BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| HIV-1 TAT Protein Peptide | It is a cell-permeable peptide (CPP) derived from the HIV-1 tat protein transduction domain (PTD), which has been shown to promote the entry of nucleic acids into several cell types. Synonyms: HIV-1 Tat Protein (47-57); H-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-OH; TAT (47-57); L-tyrosyl-glycyl-L-arginyl-L-lysyl-L-lysyl-L-arginyl-L-arginyl-L-glutaminyl-L-arginyl-L-arginyl-L-arginine. Grade: 98%. CAS No. 191936-91-1. Molecular formula: C64H118N32O14. Mole weight: 1559.83. |  |
| HIV-IN petide | Arg-Val-Leu-(R)-Phe-Glu-Ala-Nle-NH2 contains a reduced peptide bond and is a competitive inhibitor of the HIV-1 protease with a Ki of 50 nM. Synonyms: 167875-35-6; HIV-IN petide; H-Arg-Val-Leu-psi(CH2NH)Phe-Glu-Ala-Nle-NH2; (4S)-4-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylbutanoyl]amino]-4-methylpentyl]amino]-3-phenylpropanoyl]amino]-5-[[(2S)-1-[[(2S)-1-amino-1-oxohexan-2-yl]amino]-1-oxopropan-2-yl]amino]-5-oxopentanoic acid; Arg-Val-Leu-(R)-Phe-Glu-Ala-Nle-NH2; 107475-09-2; N-[(2r)-2-({n~5~-[amino(Iminio)methyl]-L-Ornithyl-L-Valyl}amino)-4-Methylpentyl]-L-Phenylalanyl-L-Alpha-Glutamyl-L-Alanyl-L-Norleucinamide; 2aoe; 0Q4; Peptide Inhibitor CA/p2; N-1270; R-V-L-r-F-E-A-Nle; BDBM13935; HY-P4543; MFCD00237446; H-Arg-Val-Leu-r-Phe-Glu-Ala-Nle-NH2; DA-53842; CS-0655006; (4S)-4-[(2S)-2-{[(2S)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-methylbutanamido]-4-methylpentyl]amino}-3-phenylpropanamido]-4-{[(1S)-1-{[(1S)-1-carbamoylpentyl]carbamoyl}ethyl]carbamoyl}butanoic acid. Grade: ≥95%. CAS No. 167875-35-6. Molecular formula: C40H69N11O8. Mole weight: 832.04. | |
| HIV p17 Gag 77-85 | HIV p17 Gag 77-85 is used in the research of anti-HIV. Synonyms: HIV-1 gag Protein p17 (76-84); H-Ser-Leu-Tyr-Asn-Thr-Val-Ala-Thr-Leu-OH; L-seryl-L-leucyl-L-tyrosyl-L-asparagyl-L-threonyl-L-valyl-L-alanyl-L-threonyl-L-leucine; HIV P17 GAG (77-85). Grade: ≥95%. CAS No. 147468-65-3. Molecular formula: C44H72N10O15. Mole weight: 981.10. | |
| H-Leu-Pro-Pro-OH | H-Leu-Pro-Pro-OH, the proline-rich tripeptide, has ACE-inhibiting activity as IPP and VPP, with an IC50 of 9.6 μM. Synonyms: H-LPP-OH; L-leucyl-L-prolyl-L-proline; 1-(1-L-Leucyl-L-prolyl)-L-proline; leucyl-prolyl-proline. Grade: 95%. CAS No. 121305-26-8. Molecular formula: C16H27N3O4. Mole weight: 325.41. | |
| H-Lys-Phe-OH. HCl | H-Lys-Phe-OH exerts a remarkable ACE- and renin-inhibitory activity. Synonyms: L-Lysyl-L-phenylalanine hydrochloride. CAS No. 4078-58-4. Molecular formula: C15H24ClN3O3. Mole weight: 329.82. | |
| H-MET-ARG-PHE-ALA-OH | H-Met-Arg-Phe-Ala-OH is a substrate for dipeptidyl peptidase III from human erythrocytes and for snapalysin. It has been shown to be a competitive inhibitor of an enkephalin-generating endopeptidase isolated from rat brain. Synonyms: L-Methionyl-L-arginyl-L-phenylalanyl-L-alanine. CAS No. 67368-29-0. Molecular formula: C23H37N7O5S. Mole weight: 523.65. | |
| H-MET-TRP-OH | H-MET-TRP-OH is an incomplete breakdown product of protein digestion or protein catabolism. It is a non-competitive inhibitor of angiotensin-1 converting enzyme (ACE), with an IC50 of 9.8 μM. Synonyms: Methionyltryptophan; L-Methionyl-L-tryptophan; Met-trp; L-Met-L-Trp; N-L-methionyl-L-tryptophan. Grade: 95%. CAS No. 60535-02-6. Molecular formula: C16H21N3O3S. Mole weight: 335.42. | |
| HODHBt | HOOBt is a STAT5-SUMO protein-protein interaction inhibitor that suppresses SUMOylation of phosphorylated STAT5. Synonyms: 28230-32-2; 3-Hydroxy-1,2,3-benzotriazin-4(3H)-one; HOOBT; HODHBT; 3,4-Dihydro-3-hydroxy-4-oxo-1,2,3-benzotriazine; 3-hydroxy-1,2,3-benzotriazin-4-one; 3-Hydroxy-1,2,3-ben zotriazin-4(3H)-one; 1,2,3-Benzotriazin-4(3H)-one, 3-hydroxy-; Z5000NB5EL; 3-HYDROXYBENZO[D][1,2,3]TRIAZIN-4(3H)-ONE; NSC-279266; 3-HYDROXY-3,4-DIHYDRO-1,2,3-BENZOTRIAZIN-4-ONE; 3-hydroxy-4-oxo-3,4-dihydro-1,2,3-benzotriazine; E. Grade: 98% (HPLC). CAS No. 28230-32-2. Molecular formula: C23H27N3O5. Mole weight: 425.5. | |
| H-p-Chloro-Phe-D-Cys-β-(3-pyridyl)-Ala-D-Trp-Lys-tBu-Gly-Cys-2-Nal-NH2 | H-p-Chloro-Phe-D-Cys-β-(3-pyridyl)-Ala-D-Trp-Lys-tBu-Gly-Cys-2-Nal-NH2 is a highly potent human somatostatin subtype 2 receptor (hsst2) antagonist with Kis of >1000, 12, 100±57, 895 and 520 nM for hsst1, hsst2, hsst3, hsst4 and hsst5, respectively. Synonyms: PRL-2915; 4-chloro-L-phenylalanyl-D-cysteinyl-3-(3-pyridyl)-L-alanyl-D-tryptophyl-L-lysyl-2-tert-butyl-L-glycyl-L-cysteinyl-3-(2-naphthyl)-L-alaninamide (2->7)-disulfide; H-Phe(4-Cl)-D-Cys-3Pal-D-Trp-Lys-Gly(tBu)-Cys-2Nal-NH2 (Disulfide bridge: Cys2-Cys7); Cpa-D-Cys-Pal-D-Trp-Lys-Tle-Cys-Nal-amide. Grade: 95%. CAS No. 209006-18-8. Molecular formula: C59H71ClN12O8S2. Mole weight: 1175.87. | |
| H-Phg(4-OH)-OH | A carnitine palmitoyltransferase-1 inhibitor. It has been shown to improve whole-body glucose tolerance and insulin sensitivity in high-fat diet-induced obese mouse with insulin resistance. Uses: Enzyme inhibitors. Synonyms: Oxfenicine; 4-Hydroxy-L-phenylglycine; L-4-Hydroxyphenylglycine; (2S)-2-amino-2-(4-hydroxyphenyl)acetic acid. Grade: ≥98%. CAS No. 32462-30-9. Molecular formula: C8H9NO3. Mole weight: 167.16. | |
