Methoxyspiro[1,2-dioxetane-3,2'-tricyclo[3.3.1.1(3,7)]decan]-4-yl)phenol dihydrogen phosphate disodium salt. CAS No. 124951-96-8. Molecular formula: C18H21Na2O7P. Mole weight: 426.3.
AMP PNP
AMP PNP is an analogue of AMP and has been found to be a Kir6 (KATP) channel blocker. Synonyms: Adenosine-5'-[(β,γ)-imido]triphosphate tetralithium salt. Grades: ≥90% by HPLC. CAS No. 72957-42-7. Molecular formula: C10H13Li4N6O12P3. Mole weight: 529.93.
Amprenavir
Amprenavir promotes the specific interactions between the nuclear receptor pregnane X receptor (PXR) and the coactivators SRC-1 and PBP. Uses: Amprenavir is indicated in combination with other antiretroviral agents in the treatment of hiv-1 infection. Synonyms: VX-478; VX 478; VX478; Amprenavir; Agenerase; Prozei. Grades: >98%. CAS No. 161814-49-9. Molecular formula: C25H35N3O6S. Mole weight: 505.63.
Ampullosporin A is produced by the strain of Sepedonium ampullosporum HKI-0053. Its antibacterial spectrum is narrow. The anti-staphylococcus aureus GS511, Bacillus subtilis, Pseudomonas aeruginosa K599/WT, Escherichia coli SG458, Ocher sporococcus SBUG 549 and Deep red yeast and other bacteria and fungi had only moderate intensity activity, and had no effect on other yeast and candida albicans. It can cause Phoma destructiva to form pigment. Its content is greater than 1mg/kg, which can cause hypothermia and reduce automatic exercise in rats. Synonyms: N-Acetyl-L-tryptophyl-L-alanyl-2-methylalanyl-2-methylalanyl-L-leucyl-2-methylalanyl-L-glutaminyl-2-methylalanyl-2-methylalanyl-2-methylalanyl-L-glutaminyl-L-leucyl-2-methylalanyl-N1-[(1S)-1-(hydroxymethyl)-3-methylbutyl]-L-glutamamide. CAS No. 197960-94-4. Molecular formula: C77H127N19O19. Mole weight: 1622.94.
Amrinone
Amrinone is a selective cAMP phosphodiesterase (PDE-3) inhibitor with positive inotropic and vasodilatory activity. It is a simple, non-glycoside cardiotonic agent. It provides protection against ischemia-reperfusion injury in kidney, liver, and heart. It has the ability to stimulate calcium ion influx into the cardiac cell. It is used in the treatment of congestive heart failure. It increases cardiac contractility as a vasodilator. It acts by inhibiting the breakdown of both cAMP and cGMP by the phosphodiesterase (PDE3) enzyme. It is a drug that may improve the prognosis in patients with congestive heart failure. It has been shown to increase the contractions initiated in the heart by high gain calcium induced calcium release (CICR). It was developed by Sanofi and has been listed. Uses: Amrinone is a simple, non-glycoside cardiotonic agent. it provides protection against ischemia-reperfusion injury in kidney, liver, and heart. it is used in the treatment of congestive heart failure. it increases cardiac contractility as a vasodilator. Synonyms: Inamrinone; Wincoram; Inocor; Cordemcura; Win-40680; Win40680; 3-Amino-5-pyridin-4-yl-1H-pyridin-2-one. Grades: 98%. CAS No. 60719-84-8. Molecular formula: C10H9N3O. Mole weight: 187.20.
Amrubicin
Cas No. 110267-81-7.
Amrubicin hydrochloride
Amrubicin hydrochloride is a topoisomerase II inhibitor used in the treatment of lung cancer. Uses: Antineoplastic agents. Synonyms: Amrubicin HCl; SM-5887; Calsed; 5,12-Naphthacenedione, 7,8,9,10-tetrahydro-9-acetyl-9-amino-7-((2-deoxy-beta-D-erythro-pentopyranosyl)oxy)-6,11-dihydroxy-, hydrochloride, (7S-cis)-; 5,12-Naphthacenedione, 9-acetyl-7-((2-deoxy-beta-D-erythro-pentopyranosyl)oxy)-7,8,9,10-tetrahydro-6,11-dihydroxy-, hydrochloride, (7S,9S)-. Grades: >98%. CAS No. 110311-30-3. Molecular formula: C25H26ClNO9. Mole weight: 519.93.
