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Flurbiprofen
Flurbiprofen is a nonsteroidal anti-inflammatory drug (NSAID) belonging to the propionic acid class. It exerts analgesic, anti-inflammatory, and antipyretic effects by reversibly inhibiting cyclooxygenase (COX) enzymes, thereby reducing prostaglandin synthesis. Clinically, it is used to manage pain and inflammation in conditions such as rheumatoid arthritis, osteoarthritis, and postoperative discomfort. Uses: Anti-inflammatory agents, non-steroidal. Synonyms: 2-Fluoro-α-methyl[1,1'-biphenyl]-4-acetic acid; (±)-Flurbiprofen; 2-(2-Fluoro-1,1'-biphenyl-4-yl)propanoic acid; 2-(2-Fluoro-4-biphenyl)propionic acid; 2-(2-Fluoro-4-biphenylyl)propanoic acid; 2-(2-Fluoro-4-biphenylyl)propionic acid; 2-Fluoro-α-methyl-4-biphenylacetic acid; 2-Fluoro-α-methyl-4-diphenylacetic acid; 3-Fluoro-4-phenylhydratropic acid; Adfeed; Ansaid; Antadys; BTS 18322; Cebutid; dl-2-(2-Fluoro-4-biphenylyl)propionic acid; dl-Flurbiprofen; Flugalin; Flurbifen; Fluribiprofen; Fluroben; Flurofen; FP 70; FP-A; Froben; rac-Flurbiprofen; Racemic flurbiprofen; Stayban; Synalgo; U 27182; Urbifen; Zepolas. Grade: >98%. CAS No. 5104-49-4. Molecular formula: C15H13FO2. Mole weight: 244.26.
(±)-Flurbiprofen-[d5]
(±)-Flurbiprofen-[d5] is the labelled analogue of (±)-Flurbiprofen, which could be used as an analgesic and anti-inflammatory agent. Synonyms: (+/-)-Flurbiprofen D5; 2-Fluoro-α-methyl-[1,1'-biphenyl]-4-acetic-d5 Acid; 3-Fluoro-4-phenylhydratropic-d5 Acid; Flurbiprofen-d5; 2-Fluoro-α-methyl-4-diphenylacetic-d5 Acid; Adfeed-d5; Ansaid-d5; Flurofen-d5; Froben-d5; Stayban-d5; Zepolas-d5; DL-2-(2-Fluoro-4-biphenylyl)propionic-d5 Acid; DL-Flurbiprofen-d5; (±)-Flurbiprofen-d5 (phenyl-d5). Grade: 95% by HPLC; 98% atom D. CAS No. 215175-76-1. Molecular formula: C15H8D5FO2. Mole weight: 249.29.
Flurbiprofen Sodium
Flurbiprofen Sodium is a nonsteroidal anti-inflammatory drug (NSAID) derived from propionic acid. It functions as a potent inhibitor of cyclooxygenase (COX) enzymes, thereby reducing the production of prostaglandins, which are mediators of pain, inflammation, and fever. Synonyms: [1,1'-Biphenyl]-4-acetic acid, 2-fluoro-α-methyl-, sodium salt (1:1); 2-(2-Fluorobiphenyl-4-yl)propionic acid sodium salt; 2-Fluoro-α-methyl-4-diphenylacetic acid sodium salt; Flurbiprofen sodium salt; Ocufen; Ocuflur; Sodium 3-fluoro-4-phenylhydratropate; Sodium flurbiprofen. Grade: ≥95%. CAS No. 56767-76-1. Molecular formula: C15H12FNaO2. Mole weight: 266.24.
Flurithromycin
A fluorinated derivative of Erythromycin. A macrolide antibiotic. Uses: Enzyme inhibitors. Synonyms: 8-Fluoroerythromycin; Fluritromicina; Antibiotic P 80206; (8S)-8-Fluoroerythromycin A; 8-Fluoroerythromycin A; P 0501A; P 80206. Grade: 95%. CAS No. 82664-20-8. Molecular formula: C37H66FNO13. Mole weight: 751.92.
Fmoc-Ala-OH-[15N]
Fmoc-Ala-OH-[15N] is a labelled Fmoc-Ala-OH. Alanine is one of the non-essential amino acids for humans. Alanine is the key compound in glucose-alanine cycle. Synonyms: N-(9-Fluorenylmethoxycarbonyl)-L-alanine-15N; Fmoc-Ala-OH (15N); Fmoc-Ala-OH-15N. Grade: 98% by HPLC; 98% atom 15N. CAS No. 117398-49-9. Molecular formula: C18H17[15N]O4. Mole weight: 312.33.
N,S-Bis-Fmoc-glutathione is a very potent inhibitor of mammalian glyoxalase II (Ki = 0.08 μM for glyoxalase II purified from calf liver). Synonyms: N,S-Bis-Fmoc-glutathione. CAS No. 149438-56-2. Molecular formula: C40H37N3O10S. Mole weight: 751.80.
Fmoc-Gly-OH-[15N]
Fmoc-Gly-OH-[15N] is the labelled analogue of Fmoc-Gly-OH. Fmoc-Gly-OH is an N-Fmoc-protected form of Glycine. Glycine is one of the non-essential amino acids for humans. Glycine is an inhibitory neurotransmitter in the central nervous system. Synonyms: N-(9-Fluorenylmethoxycarbonyl)-glycine-15N; Glycine-15N, N-Fmoc; Fmoc-Gly-OH-15N. Grade: 98% atom 15N. CAS No. 125700-33-6. Molecular formula: C17H15[15N]O4. Mole weight: 298.30.