| H-Pro-NH2 | An impurity of Vildagliptin. Vildagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor that is used as an anti-hyperglycemic agent. Vildagliptin could reduce hyperglycemia in type 2 diabetes mellitus via the suppressive effect of inactivation of GLP-1 and GIP by DPP-4. Synonyms: L-Prolinamide; (2S)-2-Pyrrolidinecarboxamide; (-)-Prolinamide; (2S)-2-Carbamoylpyrrolidine; (2S)-Pyrrolidine-2-carboxylic acid amide; (S)-2-(Aminocarbonyl)pyrrolidine; (S)-Prolinamide; (S)-Proline Amide; 2-Pyrrolidinecarboxamide, (2S)-; 2-Pyrrolidinecarboxamide, (S)-; Prolinamide, L-; (S)-Pyrrolidine-2-carboxamide; (S)-Pyrrolidine-2-carboxylic acid amide; L-Proline amide. Grade: ≥95%. CAS No. 7531-52-4. Molecular formula: C5H10N2O. Mole weight: 114.10. | |
| HQNO | It is produced by the strain of Pseudomonas pyocyanea, P. aeruginosa, P. methanica. HQNO is a quinolone inhibitor that blocks NADH oxidase (NADH) and Na+-dependent NADH-quinone reductase (NQR). It has weak anti-gram-positive bacterial activity. It can inhibit the microsomal respiratory chain and 5-lipoxygenase of cytochrome BC1 complex, and antagonize the antibacterial activity of dihydrostreptomycin. Synonyms: Antibiotic KF 8940; 2-Heptyl-1-hydroxy-4-(1H)-quinolinone; 2-heptyl-4-hydroxyquinoline n-oxide; HOQNO; 2-Heptyl-4-quinolinol 1-oxide; 2-heptylquinolin-4-ol 1-oxide; 2-(n-Heptyl)-4-hydroxyquinoline N-oxide. Grade: ≥98%. CAS No. 341-88-8. Molecular formula: C16H21NO2. Mole weight: 259.34. | |
| HS 014 | HS 014 is a potent and selective melanocortin MC4 receptor antagonist (Ki = 3.16, 108, 54.4 and 694 nM for cloned human MC4, MC1, MC3 and MC5 receptors, respectively). HS 014 promotes food intake in rats and nociception in mice following central administration in vivo. HS 014 also inhibits IL-1β-induced Fos expression in the paraventricular hypothalamus. Synonyms: HS 014; HS014; HS-014. CAS No. 207678-81-7. Molecular formula: C71H94N20O17S2. Mole weight: 1563.77. | |
| HS 014 acetate | HS 014 acetate is a potent and selective melanocortin MC4 receptor antagonist with Kis of 3.16, 108, 54.4 and 694 nM for cloned human MC4, MC1, MC3 and MC5 receptors, respectively. HS 014 promotes food intake in rats and nociception in mice following central administration in vivo. HS 014 also inhibits IL-1β-induced Fos expression in the paraventricular hypothalamus. Synonyms: HS014 acetate; HS-014 acetate; Ac-Cys-Glu-His-D-2Nal-Arg-Trp-Gly-Cys-Pro-Pro-Lys-Asp-NH2.CH3CO2H (Disulfide bridge: Cys1-Cys8); N-acetyl-L-cysteinyl-L-alpha-glutamyl-L-histidyl-3-(2-naphthyl)-D-alanyl-L-arginyl-L-tryptophyl-glycyl-L-cysteinyl-L-prolyl-L-prolyl-L-lysyl-L-isoasparagine (1->8)-disulfide acetic acid. Grade: ≥95%. Molecular formula: C73H98N20O19S2. Mole weight: 1623.83. | |
| HS 024 | HS 024 is a potent melanocortin MC4 receptor antagonist (Ki = 0.29, 18.6, 5.45 and 3.29 nM for cloned human MC4, MC1, MC3 and MC5 receptors, respectively). HS 024 promotes food intake, blocks α-MSH- and MTII-induced hypotension and bradycardia in rats, following central administration in vivo. Synonyms: Acetyl-(Cys3,Nle4,Arg5,D-2-Nal7,Cys11)-α-MSH (3-11) amide; N-acetyl-L-cysteinyl-L-norleucyl-L-arginyl-L-histidyl-3-(2-naphthyl)-D-alanyl-L-arginyl-L-tryptophyl-glycyl-L-cysteinamide (1->9)-disulfide; Ac-Cys(1)-Nle-Arg-His-D-2Nal-Arg-Trp-Gly-Cys(1)-NH2; HS024; HS-024. Grade: ≥95%. CAS No. 212370-59-7. Molecular formula: C58H79N19O10S2. Mole weight: 1266.52. | |
| H-Trp-Val-OH | H-Trp-Val-OH is an effective non-competitive inhibitor of xanthine oxidase, and also inhibits DPP IV, contrary to the inverse dipeptide. Synonyms: H-WV-OH; L-tryptophyl-L-valine; tryptophanyl-valine; L-Trp-L-Val-OH; (S)-2-[(S)-2-Amino-3-(1H-indol-3-yl)-propionylamino]-3-methyl-butyric acid. Grade: ≥95% by HPLC. CAS No. 24613-12-5. Molecular formula: C16H21N3O3. Mole weight: 303.35. | |
| H-Tyr-Ile-Gly-Ser-Arg-NH2 | H-Tyr-Ile-Gly-Ser-Arg-NH2 binds to laminin receptor and inhibits experimental metastasis formation. Compared with YIGSR, C-terminal amidation significantly increases peptide activity. Synonyms: YIGSR amide; H-YIGSR-NH2; L-Argininamide, L-tyrosyl-L-isoleucylglycyl-L-seryl-; L-tyrosyl-L-isoleucyl-glycyl-L-seryl-L-argininamide; L-Tyrosyl-L-isoleucylglycyl-L-seryl-N5-(diaminomethylene)-L-ornithinamide. Grade: 95%. CAS No. 110590-65-3. Molecular formula: C26H43N9O7. Mole weight: 593.68. | |
| H-TYR-LEU-OH | H-TYR-LEU-OH is a dipeptide from β-lactoglobulin and it shows ACE-inhibitory activity with an IC50 of 122.1 μmol. Synonyms: Tyrosylleucine; L-Tyrosyl-L-leucine; Tyr-leu; Tyrosyl-Leucine; (S)-2-((S)-2-Amino-3-(4-hydroxyphenyl)propanamido)-4-methylpentanoic acid. CAS No. 17355-10-1. Molecular formula: C15H22N2O4. Mole weight: 294.35. | |
| H-TYR-TYR-OH | Tyr-Tyr and Tyr-Tyr-Tyr efficiently inhibit angiotensin I-converting enzyme (ACE) from rabbit lung, their IC50 values were 34 μM and 51 μM, respectively. These two tyrosine peptides exhibited a mix of competitive and noncompetitive inhibitions. Synonyms: Tyr-tyr; Tyrosyltyrosine; L-Tyrosyl-L-tyrosine; Peptide tyrosine-tyrosine; L-Tyr-L-Tyr; N-L-tyrosyl-L-tyrosine. Grade: 95%. CAS No. 1050-28-8. Molecular formula: C18H20N2O5. Mole weight: 344.36. | |
