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Dihydrostreptomycin
It is produced by the strain of Streptomyces humidus. Dihydrostreptomycin is an aminoglycoside antibiotic with a bactericidal property. It is used in the treatment of tuberculosis. Its antibacterial activity is similar to Streptomycin, and cross-resistance with Streptomycin. Synonyms: Dihydrostreptomycine; Abiocine; Vibriomycin; DST; D-Streptamine, O-2-deoxy-2-(methylamino)-α-L-glucopyranosyl-(1→2)-O-5-deoxy-3-C-(hydroxymethyl)-α-L-lyxofuranosyl-(1→4)-N,N'-bis(aminoiminomethyl)-; O-2-Deoxy-2-(methylamino)-α-L-glucopyranosyl-(1→2)-O-5-deoxy-3-C-(hydroxymethyl)-α-L-lyxofuranosyl-(1→4)-N1,N3-bis(aminoiminomethyl)-D-streptamine; Streptomycin, deoxydihydrohydroxy-; Streptomycin, dihydro-; 2,4-Diguanidino-3,5,6-trihydroxycyclohexyl-5-deoxy-2-O-(2-deoxy-2-methylamino-α-L-glucopyranosyl)-3-hydroxymethyl-β-L-lyxo-pentanofuranoside; DHSM. Grade: ≥95%. CAS No. 128-46-1. Molecular formula: C21H41N7O12. Mole weight: 583.59.
Dihydrostreptomycin sesquisulfate
Dihydrostreptomycin sesquisulfate is a semi-synthetic aminoglycoside antibiotic. Dihydrostreptomycin sesquisulfate is a derivative of Streptomycin used to treat bacterial diseases in cattle, pigs and sheep. Uses: An aminoglycoside antibiotic. Synonyms: D-Streptamine, O-2-deoxy-2-(methylamino)-α-L-glucopyranosyl-(1→2)-O-5-deoxy-3-C-(hydroxymethyl)-α-L-lyxofuranosyl-(1→4)-N1,N3-bis(aminoiminomethyl)-, sulfate (2:3); D-Streptamine, O-2-deoxy-2-(methylamino)-α-L-glucopyranosyl-(1→2)-O-5-deoxy-3-C-(hydroxymethyl)-α-L-lyxofuranosyl-(1→4)-N,N'-bis(aminoiminomethyl)-, sulfate (2:3) (salt); Streptomycin, dihydro-, sulfate (2:3) (salt); Didromycin; Didromycine; Dihydrostreptomycin 3/2 sulfate; Dihydrostreptomycin sulfate; Double-mycin; Panstreptin; Sol-Mycin; Streptomagna. Grade: ≥95%. CAS No. 5490-27-7. Molecular formula: C21H41N7O12.3/2H2O4S. Mole weight: 730.71.
Dihydrostreptomycin sulfate
Dihydrostreptomycin is a semi-synthetic aminoglycoside antibiotic, a derivative of streptomycin, which has a bactericidal effect and is used to treat tuberculosis. Synonyms: D-Streptamine, O-2-deoxy-2-(methylamino)-α-L-glucopyranosyl-(1→2)-O-5-deoxy-3-C-(hydroxymethyl)-α-L-lyxofuranosyl-(1→4)-N1,N3-bis(aminoiminomethyl)-, sulfate (1:x); D-Streptamine, O-2-deoxy-2-(methylamino)-α-L-glucopyranosyl-(1→2)-O-5-deoxy-3-C-(hydroxymethyl)-α-L-lyxofuranosyl-(1→4)-N,N'-bis(aminoiminomethyl)-, sulfate (salt); Streptomycin, dihydro-, sulfate (salt). CAS No. 1425-61-2. Molecular formula: C21H41N7O12.xH2O4S. Mole weight: 583.60 (free base).
Diketone-PEG12-Biotin
Diketone-PEG12-Biotin is a polyethylene glycol (PEG)-based PROTAC linker. Diketone-PEG12-Biotin can be used in the synthesis of a series of PROTACs. Molecular formula: C49H82N4O17S. Mole weight: 1031.26.
Diketone-PEG4-Biotin
Diketone-PEG4-Biotin is a polyethylene glycol (PEG)-based PROTAC linker. Diketone-PEG4-Biotin can be used in the synthesis of a series of PROTACs. CAS No. 2353409-85-3. Molecular formula: C33H50N4O9S. Mole weight: 678.84.
Di-Methylated Fidaxomicin
A derivative of Fidaxomicin. Fidaxomycin is a natural macrocyclic antibiotic that inhibits RNA polymerase with selectivity for Gram-positive bacteria over Gram-negative bacteria. Synonyms: 3''',5'''-Dideshydroxy-3''',5'''-dimethoxy Fidaxomicin. Grade: > 95%. CAS No. 185248-68-4. Molecular formula: C54H78Cl2O18. Mole weight: 1086.12.
Dimethyl-Bisphenol A
Dimethyl-Bisphenol A. Synonyms: Dimethyl-Bisphenol A; Bisphenol A dimethylether. Grade: 95%. CAS No. 1568-83-8. Molecular formula: C17H20O2. Mole weight: 256.34.
Dimethyl DL-glutamate hydrochloride
Dimethyl DL-glutamate is a cell-permeant glutamic acid derivative that enhances insulin release in response to glucose in isolated islets and in animal models of diabetes. It also potentiates the insulinotropic potential of glyburide and glucagon-like peptide Dimethyl DL-glutamate is used as a cell-permeable form of glutamate in studies of glutamate action in β-cells. Synonyms: Glutamic acid dimethyl ester; Dimethyl 2-aminopentanedioate; Dimethyl 2-aminopentanedioate hydrochloride; H-DL-Glu(OMe)-OMe.HCl; H-DL-Glu(Ome)-Ome. Grade: ≥ 98% (HPLC). CAS No. 13515-99-6. Molecular formula: C7H13NO4·HCl. Mole weight: 211.6.