Fmoc-Gly-OH-[2-13C]
Fmoc-Gly-OH-[2-13C] is the labelled analogue of Fmoc-Gly-OH. Fmoc-Gly-OH is an N-Fmoc-protected form of Glycine. Glycine is one of the non-essential amino acids for humans. Glycine is an inhibitory neurotransmitter in the central nervous system. Synonyms: Glycine-N-Fmoc 2-13C; Fmoc-Gly[2-13C]-OH. Grade: 98% by CP; 99% atom 13C. CAS No. 175453-19-7. Molecular formula: C16[13C]H15NO4. Mole weight: 298.30.
Fmoc-L-Cys(Biotin)-OH
Fmoc-L-Cys(Biotin)-OH.
Fmoc-Leu-OH
Fmoc-Leu-OH is an amino acid derivative. It is also one of the novel PPARγ ligands that can reduce osteoclasts differentiation through activating PPARγ. Synonyms: Fmoc-L-Leu-OH; N-(9-fluorenylmethoxycarbonyl)-L-leucine; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-leucine; NPC 15199; NPC15199; NPC-15199. Grade: 98%. CAS No. 35661-60-0. Molecular formula: C21H23NO4. Mole weight: 353.42.
Fmoc-Leu-OH-[15N]
Fmoc-Leu-OH-[15N] is a labelled L-Leucine-N-FMOC. Leucine is an α-amino acid essential for humans. Synonyms: Fmoc-Leu-OH-15N; moc-[15N]Leu-OH. Grade: 98% by CP; 98% atom 15N. CAS No. 200937-57-1. Molecular formula: C21H23[15N]O4. Mole weight: 354.41.
Fmoc-L-Lys[Oct-(otBu)-Glu-(otBu)-AEEA-AEEA]-OH
Fmoc-L-Lys[Oct-(otBu)-Glu-(otBu)-AEEA-AEEA]-OH is an intermediate in the synthesis of Semaglutide. Semaglutide is a glucagon-like peptide-1 (GLP-1) analog with significant hypoglycemic efficacy. Synonyms: Semaglutide Side Chain; (3S,30S)-3-Carboxy-30-[(1,1-dimethylethoxy)carbonyl]-9,18,27,32-tetraoxo-49-(1,1-dimethylethyl) 1-(9H-fluoren-9-ylmethyl)-11,14,20,23-tetraoxa-2,8,17,26,31-pentaazanonatetracontanedioic acid ester; (23S,50S)-50-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-23-(tert-butoxycarbonyl)-2,2-dimethyl-4,21,26,35,44-pentaoxo-3,30,33,39,42-pentaoxa-22,27,36,45-tetraazahenpentacontan-51-oic acid. CAS No. 1662688-20-1. Molecular formula: C64H101N5O16. Mole weight: 1196.5.
Fmoc-Lys(biotin-PEG12)-OH
Fmoc-Lys (biotin-PEG12)-OH is a Lysine embedded biotinylation reagent containing a carboxylic group. Reaction of carboxylic with primary amino (-NH2) forms stable, irreversible amide bonds. The Fmoc group can be removed under basic condition to obtain the free amine which can be used for further conjugations. The hydrophilic PEG spacer arm imparts water solubility that is transferred to the biotinylated molecule. Please contact us for GMP-grade inquiries. Grade: 0.98. Molecular formula: C58H91N5O19S. Mole weight: 1194.5.
Fmoc-Lys (biotin-PEG4)-OH
Fmoc-Lys (biotin-PEG4)-OH is a polyethylene glycol (PEG)-based PROTAC linker. Fmoc-Lys (biotin-PEG4)-OH can be used in the synthesis of a series of PROTACs. CAS No. 1334172-64-3. Molecular formula: C42H59N5O11S. Mole weight: 842.01.
Fmoc-N-Me-Homocys(Trt)-OH has been incorporated in cyclic somatostatin analogs. Synonyms: (S)-2-(N-Fmoc-N-methyl-amino)-4-tritylsulfanyl-butyric acid; (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)-4-(tritylthio)butanoic acid; N-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-N-methyl(triphenyl)-L-methionine; N-alpha-(9-Fluorenylmethyloxycarbonyl)-N-alpha-methyl-S-trityl-L-homocysteine; MeHcy. Grade: 95%. CAS No. 526210-71-9. Molecular formula: C39H35NO4S. Mole weight: 613.76.
Fmoc-N-Me-Phe-OH
Fmoc-N-Me-Phe-OH is an inhibitor of Malaria Parasite. Synonyms: N-(fluorenylmethoxycarbonyl)-N-methyl-L-phenylalanine; Fmoc-N-methyl-L-phenylalanine; (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)-3-phenylpropanoic acid; Fmoc-N-alpha-methyl-L-Phenylalanine; Nα-Fmoc-Nα-Methyl-L-phenylalanine. Grade: ≥99.5% by Chiral HPLC. CAS No. 77128-73-5. Molecular formula: C25H23NO4. Mole weight: 401.46.
Fmoc-Phe-OH-[15N]
Fmoc-Phe-OH-[15N] is the labelled analogue of L-Phenylalanine-N-FMOC. Phenylalanine is an α-amino acid essential for humans that is found in breast milk of mammals. It is commonly used as a dietary supplement. Synonyms: N-(9-Fluorenylmethoxycarbonyl)-L-phenylalanine-15N; L-Phenylalanine-15N N-Fmoc; Fmoc-[15N]Phe-OH; (((9H-Fluoren-9-yl)methoxy)carbonyl)-L-phenylalanine-15N. Grade: 99% (CP); 98% atom 15N. CAS No. 125700-32-5. Molecular formula: C24H21[15N]O4. Mole weight: 388.42.