| Human neutrophil peptide-1 | Human neutrophil peptide-1 is an antimicrobial peptide found in Homo sapiens (Human). It belongs to the alpha-defensin family and has antimicrobial activity against gram-negative bacteria, gram-positive bacteria and Fungi. Synonyms: H-Ala-Cys(1)-Tyr-Cys(2)-Arg-Ile-Pro-Ala-Cys(3)-Ile-Ala-Gly-Glu-Arg-Arg-Tyr-Gly-Thr-Cys(2)-Ile-Tyr-Gln-Gly-Arg-Leu-Trp-Ala-Phe-Cys(3)-Cys(1)-OH; L-alanyl-L-cysteinyl-L-tyrosyl-L-cysteinyl-L-arginyl-L-isoleucyl-L-prolyl-L-alanyl-L-cysteinyl-L-isoleucyl-L-alanyl-glycyl-L-alpha-glutamyl-L-arginyl-L-arginyl-L-tyrosyl-glycyl-L-threonyl-L-cysteinyl-L-isoleucyl-L-tyrosyl-L-glutaminyl-glycyl-L-arginyl-L-leucyl-L-tryptophyl-L-alanyl-L-phenylalanyl-L-cysteinyl-L-cysteine (2->30),(4->19),(9->29)-tris(disulfide); Human Defensin NP-1; alpha-Defensin-1; Defensin HNP-1 (human); HNP-1; Defensin human neutrophil peptide-1. Grade: >95%. CAS No. 99287-08-8. Molecular formula: C150H222N44O38S6. Mole weight: 3442.03. | |
| Huwentoxin IV | Huwentoxin IV is a selective NaV1.7 channel blocker with preference for neuronal NaV1.7, 1.2 and 1.3 (IC50 = 26, 150 and 338 nM, respectively). Huwentoxin IV inhibits the channel via binding at the neurotoxin receptor site 4 in the S3-S4 linker of domain II, trapping the voltage sensor in the inward, closed configuration. Synonyms: HWTX-IV; H-Glu-Cys(1)-Leu-Glu-Ile-Phe-Lys-Ala-Cys(2)-Asn-Pro-Ser-Asn-Asp-Gln-Cys(3)-Cys(1)-Lys-Ser-Ser-Lys-Leu-Val-Cys(2)-Ser-Arg-Lys-Thr-Arg-Trp-Cys(3)-Lys-Tyr-Gln-Ile-NH2; L-alpha-glutamyl-L-cysteinyl-L-leucyl-L-alpha-glutamyl-L-isoleucyl-L-phenylalanyl-L-lysyl-L-alanyl-L-cysteinyl-L-asparagyl-L-prolyl-L-seryl-L-asparagyl-L-alpha-aspartyl-L-glutaminyl-L-cysteinyl-L-cysteinyl-L-lysyl-L-seryl-L-seryl-L-lysyl-L-leucyl-L-valyl-L-cysteinyl-L-seryl-L-arginyl-L-lysyl-L-threonyl-L-arginyl-L-tryptophyl-L-cysteinyl-L-lysyl-L-tyrosyl-L-glutaminyl-L-isoleucinamide (2->17),(9->24),(16->31)-tris(disulfide). Grade: >99%. CAS No. 526224-73-7. Molecular formula: C174H278N52O51S6. Mole weight: 4106.79. | |
| Huwentoxin XVI | Huwentoxin XVI is a potent and selective N-type Ca2+ channel blocker (IC50 ~ 60 nM) with no inhibitory effect on T-type Ca2+ channels, K+ channels or Na+ channels. Huwentoxin XVI exhibits analgesic effects in vivo. Grade: >98%. CAS No. 1600543-88-1. Molecular formula: C196H292N50O56S6. Mole weight: 4437.13. | |
| H-VAL-PHE-OH | It can inhibit angiotensin-1 converting enzyme (ACE) with an IC50 of 9.2 μM. Synonyms: L-valyl-L-phenylalanine; VAL-PHE; valylphenylalanine; L-Val-L-Phe; VF dipeptide; Valine Phenylalanine dipeptide; (S)-2-((S)-2-Amino-3-methyl-butyrylamino)-3-phenyl-propionic acid. CAS No. 3918-92-1. Molecular formula: C14H20N2O3. Mole weight: 264.32. | |
| H-Val-Pro-Pro-OH TFA | H-Val-Pro-Pro-OH TFA is a milk-derived proline peptides derivative. It is an inhibitor of Angiotensin I converting enzyme (ACE), with an IC50 of 9 μM. Synonyms: L-valyl-L-prolyl-L-proline trifluoroacetic acid. Grade: 98%. CAS No. 2828433-08-3. Molecular formula: C17H26F3N3O6. Mole weight: 425.40. | |
| (±)-Hyalodendrin | (±)-Hyalodendrin is an antibiotic produced by Penicillum turbatum. It has anti-gram-positive bacteria and several viral activities. Synonyms: 2,3-Dithia-5,7-diazabicyclo[2.2.2]octane-6,8-dione, 1-(hydroxymethyl)-5,7-dimethyl-4-(phenylmethyl)-; Antibiotic A 26771A; 1-Benzyl-1,4-dimethyl-5-hydroxymethyl-2,5-epi-dithio-3,6-diketopiperazine; 1-(Hydroxymethyl)-5,7-dimethyl-4-(phenylmethyl)-2,3-dithia-5,7-diazabicyclo[2.2.2]octane-6,8-dione; 2-Benzyl-1,4-dimethyl-5-hydroxymethyl-2,5-epi-dithia-3,6-diketopiperazine; 2-Benzyl-1,4-dimethyl-5-hydroxymethyl-2,5-epidithiapiperazine-3,6-dione. Grade: ≥95%. CAS No. 40380-24-3. Molecular formula: C14H16N2O3S2. Mole weight: 324.42. | |
| Hyaluronate biotin - Molecular Weight - 1000kDa | Hyaluronate biotin - Molecular Weight - 1000kDa. | |
| Hyaluronate biotin - Molecular Weight - 10kDa | Hyaluronate biotin - Molecular Weight - 10kDa. | |
| Hyaluronate biotin - Molecular Weight - 1500kDa | Hyaluronate biotin - Molecular Weight - 1500kDa. | |
| Hyaluronate biotin - Molecular Weight - 20kDa | Hyaluronate biotin - Molecular Weight - 20kDa. | |
| Hyaluronate biotin - Molecular Weight - 2500kDa | Hyaluronate biotin - Molecular Weight - 2500kDa. | |
| Hyaluronate biotin - Molecular Weight - 250kDa | Hyaluronate biotin - Molecular Weight - 250kDa. | |
| Hyaluronate biotin - Molecular Weight - 500kDa | Hyaluronate biotin - Molecular Weight - 500kDa. | |
| Hyaluronate biotin - Molecular Weight - 50kDa | Hyaluronate biotin - Molecular Weight - 50kDa. | |
| Hyaluronate biotin - Molecular Weight - 750kDa | Hyaluronate biotin - Molecular Weight - 750kDa. | |
