BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Aranorosin | Aranorosin is a fungal metabolite originally isolated from P. roseus and an inhibitor of anti-apoptotic functions regulated by Bcl-2. It has antimicrobial activity against B. subtilis, A. niger, and C. albicans when used at a concentration of 1 mg/ml. Aranorosin also reduces viability in apoptosis-resistant HeLa/Bcl-2 cells. Aranorosin also inhibits enzyme AAC(6')/APH(2'') which plays a role in arbekacin (ABK)-resistance in MRSA. Synonyms: Spiro[4,8-dioxatricyclo[5.1.0.03,5]octane-2,2'(3'H)-furan], 2,4-dodecadienamide deriv.; Aranorosine. Grades: ≥95%. CAS No. 117184-53-9. Molecular formula: C23H33NO6. Mole weight: 419.51. |  |
| Aranorosinol A | Aranorosinol A is an antibiotic produced by Pseudoarachniotus roseus. It has only weak antibacterial and antifungal activity. CAS No. 145147-04-2. Molecular formula: C23H35NO6. Mole weight: 421.53. | |
| Aranorosinol B | Aranorosinol B is an antibiotic produced by Pseudoarachniotus roseus. It has only weak antibacterial and antifungal activity. CAS No. 145147-05-3. Molecular formula: C26H39NO7. Mole weight: 477.59. | |
| Aranotin | Aranotin is an antibiotic produced by the shell of the cyst Arachniotus aureus. Aranotin inhibits viral RNA synthesis by impeding the activity of RNA-dependent RNA polymerase. Aranotin have antiviral effects and can inhibit the formation of plaques of type I, II, and III poliovirus. Grades: >98%. Molecular formula: C20H18N2O7S2. Mole weight: 462.50. | |
| AR-AO 14418-[d3] | AR-AO 14418-[d3] is a labelled analogue of AR-AO 14418, a Glycogen Synthase Kinase 3β (GSK-3β) inhibitor. Synonyms: AR-AO 14418-d3; AR-A014418-d3. CAS No. 1216908-63-2. Molecular formula: C12H9D3N4O4S. Mole weight: 311.33. | |
| Arasertaconazole | Arasertaconazole is the (R)-enantiomer of Sertaconazole, an imidazole antifungal agent that inhibits the synthesis of ergosterol, an essential cell wall component of fungi. Synonyms: (R)-Sertaconazole; 1-[(2R)-2-[(7-Chlorobenzo[b]thien-3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl]-1H-Imidazole. Grades: > 95%. CAS No. 583057-48-1. Molecular formula: C20H15Cl3N2OS. Mole weight: 437.78. | |
| Arasin-1 | Arasin-1 is a proline-arginine-rich antimicrobial peptide isolated from the spider crab, Hyas araneus. It has a large activity spectrum with activity against Gram-positive, Gram-negative bacteria, as well as against fungi. | |
| Arasin 2 | Arasin 2 is produced by Hyas araneus. Arasin 2 is an antimicrobial peptide that has a large activity spectrum with activity against Gram-positive, Gram-negative bacteria, as well as against fungi. It does not show hemolytic activity. Synonyms: Ara-2; Proline/arginine-rich antimicrobial peptide. | |
| Arasin-likeSp | A synthetic arasin-likeSp peptide revealed the antimicrobial activity against both Gram-positive and Gram-negative bacteria including some crustacean pathogens (A. viridans, Vibrio harveyi and V. anguillarum). | |
