BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| (D-Trp8)-Somatostatin-14 | (D-Trp8)-Somatostatin-14, a somatostatin analogue, is 6-8 times more potent than somatostatin in inhibiting growth hormone, glucagon and insulin release. It may be better resistant to degradation of biological fluids. Synonyms: [DTrp8] Somatostatin; H-Ala-Gly-Cys-Lys-Asn-Phe-Phe-D-Trp-Lys-Thr-Phe-Thr-Ser-Cys-OH (Disulfide bridge: Cys3-Cys14); L-alanyl-glycyl-L-cysteinyl-L-lysyl-L-asparagyl-L-phenylalanyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-cysteine (3->14)-disulfide; 8-D-tryptophan-somatostatin; 8-Trp-SRIF-14. Grade: ≥95% by HPLC. CAS No. 58976-46-8. Molecular formula: C76H104N18O19S2. Mole weight: 1637.88. |  |
| Dulaglutide | Dulaglutide is a medication used for the treatment of type 2 diabetes in combination with diet and exercise. Synonyms: LY2189265. CAS No. 923950-08-7. | |
| (±)-Duloxetine-[d3] hydrochloride | (±)-Duloxetine-[d3] hydrochloride is the labelled impurity of Duloxetine. Duloxetine is a medication used to treat major depressive disorder, generalized anxiety disorder, fibromyalgia, and neuropathic pain. Synonyms: Duloxetine-D3 HCl; N-(Methyl-d3)-γ-(1-naphthalenyloxy)-2-thiophenepropanamine; (±)-Duloxetine-D3 HCl; N-(Methyl-d3)-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amine hydrochloride; N-(Methyl-d3)-3-(1-naphthoxy)-3-(2-thienyl)propylamine; (±)-Duloxetine-d3 hydrochloride. Grade: 95% by HPLC; 98% atom D. CAS No. 1188266-11-6. Molecular formula: C18H16D3NOS.HCl. Mole weight: 336.89. | |
| Duocarmycin A | It is produced by the strain of (Pyridamycin) Streptomyces sp. DO-88. It has strong antibacterial and antitumor activity. It can inhibit gram-positive bacteria such as Staphylococcus aureus and Streptococcus faecalis (MIC is less than 0.01 μg/mL), it can also inhibit klebsiella pneumoniae (MIC is 0.032 μg/mL), other bacteria and yeast (MIC is 1-10 μg/mL). Synonyms: Antibiotic DC 88A; methyl (6R,7bR,8aS)-6-methyl-4,7-dioxo-2-(5,6,7-trimethoxy-1H-indole-2-carbonyl)-1,2,4,5,6,7,8,8a-octahydrocyclopropa[c]pyrrolo[3,2-e]indole-6-carboxylate; Methyl (2R,3bR,4aS)-2-methyl-3,8-dioxo-6-[(5,6,7-trimethoxy-1H-indol-2-yl)carbonyl]-1,2,3,4,4a,5,6,8-octahydrocyclopropa[c]pyrrolo[3,2-e]indole-2-carboxylate; DUMA; (+)-Dunnione; (+)-duocarmycin A. Grade: ≥95%. CAS No. 118292-34-5. Molecular formula: C26H25N3O8. Mole weight: 507.49. | |
| Duocarmycin B1 | It is produced by the strain of (Pyridamycin) Streptomyces sp. DO-88. It has anti-gram-positive bacteria, gram-negative bacteria and tumor activity. Synonyms: Antibiotic DC 89B1; 1H-Pyrrolo3,2-fquinoline-2-carboxylic acid, 8-bromo-2,3,6,7,8,9-hexahydro-4-hydroxy-2-methyl-1-oxo-6-(5,6,7-trimethoxy-1H-indol-2-yl)carbonyl-, methyl ester, (2R,8S)-; Duocarmycin B(sub 1). Grade: ≥95%. CAS No. 124325-93-5. Molecular formula: C26H26BrN3O8. Mole weight: 588.40. | |
| Duramycin | It is produced by the strain of Streptomyces cinnamomeus. It has activity against gram-positive bacteria, gram-negative bacteria (individual, weak), Mycobacterium and Candida albicans. Synonyms: 27,46-(Methaniminopentaniminomethano)-6,43:15,40-bis(methanothiomethano)pyrrolo[2,1-d1][1,4,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,52]thiaheptadecaazacyclopentapentacontine, cyclic peptide deriv.; Antibiotic PA 48009; Lancovutide; Leucopeptin; Ancovenin, 2-L-lysine-6-(3-aminoalanine)-10-L-phenylalanine-12-L-phenylalanine-13-L-valine-15-(erythro-3-hydroxy-L-aspartic acid)-, cyclic 6-19)-imine; Duramycin A. Grade: ≥90%. CAS No. 1391-36-2. Molecular formula: C88H123N23O25S3. Mole weight: 1999.25. | |
| DX600 | DX600 is an inhibitor of angiotensin-converting enzyme 2 (ACE2). Synonyms: DX-600; Ac-Gly-Asp-Tyr-Ser-His-Cys-Ser-Pro-Leu-Arg-Tyr-Tyr-Pro-Trp-Trp-Lys-Cys-Thr-Tyr-Pro-Asp-Pro-Glu-Gly-Gly-Gly-NH2 (Disulfide bridge: Cys6-Cys17); N-{[(6S,9R,14R,17S,20S,23S,25aS,31S,34S,37S,40S,42aS)-9-[(N-Acetylglycyl-L-α-aspartyl-L-tyrosyl-L-seryl-L-histidyl)amino]-17-(4-aminobutyl)-37-(3-carbamimidamidopropyl)-31,34-bis(4-hydroxybenzyl)-6-(hydroxymethyl)-20,23-bis(1H-indol-3-ylmethyl)-40-isobutyl-5,8,16,19,22,25,30,33,36,39,42-undecaoxooctatriacontahydro-1H,13H-dipyrrolo[2,1-p:2',1'-e1][1,2,5,8,11,14,17,20,23,26,29,32,35]dithiaundecaazacyclooctatriacontin-14-yl]carbonyl}-L-threonyl-L-tyrosyl-L-prolyl-L-α-aspartyl-L-prolyl-L-α-glutamylglycylglycylglycinamide; N-acetyl-glycyl-L-alpha-aspartyl-L-tyrosyl-L-seryl-L-histidyl-L-cysteinyl-L-seryl-L-prolyl-L-leucyl-L-arginyl-L-tyrosyl-L-tyrosyl-L-prolyl-L-tryptophyl-L-tryptophyl-L-lysyl-L-cysteinyl-L-threonyl-L-tyrosyl-L-prolyl-L-alpha-aspartyl-L-prolyl-L-alpha-glutamyl-glycyl-glycyl-glycinamide (6->17)-disulfide. Grade: ≥95%. CAS No. 478188-26-0. Molecular formula: C141H185N35O40S2. Mole weight: 3074.32. | |
| DX600 TFA | DX600 TFA is an inhibitor of angiotensin-converting enzyme 2 (ACE2) and does not cross-react with ACE. Synonyms: Glycinamide, N-acetylglycyl-L-α-aspartyl-L-tyrosyl-L-seryl-L-histidyl-L-cysteinyl-L-seryl-L-prolyl-L-leucyl-L-arginyl-L-tyrosyl-L-tyrosyl-L-prolyl-L-tryptophyl-L-tryptophyl-L-lysyl-L-cysteinyl-L-threonyl-L-tyrosyl-L-prolyl-L-α-aspartyl-L-prolyl-L-α-glutamylglycylglycyl-, cyclic (6→17)-disulfide, trifluoroacetate salt (1:1); Ac-Gly-Asp-Tyr-Ser-His-Cys-Ser-Pro-Leu-Arg-Tyr-Tyr-Pro-Trp-Trp-Lys-Cys-Thr-Tyr-Pro-Asp-Pro-Glu-Gly-Gly-Gly-NH2.TFA (Disulfide bridge: Cys6-Cys17); N-acetyl-glycyl-L-alpha-aspartyl-L-tyrosyl-L-seryl-L-histidyl-L-cysteinyl-L-seryl-L-prolyl-L-leucyl-L-arginyl-L-tyrosyl-L-tyrosyl-L-prolyl-L-tryptophyl-L-tryptophyl-L-lysyl-L-cysteinyl-L-threonyl-L-tyrosyl-L-prolyl-L-alpha-aspartyl-L-prolyl-L-alpha-glutamyl-glycyl-glycyl-glycinamide (6->17)-disulfide trifluoroacetic acid. Grade: ≥95%. Molecular formula: C123H169F3N32O39S2. Mole weight: 2841.01. | |
