BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
CaO (CaO), commonly known as quicklime or burnt lime, is a widely used chemical compound. It is a white, caustic, alkaline, crystalline solid at room temperature. The broadly used term "lime" connotes calcium-containing inorganic materials, in which carbonates, oxides and hydroxides of calcium, silicon, magnesium, aluminium, and iron predominate. By contrast, "quicklime" specifically applies to the single chemical compound CaO. Uses: Food additive, anticaking agent, firming agent, nutritive supplement. Synonyms: Lime; Calcia; airlock; bellcml; CAUSTIC. Grade: 90%. CAS No. 1305-78-8. Molecular formula: CaO. Mole weight: 56.0774.
Calcium Oxide
Calcium Oxide can be used as a solvent in textile and chemical fabrication processes. Synonyms: Lime Oxide. CAS No. 73018-51-6. Molecular formula: CaO. Mole weight: 56.077.
Calcium Silicate
Calcium silicate is used as an auxiliary filler for oral pharmaceuticals. It is also used as an antacid in pharmaceutical preparations, and as an anti-caking agent. Synonyms: Silicic acid, calcium salt; Advacate; Calcium hydrosilicate; Calcium monosilicate; Calcium polysilicate; Calsil; Calsilite; Ecolux; Florite; Silasorb (celite); Taikalit; Taikalite; Zeodent 250. Grade: 95%. CAS No. 1344-95-2.
Calcium silicate (1:1)
Calcium silicate (1:1) is used as an auxiliary filler for oral pharmaceuticals. It is also used as an antacid in pharmaceutical preparations, and as an anti-caking agent. Synonyms: Silicic acid (H2SiO3), calcium salt (1:1); Baysical K; C.I. 77230; C.I. Pigment White 28; Calcium metasilicate; Calcium silicate (Ca0.5(SiO3)0.5); Calcium silicate (Ca2(SiO3)2); Calcium silicate (CaSiO3); Calcium silicon oxide (CaSiO3); Casiflux A 25; CS (cement component); Denacup 325-1100; Kemolit 1025; Kemolit ASB 8K; Nyad M 400; Pigment White 28; Sorbosil CA 40; Ultrasil 880; Wollastocoat 10AS; Wollastocoat 10ES; β-Calcium silicate (CaSiO3). Grade: 99%. CAS No. 10101-39-0. Molecular formula: CaO3Si. Mole weight: 116.17.
Calcium zirconium isopropoxide, 10% w/v in isopropanol
Calcium zirconium isopropoxide, 10% w/v in isopropanol. Synonyms: CALCIUM ZIRCONIUM ISOPROPOXIDE; Calcium zirconium isopropoxide, 10% w/v in isopropanol. CAS No. 334512-82-2. Molecular formula: CaZr[OCH(CH3)2]6. Mole weight: 485.82448.
Calicheamicin
Calicheamicins are a class of enediyne antitumor antibiotics derived from the bacterium Micromonospora echinospora, The main component is calicheamicin γ1. It has strong anti-Gram-positive bacteria activity and anti-tumor effect. Uses: Adcs cytotoxin. Synonyms: calicheamicin γ1. Grade: ≥95% by HPLC. CAS No. 108212-75-5. Molecular formula: C55H74IN3O21S4. Mole weight: 1368.35.
Calmodulin-Dependent Protein Kinase II 290-309
Calmodulin-dependent protein kinase II (290-309) is a synthetic peptide derived from the rat brain protein sequence that contains the calmodulin binding domain. It inhibits calcium/calmodulin-dependent protein kinase II (CaMKII) with IC50 of 52 nM and CaMKII-dependent phosphodiesterase activity with IC50 of 1.1 nM. It has been used in the study of CaM binding, autophosphorylatio and dynamics. Synonyms: Leu-Lys-Lys-Phe-Asn-Ala-Arg-Arg-Lys-Leu-Lys-Gly-Ala-Ile-Leu-Thr-Thr-Met-Leu-Ala; L-leucyl-L-lysyl-L-lysyl-L-phenylalanyl-L-asparagyl-L-alanyl-L-arginyl-L-arginyl-L-lysyl-L-leucyl-L-lysyl-glycyl-L-alanyl-L-isoleucyl-L-leucyl-L-threonyl-L-threonyl-L-methionyl-L-leucyl-L-alanine; CaM kinase II (290-309); Calmodulin-dependent Protein Kinase II fragment 290-309. Grade: ≥97% by HPLC. CAS No. 115044-69-4. Molecular formula: C103H185N31O24S. Mole weight: 2273.83.
Caloxin 2A1
Caloxin 2A1 is a selective extracellular peptide inhibitor of the plasma membrane Ca2+-ATPase (PMCA). It has no effect on basic Mg2+-ATPase or Na+-K+-ATPase. Synonyms: H-Val-Ser-Asn-Ser-Asn-Trp-Pro-Ser-Phe-Pro-Ser-Ser-Gly-Gly-Gly-NH2; L-valyl-L-seryl-L-asparagyl-L-seryl-L-asparagyl-L-tryptophyl-L-prolyl-L-seryl-L-phenylalanyl-L-prolyl-L-seryl-L-seryl-glycyl-glycyl-glycinamide; Glycinamide, L-valyl-L-seryl-L-asparaginyl-L-seryl-L-asparaginyl-L-tryptophyl-L-prolyl-L-seryl-L-phenylalanyl-L-prolyl-L-seryl-L-serylglycylglycyl-. Grade: ≥95%. CAS No. 350670-85-8. Molecular formula: C64H91N19O22. Mole weight: 1478.54.