| ara UTP | Ara UTP, a potent nucleotide analog known for its excellent substrate activity towards RNA polymerases, has garnered significant research interest in the field of medical science. Its diverse applicability ranges from elucidating RNA editing and splicing mechanisms to synthesizing modified RNA molecules, thus serving as an invaluable tool for researchers. Furthermore, the promising antiviral activity of Ara UTP has been explored as a potential therapeutic option for hepatitis C virus infections, opening up new avenues for clinical intervention. Synonyms: arabinofuranosyluridine triphosphate; [[(2R,3S,4S,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate. CAS No. 60102-52-5. Molecular formula: C9H15N2O15P3. Mole weight: 484.139. | |
| Ara-UTP | Ara-UTP can be used as an antiviral nucleotide. Synonyms: Arauridine-5'-Triphosphate. Grades: ≥90% by AX-HPLC. Molecular formula: C9H15O15N2P3. Mole weight: 484.1. | |
| Arbekacin | Arbekacin(INN) is a semisynthetic aminoglycoside antibiotic. It is primarily used for the treatment of infections caused by multi-resistant bacteria including methicillin-resistant Staphylococcus aureus(MRSA). Grades: >98%. CAS No. 51025-85-5. Molecular formula: C22H44N6O10. Mole weight: 552.31. | |
| Arbekacin sulfate | Arbekacin is a semi-synthetic aminoglycoside antibiotic used to treat infections caused by methicillin-resistant Staphylococcus aureus (MRSA). Synonyms: Habekacin. CAS No. 104931-87-5. Molecular formula: C22H46N6O14S. Mole weight: 650.70. | |
| Arbidol Impurity 1 | Arbidol Impurity 1 is an impurity of Arbidol, a medicinal agent for treating viral infections. Synonyms: Demethyl Arbidol; 1130901-04-0. CAS No. 1130901-04-0. Molecular formula: C21H23BrN2O3S. Mole weight: 463.39. | |
| Arbidol Impurity 10 | Arbidol Impurity 10 is an impurity of Arbidol, a medicinal agent for treating viral infections. CAS No. 1312943-26-2. Molecular formula: C15H14Br3NO4. Mole weight: 511.99. | |
| Arbidol Impurity 11 | Arbidol Impurity 11 is an impurity of Arbidol, a medicinal agent for treating viral infections. CAS No. 1312943-27-3. Molecular formula: C15H14Br3NO4. Mole weight: 511.99. | |
| Arbidol Impurity 12 | Arbidol Impurity 12 is an impurity of Arbidol, a medicinal agent for treating viral infections. Molecular formula: C15H15Br2NO4. Mole weight: 433.09. | |
| Arbidol Impurity 13 | Arbidol Impurity 13 is an impurity of Arbidol, a medicinal agent for treating viral infections. Molecular formula: C13H13Br2NO3. Mole weight: 391.05. | |
| Arbidol Impurity 14 | Arbidol Impurity 14 is an impurity of Arbidol, a medicinal agent for treating viral infections. CAS No. 1332614-17-1. Molecular formula: C21H23BrN2O3S. Mole weight: 463.39. | |
| Arbidol Impurity 2 | Arbidol Impurity 2 is an impurity of Arbidol, a medicinal agent for treating viral infections. Synonyms: 25900-97-4; Arbidol Impurity 2; Oprea1_017206; Oprea1_800726; SCHEMBL12567455. CAS No. 25900-97-4. Molecular formula: C22H26N2O3S. Mole weight: 398.52. | |
| Arbidol Impurity 3 | Arbidol Impurity 3 is an impurity of Arbidol, a medicinal agent for treating viral infections. CAS No. 958450-23-2. Molecular formula: C22H23BrN2O3S. Mole weight: 475.40. | |
