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angiotensin(1-12)
Angiotensin is a peptide hormone that causes vasoconstriction and an increase in blood pressure. Synonyms: ANGIOTENSIN (1-12) (MOUSE, RAT); ANGIOTENSINOGEN (1-12) (MOUSE, RAT); H-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-LEU-LEU-TYR-OH. Grades: 95%. CAS No. 914910-73-9. Molecular formula: C77H109N19O17. Mole weight: 1572.80.
angiotensin(2-7)
Angiotensin II is a medication that is used to treat hypotension resulting from septic shock or other distributive shock. CAS No. 100291-80-3. Molecular formula: C37H57N11O8. Mole weight: 783.92.
Angiotensin A
Angiotensin A is a potent endogenous vasoconstrictor octapeptide. It is a derivative of angiotensin II (Ang II) that differs from Ang II in having alanine instead of aspartic acid as the first amino acid. It shows similar affinity for AT1 and AT2 receptors as angiotensin II with Ki values of 1.6 and 2.3 nM in vitro. It causes pressor and renal vasoconstrictor effects in rodents by the AT1 receptor. It is inhibited by Candesartan but not by AT2 receptor ligands in vivo. It also increases inositol phosphate accumulation with a similar potency to Ang II with EC50 value of 6.7 nM. Synonyms: Ala-Angiotensin III; H-Ala-Arg-Val-Tyr-Ile-His-Pro-Phe-OH; Ang A; Angiotensin II, 1-L-alanine-5-L-isoleucine-; L-alanyl-L-arginyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-prolyl-L-phenylalanine. Grades: ≥95%. CAS No. 51833-76-2. Molecular formula: C49H71N13O10. Mole weight: 1002.18.
Angiotensin Acetate
Angiotensin acetate is an angiotensin II analog that is an agonist at angiotensin receptors. It is an oligopeptide and is a hormone and a powerful dipsogen. It is derived from the precursor molecule angiotensinogen, a serum globulin produced in the liver. It is a peptide hormone that causes vasoconstriction and a subsequent increase in blood pressure. It is part of the renin-angiotensin system, which is a major target for drugs that lower blood pressure. It plays an important role in the renin-angiotensin system. It also stimulates the release of aldosterone, another hormone, from the adrenal cortex. Uses: Angiotensin acetate causes vasoconstriction and a subsequent increase in blood pressure. it plays an important role in the renin-angiotensin system. Synonyms: ASP-ARG-VAL-TYR-VAL-HIS-PRO-PHE;H-ASP-ARG-VAL-TYR-VAL-HIS-PRO-PHE-OH;Angiotensin II 5-valine;Valine angiotensin II;5-L-Valine angiotensin II. Grades: 98%. CAS No. 58-49-1. Molecular formula: C49H69N13O12. Mole weight: 1032.15.
Angiotensin I human acetate salt hydrate
Angiotensin 1 (Human), an endogenous peptide substrate for angiotensin converting enzyme (ACE), is precursor to the vasoconstrictor peptide angiotensin II. Synonyms: H-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu-OH.CH3CO2H.H2O. CAS No. 70937-97-2. Molecular formula: C64H95N17O17. Mole weight: 1374.54.
Angiotensin I (human, mouse, rat)
Angiotensin 1 (Human), an endogenous peptide substrate for angiotensin converting enzyme (ACE), is precursor to the vasoconstrictor peptide angiotensin II. Synonyms: Angiotensin 1 Human; H-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu-OH; L-alpha-aspartyl-L-arginyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-prolyl-L-phenylalanyl-L-histidyl-L-leucine; Pepsitensin; Proangiotensin; 5-Ile-angiotensin I; 5-L-Isoleucine-angiotensin I. Grades: ≥95%. CAS No. 484-42-4. Molecular formula: C62H89N17O14. Mole weight: 1296.48.
Angiotensin I (human, rat, mouse) trifluoroacetate salt
Angiotensin I is formed from angiotensinogen by the action of renin, which is released from the kidney juxtaglomerular cells. Angiotensin I is further cleaved to angiotensin II by angiotensin converting enzyme. Angiotensin is a protein hormone that causes blood vessels to become narrower. It helps to maintain blood pressure and fluid balance in the body. It binds to angiotensin receptors in human myometrium membrane preparations with Kd of 11.2 nM and increases renal vascular resistance in isolated rat kidney with EC50 of 10.5 nM. Grades: ≥95%. Molecular formula: C62H89N17O14·xCF3COOH. Mole weight: 1296.48.
Angiotensin II
Angiotensin II is a Vasoconstrictor that plays an endocrine role in the regulation of blood pressure, fluid and electrolyte homeostasis. Synonyms: Hypertensin; Human angiotensin II; Ang II; Asp-Arg-Val-Tyr-X-His-Pro-Phe; L-alpha-aspartyl-L-arginyl-L-valyl-L-tyrosyl-X-L-histidyl-L-prolyl-L-phenylalanine; 1-8-Angiotensin I; Angiotensin 2; Angiotensin AT2; MeSH ID: D000804. CAS No. 11128-99-7.