Dimethyl-pyridin-4-yl-amine (DMAP)
Dimethyl-pyridin-4-yl-amine is a highly efficient catalyst for acylation reactions. Uses: A highly efficient catalyst for acylation reactions. Synonyms: 4-(dimethylamino)-pyridin; 4-Dimethylaminepyridine; gamma-(Dimethylamino)pyridine; N,N-Dimethyl-4-aminopyridine; n,n-dimethyl-4-pyridinamin; p-Dimethylaminopyridine; Pyridine, 4-(dimethylamino)-; AURORA KA-6495; DMAP; 4-dimethylaminopyridine; 4-DMAP; γ-(Dimethylamino)pyridine; Dimethylaminopyridine; USP Valacyclovir Related Compound G; Valaciclovir EP Impurity G; Valacyclovir USP Related Compound G. Grade: 98%. CAS No. 1122-58-3. Molecular formula: C7H10N2. Mole weight: 122.17.
Dimetridazole
Dimetridazole is an anti-fungal and anti-protozoal drug. It is a nitroimidazole class drug. Dimenidazole is an effective anti-histonia and anti-treponema pallidum agent. Uses: Antibacterial and anticoccidial activity. Synonyms: 1,2-dimethyl-5-nitro-1h-imidazole; TIMTEC-BB SBB006915; 1,2-dimethyl-5-nitro-1h-imidazol; 1,2-dimethyl-5-nitro-imidazol; 1H-Imidazole, 1,2-dimethyl-5-nitro-. Grade: >98%. CAS No. 551-92-8. Molecular formula: C5H7N3O2. Mole weight: 141.13.
Dinactin
A member of the macrotetrolide complex produced by a range of streptomyces species; a monovalent cation ionophore with high selectivity for ammonium and potassium; inhibits T-cell proliferation induced by IL-2 and cytokine production at nanomolar levels for IL-2, IL-4, IL-5 and interferon-γ. It is also resistant to gram-positive bacteria and mycobacteria. Synonyms: GNF-Pf-90; Antibiotic 170t; NSC63925; 4,13,22,31,37,38,39,40-Octaoxapentacyclo(32.2.1.17,10.116,19.125,28)tetracontane-3,12,21,30-tetrone, 5,23-diethyl-2,11,14,20,29,32-hexamethyl-(VAN) (8CI). Grade: >95% by HPLC. CAS No. 20261-85-2. Molecular formula: C42H68O12. Mole weight: 764.98.
Diniconazole
Diniconazol is a chemical compound belonging to chlorine group of conazole. It is used as a fungicide. It inhibited lanosterol 14 alpha-demethylation catalyzed by a yeast cytochrome P-450 strongly. Uses: Pesticide. Synonyms: (E)-(±)-β-[(2,4-Dichlorophenyl)methylene]-α-(1,1-dimethylethyl)-1H-1,2,4-triazole-1-ethanol; (E)-1-(2,4-Dichlorophenyl)-4,4-dimethyl-2-(1,2,4-triazol-1-yl)-1-penten-3-ol; (E)-β-[(2,4-Dichlorophenyl)methylene]-α-(1,1-dimethylethyl)-1H-1,2,4-triazole-1-ethanol; Mixor; Nb 2; Rac-diniconazole; S 3308; S 3308-10; S 3308L; Spotless; Sumi; Sumi 8; Sumi 8-020FS; Sumi 8-12.5WP; XE 779; 1H-1,2,4-Triazole-1-ethanol, β-[(2,4-dichlorophenyl)methylene]-α-(1,1-dimethylethyl)-, (βE)-. Grade: ≥95%. CAS No. 83657-24-3. Molecular formula: C15H17Cl2N3O. Mole weight: 326.22.
Dipeptide diaminobutyroyl benzylamide diacetate
Dipeptide diaminobutyroyl benzylamide is a biomimetic peptide and a muscarinic acetylcholine receptor antagonist. It mimics the action of the temple viper venom peptide Waglerin-1 to block sodium uptake and induce muscle relaxation. A cosmetic formulation acts as an anti-wrinkle ingredient used in anti-aging products. Synonyms: H-β-Ala-Pro-Dab-NH-benzyl acetate; H-β-Ala-Pro-DabNHBz acetate; Syn-Ake acetate; Snake trippetide acetate; (2S)-beta-Alanyl-L-prolyl-2,4-diamino-N-(phenylmethyl)butanamide acetate; BCP18324; Butanamide, β-alanyl-L-prolyl-2,4-diamino-N-(phenylmethyl)-, (2S)-, acetate (1:2); Butanamide, β-alanyl-L-prolyl-2,4-diamino-N-(phenylmethyl)-, (2S)-, diacetate; Dipeptide diaminobutyryl benzylamide diacetate; SYN-AKE. Grade: ≥98%. CAS No. 823202-99-9. Molecular formula: C19H29N5O3.2C2H4O2. Mole weight: 495.57.
dipotassium4-[5-benzylidene-3-(4-carboxylato-3-nitrophenyl)-2,4,6-trioxo-1,3-diazinan-1-yl]-2-nitrobenzoate. CAS No. 78506-80-6. Molecular formula: C25H12K2N4O11. Mole weight: 622.58.
Diprotin A
It is produced by the strain of Bacillus cereus BMF 657-RF1. It can inhibit Dipeptidyl amino peptidase IV and immune enhancement effect. Synonyms: Ile-Pro-Ile; isoleucylprolylisoleucine; l-isoleucyl-l-prolyl-l-isoleucine; N-(1-L-Isoleucyl-L-prolyl)-L-isoleucine; isoleucyl-prolyl-isoleucine; L-Isoleucine, N-(1-L-isoleucyl-L-prolyl)-; (2S,3S)-2-((S)-1-((2S,3S)-2-Amino-3-methylpentanoyl)pyrrolidine-2-carboxamido)-3-methylpentanoic acid; H-Ile-Pro-Ile-OH. Grade: ≥95%. CAS No. 90614-48-5. Molecular formula: C17H31N3O4. Mole weight: 341.45.