| Arbidol Impurity 4 | Arbidol Impurity 4 is an impurity of Arbidol, a medicinal agent for treating viral infections. Molecular formula: C20H20BrNO3S. Mole weight: 434.35. | |
| Arbidol Impurity 6 | Arbidol Impurity 6 is an impurity of Arbidol, a medicinal agent for treating viral infections. CAS No. 2107765-51-3. Molecular formula: C13H15NO3. Mole weight: 233.26. | |
| Arbidol Impurity 7 | Arbidol Impurity 7 is an impurity of Arbidol, a medicinal agent for treating viral infections. Synonyms: 5-Acetoxy-6-bromo-2-bromomethyl-1-methyl-1H-indole-3-carboxylic acid, ethyl ester. Grades: 98 %. CAS No. 110543-98-1. Molecular formula: C15H15Br2NO4. Mole weight: 433.09. | |
| Arbidol Impurity 9 | Arbidol Impurity 9 is an impurity of Arbidol, a medicinal agent for treating viral infections. Molecular formula: C15H16BrNO4. Mole weight: 354.20. | |
| Arbidol Impurity A | Arbidol Impurity A is an impurity of Arbidol, a medicinal agent for treating viral infections. Molecular formula: C20H21BrN2O3S. Mole weight: 449.36. | |
| Arbidol Impurity B | 6-bromo-1,2,4-trimethyl-1H-indol-5-ol is an impurity of Arbidol, a medicinal agent for treating viral infections. Molecular formula: C11H12BrNO. Mole weight: 254.12. | |
| Arbidol Impurity C | Arbidol Impurity C is an impurity of Arbidol, a medicinal agent for treating viral infections. Molecular formula: C12H13BrN2O2. Mole weight: 297.15. | |
| Arbidol Impurity D | Arbidol Impurity D is an impurity of Arbidol, a medicinal agent for treating viral infections. Synonyms: 1,2,3,4-tetramethyl-1H-indol-5-ol. Molecular formula: C12H15NO. Mole weight: 189.25. | |
| Arbidol Impurity E | Arbidol Impurity E is an impurity of Arbidol, a medicinal agent for treating viral infections. Molecular formula: C12H13Br2NO. Mole weight: 347.05. | |
| Arbidol Impurity F HCl | Arbidol Impurity F HCl is an impurity of Arbidol, a medicinal agent for treating viral infections. Molecular formula: C20H22BrClN2O3S. Mole weight: 485.82. | |
| Arbidol Impurity I | A Impurity of Arbidol. Synonyms: ethyl 6,7-dibromo-4-((dimethylamino)methyl)-5-hydroxy-1-methyl-2-((phenylthio)methyl)-1H-indole-3-carboxylate. Grades: > 95%. CAS No. 153633-10-4. Molecular formula: C22H24Br2N2O3S. Mole weight: 556.32. | |
| Arbidol Impurity J | Arbidol Impurity J is an impurity of Arbidol, a medicinal agent for treating viral infections. Molecular formula: C16H20Br2N2O3. Mole weight: 448.15. | |
| Arbidol Sulfone | A Impurity of Arbidol. Synonyms: 6-Bromo-4-[(dimethylamino)methyl]-5-hydroxy-1-methyl-2-[(phenylsulfonyl)methyl]-1H-indole-3-carboxylic Acid Ethyl Ester. Grades: > 95%. CAS No. 151455-32-2. Molecular formula: C22H25BrN2O5S. Mole weight: 509.42. | |
| Arbidol Sulfoxide | A Impurity of Arbidol. Synonyms: 6-Bromo-4-[(dimethylamino)methyl]-5-hydroxy-1-methyl-2-[(phenylsulfinyl)methyl]-1H-indole-3-carboxylic Acid Ethyl Ester. Grades: > 95%. CAS No. 151455-33-3. Molecular formula: C22H25BrN2O4S. Mole weight: 493.42. | |