Angiotensin II (1-4), human
Angiotensin II (1-4), human is an endogenous peptide produced from ATI by angiotensin-converting-enzyme (ACE). Synonyms: H-DRVY-OH; L-alpha-aspartyl-L-arginyl-L-valyl-L-tyrosine; (S)-3-amino-4-((S)-1-((S)-1-((S)-1-carboxy-2-(4-hydroxyphenyl)ethylamino)-3-methyl-1-oxobutan-2-ylamino)-5-guanidino-1-oxopentan-2-ylamino)-4-oxobutanoic acid; L-α-Aspartyl-N5-(diaminomethylene)-L-ornithyl-L-valyl-L-tyrosine. Grades: ≥95%. CAS No. 52580-29-7. Molecular formula: C24H37N7O8. Mole weight: 551.59.
Angiotensin II (3-8), human
Angiotensin II (3-8), human is a less effective agonist of the angiotensin AT1 receptor. Synonyms: 3-8-Angiotensin II; Angiotensin II, 1-de-L-aspartic acid-2-de-L-arginine-; Angiotensin IV; 3-8-Angiotensin; 3-8-Angiotensin II hexapeptide; Angiotensin II C-terminal hexapeptide; Angiotensin II3-8; Des-1,2-angiotensin II. Grades: ≥95%. CAS No. 12676-15-2. Molecular formula: C40H54N8O8. Mole weight: 774.91.
Angiotensin II (5-8), human
Angiotensin II (5-8), human is an endogenous C-terminal fragment of the peptide vasoconstrictor angiotensin II. Synonyms: Angiotensin (5-8); H-IHPF-OH; L-isoleucyl-L-histidyl-L-prolyl-L-phenylalanine; Angiotensin II (5-8) (human, rat, mouse). Grades: ≥95%. CAS No. 34233-50-6. Molecular formula: C26H36N6O5. Mole weight: 512.60.
Angiotensin I/II 1-5
Angiotensin I/II 1-5 is a peptide containing amino acids 1-5 that is converted from Angiotensin I/II. Synonyms: Angiotensin (1-5); H-DRVYI-OH; L-alpha-aspartyl-L-arginyl-L-valyl-L-tyrosyl-L-isoleucine; L-α-Aspartyl-N5-(diaminomethylene)-L-ornithyl-L-valyl-L-tyrosyl-L-isoleucine. Grades: ≥95%. CAS No. 58442-64-1. Molecular formula: C30H48N8O9. Mole weight: 664.75.
Angiotensin I/II 1-6
Angiotensin I/II 1-6 is a peptide containing amino acids 1-6 that is converted from Angiotensin I/II. Synonyms: H-Asp-Arg-Val-Tyr-Ile-His-OH; L-alpha-aspartyl-L-arginyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidine; Angiotensin (1-6); 1-6-Angiotensin II, 5-L-isoleucine-; Angiotensin 1/2 1-6; L-α-Aspartyl-N5-(diaminomethylene)-L-ornithyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidine. Grades: ≥95%. CAS No. 47896-63-9. Molecular formula: C36H55N11O10. Mole weight: 801.89.
Angiotensin I/II (1-7)
Angiotensin-(1-7) is an endogenous ligand for the G protein-coupled receptor, inducing vasorelaxation through release of NO and prostaglandins. Uses: Endogenous peptide fragment. Synonyms: Angiotensin II (1-7) heptapeptide; TXA127; TXA 127; TXA127; Angiotensin i (1-7); therapeutic angiotensin(17)H-Asp-Arg-Val-Tyr-Ile-His-Pro-OH. Grades: ≥90%. CAS No. 51833-78-4. Molecular formula: C41H62N12O11. Mole weight: 899.
Angiotensin I/II (3-7)
Angiotensin is a peptide hormone that causes vasoconstriction and an increase in blood pressure. Synonyms: ANGIOTENSIN I/II (3-7); H-VAL-TYR-ILE-HIS-PRO-OH; angiotensinii(3-7. Grades: 95%. CAS No. 122483-84-5. Molecular formula: C31H45N7O7. Mole weight: 627.73.
Angiotensin III (human, mouse)
Angiotensin III (Ang III) is generated from Ang II by APA (and subsequently degraded by aminopeptidase N), and that central Ang III seems to play a key-role in vasopressin release and BP control. Angiotensin III, human, mouse is a heptapeptide agonist, which acts as an endogenous angiotensin type 2 receptor (AT2R) agonist. The IC50 values for AT2R is 0.648 nM and the IC50 values for AT1R is 21.1 nM. The biologically active COOH-terminal heptapeptide angiotensin III is bound more tightly than angiotensin II. Synonyms: H-Arg-Val-Tyr-Ile-His-Pro-Phe-OH; L-arginyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-prolyl-L-phenylalanine; Ang III; Angiotensin III; 5-Ile-angiotensin III; 1-Desaspartyl-5-isoleucine angiotensin II; Des-asp(1)-(Ile(5))-angiotensin II; N5-(Diaminomethylene)-L-ornithyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-prolyl-L-phenylalanine; 2-8-angiotensin II, 5-L-isoleucine-. Grades: ≥95%. CAS No. 13602-53-4. Molecular formula: C46H66N12O9. Mole weight: 931.09.
