BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Cilengitide | Cilengitide is a cyclic Arg-Gly-Asp peptide with potential antineoplastic activity. Cilengitide binds to and inhibits the activities of the alpha(V)beta(3) and alpha(V)beta(5) integrins, thereby inhibiting endothelial cell-cell interactions, endothelial cell-matrix interactions, and angiogenesis. It is being studied for the treatment of glioblastoma. Synonyms: 2-[(2S,5R,8S,11S)-5-benzyl-11-[3-(diaminomethylideneamino)propyl]-7-methyl-3,6,9,12,15-pentaoxo-8-propan-2-yl-1,4,7,10,13-pentazacyclopentadec-2-yl]acetic acid. Grade: ≥98%. CAS No. 188968-51-6. Molecular formula: C27H40N8O7. Mole weight: 588.65. |  |
| Cilengitide TFA salt | Cilengitide TFA salt, is a cyclic Arg-Gly-Asp acid pentapeptide that induces anoikis in angiogenic blood vessels and brain tumor, selectively and potently blocks the ligation of theαvβ3 andαvβ5 integrins to provisional matrix proteins such as vitronectin, fibronectin, fibrinogen, von Willebrand factor, osteopontin, and others. Synonyms: Cilengitide trifluoroacetate. Grade: >98%. CAS No. 199807-35-7. Molecular formula: C29H41F3N8O9. Mole weight: 702.68. | |
| Cinerubin B | It is produced by the strain of Streptomyces cinereoruber var. fructo fermentans. Cinerubin B has anti-gram-positive bacteria, mycobacterium, fungis and amoeba activity, and has strong effect on mouse adenocarcinoma E0771. Synonyms: Cinerubine B; Tavromycetin III; Antibiotic MA 144B2; NSC 18335. CAS No. 35906-51-5. Molecular formula: C42H51NO16. Mole weight: 825.85. | |
| Cinerubin R | It is produced by the strain of Streptomyces eurythermuss H17515MY2. Cinerubin R has anti-gram-positive bacteria and inhibition of tumor cell activity, and its inhibition effect on multidrug resistant (MDR) cells is the same as that on protocells. Synonyms: 4''-Aculosyl-4'-rhodinosyl-7-rhodosaminyl-epsilon-pyrromycinone; DTXSID50933177. CAS No. 147657-35-0. Molecular formula: C42H51NO15. Mole weight: 809.85. | |
| Cinnamycin | It is an antibiotic produced by several species of streptoverticillium. It is a potent indirect inhibitor of phospholipase A2 by specifically sequestering phosphatidylethanolamine (PE). It has antiviral activity against herpes simplex virus type 1 KOS strain infection in Vero cells. It is also an immunopotentiator. Synonyms: Lanthiopeptin; Ro 09-0198; NSC 71936; Antibiotic NSC-71936; Antibiotic Ro 09-0198; L-cysteinyl-L-arginyl-L-glutaminyl-D-cysteinyl-L-cysteinyl-3-aminoalanyl-L-phenylalanylglycyl-L-prolyl-L-phenylalanyl-(2S,3S)-2-amino-3-mercaptobutanoyl-L-phenylalanyl-L-valyl-L-cysteinyl-(3R)-3-hydroxy-L-a-aspartylglycyl-L-asparaginyl-(2S,3S)-2-amino-3-mercaptobutanoyl-L-lysine, cyclic (1→18), (4→14), (5→11)-tris(thioether), cyclic (6→19)-imine. Grade: >98% by HPLC. CAS No. 110655-58-8. Molecular formula: C89H125N25O25S3. Mole weight: 2041.29. | |
| Ciprofloxacin | Ciprofloxacin is a fluoroquinolone antibiotic, shows broad and potent antibacterial activity, with MIC90 of 0.024-6 μM. It is active against a variety of Gram-positive and Gram-negative bacteria in vitro, including S. aureus, L. monocytogenes, P. aeruginosa, Legionella, N. gonorrhoeae and H. pylori. Synonyms: 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic Acid; Bay q 3939; Ciflafin; Ciprine; Cipro IV; Ciprofloxacillin; Ciprobay; Fimoflox; Ipiflox; Probiox. Grade: >98%. CAS No. 85721-33-1. Molecular formula: C17H18FN3O3. Mole weight: 331.34. | |
| CiproFloxacin hydrochloride monohydrate | A second generation fluoroquinolone antibiotic. Synonyms: 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic Acid Hydrochloride Monohydrate; Bay Q3939 Hydrochloride Monohydrate. Grade: ≥98.0%. CAS No. 86393-32-0. Molecular formula: C17H18FN3O3.HCl.H2O. Mole weight: 385.82. | |
| Cispentacin | Cispentacin is produced by the strain of Streptomyces setonii and Bacillus cereus. It has anti-candida and other fungi activity, and has no toxicity at 1g/kg. Synonyms: 2-aminocyclopentane-1-carboxylic acid; cis-2-Ac5c; cispentacin, (cis)-isomer. Grade: ≥ 95%. CAS No. 122672-46-2. Molecular formula: C6H11NO2. Mole weight: 129.16. | |
| Cisplatin | Cisplatin induces cytotoxicity by interaction with DNA to form DNA adducts which activate several signal transduction pathways, including Erk, p53, p73, and MAPK, which culminates in the activation of apoptosis. It is used in several types of cancer. Uses: Antineoplastic agent. Synonyms: (SP-4-2)-diamminedichloro-platinum. Grade: >98%. CAS No. 15663-27-1. Molecular formula: Cl2H6N2Pt. Mole weight: 300.05. | |
| (-)-Citrinin-[13C,d2] | (-)-Citrinin-[13C,d2] is the labelled analogue of (-)-Citrinin, which is produced by the strain of Penicillum citrinum. Synonyms: (-)-Citrinin-13C,D2; (3R,4S)-4,6-Dihydro-8-hydroxy-3,4,5-trimethyl-6-oxo-3H-2-benzopyran-7-carboxylic Acid-13C,d2; (3R-trans)-4,6-Dihydro-8-hydroxy-3,4,5-trimethyl-6-oxo-3H-2-benzopyran-7-carboxylic Acid-13C,d2; Citrinin-13C,d2; NSC 186-13C,d2. Grade: >95%. CAS No. 1329611-85-9. Molecular formula: C12[13C]H12D2O5. Mole weight: 253.25. | |