Dirithromycin
Dirithromycin is a macrolide glycopeptide antibiotic by binding to the 50S subunit of the 70S bacterial ribosome to inhibit the translocation of peptides. Dirithromycin binds to the 50S subunit of the 70S bacterial ribosome, and thus inhibits the translocation of peptides. Uses: Anti-bacterial agents. Synonyms: LY-237216; LY 237216; LY237216; Antibiotic AS-E 136; (1R,2R,3R,6R,7S,8S,9R,10R,12R,13S,15R,17S)-7-[(2,6-Dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-3-ethyl-2,10-dihydroxy-15-[(2-methoxyethoxy)methyl]-2,6,8,10,12,17-hexamethyl-9-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-4,16-dioxa-14-azabicyclo[11.3.1]heptadecan-5-one; Erythromycin, 9-deoxo-11-deoxy-9,11-[imino[2-(2-methoxyethoxy)ethylidene]oxy]-, [9S(R)]-; ASE 136; Dirythromycin; Dynabac; KT 237216; Noriclan; Nortron; Valodin. Grade: >98%. CAS No. 62013-04-1. Molecular formula: C42H78N2O14. Mole weight: 835.07.
Disitertide
Disitertide is a peptide transforming growth factor-β1 (TGF-β1) inhibitor, PI3K inhibitor and apoptosis inducer. Synonyms: P144; P144 Peptide. Grade: >97%. CAS No. 272105-42-7. Molecular formula: C68H109N17O22S2. Mole weight: 1580.8.
Disodium 4,4'-(3H-2,1-benzoxathiol-3-ylidene)bisphenolate s,s-dioxide. CAS No. 93839-72-6. Molecular formula: C19H14 O5 S. 2 Na. Mole weight: 398.34012.
Disodium (R)-2-Hydroxyglutarate
Disodium (R)-2-Hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases with Ki of 0.628 mM. In U-87MG cells, (R)-2-Hydroxyglutarate acts as a weak antagonist of α-KG to inhibit α-KG-dependent histone demethylases and increase dimethylation on both H3K9 and H3K79. Synonyms: MDK4906; MDK 4906; MDK-4906; d-α-hydroxyglutaric acid disodium salt; (2R)-2-Hydroxyglutaric Acid Disodium Salt; D-alpha-Hydroxyglutaric acid (disodium salt). Grade: 98%. CAS No. 103404-90-6. Molecular formula: C5H6Na2O5. Mole weight: 192.08.
Distamycin A
It is produced by the strain of Streptomyces distallicus NCIB 8936. It has the activity against gram-positive bacterium, mycobacterium, dermatophyte and Trichophyte. It has inhibitory effects on solid tumors such as Epstein-Barr ascites carcinoma, sarcoma 180, Walker 258, oberling-Guerin osteoma, and also inhibits vaccinosis virus, herpes simplex virus, adenovirus, and mouse hepatitis virus in cell culture. Synonyms: Distamycin; Distamycin-3; stallimycin; Herperetin; DST-A; Estalimicina; Stallimicina; Stallimycinum; 2N-(3,3-aminoiminopropyl)-4-[4-(4-formamido-1-methyl-1H-2-pyrrolylcarboxamido)-1-methyl-1H-2-pyrrolylcarboxamido]-1-methyl-1H-2-pyrrolecarboxamide. Grade: 95%. CAS No. 636-47-5. Molecular formula: C22H27N9O4. Mole weight: 481.51.
Dithioerythritol
Reagent for the reduction of disulfide group. Prevents oxidation of sulfhydryl-containing proteins during SDS-polyacrylamide gel electrophoresis. Cleavage of disulfide bonds in proteins. Uses: White crystals. Synonyms: 1,4-Dithioerythritol; (2R,3S)-1,4-bis(sulfanyl)butane-2,3-diol. Grade: ≥98%. CAS No. 6892-68-8. Molecular formula: C4H10O2S2. Mole weight: 154.25.
DL-DESTHIOBIOTIN
DL-DESTHIOBIOTIN. CAS No. 636-20-4. Molecular formula: C10H18N2O3. Mole weight: 214.27.
DL-Leucine
DL-Leucine, an isomer of Leucine, is a chemosterilant and dietary additive. DL-Leucine inhibits growth of Escherichia coli HfrH by 92.08%. Synonyms: DL-Leu-OH; (RS)-2-Amino-4-methylpentanoic acid. Grade: ≥ 98.5% (Assay). CAS No. 328-39-2. Molecular formula: C6H13NO2. Mole weight: 131.18.
DL-Nipecotic acid
Nipecotic acid, a potent inhibitor of neuronal and glial-aminobutyric acid (GABA) uptake in vitro, directly activates GABAA-like chloride channels with an EC50 of about 300 μM. Synonyms: (±)-β-Homoproline; Hexahydronicotinic acid; 3-Carboxypiperidine; Nipecotic acid; (±)-3-Piperidine carboxylic acid; (±)-Nipecotic acid; (±)-Piperidine-3-carboxylic acid. Grade: ≥95%. CAS No. 498-95-3. Molecular formula: C6H11NO2. Mole weight: 129.16.
DLPC (1,2-Dilauroyl-sn-glycero-3-phosphocholine) is a LRH-1 agonist and the dilauroyl diester of phosphatidylcholine, one of the most common cell membrane lipids. Synonyms: Dilauroyl phosphatidylcholine; 1,2-Didodecanoyl-sn-glycero-3-phosphocholine; 1,2-Dilauroyl-sn-glycero-3-PC; L-α-Dilauroyl Phosphatidylcholine; L-α-Dilauroylglyceryl-3-phosphorylcholine. Grade: ≥98%. CAS No. 18194-25-7. Molecular formula: C32H64NO8P. Mole weight: 621.83.