Angiotensinogen (1-14), human
Angiotensinogen (1-14), human is a fragment of the renin substrate Angiotensinogen, a precursor for all angiotensin peptides. Synonyms: H-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu-Val-Ile-His-Asn-OH; L-alpha-aspartyl-L-arginyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-prolyl-L-phenylalanyl-L-histidyl-L-leucyl-L-valyl-L-isoleucyl-L-histidyl-L-asparagine; Renin Substrate Tetradecapeptide human. Grades: 95%. CAS No. 104180-23-6. Molecular formula: C83H122N24O19. Mole weight: 1760.00.
Angiotensinogen (1-14), Porcine
Angiotensin is a peptide hormone that causes vasoconstriction and an increase in blood pressure. Uses: Serine proteinase inhibitors. Synonyms: H-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-LEU-LEU-VAL-TYR-SER-OH; ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-LEU-LEU-VAL-TYR-SER; ANGIOTENSINOGEN FRAGMENT 1-14 PORCINE; ANGIOTENSINOGEN (1-14), PORCINE; ANGIOTENSINOGEN (1-14) (HORSE); ANGIOTENSINOGEN; PREANGIOTENSINOGEN (. Grades: 95%. CAS No. 64315-16-8. Molecular formula: C85H123N21O20. Mole weight: 1759.
Angiotensin is a peptide hormone that causes vasoconstriction and an increase in blood pressure. Synonyms: Hypertensinogen; Porcine renin substrate tetradecapeptide. CAS No. 20845-02-7. Molecular formula: C85H123N21O20. Mole weight: 1759.
Angolamycin
It is produced by the strain of Streptomyces eurythermus. It has anti-gram-positive bacteria activity and has effect on Mycoplasma pneumoniae Mac. Synonyms: Sincomycin A; Angolamycin, BRN 6045489; LS-19552; 2-[(14E)-9-[5-(4,5-dihydroxy-4,6-dimethyl-tetrahydropyran-2-yl)oxy-4-(dimethylamino)-6-methyl-tetrahydropyran-2-yl]oxy-3-ethyl-7-hydroxy-2-[(5-hydroxy-3,4-dimethoxy-6-methyl-tetrahydropyran-2-yl)oxymethyl]-8,12,16-trimethyl-5,13-dioxo-4,17-dioxabicyclo[14.1.0]heptadec-14-en-10-yl]acetaldehyde. CAS No. 1402-83-1. Molecular formula: C46H77NO17. Mole weight: 916.10.
Angstrom6
Angstrom6 is a urokinase inhibitor that can be used to treat chronic lymphocytic leukemia. Synonyms: A-6 peptide; A-6; A6; A 6. CAS No. 220334-14-5. Molecular formula: C39H62N10O15. Mole weight: 910.98.
Anguibactin
It is produced by the strain of Vibrio angullarum. It is an antibiotic that acts as a Siderophore and has a very strong affinity with Fe+3. Synonyms: (2Z)-N-hydroxy-2-(5-hydroxy-6-oxo-1-cyclohexa-2,4-dienylidene)-N-[2-(3H-imidazol-4-yl)ethyl]thiazolidine-4-carboxamide; ACMC-20m71m; (2Z)-N-hydroxy-2-(5-hydroxy-6-oxocyclohexa-2,4-dien-1-ylidene)-N-[2-(1H-imidazol-5-yl)ethyl]-1,3-thiazolidine-4-carboxamide. CAS No. 104245-09-2. Molecular formula: C15H16N4O4S. Mole weight: 348.38.
Anguidin
It is produced by the strain of Fusarium anguioides. It showed weak antifungal activity, and 0.03 μg/mL completely inhibited the mitosis of chicken embryo fibroblasts cultured in vitro. The inhibition rate of 0.51mg/kg/d in vivo for 7 consecutive days was 79%, 70% and 50%, respectively, for Walker cancer, sarcoma 37 and sarcoma 180 in rats. Synonyms: Diacetoxyscirpenol; Anguidine; 4,15-Diacetoxyscirpen-3-ol; CHEBI:4478; 4,15-Di-O-acetylscirpenol; Scirpenetriol 4,15-diacetate; NSC177378; ANG 66; 4,15-Diacetoxyscirp-9-en-3-ol; 4,15-Diacetoxyscirpenol; 12,13-Epoxytrichothec-9-ene-3alpha,4beta,15-triol 4,15-diacetate; 3-alpha-Hydroxy-4-beta,15-diacetoxy-12,13-epoxytrichothec-9-ene. Grades: ≥97%. CAS No. 2270-40-8. Molecular formula: C19H26O7. Mole weight: 366.40.
Anguinomycin A
It is produced by the strain of Streptomyces sp. R2827 and R2827-2. It has anti-rat Lewis lung cancer and P388 leukemia activity. It has been reported that it can cause normal cell growth to stop and deformable cell death. Synonyms: 5-Demethylleptomycin A, KR 2827A. Grades: >95% by HPLC. CAS No. 111278-01-4. Molecular formula: C31H44O6. Mole weight: 512.68.