| Citromycetin | Citromycetin is produced by the strain of Citromyces sp. and Penicillum frequentans. Independently isolated and named from a number of different fungal species during the 1930s to 1950s; active against gram positive bacteria. Synonyms: 4H,5H-Pyrano(3,2-c)(1)benzopyran-10-carboxylic acid, 8,9-dihydroxy-2-methyl-4-oxo-. Grade: >95% by HPLC. CAS No. 478-60-4. Molecular formula: C14H10O7. Mole weight: 290.22. | |
| Cladospirone bisepoxide | It is produced by the strain of Cladosporium sp. F-24707. Cladospirone bisepoxide has the ability to inhibit yeast, filamentous fungi, and bacterial, and can inhibit germination of Lepidium sativum at low concentrations. Synonyms: Cladospirone bisepoxide. CAS No. 155866-40-3. Molecular formula: C20H14O7. Mole weight: 366.32. | |
| Cladosporin | It is produced by the strain of Cladosporium cladosporiodes. Cladosporin has the activity of weak resistance to gram-positive bacteria, tinea trichoderma, microspora, potato filaria and other fungi. Synonyms: 3,4-Dihydro-6,8-dihydroxy-3-(6-methyltetrahydropyran-2-ylmethyl)isocoumarin; Asperentin; (R)-6,8-Dihydroxy-3-(((2R,6S)-6-methyltetrahydro-2H-pyran-2-yl)methyl)isochroman-1-one; 1H-2-Benzopyran-1-one, 3,4-dihydro-6,8-dihydroxy-3-[[(2R,6S)-tetrahydro-6-methyl-2H-pyran-2-yl]methyl]-, (3R)-; (3R)-3,4-Dihydro-6,8-dihydroxy-3-[[(2R,6S)-tetrahydro-6-methyl-2H-pyran-2-yl]methyl]-1H-2-benzopyran-1-one; 1H-2-Benzopyran-1-one, 3,4-dihydro-6,8-dihydroxy-3-[(tetrahydro-6-methyl-2H-pyran-2-yl)methyl]-, [2R-[2α(R*),6β]]-. Grade: ≥95% by HPLC. CAS No. 35818-31-6. Molecular formula: C16H20O5. Mole weight: 292.33. | |
| Clarithromycin | It is produced by the strain of erythromycin. Clarithromycin, a CYP3A4 inhibitor, is a macrolide antibiotic used to treat pharyngitis, tonsillitis, acute maxillary sinusitis, acute bacterial exacerbation of chronic bronchitis, pneumonia, skin and skin structure infections. It prevents bacteria from growing by interfering with their protein synthesis and binds to the subunit 50S of the bacterial ribosome and thus inhibits the translation of peptides. It has similar antimicrobial spectrum as erythromycin, but is more effective against certain Gram-negative bacteria, particularly Legionella pneumophila. It also has bactericidal effect on certain strains, such as Haemophilus influenzae, Streptococcus pneumoniae and Neisseria gonorrhoeae. Uses: Anti-bacterial agents. Synonyms: Biaxin; 6-O-Methylerythromycin; Klaricid; Abbott-56268; 6-O-Methylerythromycin A; A 56268; Abbott 56268; Antibiotic A 56268; Antibiotic TE 31; Clamicin; Claric; Claridar; Claris; Claritek; Clarith; Clarithro; Clathromycin; Crixan; CRIXAN OD; Fascar; Fromilid; Kelamycin; Klabax; Klacid; Klaribac; Klarimix; Klarithran MR; Macladin; Naxy; TE 031; Veclam; Zeclar. Grade: >98%. CAS No. 81103-11-9. Molecular formula: C38H69NO13. Mole weight: 747.95. | |
| Clarithromycin related compound I | An impurity found in the macrolide antibiotic, Clarithromycin. Synonyms: De(cladinosyl) Clarithromycin; 3-O-De(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)-6-O-methylerythromycin; 5-O-Desosaminyl-6-O-methylerythronolide A; 3-O-Decladinosyl-6-O-methylerythronolide A; Clarithromycin EP Impurity I. Grade: ≥90.0%. CAS No. 118058-74-5. Molecular formula: C30H55NO10. Mole weight: 589.77. | |
| Clavulanate Lithium | A beta-lactamase inhibitor. It can irreversibly inactivate beta-lactamase enzymes of beta-lactam resistant microbes preventing them from breaking down beta-lactam antibiotics. Synonyms: (2R,5R,Z)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylate Lithium; Clavulanic acid, lithium salt. Grade: ≥98%. CAS No. 61177-44-4. Molecular formula: C8H8LiNO5. Mole weight: 205.09. | |
| Clavulanate Potassium (1:1 mixture with silicon dioxide) | Clavulanate Potassium is a semi-synthetic beta-lactamase inhibitor isolated from streptomyces. It contains a beta-lactam ring and binds strongly to beta-lactamase at or near its active site. It is used in conjunction with beta-lactamase susceptible penicillins to treat infections caused by beta-lactamase producing organisms. It is commonly combined with amoxicillin or ticarcillin to increase its effectiveness. Uses: Beta-lactamase inhibitors. Synonyms: Amonate; MM-14151; MM14151. CAS No. 61177-45-5. Molecular formula: C8H8KNO5. Mole weight: 237.25. | |
| Clavulanate-TEG-Biotin | Clavulanate-TEG-Biotin. Synonyms: 13-oxo-17-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-3,6,9,12-tetraoxaheptadecyl (2R,5R,Z)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylate. Molecular formula: C26H39N3O11S. Mole weight: 601.7. | |
| Clavulanic acid | It is produced by the strain of Streptomyces clavuligerus. Clavulanic acid has a strong inhibition of β-lactamase activity, almost no antibacterial effect. Synonyms: Acido clavulanico; Acide clavulanique; acidum clavulanicum; Clavulansaeure. Grade: 95%. CAS No. 58001-44-8. Molecular formula: C8H9NO5. Mole weight: 199.16. | |