DL-Penicillamine
DL-Penicillamine is a penicillin metabolite used in the treatment of Wilson's disease, Cystinuria, Scleroderma and arsenic poisoning. Uses: Antidotes. Synonyms: 3,3-Dimenthyl-DL-cysteine; DL-2-Amino-3-mercapto-3-methylbutanoic acid; 3-Mercapto-DL-valine; (±)-Penicillamine; 2-Amino-3-mercapto-3-methylbutyric Acid; 3,3-Dimethylcysteine; DL-3-Mercaptovaline; DL-β-Mercaptovaline; DMC; NSC 22880; NSC 44656; dl-DMC; β,β-Dimethylcysteine; β-Mercaptovaline; β-Thiovaline; 2-amino-3-methyl-3-sulfanylbutanoic acid. Grade: ≥95%. CAS No. 52-66-4. Molecular formula: C5H11NO2S. Mole weight: 149.21.
DL-Serine
Serine is a non-essential amino acid and a natural ligand and allosteric activator of pyruvate kinase M2. Synonyms: DL-Serine; 302-84-1; 2-Amino-3-hydroxypropanoic acid; Serine DL-form; Serine, DL-; SERINE, (L); DL-2-Amino-3-hydroxypropionic Acid; MFCD00064223; serin; L-Serine-2-13c-15N; 00PAR1C66F; 3-Hydroxyalanine; SERINE, L-[3-3H]; DL-SERINE (1-13C); NSC-9960; (+/-)-2-Amino-3-hydroxypropionic acid; H-DL-Ser-OH.beta.-Hydroxyalanine; d,l-serine; L-Serine-3,3-d2; UNII-00PAR1C66F; NSC77689; CCRIS 5422; NSC-776. Grade: ≥95%. CAS No. 302-84-1. Molecular formula: C28H26F3N5O3. Mole weight: 537.5.
DL-threo-Droxidopa
A synthetic amino acid precursor of Norepinephrine. Antiparkinsonian. Uses: A synthetic amino acid precursor of norepinephrine. antiparkinsonian. Synonyms: (βS)-rel-β,3-Dihydroxy-D-tyrosine; DL-threo-3-(3,4-Dihydroxyphenyl)serine; DL-DOPS; L-Threodops; DL-threo-3,4-Dihydroxyphenylserine; DL-threo-DOPS; threo-2-Amino-3-(3,4-dihydroxyphenyl)-3-hydroxypropionic Acid; threo-β-(3,4-dihydroxyphenyl)-DL-serine. Grade: 95%. CAS No. 3916-18-5. Molecular formula: C9H11NO5. Mole weight: 213.19.
DM1 with a reactive linker SMCC, which can react with antibody to make antibody drug conjugate, as a potent EGFR inhibitor and it overcomes resistant to EGFR. Uses: This active molecular is dm1 with a linker smcc that can react with antibody to make antibody drug conjugate. Synonyms: 2,5-dioxopyrrolidin-1-yl 4-((3-((3-(((2S)-1-(((14S,16S,33S,2R,4R,10E,12Z,14R)-86-chloro-14-hydroxy-85,14-dimethoxy-33,2,7,10-tetramethyl-12,6-dioxo-7-aza-1(6,4)-oxazinana-3(2,3)-oxirana-8(1,3)-benzenacyclotetradecaphane-10,12-dien-4-yl)oxy)-1-oxopropan-2-yl)(methyl)amino)-3-oxopropyl)thio)-2,5-dioxopyrrolidin-1-yl)methyl)cyclohexane-1-carboxylate; DM1 SMCC; SMCC-DM1. Grade: 95%. CAS No. 1228105-51-8. Molecular formula: C51H66ClN5O16S. Mole weight: 1072.62.
DM4
DM4 is an anti-tubulin agent that inhibits cell division. DM4 can be used to prepare antibody-drug conjugates. DM4 binds to tubulin at the maytansine-binding site, disrupting microtubule assembly/disassembly dynamics and inhibiting mitosis. Synonyms: Maytansinoid DM 4; Maytansine, N2'-deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)-; N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)-maytansine; Ravtansine. Grade: ≥95%. CAS No. 796073-69-3. Molecular formula: C38H54ClN3O10S. Mole weight: 780.37.
DMT-Biotin
DMT-Biotin. CAS No. 144095-63-6. Molecular formula: C31H34N2O5S. Mole weight: 546.68.
DMT-Biotin-TEG
DMT-Biotin-TEG. CAS No. 1093231-05-0. Molecular formula: C37H47N3O7S. Mole weight: 677.85.
DMT-C3(Biotin)-CPG is used to attach biotin with a C3 spacer to the 3' end of an oligonucleotide.
D-NAME hydrochloride
N(G)-Nitro-D-arginine methyl ester (D-NAME) is the less active enantiomer of the nitric oxide (NO) synthase inhibitor N(G)-nitro-L-arginine methyl ester (L-NAME). D-NAME was initially thought to be inactive and was often used as a negative control for L-NAME. Synonyms: D-NG-Nitroarginine methyl ester; N(G)-Nitro-D-Arginine methyl ester; D-NAME, NG-Nitro-D-arginine methyl ester hydrochloride. Grade: ≥95%. CAS No. 50912-92-0. Molecular formula: C7H15N5O4·HCl. Mole weight: 269.7.
DO3A tert-Butyl ester
DOTA tert-Butyl ester is a benxyl derivative of the cyclic tosamide; can be nitrated directly; is more convenient to incorporate the nitro group after deprotection lithium aluminum hydride. Synonyms: Tri-tert-butyl 1,4,7,10-tetraazacyclododecane-1,4,7-triacetate; DO3A-t-Bu-ester; 1,4,7,10-Tetraazacyclododecane-1,4,7-triacetic Acid Tri-tert-butyl Ester. Grade: >98%. CAS No. 122555-91-3. Molecular formula: C26H50N4O6. Mole weight: 514.70.