| Hyaluronic acid sodium | Hyaluronic Acid, Sodium Salt is the sodium salt form of Hyaluronic Acid. Hyaluronic acid is a mucopolysaccharide with high-viscosity traditionally extracted from rooster combs, but now it is mainly produced via streptococcal fermentation. Hyaluronic acid exerts physiological effects through skin and mucous membrane absorption, including anti-inflammatory, promoting cell growth and differentiation, promoting wound repair, preventing skin aging, and maintaining its finish. Bioactive hyaluronic acid can be used to make skin and mucous membrane sprays, masks, eye drops, mouthwash, oral and vaginal protectants, etc. It has a broad application prospect. Nutritional supplement in health care products. Uses: Ingredient of health care products. Synonyms: Hyaluronic acid, sodium salt; Arthrease; Artz; Artz Dispo; Artzal; Chlamyhyaluronic acid sodium salt; Cosphaderm; Cristalhyal 1.0; Crystalhyal; Cystistat; Euflexxa; FCH SUS; FCH-SU; Fermatron; HA; HA-F; HA-Q; HA-Q 1; HA-QA; HE-QSE; Healon; Healon (polysaccharide); Healon GV; Healon V; Hi-Aqua; Hyalart; Hyalein; Hyalein Mini; Hyalgan; Hyalonano; Hyaloorigo; Hyaluronan sodium salt; Hyaluronate sodium; Hyaluronic acid LM; Hyaluronic acid sodium salt; Hyasol; Hyladerm; Hylartin; Hylo Comod; Jointex; Khionat; Kynex; Maruha; MucoUp; Nanuo HA; Neoviderm; Nidelon; Opegan; Orthovisc; Ostenil; Provisc; Provisk; Renovhy. CAS No. 9067-32-7. Molecular formula: (C14H22NNaO11)n. | |
| Hydrazide-PEG4-Desthiobiotin | Hydrazide-PEG4-Desthiobiotin is a polyethylene glycol (PEG)-based PROTAC linker. Hydrazide-PEG4-Desthiobiotin can be used in the synthesis of a series of PROTACs. Synonyms: Hydrazide-PEG4-Desthiobiotin; HY-134722; CS-0148310. Grade: >95%. Molecular formula: C21H41N5O7. Mole weight: 475.58. | |
| Hydrogenated Bisphenol A phosphite polymer | Hydrogenated Bisphenol A phosphite polymer. CAS No. 27014-73-9. | |
| Hydrolyzed Fumonisin B1 | Hydrolyzed Fumonisin B1 is the backbone and main hydrolysis product of the mycotoxin Fumonisin B1. Hydrolyzed Fumonisin B1 can weakly inhibit ceramide synthase. Synonyms: AP1 Metabolite; Aminopentol; Aminopentol formate salt; 2-amino-12,16-dimethylicosane-3,5,10,14,15-pentol. Grade: ≥95%. CAS No. 145040-09-1. Molecular formula: C22H47NO5. Mole weight: 405.61. | |
| Hydrolyzed Fumonisin B2 | Hydrolyzed Fumonisin B2 is a metabolite of Fumonisin B2, a mycotoxin produced by mold associated with corn. Synonyms: Fumonisin AP2; Fumonisin HB2; Hydrolyzed Fumonisin B2; 3,?5,?14,?15-Eicosanetetrol, 2-amino-12,?16-dimethyl-, (2S,?3S,?5R,?12S,?14S,?15R,?16R)?-; (2S,3S,5R,12S,14S,15R,16R)-2-Amino-12,16-dimethyl-3,5,14,15-eicosanetetrol. Grade: ≥97%. CAS No. 147985-10-2. Molecular formula: C22H47NO4. Mole weight: 389.61. | |
| Hydroxyfenbendazole-[d3] | Hydroxyfenbendazole-[d3], is the labelled analogue of Hydroxyfenbendazole, which is an impurity of fenbendazole. Synonyms: [5-(4-Hydroxy-phenyl-sulfanyl)-1H-benzo-imidazol-2-yl]-carbamic acid methyl-D3 ester; Hydroxyfenbendazole-D3. Grade: 95% by HPLC; 98% atom D. CAS No. 1596803-40-5. Molecular formula: C15H10D3N3O3S. Mole weight: 318.37. | |
| Hydroxyfenbendazole-[methyl-d3] monohydrate | Hydroxyfenbendazole-[methyl-d3] monohydrate is a labelled analogue of Hydroxyfenbendazole monohydrate, which is used as a radiolabelled internal standard. Synonyms: N-[6-[(4-Hydroxyphenyl)thio]-1H-benzimidazol-2-yl]carbamic acid methyl-d3 ester monohydrate; Hydroxyfenbendazole-D3 hydrate. CAS No. 1596379-07-5. Molecular formula: C15H12D3N3O4S. Mole weight: 336.38. | |
| Hygromycin B | Hygromycin B is an aminoglycoside antibiotic produced by Streptomyces hygroscopicus, Str. noboritoensis and Corynebacterium sp. It has anti-gram-positive bacteria, negative bacteria, mycobacteria, amoeba, spirochetes and anthelmintic effects. Uses: Anthelmintics. Synonyms: Macromycin; O-6-Amino-6-deoxy-L-glycero-D-galacto-heptopyranosylidene-(1→2-3)-O-β-D-talopyranosyl-(1→5)-2-deoxy-N3-methyl-D-streptamine; Antihelmycin; Hygromix 2.4; Hygromix-8; Hygrovetin; Hygrovetine. Grade: >98%. CAS No. 31282-04-9. Molecular formula: C20H37N3O13. Mole weight: 527.52. | |
| Hymeglusin | It is a β-lactone antibiotic produced by the strain of Cephalosporium sp. It has a strong inhibitory effect on hydroxymethyl glutaryl coenzyme A (HMG-CoA) synthase. Synonyms: Hymeglusin; Antibiotic 1233A; 29066-42-0; L-659,699; (2E,4E,7R)-11-[(2R,3R)-3-(hydroxymethyl)-4-oxooxetan-2-yl]-3,5,7-trimethylundeca-2,4-dienoic acid; 2,4-Undecadienoic acid, 11-[(2R,3R)-3-(hydroxymethyl)-4-oxo-2-oxetanyl]-3,5,7-trimethyl-, (2E,4E,7R)-; Antibiotic F 244; (R,R)-Hymeglusin; L 659699; F 244; F-244; SCHEMBL613745; CHEMBL470269; GTPL5886; CHEBI:191049; DTXSID901318499; (R,2E,4E)-11-((2R,3R)-3-(hydroxymethyl)-4-oxooxetan-2-yl)-3,5,7-trimethylundeca-2,4-dienoic acid; HB3701; AKOS032946337; 2,4-Undecadienoic acid, 11-(3-(hydroxymethyl)-4-oxo-2-oxetanyl)-3,5,7-trimethyl-, (2R-(2-alpha(2E,4E,7R*),3-beta))-; HY-117430; CS-0065979; G13092; J-017379; Q27078398; 11-[3R-(hydroxymethyl)-4-oxo-2R-oxetanyl]-3,5,7R-trimethyl-2E,4E-undecadienoic acid. Grade: ≥95%. CAS No. 29066-42-0. Molecular formula: C29H28ClFN6O3. Mole weight: 563. | |