| Dynamin inhibitory peptide | Has been found to be a peptide inhibitor of the GTPase dynamin and competitively blocks binding of dynamin to amphiphysin thus prevents endocytosis when administered intracellularly. Synonyms: Dynamin inhibitory peptide; 251634-21-6; L-Proline, L-glutaminyl-L-valyl-L-prolyl-L-seryl-L-arginyl-L-prolyl-L-asparaginyl-L-arginyl-L-alanyl-; QVPSRPNRAP; HY-P1083; AKOS024456770; MS-31983; CS-0027626. Grade: >98%. CAS No. 251634-21-6. Molecular formula: C47H80N18O14. Mole weight: 1121.26. | |
| Dynamin inhibitory peptide, myristoylated | An inhibitor of the GTPase dynamin that competitively blocks binding of dynamin to amphiphysin, preventing endocytosis. Synonyms: AKOS024456771; Dynamin inhibitory peptide,myristoylated; PD079118; S-251634-22-7. Grade: >99%. CAS No. 251634-22-7. Molecular formula: C61H107N19O14. Mole weight: 1330.64. | |
| Dynemicin A | It is produced by the strain of Micromonospora chersina sp. M 956-I and M. globosa. Dynemicin A has a strong killing effect on a variety of tumor cells at Pg/mL level. The cyclic enediyne part of enediyne antibiotics is cycled by Bergman to form aromatic diradicals, which quickly seize hydrogen atoms from the DNA skeleton and break the DNA strand, thus killing tumor cells. Synonyms: (1S,4R,4aR,14S,14aS)-1,4,4a,7,12,13,14,14a-Octahydro-6,8,11-trihydroxy-3-methoxy-1-methyl-7,12-dioxo-4a,14a-epoxy-4,14-(3-hexene-1,5-diyne-1,6-diyl)naphtho[2,3-c]phenanthridine-2-carboxylicacid; Dynemicin; BU 3420T. Grade: 95%. CAS No. 124412-57-3. Molecular formula: C30H19NO9. Mole weight: 537.47. | |
| Dynorphin (1-17) | Dynorphin A is a heptadecapeptide derived from the cleavage of prodynorphin and found widely distributed in the central nervous system. It acts as an endogenous kappa receptor agonist with nanomolar binding affinity. It also activates the human novel opioid receptor-like receptor of ORL1. It is resistant to enzymatic degradation and may have antinociceptive functions. Uses: Neurotransmitter agents. Synonyms: Dynorphin A (swine); Dynorphin A (pig); 1-17-Dynorphin; L-Glutamine, L-tyrosylglycylglycyl-L-phenylalanyl-L-leucyl-L-arginyl-L-arginyl-L-isoleucyl-L-arginyl-L-prolyl-L-lysyl-L-leucyl-L-lysyl-L-tryptophyl-L-α-aspartyl-L-asparaginyl-; Dyn-A17; Dynorphin 17; Dynorphin A; Dynorphin A (1-17); Dynorphin A (human); Dynorphin A (porcine); Dynorphin A (rat); Dynorphin A 1-17; Dynorphin-A (Bos taurus); Porcine dynorphin (1-17); Porcine dynorphin A (1-17); Proteins, Dyn-A17; Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-Trp-Asp-Asn-Gln. Grade: ≥95%. CAS No. 80448-90-4. Molecular formula: C99H155N31O23. Mole weight: 2147.51. | |
| Dynorphin A 1-10 | Dynorphin A 1-10 is an endogenous opioid neuropeptide that binds to the extracellular loop 2 of the κ-opioid receptor. It also blocks the NMDA activation current with IC50 of 42.0 μM. Synonyms: Dynorphin A, porcine, fragment 1-10; H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-OH; L-tyrosyl-glycyl-glycyl-L-phenylalanyl-L-leucyl-L-arginyl-L-arginyl-L-isoleucyl-L-arginyl-L-proline; Dynorphin A (1-10), porcine. Grade: ≥95%. CAS No. 79994-24-4. Molecular formula: C57H91N19O12. Mole weight: 1234.45. | |
| Dynorphin A 1-10 acetate | Dynorphin A (1-10) acetate is an endogenous opioid neuropeptide that binds to the extracellular loop 2 of the κ-opioid receptor. It also blocks the NMDA activation current with an IC50 of 42.0 μM. Synonyms: H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-OH.CH3CO2H; L-tyrosyl-glycyl-glycyl-L-phenylalanyl-L-leucyl-L-arginyl-L-arginyl-L-isoleucyl-L-arginyl-L-proline acetic acid; 1-10-Dynorphin A (swine) acetate; α-Neoendorphin (pig), 7-L-arginine-8-L-isoleucine-9-L-arginine-10-L-proline-, acetate (1:1); Porcine dynorphin A (1-10) acetate. Grade: ≥95%. Molecular formula: C59H95N19O14. Mole weight: 1294.53. | |
| Dynorphin A (1-13) | Dynorphin A is an endogenous opioid peptide that preferentially activates κ opioid receptors. Synonyms: Dynorphin A Porcine Fragment 1-13; Porcine dynorphin A(1-13); H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-OH; L-tyrosyl-glycyl-glycyl-L-phenylalanyl-L-leucyl-L-arginyl-L-arginyl-L-isoleucyl-L-arginyl-L-prolyl-L-lysyl-L-leucyl-L-lysine; 1-13-Dynorphin A (swine). Grade: 98%. CAS No. 72957-38-1. Molecular formula: C75H126N24O15. Mole weight: 1603.95. | |
| Dynorphin A (1-8) | Dynorphin A (1-8) is an opioid octapeptide that exhibits agonist activity at μ and δ receptors. Synonyms: Dynorphin A fragment 1-8 porcine; H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-OH. Grade: 98%. CAS No. 75790-53-3. Molecular formula: C46H72N14O10. Mole weight: 981.15. | |
| Dynorphin A acetate | Dynorphin A acetate is a heptadecapeptide derived from the cleavage of prodynorphin and found widely distributed in the central nervous system. It acts as an endogenous kappa receptor agonist with nanomolar binding affinity. It also activates the human novel opioid receptor-like receptor of ORL1. It is resistant to enzymatic degradation and may have antinociceptive functions. Synonyms: Dynorphin (1-17) acetate; Dynorphin A (human, pig, rat, Bos taurus) acetate; Porcine dynorphin (1-17) acetate; L-Glutamine, L-tyrosylglycylglycyl-L-phenylalanyl-L-leucyl-L-arginyl-L-arginyl-L-isoleucyl-L-arginyl-L-prolyl-L-lysyl-L-leucyl-L-lysyl-L-tryptophyl-L-α-aspartyl-L-asparaginyl-, acetate; H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-Trp-Asp-Asn-Gln-OH.CH3CO2H. Grade: ≥95%. Molecular formula: C101H159N31O25. Mole weight: 2207.58. | |