CALP2
CALP2 is a cell-permeable calmodulin (CaM) antagonist binding to the EF-hand/Ca2+-binding site. CALP2 exhibits an inhibitory effect on CaM-dependant phosphodiesterase activity, and leads to an increase on intracellular Ca2+ level by modulating Ca2+-channel activity. CALP2 was also shown to be a potent activator of alveolar macrophages. Synonyms: Calcium-like peptide 2. CAS No. 261969-04-4. Molecular formula: C68H104N14O13S. Mole weight: 1357.72.
CALP3
CALP3 is a cell-permeable calmodulin (CaM) agonist binding to the EF-hand/Ca2+-binding site. It activates phosphodiesterase in the absence of Ca2+ and suppresses Ca2+-mediated cytotoxicity and apoptosis (IC50 = 33 μM). Synonyms: Calcium-like peptide 3. CAS No. 261969-05-5. Molecular formula: C44H68N10O9. Mole weight: 881.08.
CALP3 acetate
CALP3 acetate is a potent Ca2+ channel blocker that mimics [Ca2+]i increase by regulating the activity of calmodulin (CaM), Ca2+ channels, and pumps. CALP3 is a cell-permeable calmodulin (CaM) agonist binding to the EF-hand/Ca2+-binding site. Synonyms: H-Val-Lys-Phe-Gly-Val-Gly-Phe-Lys-OH.CH3CO2H; L-valyl-L-lysyl-L-phenylalanyl-glycyl-L-valyl-glycyl-L-phenylalanyl-L-lysine acetic acid; CALP 3 acetate; CALP-3 acetate; Calcium-like peptide 3 acetate. Grade: ≥95%. Molecular formula: C46H72N10O11. Mole weight: 941.12.
CALP3 trifluoroacetate salt
CALP3 is a calcium-like peptide that contains the first eight residues of CALP2, which is a 12-residue peptide that interacts with EF hand motif 4 in human calmodulin to activate it in the absence of calcium. It acts as a cell-permeable inhibitor of calcium influx through glutamate receptor channels in cultured rat neocortical neurons with IC50 of 37.25 μM. It also inhibits excitatory cytotoxicity with IC50 of 50.97 μM and apoptosis with IC50 of 33.41 μM. CALP3 was used to study as a new type of Ca2+ channel blocker that targets Ca2+ sensors and prevents Ca2+-mediated apoptosis. Synonyms: H-Val-Lys-Phe-Gly-Val-Gly-Phe-Lys-OH.TFA; L-valyl-L-lysyl-L-phenylalanyl-glycyl-L-valyl-glycyl-L-phenylalanyl-L-lysine trifluoroacetate; CALP 3 trifluoroacetate; CALP-3 trifluoroacetate; CALP3 TFA; CALP 3 TFA; CALP-3 TFA; Calcium-like peptide 3 TFA. Grade: ≥98%. Molecular formula: C46H69F3N10O11. Mole weight: 995.11.
Calvatic acid
Calvatic acid is an antibiotic produced by Calvatia craniformis (Shw.) Fr. It has anti-gram-positive and negative bacteria (weak) activity, and inhibits Yoshida sarcoma and L-1210 cell activity. Synonyms: p-Carboxyphenylazoxycyanide; Benzoic acid, 4-(cyano-NNO-azoxy)-. CAS No. 54723-08-9. Molecular formula: C8H5N3O3. Mole weight: 191.14.
Camstatin
Camstatin, an analog of PEP-19, has been found to have enhanced activities binding to and antagonism of calmodulin. Synonyms: Camstatin; 1002295-95-5; AKOS024458712; PD078973; S-1002295-95-5. Grade: ≥95% by HPLC. CAS No. 1002295-95-5. Molecular formula: C122H203N39O34. Mole weight: 2760.19.
Candicidin D
Candicidin is a heptaene macrolide antibiotic produced by Streptomyces griseus. It has antifungal activity and is used as a topical antifungal. Synonyms: Candizidin; Candicidin D1; Levorin A2. CAS No. 39372-30-0. Molecular formula: C59H84N2O18. Mole weight: 1109.30.
Candidin
Candidin is a heptaene macrolide antifungal antibiotic produced by Streptomyces viridoflavue. It has antibacterial properties against Candida albicans, Trichophyton, Blastomyces dermatitis, Schenker's side mold, and Pestle mold, etc. Synonyms: Amphotericin B, 8,9-dideoxy-10-hydroxy-7-oxo-; Candidin. Grade: 95%. CAS No. 1405-90-9. Molecular formula: C47H71NO17. Mole weight: 922.06.
c-(Ap-8-Biotin-11-Gp)
c-(Ap-8-Biotin-11-Gp) is an analogue of the cyclic dinucleotide c-(ApGp). It is a potential tracer in immunoassays and commonly used for affinity chromatography and pull-down assays. Grade: ≥ 95% by HPLC. Molecular formula: C38H54N14O16P2S2 (free acid). Mole weight: 1089 (free acid).