| Clazamycin B | It is produced by the strain of Streptomyces No. NF990-BF4. Clazamycin A has weak activity against gram-positive bacteria, gram-negative bacteria and L1210 cell. Synonyms: Antibiotic 354; (2S-cis)-2-Chloro-5-imino-2,3-dihydro-1H-pyrrolizin-7a(5H)-ol. CAS No. 71774-49-7. Molecular formula: C7H9ClN2O. Mole weight: 172.61. | |
| Clindamycin | Clindamycin is produced by the strain of semi-synthetic lincomycin. The antibacterial spectrum of chloralincomycin is the same as that of Lincomycin, but its antibacterial activity is stronger, and its effect on anaerobic bacteria such as fragile Bacteroides is equivalent to 3-4 times of that of Lincomycin. It can be injected or administered orally, and oral absorption is obviously superior to lincomycin. Synonyms: Clindamycin phosphate EP Impurity E; Dalacine; Chlolincocin; Dalacin C; 7-Chlorolincomycin. Grade: >98%. CAS No. 18323-44-9. Molecular formula: C18H33ClN2O5S. Mole weight: 424.98. | |
| Clindamycin 2-Phosphate | Clindamycin Phosphate is a lincosamide antibiotic for Plasmodium falciparum with IC50 of 12 nM. It is usually used to treat infections with anaerobic bacteria, but can also be used to treat protozoal diseases, such as malaria. It is a common drug used to treat topical acne and can be effective against some methicillin-resistant Staphylococcus aureus (MRSA) infections. An impurity of Clindamycin. Synonyms: Methyl 7-Chloro-6,7,8-trideoxy-6-trans-(1-methyl-4-propyl-L-2-pyrrolidine-carboxamido)-1-thio-L-threo-α-D-galactooctopyranoside 2-(Dihydrogen Phosphate); 7(S)-Chloro-7-deoxylincomycin 2-Phosphate; Cleocin T; Cleocin Phosphate; Clinadac; Clindagel; Clindesse; Clindets; Dalacin P; Dalacin T; NSC 618653. Grade: Content:≥ 758 μg/mg. CAS No. 24729-96-2. Molecular formula: C18H34ClN2O8PS. Mole weight: 504.96. | |
| Clindamycin hydrochloride monohydrate | Clindamycin is an antibiotic in the lincosamide class which binds the bacterial 50S ribosomal subunit and interferes with protein synthesis. CAS No. 58207-19-5. Molecular formula: C18H36Cl2N2O6S. Mole weight: 479.46. | |
| Clotrimazole | Clotrimazole is a synthetic, antifungal and broad-spectrum derivate of imidazole. It is an antifungal medication commonly used in the treatment of fungal infections. Synonyms: Lotrimin; Canesten; Mycelex; Clotrimazol; Mycosporin; Empecid; 1H-Imidazole, 1-[(2-chlorophenyl)diphenylmethyl]-; 1-[(2-Chlorophenyl)diphenylmethyl]-1H-imidazole; Imidazole, 1-(o-chloro-α,α-diphenylbenzyl)-; 1-(o-Chlorophenyldiphenylmethyl)imidazole; 1-(o-Chlorotrityl)imidazole; Agisten; Canifug; Femcare; Locasten; Monobaycuten; NSC 257473; Pedisafe; Plimycol; Rimazole; Tibatin; Trimysten; Veltrim. Grade: >98%. CAS No. 23593-75-1. Molecular formula: C22H17ClN2. Mole weight: 344.84. | |
| Cloxacillin | It is produced by the strain of semisynthetic isoxazole penicillin. Cloxacillin is a semisynthetic beta-lactamase resistant penicillin antibiotic with antibacterial activity. It is a chlorinated derivative of oxacillin and is an antibiotic useful for the treatment of a number of bacterial infections. It binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall, thus preventing the cross-linkage of peptidoglycans, which leads to an interruption of the bacterial cell wall and causes bacterial cell lysis. It is used against staphylococci that produce beta-lactamase, due to its large R chain, which does not allow the beta-lactamases to bind. It was discovered and developed by Beecham. Uses: Cloxacillin is an antibiotic useful for the treatment of a number of bacterial infections. Synonyms: Cloxacillinum; Cloxacilina; Syntarpen; Tegopen; (3-(o-Chlorophenyl)-5-methyl-4-isoxazolyl)penicillin. Grade: 98%. CAS No. 61-72-3. Molecular formula: C19H18ClN3O5S. Mole weight: 435.88. | |
| Cloxacillin Sodium Monohydrate | Cloxacillin Sodium Monohydrate is a sodium salt of cloxacillin that is a penicillinase-resistant, acid resistant, semi-synthetic penicillin. Uses: Anti-bacterial agents. Synonyms: Cloxapen. Grade: >98%. CAS No. 7081-44-9. Molecular formula: C19H19ClN3NaO6S. Mole weight: 475.88. | |
| CMD178 TFA | CMD178 (TFA) is a peptide, which consistently reduced the expression of Foxp3 and STAT5 induced by IL-2/sIL-2Rα signaling. Synonyms: H-Arg-Phe-Lys-Phe-Tyr-OBn.TFA; L-arginyl-L-phenylalanyl-L-lysyl-L-phenylalanyl-L-tyrosine benzyl ester trifluoroacetic acid; RFKFY-OBn.TFA; CMD 178 TFA; CMD-178 TFA. Grade: 98%. CAS No. 2703745-81-5. Molecular formula: C46H59N9O7.C2HF3O2. Mole weight: 964.05. | |
| CMP-N-acetylneuraminic acid 9-sp-biotin | CMP-N-acetylneuraminic acid 9-sp-biotin. | |
| c-Myc Peptide | c-Myc Peptide Trifluoroacetate is a synthetic peptide corresponding to the C-terminal amino acids (410-419) of human c-myc protein, and participates in regulation of growth-related gene transcription. Synonyms: H-Glu-Gln-Lys-Leu-Ile-Ser-Glu-Glu-Asp-Leu-OH; L-alpha-glutamyl-L-glutaminyl-L-lysyl-L-leucyl-L-isoleucyl-L-seryl-L-alpha-glutamyl-L-alpha-glutamyl-L-alpha-aspartyl-L-leucine; L-Leucine, L-α-glutamyl-L-glutaminyl-L-lysyl-L-leucyl-L-isoleucyl-L-seryl-L-α-glutamyl-L-α-glutamyl-L-α-aspartyl-; L-Leucine, N-[N-[N-[N-[N-[N-[N-[N2-(N2-L-α-glutamyl-L-glutaminyl)-L-lysyl]-L-leucyl]-L-isoleucyl]-L-seryl]-L-α-glutamyl]-L-α-glutamyl]-L-α-aspartyl]-; L-α-Glutamyl-L-glutaminyl-L-lysyl-L-leucyl-L-isoleucyl-L-seryl-L-α-glutamyl-L-α-glutamyl-L-α-aspartyl-L-leucine; c-Myc epitope tag; c-Myc-tag; cMYC tag (synthetic); Myc peptide; Myc-tag; Neuroblastoma suppressor of tumorigenicity 1 (human clone WO2014/074532-SEQID-317); Transcription factor c-myc (fragment); Transcription factor c-myc (synthetic C-terminal epitope). Grade: ≥95%. CAS No. 145646-22-6. Molecular formula: C51H86N12O21. Mole weight: 1203.30. | |