Fmoc-(R)-3-amino-4-(2,4,5-trifluorophenyl)butyric Acid is an impurity of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Synonyms: N-β-(9-Fluorenylmethoxycarbonyl)-2,4,5-trifluoro-D-β-homophenylalanine; (R)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-(2,4,5-trifluorophenyl)butanoic acid. Grade: >95%. CAS No. 1217818-53-5. Molecular formula: C25H20F3NO4. Mole weight: 455.43.
Fmoc-S-acetamidomethyl-D-penicillamine
Fmoc-S-acetamidomethyl-D-penicillamine is a derivative of D-Penicillamine, which is a penicillin metabolite used in the treatment of Wilson's disease, Cystinuria, Scleroderma and arsenic poisoning. Synonyms: Fmoc-D-Pen(Acm)-OH; Fmoc-S-acetamidomethyl-β,β-dimethyl-D-Cys-OH; N-(fluorenylmethoxycarbonyl)-S-acetamidomethyl-D-penicillamine; (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-((acetamidomethyl)thio)-3-methylbutanoic acid; 3-[(Acetamidomethyl)sulfanyl]-N-{[(9H-fluoren-9-yl)methoxy]carbonyl}-D-valine. Grade: ≥95%. CAS No. 201531-77-3. Molecular formula: C23H26N2O5S. Mole weight: 442.53.
Fmoc-S-acetamidomethyl-L-penicillamine
Fmoc-S-acetamidomethyl-L-penicillamine is a derivative of D-Penicillamine, which is a penicillin metabolite used in the treatment of Wilson's disease, Cystinuria, Scleroderma and arsenic poisoning. Synonyms: Fmoc-L-Pen(Acm)-OH; Fmoc-S-acetamidomethyl-β,β-dimethyl-L-Cys-OH; Fmoc-Pen(Acm)-OH; N-(fluorenylmethoxycarbonyl)-S-acetamidomethyl-L-penicillamine; (R)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-((acetamidomethyl)thio)-3-methylbutanoic acid; Fmoc-Cys(Me2)(Acm)-OH; 3-[(Acetamidomethyl)sulfanyl]-N-{[(9H-fluoren-9-yl)methoxy]carbonyl}-L-valine. Grade: ≥95%. CAS No. 201531-76-2. Molecular formula: C23H26N2O5S. Mole weight: 442.53.
Fmoc-S-benzyl-D-penicillamine
Fmoc-S-benzyl-D-penicillamine is a derivative of D-Penicillamine, which is a penicillin metabolite used in the treatment of Wilson's disease, Cystinuria, Scleroderma and arsenic poisoning. Synonyms: Fmoc-D-Pen(Bzl)-OH; Fmoc-S-benzyl-β,β-dimethyl-D-Cys-OH; Fmoc-D-Pen(Bn)-OH; (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(benzylthio)-3-methylbutanoic acid; 3-(Benzylsulfanyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-valine; N-α-(9-Fluorenylmethoxycarbonyl)-S-benzyl-D-penicillamine. Grade: ≥95%. CAS No. 139551-73-8. Molecular formula: C27H27NO4S. Mole weight: 461.57.
Fmoc-S-trityl-D-penicillamine
Fmoc-S-trityl-D-penicillamine is a derivative of D-Penicillamine, which is a penicillin metabolite used in the treatment of Wilson's disease, Cystinuria, Scleroderma and arsenic poisoning. Synonyms: Fmoc-D-Pen(Trt)-OH; Fmoc-S-trityl-β,β-dimethyl-D-Cys-OH; (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-methyl-3-(tritylthio)butanoic acid; N-alpha-(9-Fluorenylmethyloxycarbonyl)-S-trityl-D-penicillamine; N-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-3-[(triphenylmethyl)sulfanyl]-D-valine. Grade: ≥95%. CAS No. 201532-01-6. Molecular formula: C39H35NO4S. Mole weight: 613.76.
Fmoc-S-trityl-L-penicillamine
Fmoc-S-trityl-L-penicillamine is a derivative of D-Penicillamine, which is a penicillin metabolite used in the treatment of Wilson's disease, Cystinuria, Scleroderma and arsenic poisoning. Synonyms: Fmoc-L-Pen(Trt)-OH; Fmoc-S-trityl-β,β-dimethyl-L-Cys-OH; Fmoc-Pen(Trt)-OH; (R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-methyl-3-(tritylthio)butanoic acid; N-Fmoc-3-(trityl-thio)-L-valine; N-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-3-[(triphenylmethyl)sulfanyl]-L-valine; N-alpha-(9-Fluorenylmethyloxycarbonyl)-S-trityl-L-penicillamine. Grade: ≥95%. CAS No. 201531-88-6. Molecular formula: C39H35NO4S. Mole weight: 613.77.
Fmoc-Thr[GalNAc(Ac)3-α-D]-OH
Fmoc-Thr[GalNAc(Ac)3-α-D]-OH is a biomedical compound used for the research of diseases involving abnormal glycosylation processes. It functions as a glycosylation inhibitor, targeting enzymes responsible for glycan modification. This product aids in the study and understanding of glycosylation-related disorders. Synonyms: Fmoc-Thr(Ac3AcNH-α-Gal)-OH; Fmoc-L-Thr(TnAc4)-OH; N-alpha-(9-Fluorenylmethyloxycarbonyl)-O-(2-acetamido-2-deoxy-3,4,6-tri-O-acetyl-alpha-D-galactopyranosyl)-L-threonine; Fmoc-Thr[GalNAc(Ac)3-alpha-D]-OH. Grade: ≥97% by HPLC. CAS No. 116783-35-8. Molecular formula: C33H38N2O13. Mole weight: 670.66.