| Dynorphin B 1-13 | Dynorphin B is a 13-residue opioid peptide, which is derived from the cleavage of prodynorphin and found widely distributed in the central nervous system. It acts as an opioid peptide and a κ-opioid receptor agonists. It has been implicated in antinociceptive functions. It has also been used to prime cardiogenesis in pluripotent embryonic stem cells. Synonyms: Prodynorphin (226-238) (human); Prodynorphin (228-240) (porcine); Rimorphin; Dynorphin B 1-13; H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Gln-Phe-Lys-Val-Val-Thr-OH; L-tyrosyl-glycyl-glycyl-L-phenylalanyl-L-leucyl-L-arginyl-L-arginyl-L-glutaminyl-L-phenylalanyl-L-lysyl-L-valyl-L-valyl-L-threonine. Grade: ≥95%. CAS No. 83335-41-5. Molecular formula: C74H115N21O17. Mole weight: 1570.84. | |
| Dysprosium trisodium bis(phosphate) | Dysprosium trisodium bis(phosphate). CAS No. 55859-88-6. Molecular formula: Na3Dy(PO4)2. Mole weight: 421.41. | |
| E-64 | E-64 is an irreversible and selective cysteine protease inhibitor with IC50 of 9 nM for papain. Uses: For research used only. Synonyms: L-trans-Epoxysuccinyl-Leu-4-guanidinobutylamide; Proteinase inhibitor E 64; 3-[[[(1S)-1-[[[4-[(aminoiminomethyl)amino]butyl]amino]carbonyl]-3-methylbutyl]amino]carbonyl]-(2S,3S)-oxiranecarboxylic acid; Thiol protease inhibitor; trans-Epoxysuccinyl-L-leucylamido-(4-guanidino)butane; 2-Oxiranecarboxylic acid, 3-[[[(1S)-1-[[[4-[(aminoiminomethyl)amino]butyl]amino]carbonyl]-3-methylbutyl]amino]carbonyl]-, (2S,3S)-; L-Trans-Epoxysuccinyl-Leu-agmatine. Grade: ≥99% by HPLC. CAS No. 66701-25-5. Molecular formula: C15H27N5O5. Mole weight: 357.41. | |
| (E)-6,6-dimethoxyhex-4-en-3-ol-[d5] | (E)-6,6-dimethoxyhex-4-en-3-ol-[d5]. Synonyms: (4E)-6,6-Dimethoxy(1,1,1,2,2-2H5)-4-hexen-3-ol; trans-4-Hydroxy-2-hexenal-5,5,6,6,6-d5 Dimethyl Acetal. Grade: 99% atom D. CAS No. 1219806-40-2. Molecular formula: C8H11D5O3. Mole weight: 165.24. | |
| Ebelactone A | It is produced by the strain of Streptomyces aburaviensis. It has the inhibitory effect on Esterases (IC50 is 0.56 μg/mL), Pancreatic lipase (IC50 is 0.003 μg/mL) and Cutinase on fungal cells. Synonyms: 2-Oxetanone, 4-(8-hydroxy-1,3,5,7,9-pentamethyl-6-oxo-3-undecenyl)-3-methyl-, (3S-(3-alpha,4-beta(1R*,3E,5S*,7R*,8S*,9S*)))-; (-)-ebelactone a. Grade: ≥98%. CAS No. 76808-16-7. Molecular formula: C20H34O4. Mole weight: 338.48. | |
| Ebenatide | Ebenatide is a long-acting glucagon-like peptide-1 recceptor agonist (GLP-1RA). Ebenatide is undergoing the clinical trial for the treatment of type 2 diabetes mellitus (T2DM). | |
| Echinocandin B | It is produced by the strain of Aspergillus rugulosus. Echinocandin can inhibit (1,3)-β-Glucan synthase, an essential component of the cell wall of susceptible fungi, and has anti-fungal activity against candida. Synonyms: NSC 287461; 5.1:6-anhydro{(4R,5R)-4,5-dihydroxy-N(2)-[(9Z,12Z)-octadeca-9,12-dienoyl]-L-ornithyl-L-threonyl-(4R)-4-hydroxy-L-prolyl-(4S)-4-hydroxy-4-(4-hydroxyphenyl)-L-threonyl-L-threonyl-(3S,4S)-3-hydroxy-4-methyl-L-proline}; Antibiotic A 22082; Antibiotic A 30912 factor A; Antibiotic A 30912A; Antibiotic SL 7810; Antibiotic SL 7810F. Grade: >95% by HPLC. CAS No. 54651-05-7. Molecular formula: C52H81N7O16. Mole weight: 1060.23. | |
| Echinomycin | It is produced by the strain of Streptomyces echinatus. It has the activity of anti-gram-positive bacteria and vaginal trichomonas, and also has the effect on influenza virus and sarcoma 180 cells in vitro. Synonyms: Quinomycin A; Levomycin; N,N'-((1R,4S,7R,11S,14R,17S,20R,24S)-11,24-diisopropyl-2,4,12,15,17,25-hexamethyl-27-(methylthio)-3,6,10,13,16,19,23,26-octaoxo-9,22-dioxa-28-thia-2,5,12,15,18,25-hexaazabicyclo[12.12.3]nonacosane-7,20-diyl)bis(quinoxaline-2-carboxamide); N-(2-Quinoxalinylcarbonyl)-O-[N-(2-quinoxalinylcarbonyl)-D-seryl-L-alanyl-3-mercapto-N,S-dimethylcysteinyl-N-methyl-L-valyl]-D-seryl-L-alanyl-N-methylcysteinyl-N-methyl-L-valine-(81)-lactone-cyclic(37)-thioether; Antibiotic A 654I; NSC 13502; NSC 526417. Grade: >99% by HPLC. CAS No. 512-64-1. Molecular formula: C51H64N12O12S2. Mole weight: 1101.25. | |
| Echinosporin | It is produced by the strain of Bacillus brevis Vm4, Streptomyces echinos porus MK-213. It has weak anti-gram-positive bacteria and tumor activity. Synonyms: (1S,4aS,5S,7aS)-1,4a,5,7a-Tetrahydro-5-hydroxy-8-oxo-1,5-(epoxymethano)cyclopenta[c]pyran-3-carboxamide; (-)-Echinosporin; Antibiotic XK 213; NSC 357683; XK 213; [1S-(1α,4aβ,5β,7aβ)]-1,4a,5,7a-Tetrahydro-5-hydroxy-8-oxo-1,5-(epoxymethano)cyclopenta[c]pyran-3-carboxamide. Grade: >98%. CAS No. 79127-35-8. Molecular formula: C10H9NO5. Mole weight: 223.18. | |