Anguinomycin B
It is produced by the strain of Streptomyces sp. R2827 and R2827-2. It has anti-mouse Lewis lung cancer and P388 leukemia activity, and in vivo test shows that B has a strong anti-cancer effect on mouse solid cancer. It has been reported that it can stop normal cell growth and cause deformable cell death. Synonyms: KR-2827A; 2,10,12,16,18-Nonadecapentaenoic acid, 19-(3,6-dihydro-6-oxo-2H-pyran-2-yl)-17-ethyl-6-hydroxy-3,5,7,9,11,15-hexamethyl-8-oxo-. CAS No. 111278-00-3. Molecular formula: C32H46O6. Mole weight: 526.70.
It is produced by the strain of Streptomyces hygroscopicus var. angustmyceticus. It has anti-gram-positive bacteria and mycobacterium activity. Synonyms: decoyinine; Decoyinin; Antibiotic A14; 9-(6-Deoxy-beta-D-erythro-hex-5-en-2-ulofuranosyl)-9H-purin-6-amine; 9-(6-Deoxy-beta-D-erythro-hex-5-enulofuranosyl)adenine; 9-(Tetrahydro-3,4-dihydroxy-2-(hydroxymethyl)-5-methylene-2-furyl)adenine. Grades: ≥95%. CAS No. 2004-4-8. Molecular formula: C11H13N5O4. Mole weight: 279.25.
Angustmycin C
It is produced by the strain of Streptomyces hygroscopicus var. angustmyceticus. It has anti-gram-positive bacteria and mycobacterium activity, and has an inhibitory effect on Walker cancer 256 in rats and adenocarcinoma Ca755 in mice. Synonyms: Angustmycin C; NSC 53104; Psicofuranosyladenine; 1'-(Hydroxymethyl)adenosine; (2R,3R,4S,5R)-2-(6-aminopurin-9-yl)-2,5-bis(hydroxymethyl)oxolane-3,4-diol. Grades: ≥98%. CAS No. 1874-54-0. Molecular formula: C11H15N5O5. Mole weight: 297.27.
Anhydro-4-azido-5,6,8-tri-O-benzyl-1,2,4-trideoxy-D-glycero-D-gulo-oct-1-ynitol is a fascinating biomedical compound boasting immense potential in studying diverse diseases such as viral infections and cancers. Synonyms: 2-Azido-3,4,6-tri-O-benzyl-1,2-dideoxy-1-ethynyl-b-D-glucopyranose. CAS No. 443916-29-8. Molecular formula: C29H29N3O4. Mole weight: 483.56.
Anhydro abiraterone
An impurity of Abiraterone. Abiraterone acetate is a CYP17A1 inhibitor and by extension androgen synthesis inhibitor. In combination with prednisone, it is indicated for the treatment of patients with metastatic castration-resistant prostate cancer who have already received prior chemotherapy containing docetaxel under the trade name Zytiga. Synonyms: 3-Androsta-3,5,16-trien-17-yl-pyridine; 3-((8R,9S,10R,13S,14S)-10,13-Dimethyl-2,7,8,9,10,11,12,13,14,15-decahydro-1H-cyclopenta[a]phenanthren-17-yl)pyridine; 17-(3-Pyridyl)androsta-3,5,16-triene. Grades: 95%. CAS No. 154229-20-6. Molecular formula: C24H29N. Mole weight: 331.49.
Anhydrochlortetracycline
Anhydrochlortetracycline is an impurity in the tetracycline antibiotic chlortetracycline, which is formed from tetracycline in an acidic environment. Synonyms: Anhydroaureomycin. CAS No. 4497-8-9. Molecular formula: C22H21ClN2O7. Mole weight: 460.86.
Anhydrochlortetracycline hydrochloride
Anhydrochlortetracycline is a degradation product of chlorotetracycline formed by acid-catalysed isomerisation of the dimethylamino group at C4. It strongly inhibits the growth of Streptomyces aureofaciem, and shows a rather specific activity against actinomycetes. Synonyms: (4S,4aS,12aS)-7-Chloro-4-(dimethylamino)-1,4,4a,5,12,12a-hexahydro-3,10,11,12a-tetrahydroxy-6-methyl-1,12-dioxo-2-naphthacenecarboxamide Hydrochloride; Anhydroaureomycin Hydrochloride; Anhydro Chlortetracyline Monohydrochloride; [4S-(4α,4aα,12aα)]-7-Chloro-4-(dimethylamino)-1,4,4a,5,12,12a-hexahydro-3,10,11,12a-tetrahydroxy-6-methyl-1,12-dioxo-2-naphthacenecarboxamide Hydrochloride. Grades: >98% by HPLC. CAS No. 65490-24-6. Molecular formula: C22H22Cl2N2O7. Mole weight: 497.33.