Fmoc-Thr(GalNAc(Ac)3-b-D)-OH
Fmoc-Thr(GalNAc(Ac)3-b-D)-OH, a peptide product widely embraced in the biomedicine sector, has demonstrated potent inhibition against cancer cell growth, through targeting intricate cancer-specific pathways while simultaneously strengthening one's immunologic response. Furthermore, this product is endowed with anti-inflammatory properties which provide crucial therapeutic value in the treatment of various inflammatory disorders. The high purity and stability of this medicinal item make it an indispensable resource within research facilities worldwide. Synonyms: N-Fmoc-O-(2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-galactopyranosyl)-L-threonine; O-(2-Deoxy-2-acetylamino-3-O,4-O,6-O-triacetyl-beta-D-galactopyranosyl)-Fmoc-Thr-OH; L-Threonine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-O-[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]-; Fmoc-L-Thr(β-D-GalNAc(Ac)3)-OH. Grade: ≥95%. CAS No. 133575-43-6. Molecular formula: C33H38N2O13. Mole weight: 670.66.
Fmoc-Val-OH-[15N]
Fmoc-Val-OH-[15N]. Synonyms: N-(9-Fluorenylmethoxycarbonyl)-L-valine-15N; Fmoc-Val-OH-15N. Grade: 99% by CP; 98% atom 15N. CAS No. 125700-35-8. Molecular formula: C20H21[15N]O4. Mole weight: 340.38.
FMRF
FMRF is a peptide consisting of 4 amino acid residues. Uses: Membrane transport modulators. Synonyms: L-Phenylalanine, L-phenylalanyl-L-methionyl-L-arginyl-; Phenylalanyl-Methionyl-Arginyl-Phenylalanin; H-Phe-Met-Arg-Phe-OH; H-FMRF-OH. Grade: ≥95%. CAS No. 74012-06-9. Molecular formula: C29H41N7O5S. Mole weight: 599.74.
Folipastatin
Folipastatin is a fungal metabolite that is produced by A. unguis. Folipastatin is also an inhibitor of phospholipase A2 (PLA2) with an IC50 of 39 μM. Synonyms: 3,8-dihydroxy-4,9-dimethyl-1,6-bis[(1Z)-1-methyl-1-propen-1-yl]-11H-dibenzo[b,e][1,4]dioxepin-11-one; E323392EAO. Grade: ≥95%. CAS No. 139959-71-0. Molecular formula: C23H24O5. Mole weight: 380.43.
Formaldehyde, polymer with 1,3-benzenedimethanamine and 4,4-(1-methylethylidene)bisphenol
Formaldehyde, polymer with 1,3-benzenedimethanamine and 4,4-(1-methylethylidene)bisphenol. Synonyms: Formaldehyde, polymer with 1,3-benzenedimethanamine and 4,4-(1-methylethylidene)bisphenol. CAS No. 161278-17-7.
Formaldehyde, polymer with (chloromethyl)oxirane, 4,4-(1-methylethylidene)bisphenol and phenol
Formaldehyde, polymer with (chloromethyl)oxirane, 4,4-(1-methylethylidene)bisphenol and phenol. CAS No. 40216-08-8.
Formaldehyde, polymerwith (chloromethyl)oxirane and 2-methylphenol, reaction products with bisphenolA-epichlorohydrin polymer and 1,2-cyclohexanediamine
Formaldehyde, polymerwith (chloromethyl)oxirane and 2-methylphenol, reaction products with bisphenolA-epichlorohydrin polymer and 1,2-cyclohexanediamine. Grade: 95%. CAS No. 168109-77-1.
For-Met-Ala-Ser-OH
For-Met-Ala-Ser-OH is a peptide that binds to a formyl-peptide receptor on neutrophils. Synonyms: Formyl-MAS; N-Formyl-Met-Ala-Ser; formyl methionyl alanyl serine; N-formyl-L-methionyl-L-alanyl-L-serine; (S)-2-((S)-2-((S)-2-formamido-4-(methylthio)butanamido)propanamido)-3-hydroxypropanoic acid. Grade: ≥97% by HPLC. CAS No. 17351-32-5. Molecular formula: C12H21N3O6S. Mole weight: 335.38.
Formycin A
Formycin A is produced by the strain of Nocardia intriforma M4-C5. It has the activity of resistance to Salicornia, Pyricularia oryzae and Mole disease Phanerochaetehrysosporium of potato. Uses: Antineoplastic agents. Synonyms: (1S)-1-(7-amino-1H-pyrazolo[4,3-d]pyrimidin-3-yl)-1,4-anhydro-D-ribitol; NSC 102811; BRN 0624229; 7-Amino-3-beta-D-ribofuranosyl-1H-pyrazolo(4,3-d)pyrimidine. Grade: ≥ 97%. CAS No. 6742-12-7. Molecular formula: C10H13N5O4. Mole weight: 267.24.