Capecitabine
Capecitabine inhibits tumor growth and metastatic recurrence after resection of human hepatocellular carcinoma (HCC) in highly metastatic nude mice model. It is a chemotherapy medication used to treat breast cancer, gastric cancer and colorectal cancer. Synonyms: 5'-Deoxy-5-fluoro-N-[(pentyloxy)carbonyl]cytidine; [1-(5-Deoxy-β-D-ribofuranosyl)-5-fluoro-1,2-dihydro-2-oxo-4-pyrimidinyl]carbamic Acid Pentyl Ester; Capecytabine; Capiibine; Captabin; Ro 09-1978; Xeloda; Pentyl 1-(5-deoxy-beta-D-ribofuranosyl)-5-fluoro-1,2-dihydro-2-oxo-4-pyrimidinecarbamate. Grade: ≥98% by HPLC. CAS No. 154361-50-9. Molecular formula: C15H22FN3O6. Mole weight: 359.35.
Caprazamycin
Caprazamycin is a liponucleoside antibiotic isolated from Streptomyces sp. MK730-62F2. CAS No. 327164-11-4. Molecular formula: C53H87N5O22. Mole weight: 1146.28.
Capreomycin
Capreomycin is a peptide antibiotic produced by Streptomyces capreolus. Anti-mycobacteria. Synonyms: Capromycin, Caprolin, Capastat, Capostatin, L 29275. Grade: >99% by HPLC. CAS No. 11003-38-6. Molecular formula: C50H88N28O15. Mole weight: 1321.41.
Capreomycin sulfate
Capreomycin sulfate is a salt of a complex of cyclic pentopeptides isolated from streptomyces capreolus. It is an antibiotic with potent anti-tuberculosis activity. Synonyms: Kapreomycin; Capostatin; HSDB 3211; HSDB-3211; HSDB3211; Capastat sulfate; Caprocin sulfate; (2S)-2,5-diamino-N-(((2S,5R,11S,15R,Z)-15-amino-11-(2-amino-3,4,5,6-tetrahydropyrimidin-4-yl)-2-(hydroxymethyl)-3,6,9,12,16-pentaoxo-8-(ureidomethylene)-1,4,7,10,13-pentaazacyclohexadecan-5-yl)methyl)pentanamide, monosulfate. Grade: ≥95%. CAS No. 1405-37-4. Molecular formula: C24H42N14O8.H2SO4. Mole weight: 752.76.
Capsimycin
Capsimycin is an antifungal antibiotic produced by Streptomyces sp. C 49-87. It has antifungal activity, especially against Phytophthora capsici. CAS No. 70694-08-5. Molecular formula: C30H40N2O6. Mole weight: 524.65.
Carbadox is a broad-spectrum antimicrobial agent. Synonyms: Mecadox. CAS No. 6804-7-5. Molecular formula: C11H10N4O4. Mole weight: 262.22.
Carbazomycin A
Carbazomycin A is a nitrogen-containing heterocyclic antibiotic produced by streptomyces H-1051-MY 10, which weakly inhibits a few fungi and bacteria. Synonyms: 4-O-Methylcarbazomycin B; 9H-Carbazole, 3,4-dimethoxy-1,2-dimethyl-. CAS No. 75139-39-8. Molecular formula: C16H17NO2. Mole weight: 255.31.
Carbazomycin B
Carbazomycin B is a nitrogen-containing heterocyclic antibiotic produced by streptomyces H-1051-MY 10. It can inhibit a variety of plant pathogenic fungi, and has weak anti-bacterial and anti-yeast activity. Synonyms: 1,2-Dimethyl-3-methoxy-9H-carbazol-4-ol. CAS No. 75139-38-7. Molecular formula: C15H15NO2. Mole weight: 241.28.
Carbenicillin
It is produced by the strain of Semisynthetic penicillin, 6-APA. Carbenicillin is a broad-spectrum semisynthetic penicillin derivative used parenterally. It is a semi-synthetic penicillin antibiotic which interferes with cell wall synthesis of gram-negative bacteria while displaying low toxicity. It is used to treat pseudomonas aeruginosa infection. Synonyms: Carboxybenzylpenicillin; alpha-Carboxybenzylpencillin; Carbenicilina; Carbenicilline; Carbenicillinum; Pyopen; Carboxybenzylpenicillin acid; CBPC; Geopen. Grade: >98%. CAS No. 4697-36-3. Molecular formula: C17H18N2O6S. Mole weight: 378.40.