Docetaxel Related Compound 1 ((2R, 3S)-3-Phenylisoserine)
Intermediate for the synthesis of taxol. Synonyms: (2R,3S)-3-Amino-2-hydroxy-3-phenyl-propanoic acid. Grade: ≥ 98% (NMR). CAS No. 136561-53-0. Molecular formula: C9H11NO3. Mole weight: 181.19.
Dolastatin 10
Dolastatin 10 is a potent antimitotic peptide from a marine animal, strongly inhibiting microtubule assembly. Uses: Adcs cytotoxin. Synonyms: DLS 10; NSC 376128; Dolastatin-10; DLS-10; DLS10; NSC376128; NSC-376128; L-Valinamide, N,N-dimethyl-L-valyl-N-[2-methoxy-4-[2-[1-methoxy-2-methyl-3-oxo-3-[[2-phenyl-1-(2-thiazolyl)ethyl]amino]propyl]-1-pyrrolidinyl]-1-(1-methylpropyl)-4-oxobutyl]-N-methyl-,[2S-[1[1R*(R*),2S*],2R*[1S*,2S*,3(R*)]]]-. Grade: >98%. CAS No. 110417-88-4. Molecular formula: C42H68N6O6S. Mole weight: 785.09.
DOPE-PEG-Biotin
DOPE-PEG-Biotin is a heterobifunctional PEGylation reagent with an unsaturated DOPE phospholipid and a biotin. It can be used in targeted drug delivery with the lipid bilayer. Synonyms: 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-(polyethylene glycol)-Biotin.
Doramectin
Doramectin is a derivative of ivermectin, which is an anthelmintic. Doramectin is an antiparasitic antibiotic produced by Streptomyces. Synonyms: UK67994. Grade: 95%. CAS No. 117704-25-3. Molecular formula: C50H74O14. Mole weight: 899.11.
DOTATATE acetate is a radiolabeled somatostatin analog used in medical imaging and therapy for neuroendocrine tumors (NETs). DOTATATE acetate is a peptide derivative that binds selectively to somatostatin receptors (mainly subtype 2), which are overexpressed on the surface of neuroendocrine tumor cells. This allows for specific targeting of these tumors. Synonyms: L-Threonine, N-[[4,7,10-tris(carboxymethyl)-1,4,7,10-tetraazacyclododec-1-yl]acetyl]-D-phenylalanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-threonyl-L-cysteinyl-, cyclic (2→7)-disulfide, acetate (salt) (1:x); DOTA-(Tyr3,Thr8)-Octreotide acetate; DOTA-[Tyr3] Octreotide Acid (Octreotate) acetate; DOTA-octreotate acetate; DOTA-[Tyr3]-Octreotide Acid acetate. Grade: 98%. CAS No. 177943-89-4. Molecular formula: C65H90N14O19S2.xC2H4O2. Mole weight: 1435.63 (free base).
Doxorubicin
Doxorubicin is an anthracycline antibiotic produced in Str. peucetius var. caesinus. Doxorubicin has anti-Gram-positive bacteria activity and has a broad anti-tumor spectrum. Doxorubicin is an antibiotic agent that inhibits DNA topoisomerase II and induces DNA damage and apoptosis. Uses: Adcs cytotoxin. Synonyms: Daunorubicin Impurity D; Daunorubicin EP Impurity D; (8S,10S)-10-[(3-Aamino-2,3,6-trideoxy-α-L-lyxohexopyranosyl)oxy]-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione; Adriamycin; Doxil; Adriablastin; Doxorubicine; Adriblastina; 14-Hydroxydaunomycin; 14-Hydroxydaunorubicine; Caelyx; Hydroxydaunorubicin; 5,12-Naphthacenedione, 10-((3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-, (8S-cis)-; NSC 123127; (1S,3S)-3,5,12-Trihydroxy-3-(hydroxyacetyl)-10-(methyloxy)-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranoside; Epirubicin EP Impurity C. Grade: >98%. CAS No. 23214-92-8. Molecular formula: C27H29NO11. Mole weight: 543.52.
Doxorubicin hydrochloride
Doxorubicin is an anthracycline antibiotic with antineoplastic activity produced by the bacterium Streptomyces peucetius var. Doxorubicin is an antibiotic agent that inhibits DNA topoisomerase II and induces DNA damage and apoptosis. Uses: Adcs cytotoxin. Synonyms: Daunorubicin EP Impurity D hydrochloride; (8S,10S)-10-[(3-Aamino-2,3,6-trideoxy-α-L-lyxohexopyranosyl)oxy]-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione hydrochloride; Doxorubicine hydrochloride; Adriblastina hydrochloride; 14-Hydroxydaunomycin hydrochloride; 14-Hydroxydaunorubicine hydrochloride; Hydroxydaunorubicin hydrochloride; (1S,3S)-3,5,12-Trihydroxy-3-(hydroxyacetyl)-10-(methyloxy)-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranoside hydrochloride; Epirubicin EP Impurity C hydrochloride. Grade: >98%. CAS No. 25316-40-9. Molecular formula: C27H30ClNO11. Mole weight: 579.98.
Doxorubicinol hydrochloride
Doxorubicinol is the major metabolite of doxorubicin, which inhibits DNA topoisomerase II by inducing double-stranded DNA breaks. Synonyms: (8S,10S)-10-[(3-Amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-8-[(1S)-1,2-dihydroxyethyl]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione Hydrochloride; Adriamycinol Hydrochloride; 13-Dihydrodoxorubicin Hydrochloride; (1S,3S)-3-[(1S)-1,2-Dihydroxyethyl]-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydro-1-tetracenyl 3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranoside hydrochloride (1:1); 5,12-Naphthacenedione, 10-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-8-[(1S)-1,2-dihydroxyethyl]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-, (8S,10S)-, hydrochloride (1:1). Grade: ≥90%. CAS No. 63950-05-0. Molecular formula: C27H32ClNO11. Mole weight: 582.00.