Anhydroepiophiobolin A
Anhydroepiophiobolin A is an ophiobolin with a broad biological profile. It has antibacterial, antifungal, antitumour, herbicidal and nematocidal activities. It is the major terminal degradation product of ophiobolin A and is co-produced with other ophiobolins in many bipolaris species. Synonyms: (6α,18R)-14,18-epoxy-5-oxo-ophiobola-3,7,19-trien-25-al; (2'S, 3'S, 3aR, 5'R, 6aR, 9aS, 10aR)-2, 3a, 4, 4', 5', 6a, 7, 9a, 10, 10a-decahydro-3', 9, 10a-trimethyl-5'-(2-methyl-1-propen-1-yl)-7-oxospiro[dicyclopenta[a, d]cyclooctene-3(1H), 2'(3'H)-furan]-6-carboxaldehyde; 3-Anhydro-6-epi-ophiobolin A; [3S-[3α(3'R*, 5'S*), 3aα, 6aα, 9aβ, 10aβ]]-1, 3a, 4, 4', 5', 6a, 7, 9a, 10, 10a-decahydro-3', 9, 10a-trimethyl-5'-(2-methyl-1-propenyl)-7-oxospiro[dicyclopenta[a, d]cyclooctene-3(2H), 2'(3'H)-furan]-6-carboxaldehyde. Grades: >98% by HPLC. CAS No. 90411-20-4. Molecular formula: C25H34O3. Mole weight: 382.54.
Anhydroexfoliamycin
Anhydroexfoliamycin is a naphthoquinone antibiotic produced by Streptomyces exfoliamycin Tu 1424. Activity against gram-positive bacteria. CAS No. 148084-39-3. Molecular formula: C22H24O8. Mole weight: 416.42.
Anhydrofulvic acid
In acidic condition, Anhydrofulvic acid inhibits mitochondrial respiration of Candida utilis using both succinate and cytochrome C as respiratory substrates, but not using NADH. Anhydrofulvic acid has antifungal activity. Synonyms: 1H,10H-Pyrano[4,3-b][1]benzopyran-9-carboxylic acid, 7,8-dihydroxy-3-methyl-10-oxo-; 7,8-dihydroxy-3-methyl-10-oxo-1H-pyrano[4,3-b]chromene-9-carboxylic acid. CAS No. 95730-85-1. Molecular formula: C14H10O7. Mole weight: 290.23.
Anhydro Galantamine
Anhydro Galanthamine is an impurity of Galanthamine. Synonyms: (4aS,8aS)-9,10,11,12-Tetrahydro-3-Methoxy-11-Methyl-4aH-benzofuro[3a,3,2-ef][2]benzazepine; R 116937; TetrahydrogalantaMine; GalantaMine impurity D. Grades: > 95%. CAS No. 664995-65-7. Molecular formula: C17H19NO2. Mole weight: 269.35.
Anhydroophiobolin A
It is the dehydrated analogue of ophiobolin A and a major member of the ophiobolin complex of phytotoxic metabolites produced by many species of the genus bipolaris. It possesses a broad biological profile with antibacterial, antifungal, antitumour, herbicidal and nematocidal activities. Synonyms: 14,17-Epoxy-5-oxo-3,7,18-ophiobolatrien-21-al; Anhydroophiobolin; (18R)-5-Oxo-14,18-epoxy-3,4-didehydroophiobola-7,19-diene-25-al; (2'S, 3'S, 3aR, 5'R, 6aS, 9aS, 10aR)-2, 3a, 4, 4', 5', 6a, 7, 9a, 10, 10a-Decahydro-3', 9, 10a-trimethyl-5'-(2-methyl-1-propen-1-yl)-7-oxospiro[dicyclopenta[a, d]cyclooctene-3(1H), 2'(3'H)-furan]-6-carboxaldehyde; [3S-[3α(3'R*, 5'S*), 3aα, 6aβ, 9aβ, 10aβ]]-1, 3a, 4, 4', 5', 6a, 7, 9a, 10, 10a-Decahydro-3', 9, 10a-trimethyl-5'-(2-methyl-1-propenyl)-7-oxo-spiro[dicyclopenta[a, d]cyclooctene-3(2H), 2'(3'H)-furan]-6-carboxaldehyde; 3-Anhydro-cochliobolin; 3-Anhydroophiobolin A. Grades: >95% by HPLC. CAS No. 6026-65-9. Molecular formula: C25H34O3. Mole weight: 382.54.
Anhydrotetracycline hydrochloride
Anhydrotetracycline acts as an inducer of tetracycline resistance genes by binding to and inactivating the tetracycline repressor TetR to allow expression of downstream genes of the tetr promoter. However, anhydrotetracycline binds to the TetR repressor with higher affinity without toxic effects. Anhydrotetracycline poorly binds the 30S ribosomal subunit, the concentration of anhydrotetracycline that inhibits eukaryotic cell growth is more than 1,000-fold above the dose that alters transcription through TetR. Synonyms: (4S,4aS,12aS)-4-(Dimethylamino)-3,10,11,12a-tetrahydroxy-6-methyl-1,12-dioxo-1,4,4a,5,12,12a-hexahydro-2-tetracenecarboxamide hydrochloride (1:1). Grades: ≥98%. CAS No. 13803-65-1. Molecular formula: C22H22N2O7.HCl. Mole weight: 462.88.