Fortimicin A
Produced by the strain of Micromonospora olivoasterospora, it has broad antibacterial spectrum and strong antibacterial activity, and is also effective to aminoglycoside antibiotic resistant bacteria producing 3'-phosphotransferase, 2''-nucleoside transferase, 6' and 2'-acetyltransferase. Synonyms: Astromicin; Astromicina; Astromicine; Astromicinum; Antibiotic KW-1070; 4-Amino-1-((aminoacetyl)methylamino)-1,4-dideoxy-3-O-(2,6-diamino-2,3,4,6,7-pentadeoxy-beta-L-lyxo-heptopyranosyl)-6-O-methyl-L-chiro-inositol. Grade: 95%. CAS No. 55779-06-1. Molecular formula: C17H35N5O6. Mole weight: 405.49.
Foscarnet
Foscarnet is a pyrophosphate analog DNA polymerase inhibitor that has activity against several viruses, but is primarily used to treat CMV retinitis. Because it can cross the blood-brain barrier, it can be used to treat viral infections of the central nervous system. Synonyms: Phosphonoformate; Carboxyphosphonic acid; Foscarmet; Phosphonocarboxylic acid; Dihydroxyphosphinecarboxylic acid oxide; Phosphonomethanoic acid; Dihydroxyphosphanecarboxylic acid oxide; Phgosphonocarboxylic acid; NSC313410; Phosphinecarboxylic acid, 1,1-dihydroxy-, 1-oxide; Foscamet. Grade: 95%. CAS No. 4428-95-9. Molecular formula: CH3O5P. Mole weight: 126.01.
Foscarnet sodium
Foscarnet Sodium inhibits viral RNA polymerases, reverse transcriptases and DNA polymerases by non-competitive inhibition of dNTPs. It is an antiviral agent used in the treatment of cytomegalovirus retinitis. It has activity against human herpesviruses and HIV. Uses: Antiviral agents. Synonyms: Trisodium phosphonoformate; Trisodium carboxyphosphate; Foscarnet trisodium; Phosphonoformic acid trisodium salt; 1,1-Dihydroxyphosphinecarboxylic Acid 1-Oxide Sodium Salt; A 29622; EHB 776; Gefin; Triapten. Grade: >98%. CAS No. 63585-09-1. Molecular formula: CNa3O5P. Mole weight: 191.95.
Foscarnet Sodium Hexahydrate
Foscarnet Sodium Hexahydrate is an antiviral drug used in the treatment of cytomegalovirus retinitis. It has inhibitory effect on viral DNA polymerase and reverse transcriptase. Synonyms: Sodium phosphonoformate tribasic hexahydrate; 1,1-Dihydroxyphosphinecarboxylic Acid 1-Oxide Sodium Salt Hydrate; A 29622 Hydrate; EHB 776 Hydrate; Foscavir Hydrate; Gefin Hydrate; PFA Hydrate; Phosphonoformic Acid Trisodium Salt Hydrate; Triapten Hexahydrate; Trisodium Phosphonoformate Hexahydrate. Grade: 95%. CAS No. 34156-56-4. Molecular formula: CH12Na3O11P. Mole weight: 300.04.
Fosfomycin
Fosfomycin is produced by the strain of Streptomyces fradiae and Str. viridochromogenes. It competitively inhibits enol pyruvate transferase and blocks the early stages of bacterial cell wall synthesis. And it has anti-gram positive bacteria and negative bacteria activity. Uses: Anti-bacterial agents. Synonyms: Veramina; phosphomycin; Fosfomycinum; L-cis-1,2-epoxypropylphosphonic acid; (-)-(1R,2S)-(1,2-Epoxypropyl)phosphonic acid; (1R,2S)-epoxypropylphosphonate; cis-(1R,2S)-epoxypropylphosphonic acid; 1R-cis-(1,2-epoxypropyl)phosphonic acid. Grade: 98%. CAS No. 23155-02-4. Molecular formula: C3H7O4P. Mole weight: 138.06.
Fosfomycin sodium
Fosfomycin Disodium Salt is an antibiotic produced by Streptomyces fradiae. It is used to treat uncomplicated urinary tract infections and is used for susceptibility studies of Klebsiella pneumoniae. Synonyms: Phosphomycin disodium salt; (-)-(1R,2S)-(1,2-Epoxypropyl)phosphonic acid disodium salt; (1,2-Epoxypropyl)-, disodium salt (1r,2s)(-)-phosphonic acid; (2r-cis)-(3-Methyloxiranyl)phosphonic acid disodium salt; (3-Methyloxiranyl)-, disodium salt, (2r-cis). Grade: >95%. CAS No. 26016-99-9. Molecular formula: C3H5Na2O4P. Mole weight: 182.02.
Fosmidomycin
Fosmidomycin is produced by the strain of Streptomyces lavendulae 8006. Fosmidomycin has anti-gram-positive and anti-gram-negative activities. Synonyms: Fosmidomycina; 3-(N-hydroxyformamido)propylphosphonic acid; FR-31564. Grade: 95%. CAS No. 66508-53-0. Molecular formula: C4H10NO5P. Mole weight: 183.10.
Fosmidomycin sodium salt
Fosmidomycin is an antimalarial and antibiotic originally isolated from culture broths of bacteria of the genus Streptomyces and has been used as an inhibitor of DOXP reductoisomerase, a key enzyme in the non-mevalonate pathway of isoprenoid biosynthesis. Synonyms: Antibiotic FR31564; FR31564; P-[3-(formylhydroxyamino)propyl]-phosphonic acid, monosodium salt; (3-(N-Hydroxyformamido)propyl)phosphonic acid sodium salt; Phosphonic acid, (3-(formylhydroxyamino)propyl)-, monosodium salt. Grade: ≥95%. CAS No. 66508-37-0. Molecular formula: C4H9NO5P.Na. Mole weight: 205.08.