| Arborcandin A | Arborcandins are 1,3-β-glucan synthase inhibitors produced by the filamentous fungus SANK 17397. Synonyms: 21,24-Bis(carbamoylmethyl)-15-(2-carbamoyl-2-hydroxyethyl)-9,12-bis(1-hydroxyethyl)-6-(3-hydroxydodecyl)-27-(8-hydroxydodecyl)-18-methyl-1,4,7,10,13,16,19,22,25,28-decaazacyclohentriacontane-2,5,8,11,14,17,20,23,26,29-decone. Molecular formula: C57H101N13O18. Mole weight: 1256.48. | |
| Arborcandin B | Arborcandins are 1,3-β-glucan synthase inhibitors produced by the filamentous fungus SANK 17397. Synonyms: 21,24-Bis(carbamoylmethyl)-15-(2-carbamoyl-2-hydroxyethyl)-9,12-bis(1-hydroxyethyl)-6-(3-hydroxydodecyl)-27-(8-hydroxytridecyl)-18-methyl-1,4,7,10,13,16,19,22,25,28-decaazacyclohentriacontane-2,5,8,11,14,17,20,23,26,29-decone. Molecular formula: C58H103N13O18. Mole weight: 1270.51. | |
| AR-C 102222 | AR-C 102222 has been found to be an iNOS inhibitor and show antinociceptive and anti-inflammatory activity in rodent pain models. Synonyms: AR-C 102222; AR C 102222; ARC 102222; ARC102222; 5-[(4'-Amino-5',8'-difluorospiro[piperidine-4,2'(1'H)-quinaxolin]-1-yl)carbonyl]-2-pyridinecarbonitrile hydrochloride. Grades: ≥98% by HPLC. CAS No. 253771-21-0. Molecular formula: C19H16F2N6O.HCl. Mole weight: 418.83. | |
| AR-C117977 | AR-C117977 is a potent MCT1 inhibitor that inhibited the rat MLR and was more potent than cyclosporin A (CsA). AR-C117977 can reduce vimmune responses both in vitro and in vivo, maintains long-term graft survival, and induces operational tolerance. Synonyms: 5-((3-hydroxypropyl)thio)-1-isobutyl-3-methyl-6-(naphthalen-1-ylmethyl)thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione; AR-C-117977; AR-C 117977. Grades: >98%. CAS No. 216685-07-3. Molecular formula: C25H28N2O3S2. Mole weight: 468.63. | |
| AR-C124910XX-N-Glucuronide | An impurity of Ticagrelor which is a reversible P2Y12 receptor antagonist and compared with clopidogrel will result in a lower risk of recurrent thrombotic events in a broad patient population with ACS and that this result can be achieved with a clinically acceptable bleeding rate and overall safety profile. Synonyms: 6-(((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)(5-(propylthio)-3-((1R,2S,3R,4S)-2,3,4-trihydroxycyclopentyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)amino)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid. Grades: > 95%. Molecular formula: C27H32F2N6O9S. Mole weight: 654.65. | |
| AR-C124910XX-O-Glucuronide | An impurity of Ticagrelor which is a reversible P2Y12 receptor antagonist ticagrelor and is unique in its greater and more rapid and consistent, yet reversible, inhibition of the ADP receptor. Synonyms: 6-(((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)(5-(propylthio)-3-((1R,2S,3R,4S)-2,3,4-trihydroxycyclopentyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)amino)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid. Grades: > 95%. Molecular formula: C27H32F2N6O9S. Mole weight: 654.65. | |
| AR-C 141990 hydrochloride | Cas No. 2250019-94-2. | |
| AR-C155858 | AR-C155858 is a novel inhibitor of the monocarboxylate transporters (MCTs) MCT1 and MCT2, but exhibits no activity at MCT4. It can be used to probe MCTs' roles in the metabolic studies. Besides, AR-C155858 was found to have immunosuppressive activity and can inhibit the proliferation of T-lymphocytes. Synonyms: ARC155858; AR-C155858; ARC 155858. Grades: >98%. CAS No. 496791-37-8. Molecular formula: C21H27N5O5S. Mole weight: 461.53. | |