Doxycycline
It is produced by the strain of Oxytetracycline or Methacycline. It is regarded as the third generation of tetracycline. It shows broad spectrum antibacterial and antiprotozoan activity and acts by binding to the 30S and 50S ribosomal subunits, blocking protein synthesis. Its antibacterial spectrum is similar to Tetracycline, its antibacterial activity is 2-8 times of Tetracycline, its plasma elimination half-life is as long as 18-22h, and it has little effect on renal function. Synonyms: 6-Deoxy-5-hydroxytetracycline; 6-Deoxyoxytetracycline; Doxytetracycline; Hydramycin; Medeomycin; Vibramycin; Doxycyclinum; Monodox; Oracea; Doxy-Caps; Vibravenos; 5-Hydroxy-alpha-6-deoxytetracycline; 6-alpha-Deoxy-5-oxytetracycline. Grade: >98% by HPLC. CAS No. 564-25-0. Molecular formula: C22H24N2O8. Mole weight: 444.44.
Doxycycline EP Impurity A
Doxycycline EP Impurity A is an impurity of Doxycycline, which is a semisynthetic, broad-spectrum tetracycline antibiotic used in the treatment of infections caused by bacteria and certain parasites. Synonyms: 6-Epidoxycycline; Doxycycline hyclate EP impurity A; Doxycycline monohydrate EP impurity A; 6β-Deoxy-5-hydroxytetracycline; 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, (4S,4aR,5S,5aR,6S,12aS)-; (4S,4aR,5S,5aR,6S,12aS)-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide; 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, 6-epimer; 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, [4S-(4α,4aα,5α,5aα,6β,12aα)]-; 6-epi-Doxycycline; 6-epi-Oxytetracycline, 6-deoxy-; 6-Epioxytetracycline, 6-deoxy-; epi-Doxycycline; β-6-Deoxy-5-hydroxytetracycline; Doxycycline Related Compound A; Doxycycline USP Related Compound A. Grade: ≥95%. CAS No. 3219-99-6. Molecular formula: C22H24N2O8. Mole weight: 444.43.
Doxycycline EP Impurity B
Meclocycline is a semi-synthetic tetracycline prepared by dehydrating the 6-hydroxyl group of oxytetracycline. It has a wide range of antibacterial and antiprotozoal activities. Meclocycline is an impurity of Doxycycline, which is a semisynthetic, broad-spectrum tetracycline antibiotic used in the treatment of infections caused by bacteria and certain parasites. Uses: Antibiotics, tetracycline. Synonyms: Doxycycline hyclate EP impurity B; Doxycycline monohydrate EP impurity B; 6-Methyleneoxytetracycline; Metacycline; Rondomycin; 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methylene-1,11-dioxo-, (4S,4aR,5S,5aR,12aS)-; (4S,4aR,5S,5aR,12aS)-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methylene-1,11-dioxo-2-naphthacenecarboxamide; 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methylene-1,11-dioxo-, [4S-(4α,4aα,5α,5aα,12aα)]-; 6-Demethyl-6-deoxy-5-hydroxy-6-methylenetetracycline; 6-Deoxy-6-methylene-6-demethyl-5-hydroxytetracycline; 6-Methylene-5-hydroxytetracycline; 6-Methyleneoxytetracycline; Bialatan; GS 2876; Oxytetracycline, 6-methylene-; Rondomycin; Tri-methacycline. Grade: >98% by HPLC. CAS No. 914-00-1. Molecular formula: C22H22N2O8. Mole weight: 442.42.
Doxycycline hydrochloride
It is produced by the strain of Oxytetracycline or Methacycline. It is regarded as the third generation of tetracycline. It shows broad spectrum antibacterial and antiprotozoan activity and acts by binding to the 30S and 50S ribosomal subunits, blocking protein synthesis. Its antibacterial spectrum is similar to Tetracycline, its antibacterial activity is 2-8 times of Tetracycline, its plasma elimination half-life is as long as 18-22h, and it has little effect on renal function. It can be used for the prevention and treatment of domestic animal respiratory diseases and mixed infection of bacterial diseases when respiratory diseases occur. Uses: Anti-bacterial agents. Synonyms: Doxylin; samecin; 6-deoxy-5-oxytetracycline hydrochloride; novadox; liomycin; retens; Doxycycline HCl; tecacin; mespafin; Doxigalumicina; Doxylin; Deoxy-5-hydroxytetracycline hydrochloride. Grade: >98%. CAS No. 10592-13-9. Molecular formula: C22H25ClN2O8. Mole weight: 480.89.
[D-p-Cl-Phe6,Leu17]-VIP
[D-p-Cl-Phe6,Leu17]-VIP is a selective vasoactive intestinal peptide (VIP) receptor antagonist (IC50 = 125.8 nM) with no activity at glucagon, secretin or GRF receptors. Synonyms: [D-p-Cl-Phe6, Leu17]-Vasoactive Intestinal Peptide human, porcine, rat. CAS No. 102805-45-8. Molecular formula: C148H239ClN44O42. Mole weight: 3342.24.
DPDPE
DPDPE is a synthetic enkephalin peptide and acts as a δ-opioid receptor agonist. Opioid receptors are divided into three types called, μ, κ and δ, depending upon their ligands. DPDPE has greater than 250-fold selectivity for the δ-opioid receptor over the μ- and κ-opioid receptors in rat brain homogenates (Kis = 713 and >1,500 nM, respectively). Uses: Neurotransmitter agents. Synonyms: DPDPE; [D-Pen2,5]Enkephalin; [D-Pen2,D-Pen5]Enkephalin. Grade: ≥95%. CAS No. 88373-73-3. Molecular formula: C30H39N5O7S2. Mole weight: 645.79.