Amrubicinol (Mixture of Diastereomers)
A metabolite of Amrubicin, which is active and possesses a cytotoxicity 10 to 100 times that of the parent drug. Uses: A metabolite of amrubicin, which is active and possesses a cytotoxicity 10 to 100 times that of the parent drug. Synonyms: (7S,9S)-9-Amino-7-[(2-deoxy-β-D-erythro-pentopyranosyl)oxy]-7,8,9,10-tetrahydro-6,11-dihydroxy-9-(1-hydroxyethyl)-5,12-naphthacenedione; 13-Hydroxy SM 5887. CAS No. 186353-53-7. Molecular formula: C25H27NO9. Mole weight: 485.48.
Amsacrine
Amsacrine is an antineoplastic agent which can intercalate into the DNA of tumor cells. It also expresses topoisomerase inhibitor activity, specifically inhibiting topoisomerase II. Synonyms: AMSA; m-AMSA; CI 880, CI880, CI-880; SN-11841; SN 11841; SN11841; acridinyl anisidide. Grades: >98%. CAS No. 51264-14-3. Molecular formula: C21H19N3O3S. Mole weight: 393.46.
Amsacrine hydrochloride
Amsacrine hydrochloride is an antineoplastic agent which can intercalate into the DNA of tumor cells. It also expresses topoisomerase inhibitor activity, specifically inhibiting topoisomerase II. Uses: Antineoplastic agents. Synonyms: AMSA hydrochloride; m-AMSA hydrochloride; CI-880 hydrochloride; SN-11841 hydrochloride; CI 880 hydrochloride; SN 11841 hydrochloride; CI880 hydrochloride; SN11841 hydrochloride; acridinyl anisidide hydrochloride. Grades: >98%. CAS No. 54301-15-4. Molecular formula: C21H20ClN3O3S. Mole weight: 429.92.
AMT hydrochloride
The hydrochloride salt form of AMT, which has been found to be a reversible inhibitor of iNOS and could probably be useful in treatment of inflammatory and autoimmune disorders. Synonyms: 2-Amino-5,6-dihydro-6-methyl-4H-1,3-thiazine hydrochloride. Grades: ≥95% by HPLC. CAS No. 21463-31-0. Molecular formula: C5H10N2S.HCl. Mole weight: 166.67.
AM-TS23
AM-TS23 has been found to be a DNA polymerase λ and β inhibitor and could be effective in studies of colorectal cancer. Synonyms: AM-TS23; AM TS23; AMTS23; (5Z)-5-[[(4-[(2-Methylphenyl)thio]-3-nitrophenyl]methylene]-2-thioxo-4-thiazolidinone. Grades: ≥98% by HPLC. CAS No. 1489285-17-7. Molecular formula: C17H12N2O3S3. Mole weight: 388.48.
Amudol
It is produced by the strain of Penicillum martensii. It has a weak antibacterial activity against S. aureus, E. coli, salmonella, etc. Synonyms: 2,5-Dihydroxy-4-chlorbenzylalkohol. CAS No. 31302-46-2. Molecular formula: C7H7ClO3. Mole weight: 174.58.
Amuvatinib
Amuvatinib, also known as MP-470, is an orally bioavailable synthetic carbothioamide with potential antineoplastic activity. MP470 inhibits activities of other receptor tyrosine kinases. This agent also suppresses the induction of DNA repair protein Rad51, thereby potentiating the activities of DNA damage-inducing agents. Synonyms: HPK 56; HPK-56; HPK56; MP-470; MP470; MP 470. Grades: 0.98. CAS No. 850879-09-3. Molecular formula: C23H21N5O3S. Mole weight: 447.513.
AMY-101
C3 Complement Inhibitor AMY-101 is a compstatin-based inhibitor of human complement component C3. AMY-101 (Cp40) exhibits a favorable anti-inflammatory activity in models with COVID-19 severe pneumonia with systemic hyper inflammation. Synonyms: Compstatin 40; Cp40. Grades: ≥98%. CAS No. 1427001-89-5. Molecular formula: C83H117N23O18S2. Mole weight: 1789.11.
Amycin A
It is produced by the strain of Streptomyces sp. DSM 3816. The activity of Amycin A is weaker than that of Amycin B. CAS No. 116296-63-0. Molecular formula: C62H105N3O21. Mole weight: 1228.50.