| Echistatin, α1 isoform | Echistatin, α1 isoform is a potent and irreversible αVβ3 integrin antagonist (Ki = 0.27 nM). It exhibits inhibitory activity for bone reabsorption (IC50 = 0.1 nM) and prevents ADP-induced platelet aggregation by inhibiting glycoprotein IIb/IIIa (GpIIb/IIIa, αIIbβ3) receptors (IC50 = 30 nM) in vitro. Synonyms: H-Glu-Cys(1)-Glu-Ser-Gly-Pro-Cys(2)-Cys(3)-Arg-Asn-Cys(1)-Lys-Phe-Leu-Lys-Glu-Gly-Thr-Ile-Cys(4)-Lys-Arg-Ala-Arg-Gly-Asp-Asp-Met-Asp-Asp-Tyr-Cys(2)-Asn-Gly-Lys-Thr-Cys(3)-Asp-Cys(4)-Pro-Arg-Asn-Pro-His-Lys-Gly-Pro-Ala-Thr-OH; L-alpha-glutamyl-L-cysteinyl-L-alpha-glutamyl-L-seryl-glycyl-L-prolyl-L-cysteinyl-L-cysteinyl-L-arginyl-L-asparagyl-L-cysteinyl-L-lysyl-L-phenylalanyl-L-leucyl-L-lysyl-L-alpha-glutamyl-glycyl-L-threonyl-L-isoleucyl-L-cysteinyl-L-lysyl-L-arginyl-L-alanyl-L-arginyl-glycyl-L-alpha-aspartyl-L-alpha-aspartyl-L-methionyl-L-alpha-aspartyl-L-alpha-aspartyl-L-tyrosyl-L-cysteinyl-L-asparagyl-glycyl-L-lysyl-L-threonyl-L-cysteinyl-L-alpha-aspartyl-L-cysteinyl-L-prolyl-L-arginyl-L-asparagyl-L-prolyl-L-histidyl-L-lysyl-glycyl-L-prolyl-L-alanyl-L-threonine (2->11),(7->32),(8->37),(20->39)-tetrakis(disulfide). Grade: >98%. CAS No. 154303-05-6. Molecular formula: C217H341N71O74S9. Mole weight: 5417.05. | |
| EDA-ADP - Biotin | EDA-ADP - Biotin is a precious compound is a formidable instrument used in deciphering the enigmatic rapport forged between ATP-binding proteins. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-Adenosine-5'-diphosphate - Biotin. Grade: ≥ 95 % by HPLC. Molecular formula: C23H35N9O13P2S. Mole weight: 739.59. | |
| EDA-AppNHp (EDA-AMPPNP) - Biotin | The Biotin-derived form of EDA-AppNHp (EDA-AMPPNP), which could be used in biological studies. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-Adenosine-5'-[(β,γ)-imido] triphosphate- Biotin, Triethylammonium salt. Grade: ≥ 95 % by HPLC. Molecular formula: C23H37N10O15P3S (free acid). Mole weight: 818.58 (free acid). | |
| EDA-ATP - Biotin | EDA-ATP - Biotin is a pivotal component extensively operating as a labeling catalyst for nucleic acids and proteins, enabling their identification and visualization. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-adenosine-5'-triphosphate - Biotin, Triethylammonium salt. Grade: ≥ 95 % by HPLC. Molecular formula: C23H36N9O16P3S (free acid). Mole weight: 819.57 (free acid). | |
| EDA-ATPγS - Biotin | EDA-ATPγS - Biotin is a remarkable compound, serving as an exquisite tool extensively employed in the realm of investigating intricate protein-protein interactions. With EDA-ATPγS acting as a nucleotide analog and Biotin acting as a labeling moiety, this innovative formulation contributes significantly to the research of ATPγS-binding proteins. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-adenosine-5'-(γ-thio)-triphosphate - Biotin, Triethylammonium salt. Grade: ≥ 90 % by HPLC, contains approx. 5 % EDA-ADP-Biotin. Molecular formula: C23H36N9O15P3S2(free acid). Mole weight: 835.64 (free acid). | |
| EDA-GppNHp (EDA-GMPPNP) - Biotin | EDA-GppNHp is a derivative compound conjugated with biotin known also as EDA-GMPPNP, widely employed in the biomedical field. Its utilization primarily revolves around deciphering intricate cellular mechanisms, particularly those associated with G protein signaling pathways. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-Guanosine-5'-[(β,γ)-imido] triphosphate - Biotin, Triethylammonium salt. Grade: ≥ 95 % by HPLC. Molecular formula: C23H37N10O16P3S (free acid). Mole weight: 834.58 (free acid). | |
| EDA-GTP - Biotin | EDA-GTP-Biotin, a biochemical compound utilized in the biomedical sector, delves into biological processes linked to GTP binding proteins in research applications. As a potent catalyst, it scrutinizes signal transduction pathways and proves advantageous in identifying GTP binding sites on proteins. The compound, used as a research tool, sheds light on ailments such as cancer, Alzheimer's, and Huntington's disease. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-guanosine-5'-triphosphate - Biotin, Triethylammonium salt. Grade: ≥ 95 % by HPLC. Molecular formula: C23H36N9O17P3S (free acid). Mole weight: 835.57 (free acid). | |
| EDA-GTPγS - Biotin | EDA-GTPγS - Biotin, a research instrument utilized in the biomedical sector, explores the workings of G protein-coupled receptors (GPCRs) and their communication with signaling proteins. Coupled with biotin, it permits effortless identification and refinement. The pharmaceutical industry primarily employs it in drug discovery to sift through compounds that influence GPCR activity. The research tool additionally delves into cancer and cardiovascular diseases. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-guanosine-5'-(γ-thio)-triphosphate - Biotin, Triethylammonium salt. Grade: ≥ 90 % by HPLC, contains approx. 5 % EDA-GDP-Biotin. Molecular formula: C23H36N9O16P3S2(free acid). Mole weight: 851.63 (free acid). | |
| EDA-m7GDP - Biotin | EDA-m7GDP - Biotin is a compound widely used in Biomedicine. This compound is utilized to study RNA cap structure. EDA-m7GDP - Biotin works as a probe that selectively binds to cap structures on RNA molecules. Researchers utilize this compound in experiments to isolate and identify proteins that interact with the RNA cap structure. This compound is applied in a range of studies related to viral infections and cancer. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-N7-methyl-guanosine-5'-diphosphate - Biotin, Triethylammonium salt. Grade: ≥ 95 % by HPLC. Molecular formula: C24H37N9O14P2S (free acid). Mole weight: 769.61 (free acid). | |