(D-Phe5,Cys6,11,N-Me-D-Trp8)-Somatostatin-14 (5-12) amide, a synthetic somatostatin analogue, is selective for human somatostatin receptor subtype 5 (hsst5) and has similar binding affinity to somatostatin-28, with Kd±SEM values of 1200, 23.5±3.92, 11.05±1.03, >1000 and 0.61±0.36 nM for hsst1, hsst2, hsst3, hsst4 and hsst5, respectively. Synonyms: (N-Me-D-Trp4,Thr8)-Octreotide amide; H-D-Phe-Cys-Phe-N-Me-D-Trp-Lys-Thr-Cys-Thr-NH2 (Disulfide bridge: Cys2-Cys7); D-phenylalanyl-L-cysteinyl-L-phenylalanyl-N-methyl-D-tryptophyl-L-lysyl-L-threonyl-L-cysteinyl-L-threoninamide (2->7)-disulfide. Grade: ≥95% by HPLC. CAS No. 340821-13-8. Molecular formula: C50H67N11O10S2. Mole weight: 1046.26.
(D-Phe6,Leu-NHEt13,des-Met14)-Bombesin (6-14)
(D-Phe6,Leu-NHEt13,des-Met14)-Bombesin (6-14) is an antagonist of bombesin receptor with IC50 values for cellular secretion and growth approaching the picomolar region. Synonyms: D-Phenylalanyl-L-glutaminyl-L-tryptophyl-L-alanyl-L-valylglycyl-L-histidyl-N-ethyl-L-leucinamide; H-D-Phe-Gln-Trp-Ala-Val-Gly-His-Leu-NHEt; L-Leucinamide, D-phenylalanyl-L-glutaminyl-L-tryptophyl-L-alanyl-L-valylglycyl-L-histidyl-N-ethyl-; DPDMB. Grade: 95%. CAS No. 124199-90-2. Molecular formula: C49H69N13O9. Mole weight: 984.15.
D-Phenylalanine
D-Phenylalanine, a carboxypeptidase A, endorphinase and enkephalinase inhibitor, enhances endorphin production and diminishes pain. Uses: Antidepressant. Synonyms: ZK 3059; ZK3059; ZK-3059. Grade: >98%. CAS No. 673-06-3. Molecular formula: C9H11NO2. Mole weight: 165.19.
D-(+)-Phenyllactic acid
D-(+)-Phenyllactic acid, an antibacterial agent excreted by Geotrichum candidum, inhibits a range of gram-positive bacteria in humans and foodstuffs as well as gram-negative bacteria found in humans. Synonyms: D-3-Phenyllactic acid; D-(+)-3-Phenyllactic Acid; (+)-2-Hydroxy-3-phenylpropanoic Acid; (+)-2-Hydroxy-3-phenylpropionic Acid; (+)-β-Phenyllactic Acid; (2R)-2-Hydroxy-3-phenylpropionic Acid; (2R)-3-Phenyl-2-hydroxypropanoic Acid; (R)-2-Hydroxy-3-phenylpropionic Acid; (R)-3-Phenyl-2-hydroxypropanoic Acid; (R)-3-Phenyl-2-hydroxypropionic Acid; (R)-3-Phenyllactic Acid; (R)-Phenyllactic Acid; (R)-α-Hydroxy-3-phenylpropionic Acid; (R)-β-Phenyllactic Acid; D-2-Hydroxy-3-phenylpropionic Acid; D-β-Phenyllactic Acid; β-Phenyl-D-lactic Acid. Grade: ≥95%. CAS No. 7326-19-4. Molecular formula: C9H10O3. Mole weight: 166.17.
DPPE-cap-Biotinyl
DPPE-cap-Biotinyl is a biotinylated phospholipid. It has been used in PEGylated polyamidoamine-dendrimer-conjugated supported lipid bilayers (SLB) to isolate circulating tumor cells and tumor cell microembolis from patient-derived blood by antibody-coated microfluidics. It has also been used as a component of SLBs to detect protein-ligand binding with ortho-conjugated Texas Red DHPE. Synonyms: 1,2-Dipalmitoyl-sn-glycero-3-PE-N-(cap biotin) (sodium salt); 16:0 Biotinyl Cap PE. Grade: >98%. CAS No. 384835-52-3. Molecular formula: C53H98N4NaO11PS. Mole weight: 1053.39.
Drimentine A
It is produced by the strain of Actinomycete strain MST-8651. It belongs to a novel class of antibiotics, possessing a new terpenylated diketopiperazine structure, with antibacterial, antifungal and anthelmintic activity. Synonyms: (3S,5aS,10bS,11aS)-10b-[[(1S,4aS,8aS)-Decahydro-5,5,8a-trimethyl-2-methylene-1-naphthalenyl]methyl]-6,10b,11,11a-tetrahydro-3-(2-methylpropyl)-2H-pyrazino[1',2':1,5]pyrrolo[2,3-b]indole-1,4(3H,5aH)-dione; [3S-[3α,5aα,10bα(1R*,4aR*,8aR*),11aβ]]-10b-[(Decahydro-5,5,8a-trimethyl-2-methylene-1-naphthalenyl)methyl]-6,10b,11,11a-tetrahydro-3-(2-methylpropyl)-2H-pyrazino[1',2':1,5]pyrrolo[2,3-b]indole-1,4(3H,5aH)-dione. Grade: >98% by HPLC. CAS No. 204398-90-3. Molecular formula: C32H45N3O2. Mole weight: 503.72.
Drimentine B
It is produced by the strain of Actinomycete strain MST-8651. It belongs to a novel class of antibiotics, possessing a new terpenylated diketopiperazine structure, with antibacterial, antifungal and anthelmintic activity. Synonyms: [5aS-[5aα,6aβ(1R*,4aR*,8aR*),11aβ]]-6a-[(Decahydro-5,5,8a-trimethyl-2-methylene-1-naphthalenyl)methyl]-6,6a,11,11a-tetrahydro-3H-pyrrolo[1'',2'':4',5']pyrazino[1',2':1,5]pyrrolo[2,3-b]indole-5,13(2H,5aH)-dione. Grade: >98% by HPLC. CAS No. 204398-91-4. Molecular formula: C31H39N3O2. Mole weight: 485.66.