Carbetocin is a potent agonist of the oxytocin receptor, with improved in vivo stability over oxytocin. Synonyms: Glycinamide, N-(4-mercapto-1-oxobutyl)-O-methyl-L-tyrosyl-L-isoleucyl-L-glutaminyl-L-asparaginyl-L-cysteinyl-L-prolyl-L-leucyl-, cyclic (1→5)-thioether; 1-Carbaoxytocin, 1-butanoic acid-2-(O-methyl-L-tyrosine)-; [2-O-Methyltyrosine]-deamino-1-carba-oxytocin; [Desamino-monocarba1,Tyr(methyl)2]-oxytocin; Deamino-2-O-methyltyrosine-1-carbaoxytocin; Depotocin; Duratocin; LV 101; LV 101 (Intranasal carbetocin); Pabal; But-Tyr(Me)-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2 (Thioether bridge: But1-Cys6); Butyryl-O-methyl-L-tyrosyl-L-isoleucyl-L-glutaminyl-L-asparagyl-L-cysteinyl-L-prolyl-L-leucyl-glycinamide (1->6)-thioether; 1-Butyric acid-2-(3-(p-methoxyphenyl)-L-alanine)oxytocin. Grade: >98%. CAS No. 37025-55-1. Molecular formula: C45H69N11O12S. Mole weight: 988.16.
Carbidopa
Carbidopa is an aromatic-L-amino-acid decarboxylase inhibitor with an IC50 of 29 ± 2 μM. Uses: Antiparkinson agents. Synonyms: α-Methyldopahydrazine; (S)-3-(3,4-Dihydroxyphenyl)-2-hydrazino-2-methylpropanoic acid; N-amino-alpha-methyl-3-hydroxy-L-tyrosine; (S)-α-Hydrazino-3,4-dihydroxy-α-methylbenzenepropanoic acid; (-)-L-α-Hydrazino-3,4-dihydroxy-α-methylhydrocinnamic acid; (S)-(-)-Carbidopa; (αS)-α-Hydrazino-3,4-dihydroxy-α-methylbenzenepropanoic Acid; (S)-Carbidopa; 1-α-(3,4-Dihydroxybenzyl)-α-hydrazinopropionic Acid; HMD; Hydrazino-α-methyldopa; Lodosin; Lodosyn; MK 486; N-Aminomethyldopa. Grade: >98%. CAS No. 28860-95-9. Molecular formula: C10H14N2O4. Mole weight: 226.23.
Carbidopa Hydrate
Carbidopa Hydrate is a hydrate form of Carbidopa. Carbidopa is an aromatic-L-amino-acid decarboxylase inhibitor with an IC50 of 29 ± 2 μM. It inhibits the conversion of levodopa to dopamine. Uses: Antiparkinson agents. Synonyms: α-Methyldopahydrazine monohydrate; (S)-3-(3,4-Dihydroxyphenyl)-2-hydrazino-2-methylpropanoic acid monohydrate; N-amino-alpha-methyl-3-hydroxy-L-tyrosine monohydrate; (S)-α-Hydrazino-3,4-dihydroxy-α-methylbenzenepropanoic acid monohydrate; (-)-L-α-Hydrazino-3,4-dihydroxy-α-methylhydrocinnamic acid monohydrate; Lodosin monohydrate; Lodosyn monohydrate; MK 486 monohydrate; N-Aminomethyldopa monohydrate; (S)-(-)-Carbidopa monohydrate. Grade: ≥95%. CAS No. 38821-49-7. Molecular formula: C10H14N2O4.H2O. Mole weight: 244.25.
(+/-)-Carbinoxamine Maleate-[N,N-dimethyl-d6]
(+/-)-Carbinoxamine Maleate-[N,N-dimethyl-d6], is the labelled analogue of Carbinoxamine Maleate. Carbinoxamine maleate is an impurity of Carbinoxamine, which is an analgesic and anti-inflammatory compound. Synonyms: (2Z)-but-2-enedioic acid; {2-[(4-chlorophenyl)(pyridin-2-yl)methoxy]ethyl}bis(D3)methylamine; (+/-)-Carbinoxamine D6 Maleate (N,N-dimethyl-d6); (±)-2-[(4-Chlorophenyl)-2-pyridinylmethoxy]-N,N-dimethylethylamine Maleate. Grade: 98% atom D. CAS No. 1216872-59-1. Molecular formula: C20H17D6ClN2O5. Mole weight: 412.9.
Carbocysteine
Carbocisteine (INN), also called carbocysteine (USAN), is a mucolytic that reduces the viscosity of sputum and so can be used to help relieve the symptoms of chronic obstructive pulmonary disorder (COPD) and bronchiectasis by allowing the sufferer to bring up sputum more easily. Carbocisteine should not be used with antitussives (cough suppressants) or medicines that dry up bronchial secretions. Synonyms: S-Carboxymethyl-L-cysteine; (2R)-2-Amino-3-[(carboxymethyl)thio]propionic Acid; (R)-S-(Carboxymethyl)cysteine; (L)-2-Amino-3-(carboxymethylthio)propionic Acid; 3-[(Carboxymethyl)thio]-L-alanine; AHR 3053; Bronchokod; Carbocisteine; Carbocit; Carbocysteine. Grade: ≥ 99%. CAS No. 638-23-3. Molecular formula: C5H9NO4S. Mole weight: 179.2.