| EDA-m7GTP - Biotin | EDA-m7GTP - Biotin is a powerful tool in the biomedical industry used for labeling and detection of RNA transcripts. It is specifically designed for studying cap-dependent translation initiation mechanism and mRNA metabolism. With its biotin moiety, it enables precise and efficient detection of m7GTP-bound proteins, RNA and their associated processes, contributing to a deeper research of various diseases and potential drug targets. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-N7-methyl-guanosine-5'-triphosphate - Biotin, Triethylammonium salt. Grade: ≥ 95 % by HPLC. Molecular formula: C24H38N9O17P3S (free acid). Mole weight: 849.59 (free acid). | |
| Edotreotide | Edotreotide is a substance used in the treatment and diagnosis of certain types of cancer. Synonyms: L-Cysteinamide, N-[2-[4,7,10-tris(carboxymethyl)-1,4,7,10-tetraazacyclododec-1-yl]acetyl]-D-phenylalanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2→7)-disulfide; L-Cysteinamide, N-[[4,7,10-tris(carboxymethyl)-1,4,7,10-tetraazacyclododec-1-yl]acetyl]-D-phenylalanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2→7)-disulfide; (DOTA-D-Phe1,Tyr3)octreotide; DOTATOC; SDZ-SMT 487; SMT 487; SomaKit TOC; DOTA-(Tyr3)-Octreotide; SMT-487; SMT487; DOTA-d-Phe1-Tyr3-octreotide; DOTA-TOC. Grade: 98%. CAS No. 204318-14-9. Molecular formula: C65H92N14O18S2. Mole weight: 1421.64. | |
| Eflornithine | Eflornithine is a difluoromethylated ornithine compound with antineoplastic activity. Eflornithine irreversibly inhibits ornithine decarboxylase, an enzyme required for polyamine biosynthesis, thereby inhibiting the formation and proliferation of tumor cells. Polyamines are involved in nucleosome oligomerization and DNA conformation, creating a chromatin environment that stimulates neoplastic transformation of cells. This agent has been shown to induce apoptosis in leiomyoma cells. Synonyms: Ornithine, 2-(difluoromethyl)-; 2-(Difluoromethyl)ornithine; 2-(Difluoromethyl)-DL-ornithine; DL-2-(Difluoromethyl)ornithine; DL-α-(Difluoromethyl)ornithine; DFMO; DFMO (growth regulator); Difluromethylornithine; Elfornithine; MDL 71782; MDL 71782A; Ornidyl; RFI 71782; RMI 71782; α,δ-Diamino-α-(difluoromethyl)valeric acid; α-(Difluoromethyl)-DL-ornithine; α-(Difluoromethyl)ornithine. Grade: ≥95%. CAS No. 70052-12-9. Molecular formula: C6H12F2N2O2. Mole weight: 182.17. | |
| Eflornithine hydrochloride, hydrate | Eflornithine hydrochloride, hydrate is a drug found to be effective in the treatment of facial hirsutism. It is a "suicide inhibitor," irreversibly binding to Ornithine Decarboxylase (ODC) and preventing the natural substrate ornithine from accessing the active site. It is an irreversible inhibitor of ornithine decarboxylase that suppresses polyamine biosynthesis. It displays antiangiogenic and cytostatic effects in tumor cells but must be used in combination with other chemotherapeutic agents to negate compensatory increases in polyamine content through alternate synthesis pathways. It also demonstrates antiparasitic activity in a model of C. parvum infection. Synonyms: DFMO hydrochloride hydrate; MDL-71782 hydrochloride hydrate; RMI-71782 hydrochloride hydrate; MDL 71782 hydrochloride hydrate; RMI 71782 hydrochloride hydrate; MDL71782 hydrochloride hydrate; RMI71782 hydrochloride hydrate; α-difluoromethylornithine hydrochloride hydrate; Vaniqa hydrochloride hydrate. Grade: 98%. CAS No. 96020-91-6. Molecular formula: C6H15ClF2N2O3. Mole weight: 236.64. | |
| Efpeglenatide | Efpeglenatide is a long-acting glucagon-like peptide-1 receptor agonist (GLP-1RA). Efpeglenatide has been developed as an injection for type 2 diabetes mellitus (T2DM). Synonyms: efpeg. CAS No. 1296200-77-5. | |
| EGF Receptor (985-996) (human) | EGF Receptor (985-996) (human) exists on the cell surface and is activated by the binding of its specific ligands. EGFR belongs to the tyrosine kinase receptor (RTK) ErbB family. Synonyms: L-Glutamine, L-α-aspartyl-L-valyl-L-valyl-L-α-aspartyl-L-alanyl-L-α-aspartyl-L-α-glutamyl-L-tyrosyl-L-leucyl-L-isoleucyl-L-prolyl-; L-Glutamine, N2-[1-[N-[N-[N-[N-[N-[N-[N-[N-(N-L-α-aspartyl-L-valyl)-L-valyl]-L-α-aspartyl]-L-alanyl]-L-α-aspartyl]-L-α-glutamyl]-L-tyrosyl]-L-leucyl]-L-isoleucyl]-L-prolyl]-; L-α-Aspartyl-L-valyl-L-valyl-L-α-aspartyl-L-alanyl-L-α-aspartyl-L-α-glutamyl-L-tyrosyl-L-leucyl-L-isoleucyl-L-prolyl-L-glutamine; H-Asp-Val-Val-Asp-Ala-Asp-Glu-Tyr-Leu-Ile-Pro-Gln-OH; Epidermal Growth Factor Receptor Peptide. Grade: ≥95%. CAS No. 96249-43-3. Molecular formula: C61H93N13O23. Mole weight: 1376.46. | |
| ELA-14 (human) | ELA-14 (human) is a potent apelin (APJ) receptor agonist (Ki = 0.93 nM) stimulating Gαi1 pathway and β-arrestin-2 recruitment. It decreases arterial pressure in rat hearts. Synonyms: Elabela (19-32). CAS No. 1886973-05-2. Molecular formula: C75H119N25O17S2. Mole weight: 1707.03. | |
| ELA-14 (human) acetate | ELA-14 (human) acetate is a potent apelin (APJ) receptor agonist (Ki = 0.93 nM) stimulating the Gαi1 pathway and β-arrestin-2 recruitment. It decreases arterial pressure in rat hearts. Synonyms: H-Pyr-Arg-Arg-Cys-Met-Pro-Leu-His-Ser-Arg-Val-Pro-Phe-Pro-OH.CH3CO2H; L-pyroglutamyl-L-arginyl-L-arginyl-L-cysteinyl-L-methionyl-L-prolyl-L-leucyl-L-histidyl-L-seryl-L-arginyl-L-valyl-L-prolyl-L-phenylalanyl-L-proline acetate; Elabela (19-32) acetate; ELA (19-32) (human) acetate. Grade: ≥95%. Molecular formula: C77H123N25O19S2. Mole weight: 1767.09. | |