Amycin B
It is produced by the strain of Streptomyces sp. DSM 3816. It has the activity of anti-ringworm, microspora, candida, aspergillus and other fungi and gram-positive bacteria such as staphylococcus and streptococcus. Synonyms: Scopafungin, 23-O-de(carboxyacetyl)-8,47-didemethyl-14,49-dimethyl-. CAS No. 129313-99-1. Molecular formula: C56H101N3O15. Mole weight: 1056.41.
Amycolatopsin A
Amycolatopsin A is a macrolide polyketide found in Amycolatopsis that has antimycobacterial and anticancer activities. It is active against M. bovis and M. tuberculosis (IC50s = 0.4 and 4.4 μM, respectively) but not B. subtilis, S. aureus, E. coli, or P. aeruginosa (IC50s = >30 μM for all). Amycolatopsin A is also cytotoxic to SW620 colorectal and NCI H460 lung cancer cells (IC50s = 0.08 and 1.2 μM, respectively). Grades: ≥95%. CAS No. 2209112-96-7. Molecular formula: C60H98O23. Mole weight: 1187.40.
Amycolatopsin B
Amycolatopsin B is a bacterial metabolite produced by Amycolatopsis that has anticancer activity. It is cytotoxic to NCI H460 lung and SW620 colon cancer cells (IC50s = 0.28 and 0.14 μM, respectively). Grades: >95%. CAS No. 2209112-97-8. Molecular formula: C60H98O22. Mole weight: 1171.40.
Amycolatopsin C
Amycolatopsin C is a polyketide macrolide that has been found in Amycolatopsis and has antimycobacterial and anticancer activities. It is active against M. bovis and M. tuberculosis (IC50s = 2.7 and 5.7 μM, respectively). Amycolatopsin C is also cytotoxic to SW620 colorectal and NCI H460 lung cancer cells (IC50s = 10 and 5.9 μM, respectively). Grades: ≥95%. Molecular formula: C47H76O17. Mole weight: 913.09.
Amygdalin
Amygdalin is a glycoside initially isolated from the seeds of the tree Prunus dulcis, also known as bitter almonds. The active ingredient of amygdalin is a naturally occurring cyanide, which is a human metabolite and can only play a role in cancer cells. Uses: Antitumor/antifibrotic. Synonyms: Benzeneacetonitrile, α-[(6-O-β-D-glucopyranosyl-β-D-glucopyranosyl)oxy]-, (αR)-; (α R) -α -[ (6-O-β -D-Glucopyranosyl-β -D-glucopyranosyl) oxy]benzeneacetonitrile; Benzeneacetonitrile, α-[(6-O-β-D-glucopyranosyl-β-D-glucopyranosyl)oxy]-, (R)-; (-)-Amygdalin; (R)-Amygdalin; D-Amygdalin; Amygdaloside; Amygdaloside (disaccharide); Mandelonitrile-β-gentiobioside; NSC 15780. Grades: >98%. CAS No. 29883-15-6. Molecular formula: C20H27NO11. Mole weight: 457.43.
Amyl 2-acetamido-2-deoxy-b-D-glucopyranoside
Amyl 2-acetamido-2-deoxy-b-D-glucopyranoside is a versatile biomedical compound, finding applications in the research of an array of ailments. Identified as N-acetylmuramic acid, this compound showcases notable antibacterial attributes, rendering it invaluable in the enzymatic assessment of bacterial muramidases. Crucially, it assumes an indispensable role in peptidoglycan research and development, a pivotal constituent of bacterial cell walls. Synonyms: Amyl 2-acetamido-2-deoxy-b-D-glucopyranoside; N-((2R,3R,4R,5S,6R)-4,5-Dihydroxy-6-(hydroxymethyl)-2-(pentyloxy)tetrahydro-2H-pyran-3-yl)acetamide; Amyl-2-acetamido-2-deoxy-b-D-glucopyranoside; AKOS002687849; N-[(2R,3R,4R,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-2-pentoxyoxan-3-yl]acetamide; E86926; b-D-Glucopyranoside,pentyl2-(acetylamino)-2-deoxy-; W-204110; AMYL 2-ACETAMIDO-2-DEOXY-BETA-D-GLUCOPYRANOSIDE; N-[(2R,3R,4R,5S,6R)-4,5-DIHYDROXY-6-(HYDROXYMETHYL)-2-(PENTYLOXY)OXAN-3-YL]ACETAMIDE. CAS No. 94483-64-4. Molecular formula: C13H25NO6. Mole weight: 291.34.
Amyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-b-D-glucopyranoside is an extensively employed compound in the realm of biomedicine, manifesting as an invaluable asset for the scrutiny of glycosylation mechanisms and the pioneering of groundbreaking pharmaceuticals. Synonyms: beta-D-Glucopyranoside, pentyl 2-(acetylamino)-2-deoxy-, 3,4,6-triacetate; Amyl-2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-b-D-glucopyranoside;b-D-Glucopyranoside,pentyl2-(acetylamino)-2-deoxy-,3,4,6-triacetate; [(2R,3S,4R,5R,6R)-5-acetamido-3,4-diacetyloxy-6-pentoxyoxan-2-yl]methyl acetate; [(2R,3S,4R,5R,6R)-3,4-BIS(ACETYLOXY)-5-ACETAMIDO-6-(PENTYLOXY)OXAN-2-YL]METHYL ACETATE. CAS No. 146288-30-4. Molecular formula: C19H31NO9. Mole weight: 417.45.
It is a polypeptide sequence containing 37 amino acids. Synonyms: Diabetes-associated peptide; IAPP; IAPP protein; Insulinoma amyloid peptide; Insulinoma amyloid polypeptide; Islet amyloid polypeptide; Protein IAPP; Proteins, IAPP. Grades: 95%. CAS No. 106602-62-4.
Amylin (8-37), rat
Amylin (8-37), rat is a truncated natural Amylin analogue that selectively inhibits insulin-related glucose uptake and glycogen deposition in muscle tissue. Synonyms: Amylin (8-37) (mouse, rat); H-Ala-Thr-Gln-Arg-Leu-Ala-Asn-Phe-Leu-Val-Arg-Ser-Ser-Asn-Asn-Leu-Gly-Pro-Val-Leu-Pro-Pro-Thr-Asn-Val-Gly-Ser-Asn-Thr-Tyr-NH2; L-alanyl-L-threonyl-L-glutaminyl-L-arginyl-L-leucyl-L-alanyl-L-asparagyl-L-phenylalanyl-L-leucyl-L-valyl-L-arginyl-L-seryl-L-seryl-L-asparagyl-L-asparagyl-L-leucyl-glycyl-L-prolyl-L-valyl-L-leucyl-L-prolyl-L-prolyl-L-threonyl-L-asparagyl-L-valyl-glycyl-L-seryl-L-asparagyl-L-threonyl-L-tyrosinamide. Grades: ≥95%. CAS No. 138398-61-5. Molecular formula: C140H227N43O43. Mole weight: 3200.61.
Amylin (human) (amidated) trifluoroacetate salt
Amylin is a pancreatic β-cell hormone that produces effects in several different organ systems. Amylin is a 37-amino-acid peptide that activates its specific receptors, which are multisubunit G protein and resulting in multiple receptor subtypes. Amylin's major role is as a glucoregulatory hormone, and it is an important regulator of energy metabolism in health and disease. Amidated amylin increases the rate of glycogen synthesis induced by insulin in isolated rat soleus muscle when used at a concentration of 1 nM, while linear non-amidated amylin has no effect. Synonyms: IAPP (human) (amidated); Islet Amyloid Polypeptide (human) (amidated). Grades: ≥95%. Molecular formula: C165H261N51O55S2·xCF3COOH. Mole weight: 3903.28.
Amylin (human) trifluoroacetate salt
Amylin is a pancreatic β-cell hormone that produces effects in several different organ systems. Amylin is a 37-amino-acid peptide that activates its specific receptors, which are multisubunit G protein and resulting in multiple receptor subtypes. Amylin's major role is as a glucoregulatory hormone, and it is an important regulator of energy metabolism in health and disease. Amidated amylin increases the rate of glycogen synthesis induced by insulin in isolated rat soleus muscle when used at a concentration of 1 nM, while linear non-amidated amylin has no effect. Synonyms: IAPP (human); Islet Amyloid Polypeptide (human). Grades: ≥95%. Molecular formula: C165H260N50O56S2·xCF3COOH. Mole weight: 3904.27.
Amylin (IAPP), feline
Amylin (IAPP), feline is a regulatory polypeptide consisting of 37 amino acids that inhibits the secretion of insulin and glucagon. Synonyms: Lys-Cys-Asn-Thr-Ala-Thr-Cys-Ala-Thr-Gln-Arg-Leu-Ala-Asn-Phe-Leu-Ile-Arg-Ser-Ser-Asn-Asn-Leu-Gly-Ala-Ile-Leu-Ser-Pro-Thr-Asn-Val-Gly-Ser-Asn-Thr-Tyr-NH2 (Disulfide bridge: Cys2-Cys7). Grades: ≥95%. Molecular formula: C165H270N52O54S2. Mole weight: 3910.45.
