BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
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LHRH II
LHRH II, first found in chicken, is highly conserved in vertebrates. Synonyms: LH-RH II, chicken; Pyr-His-Trp-Ser-His-Gly-Trp-Tyr-Pro-Gly-NH2; LHRH, His(5)-Trp(7)-Tyr(8)-; Glycinamide, 5-oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-histidylglycyl-L-tryptophyl-L-tyrosyl-L-prolyl-; 5-Oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-histidylglycyl-L-tryptophyl-L-tyrosyl-L-prolylglycinamide; L-pyroglutamyl-L-histidyl-L-tryptophyl-L-seryl-L-histidyl-glycyl-L-tryptophyl-L-tyrosyl-L-prolyl-glycinamide; GNRH, Chicken II; pGlu-His-Trp-Ser-His-Gly-Trp-Tyr-Pro-Gly-NH2; 5-Histidyl-7-tryptophyl-8-tyrosine-LHRH; Luteinizing hormone-releasing factor II (chicken); cGnRH II. Grade: ≥95%. CAS No. 91097-16-4. Molecular formula: C60H69N17O13. Mole weight: 1236.32.
Lignin, alkali can be used as a surface treatment agent for composites of natural fibers with petroleum based resins. It can be used as a biosorbent for potential applications in removing toxic metal ions from wastewater. Synonyms: Alkali lignin; Alkali soluble lignin; Amallin A; Biochoice; Curan (lignin); Eucalin; Kraft lignin; Lignin, kraft; Lignin, soda; Lignin, sulfate; Lignoboost; Lineo; Lineo Classic; Meadol MRM; MG 3 (lignin); Mousoudake Souda Rigunin; Protobind 1000; Soda lignin; Sulfate lignin; Sulphate lignin; Tomlinite. CAS No. 8068-5-1.
LIGNIN, ALKALI, 2-HYDROXYPROPYL ETHER
LIGNIN, ALKALI, 2-HYDROXYPROPYL ETHER. Grade: 95%. CAS No. 88402-77-1.
Lignin Peroxidase. Synonyms: LiP; Ligninase; Peroxidase; lignin. CAS No. 42613-30-9.
Lignin, sodium salt
Lignin, sodium salt. CAS No. 37203-80-8.
Lignin,Willstatter
Lignin,Willstatter. Grade: 95%. CAS No. 8068-11-9.
Linaclotide
Linaclotide is a peptide agonist of guanylate cyclase 2C that is undergoing clinical trials for use in treating abdominal pain in patients with irritable bowel syndrome (IBS) accompanied by constipation. The drug also has promising outlooks for the treatment of gastroparesis, ulcerative colitis, chronic intestinal pseudo-obstruction (CIPO), and inertia coli as well. Synonyms: Constella; Linzess; L-Tyrosine, L-cysteinyl-L-cysteinyl-L-α-glutamyl-L-tyrosyl-L-cysteinyl-L-cysteinyl-L-asparaginyl-L-prolyl-L-alanyl-L-cysteinyl-L-threonylglycyl-L-cysteinyl-, cyclic (1→6),(2→10),(5→13)-tris(disulfide); L-cysteinyl-L-cysteinyl-L-α-glutamyl-L-tyrosyl-L-cysteinyl-L-cysteinyl-L-asparagyl-L-prolyl-L-alanyl-L-cysteinyl-L-threonyl-glycyl-L-cysteinyl-L-tyrosine (1->6),(2->10),(5->13)-tris(disulfide); H-Cys-Cys-Glu-Tyr-Cys-Cys-Asn-Pro-Ala-Cys-Thr-Gly-Cys-Tyr-OH (Disulfide bridge: Cys1-Cys6, Cys2-Cys10, Cys5-Cys13). Grade: ≥95%. CAS No. 851199-59-2. Molecular formula: C59H79N15O21S6. Mole weight: 1526.74.
Lincomycin
It is produced by the strain of Str. lincolnensis var. lincolnensis NRRL 2936. It's a sugar antibiotic. It has anti-gram-positive bacteria and spirochete effect, and has weak antibacterial effect on some gram-negative bacteria. It can protect mice infected with Staphylococcus aureus, Streptococcus hemolyticus and dicoccus pneumoniae by oral or subcutaneous injection. It also has effect on leptospira in vivo. Uses: Anti-bacterial agents. Synonyms: (2S-trans)-Methyl 6,8-Dideoxy-6-[[(1-methyl-4-propyl-2-pyrrolidinyl)carbonyl]amino]-1-thio-D-erythro-α-D-galacto-octopyranoside; Lincocin; Lincogap; Clindamycin Phosphate EP Impurity A; Clindamycin hydrochloride EP Impurity A. Grade: >99% by HPLC. CAS No. 154-21-2. Molecular formula: C18H34N2O6S. Mole weight: 406.54.