| Coformycin | Coformycin is a potent inhibitor of adenosine deaminase (ADA) from Streptomyces species. Coformycin possesses anti-tumor and anti-bacterial activity. Synonyms: (R)-3,4,7,8-Tetrahydro-3-beta-D-ribofuranosylimidazo(4,5-d)(1,3)diazepin-8-ol; (8R)-3-beta-D-ribofuranosyl-3,6,7,8-tetrahydroimidazo[4,5-d][1,3]diazepin-8-ol. Grade: 98%. CAS No. 11033-22-0. Molecular formula: C11H16N4O5. Mole weight: 284.27. | |
| COG 133 | COG 1333 is a fragment of ApoE that exhibits anti-inflammatory and neuroprotective effects and could also be an antagonist at α7 nicotinic acetylcholine receptors. Synonyms: COG133; COG-133; Leu-Arg-Val-Arg-Leu-Ala-Ser-His-Leu-Arg-Lys-Leu-Arg-Lys-Arg-Leu-Leu. Grade: 98%. CAS No. 514200-66-9. Molecular formula: C97H181N37O19. Mole weight: 2169.73. | |
| COG 133 acetate | COG 133 acetate is a fragment of ApoE that exhibits anti-inflammatory and neuroprotective effects and could also be an antagonist at α7 nicotinic acetylcholine receptors. Synonyms: Ac-Leu-Arg-Val-Arg-Leu-Ala-Ser-His-Leu-Arg-Lys-Leu-Arg-Lys-Arg-Leu-Leu-NH2.CH3CO2H; N-acetyl-L-leucyl-L-arginyl-L-valyl-L-arginyl-L-leucyl-L-alanyl-L-seryl-L-histidyl-L-leucyl-L-arginyl-L-lysyl-L-leucyl-L-arginyl-L-lysyl-L-arginyl-L-leucyl-L-leucinamide acetic acid; L-Leucinamide, N-acetyl-L-leucyl-L-arginyl-L-valyl-L-arginyl-L-leucyl-L-alanyl-L-seryl-L-histidyl-L-leucyl-L-arginyl-L-lysyl-L-leucyl-L-arginyl-L-lysyl-L-arginyl-L-leucyl-, acetate (1:1). Grade: ≥95%. CAS No. 2763583-75-9. Molecular formula: C99H185N37O21. Mole weight: 2229.76. | |
| COG 133 TFA | COG133 is a peptide fragment of ApoE that corresponds to residues 133-149 of the ApoE LDL receptor-binding domain and an antagonist of α7 nicotinic acetylcholine receptors (nAChRs; IC50 = 720 nM). It suppresses TNF-α and nitric oxide (NO) release in BV-2 microglia when used at concentrations ranging from 10 to 50 μM. Synonyms: L-Leucinamide, N-acetyl-L-leucyl-L-arginyl-L-valyl-L-arginyl-L-leucyl-L-alanyl-L-seryl-L-histidyl-L-leucyl-L-arginyl-L-lysyl-L-leucyl-L-arginyl-L-lysyl-L-arginyl-L-leucyl-, 2,2,2-trifluoroacetate (1:1); Ac-Leu-Arg-Val-Arg-Leu-Ala-Ser-His-Leu-Arg-Lys-Leu-Arg-Lys-Arg-Leu-Leu-NH2.TFA; N-acetyl-L-leucyl-L-arginyl-L-valyl-L-arginyl-L-leucyl-L-alanyl-L-seryl-L-histidyl-L-leucyl-L-arginyl-L-lysyl-L-leucyl-L-arginyl-L-lysyl-L-arginyl-L-leucyl-L-leucinamide trifluoroacetic acid. Grade: 98%. CAS No. 2828432-37-5. Molecular formula: C99H182F3N37O21. Mole weight: 2283.78. | |
| Colchicine | Colchicine, a toxic plant-derived alkaloid extracted from plants of the genus Colchicum, inhibits microtubule polymerization (IC50 = 3.2 μM). It inhibits the growth of MCF-7 human breast carcinoma cells and has anti-inflammatory activity. Colchicine can lower body temperature, inhibit the respiratory center, enhance the effect of sympathomimetic drugs, constrict blood vessels, and raise blood pressure. Synonyms: (S)-N-(5,6,7,9-Tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl)acetamide; (-)-Colchicine; Colchineos; Colchisol; Colcin; Colsaloid; Condylon; NSC 757. Grade: >98%. CAS No. 64-86-8. Molecular formula: C22H25NO6. Mole weight: 399.44. | |
| Colistin | It is produced by the strain of Bacillus polymyxa var. colistinus and Bac. colistinum Koyama 70-B. It has good anti-gram-negative bacterial activity, but has poor effect on Pseudomonas aeruginosa and Proteus aeruginosa. Colistin, also known as polymyxin E, is an antibiotic medication used as a last-resort treatment for multidrug-resistant Gram negative infections including pneumonia. Synonyms: Polymyxin E; Colobreathe; Promixin; Colimycin M; Belcomycin; Colymycin; Torazin; N-[(1S)-3-amino-1-[[(1S,2R)-1-[[(1S)-3-amino-1-[[(3S,6S,9S,12S,15R,18S,21S)-6,9,18-tris(2-aminoethyl)-3-[(1R)-1-hydroxyethyl]-12,15-diisobutyl-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptazacyclotricos-21-yl]carbamoyl]propyl]carbamoyl]-2-hydroxy-propyl]carbamoyl]propyl]-5-methyl-heptanamide. Grade: >95% by HPLC. CAS No. 1066-17-7. Molecular formula: C52H98N16O13. Mole weight: 1155.43. | |
| Colistin A | Colistin A is an antibiotic produced by certain strains of the bacteria Paenibacillus polymyxa. Colistin is a polymyxin antibiotic and can be used to combat infections caused by problematic gram-negative bacteria. Synonyms: Polymixin E1. Grade: ≥ 95%. CAS No. 7722-44-3. Molecular formula: C53H100N16O13. Mole weight: 1169.48. | |