| Elaiophylin | It is produced by the strain of Streptomyces melanosporofacien. It has the activity of anti-gram-positive bacteria, mycobacterium and protozoa, and can be used as insect repellent and growth promoter for ruminants. Elaiophylin is an autophagy inhibitor, which exerts antitumor activity as a single agent in ovarian cancer cells. Synonyms: Azalomycin B; Salbomycin; Azalomycin B; Antibiotic 5001B; Antibiotic 56-62; Elaiofilin. Grade: ≥95%. CAS No. 37318-06-2. Molecular formula: C54H88O18. Mole weight: 1025.26. | |
| Elasnin | Elasnin is isolated from certain strains of Streptomyces. Elasnin is a reversible inhibitor of elastase with IC50 values of 1.3 and 30 μg/ml for human granulocyte and pancreatic enzymes, respectively. It inhibits human leukocyte elastase, porcine pancreatic elastase, and chymotrypsin with Ki values of 93, 69 and 224 μM, respectively. Synonyms: 3,5-dibutyl-2-hydroxy-6-(6-oxoundecan-5-yl)-4H-pyran-4-one; 3,?5-Dibutyl-6-(1-butyl-2-oxoheptyl)?-4-hydroxy-2H-pyran-2-one. Grade: ≥98%. CAS No. 68112-21-0. Molecular formula: C24H40O4. Mole weight: 392.57. | |
| Eledoisin | Eledoisin is an undecapeptide of mollusk origin and it belongs to the tachykinin family of neuropeptides. It was first isolated from the posterior salivary glands of two mollusk species Eledone muschata and Eledone aldovandi. Eledoisin has the amino acid sequence pGlu-Pro-Ser-Lys-Asp-Ala-Phe-Ile-Gly-Leu-Met-NH2. It is the Potent natural tachykinin receptor ligand. Uses: Neurotransmitter agents. Synonyms: Eledone peptide; Eledoisinum; 5-oxo-L-prolyl-L-prolyl-L-seryl-L-lysyl-L-α-aspartyl-L-alanyl-L-phenylalanyl-L-isoleucylglycyl-L-leucyl-L-methioninamide. Grade: >98%. CAS No. 69-25-0. Molecular formula: C54H85N13O15S. Mole weight: 1188.41. | |
| Eledoisin Related Peptide | Eledoisin-Related Peptide, a substance P analogue, is a tachykinin receptor ligand. Synonyms: Eledoisin-Related Peptide; Eledoisin RP; H-Lys-Phe-Ile-Gly-Leu-Met-NH2; L-lysyl-L-phenylalanyl-L-isoleucyl-glycyl-L-leucyl-L-methioninamide; (S)-2,6-diamino-N-((5S,8S,14S,17S)-14-sec-butyl-5-carbamoyl-8-isobutyl-7,10,13,16-tetraoxo-18-phenyl-2-thia-6,9,12,15-tetraazaoctadecan-17-yl)hexanamide; Lpiglm. Grade: ≥95%. CAS No. 2990-43-4. Molecular formula: C34H58N8O6S. Mole weight: 706.94. | |
| Eledoisin Related Peptide 2TFA | Eledoisin Related Peptide 2TFA, a substance P analogue, is a tachykinin receptor ligand. Synonyms: H-Lys-Phe-Ile-Gly-Leu-Met-NH2.2TFA; L-lysyl-L-phenylalanyl-L-isoleucyl-glycyl-L-leucyl-L-methioninamide trifluoroacetic acid. Grade: ≥95%. CAS No. 2918768-25-7. Molecular formula: C34H58N8O6S.2C2HF3O2. Mole weight: 934.99. | |
| Eledoisin trifluoroacetate | Eledoisin was first isolated from the posterior salivary glands of two mollusk species Eledone muschata and Eledone aldovandi. It is a potent natural tachykinin receptor ligand, and a potent vasodilator that increases capillary permeability. Synonyms: H-Pyr-Pro-Ser-Lys-Asp-Ala-Phe-Ile-Gly-Leu-Met-NH2.TFA; L-pyroglutamyl-L-prolyl-L-seryl-L-lysyl-L-alpha-aspartyl-L-alanyl-L-phenylalanyl-L-isoleucyl-glycyl-L-leucyl-L-methioninamide trifluoroacetic acid; Eledoisin, mono(trifluoroacetate) (salt); 5-Oxo-L-prolyl-L-prolyl-L-seryl-L-lysyl-L-aspartyl-L-alanyl-L-phenylalanyl-L-isoleucylglycyl-L-leucyl-L-methioninamide trifluoroacetate; Eledoisin, trifluoroacetate (1:1). Grade: ≥95%. CAS No. 10129-92-7. Molecular formula: C54H85N13O15S.C2HF3O2. Mole weight: 1302.42. | |
| Elsamitrucin | Elsamitrucin is produced by the strain of Actinomycetes J904-21. It has strong anti-tumor activity of mouse tumor cells such as leukemia P388, L1210 and melanoma B16, and its anti-tumor activity is 10-30 times stronger than Chartreusin. Uses: Antibiotics, antineoplastic. Synonyms: Elsamicin A. Grade: >95%. CAS No. 97068-30-9. Molecular formula: C33H35NO13. Mole weight: 653.63. | |
| Elsinochrome A | It is produced by the strain of Elsinoe annonae, Sphaceloma randii. It's the same as Hypericin, it has photodynamic activity and inhibits protein kinase C activity. Synonyms: (1r,2r)-1,2-diacetyl-4,11-dihydroxy-3,7,8,12-tetramethoxy-1,2-dihydrobenzo[ghi]perylene-5,10-dione; 1alpha,2beta-Diacetyl-1,2-dihydro-5,10-dihydroxy-3,7,8,12-tetramethoxybenzo[ghi]perylene-4,11-dione; Benzo(ghi)perylene-4,11-dione, 1,2-diacetyl-1,2-dihydro-5,10-dihydroxy-3,7,8,12-tetramethoxy-, trans-. Grade: ≥98%. CAS No. 24568-67-0. Molecular formula: C30H24O10. Mole weight: 544.51. | |
| (E)-methyl 4-(benzyloxy)-2-((dimethylamino)methyleneamino)-5-methoxybenzoate | (E)-methyl 4-(benzyloxy)-2-((dimethylamino)methyleneamino)-5-methoxybenzoate. CAS No. 263149-09-3. Molecular formula: C19H22N2O4. Mole weight: 342.4. | |
| Emodepside | Emodepside, also known as PF 1022-221, a semisynthetic derivative of PF1022A, is efficacious against a variety of gastrointestinal nematodes and used as an anthelmintic drug with broad-spectrum anthelmintic activity. Emodepside is an octapeptide drug that has been approved for use in cats. Synonyms: BAY 44-4400; BAY44-4400; BAY-44-4400; BAY 444400; BAY444400; BAY-444400; cyclo[N(Me)Leu-D-OAla-N(Me)Leu-D-OPhe(morpholino)-N(Me)Leu-D-OAla-N(Me)Leu-D-OPhe(morpholino)]; cyclo[N-methyl-L-leucyl-N-oxa-D-alanyl-N-methyl-L-leucyl-N-oxa-4-morpholino-D-phenylalanyl-N-methyl-L-leucyl-N-oxa-D-alanyl-N-methyl-L-leucyl-N-oxa-4-morpholino-D-phenylalanyl]. Grade: ≥95%. CAS No. 155030-63-0. Molecular formula: C60H90N6O14. Mole weight: 1119.39. | |
| endo-BCN-PEG4-Biotin | endo-BCN-PEG4-Biotin. Molecular formula: C31H50N4O8S. Mole weight: 638.8. | |