Anhydrous Borax
Sodium Tetraborate, is an important boron compound, which has a wide variety of applications. It is a component of many detergents, cosmetics, and enamel glazes. It is also used to make buffer solutions in biochemistry, as a fire retardant, as an anti-fungal compound for fiberglass, as a flux in metallurgy, neutron-capture shields for radioactive sources, a texturing agent in cooking, and as a precursor for other boron compounds. Synonyms: Anhydrous borax; anhydrousborax; Antipyoninum; B4-Na2-O7; borates,tetra,sodiumsalt,anhydrous; borates, tetra, sodiumsalts(anhydrous); borates, tetra, sodiumsalts(pentahydrate); borax(anhydrous). Grades: fused. CAS No. 1330-43-4. Molecular formula: Na2B4O7. Mole weight: 201.21.
Ani 9
Ani 9 is a highly selective and potent anoctamin1 (ANO1)/transmembrane protein 16A (TMEM16A) inhibitor with IC50 value of 77 nM. It completely inhibits ANO1 chloride current with submicromolar potency and displays no effect on ANO2 activity at 10 μM. It does not affect the intracellular calcium signaling, or CFTR chloride channel activity and ENaC channel activity at 30 μM. It may be a useful pharmacological tool for studying ANO1. It may be potential for drug therapy of hypertension, cancer, diarrhea, asthma and pain. Synonyms: Ani9; Ani-9; Ani 9; (4-Chloro-2-methylphenoxy)-acetic acid [(2-methoxyphenyl)methylene]hydrazide; 2-(4-Chloro-2-methylphenoxy)-N-[(2-methoxyphenyl)methylideneamino]-acetamide; 2-(4-Chloro-2-methylphenoxy)-acetic acid 2-[(2-methoxyphenyl)methylene]hydrazide; 2-(4-Chloro-2-methylphenoxy)-N'-(2-methoxybenzylidene)acetohydrazide. Grades: ≥98% by HPLC. CAS No. 356102-14-2. Molecular formula: C17H17ClN2O3. Mole weight: 332.78.
Anicequol
It is produced by the strain of Penicillum aurantiogriseum Die-rckx TP-F0213. It can inhibit Colon cancer DLD-1 Cells that do not depend on adherent growth with IC50 of 1.2 μg/mL, and cells that depend on adherent growth with IC50 of 40 μg/mL. Synonyms: NGA0187; (3β, 5α, 7β, 11β, 24S)-16-acetoxy-3, 7, 11-trihydroxyergost-22-en-6-one. CAS No. 440368-05-8. Molecular formula: C30H48O6. Mole weight: 504.70.
a-Nicotinamide adenine dinucleotide phosphate
a-Nicotinamide adenine dinucleotide phosphate, commonly known as NADP+, stands as an indispensable coenzyme within the biomedical industry. Primarily responsible for driving cellular energy production and overseeing redox reactions, it assumes a vital role in numerous disease treatment modalities. Synonyms: a-NADP; a-Triphosphopyridine nucleotide; a-TPN; a-Nicotinamide adenine dinucleotide phosphate; sodium [[(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-3-hydroxy-4-phosphonooxyoxolan-2-yl]methoxy-oxidophosphoryl][(2R,3S,4R,5S)-5-(3-carbamoylpyridin-1-ium-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphate. Grades: 95%. CAS No. 108392-03-6. Molecular formula: C21H27N7NaO17P3. Mole weight: 765.39.
a-Nicotinamide mononucleotide
a-Nicotinamide mononucleotide is a pivotal intermediate in the bioresearch of nicotinamide adenine dinucleotide (NAD+), finding applications in studying the aging process and preserving neural integrity. Evidentially, it possesses the ability to stimulate sirtuin 1 is an NAD+-dependent enzyme, thereby augmenting mitochondrial functionality and fortifying cellular energy metabolism. Synonyms: 3-Carbamoyl-1-a-D-ribofuranosylpyridinium hydroxide,5'-phosphate, inner salt; α-nicotinamide mononucleotide; α-Nicotinamid-nucleotid; 3-carbamoyl-1-(O5-phosphono-α-D-ribofuranosyl)-pyridinium betaine; ((2R,3S,4R,5S)-5-(3-carbamoylpyridinium-1-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl hydrogen phosphate. CAS No. 7298-94-4. Molecular formula: C11H15N2O8P. Mole weight: 334.22.
Anidulafungin
Anidulafungin, is a semisynthetic echinocandin that inhibits glucan synthase, an enzyme important in the formation of (1?3)-β-D-glucan, a major fungal cell wall component, and thus is used as an antifungal drug. Synonyms: Eraxis; Ecalta; LY303366; 1-[(4R,5R)-4,5-dihydroxy-N2-[[4''-(pentyloxy)[1,1':4',1''-terphenyl]-4-yl]carbonyl]-L-ornithine]-echinocandin B. Grades: >98%. CAS No. 166663-25-8. Molecular formula: C58H73N7O17. Mole weight: 1140.24.