Carbomycin A
It is produced by the strain of Streptomyces halstedii. It is mainly resistant to gram-positive bacteria and is cross-resistant to erythromycin. Uses: Sixteen-membered-ring macrolite antibiotic complex similar to leucomycin and erythromycin, produced by stroptomyces halstedii. Synonyms: CARBOMYCIN; Magnamycin; Magnamycin A; Deltamycin A4; Carbomycin acetate; carbomycin; (12S,13S)-9-Deoxy-12,13-epoxy-12,13-dihydro-9-oxoleucomycin V 3-Acetate 4B-(3-Methylbutanoate); M 4209; NSC 51001; NSC 55924. CAS No. 4564-87-8. Molecular formula: C42H67NO16. Mole weight: 841.98.
Carbonic dichloride, polymer with 4,4-(1-methylethylidene)bisphenol
Carbonic dichloride, polymer with 4,4-(1-methylethylidene)bisphenol. Synonyms: Carbonic dichloride, polymer with 4,4-(1-methylethylidene)bisphenol. CAS No. 25971-63-5. Molecular formula: (C15H16O2·CCl2O)x.
Carcinine
Carcinine, a natural peptide derivative, is a highly selective histamine H3 receptor antagonist. It has antioxidant and anti-saccharification functions and has better stability because it is not recognized by enzymes in the body and loses activity. It can be used to remove skin yellow, lighten skin tone, fight against the invasion of external ultraviolet rays and pollutants and other adverse environment on the skin, prevent skin premature aging, maintain skin young state, can be added to beauty care products, such as emulsion, mask, morning, night cream, eye cream, eye serum, facial essence, muscle base liquid, toner, eye mask, gel and so on. Synonyms: Propanamide, 3-amino-N-[2-(1H-imidazol-5-yl)ethyl]-; 3-Amino-N-[2-(1H-imidazol-4-yl)ethyl]propanamide; Alistin; Decarboxycarnosine; β-Alanylhistamine; Decarboxy Carnosine. Grade: ≥98% by HPLC. CAS No. 56897-53-1. Molecular formula: C8H14N4O. Mole weight: 182.22.
Carcinoembryonic Antigen
Carcinoembryonic antigen (CEA), a substance found on the surface of some cells, is a tumor marker in lung cancer. Synonyms: Tyr-Leu-Ser-Gly-Ala-Asn-Leu-Asn-Leu; L-tyrosyl-L-leucyl-L-serylglycyl-L-alanyl-L-asparaginyl-L-leucyl-L-asparaginyl-L-leucine; Carcinoembryonic Antigen; CEA. Grade: ≥95%. CAS No. 168635-85-6. Molecular formula: C43H69N11O14. Mole weight: 964.07.
Carfecillin sodium
Carfecillin sodium, a phenyl derivative of carbenicillin, is a beta-lactam antibiotic used to treat urinary tract infections. Synonyms: Carbenicillin phenyl sodium; carfecilina sodica; Carfexil; Pencina; Purapen; Carfecillin Sodium Salt; sodium [2S-(2alpha,5alpha,6beta)]-6-[(1,3-dioxo-3-phenoxy-2-phenylpropyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate. Grade: 95%. CAS No. 21649-57-0. Molecular formula: C23H21N2NaO6S. Mole weight: 476.48.
Carglumic Acid
Carglumic Acid is an activator of carbamoyl phosphate synthetase 1 (CPS1). It inhibits cell proliferation of a variety of cancer cell lines with IC50 values ranging from 5 to 7.5 nM. Synonyms: N-Carbamyl-L-glutamic acid; (S)-2-ureidopentanedioic acid; Carbaglu; N-Carbamylglutamate; Ureidoglutaric acid; Carbamino-L-glutamic acid. Grade: 95%. CAS No. 1188-38-1. Molecular formula: C6H10N2O5. Mole weight: 190.15.
Carminomycin
It is produced by the strain of Actinomadura carminata. Intravenous injection of 2 to 4 times of yangerythromycin (1.3-2.25mg) in mice could inhibit the growth of bronchial carcinoma, transplanted gastric cancer, lymphoid leukemia L-1210 and lymphosarcoma, but had poor effect on sarcoma-180 and lymphangiopathy, and had no effect on Eilinite ascites carcinoma. Uses: An antitumor antibiotic. Synonyms: Carubicin; Carminomicin; NSC 180024; KARMINOMYCIN; O-Demethyldaunomycin; (1S,3S)-3-acetyl-3,5,10,12-tetrahydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranoside. Grade: ≥95%. CAS No. 39472-31-6. Molecular formula: C26H27NO10. Mole weight: 513.49.