| Endomorphin 1 | Endomorphin 1 is a high affinity (Ki = 360 pM) and highly selective agonist of theμ-opioid receptor with 4000- and 15000-fold preference over δ and κ respectively and displays reasonable affinities for kappa3 binding sites, with Ki value between 20 and 30 nM. Uses: Analgesics, opioid. Synonyms: L-tyrosyl-L-prolyl-L-tryptophyl-L-phenylalaninamide. CAS No. 189388-22-5. Molecular formula: C34H38N6O5. Mole weight: 610.7. | |
| Endomorphin 2 | Endomorphin 2, an andogenous peptide, has high affinity and specificity for the μ-opioid receptor and displays reasonable affinities for kappa3 binding sites, with Ki value between 20 and 30 nM. Uses: Analgesics, opioid. Synonyms: H-Tyr-Pro-Phe-Phe-NH2; L-tyrosyl-L-prolyl-L-phenylalanyl-L-phenylalaninamide; (2S)-1-[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]-N-[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]pyrrolidine-2-carboxamide. Grade: >95%. CAS No. 141801-26-5. Molecular formula: C32H37N5O5. Mole weight: 571.7. | |
| Endothelin 1 (swine, human) | Endothelin 1 (swine, human), a vasoconstrictor increased in plasma and explants of patients with uterine leiomyomas, is a synthetic peptide with the sequence of human and swine Endothelin 1 and acts through two types of receptors ETA and ETB. Synonyms: Endothelin 1 swine, human; Endothelin 1; L-cysteinyl-L-seryl-L-cysteinyl-L-seryl-L-seryl-L-leucyl-L-methionyl-L-alpha-aspartyl-L-lysyl-L-alpha-glutamyl-L-cysteinyl-L-valyl-L-tyrosyl-L-phenylalanyl-L-cysteinyl-L-histidyl-L-leucyl-L-alpha-aspartyl-L-isoleucyl-L-isoleucyl-L-tryptophan (1->15),(3->11)-bis(disulfide); H-Cys(1)-Ser-Cys(2)-Ser-Ser-Leu-Met-Asp-Lys-Glu-Cys(2)-Val-Tyr-Phe-Cys(1)-His-Leu-Asp-Ile-Ile-Trp-OH. Grade: 95%. CAS No. 117399-94-7. Molecular formula: C109H159N25O32S5. Mole weight: 2491.9. | |
| Endothelin-2, human | Endothelin 2 is a ligand for the endothelin (ET) receptors and a potent vasoconstrictor mainly found in the kidney and intestine. Uses: Vasoconstrictor. Synonyms: Endothelin-2 (human, canine); Human endothelin-2; ET-2 (human); H-Cys(1)-Ser-Cys(2)-Ser-Ser-Trp-Leu-Asp-Lys-Glu-Cys(2)-Val-Tyr-Phe-Cys(1)-His-Leu-Asp-Ile-Ile-Trp-OH; L-cysteinyl-L-seryl-L-cysteinyl-L-seryl-L-seryl-L-tryptophyl-L-leucyl-L-alpha-aspartyl-L-lysyl-L-alpha-glutamyl-L-cysteinyl-L-valyl-L-tyrosyl-L-phenylalanyl-L-cysteinyl-L-histidyl-L-leucyl-L-alpha-aspartyl-L-isoleucyl-L-isoleucyl-L-tryptophan (1->15),(3->11)-bis(disulfide). Grade: ≥95%. CAS No. 123562-20-9. Molecular formula: C115H160N26O32S4. Mole weight: 2546.92. | |
| Endothelin-3, human, mouse, rabbit, rat | Endothelin 3 is a ligand of the endothelin (ET) receptors and a potent vasoconstrictor. Endothelin 3 increases blood pressure in spontaneously hypertensive and normotensive rats, and promotes migration and adhesion of enteric neural crest cells (ENCCs) to the embryonic gut in mice via interaction with ETB. Uses: Vasoconstrictor. Synonyms: Endothelin 3 (Rat,Human); ET-3 (Rat,Human); H-Cys(1)-Thr-Cys(2)-Phe-Thr-Tyr-Lys-Asp-Lys-Glu-Cys(2)-Val-Tyr-Tyr-Cys(1)-His-Leu-Asp-Ile-Ile-Trp-OH; L-cysteinyl-L-threonyl-L-cysteinyl-L-phenylalanyl-L-threonyl-L-tyrosyl-L-lysyl-L-alpha-aspartyl-L-lysyl-L-alpha-glutamyl-L-cysteinyl-L-valyl-L-tyrosyl-L-tyrosyl-L-cysteinyl-L-histidyl-L-leucyl-L-alpha-aspartyl-L-isoleucyl-L-isoleucyl-L-tryptophan (1->15),(3->11)-bis(disulfide). Grade: ≥97% by HPLC. CAS No. 117399-93-6. Molecular formula: C121H168N26O33S4. Mole weight: 2643.04. | |
| Endothelin-3, human, mouse, rabbit, rat TFA | Endothelin-3 is a peptide vasoconstricter and a ligand of the endothelin (ET) receptors ETA and ETB (Kbs = 1.05 and 1.49, respectively). It binds to G-protein-linked transmembrane receptors, ET-RA and ET-RB. Synonyms: Endothelin 3 (Rat,Human) (TFA); ET-3 (Rat,Human) (TFA); H-Cys(1)-Thr-Cys(2)-Phe-Thr-Tyr-Lys-Asp-Lys-Glu-Cys(2)-Val-Tyr-Tyr-Cys(1)-His-Leu-Asp-Ile-Ile-Trp-OH.TFA; L-cysteinyl-L-threonyl-L-cysteinyl-L-phenylalanyl-L-threonyl-L-tyrosyl-L-lysyl-L-alpha-aspartyl-L-lysyl-L-alpha-glutamyl-L-cysteinyl-L-valyl-L-tyrosyl-L-tyrosyl-L-cysteinyl-L-histidyl-L-leucyl-L-alpha-aspartyl-L-isoleucyl-L-isoleucyl-L-tryptophan (1->15),(3->11)-bis(disulfide) trifluoroacetic acid; Endothelin-3 (human, rat) trifluoroacetate salt. Grade: ≥95%. Molecular formula: C121H168N26O33S4.C2HF3O2. Mole weight: 2757.07. | |
| Endotoxin inhibitor | Endotoxin inhibitor bears a structural resemblance to the peptide antibiotic and endotoxin inhibitor polymyxin B. It could be of use as an adjuvant for antibiotic therapy. Synonyms: H-Lys-Thr-Lys-Cys-Lys-Phe-Leu-Lys-Lys-Cys-OH. CAS No. 147396-10-9. Molecular formula: C55H97N15O12S2. Mole weight: 1224.58. | |
| Enduracidin | It is produced by the strain of Streptomyces fungicidicus. Enramycin is a polypeptide antibiotic, and it has anti-gram-positive bacteria and mycobacterium activity. Enramycin is composed of two different compounds: Enramycin A and enramycin B. Synonyms: Enramycin; Enramycin Premix; Enramicina; Enramycinum; Enradin. Grade: >95%. CAS No. 11115-82-5. Molecular formula: C107H138Cl2N26O31 (Enramycin A); C108H140Cl2N26O31 (Enramycin B). Mole weight: 2550.21 (Enramycin A); 2564.24 (Enramycin B). | |