Amylin (rat)
Amylin (rat), islet Amyloid Polypeptide (IAPP), is a glucoregulatory peptide from rat pancreatic cells. It inhibits glucagon secretion, delays gastric emptying and acts as a satiety agent. It is used to study the regulation of satiety and obesity. It binds to heteromeric complexes of human calcitonin receptor 2 (CTR2) with receptor activity-modifying protein (RAMP) 1 or 3. It also binds to mouse α-thyroid-stimulating hormone thyrotroph (α-TSH) cells and rat nucleus accumbens membrane preparations. It inhibits insulin-induced, but not basal, glycogen synthesis in hepatocytes isolated from fasted rats in vitro. It does not form fibrils and is not cytotoxic unlike human amylin. It is active in vivo. Synonyms: Amylin, amide, rat; Amylin (mouse, rat); IAPP (mouse, rat); Islet amyloid polypeptide (mouse, rat); H-Lys-Cys(1)-Asn-Thr-Ala-Thr-Cys(1)-Ala-Thr-Gln-Arg-Leu-Ala-Asn-Phe-Leu-Val-Arg-Ser-Ser-Asn-Asn-Leu-Gly-Pro-Val-Leu-Pro-Pro-Thr-Asn-Val-Gly-Ser-Asn-Thr-Tyr-NH2; L-lysyl-L-cysteinyl-L-asparagyl-L-threonyl-L-alanyl-L-threonyl-L-cysteinyl-L-alanyl-L-threonyl-L-glutaminyl-L-arginyl-L-leucyl-L-alanyl-L-asparagyl-L-phenylalanyl-L-leucyl-L-valyl-L-arginyl-L-seryl-L-seryl-L-asparagyl-L-asparagyl-L-leucyl-glycyl-L-prolyl-L-valyl-L-leucyl-L-prolyl-L-prolyl-L-threonyl-L-asparagyl-L-valyl-glycyl-L-seryl-L-asparagyl-L-threonyl-L-tyrosinamide (2->7)-disulfide. Grades: ≥98%. CAS No. 124447-81-0. Molecular formula: C167H272N52O53S2. Mole weight: 3920.43.
Amylin (rat, mouse) trifluoroacetate salt
Amylin is a pancreatic β-cell hormone that produces effects in several different organ systems. Amylin is a 37-amino-acid peptide that activates its specific receptors, which are multisubunit G protein and resulting in multiple receptor subtypes. Amylin's major role is as a glucoregulatory hormone, and it is an important regulator of energy metabolism in health and disease. Amidated amylin increases the rate of glycogen synthesis induced by insulin in isolated rat soleus muscle when used at a concentration of 1 nM, while linear non-amidated amylin has no effect. Synonyms: IAPP (rat, mouse); Islet Amyloid Polypeptide (rat, mouse). Grades: ≥95%. Molecular formula: C167H272N52O53S2·xCF3COOH. Mole weight: 3920.40.
Amyloid β-peptide (1-40) rat
Amyloid β-peptide (1-40) (rat) is the rat form of the amyloid β-peptide found in plaques, which is the major constituent observed in the brain of Alzheimer's disease. It is the prone-to-aggregation product of amyloid precursor protein proteolytic cleavage. It is shown to have both neurotrophic and neurotoxic effects. Synonyms: β-Amyloid (1-40), rat; H-Asp-Ala-Glu-Phe-Gly-His-Asp-Ser-Gly-Phe-Glu-Val-Arg-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-OH; L-alpha-aspartyl-L-alanyl-L-alpha-glutamyl-L-phenylalanyl-glycyl-L-histidyl-L-alpha-aspartyl-L-seryl-glycyl-L-phenylalanyl-L-alpha-glutamyl-L-valyl-L-arginyl-L-histidyl-L-glutaminyl-L-lysyl-L-leucyl-L-valyl-L-phenylalanyl-L-phenylalanyl-L-alanyl-L-alpha-glutamyl-L-alpha-aspartyl-L-valyl-glycyl-L-seryl-L-asparagyl-L-lysyl-glycyl-L-alanyl-L-isoleucyl-L-isoleucyl-glycyl-L-leucyl-L-methionyl-L-valyl-glycyl-glycyl-L-valyl-L-valine; Rat amyloid-beta peptide 1-40; Rat amyloid-β peptide 1-40; Amyloid b-Protein (1-40) (Mouse, rat). Grades: ≥95%. CAS No. 144409-98-3. Molecular formula: C190H291N51O57S. Mole weight: 4233.76.