Fostriecin
The most fully characterised member of a family of phosphate esters of a triene antibiotic; a topoisomerase II inhibitor; selective inhibition of protein phosphatase PP2A. Synonyms: (1E,7E,9E,11E)-3,6,13-trihydroxy-3-methyl-1-(6-oxo-3,6-dihydro-2H-pyran-2-yl)trideca-1,7,9,11-tetraen-4-yl dihydrogen phosphate; 2H-Pyran-2-one, 5,6-dihydro-6-[3,6,13-trihydroxy-3-methyl- 4-(phosphonooxy)-1,7,9,11-tridecatetraenyl]-, monosodiumsalt. Grade: >95% by HPLC. CAS No. 87810-56-8. Molecular formula: C19H27O9P. Mole weight: 430.39.
Foxy-5
A Wnt5a peptide mimetic. It has been undergoing clinical trials for the treatment of prostate cancer, colorectal cancer, metastatic colon cancer, metastatic breast cancer, and metastatic prostate cancer. Synonyms: Foxy 5; Foxy5; (2S)-2-[[(2S)-4-carboxy-2-[[(2R)-2-[[2-[[(2S)-3-carboxy-2-[[(2S)-2-formamido-4-methylsulfanylbutanoyl]amino]propanoyl]amino]acetyl]amino]-3-sulfanylpropanoyl]amino]butanoyl]amino]-4-methylpentanoic acid. Grade: >95%. CAS No. 881188-51-8. Molecular formula: C26H42N6O12S2. Mole weight: 694.8.
FR 179642 is an impurity of Micafungin, which is an antifungal agent. Synonyms: FR-179642; FR179642; Pneumocandin M1; 1-[(4R,5R)-4,5-Dihydroxy-L-ornithine]-4-[(4S)-4-hydroxy-4-[4-hydroxy-3-(sulfooxy)phenyl]-L-threonine]pneumocandin A0; 1-[(4R,5R)-4,5-Dihydroxy-L-ornithine]-4-[(S)-4-hydroxy-4-[4-hydroxy-3-(sulfooxy)phenyl]-L-threonine]pneumocandin A0; CMICA; FR 133303. Grade: ≥95%. CAS No. 168110-44-9. Molecular formula: C35H52N8O20S. Mole weight: 936.89.
FR198248
FR-198248, a new type of hydroxyl benzaldehyde compound, was isolated from the cultured broth of a fungal strain identified as Aspergillus terreus from morphological characteristics. FR-198248 exhibited anti-influenza virus activity in Madin-Darby canine kidney (MDCK) cells in vitro. Synonyms: FR-198248; 1,5,6,7-Isobenzofurantetrol, 1,3-dihydro-4-methyl-; 197316-54-4; 1-O-Demethyl-FR-202306; 6ZL0C9ER7N; 2,3,4-trihydroxy-6-(hydroxymethyl)-5-methylbenzaldehyde; 364342-83-6; UNII-6ZL0C9ER7N; SCHEMBL1527081; Q27265782. Grade: >98%. CAS No. 197316-54-4. Molecular formula: C9H10O5. Mole weight: 198.17.
FR-900098
FR-900098 is produced by the strain of Streptomyces rubellomurinus subsp. indigoferus 24. FR-900098 has anti-gram-positive and anti-gram-negative activities. Synonyms: Antibiotic FR-900098; FR 900098; BRN 2096083; 3-(N-acetyl-N-hydroxy)aminopropylphosphonic acid. Grade: >98%. CAS No. 66508-32-5. Molecular formula: C5H12NO5P. Mole weight: 197.13.
FR-900490
FR-900490 is a new type of immunoactive substance isolated from Disocia sp. F-11809. It is effective in reversing the damage to bone marrow caused by mitomycin C. Uses: Fr-900490 is effective in reversing the damage to bone marrow caused by mitomycin c. Synonyms: FR 900490; FR900490; BMY 28700; BMY28700; BMY-28700; (2S,3R)-2-[(L-Asparaginyl)amino]-3-[[(S)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]amino]butanoic acid. Grade: >98%. CAS No. 105424-59-7. Molecular formula: C14H22N6O6. Mole weight: 370.36.
FR 901235
This active molecular is an immunoactive substance produced by Paecilomyces carneus F-4882, an imperfect fungus. FR-901235 can lead the mitogen-induced lymphocyte proliferation to go back to a normal level after being suppressed by addition of immunosuppressive factor. Synonyms: FR-901235; (-)-2,4,9-Trihydroxy-6-methoxy-7-methyl-2-(2-oxopropyl)-1H-phenalene-1,3(2H)-dione. Grade: 95%. CAS No. 124190-19-8. Molecular formula: C18H16O7. Mole weight: 344.31.