| Enduracidin A | It is produced by the strain of Streptomyces fungicidicus. It has anti-gram-positive bacteria and mycobacterium activity. Synonyms: 1-Oxa-4,7,10,13,16,19,22,25,28,31,34,37,40,43,46-pentadecaazacyclononatetracontane, enduracidin A derivative; [1(Z,E),10(R),15(R)]-N-(10-Methyl-1-oxo-2,4-undecadienyl)-L-α-aspartyl-L-threonyl-D-2-(4-hydroxyphenyl)glycyl-D-ornithyl-D-allothreonyl-L-2-(4-hydroxyphenyl)glycyl-D-2-(4-hydroxyphenyl)glycyl-L-allothreonyl-N5-(aminocarbonyl)-L-ornithyl-3-(2-amino-4,5-dihydro-1H-imidazol-4-yl)-D-alanyl-L-2-(4-hydroxyphenyl)glycyl-D-seryl-L-2-(3,5-dichloro-4-hydroxyphenyl)glycylglycyl-3-(2-amino-4,5-dihydro-1H-imidazol-4-yl)-L-alanyl-D-alanyl-L-2-(4-hydroxyphenyl)glycine 1-lactone; Enramycin A. Grade: >95%. CAS No. 34438-27-2. Molecular formula: C107H138Cl2N26O31. Mole weight: 2355.30. | |
| Enduracidin B | It is produced by the strain of Streptomyces fungicidicus. It has anti-gram-positive bacteria and mycobacterium activity. Synonyms: Enramycin B. Grade: 85%. CAS No. 34304-21-7. Molecular formula: C108H140Cl2N26O31. Mole weight: 2369.32. | |
| Enfumafungin | Enfumafungin is a triterpene glycoside and hemiacetal isolated from a fermentation of Hormonema sp. Enfumafungin is an antifungal agent that acts on fungal cell walls as an inhibitor of (1,3)-beta-D-glucan synthase. It is specific for yeast and fungi (excluding Cryptococcus) and does not inhibit the growth of Bacillus subtilis. Synonyms: 4H-1,4a-Propano-2H-phenanthro[1,2-c]pyran-7-carboxylic acid, 14-(acetyloxy)-8-[(1R)-1,2-dimethylpropyl]-15-(β-D-glucopyranosyloxy)-1,6,6a,7,8,9,10,10a,10b,11,12,12a-dodecahydro-4-hydroxy-1,6a,8,10a-tetramethyl-, (1S,4aR,6aS,7R,8R,10aR,10bR,12aS,14R,15R)-. Grade: ≥98%. CAS No. 260979-95-1. Molecular formula: C38H60O12. Mole weight: 708.88. | |
| Enfuvirtide | Enfuvirtide is a biomimetic peptide of HIV-1 fusion inhibitor with CD4+ cells and it is used to patients with multi-drug resistant HIV. Enfuvirtide binds to gp41 preventing the creation of an entry pore for the HIV-1 virus. Synonyms: N-Acetyl-L-tyrosyl-L-threonyl-L-seryl-L-leucyl-L-isoleucyl-L-histidyl-L-seryl-L-leucyl-L-isoleucyl-L-α-glutamyl-L-α-glutamyl-L-seryl-L-glutaminyl-L-asparaginyl-L-glutaminyl-L-glutaminyl-L-α-glutamyl-L-lysyl-L-asparaginyl-L-α-glutamyl-L-glutaminyl-L-α-glutamyl-L-leucyl-L-leucyl-L-α-glutamyl-L-leucyl-L-α-aspartyl-L-lysyl-L-tryptophyl-L-alanyl-L-seryl-L-leucyl-L-tryptophyl-L-asparaginyl-L-tryptophyl-L-phenylalaninamide; DP 178; ENF; Fuzeon; GP 41-127-162AA; Pentafuside; T 20; T 20 (peptide); Ac-Tyr-Thr-Ser-Leu-Ile-His-Ser-Leu-Ile-Glu-Glu-Ser-Gln-Asn-Gln-Gln-Glu-Lys-Asn-Glu-Gln-Glu-Leu-Leu-Glu-Leu-Asp-Lys-Trp-Ala-Ser-Leu-Trp-Asn-Trp-Phe-NH2. Grade: ≥98%. CAS No. 159519-65-0. Molecular formula: C204H301N51O64. Mole weight: 4491.88. | |
| Enniatin A | It is produced by the strain of Fusarium orthoceras var. enniatinum. It has insecticidal and antifungal activity. Synonyms: Cyclo((2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-isoleucyl-(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-isoleucyl-(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-isoleucyl); N-Methylcyclo(L-Ile-D-Hmb-N-methyl-L-Ile-D-Hmb-N-methyl-L-Ile-D-Hmb-); Lateritin I. Grade: >99% by HPLC. CAS No. 2503-13-1. Molecular formula: C36H63N3O9. Mole weight: 681.90. | |
| Enniatin A1 | A family of depsipeptide ionophores, produced by several fusarium species. It has antibiotic properties. Enniatin A1 is one of four major analogues in the enniatin complex. Enniatin A1 has been found to induce apoptosis in cancer cells, decrease the activation of the cell proliferation kinase, ERK (p44/p42) and inhibit TNF-α-induced NF-κB activation. Synonyms: 2-(N-Methyl-L-valine)enniatin A; Cyclo(D-α-hydroxyisovaleryl-N-methyl-L-isoleucyl-D-α-hydroxyisovaleryl-N-methyl-L-isoleucyl-D-α-hydroxyisovaleryl-N-methyl-L-valyl); cyclo[N-methyl-L-isoleucyl-N-oxa-D-valyl-N-methyl-L-isoleucyl-N-oxa-D-valyl-N-methyl-L-valyl-N-oxa-D-valyl]; Cyclo((2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-isoleucyl-(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-isoleucyl-(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-valyl). Grade: >99% by HPLC. CAS No. 4530-21-6. Molecular formula: C35H61N3O9. Mole weight: 667.87. | |
| Enniatin complex | A complex of depsipeptides produced by several fusarium species. the complex contains 4 major components: A, A1, B and B1 together with minor amounts of enniatins C, D, E and F. Synonyms: cyclo[N-methyl-L-isoleucyl-N-oxa-D-valyl-N-methyl-L-isoleucyl-N-oxa-D-valyl-N-methyl-L-isoleucyl-N-oxa-D-valyl] compound with cyclo[N-methyl-L-isoleucyl-N-oxa-D-valyl-N-methyl-L-isoleucyl-N-oxa-D-valyl-N-methyl-L-valyl-N-oxa-L-valyl] compound with cyclo[N-methyl-L-isoleucyl-N-oxa-D-valyl-N-methyl-L-valyl-N-oxa-D-valyl-N-methyl-L-valyl-N-oxa-D-valyl] compound with cyclo[N-oxa-D-valyl-N-methyl-L-valyl-N-oxa-D-valyl-N-methyl-L-valyl-N-oxa-D-valyl-N-methyl-L-valyl]. Grade: >95% by HPLC. CAS No. 11113-62-5. Molecular formula: C36H63N3O9.C35H61N3O9.C34H59N3O9.C33H57N3O9. Mole weight: 2643.46. | |
| Enopeptin A | It is produced by the strain of Streptomyces griseus. It has activity against gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA), and it also has antibacterial activity of phage. Synonyms: N-[[(2E,4E,6E,8E,10E)-12-(2-Hydroxy-5-oxo-1-cyclopentenylamino)-1,12-dioxo-2,4,6,8,10-dodecapentenyl]-L-Phe-]cyclo[L-Ser*-L-Pro-N-methyl-L-Ala-L-Ala-4β-methyl-L-Pro-]; [trans-(all-E)]-1-[N-[N-[1-[N-[N-[12-[(2-Hydroxy-5-oxo-1-cyclopenten-1-yl)amino]-1,12-dioxo-2,4,6,8,10-dodecapentaenyl]-L-phenylalanyl]-L-seryl]-L-prolyl]-N-methyl-L-alanyl]-L-alanyl]-4-methyl-L-proline ξ-lactone; Enopeptin II; NSC657143. Grade: >95% by HPLC. CAS No. 139601-96-0. Molecular formula: C47H57N7O11. Mole weight: 896.00. | |
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