Lincomycin hydrochloride
Lincomycin hydrochloride is produced by the strain of Str. lincolnensis var. lincolnensis NRRL 2936. It's a sugar antibiotic. It has anti-gram-positive bacteria and spirochete effect, and has weak antibacterial effect on some gram-negative bacteria. It can protect mice infected with Staphylococcus aureus, Streptococcus hemolyticus and dicoccus pneumoniae by oral or subcutaneous injection. It also has effect on leptospira in vivo. It can prevent and treat respiratory diseases, such as Haemophilus parasuis, infectious pleuropneumonia, mycoplasmosis, atrophic rhinitis, etc. Synonyms: (2S-trans)-Methyl 6,8-Dideoxy-6-[[(1-methyl-4-propyl-2-pyrrolidinyl)carbonyl]amino]-1-thio-D-erythro-α-D-galactooctopyranoside Hydrochloride; trans-α-Methyl 6,8-dideoxy-6-(1-methyl-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-D-erythro-D-galacto-Octopyranoside Monohydrochloride; Lincocin; Lincogap; NSC 70731; U 10149a. Grade: >98%. CAS No. 859-18-7. Molecular formula: C18H35ClN2O6S. Mole weight: 443.00.
Linezolid
Linezolid inhibits initiation complex formation with either the 30S or the 70S ribosomal subunits from Escherichia coli. Linezolid is a synthetic oxazolidinone antibiotic active against a wide range of Gram-positive bacteria, including resistant strains of several species, such as MRSA and penicillin-resistant pneumococci. Synonyms: Zyvox; Zyvoxid; Zyvoxam; PNU 100766; PNU-100766; PNU100766; U 100766; U-100766; U100766. Grade: >98%. CAS No. 165800-03-3. Molecular formula: C16H20FN3O4. Mole weight: 337.35.
Link-EZ Iodoacetyl-PEG2-Biotin
Link-EZ Iodoacetyl-PEG2-Biotin is a cell-impermeant, thiol-reactive biotinylation reagent with increased water solubility. It is conjugated with peptides, antibodies, and other thiol-containing biomolecules. Molecular formula: C18H31IN4O5S. Mole weight: 542.43.
Link-EZ NHS-Desthiobiotin
Link-EZ NHS-Desthiobiotin is a membrane-permeable fluorescent probe suitable for intracellular protein labeling, detection and isolation. Synonyms: d-Desthiobiotin, SE. Molecular formula: C13H19N3O5. Mole weight: 297.31.
Liothyronine Sodium
Liothyronine Sodium is the most potent form of thyroid hormone acting on the body to increase the basal metabolic rate, affect protein synthesis. Synonyms: Cytomel; Triostat; 3,3',5-Triiodo-L-Thyronine Sodium Salt. Grade: ≥ 98% (HPLC). CAS No. 55-06-1. Molecular formula: C15H11I3NO4.Na. Mole weight: 672.96.
Lipoamide-PEG-Biotin, MW 1K-5K
Lipoamide-PEG-Biotin, MW 1,000 is a lipoic acid polyPEG which can bind to metallic surface through disulfide bond. The PEG derivative can be used for biotinylation due to its strong binding with avidin/streptavidin. Please contact us for GMP-grade inquiries.
Lipomycin α
It is produced by the strain of Str. aureofaciens Tu117. It has strong activity of anti-gram-positive bacterial and no activity against fungi (including yeast). Synonyms: alpha-Lipomycin; 4-[13-[(2,6-Dideoxy-beta-D-ribo-hexopyranosyl)oxy]-10,12,14-trimethyl-1-oxopentadeca-2,4,6,8,10-pentenyl]-2,5-dihydro-3-hydroxy-1-methyl-5-oxo-1H-pyrrole-2-propanoic acid. Grade: >95% by HPLC. CAS No. 51053-40-8. Molecular formula: C32H45NO9. Mole weight: 587.70.
Lipstatin
Lipstatin, a potent inhibitor of the pancreas lipase, is reported to be useful in the treatment and prevention of obesity and related diseases. It is a natural product that was first isolated from Actinobacterium Streptomyces toxytricini. Synonyms: N-Formyl-L-leucine (1S,3Z,6Z)-1-[[(2S,3S)-3-Hexyl-4-oxo-2-oxetanyl]methyl]-3,6-dodecadien-1-yl Ester; N-Formyl-L-leucine [2S-[2α(1R*,3Z,6Z),3β]]-1-[(3-Hexyl-4-oxo-2-oxetanyl)methyl]-3,6-dodecadienyl Ester; (-)-Lipstatin. Grade: >95%. CAS No. 96829-59-3. Molecular formula: C29H49NO5. Mole weight: 491.70.
Liraglutide
Liraglutide is the long-acting analogue of glucagon-like peptide-1 (GLP-1) receptor which could protect b-cells from apoptosis under conditions associated with the development of type 1 and type 2 diabetes. Synonyms: L-Histidyl-L-alanyl-L-α-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-valyl-L-seryl-L-seryl-L-tyrosyl-L-leucyl-L-α-glutamylglycyl-L-glutaminyl-L-alanyl-L-alanyl-N6-[N-(1-oxohexadecyl)-L-γ-glutamyl]-L-lysyl-L-α-glutamyl-L-pheny. Grade: > 95%. CAS No. 204656-20-2. Molecular formula: C172H265N43O51. Mole weight: 3751.20.