Carminomycin I
It is produced by the strain of Actinomadura carminata. Carubicin intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair, and RNA and protein synthesis. Synonyms: Karminomitsin; NSC180024; NSC-180024; CMM; Karminomycin; (8S-cis)-Acetyl-10-[(3-amino-2,3,6-trideoxy-a-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-1,6,8,11-tetrahydroxy-5,12-naphthacenedione; Antibiotic R 588A; Demethyldaunomycin; (8S,10S)-8-Acetyl-10-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-1,6,8,11-tetrahydroxy-5,12-naphthacenedione; 5,12-Naphthacenedione, 8-acetyl-10-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-1,6,8,11-tetrahydroxy-, (8S-cis)-; Caminomycin; Carminomicin I; Carubicin. Grade: ≥95%. CAS No. 50935-04-1. Molecular formula: C26H27NO10. Mole weight: 513.49.
Carriomycin
It is produced by the strain of Streptomyces hygroscoppicus T-42082. It has activities against gram-positive bacteria, mycoplasma, yeast and pipeospora rice and other fungi and coccidia, but has no effect on gram-negative bacteria, aspergillus, penicillium and other fungi. CAS No. 65978-43-0. Molecular formula: C47H80O15. Mole weight: 885.13.
CART (55-102) (human)
Cocaine- and amphetamine-regulated transcript (CART) is a neuropeptide protein with potent appetite-suppressing activity. It inhibits normal and starvation-induced feeding and blocks the neuropeptide Y-induced feeding response. Synonyms: H-Val-Pro-Ile-Tyr-Glu-Lys-Lys-Tyr-Gly-Gln-Val-Pro-Met-Cys-Asp-Ala-Gly-Glu-Gln-Cys-Ala-Val-Arg-Lys-Gly-Ala-Arg-Ile-Gly-Lys-Leu-Cys-Asp-Cys-Pro-Arg-Gly-Thr-Ser-Cys-Asn-Ser-Phe-Leu-Leu-Lys-Cys-Leu-OH (Disulfide bridge: Cys14-Cys32, Cys20-Cys40, Cys34-Cys47); L-valyl-L-prolyl-L-isoleucyl-L-tyrosyl-L-alpha-glutamyl-L-lysyl-L-lysyl-L-tyrosyl-glycyl-L-glutaminyl-L-valyl-L-prolyl-L-methionyl-L-cysteinyl-L-alpha-aspartyl-L-alanyl-glycyl-L-alpha-glutamyl-L-glutaminyl-L-cysteinyl-L-alanyl-L-valyl-L-arginyl-L-lysyl-glycyl-L-alanyl-L-arginyl-L-isoleucyl-glycyl-L-lysyl-L-leucyl-L-cysteinyl-L-alpha-aspartyl-L-cysteinyl-L-prolyl-L-arginyl-glycyl-L-threonyl-L-seryl-L-cysteinyl-L-asparagyl-L-seryl-L-phenylalanyl-L-leucyl-L-leucyl-L-lysyl-L-cysteinyl-L-leucine (14->32),(20->40),(34->47)-tris(disulfide). Grade: ≥95%. CAS No. 214050-22-3. Molecular formula: C225H365N65O65S7. Mole weight: 5245.18.
CART (55-102) (rat)
Cocaine- and amphetamine-regulated transcript (CART) is a neuropeptide protein with potent appetite-suppressing activity. It inhibits normal and starvation-induced feeding and blocks the neuropeptide Y-induced feeding response. Uses: Appetite suppressant. Synonyms: H-Ile-Pro-Ile-Tyr-Glu-Lys-Lys-Tyr-Gly-Gln-Val-Pro-Met-Cys-Asp-Ala-Gly-Glu-Gln-Cys-Ala-Val-Arg-Lys-Gly-Ala-Arg-Ile-Gly-Lys-Leu-Cys-Asp-Cys-Pro-Arg-Gly-Thr-Ser-Cys-Asn-Ser-Phe-Leu-Leu-Lys-Cys-Leu-OH (Disulfide bridge: Cys14-Cys32, Cys20-Cys40, Cys34-Cys37); L-isoleucyl-L-prolyl-L-isoleucyl-L-tyrosyl-L-alpha-glutamyl-L-lysyl-L-lysyl-L-tyrosyl-glycyl-L-glutaminyl-L-valyl-L-prolyl-L-methionyl-L-cysteinyl-L-alpha-aspartyl-L-alanyl-glycyl-L-alpha-glutamyl-L-glutaminyl-L-cysteinyl-L-alanyl-L-valyl-L-arginyl-L-lysyl-glycyl-L-alanyl-L-arginyl-L-isoleucyl-glycyl-L-lysyl-L-leucyl-L-cysteinyl-L-alpha-aspartyl-L-cysteinyl-L-prolyl-L-arginyl-glycyl-L-threonyl-L-seryl-L-cysteinyl-L-asparagyl-L-seryl-L-phenylalanyl-L-leucyl-L-leucyl-L-lysyl-L-cysteinyl-L-leucine (14->32),(20->40),(34->47)-tris(disulfide). Grade: ≥95%. CAS No. 209615-79-2. Molecular formula: C226H367N65O65S7. Mole weight: 5259.21.