| (Hyp3,β-(2-thienyl)-Ala5,Tyr(Me)8-(R)-Arg9)-Bradykinin | (Hyp3,β-(2-thienyl)-Ala5,Tyr(Me)8-(R)-Arg9)-Bradykinin, a selective bradykinin B2 receptor agonist, has a longer plasma half-life than bradykinin, and transiently increases the blood-brain barrier (BBB) permeability to facilitate drug delivery to the central nervous system. Synonyms: Labradimil; (Hyp3,β-(2-thienyl)-Ala5,Tyr(Me)8-psi(CH2NH)Arg9)-Bradykinin; H-Arg-Pro-Hyp-Gly-β-(2-thienyl)-Ala-Ser-Pro-Tyr(Me)-psi(CH2NH)Arg-OH; Cereport; Lobradimil; RMP-7; (S-(R*,R*))-L-Arginyl-L-prolyl-trans-4-hydroxy-L-prolyl-3-(2-thienyl)-L-alanylglycyl-L-seryl-N-(2-((4-((aminoiminomethyl)amino)-1-carboxybutyl)amino)-1-((4-methoxyphenyl)methyl)ethyl)-L-prolinamide; N2-((S)-2-(L-Arginyl-L-prolyl-trans-4-hydroxy-L-prolylglycyl-3-(2-thienyl)-L-alanyl-L-seryl-L-prolinamido)-3-(p-methoxyphenyl)propyl)-L-arginine. Grade: 95%. CAS No. 159768-75-9. Molecular formula: C49H75N15O12S. Mole weight: 1098.28. | |
| Hypercalcemia of malignancy factor fragment 1-34 amide human | Hypercalcemia of malignancy factor fragment 1-34 amide is an extraordinary biomedical innovation exhibiting remarkable potential in the research of hypercalcemia linked to malignancies. Synonyms: Hypercalcemia of Malignancy Factor (1-34) amide (human, mouse, rat); H-Ala-Val-Ser-Glu-His-Gln-Leu-Leu-His-Asp-Lys-Gly-Lys-Ser-Ile-Gln-Asp-Leu-Arg-Arg-Arg-Phe-Phe-Leu-His-His-Leu-Ile-Ala-Glu-Ile-His-Thr-Ala-NH2; pTH-Related Protein (1-34) amide (human, mouse, rat); L-alanyl-L-valyl-L-seryl-L-alpha-glutamyl-L-histidyl-L-glutaminyl-L-leucyl-L-leucyl-L-histidyl-L-alpha-aspartyl-L-lysyl-glycyl-L-lysyl-L-seryl-L-isoleucyl-L-glutaminyl-L-alpha-aspartyl-L-leucyl-L-arginyl-L-arginyl-L-arginyl-L-phenylalanyl-L-phenylalanyl-L-leucyl-L-histidyl-L-histidyl-L-leucyl-L-isoleucyl-L-alanyl-L-alpha-glutamyl-L-isoleucyl-L-histidyl-L-threonyl-L-alaninamide; PTHrP (1-34) amide. Grade: 95%. CAS No. 112955-31-4. Molecular formula: C180H288N58O47. Mole weight: 4016.57. | |
| Iberiotoxin | Iberiotoxin, a toxin extracted from the venom of the scorpion Buthus tamulus, is a selective blocker of high-conductance Ca2+-activated K+ channel. Synonyms: Pyr-Phe-Thr-Asp-Val-Asp-Cys-Ser-Val-Ser-Lys-Glu-Cys-Trp-Ser-Val-Cys-Lys-Asp-Leu-Phe-Gly-Val-Asp-Arg-Gly-Lys-Cys-Met-Gly-Lys-Lys-Cys-Arg-Cys-Tyr-Gln-OH (Disulfide bridge: Cys7-Cys28, Cys13-Cys33, Cys17-Cys35); 5-Oxo-L-prolyl-L-phenylalanyl-L-threonyl-L-α-aspartyl-L-valyl-L-α-aspartyl-L-cysteinyl-L-seryl-L-valyl-L-seryl-L-lysyl-L-α-glutamyl-L-cysteinyl-L-tryptophyl-L-seryl-L-valyl-L-cysteinyl-L-lysyl-L-α-aspartyl-L-leucyl-L-phenylalanylglycyl-L-valyl-L-α-aspartyl-L-arginylglycyl-L-lysyl-L-cysteinyl-L-methionylglycyl-L-lysyl-L-lysyl-L-cysteinyl-L-arginyl-L-cysteinyl-L-tyrosyl-L-glutamine cyclic (7→28),(13→33),(17→35)-tris(disulfide); 4-L-aspartic acid-6-L-aspartic acid-8-L-serine-9-L-valine-18-L-lysine-19-L-aspartic acid-21-L-phenylalanine-22-glycine-23-L-valine-24-L-aspartic acid-30-glycine-37-L-glutamine-charybdotoxin. Grade: ≥96% by HPLC. CAS No. 129203-60-7. Molecular formula: C179H274N50O55S7. Mole weight: 4230.85. | |
| Ibrutinib-biotin | Ibrutinib-biotin is a probe that consists of Ibrutinib connected to biotin via a long chain linker with an IC50 of 0.755-1.02 nM for BTK. (Extracted from patent WO2014059368A1 Compound 1-5). Synonyms: Ibrutinib-biotin-1; N-(4-{[(2E)-4-{(3R)-3-[4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl}-4-oxo-2-buten-1-yl](methyl)amino}butyl)-N'-{15-oxo-19-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]-4,7,10-trioxa-14-azanonadec-1-yl}pentanediamide. Grade: ≥98%. CAS No. 1599432-18-4. Molecular formula: C56H80N12O9S. Mole weight: 1097.37. | |
| (±)-Ibuprofen-[d3] Sodium Salt | (±)-Ibuprofen-[d3] Sodium Salt is the labelled analogue of (±)-Ibuprofen Sodium salt, which could be used as a nonsteroidal anti-inflammatory. Synonyms: (±)-Ibuprofen-d3, Sodium Salt (α-methyl-d3); α-Methyl-4-(isobutyl)phenylacetic Acid-d3, Sodium Salt. Grade: 95% by HPLC; 98% atom D. CAS No. 1219805-09-0. Molecular formula: C13H14D3NaO2. Mole weight: 231.28. | |
| Icatibant | Icatibant(HOE-140) is a selective and specific antagonist of bradykinin B2 receptor with IC50 and Ki of 1.07 nM and 0.798 nM respectively. Uses: Anti-inflammatory agents, non-steroidal. Synonyms: L-Arginine, D-arginyl-L-arginyl-L-prolyl-(4R)-4-hydroxy-L-prolylglycyl-3-(2-thienyl)-L-alanyl-L-seryl-(3R)-1,2,3,4-tetrahydro-3-isoquinolinecarbonyl-(2S,3aS,7aS)-octahydro-1H-indole-2-carbonyl-; H-D-Arg-Arg-Pro-Hyp-Gly-2Thi-Ser-D-Tic-Oic-Arg-OH; D-Arginyl-L-arginyl-L-prolyl-(4R)-4-hydroxy-L-prolylglycyl-3-(2-thienyl)-L-alanyl-L-seryl-(3R)-1,2,3,4-tetrahydro-3-isoquinolinecarbonyl-(2S,3aS,7aS)-octahydro-1H-indole-2-carbonyl-L-arginine; HOE140; HOE 140; HOE-140. Grade: >98%. CAS No. 130308-48-4. Molecular formula: C59H89N19O13S. Mole weight: 1304.52. | |
| Icatibant Acetate | Icatibant acetate is a selective antagonist of bradykinin B2 receptors. Icatibant is a medication approved for the treatment of acute attacks of hereditary angioedema (HAE) in adults with C1-esterase-inhibitor deficiency. Uses: Anti-inflammatory agents, non-steroidal. Synonyms: HOE 140 Acetate; HOE140 Acetate; HOE-140 Acetate; L-Arginine, D-arginyl-L-arginyl-L-prolyl-(4R)-4-hydroxy-L-prolylglycyl-3-(2-thienyl)-L-alanyl-L-seryl-(3R)-1,2,3,4-tetrahydro-3-isoquinolinecarbonyl-(2S,3aS,7aS)-octahydro-1H-indole-2-carbonyl-, acetate (1:x); H-D-Arg-Arg-Pro-Hyp-Gly-2Thi-Ser-D-Tic-Oic-Arg-OH.CH3CO2H; L-Arginine, D-arginyl-L-arginyl-L-prolyl-trans-4-hydroxy-L-prolylglycyl-3-(2-thienyl)-L-alanyl-L-seryl-D-1,2,3,4-tetrahydro-3-isoquinolinecarbonyl-L-(2α,3aβ,7aβ)-octahydro-1H-indole-2-carbonyl-, acetate (salt); Firazyr. Grade: ≥95%. CAS No. 138614-30-9. Molecular formula: C59H89N19O13S.xC2H4O2. Mole weight: 1304.52 (free base). | |