Amyloid β-peptide (1-42) human
Amyloid β-Peptide (12-28) (human), an Amyloid β-peptide fragment, binds with high affinity to α7-nicotinic ACh receptors. It impairs memory retention following central administration in mice. Uses: Implicated in alzheimer's disease. Synonyms: β-Amyloid (1-42), human; beta-Amyloid (1-42) human; Amyloid Beta Protein Fragment 1-42; H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala-OH; L-alpha-aspartyl-L-alanyl-L-alpha-glutamyl-L-phenylalanyl-L-arginyl-L-histidyl-L-alpha-aspartyl-L-seryl-glycyl-L-tyrosyl-L-alpha-glutamyl-L-valyl-L-histidyl-L-histidyl-L-glutaminyl-L-lysyl-L-leucyl-L-valyl-L-phenylalanyl-L-phenylalanyl-L-alanyl-L-alpha-glutamyl-L-alpha-aspartyl-L-valyl-glycyl-L-seryl-L-asparagyl-L-lysyl-glycyl-L-alanyl-L-isoleucyl-L-isoleucyl-glycyl-L-leucyl-L-methionyl-L-valyl-glycyl-glycyl-L-valyl-L-valyl-L-isoleucyl-L-alanine; Abeta 42 protein; amyloid beta-protein (1-42). Grades: ≥95%. CAS No. 107761-42-2. Molecular formula: C203H311N55O60S. Mole weight: 4514.04.
Amyloid β-peptide (1-42) (rat)
Amyloid β-peptide (1-42) (rat) is the rat form of the predominant amyloid β-peptide found in plaques associated with Alzheimer's disease. It could lead to a large shift in the bax/bcl-2 ratio in favour of pro-apoptotic bax. It is neurotoxic. Synonyms: Amyloid β-Protein (1-42) (mouse, rat); beta-Amyloid Peptide (1-42) (rat/mouse). CAS No. 166090-74-0. Molecular formula: C199H307N53O59S. Mole weight: 4418.02.
Amyloid beta-peptide (25-35)
Amyloid beta-peptide(25-35), the fragment Aβ(25-35) of the Alzheimer's amyloid β-peptide, is functionally required for the neurotrophic and neurotoxic effects associated with Alzheimer's disease. Synonyms: H-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-OH; glycyl-L-seryl-L-asparagyl-L-lysyl-glycyl-L-alanyl-L-isoleucyl-L-isoleucyl-glycyl-L-leucyl-L-methionine; Amyloid β-Protein (25-35); Amyloid-Protein (25-35). CAS No. 131602-53-4. Molecular formula: C45H81N13O14S. Mole weight: 1060.27.
Amyloid β-peptide (42-1) human
Amyloid β-peptide (42-1) (human), is the predominant form of amyloid β-peptide found in the brains of patients with Alzheimer's disease. Uses: Implicated in alzheimer's disease. Synonyms: H-Ala-Ile-Val-Val-Gly-Gly-Val-Met-Leu-Gly-Ile-Ile-Ala-Gly-Lys-Asn-Ser-Gly-Val-Asp-Glu-Ala-Phe-Phe-Val-Leu-Lys-Gln-His-His-Val-Glu-Tyr-Gly-Ser-Asp-His-Arg-Phe-Glu-Ala-Asp-OH; L-alanyl-L-isoleucyl-L-valyl-L-valyl-glycyl-glycyl-L-valyl-L-methionyl-L-leucyl-glycyl-L-isoleucyl-L-isoleucyl-L-alanyl-glycyl-L-lysyl-L-asparagyl-L-seryl-glycyl-L-valyl-L-alpha-aspartyl-L-alpha-glutamyl-L-alanyl-L-phenylalanyl-L-phenylalanyl-L-valyl-L-leucyl-L-lysyl-L-glutaminyl-L-histidyl-L-histidyl-L-valyl-L-alpha-glutamyl-L-tyrosyl-glycyl-L-seryl-L-alpha-aspartyl-L-histidyl-L-arginyl-L-phenylalanyl-L-alpha-glutamyl-L-alanyl-L-aspartic acid; Amyloid beta (42-1) human; Amyloid b-Protein (42-1). Grades: ≥95%. CAS No. 317366-82-8. Molecular formula: C203H311N55O60S. Mole weight: 4514.04.