CART (61-102) (human, rat)
CART (61-102) (human, rat) is a peptide derived from the Cocaine- and Amphetamine-Regulated Transcript (CART) protein, used in the research of metabolic disorders, obesity and their associated afflictions. Synonyms: CART (48-89) (human); H-Lys-Tyr-Gly-Gln-Val-Pro-Met-Cys-Asp-Ala-Gly-Glu-Gln-Cys-Ala-Val-Arg-Lys-Gly-Ala-Arg-Ile-Gly-Lys-Leu-Cys-Asp-Cys-Pro-Arg-Gly-Thr-Ser-Cys-Asn-Ser-Phe-Leu-Leu-Lys-Cys-Leu-OH (Disulfide bridge: Cys8-Cys26, Cys14-Cys34, Cys28-Cys41); Cocaine- and amphetamine-regulated transcript fragment 61-102. Grade: 95%. CAS No. 209615-75-8. Molecular formula: C189H310N58O56S7. Mole weight: 4515.36.
CART (62-76) (rat, human)
Cocaine- and amphetamine-regulated transcript (CART) is a neuropeptide protein with potent appetite-suppressing activity. It inhibits normal and starvation-induced feeding and blocks the neuropeptide Y-induced feeding response. Synonyms: H-Tyr-Gly-Gln-Val-Pro-Met-Cys-Asp-Ala-Gly-Glu-Gln-Cys-Ala-Val-OH; L-tyrosyl-glycyl-L-glutaminyl-L-valyl-L-prolyl-L-methionyl-L-cysteinyl-L-alpha-aspartyl-L-alanyl-glycyl-L-alpha-glutamyl-L-glutaminyl-L-cysteinyl-L-alanyl-L-valine; Cocaine and amphetamine-regulated transcript (62-76) (rat, human). Grade: ≥90%. CAS No. 210978-19-1. Molecular formula: C64H99N17O23S3. Mole weight: 1570.77.
Carumonam
It is produced by the strain of Monobactams. As well as Azthreonam, it has excellent curative effect on aerobic gram-negative bacteria (including Pseudomonas aeruginosa) infection, but no effect on gram-positive bacteria and anaerobic bacteria. Synonyms: Carumonamum; AMA 1080; (Z)-Carumonam; 2-[(Z)-[1-(2-amino-1,3-thiazol-4-yl)-2-[[(2S,3S)-2-(carbamoyloxymethyl)-4-oxo-1-sulfoazetidin-3-yl]amino]-2-oxoethylidene]amino]oxyacetic acid; CRMN; CARUMONAM. Grade: 95%. CAS No. 87638-04-8. Molecular formula: C12H14N6O10S2. Mole weight: 466.40.
(±)-Carvedilol-[d4] (ethyl-[d4])
One of the isotopic labelled form of (±)-Carvedilol which is a β-adrenergic blocker and could be used as an antihypertensive agent. Synonyms: (±)-1-(9H-Carbazol-4-yloxy)-3-[[2-(2-methoxyphenoxy)ethyl]amino]-2-propanol. Grade: 95% by HPLC; 98% atom D. CAS No. 1133705-56-2. Molecular formula: C24H22D4N2O4. Mole weight: 410.50.
Caspase-9 Inhibitor III
Caspase-9 Inhibitor III is a potent and irreversible inhibitor of caspase-9 with cardioprotective effects. Caspase inhibitors play an important role in investigating biological processes. Caspase-9 can reduce infarct size, lactate dehydrogenase (LDH) and creatine kinase (CK) release, and DNA smearing induced by ischemia and reperfusion in isolated rat hearts. The caspase family of proteins function as key components of the apoptotic machinery and act to destroy specific target proteins which are critical to cellular longevity. Synonyms: Ac-LEHD-CMK. Grade: 98%. CAS No. 403848-57-7. Molecular formula: C24H35ClN6O9. Mole weight: 587.02.
Caspofungin acetate
Caspofungin acetate is the first in a new class of antifungals that inhibits the synthesis of beta (1, 3)-d-glucan, an essential component of the cell wall of filamentous fungi. Synonyms: MK-0991; MK 0991; MK0991; caspofungin diacetate; Cancidas; L 743872; L 743873; 1-[(4R,5S)-5-[(2-Aminoethyl)amino]-N2-[(10R,12S)-10,12-dimethyl-1-oxotetradecyl]-4-hydroxy-L-ornithine]-5-[(3R)-3-hydroxy-L-ornithine]pneumocandin B0 Diacetate; 1-[(4R,5S)-5-[(2-Aminoethyl)amino]-N2-[(10R,12S)-10,12-dimethyl-1-oxotetradecyl]-4-hydroxy-L-ornithine]-5-(threo-3-hydroxy-L-ornithine)pneumocandin B0 Diacetate. Grade: 98%. CAS No. 179463-17-3. Molecular formula: C56H96N10O19. Mole weight: 1213.42.
(±)-Catechin-[13C3]
(±)-Catechin-[13C3], is the labelled analogue of Catechin. Catechin is a flavan-3-ol, a type of natural phenol and antioxidant. Synonyms: (+/-)-Catechin-2,3,4-13C3. Grade: 98% by CP; 99% atom 13C. CAS No. 1261254-33-4. Molecular formula: C12[13C]3H14O6. Mole weight: 293.25.