FR 901379
FR 901379 is an impurity of Micafungin, a lipopeptide compound that acts as an antifungal agent with activity against Aspergillus and Candida species. FR901379 is an echinocandin-like antifungal lipopeptide with inhibitory activity against C. albicans, C. krusei, C. tropicalis, C. utilis, A. fumigatus, and A. niger fungi (IC50s = <0.003-1.9 μg/ml). FR 901379 has a protective effect against C. albicans infection in mice (ED50 = 1.1 mg/kg). It also reduces the number of lung cysts and trophozoites in a mouse model of Plasmodium carinii infection. Synonyms: 1-[(4R,5R)-4,5-Dihydroxy-N2-(1-oxohexadecyl)-L-ornithine]-4-[(4S)-4-hydroxy-4-[4-hydroxy-3-(sulfooxy)phenyl]-L-threonine]pneumocandin A0; (2α,3β,4β)-(4R,5R)-4,5-Dihydroxy-N2-(1-oxohexadecyl)-L-ornithyl-L-threonyl-trans-4-hydroxy-L-prolyl-(S)-4-hydroxy-4-[4-hydroxy-3-(sulfooxy)phenyl]-L-threonyl-3-hydroxy-L-glutaminyl-3-hydroxy-4-methyl-L-Proline Cyclic (6→1)-Peptide; 1H-Dipyrrolo[2,1-c:2',1'-l][1,4,7,10,13,16]hexaazacycloheneicosine Cyclic Peptide Deriv. Grade: ≥90%. CAS No. 144371-88-0. Molecular formula: C51H82N8O21S. Mole weight: 1175.30.
FR-901464
It is a potent cell cycle inhibitor isolated from Pseudomonas sp. No.2663. It exhibits potent antitumor activities against tumor cell lines via binding to the spliceosome and modulating pre-mRNA splicing. Synonyms: Fr901464; 2-Pentenamide, 4-(acetyloxy)-N-[(2R,3R,5S,6S)-6-[(2E,4E)-5-[(3R,4R,5R,7S)-4,7-dihydroxy-7-methyl-1,6-dioxaspiro[2.5]oct-5-yl]-3-methyl-2,4-pentadien-1-yl]tetrahydro-2,5-dimethyl-2H-pyran-3-yl]-, (2Z,4S)-; WB 2663B; Antibiotic WB 2663B; Antibiotic FR 901464. Grade: 90%. CAS No. 146478-72-0. Molecular formula: C27H41NO8. Mole weight: 507.62.
FR 901537
FR-901537, a naphthothiazin compound, has been found to be an aromatase inhibitor that could be used as a cytostatic antibiotic and was once studied in breast cancer. Synonyms: FR-901537; FR901537; (R)-N-(3-((2-((2,3-Dihydro-6-hydroxy-2-oxo-1H-naphtho(2,1-b)(1,4)thiazin-5-yl)thio)ethyl)amino)-3-oxopropyl)-2,4-dihydroxy-3,3-dimethylbutanamide. Grade: 98%. CAS No. 161162-21-6. Molecular formula: C23H29N3O6S2. Mole weight: 507.62.
Frequentin
Produced by the strain of Penicillum frequentans and Pen. palitans, Frequentin has the activity of resisting ear mold, mucor mold, ploughshare mold and aspergillus. Synonyms: Frequentine; 6-[(1E,3E)-hepta-1,3-dienyl]-3,4-dihydroxy-2-oxocyclohexane-1-carbaldehyde; 6-hepta-1,3-dienyl-3,4-dihydroxy-2-oxocyclohexane-1-carbaldehyde. Grade: >98%. CAS No. 29119-03-7. Molecular formula: C14H20O4. Mole weight: 252.31.
FSL-1
FSL 1 is a TLR2/6 peptide agonist (also a putative TLR10 ligand) that activates NF-κB. FSL 1 induces the expression of some pro-inflammatory cytokines such as IL-8, IL-1β, CCL20 and TNF-α in vitro. Synonyms: FSL 1; FSL1; L-Phenylalanine, S-[2,3-bis[(1-oxohexadecyl)oxy]propyl]-L-cysteinylglycyl-L-α-aspartyl-L-prolyl-L-lysyl-L-histidyl-L-prolyl-L-lysyl-L-seryl-; S-[2,3-Bis[(1-oxohexadecyl)oxy]propyl]-L-cysteinylglycyl-L-α-aspartyl-L-prolyl-L-lysyl-L-histidyl-L-prolyl-L-lysyl-L-seryl-L-phenylalanine; FSL-1 lipoprotein, synthetic; Fibroblast-stimulating lipopeptide-1; Pam2-Cys-Gly-Asp-Pro-Lys-His-Pro-Lys-Ser-Phe-OH. Grade: ≥95%. CAS No. 322455-70-9. Molecular formula: C84H140N14O18S. Mole weight: 1666.16.
FSLLRY-NH2
FSLLRY-NH2 is a selective PAR2 peptide antagonist. It reverses taxol-induced mechanical allodynia, heat hyperalgesia and PKC activation in ICR mice, also suppresses ERK activation and collagen production in isolated cardiac fibroblasts. Synonyms: [Phe1,Ser2,Tyr6]-PAR-1 (1-6) amide (human). CAS No. 245329-02-6. Molecular formula: C39H60N10O8. Mole weight: 796.97.
FSLLRY-NH2 TFA
FSLLRY-NH2 TFA is a selective PAR2 peptide antagonist. It reverses taxol-induced mechanical allodynia, heat hyperalgesia and PKC activation in ICR mice, and also suppresses ERK activation and collagen production in isolated cardiac fibroblasts. Synonyms: H-Phe-Ser-Leu-Leu-Arg-Tyr-NH2.TFA; L-phenylalanyl-L-seryl-L-leucyl-L-leucyl-L-arginyl-L-tyrosinamide trifluoroacetic acid. Grade: ≥95%. Molecular formula: C41H61F3N10O10. Mole weight: 910.99.