| ARCA | Used for in vitro transcription of 5'-capped mRNA to generate Cap 0 structure. ARCA can only be inserted in the correct direction, and the resulting mRNA is translated twice as efficiently as the mRNA initiated by mCAP. Synonyms: Anti Reverse Cap Analog; m7(3'-O-methy)G(5')ppp(5')G; 3´-O-Me-m7G(5')ppp(5')G. Grades: ≥95% by AX-HPLC. Molecular formula: C22H32N10O18P3 (free acid). Mole weight: 817.47 (free acid). | |
| ARCA Sodium | ARCA Sodium, a potent inhibitor of the Nav1.5 cardiac sodium channel, is adeptly utilized in mitigating arrhythmias, such as atrial fibrillation. Additionally, it exhibits promise as a therapeutic agent for the management of chronic pain conditions. Molecular formula: C22H29N10Na2O18P3. Mole weight: 860.42. | |
| archaeosine | Archaeosine, an essential compound, holds immense significance in the realm of biomedicine due to its potential therapeutic efficacy in a diverse array of ailments. A pivotal player in crafting targeted medications for cancer, neurological maladies, and infectious conditions, this product assumes a critical role in the advanced pharmaceutical landscape. Synonyms: 1H-Pyrrolo[2,3-d]pyrimidine-5-carboximidamide, 2-amino-4,7-dihydro-4-oxo-7-b-D-ribofuranosyl-; 2-Amino-4,7-dihydro-4-oxo-7-beta-D-ribofuranosyl-1H-pyrrolo(2,3-d)pyrimidine-5-carboximidamide; 2-amino-4-oxo-7-(beta-D-ribofuranosyl)-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidine-5-carboximidamide. CAS No. 148608-52-0. Molecular formula: C12H16N6O5. Mole weight: 324.3. | |
| ARD1 | ARD1 is isolated from Archaeoprepona demophoon. It possesses potent anti-fungal activity. | |
| Ardeemin | Ardeemin is a heterocyclic compound produced by Aspergillus fischeri var. brasiliensis AB 1826 M-35. Aldamide has no antibacterial activity and has no effect on multidrug-resistant (MDR) tumor cells, but its acetylated compound 5-N-acetylaldamide can improve its effect on multidrug-resistant tumor cells. Molecular formula: C26H26N4O2. Mole weight: 426.51. | |
| Arecoline | Arecoline has shown regulatory properties of controlling plasminogen activator inhibitor-1 expression in human buccal mucosa fibroblasts. Uses: Cholinergic agonists. Synonyms: 1-Methyl-1,2,5,6-tetrahydro-pyridine-3-carboxylic Acid Methyl Ester; 3-Methoxycarbonyl-1-methyl-1,2,5,6-tetrahydropyridine; Arecaidine Methyl Ester. Grades: > 95%. CAS No. 63-75-2. Molecular formula: C8H13NO2. Mole weight: 155.2. | |
| Arecoline-[O-methyl-d3] Hydrochloride | Synonyms: Arecoline Hydrochloride-d3. Grades: 98% by CP; 98% atom D. Molecular formula: C8H11D3ClNO2. Mole weight: 194.67. | |
| Arenobufagin 3-hemisuberate | Arenobufagin 3-hemisuberate is a natural compound of the steroid class isolated from the glandular body of Bufo gargarizans Cantor. Synonyms: (3beta,5beta,11alpha)-3-[(7-Carboxy-1-oxoheptyl)oxy]-11,14-dihydroxy-12-oxo-bufa-20,22-dienolide. Grades: >98%. CAS No. 30219-16-0. Molecular formula: C32H44O9. Mole weight: 572.69. | |