| Colistin sodium methanesulfonate | A unique sparingly soluble cyclic polypeptide antibiotic known as a polymyxin. It has a bactericidal effect on bacteria by targeting the cell membrane and modifying its permeability. CAS No. 8068-28-8. Molecular formula: C58H105N16Na5O28S5. Mole weight: 1749.8. | |
| Colistin sulfate | Colistin sulfate is a polypeptide antibiotic containing greater than 30 components, with colistin A and colistin B as the major components. It inhibits gram-negative bacteria by binding to lipopolysaccharides and phospholipids in the outer cell membrane of gram-negative bacteria. Colistin was originally isolated from B. polymyxa. Synonyms: Polymyxin E Complex; Colistin sulfate salt (2:5); Belcomycine; Colomycin. Grade: ≥95%. CAS No. 1264-72-8. Molecular formula: Colistin A: C53H100N16O13; Colistin B: C52H98N16O13. Mole weight: Colistin A: 1169.46; Colistin B: 1155.43. | |
| Colivelin | Colivelin, a neuroprotective peptide and activator of STAT3, is able to suppress neuronal death and protect neurons against the neurotoxic effects of amyloid β-peptide (1-43) at a concentration of 100 fM in vitro. Uses: Implicated in alzheimer's disease. Synonyms: Ser-Ala-Leu-Leu-Arg-Ser-Ile-Pro-Ala-Pro-Ala-Gly-Ala-Ser-Arg-Leu-Leu-Leu-Leu-Thr-Gly-Glu-Ile-Asp-Leu-Pro; L-seryl-L-alanyl-L-leucyl-L-leucyl-L-arginyl-L-seryl-L-isoleucyl-L-prolyl-L-alanyl-L-prolyl-L-alanyl-glycyl-L-alanyl-L-seryl-L-arginyl-L-leucyl-L-leucyl-L-leucyl-L-leucyl-L-threonyl-glycyl-L-alpha-glutamyl-L-isoleucyl-L-alpha-aspartyl-L-leucyl-L-proline. Grade: ≥95%. CAS No. 867021-83-8. Molecular formula: C119H206N32O35. Mole weight: 2645.13. | |
| Colominic acid sodium salt | Colominic acid sodium salt is an exquisite compound, used for studying bacterial infections evoked by Streptococcus pneumoniae and Haemophilus influenzae. Unveiling its remarkable antimicrobial activity, this compound emerges as a quintessential constituent within pharmaceutical formulations, including antibiotics and vaccines. Synonyms: Poly[2,8-(N-acetylneuraminic acid sodium salt)]; Sodium colominate; Polysialic Acid Sodium Salt. CAS No. 70431-34-4. Molecular formula: (C11H16NNaO8)n. | |
| Compstatin | Compstatinis, a 13-residue cyclic peptide, is a potent inhibitor of the complement system (IC50= 12 μM) and binds to complement component C3. Synonyms: H-Ile-Cys(1)-Val-Val-Gln-Asp-Trp-Gly-His-His-Arg-Cys(1)-Thr-NH2; L-isoleucyl-L-cysteinyl-L-valyl-L-valyl-L-glutaminyl-L-alpha-aspartyl-L-tryptophyl-glycyl-L-histidyl-L-histidyl-L-arginyl-L-cysteinyl-L-threoninamide (2->12)-disulfide; 2-[(4R,7S,10S,13S,19S,22S,25S,28S,31S,34R)-4-[[(2S,3R)-1-amino-3-hydroxy-1-oxobutan-2-yl]carbamoyl]-34-[[(2S,3S)-2-amino-3-methylpentanoyl]amino]-25-(3-amino-3-oxopropyl)-7-[3-(diaminomethylideneamino)propyl]-10,13-bis(1H-imidazol-5-ylmethyl)-19-(1H-indol-3-ylmethyl)-6,9,12,15,18,21,24,27,30,33-decaoxo-28,31-di(propan-2-yl)-1,2-dithia-5,8,11,14,17,20,23,26,29,32-decazacyclopentatriacont-22-yl]acetic acid. Grade: 98%. CAS No. 206645-99-0. Molecular formula: C66H99N23O17S2. Mole weight: 1550.77. | |
| Compstatin control peptide | Compstatin control peptide is a kind of control peptide for compstatin. It is a complement inhibitor. Grade: >98%. CAS No. 301544-78-5. Molecular formula: C66H101N23O17. Mole weight: 1488.67. | |
| Conantokin-R | Conantokin-R is a potent and non-competitive NMDA receptor antagonist with IC50 value of 93 nM. It also has NR2 subunit selectivity. It inhibits inward currents evoked by NMDA in central nervous system neurons. It shows broad antiparkinsonian and anticonvulsant activity in vivo. Synonyms: Conantokin R; 202925-60-8; conantokin-RAKOS024457444; CID 90488802. Grade: >98%. CAS No. 202925-60-8. Molecular formula: C127H201N35O49S3. Mole weight: 3098.4. | |
| Conantokin-T | Conantokin-T is a non-competitive NMDA receptor antagonist with IC50 value of 0.4 μM. It inhibits Ca2+ influx and glutamate-induced toxicity in central nervous system neurons. It has age-dependent physiological effects. It induces hyperactivity in older mice and a sleep-like state in young mice. Uses: Excitatory amino acid antagonists. Synonyms: Conantokin t. Grade: >98%. CAS No. 127476-26-0. Molecular formula: C110H175N31O45S. Mole weight: 2683.8. | |
| Concanamycin A | It is produced by the strain of Streptomyces diastatochromogenes. It has antifungal, antiviral, immunosuppressive, cytotoxic and other activities, and is a specific inhibitor of V-type ATPase (Ki=0.02 nmol/L), which is an important tool for biochemical research. Synonyms: Folimycin; concanamycin a; Antibiotic X 4357 B; Antibiotic S-45A; X 4357B; (3Z,5E,7R,8R,9S,10S,11R,13E,15E,17S,18R)-18-[(1S,2R,3S)-3-[(2R,4R,5S,6R)-4-[[4-O-(Aminocarbonyl)-2,6-dideoxy-β-D-arabino-hexopyranosyl]oxy]tetrahydro-2-hydroxy-5-methyl-6-(1E)-1-propen-1-yl-2H-pyran-2-yl]-2-hydroxy-1-methylbutyl]-9-ethyl-8,10-dihydroxy-3,17-dimethoxy-5,7,11,13-tetramethyloxacyclooctadeca-3,5,13,15-tetraen-2-one. Grade: 98%. CAS No. 80890-47-7. Molecular formula: C46H75NO14. Mole weight: 866.09. | |