Catestatin
Catestatin, a peptide compound, has been found to be a non-competitive nicotinic cholinergic antagonist. Synonyms: Chromogranin A344-364. Grade: >98%. CAS No. 142211-96-9. Molecular formula: C107H173N37O26S. Mole weight: 2425.84.
Catestatin (human)
Catestatin, an inhibitory peptide of catecholamine release, corresponds to human chromogranin A (CHGA) 370-390. Reduced catestatin expression may increase the risk of hypertension. In Chga-/- mice rescue of elevated blood pressure to normalcy was achieved by exogenous substitution of catestatin or transgenic expression of human CHGA. Synonyms: H-Ser-Ser-Met-Lys-Leu-Ser-Phe-Arg-Ala-Arg-Ala-Tyr-Gly-Phe-Arg-Gly-Pro-Gly-Pro-Gln-Leu-OH; L-seryl-L-seryl-L-methionyl-L-lysyl-L-leucyl-L-seryl-L-phenylalanyl-L-arginyl-L-alanyl-L-arginyl-L-alanyl-L-tyrosyl-glycyl-L-phenylalanyl-L-arginyl-glycyl-L-prolyl-glycyl-L-prolyl-L-glutaminyl-L-leucine. Grade: ≥95%. CAS No. 197151-46-5. Molecular formula: C104H164N32O27S. Mole weight: 2326.71.
Cathepsin L Inhibitor
Cathepsin L inhibitor is a potent inhibitor of cathepsin L with IC50 of 0.85 nM. It is trypanocidal with an ED50 value of 45 nM against T. brucei that is well below the ED50 value of 21,500 nM for human HL-60 cells. In vivo, cathepsin L inhibitor (2.5-10 mg/kg) inhibits bone loss in a mouse model of osteoporosis in a dose-dependent manner. Cathepsin L inhibitor can also completely suppress osteoclastic pit formation on femur slices isolated from bovine cortical bone. Synonyms: Z-FY-CHO; Z-Phe-Tyr-aldehyde; SB 412515; N-(benzyloxycarbonyl)-phenylalanyl-l-tyrosinal. Grade: ≥95%. CAS No. 167498-29-5. Molecular formula: C26H26N2O5. Mole weight: 446.49.
CCK Octapeptide (non-sulfated)
Cholecystokinin (CCK) is a neuropeptide and gut hormone that regulates pancreatic enzyme secretion and gastrointestinal motility, and acts as a satiety signal. CCK Octapeptide (non-sulfated) is the non-sulfated form of the C-terminal octapeptide of CCK. Synonyms: CCK-8 (desulfated); Cholecystokinin (CCK) (26-33); 2-desulfo-cholecystokinin-8 (swine). Grade: 98%. CAS No. 25679-24-7. Molecular formula: C49H62N10O13S2. Mole weight: 1063.
CDK2
CDK2, a member of the eukaryotic S/T protein kinase family, catalyzes the phosphoryl transfer of ATP γ-phosphate to serine or threonine hydroxyl (denoted as S0/T0) in a protein substrate. Activity of CDK2 is maximal during S phase and G2; activated by interaction with cyclin E during the early stages of DNA synthesis to permit G1-S transition, and subsequently activated by cyclin A2 (cyclin A1 in germ cells) during the late stages of DNA replication to drive the transition from S phase to mitosis, the G2 phase. Synonyms: Cell division protein kinase 2; kinase Cdk2; p33 protein kinase; Anti-Gastric receptor I; Anti-H2R; His-His-Ala-Ser-Pro-Arg-Lys; L-histidyl-L-histidyl-L-alanyl-L-seryl-L-prolyl-L-arginyl-L-lysine. Grade: ≥95%. CAS No. 255064-79-0. Molecular formula: C35H57N15O9. Mole weight: 831.92.
CEF20
CEF20 is the HLA-A*0201-restricted epitope from cytomegalovirus pp65 (495-503). Synonyms: Asn-Leu-Val-Pro-Met-Val-Ala-Thr-Val; L-asparagyl-L-leucyl-L-valyl-L-prolyl-L-methionyl-L-valyl-L-alanyl-L-threonyl-L-valine; Human CMV pp65 (495-503); CEF20, Cytomegalovirus. Grade: ≥95%. CAS No. 153045-21-7. Molecular formula: C42H74N10O12S. Mole weight: 943.16.
CEF3
CEF3 (SIIPSGPLK) corresponds to aa 13-21 of the influenza A virus M1 protein, and was first described in the yeast Saccharomyces cerevisiae and has subsequently been identified in a wide range of fungal species including Candida albicans and Schizosaccharomyces pombe. The matrix (M1) protein of influenza A virus is a multifunctional protein that plays essential structural and functional roles in the virus life cycle. Synonyms: Influenza Virus M1 (13-21); Ser-Ile-Ile-Pro-Ser-Gly-Pro-Leu-Lys; L-seryl-L-isoleucyl-L-isoleucyl-L-prolyl-L-seryl-glycyl-L-prolyl-L-leucyl-L-lysine. Grade: ≥95%. CAS No. 199727-62-3. Molecular formula: C42H74N10O12. Mole weight: 911.09.