| ICI 154,129 | ICI 154,129 is a selective δ opioid antagonist. It is a peptide analog that antagonized the effects of Leu-enkephalin. Uses: Narcotic antagonists. Synonyms: N,N-Di(2-propenyl)-L-Tyr-N-[2-[[(S)-2-[[(S)-1-carboxy-3-methylbutyl]amino]-2-oxo-1-benzylethyl]thio]ethyl]-Gly-NH2; M-154129. Grade: >98%. CAS No. 83420-94-4. Molecular formula: C34H46N4O6S. Mole weight: 638.83. | |
| ICI 174,864 | ICI 174,864 is a potent and highly selective δ opioid antagonist. It shows partial agonist in vitro activity at δ receptors at high concentrations. Synonyms: ICI 174,864; ICI174,864; ICI-174,864; N,N-Di-2-propen-1-yl-L-tyrosyl-2-methylalanyl-L-phenylalanyl-L-leucine; NIH 10893; N,N-diallyl-tyrosyl-alpha-aminoisobutyric acid-phenylalanyl-leucine; L-Leucine, N-(N-(N-(N,N-di-2-propenyl-L-tyrosyl)-2-methylalanyl)-L-phenylalanyl)-; N,N-Diallyl-Tyr-aib-Phe-Leu. Grade: >98%. CAS No. 89352-67-0. Molecular formula: C38H53N5O7. Mole weight: 691.87. | |
| Icotinib hydrochloride | Icotinib Hydrochloride is a quinazoline-based inhibitor of epidermal growth factor receptor (EGFR), which is upregulated in a variety of cancer cell types. Icotinib supresses the cancer cell proliferation via EGFR tyrosine kinase inhibition. Synonyms: Icotinib HCl; BPI-2009; BPI 2009; BPI2009. Grade: >98%. CAS No. 1204313-51-8. Molecular formula: C22H22ClN3O4. Mole weight: 427.88. | |
| IGF-I 24-41 | IGF-I 24-41 is a 24-41 amino acid fragment of insulin-like growth factor I(IGF-I). IGF-I has anabolic, antioxidant, anti-inflammatory and cell-protective properties. Synonyms: Insulin-like Growth Factor I (24-41); H-Tyr-Phe-Asn-Lys-Pro-Thr-Gly-Tyr-Gly-Ser-Ser-Ser-Arg-Arg-Ala-Pro-Gln-Thr-OH; L-tyrosyl-L-phenylalanyl-L-asparagyl-L-lysyl-L-prolyl-L-threonyl-glycyl-L-tyrosyl-glycyl-L-seryl-L-seryl-L-seryl-L-arginyl-L-arginyl-L-alanyl-L-prolyl-L-glutaminyl-L-threonine. Grade: ≥95%. CAS No. 135861-49-3. Molecular formula: C88H133N27O28. Mole weight: 2017.16. | |
| IGF-I 30-41 | IGF-I 30-41 is a 30-41 amino acid fragment of insulin-like growth factor I(IGF-I). IGF-I has anabolic, antioxidant, anti-inflammatory and cell-protective properties. Synonyms: Insulin-like Growth Factor I (30-41); H-Gly-Tyr-Gly-Ser-Ser-Ser-Arg-Arg-Ala-Pro-Gln-Thr-OH; glycyl-L-tyrosyl-glycyl-L-seryl-L-seryl-L-seryl-L-arginyl-L-arginyl-L-alanyl-L-prolyl-L-glutaminyl-L-threonine. Grade: ≥95%. CAS No. 82177-09-1. Molecular formula: C51H83N19O19. Mole weight: 1266.32. | |
| IGF-I 30-41 acetate | IGF-I 30-41 acetate is a 30-41 amino acid fragment of insulin-like growth factor I(IGF-I). IGF-I has anabolic, antioxidant, anti-inflammatory and cell-protective properties. Synonyms: Insulin-like Growth Factor I (30-41) acetate; H-Gly-Tyr-Gly-Ser-Ser-Ser-Arg-Arg-Ala-Pro-Gln-Thr-OH.CH3CO2H; glycyl-L-tyrosyl-glycyl-L-seryl-L-seryl-L-seryl-L-arginyl-L-arginyl-L-alanyl-L-prolyl-L-glutaminyl-L-threonine acetic acid. Grade: ≥95%. Molecular formula: C53H87N19O21. Mole weight: 1326.39. | |
| IGF-I Analog | The IGF-I peptide analog was able to inhibit the autophosphorylation of the IGF-I receptor by IGF-I as well as the growth of several different cell types, including prostate carcinoma cells and SV40-transformed cells. Synonyms: JB-1 peptide; Cys-Tyr-Ala-Ala-Pro-Leu-Lys-Pro-Ala-Lys-Ser-Cys disulfide. Grade: 95%. CAS No. 147819-32-7. Molecular formula: C55H88N14O15S2. Mole weight: 1249.5. | |
| Ikarugamycin | An unusual pentacyclic tetramic acid produced by streptomyces phaeochromogenes; potent activity against the protozoan, trichomonas vaginalis; demonstrates selective gram positive antibacterial activity, and anti-ulcer activity possibly via inhibition of H. Pylori; inhibits the uptake of oxidized low-density lipoprotein in mouse macrophages, blocks PMA and nef-mediated cell surface CD4 down-regulation, and inhibits clathrin-coated pit-mediated endocytosis; a useful agent for studying the process of endocytosis. Synonyms: 14,17-Metheno-17H-as-indaceno[3,2-k][1,6]diazacycloheptadecine-9,16,18(1H)-trione. Grade: >99% by HPLC. CAS No. 36531-78-9. Molecular formula: C29H38N2O4. Mole weight: 478.62. | |
| IL-10 Protein, Human (Biotinylated, HEK293, His-Avi) | Interleukin 10 (IL-10), also known as human cytokine synthesis inhibitory factor (CSIF), is a cytokine with potent and broad-spectrum anti-inflammatory properties. IL-10 inhibits the production of pro-inflammatory cytokines and the activation of Th1 and Th2 cells. IL-10 maintains the balance of the immune response, allowing for the clearance of infection while minimizing damage to the host. IL-10 can inhibit the pro-inflammatory response of innate and adaptive immune cells. Synonyms: Interleukin-10; IL-10; CSIF; IL10A; TGIF; B-TCGF; GVHDS; MGC126450; MGC126451. Grade: ≥95%. Mole weight: 23-25 kDa. | |