| Concanamycin B | It is produced by the strain of Streptomyces diastatochromogenes. It has antifungal, antiviral, immunosuppressive, cytotoxic and other activities, and is a specific inhibitor of V-type ATPase, which is an important tool for biochemical research. Synonyms: (3Z,5E,7R,8R,9S,10S,11R,13E,15E,17S,18R)-18-[(1S,2R,3S)-3-[(2R,4R,5S,6R)-4-[[4-O-(Aminocarbonyl)-2,6-dideoxy-β-D-arabino-hexopyranosyl]oxy]tetrahydro-2-hydroxy-5-methyl-6-(1E)-1-propenyl-2H-pyran-2-yl]-2-hydroxy-1-methylbutyl]-8,10-dihydroxy-3,17-dimethoxy-5,7,9,11,13-pentamethyloxacyclooctadeca-3,5,13,15-tetraen-2-one; MCH 210; 8-Deethyl-8-methylconcanamycin A. Grade: >95% by HPLC. CAS No. 81552-33-2. Molecular formula: C45H73NO14. Mole weight: 852.06. | |
| Concanamycin C | It is produced by the strain of Streptomyces diastatochromogenes. It has antifungal, antiviral, immunosuppressive, cytotoxic and other activities, and is a specific inhibitor of V-type ATPase, which is an important tool for biochemical research. Synonyms: (3Z,5E,7R,8R,9S,10S,11R,13E,15E,17S,18R)-18-[(1S,2R,3S)-3-[(2R,4R,5S,6R)-4-[(2,6-Dideoxy-β-D-arabino-hexopyranosyl)oxy]tetrahydro-2-hydroxy-5-methyl-6-(1E)-1-propen-1-yl-2H-pyran-2-yl]-2-hydroxy-1-methylbutyl]-9-ethyl-8,10-dihydroxy-3,17-dimethoxy-5,7,11,13-tetramethyloxacyclooctadeca-3,5,13,15-tetraen-2-one; 4'-O-de(aminocarbonyl)-Concanamycin A. Grade: ≥98%. CAS No. 81552-34-3. Molecular formula: C45H74O13. Mole weight: 823.06. | |
| Conglobatin | Conglobatin is produced by the strain of Streptomyces conglobatus. It has a unusual, dimeric, macrolide dilactone structure with pendant oxazole groups. It exhibits an IC50 of 0.63 μg/mL in a NFAT-dependant transcription assay. It has no antifungal, bacterial, protozoan and tumor activity. Synonyms: (-)-Conglobatin; Conglobatin A; FW-04-806. Grade: >98% by HPLC. CAS No. 72263-05-9. Molecular formula: C28H38N2O6. Mole weight: 498.61. | |
| Conopressin G | Conopressin G is a vasotocin-like peptide isolated from the venom of the worm-hunting snail (conus imperialis). Synonyms: Glycinamide, L-cysteinyl-L-phenylalanyl-L-isoleucyl-L-arginyl-L-asparaginyl-L-cysteinyl-L-prolyl-L-lysyl-, cyclic (1→6)-disulfide; Conopressin G (Conus geographus); Conopressin L1; Lysine-conopressin (Erpobdella octoculata); Lysine-conopressin (Lymnaea stagnalis); H-Cys-Phe-Ile-Arg-Asn-Cys-Pro-Lys-Gly-NH2 (Disulfide bridge: Cys1-Cys6); L-cysteinyl-L-phenylalanyl-L-isoleucyl-L-arginyl-L-asparagyl-L-cysteinyl-L-prolyl-L-lysyl-glycinamide (1->6)-disulfide; Lys-Conopressin-G. Grade: 95%. CAS No. 111317-91-0. Molecular formula: C44H71N15O10S2. Mole weight: 1034.26. | |
| Conopressin S acetate | Conopressin S acetate, isolated from Conus striatus, has a high affinity with vasopressin V1b receptor (AVPR1B) with a Ki of 8.3 nM. Synonyms: Con-S acetate; Conopressin A1 acetate; H-Cys-Ile-Ile-Arg-Asn-Cys-Pro-Arg-Gly-NH2.CH3CO2H (Disulfide bridge: Cys1-Cys6); L-cysteinyl-L-isoleucyl-L-isoleucyl-L-arginyl-L-asparagyl-L-cysteinyl-L-prolyl-L-arginyl-glycinamide (1->6)-disulfide acetate. Grade: ≥95%. Molecular formula: C43H77N17O12S2. Mole weight: 1088.32. | |
| Copeptin (human) | Copeptin (CT-ProAVP) initially produces the same amount of (Arg8)-Vasopressin (AVP), which has become a prognostic indicator for a variety of diseases, such as sepsis, community-acquired pneumonia, chronic obstructive pulmonary failure, heart failure, and myocardial infarction. Synonyms: H-Ala-Ser-Asp-Arg-Ser-Asn-Ala-Thr-Gln-Leu-Asp-Gly-Pro-Ala-Gly-Ala-Leu-Leu-Leu-Arg-Leu-Val-Gln-Leu-Ala-Gly-Ala-Pro-Glu-Pro-Phe-Glu-Pro-Ala-Gln-Pro-Asp-Ala-Tyr-OH; L-Alanyl-L-seryl-L-α-aspartyl-L-arginyl-L-seryl-L-asparaginyl-L-alanyl-L-threonyl-L-glutaminyl-L-leucyl-L-α-aspartylglycyl-L-prolyl-L-alanylglycyl-L-alanyl-L-leucyl-L-leucyl-L-leucyl-L-arginyl-L-leucyl-L-valyl-L-glutaminyl-L-leucyl-L-alanylglycyl-L-alanyl-L-prolyl-L-α-glutamyl-L-prolyl-L-phenylalanyl-L-α-glutamyl-L-prolyl-L-alanyl-L-glutaminyl-L-prolyl-L-α-aspartyl-L-alanyl-L-tyrosine; CT-ProAVP. Grade: ≥95%. CAS No. 78362-34-2. Molecular formula: C177H279N49O58. Mole weight: 4021.46. | |
| Cordycepin | It is produced by the strain of Cordyceps militaris and Aspergillus niaulans. Cordycepin can inhibit RNA biosynthesis and has anti-gram-positive and mycobacterium activities. Cordycepin has attracted much attention from scholars in the fields of anti-aging, health care, and new drug development. Uses: Anti-metastatic. Synonyms: 3'-Deoxyadenosine; Cordycepine; 9-Cordyceposidoadenine; 9-(beta-D-3'-Deoxyribofuranosyl)adenine; 9-(3-Deoxy-β-D-ribofuranosyl)adenine; 9-(3-Deoxy-β-D-erythro-pentofuranosyl)-9H-purin-6-amine; NSC 401022; NSC 63984. Grade: ≥ 97%. CAS No. 73-03-0. Molecular formula: C10H13N5O3. Mole weight: 251.24. | |
| Cortistatin 14 (mouse, rat) | Cortistatin-14 is an endogenous neuropeptide expressed in the cortex and hippocampus. Synonyms: Cortistatin-14; H-PRO-CYS-LYS-ASN-PHE-PHE-TRP-LYS-THR-PHE-SER-SER-CYS-LYS-OH; CST-14; CST-14 (RAT). Grade: 98%. CAS No. 186901-48-4. Molecular formula: C81H113N19O19S2. Mole weight: 1721.01. | |