Amyloid β-Protein 10-20
Amyloid β protein (10-20) is a fragment of Amyloid β peptide that may be used in the study of neurological diseases. Synonyms: H-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-OH; L-tyrosyl-L-alpha-glutamyl-L-valyl-L-histidyl-L-histidyl-L-glutaminyl-L-lysyl-L-leucyl-L-valyl-L-phenylalanyl-L-phenylalanine; Amyloid b-Protein (10-20); Amyloid B-protein fragment 10-20. Grades: ≥95%. CAS No. 152286-31-2. Molecular formula: C71H99N17O16. Mole weight: 1446.65.
Amylopectin - from maize
Amylopectin - from maize boasts its status as a paramount and environmentally sustainable byproduct obtained from maize starch. This versatile substance has been pervasively employed within the field of biomedical research due to its inherent biocompatibility and degradability. Serving as a formidable carrier for drug delivery systems and tissue engineering, its intricate composition exudes proficiency in encapsulating an array of pharmaceuticals, thus promoting precise release and optimized therapeutic effects. Synonyms: AMYLOPECTIN; 9037-22-3; (2R,3R,4S,5S,6R)-2-[(2R,3S,4R,5R,6S)-6-[[(2R,3S,4R,5R,6R)-4,5-dihydroxy-3-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-6-[(2R,3S,4R,5R,6S)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxan-2-yl]methoxy]-4,5-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol; Amylopectin - from maize; Amylopectine; SCHEMBL2046142; AKOS015916501; YA39745; YA164124; Q271643; (2R,3R,4S,5S,6R)-2-{[(2R,3S,4R,5R,6R)-2-({[(2S,3R,4R,5S,6R)-3,4-dihydroxy-6-(hydroxymethyl)-5-{[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}oxan-2-yl]oxy}methyl)-4,5-dihydroxy-6-{[(2R,3S,4R,5R,6S)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy}oxan-3-yl]oxy}-6-(hydroxymethyl)oxane-3,4,5-triol. CAS No. 9037-22-3. Molecular formula: (C6H10O5)n xH2O. Mole weight: 828.72.
Amylose
Amylose is a linear glucose polymer widely used in the biomedical industry utilized in the development of compound delivery systems, particularly for controlled release of compounds targeting various diseases. Synonyms: Polyamylose; α-Amylose; V Amylose; AS 30. CAS No. 9005-82-7. Molecular formula: (C6H10O5)n.
Amylostatin J
It is produced by the strain of Streptomyces diastaticus var. amylostaticus. It can inhibit the activity of Glucoamylase. CAS No. 79305-08-1. Molecular formula: C25H48NO15. Mole weight: 602.64.
Amylostatin K
It is produced by the strain of Streptomyces diastaticus var. amylostaticus. It can inhibit the activity of Glucoamylase. CAS No. 82642-64-6. Molecular formula: C25H43NO18. Mole weight: 645.61.
Amylostatin L
It is produced by the strain of Streptomyces diastaticus var. amylostaticus. It can inhibit the activity of Glucoamylase. CAS No. 82642-66-8. Molecular formula: C31H53NO23. Mole weight: 807.74.
Amylostatin M
It is produced by the strain of Streptomyces diastaticus var. amylostaticus. It can inhibit the activity of Glucoamylase. CAS No. 82642-67-9. Molecular formula: C31H53NO23. Mole weight: 807.74.
Amylostatin N
It is produced by the strain of Streptomyces diastaticus var. amylostaticus. It can inhibit the activity of Glucoamylase. CAS No. 82642-69-1. Molecular formula: C37H63NO28. Mole weight: 969.88.
Amylostatin XG 1-Thiophenyl Nonaacetate
Amylostatin XG 1-Thiophenyl Nonaacetate is a protected intermediate of Amylostatin XG, an analogue of an α-glucosidase inhibitor, Acarbose. Molecular formula: C43H55NO21S. Mole weight: 953.96.
Amylostatin XG Octaacetate
Amylostatin XG Octaacetate is a protected intermediate of Amylostatin XG, an analogue of an α-glucosidase inhibitor, Acarbose. Synonyms: [1S-(1α, 4α, 5β, 6α)]-4-O-[2, 3-Di-O-acetyl-4, 6-dideoxy-4-[[4, 5, 6-tris(acetyloxy)-3-[(acetyloxy)methyl]-2-cyclohexen-1-yl]amino]-α-D-glucopyranosyl]-D-glucopyranose. CAS No. 85747-82-6. Molecular formula: C39H53NO23. Mole weight: 903.83.