Drimentine C
It is produced by the strain of Actinomycete strain MST-8651. It belongs to a novel class of antibiotics, possessing a new terpenylated diketopiperazine structure, with antibacterial, antifungal and anthelmintic activity. Synonyms: [5aS-[5aα,6aβ(1R*,4aR*,8aR*),11aβ,13aα]]-6a-[(Decahydro-5,5,8a-trimethyl-2-methylene-1-naphthalenyl)methyl]-2,3,6,6a,11,11a-hexahydro-1H-pyrrolo[1'',2'':4',5']pyrazino[1',2':1,5]pyrrolo[2,3-b]indole-5,13(5aH,13aH)-dione; (5aS,6aS,11aS,13aS)-6a-(((1S,4aS,8aS)-5,5,8a-trimethyl-2-methylenedecahydronaphthalen-1-yl)methyl)-1,2,3,6,6a,11,11a,13a-octahydro-13H-pyrrolo[1'',2'':4',5']pyrazino[1',2':1,5]pyrrolo[2,3-b]indole-5,13(5aH)-dione. Grade: >98% by HPLC. CAS No. 204398-92-5. Molecular formula: C31H41N3O2. Mole weight: 487.68.
DSPE-Biotin has strong binding with avidin or streptavidin for protein labelling or purification. The compound has phospholipid group with a hydrophilic phosphate connected to two fatty acids by a glycerol molecule. In water, the molecule can orient itself into lipid bilayer and can be used for drug encapsulation, such as drug loaded liposomes or nanoparticles. Please contact us for GMP-grade inquiries. Synonyms: (2R)-3-((hydroxy(2-(5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)ethoxy)phosphoryl)oxy)propane-1,2-diyl distearate; 133695-76-8. Grade: 0.98. CAS No. 133695-76-8. Molecular formula: C51H96N3O10PS. Mole weight: 974.4.
DSPE-PEG (2000) Biotin
DSPE-PEG(2000) Biotin has been used in the generation of biotinylated liposome. Synonyms: 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[biotinyl(polyethylene glycol)-2000] (ammonium salt). Grade: >90%. CAS No. 385437-57-0. Molecular formula: C142H280N5O56PS. Mole weight: 3016.82.
DSPE-PEG-Biotin, MW 1k-5K
DSPE-PEG-Biotin is a heterobifunctional PEG derivative. Heterobifunctional PEG can be attached to different molecules or materials to extend the richness of different molecular combinations. Phospholipids are amphiphilic. It is a preferred material for the formation of liposomes. It can be used to target drug research or cross-linking of protein carriers and ligands. It can also be used in cell culture, pharmaceutical research, drug delivery and release, nanotechnology and new materials. Mole weight: Customizable.
(D-Trp6)-LHRH (free acid)
An impurity of Triptorelin and a luteinizing hormone-releasing hormone (LHRH) agonist. Synonyms: pGlu-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly; Luteinizing hormone-releasing factor (swine), 6-D-tryptophan-10-glycine- (9CI). Grade: 98%. CAS No. 129418-54-8. Molecular formula: C64H81N17O14. Mole weight: 1312.43.
[D-Trp8]-γ-MSH
[D-Trp8]-γ-MSH is a selective melanocortin 3 (MC3) receptor agonist (IC50= 6.7, 340 and 600 nM for human MC3, MC5 and MC4 receptors respectively). It displays antiinflammatory efficacy in mice bearing a non-functional MC1R (recessive yellow e/e mouse) and these effects are abrogated in the presence of the HO-1 inhibitor ZnPPIX. Synonyms: L-tyrosyl-L-valyl-L-methionyl-glycyl-L-histidyl-L-phenylalanyl-L-arginyl-D-tryptophyl-L-alpha-aspartyl-L-arginyl-L-phenylalanyl-glycine. CAS No. 321351-81-9. Molecular formula: C74H99N21O16S. Mole weight: 1570.79.
[D-Trp8]-γ-MSH acetate
[D-Trp8]-γ-MSH acetate is a selective melanocortin 3 (MC3) receptor agonist (IC50 = 6.7, 340 and 600 nM for human MC3, MC5 and MC4 receptors, respectively). It displays antiinflammatory efficacy in mice bearing a non-functional MC1R (recessive yellow e/e mouse) and these effects are abrogated in the presence of the HO-1 inhibitor ZnPPIX. Synonyms: CTX-1100 acetate; L-Tyrosyl-L-valyl-L-methionylglycyl-L-histidyl-L-phenylalanyl-L-arginyl-D-tryptophyl-L-α-aspartyl-L-arginyl-L-phenylalanylglycine acetate; H-Tyr-Val-Met-Gly-His-Phe-Arg-D-Trp-Asp-Arg-Phe-Gly-OH.CH3CO2H. Grade: ≥95%. Molecular formula: C76H103N21O18S. Mole weight: 1630.82.
[D-Trp8]-γ-MSH TFA
[D-Trp8]-γ-MSH is a selective melanocortin 3 (MC3) receptor agonist (IC50 values are 6.7, 340 and 600 nM for human MC3, MC5 and MC4 receptors respectively). It displays anti-inflammatory efficacy. Synonyms: CTX-1100 trifluoroacetate; L-Tyrosyl-L-valyl-L-methionylglycyl-L-histidyl-L-phenylalanyl-L-arginyl-D-tryptophyl-L-α-aspartyl-L-arginyl-L-phenylalanylglycine trifluoroacetate; H-Tyr-Val-Met-Gly-His-Phe-Arg-D-Trp-Asp-Arg-Phe-Gly-OH.TFA. Grade: ≥95%. Molecular formula: C76H100F3N21O18S. Mole weight: 1684.79.