| Cortistatin-17 (human) | Cortistatin-17, a structural analogue of somatostatin, binds to all somatostatin receptor subtypes (SSTR) in a manner similar to rat cortistatin. Its inhibition on the cAMP production of forskolin-stimulated in chinese hamster ovary cells expressing SSTR2-5 are dose-dependent, but slightly less efficient than somatostatin-14. Like rat cortistatin, it affects sleep and wake patterns in rats. It reduces light slow wave sleep (SWS1) and increases deep slow wave sleep (SWS2) in a dose-dependent manner. Administration of the peptide causes a temporary flattening of cortical and hippocampal electroencephalograms. Synonyms: H-Asp-Arg-Met-Pro-Cys-Arg-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Ser-Ser-Cys-Lys-OH (Disulfide bridge: Cys5-Cys16); L-alpha-aspartyl-L-arginyl-L-methionyl-L-prolyl-D-cysteinyl-D-arginyl-L-asparagyl-L-phenylalanyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-D-phenylalanyl-D-seryl-L-seryl-L-cysteinyl-L-lysine (5->16)-disulfide; L-α-Aspartyl-L-arginyl-L-methionyl-N-[(4R,7S,10R,13R,16S,19S,22R,25S,28S,31S,34R. Grade: 95%. CAS No. 189450-19-9. Molecular formula: C96H139N27O24S3. Mole weight: 2151.53. | |
| Cortistatin-29 (rat) | Cortistatin-29 is a neuropeptide that has structurally similarity to somatostatin-28. It is produced by cleavage of preprocortistatin to procortistatin, which is cleaved at dibasic amino acids to form cortistatin-29 and cortistatin-14 as well as other partial cleavage products. Synonyms: Pyr-Glu-Arg-Pro-Pro-Leu-Gln-Gln-Pro-Pro-His-Arg-Asp-Lys-Lys-Pro-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Ser-Ser-Cys-Lys-OH (Disulfide bridge: Cys17-Cys28); 5-oxo-L-prolyl-L-α-glutamyl-L-arginyl-L-prolyl-L-prolyl-L-leucyl-L-glutaminyl-L-glutaminyl-L-prolyl-L-prolyl-L-histidyl-L-arginyl-L-α-aspartyl-L-lysyl-L-lysyl-L-prolyl-L-cysteinyl-L-lysyl-L-asparaginyl-L-phenylalanyl-L-phenylalanyl-L-tryptophyl-L-lysyl-L-threonyl-L-phenylalanyl-L-seryl-L-seryl-L-cysteinyl-L-lysine, cyclic (17→28)-disulfide; L-pyroglutamyl-L-alpha-glutamyl-L-arginyl-L-prolyl-L-prolyl-L-leucyl-L-glutaminyl-L-glutaminyl-L-prolyl-L-prolyl-L-histidyl-L-arginyl-L-alpha-aspartyl-L-lysyl-L-lysyl-L-prolyl-D-cysteinyl-D-lysyl-L-asparagyl-L-phenylalanyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-D-phenylalanyl-D-seryl-L-seryl-L-cysteinyl-L-lysine (17->28)-disulfide. Grade: ≥95%. CAS No. 1815618-17-7. Molecular formula: C161H240N46O41S2. Mole weight: 3540.05. | |
| Corynecin ? | It is produced by the strain of Corynebacterium KY-4339. It has weak activity against gram-positive bacteria and gram-negative bacteria. Synonyms: N-[(1R,2R)-1-[(Acetyloxy)methyl]-2-hydroxy-2-(4-nitrophenyl)ethyl]acetamide. Grade: >99% by HPLC. CAS No. 40958-11-0. Molecular formula: C13H16N2O6. Mole weight: 296.28. | |
| Corynecin I | It is produced by the strain of Corynebacterium KY-4339. It has weak activity against gram-positive bacteria and gram-negative bacteria. Synonyms: N-[(1R,2R)-2-Hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]acetamide; D-threo-2-Acetamido-1-(4-nitrophenyl)-1,3-propanediol; D-threo-2-Acetamido-1-p-nitrophenyl-1,3-propanediol; n-acetyl-p-nitrophenylserinol. Grade: >99% by HPLC. CAS No. 4423-58-9. Molecular formula: C11H14N2O5. Mole weight: 254.24. | |
| Corynecin II | It is produced by the strain of Corynebacterium KY-4339. It has weak activity against gram-positive bacteria and gram-negative bacteria. Synonyms: D-threo-1-p-Nitrophenyl-2-propionamido-1,3-propanediol; N-[(1R,2R)-2-Hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]propanamide; d-threo-2-(Propionamido)-1-(p-nitrophenyl)-1,3-propanediol. Grade: >99% by HPLC. CAS No. 35098-52-3. Molecular formula: C12H16N2O5. Mole weight: 268.27. | |
| Corynecin III | It is produced by the strain of Corynebacterium KY-4339. It has weak activity against gram-positive bacteria and gram-negative bacteria. Synonyms: Methamphenicol; dimethylamphenicol; N-[(1R,2R)-1-(Hydroxymethyl)-2-hydroxy-2-(4-nitrophenyl)ethyl]-2-methylpropanamide; N-[(1R,2R)-2-Hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]-2-methylpropanamide; d-threo-2-Isobutyramido-1-(p-nitrophenyl)-1,3-propanediol; N-[β-Hydroxy-α-(hydroxymethyl)-p-nitrophenethyl]-2-methyl-D-threo-propionamide. Grade: >99% by HPLC. CAS No. 18048-95-8. Molecular formula: C13H18N2O5. Mole weight: 282.29. | |
| Corynecin V | It is produced by the strain of Corynebacterium KY-4339. It has weak activity against gram-positive bacteria and gram-negative bacteria. Synonyms: [R-(R*,R*)]-N-[1-[(Acetyloxy)methyl]-2-hydroxy-2-(4-nitrophenyl)ethyl]-propanamide. Grade: >99% by HPLC. CAS No. 40958-12-1. Molecular formula: C14H18N2O6. Mole weight: 310.30. | |
| Cotadutide | Cotadutide (MEDI 0382) is a subcutaneous GLP-1 and glucagon receptor dual agonist that can be used to treat type 2 diabetes. Synonyms: MEDI 0382. CAS No. 1686108-82-6. Molecular formula: C167H252N42O55. Mole weight: 3728.03. | |
| (±)-Cotinine-[d3] | (±)-Cotinine-[d3] is the labelled analogue of (±)-Cotinine, which is a major metabolite of nicotine in humans. Synonyms: (±)-Cotinine-(methyl-d3); 1-(Methyl-d3)-5-(3-pyridinyl)-2-pyrrolidinone; rac-Cotinine-d3; (±)-Cotinine-d3. Grade: 99% by CP; 99% atom D. CAS No. 110952-70-0. Molecular formula: C10H9D3N2O. Mole weight: 179.23. | |