Amylostatin XG Octamethoxybenzyl Ether
Amylostatin XG Octamethoxybenzyl Ether is a protected intermediate of Amylostatin XG, an analogue of an α-glucosidase inhibitor, Acarbose. Molecular formula: C97H109NO21S. Mole weight: 1656.96.
Amythiamicin A
Amythiamicin A is a cyclic thiazole peptide produced by Amycolatopsis sp. MI 481-42F4A. It has antibacterial activity against gram-positive bacteria. Synonyms: MI 481-42F4A; Antibiotic MI 481-42F4A; NSC677423; Amythiamycin A. Grades: >98%. CAS No. 152741-89-4. Molecular formula: C50H51N15O8S6. Mole weight: 1182.43.
Amythiamicin B
It is produced by the strain of Amycolatopsis sp. M481-42F4. It has activity against gram-positive bacteria including Multidrug resistant Staphylococcus aureus and Methicillin-resistant Staphylococcus aureus (MR-SA)(MIC 0.1-0.78μg/mL). Not resistant to gram-negative bacteria and fungi. Synonyms: L-Prolinamide, N- ( (2- (10, 11, 17, 18, 23, 24, 25, 26, 27, 28-deca hydro-14- methyl -11- (2- ( methyl amino) -2-oxoethyl) -18, 28-bis (1- methyl ethyl) -9, 16, 23, 26-tetraoxo-9H, 16H-8, 5: 15, 12: 22, 19: 32, 29: 36, 33-pentanitri lo-5H, 29H, 33H-pyrido (3, 2-a1) (1, 11, 18, 25, 31, 4, 7, 14, 21) pentathiatetraazacyclotetratri acontin-2-yl) -4-thiazolyl) carbonyl) -L-seryl-. CAS No. 156620-48-3. Molecular formula: C50H53N15O9S6. Mole weight: 1200.44.
Amythiamicin C
It is produced by the strain of Amycolatopsis sp. M481-42F4. It has activity against gram-positive bacteria including Multidrug resistant Staphylococcus aureus and Methicillin-resistant Staphylococcus aureus (MR-SA)(MIC 0.1-0.78μg/mL). Not resistant to gram-negative bacteria and fungi. Synonyms: 4-Thiazolecarboxylic acid, 2- (10, 11, 17, 18, 23, 24, 25, 26, 27, 28-deca hydro-14- methyl -11- (2- methyl amino) -2-oxoethyl) -18, 28-bis (1- methyl ethyl) -9, 16, 23, 26-tetraoxo-9H, 16H-8, 5: 15, 12: 22, 19: 32, 29: 36, 33-pentanitri lo-5H, 29H, 33H-pyrido (3, 2-a1) (1, 11, 18, 25, 31, 4, 7, 14, 21) pentathiatetraazacyclotetratri acontin-2-yl) -, (octa hydro-1, 4-dioxopyrrolo (1, 2-a) pyrazin-3-yl) methyl ester. CAS No. 156620-47-2. Molecular formula: C50H50N14O9S6. Mole weight: 1183.41.
Amythiamicin D
It is produced by the strain of Amycolatopsis sp. M481-42F4. It has activity against gram-positive bacteria including Multidrug resistant Staphylococcus aureus and Methicillin-resistant Staphylococcus aureus (MR-SA)(MIC 0.1-0.78μg/mL). Not resistant to gram-negative bacteria and fungi. Synonyms: 4-Thiazolecarboxylic acid, 2- (10, 11, 17, 18, 23, 24, 25, 26, 27, 28-deca hydro-14- methyl -11- (2- ( methyl amino) -2-oxoethyl) -18, 28-bis (1- methyl ethyl) -9, 16, 23, 26-tetraoxo-9H, 16H-8, 5: 15, 12: 22, 19: 32, 29: 36, 33-pentanitri lo-5H, 29H, 33H-pyrido (3, 2-a1) (1, 11, 18, 25, 31, 4, 7, 14, 21) pentathiatetraazacyclotetratri acontin-2-yl) -, methyl ester. CAS No. 156620-46-1. Molecular formula: C43H42N12O7S6. Mole weight: 1031.26.