| ARF-binding protein 1 (757-766) | ARF-binding protein 1 (757-766) is a 10-aa peptide. ARF-binding protein 1 regulates the trafficking of proteins between the trans-Golgi network and the lysosome. | |
| Arg-Arg-AMC HCl | Synonyms: H-Arg-Arg-AMC · 3 HCI; L-Arginyl-L-arginine 7-amido-4-methylcoumarin trihydrochloride. CAS No. 201847-69-0. Molecular formula: C22H36Cl3N9O4. Mole weight: 596.94. | |
| Arg-Asp-OH | Synonyms: L-Arginyl-L-aspartic acid. Grades: ≥97% (HPLC). CAS No. 15706-88-4. Molecular formula: C10H19N5O5. Mole weight: 289.29. | |
| Argatroban | Argatroban is an anticoagulant that is a small molecule direct thrombin inhibitor. Uses: Antithrombins; platelet aggregation inhibitors. Synonyms: (2R,4R)-1-[(2S)-5-[(Aminoiminomethyl)amino]-1-oxo-2-[[(1,2,3,4-tetrahydro-3-methyl-8-quinolinyl)sulfonyl]amino]pentyl]-4-methyl-2-piperidinecarboxylic Acid. Grades: >98%. CAS No. 74863-84-6. Molecular formula: C23H36N6O5S. Mole weight: 508.63. | |
| Argatroban Impurity 4 | Cas No. 153886-68-1. | |
| Argatroban Impurity 6 | A metabolite of Argatroban. Synonyms: 5-Quinolinesulfonyl chloride, 3-methyl-. Grades: > 95%. CAS No. 94975-84-5. Molecular formula: C10H8ClNO2S. Mole weight: 241.7. | |
| Argatroban Impurity A | A metabolite of Argatroban. Synonyms: (2R,4R)-1-[(2S)-5-[(Aminoiminomethyl)amino]-2-[[(3-methyl-8-quinolinyl)sulfonyl]amino]-1-oxopentyl]-4-methyl-2-piperidinecarboxylic Acid. Grades: > 95%. CAS No. 951130-92-0. Molecular formula: C23H32N6O5S. Mole weight: 504.61. | |
| Argatroban Impurity B | A metabolite of Argatroban. Synonyms: Mixture of Diastereomers. Grades: > 95%. CAS No. 188659-43-0. Molecular formula: C22H34N4O5S. Mole weight: 466.6. | |
| Argatroban (L,2R,4S)-isomer | Argatroban (L,2R,4S)-isomer is an impurity of Argatroban, a synthetic thrombin inhibitor and antithrombotic agent. Synonyms: (2R,4S)-4-methyl-1-(((3-methyl-1,2,3,4-tetrahydroquinolin-8-yl)sulfonyl)-L-arginyl)piperidine-2-carboxylic acid; (2R,4S)-1-((2S)-5-Guanidino-2-(3-methyl-1,2,3,4-tetrahydroquinoline-8-sulfonamido)pentanoyl)-4-methylpiperidine-2-carboxylic Acid; Argatroban (L,2R,4S)-Isomer (Mixture of Diastereomers). CAS No. 189264-04-8. Molecular formula: C23H36N6O5S. Mole weight: 508.63. | |
| Argatroban monohydrate | Argatroban is an anticoagulant that acts as a potent, seletive, univalent direct inhibitor of thrombin. Argatroban was approved in 2000 for prophylaxis or treatment of thrombosis in patients with heparin-induced thrombocytopenia (HIT). Synonyms: (2R,4R)-1-[(2S)-5-(diaminomethylideneamino)-2-[[(3R)-3-methyl-1,2,3,4-tetrahydroquinolin-8-yl]sulfonylamino]pentanoyl]-4-methyl-piperidine-2-carboxylic acid hydrate; MCI-9038; MCI 9038; MCI9038; MD805; MD-805; MD 805; DK-7419; DK 7419; DK7419; GN1600; GN-1600; GN 1600; MMTQAP; MPQA; OM 805; Slonnon; Argipidine; Argatroban monohydrate. Grades: 98%. CAS No. 141396-28-3. Molecular formula: C23H38N6O6S. Mole weight: 526.65. | |
| Argatroban Related Compound | An intermediate in the preparation of Argatroban. Synonyms: Ethyl (2S,4S)-4-Methylpipecolate; (2S,4S)-4-Methyl-2-piperidinecarboxylic Acid Ethyl Ester; (2S-trans)-4-Methyl-2-piperidinecarboxylic Acid Ethyl Ester. Grades: > 95%. CAS No. 78306-52-2. Molecular formula: C9H17NO2. Mole weight: 171.24. | |