| IL-12 Protein, Human (Biotinylated, HEK293, His) | Interleukin 12 (IL-12) is an interleukin that is naturally produced by dendritic cells, macrophages, neutrophils, and human B-lymphoblastoid cells (NC-37) in response to antigenic stimulation. IL-12 belongs to the Interleukin-12 family, which is unique in comprising only heterodimeric cytokines. IL-12 acts as a growth factor for activated T and NK cells, enhances the lysate activity of natural killer cells or lymphokine-activated killer cells, and stimulates IFN-γ production through resting PBMC. IL-12 also has anti-angiogenic activity. IL-12 Protein, Human (Biotinylated, HEK293, His) is a biotinylated protein, produced in HEK293 cells with His-tag. Synonyms: IL-12; Interleukin 12; Interleukin-12 subunit alpha; IL-12A; Cytotoxic lymphocyte maturation factor 35 kDa subunit; CLMF p35; IL-12 subunit p35; Interleukin-12 subunit beta; IL-12B; Cytotoxic lymphocyte maturation factor 40 kDa subunit; CLMF p40; IL-12 subunit p40. Grade: ≥95%. Mole weight: ~24&36.2 kDa. | |
| IL-12 Protein, Human (Biotinylated, HEK293, His-Avi) | Interleukin 12 (IL-12) is an interleukin that is naturally produced by dendritic cells, macrophages, neutrophils, and human B-lymphoblastoid cells (NC-37) in response to antigenic stimulation. IL-12 belongs to the Interleukin-12 family, which is unique in comprising only heterodimeric cytokines. IL-12 acts as a growth factor for activated T and NK cells, enhances the lysate activity of natural killer cells or lymphokine-activated killer cells, and stimulates IFN-γ production through resting PBMC. IL-12 also has anti-angiogenic activity. IL-12 Protein, Human (Biotinylated, HEK293, His-Avi) is a biotinylated protein, produced in HEK293 cells with His-tag and Avi-tag. Synonyms: CLMF; CLMF2; IL-12A; IL-12B; IL12; IL12 p70; IMD28; IMD29; NFSK; NKSF1; NKSF2; P35; IL-12 subunit p35; IL12A; Interleukin 12. Grade: ≥95%. Mole weight: ~40-45 kDa. | |
| IL-13 Protein, Human (Biotinylated, HEK293, Avi-His) | Interleukin-13 (IL-13) is an immunoregulatory cytokine secreted by T helper type 2 (Th2) cells, CD4 cells, natural killer T cells, mast cells, basophils, eosinophils, and nuocytes. IL-13 is a central regulator in IgE synthesis, goblet cell hyperplasia, mucus hypersecretion, airway hyperresponsiveness, fibrosis, and chitinase up-regulation. IL-13 recognizes IL-13/4R and IL-13Ra2 receptors, has anti-inflammatory effects on monocytes and macrophages, and inhibits the expression of inflammatory cytokines IL-1β, TNF-α, IL-6, and IL-8. IL-13 is a mediator of allergic inflammation and different diseases including asthma. Synonyms: Interleukin-13; IL-13. Grade: ≥95%. Mole weight: 22-35 kDa. | |
| IL-15R alpha & IL-15 Protein, Human (Biotinylated, HEK293, His) | Interleukin-15 (IL-15) is an inflammatory cytokine that stimulates the expression of tumor necrosis factor α (TNF-α), IL-1β, and inflammatory chemokines. IL-15 is secreted primarily by monocytes and macrophages, which are activated by the products of viral or bacterial infections. IL-15 binds and signals through a trimetric receptor consisting of a common gamma chain, IL-2Rβ, and IL-15Rα. Similar to IL-2, IL-15 triggers the proliferation of normal B lymphocytes and the production of immunoglobulins. IL-15Rα/IL-15 complex can activate the anti-tumor function of NK cells and CD8+ T cells. IL-15R alpha & IL-15 Protein, Human (Biotinylated, HEK293, His), produced in HEK293 cells, is a recombinant biotinylated human IL-15Rα (I31-S108) and IL-15 (N49-S162) fusion protein with His-tag. Synonyms: IL-15 R alpha; CD215; IL15RA; IL-15RA; IL-15R-alpha1; Interleukin-15; IL-15; IL15. Grade: ≥95%. Mole weight: 25-28 kDa. | |
| IL-17A-17F Heterodimer Protein, Human (Biotinylated, HEK293, His-Avi) | IL-17A-17F heterodimer protein is a heterodimer of the cytokines IL-17A and IL-17F, and its biological activity is between IL-17A and IL-17F. Both IL-17A and IL-17F can induce the production of antimicrobial peptides (defensins and S100 proteins), cytokines (IL-6, G-CSF, and GM-CSF), chemokines (CXCL1, CXCL5, IL-8, CCL2, and CCL7), and matrix metalloproteinases (MMP1, MMP3, and MMP13). IL-17A-17F Heterodimer Protein, Human (Biotinylated, HEK293, His-Avi), composed of 265 amino acids (IL-17A (G24-A155) and IL-17F (R31-Q163)), is a biotinylated recombinant human IL-17A-17F heterodimer protein expressed in HEK293 cells with His tag and Avi tag. Synonyms: IL-17A; Interleukin-17A; CTLA-8; IL-17; IL-17F; IL24; ML-1; Interleukin-17F. Grade: ≥95%. Mole weight: ~16 kDa. | |
| IL-17A-17F Heterodimer Protein, Mouse (Biotinylated, HEK293, His-Avi) | IL-17A-17F heterodimer protein is a heterodimer of the cytokines IL-17A and IL-17F, and its biological activity is between IL-17A and IL-17F. Both IL-17A and IL-17F can induce the production of antimicrobial peptides (defensins and S100 proteins), cytokines (IL-6, G-CSF, and GM-CSF), chemokines (CXCL1, CXCL5, IL-8, CCL2, and CCL7), and matrix metalloproteinases (MMP1, MMP3, and MMP13). IL-17A-17F Heterodimer Protein, Mouse (Biotinylated, HEK293, His-Avi), composed of 266 amino acids (IL-17A (A26-A158) and IL-17F (R29-A161)), is a biotinylated recombinant mouse IL-17A-17F heterodimer protein expressed in HEK293 cells with His tag and Avi tag. Synonyms: IL-17A; Interleukin-17A; CTLA-8; IL-17; IL-17F; IL24; ML-1; Interleukin-17F. Grade: ≥95%. Mole weight: 22-25&27-30 kDa. | |