FTase Inhibitor I
FTase inhibitor I is a potent and selective farnesyltransferase (FTase) inhibitor with an IC50 of 21 nM, which is 30-fold higher for FTase over geranylgeranyl transferase (GGTase; IC50 = 790 nM). Synonyms: Farnesyltransferase Inhibitor I; B581; N-[(2S)-2-[[(2R)-2-amino-3-mercaptopropyl]amino]-3-methylbutyl]-L-phenylalanyl-L-methionine. Grade: ≥95%. CAS No. 149759-96-6. Molecular formula: C22H38N4O3S2. Mole weight: 470.69.
FTase Inhibitor II
FTase Inhibitor II is a cell-permeable analog of farnesyl pyrophosphate (FPP) that potently inhibits FTase with an IC50 of 50-75 nM, and it does not inhibit geranylgeranyl transferase at similar concentrations (IC50 > 100 μM). FTase Inhibitor II is a possible cancer therapeutic agent. Synonyms: Farnesyltransferase Inhibitor II; FTI-II; N-[4-[[(2R)-2-amino-3-mercapto-1-oxopropyl]amino]benzoyl]-L-methionine. Grade: ≥80%. CAS No. 156707-43-6. Molecular formula: C15H21N3O4S2. Mole weight: 371.47.
FTY720 phenoxy-biotin
FTY720 is a potent agonist at four of the five sphingosine-1-phosphate (S1P) receptors. Biotin-FTY720 is a biotin-tagged analog of FTY720. The hydroxy methyl side chain of FTY720 that is targeted for phosphorylation by sphingosine kinases is retained in this analog, which means that it would likewise be phosphorylated in vivo. Synonyms: 2-amino-2-[2-(4-octylphenyl)ethyl]-1,3-propanediol-N-biotinoyl-1,5-diampentane. Grade: ≥95%. Molecular formula: C27H44N4O5S·HCl. Mole weight: 573.2.
Fumagillin
Fumagillin is a compound isolated from the fungus Aspergillus fumigatus. Fumagillin is an antimicrobial agent used in the treatment of microsporidiosis. Fumagillin shows promise as both an anti-infective and antiangiogenic agent. Synonyms: NSC-9168; Fumidil B; Fumagillin; Fumagilina; Fugillin; Fumidil. Grade: >98%. CAS No. 23110-15-8. Molecular formula: C26H34O7. Mole weight: 458.54.
Fumaramidmycin
An antibiotic originally isolated from Streptomyces kurssanovii NR-7GG1. It has the activity against gram-positive bacteria and negative bacteria (individual). Synonyms: Antibiotic C 9154; trans-N-(Phenylacetyl)-2-butenediamide; Ro 09-0049; N1-(2-phenylacetyl)fumaramide. Grade: ≥98%. CAS No. 57687-92-0. Molecular formula: C12H12N2O3. Mole weight: 232.23.
Fumonisin B1
Fumonisin B1 is produced by the strain of Gibberella fujikuroi and Fumarium moniliforme. It is a liver toxin, which can activate the cancer promoter and cause liver cancer. It has been reported that it is related to the occurrence of human esophageal cancer in South Africa and other places. It can also cause pig pulmonary edema, and is also the pathogenic substance of equine leukoencephalitis. Fumonisin B1 inhibits sphingosine acyltransferase. Synonyms: Macrofusine; Macrofusine; NSC 629151; (R)-3-Carboxy-pentanedioic acid mono-{(1S,3S,5R,10R,12S,13S)-13-amino-1-[(1R,2R)-1-((R)-3,4-dicarboxy-butyryloxy)-2-methyl-hexyl]-5,10,12-trihydroxy-3-methyl-tetradecyl} ester. Grade: ≥98%. CAS No. 116355-83-0. Molecular formula: C34H59NO15. Mole weight: 721.83.
Fumonisin B1-[13C34]
Fumonisin B1-[13C34] is the labelled analogue of Fumonisin B1. Fumonisin B1 is a mycotoxin derived from Fusarium and their Liseola section. Synonyms: Fumonisin B1-13C34. CAS No. 1217458-62-2. Molecular formula: [13C]34H59NO15. Mole weight: 755.58.
Fumonisin B1-[13C4]
Fumonisin B1-[13C4] is the labelled analogue of Fumonisin B1. Fumonisin B1 is a mycotoxin derived from Fusarium and their Liseola section. Synonyms: (2R,2'R)-1,2,3-Propanetricarboxylic Acid 1,1'-[(1S,2R)-1-[(2S,4R,9R,11S,12S)-12-Amino-4,9,11-trihydroxy-2-methyltridecyl]-2-[(1R)-1-methylpentyl]-1,2-ethanediyl] Ester-13C4; Fumonisin B1-13C4. CAS No. 1324564-22-8. Molecular formula: C30[13C]4H59NO15. Mole weight: 725.8.
Fumonisin B2
Fumonisin B2 is a liver toxin produced by Gibberella fujikuroi and Fumarium moniliforme. It is more cytotoxic than fumonisin B1. Fumonisin B2 inhibits sphingosine acyltransferase. Uses: Carcinogens, environmental. Synonyms: 1,2,3-Propanetricarboxylic acid, 1,1'-(1-(12-amino-9,11-dihydroxy-2-methyltridecyl)-2-(1-methylpentyl)-1,2-ethanediyl) ester. Grade: >95%. CAS No. 116355-84-1. Molecular formula: C34H59NO14. Mole weight: 705.85.
Fumonisin B2-[13C34]
Fumonisin B2-[13C34] is the labelled analogue of Fumonisin B1. Fumonisin B2 is a mycotoxin derived from Fusarium and their Liseola section. Synonyms: Fumonisin B2-13C34. CAS No. 1217481-36-1. Molecular formula: [13C]34H59NO14. Mole weight: 739.58.