Anidulafungin Impurity A
Anidulafungin Impurity A is a degradation impurity of Anidulafungin, a semisynthetic echinocandin used as an antifungal drug. Anidulafungin has been used in the treatment of invasive fungal infections including candidiasis, candidemia and esophageal candidiasis. Synonyms: Anidulafungin Open-chain Degradant. Molecular formula: C58H73N7O17. Mole weight: 1140.25.
Anidulafungin Impurity B
Anidulafungin Impurity B is an impurity of Anidulafungin, a semisynthetic echinocandin used as an antifungal drug. Anidulafungin has been used in the treatment of invasive fungal infections including candidiasis, candidemia and esophageal candidiasis. Molecular formula: C57H71N7O17. Mole weight: 1126.23.
Anidulafungin Impurity C
Anidulafungin Impurity C is an impurity of Anidulafungin, a semisynthetic echinocandin used as an antifungal drug. Anidulafungin has been used in the treatment of invasive fungal infections including candidiasis, candidemia and esophageal candidiasis. Molecular formula: C57H71N7O17. Mole weight: 1126.23.
Anidulafungin Impurity D
Anidulafungin Impurity D is an impurity of Anidulafungin, a semisynthetic echinocandin used as an antifungal drug. Anidulafungin has been used in the treatment of invasive fungal infections including candidiasis, candidemia and esophageal candidiasis. Molecular formula: C59H75N7O17. Mole weight: 1154.28.
Anidulafungin Impurity E
Anidulafungin Impurity E is an impurity of Anidulafungin, a semisynthetic echinocandin used as an antifungal drug. Anidulafungin has been used in the treatment of invasive fungal infections including candidiasis, candidemia and esophageal candidiasis. Molecular formula: C57H71N7O17. Mole weight: 1126.23.
Anidulafungin Impurity F
Anidulafungin Impurity F is an impurity of Anidulafungin, a semisynthetic echinocandin used as an antifungal drug. Anidulafungin has been used in the treatment of invasive fungal infections including candidiasis, candidemia and esophageal candidiasis. Molecular formula: C82H95N7O19. Mole weight: 1482.69.
Aniline-[1-13C]
Synonyms: Aniline-1-13C. Grades: 99% by CP; 99% atom 13C. CAS No. 18960-62-8. Molecular formula: C5[13C]H7N. Mole weight: 94.12.
Aniline-[13C6]
Synonyms: 13C Labeled aniline; Aminobenzene-13C6; Benzeneamine-13C6; Phenylamine-13C6; Aniline-13C6. Grades: 99% by CP; 99% atom 13C. CAS No. 100849-37-4. Molecular formula: [13C]6H5NH2. Mole weight: 99.08.
Aniline β-D-Glucuronide
A metabolite of Aniline. Arylamines are predominantly conjugated by constitutive enzyme forms in the liver. Uses: A metabolite of aniline. arylamines are predominantly conjugated by constitutive enzyme forms in the liver. Synonyms: 1-Deoxy-1-(phenylamino)-β-D-glucopyranuronic Acid. CAS No. 92117-30-1. Molecular formula: C12H15NO6. Mole weight: 269.25.
Anionic antimicrobial peptide 2, partial
Anionic antimicrobial peptide 2, partial is an antimicrobial peptide produced by Galleria mellonella. It has antimicrobial activity. Synonyms: Thr-Lys-Asn-Phe-Asn-Thr-Gln-Val-Gln-Asn-Ala-Phe-Asp-Ser-Asp-Lys-Ile-Lys-Ser-Glu-Val-Asn-Asn-Phe-Ile-Glu-Ser-Leu-Gly-Lys-Ile-Leu-Asn-Thr-Glu-Lys-Lys-Glu-Ala-Pro-Lys. Grades: >98%.
Anionic peptide SAAP
Anionic peptide SAAP is an antimicrobial peptide produced by Pasteurella haemolytica. It has antibacterial activity. Synonyms: Asp-Asp-Asp-Asp-Asp-Asp. Grades: >95%. Molecular formula: C24H32N6O19. Mole weight: 708.54.
Anionic polyacrylamide
Cas No. 25038-45-3.
Aniracetam
Aniracetam is a nootropics and neuroprotective drug. Synonyms: Aniracetam; Ampamet; Ro-13-5057; Ro 13 5057; Ro135057; Draganon; Sarpul. Grades: >98%. CAS No. 72432-10-1. Molecular formula: C12H13NO3. Mole weight: 219.24.
Anisaldehyde-[13C]
Anisaldehyde-[13C] is the labelled analogue of Anisaldehyde, which is a metabolic product of the odoriferous fungus Lentinus lepidus. Anisaldehyde is used in perfumery and toilet soaps. Synonyms: Anisaldehyde-13C; p-Anisaldehyde-13C; 4-Anisaldehyde-13C; Anisic Aldehyde-13C; Aubepine-13C; Crategine-13C; NSC 5590-13C; Obepin-13C; p-Anisic Aldehyde-13C; p-Formylanisole-13C; p-Methoxybenzaldehyde-13C; Anisaldehyde-7-13C. Grades: ≥97%; ≥95% atom 13C. CAS No. 95537-93-2. Molecular formula: C7[13C]H8O2. Mole weight: 137.14.