| IL-17A Protein, Human (Biotinylated, 132a.a, HEK293, His-Avi) | Interleukin 17 (IL-17) family is a family of pro-inflammatory cystine node cytokines consisting of IL17A, IL17B, IL17C, IL17D, IL17E, and IL17F. IL-17A is a homodimer factor that plays a key role in host defense mechanisms against many bacterial and fungal pathogens, as well as allergic and autoimmune responses. IL-17A induces the production of antimicrobial peptides (defensins and S100 proteins), cytokines (IL-6, G-CSF, and GM-CSF), chemokines (CXCL1, CXCL5, IL-8, CCL2, and CCL7), and matrix metalloproteinases (MMP1, MMP3, and MMP13). IL-17A Protein, Human (Biotinylated, 132a.a, HEK293, His-Avi), composed of 132 amino acids (G24-A155), is a biotinylated recombinant human IL-17A protein expressed in HEK293 cells with His tag and Avi tag. Synonyms: CTLA-8; IL17; IL17A; IL-17CTLA-8; Interleukin 17A. Grade: ≥95%. Mole weight: 16-30 kDa. | |
| IL-17A Protein, Mouse (Biotinylated, HEK293, His-Avi) | Interleukin 17 (IL-17) family is a family of pro-inflammatory cystine node cytokines consisting of IL17A, IL17B, IL17C, IL17D, IL17E, and IL17F. IL-17A is a homodimer factor that plays a key role in host defense mechanisms against many bacterial and fungal pathogens, as well as allergic and autoimmune responses. IL-17A induces the production of antimicrobial peptides (defensins and S100 proteins), cytokines (IL-6, G-CSF, and GM-CSF), chemokines (CXCL1, CXCL5, IL-8, CCL2, and CCL7), and matrix metalloproteinases (MMP1, MMP3, and MMP13). IL-17A Protein, Mouse (Biotinylated, HEK293, His-Avi), composed of 133 amino acids (A26-A158), is a biotinylated recombinant mouse IL-17A protein expressed in HEK293 cells with His tag and Avi tag. Synonyms: CTLA-8; IL17; IL17A; IL-17CTLA-8; Interleukin 17A. Grade: ≥95%. Mole weight: 20-28 kDa. | |
| IL-17C Protein, Human (Biotinylated, HEK293, His-Avi) | Interleukin 17 (IL-17) family is a family of pro-inflammatory cystine node cytokines consisting of IL17A, IL17B, IL17C, IL17D, IL17E, and IL17F. IL-17C is predominantly expressed by epithelial cells and is produced by cells expressing Chromogranin A (enteroendocrine cells) and mucin (goblet cells). IL-17C is an early response cytokine in bacterial pathogen defense and upregulates the expression of a variety of antimicrobial peptides, including human beta-defensin 2 (hBD2), Lipocalin 2 (LCN2), and granzyme b. IL-17C stimulates the release of cytokines (IL-1β, TNF-α, and IL-6), and is implicated in autoimmune disorders and bacterial infections. IL-17C Protein, Human (Biotinylated, HEK293, His-Avi), composed of 179 amino acids (H19-V197), is a biotinylated recombinant human IL-17C protein expressed in HEK293 cells with His tag and Avi tag. Synonyms: CX2; Cytokine CX2; IL17C; IL-17; CMGC126884; Interleukin 17C; Interleukin-17C. Grade: ≥90%. Mole weight: 24-26 kDa. | |
| IL-17F Protein, Human (Biotinylated, HEK293, His-Avi) | Interleukin 17 (IL-17) family is a family of pro-inflammatory cystine node cytokines consisting of IL17A, IL17B, IL17C, IL17D, IL17E, and IL17F. IL-17F induces the expression of a variety of pro-inflammatory cytokines and chemokines. IL-17F signaling can lead to the production of antimicrobial peptides and matrix metalloproteinases. IL-17F signaling activates the MAP kinase pathway, leading to the activation of NF-κB, MAPK-AP-1, and C/EBP. IL-17F is a proinflammatory homodimer factor associated with many diseases, including psoriasis, ankylosing spondylitis, asthma and allergic airway inflammation, intestinal inflammation, and cancer. IL-17F Protein, Human (Biotinylated, HEK293, His-Avi), composed of 133 amino acids (R31-Q163), is a biotinylated recombinant human IL-17F protein expressed in HEK293 cells with His tag and Avi tag. Synonyms: Cytokine ML-1; IL17F; IL-17F; IL24; IL-24; CANDF6; IL-17F; ML1. Grade: ≥95%. Mole weight: 23-28 kDa. | |
| IL-17F Protein, Mouse (Biotinylated, HEK293, His-Avi) | Interleukin 17 (IL-17) family is a family of pro-inflammatory cystine node cytokines consisting of IL17A, IL17B, IL17C, IL17D, IL17E, and IL17F. IL-17F induces the expression of a variety of pro-inflammatory cytokines and chemokines. IL-17F signaling can lead to the production of antimicrobial peptides and matrix metalloproteinases. IL-17F signaling activates the MAP kinase pathway, leading to the activation of NF-κB, MAPK-AP-1, and C/EBP. IL-17F is a proinflammatory homodimer factor associated with many diseases, including psoriasis, ankylosing spondylitis, asthma and allergic airway inflammation, intestinal inflammation, and cancer. IL-17F Protein, Mouse (Biotinylated, HEK293, His-Avi), composed of 133 amino acids (R29-A161), is a biotinylated recombinant mouse IL-17F protein expressed in HEK293 cells with His tag and Avi tag. Synonyms: Cytokine ML-1; IL17F; IL-17F; IL24; IL-24; CANDF6; IL-17F; ML1. Grade: ≥95%. Mole weight: 30-35 kDa. | |
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