| (±)-Cotinine-[d4] | (±)-Cotinine-[d4] is the labelled analogue of (±)-Cotinine, which is a major metabolite of nicotine in humans. Synonyms: Cotinine D4; (±)-Cotinine-2,4,5,6-d4 (pyridine-d4); rac-Cotinine-d4; 1-Methyl-5-(3-pyridinyl)-2-pyrrolidinone-d4; (±)-Cotinine-d4. Grade: >95%. CAS No. 350818-68-7. Molecular formula: C10H8D4N2O. Mole weight: 180.24. | |
| (±)-Cotinine-[methyl-d3] | (±)-Cotinine-[methyl-d3], is the labelled analogue of Cotinine, which is a metabolite of nicotine. Synonyms: (±)-Cotinine-(methyl-d3); Cotinine d3. Grade: 98% by CP; 99% atom D. CAS No. 202656-15-3. Molecular formula: C10H9D3N2O. Mole weight: 179.23. | |
| Cotrimoxazole | Cotrimoxazole is a fixed antibiotic composed of trimethoprim and sulfamethoxazole. It blocks the synthesis of nucleotides to inhibit cellular metabolism in bacteria. Synonyms: CO-Trimoxazole; Trimosulfa; Trimethoprimsulfa; Trimforte; Sulfamethoxazole-trimethoprim. CAS No. 8064-90-2. Molecular formula: C24H29N7O6S. Mole weight: 543.59. | |
| Coumermycin a1 | Coumemycin A1 is found to bind at a second ATP-binding site in the C-terminal domain of Hsp90, IC50 70 μmol/L. It is produced by the strain of Streptomyces rishirensis, Str. spinichromogene and Str. Spinicoumarensis. It has anti-gram positive bacteria, negative bacteria, mycobacterium (weak) activity, cross-resistance with Novobiocin. Uses: Topoisomerase ii inhibitors. Synonyms: coumermycin a1; COUMERMYCIN; 4434-05-3; Coumamycin; Coumamycine; Coumamycinum; Cumamicina; Sugordomycin D-1a; Coumamycin [INN]; Notomycin; Coumermycin (USAN); Coumermycin [USAN]; Notomycin A1; PCH9QZ1IIH; CHEMBL4555272; NSC 107412; C05073; D02333; Sugordomycin D-la; [(3R,4S,5R,6R)-5-hydroxy-6-[4-hydroxy-3-[[5-[[4-hydroxy-7-[(2R,3R,4S,5R)-3-hydroxy-5-methoxy-6,6-dimethyl-4-(5-methyl-1H-pyrrole-2-ca. Grade: >98%. CAS No. 4434-5-3. Molecular formula: C55H59N5O20. Mole weight: 1110.08. | |
| C-Peptide 1 (rat) | C-Peptide 1 (rat) specifically binds to G-protein-coupled membrane receptors in the nanomolar concentration range, and subsequently activates Ca2+-dependent intracellular signaling pathways. This leads to a stimulation of the activity of both Na+-K+-ATPase, and endothelial nitric oxide synthase. Administration of C-peptide to streptozotocin induced diabetic rats elicited a substantial increase in whole-body glucose turnover. Synonyms: Insulin 1 Precursor (57-87) (rat); H-Glu-Val-Glu-Asp-Pro-Gln-Val-Pro-Gln-Leu-Glu-Leu-Gly-Gly-Gly-Pro-Glu-Ala-Gly-Asp-Leu-Gln-Thr-Leu-Ala-Leu-Glu-Val-Ala-Arg-Gln-OH; L-alpha-glutamyl-L-valyl-L-alpha-glutamyl-L-alpha-aspartyl-L-prolyl-L-glutaminyl-L-valyl-L-prolyl-L-glutaminyl-L-leucyl-L-alpha-glutamyl-L-leucyl-glycyl-glycyl-glycyl-L-prolyl-L-alpha-glutamyl-L-alanyl-glycyl-L-alpha-aspartyl-L-leucyl-L-glutaminyl-L-threonyl-L-leucyl-L-alanyl-L-leucyl-L-alpha-glutamyl-L-valyl-L-alanyl-L-arginyl-L-glutamine. Grade: ≥95%. CAS No. 41475-27-8. Molecular formula: C140H228N38O51. Mole weight: 3259.53. | |
| C-Peptide 2 (rat) | C-Peptide 2 (rat), a peptide composed of 31 amino acid residues, can effectively improve glucose utilization in streptozotocin induced diabetic rats. It is a component of proinsulin, and can inhibit glucose-induced insulin secretion. Synonyms: Preproinsulin 2 (57-87) (rat); H-Glu-Val-Glu-Asp-Pro-Gln-Val-Ala-Gln-Leu-Glu-Leu-Gly-Gly-Gly-Pro-Gly-Ala-Gly-Asp-Leu-Gln-Thr-Leu-Ala-Leu-Glu-Val-Ala-Arg-Gln-OH; L-alpha-glutamyl-L-valyl-L-alpha-glutamyl-L-alpha-aspartyl-L-prolyl-L-glutaminyl-L-valyl-L-alanyl-L-glutaminyl-L-leucyl-L-alpha-glutamyl-L-leucyl-glycyl-glycyl-glycyl-L-prolyl-glycyl-L-alanyl-glycyl-L-alpha-aspartyl-L-leucyl-L-glutaminyl-L-threonyl-L-leucyl-L-alanyl-L-leucyl-L-alpha-glutamyl-L-valyl-L-alanyl-L-arginyl-L-glutamine; Insulin 2 Precursor (57-87) (rat); Proinsulin 2 (33-63) (rat). Grade: ≥95% by HPLC. CAS No. 41594-08-5. Molecular formula: C135H222N38O49. Mole weight: 3161.43. | |
| CRAMP-18 (mouse) | CRAMP-18 (mouse) corresponds to the functional region of the antimicrobial peptide CRAMP and has strong antibacterial activity against a variety of bacteria, with no hemolytic activity (MIC = 12.5-50 μM). Synonyms: H-Gly-Glu-Lys-Leu-Lys-Lys-Ile-Gly-Gln-Lys-Ile-Lys-Asn-Phe-Phe-Gln-Lys-Leu-OH; glycyl-L-alpha-glutamyl-L-lysyl-L-leucyl-L-lysyl-L-lysyl-L-isoleucyl-glycyl-L-glutaminyl-L-lysyl-L-isoleucyl-L-lysyl-L-asparagyl-L-phenylalanyl-L-phenylalanyl-L-glutaminyl-L-lysyl-L-leucine. Grade: 95%. CAS No. 256639-17-5. Molecular formula: C101H171N27O24. Mole weight: 2147.64. | |
| C-Reactive Protein (CRP) 201-206 | C-Reactive Protein (CRP) 201-206 is the 201-206 fragment of CRP, which is a classic marker of inflammation and a cardiovascular risk marker, and may contribute to atherosclerosis. Synonyms: H-Lys-Pro-Gln-Leu-Trp-Pro-OH; L-lysyl-L-prolyl-L-glutaminyl-L-leucyl-L-tryptophyl-L-proline; C-reactive protein fragment 201-206. Grade: ≥95%. CAS No. 130348-99-1. Molecular formula: C38H57N9O8. Mole weight: 767.91. | |
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