Anisindione
Anisindione, an anticoagulant, could avoid the generation of active procoagulation factors and sorts of proteins in the liver. Uses: Anisindione is an anticoagulant and could avoid the generation of active procoagulation factors and sorts of proteins in the liver. Synonyms: Anisindione; Miradon; Anisin indandione; Unidone; 2-(4-Methoxyphenyl)-1H-indene-1,3(2H)-dione. Grades: 98%. CAS No. 117-37-3. Molecular formula: C16H12O3. Mole weight: 252.26.
Anisole-[2,3,4,5,6-d5]
Synonyms: Methoxy(benzene-d5); Anisole-2,3,4,5,6-d5. Grades: 99% by CP; 98% atom D. CAS No. 50629-14-6. Molecular formula: C7H3D5O. Mole weight: 113.17.
Anisomycin
It is produced by the strain of Streptomyces griseolus. It inhibits protein synthesis. it has anti-fungal, anti-fine bacteria, anti-tumor and antigenic insect action. Synonyms: Flagecidin; NSC-76712; AI3-50846; NSC76712; AI350846; NSC 76712; AI3 50846. Grades: ≥98%. CAS No. 22862-76-6. Molecular formula: C14H19NO4. Mole weight: 265.30.
Anisotropine methyl bromide
Cas No. 80-50-2.
Ankaflavin
A pigment hs more anti-atherosclerosis effect and less side effect involving increasing creatinine phosphokinase activity. Synonyms: 2H-Furo[3,?2-g]?[2]?benzopyran-2,?9(3H)?-dione, 3a,?4,?8,?9a-tetrahydro-9a-methyl-3-(1-oxooctyl)?-6-(1E)?-1-propen-1-yl-, (3S,?3aR,?9aR)?-. Grades: > 95%. CAS No. 50980-32-0. Molecular formula: C23H30O5. Mole weight: 386.49.
Ankyrin repeat domain-containing protein 11 (421-433)
Ankyrin repeat domain-containing protein 11 (421-433) is a fragment of Ankyrin repeat domain-containing protein 11. This protein contains multiple regions called ankyrin domains; proteins with these domains help other proteins interact with each other. Synonyms: Ankyrin repeat-containing cofactor 1 (421-433).
Ankyrin repeat domain-containing protein 26 isoform 2 (168-183)
Ankyrin repeat domain-containing protein 26 isoform 2 (168-183) is a truncated fragment of Ankyrin repeat domain-containing protein 26 isoform 2. Ankyrin repeat domain-containing protein 26 acts as a regulator of adipogenesis. Involved in the regulation of the feeding behavior.
Ankyrin repeat domain-containing protein 30A (904-912)
Ankyrin repeat domain-containing protein 30A (904-912) is amino acids 904 to 912 fragment of Ankyrin repeat domain-containing protein 30A, which is a DNA-binding transcription factor that is uniquely expressed in mammary epithelium and the testis. And the altered expression levels have been associated with breast cancer progression. Synonyms: Serologically defined breast cancer antigen NY-BR-1 (904-912).
Anle138b
Anle138b is a novel fluorescent oligomer modulator and an aggregation inhibitor. In vitro, anle138b blocked the formation of pathological aggregates of prion protein (PrPSc) and of α-synuclein. Synonyms: Anle138b; Anle 138b; Anle-138b; 5-(1,3-benzodioxol-5-yl)-3-(3-bromophenyl)-1H-pyrazole; 3-(1,3-benzodioxol-5-yl)-5-(3-bromophenyl)-1H-pyrazole; anle138b. CAS No. 882697-00-9. Molecular formula: C16H11BrN2O2. Mole weight: 343.17.
Anlotinib
Anlotibib is a multi-targetes kinase inhibitor of receptor tyrosine and could effectively resist the formation of new angiogenesis. It is undergoing a phase III clinical trial for therapy of metastatic or advanced alveolar soft part sarcoma (ASPS), leiomyosarcoma (LMS), and synovial sarcoma (SS). Synonyms: 1-[[4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-6-methoxyquinolin-7-yl]oxymethyl]cyclopropan-1-amine. Grades: >98%. CAS No. 1058156-90-3. Molecular formula: C23H22FN3O3. Mole weight: 407.445.
Anlotinib Dihydrochloride
Anlotinib Dihydrochloride is a novel multi-target tyrosine kinase inhibitor with potential antineoplastic and anti-angiogenic activities, which was designed to primarily inhibit VEGFR2/3, FGFR1-4, PDGFRα/β, c-Kit, and Ret. Synonyms: 1- [ [ [4- [ (4-fluoro-2-methyl-1H-indol-5-yl) oxy] -6-methoxy-7-quinolinyl] oxy] methyl] cyclopropanamine Hydrochloride (1:2); AL3818 Dihydrochloride; Anlotinib 2HCl; AL3818 2HCl. CAS No. 1360460-82-7. Molecular formula: C23H22FN3O3.2ClH. Mole weight: 480.36.
Annatto
Annatto is a colorant and opacifier. Synonyms: Annatto extract. CAS No. 1393-63-1. Molecular formula: C24H28O4. Mole weight: 380.48.