| Argatroban Related Compound 1 | A metabolite of Argatroban. Synonyms: Ethyl (2R,4S)-4-Methylpipecolate. Grades: > 95%. CAS No. 79199-61-4. Molecular formula: C9H17NO2. Mole weight: 171.24. | |
| Argatroban Related Compound 2 | A metabolite of Argatroban. Synonyms: Ethyl (2S,4R)-4-Methylpipecolate. Grades: > 95%. CAS No. 79199-62-5. Molecular formula: C9H17NO2. Mole weight: 171.24. | |
| Argatroban Related Impurity 2 | A metabolite of Argatroban. Synonyms: (2R,4R)-1-[(2S)-5-[(Aminoiminomethyl)amino]-1-oxo-2-[[[(3R)-1,2,3,4-tetrahydro-3-methyl-8-quinolinyl]sulfonyl]amino]pentyl]-4-methyl-2-piperidinecarboxylic Acid. Grades: > 95%. CAS No. 189264-02-6. Molecular formula: C23H36N6O5S. Mole weight: 508.64. | |
| Arg-Gly-Asp | RGD (Arg-Gly-Asp) Peptides is a cell adhesion motif which can mimic cell adhesion proteins and bind to integrins. Synonyms: Arginyl-Glycyl-Aspartic acid; RGD peptide. Grades: Min 98%. CAS No. 99896-85-2. Molecular formula: C12H22N6O6. Mole weight: 346.34. | |
| Arg-Gly-Asp-Ser | Arg-Gly-Asp-Ser is an integrin binding sequence that inhibits integrin receptor function. It is a tetrapeptide found on fibronectin, fibrinogen α, and von Willebrand factor, but not vitronectin or collagen. It decreases systemic inflammation via inhibition of collagen-triggered activation of leukocytes and attenuates expression of inflammatory cytokines, iNOS and MMP-9. It inhibits thrombin-induced binding of platelets to fibronectin, fibrinogen α, and von Willebrand factor. It promotes cell attachment and abrogates apoptosis via the mitochondrial pathway in osteoblasts in vitro. It also blocks the attachment of certain pathogens to cells. Uses: Platelet aggregation inhibitors. Synonyms: Arg Gly Asp Ser; RGDS peptide; Fibronectin Inhibitor. Grades: >98%. CAS No. 91037-65-9. Molecular formula: C15H27N7O8. Mole weight: 433.42. | |
| Arg-Gly-Asp TFA salt | Arg-Gly-Asp can be used as a brain tumor targeting ligand. Synonyms: RGD (Trifluoroacetate); RGD Trifluoroacetate; HY-P0278A. Grades: ≥98%. CAS No. 2378808-45-6. Molecular formula: C14H23F3N6O8. Mole weight: 460.36. | |
| Arg-Gly-Glu-Ser | Arg-Gly-Glu-Ser, a RGD-related peptide, is a control for the RGDS ihibitory activity on fibrinogen binding to activated platelets. Synonyms: H-Arg-Gly-Glu-Ser-OH; L-arginyl-glycyl-L-alpha-glutamyl-L-serine; (4S) -4-[[2-[[ (2S) -2-amino-5- (diaminomethylideneamino) pentanoyl]amino]acetyl]amino]-5-[[ (1S) -1-carboxy-2-hydroxyethyl]amino]-5-oxopentanoic acid; RGES. Molecular formula: C16H29N7O8. Mole weight: 447.45. | |
| Argifin | Argifin is a sub-nanomolar chitinase inhibitor produced by soil microorganisms, with IC50s of 0.025 μM, 6.4 μM , 1.1 μM and 4.5 μM for SmChiA (Serratia marcescens chitinaese A), SmChiB, Aspergillus fumigatus chitinase B1 and human chitotriosidase, respectively. CAS No. 243975-37-3. Molecular formula: C29H41N9O10. Mole weight: 675.69. | |
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