(+/-)-Lisofylline-[d6]
(+/-)-Lisofylline-[d6] is the labelled analogue of (+/-)-Lisofylline, which is a major oxidative metabolite of Pentoxifylline. Pentoxifylline is a potent inhibitor of phosphatidic acid generation. Synonyms: Lisofylline-D6; (+/-)-Lisofylline-d6; 3,7-Dihydro-1-(5-hydroxyhexyl)-3,7-(dimethyl-d6)-1H-purine-2,6-dione; 1-(5-Hydroxyhexyl)theobromine-d6; (+/-)-1-(5-Hydroxyhexyl)-3,7-(dimethyl-d6)xanthine; Pentoxifylline-d6 Alcohol; Hydroxypentoxifylline-d6. Grade: ≥98% by HPLC; ≥99% atom D. CAS No. 1185995-26-9. Molecular formula: C13H14D6N4O3. Mole weight: 286.37.
Lividomycin A
It is produced by the strain of Str. lividus 2230-N. It's an aminoglycoside antibiotic. It has a broad-spectrum effect against bacteria and mycobacterium, and has no cross-resistance with Streptomyces and penicillium, and has protective effect on mice infected with S. aureus and Pseudomonas aeruginosa. Synonyms: Antibiotic 2230-B; Antibiotic SF-767A; Antibiotic 503-2; D-Streptamine, O-2-Amino-2,3-Dideoxy-A-D-Ribo-Hexopyranosyl-14-O-[O-A-D-Mannopyranosyl-14-O-2,6-Diamino-2,6-Dideoxy-B-L-Idopyranosyl-13-B-D-Ribofuranosyl-15]-2-Deoxy-; Quintomycin B. Grade: 95%. CAS No. 36441-41-5. Molecular formula: C29H55N5O18. Mole weight: 761.77.
Lixisenatide
Lixisenatide is a glucagon-like peptide-1 (GLP-1) receptor agonist that can be used in the treatment of type 2 diabetes mellitus (T2DM). Synonyms: ZP-10(Des-Pro38)-Exendin-4-(Lys)6, amide; ZP10A peptide; His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Ser-Lys-Lys-Lys-Lys-Lys-Lys-NH2; L-histidyl-glycyl-L-alpha-glutamyl-glycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-alpha-aspartyl-L-leucyl-L-seryl-L-lysyl-L-glutaminyl-L-methionyl-L-alpha-glutamyl-L-alpha-glutamyl-L-alpha-glutamyl-L-alanyl-L-valyl-L-arginyl-L-leucyl-L-phenylalanyl-L-isoleucyl-L-alpha-glutamyl-L-tryptophyl-L-leucyl-L-lysyl-L-asparagyl-glycyl-glycyl-L-prolyl-L-seryl-L-seryl-glycyl-L-alanyl-L-prolyl-L-prolyl-L-seryl-L-lysyl-L-lysyl-L-lysyl-L-lysyl-L-lysyl-L-lysinamide; AQVE-10010; Des-38-proline-exendine-4 (Heloderma suspectum)-(1-39)-peptidylpenta-L-lysyl-L-lysinamide. Grade: ≥95%. CAS No. 320367-13-3. Molecular formula: C215H347N61O65S. Mole weight: 4858.48.
LL-37 amide
LL-37 amide, an antimicrobial peptide, has angiogenic activity. Synonyms: Antibacterial Protein LL-37 amide (human); H-Leu-Leu-Gly-Asp-Phe-Phe-Arg-Lys-Ser-Lys-Glu-Lys-Ile-Gly-Lys-Glu-Phe-Lys-Arg-Ile-Val-Gln-Arg-Ile-Lys-Asp-Phe-Leu-Arg-Asn-Leu-Val-Pro-Arg-Thr-Glu-Ser-NH2; L-leucyl-L-leucyl-glycyl-L-alpha-aspartyl-L-phenylalanyl-L-phenylalanyl-L-arginyl-L-lysyl-L-seryl-L-lysyl-L-alpha-glutamyl-L-lysyl-L-isoleucyl-glycyl-L-lysyl-L-alpha-glutamyl-L-phenylalanyl-L-lysyl-L-arginyl-L-isoleucyl-L-valyl-L-glutaminyl-L-arginyl-L-isoleucyl-L-lysyl-L-alpha-aspartyl-L-phenylalanyl-L-leucyl-L-arginyl-L-asparagyl-L-leucyl-L-valyl-L-prolyl-L-arginyl-L-threonyl-L-alpha-glutamyl-L-serinamide. Grade: ≥95% by HPLC. CAS No. 597562-32-8. Molecular formula: C205H341N61O52. Mole weight: 4492.29.
LL-37, Human
LL-37 is a cationic and α-helical antimicrobial peptide. It can inhibit growth of Gram-positive E. coli D21 and Gram-negative B. megatarium in a concentration-dependent manner. LL-37 can promote wound healing following skin-targeted electroporation of a plasmid encoding hCAP-18/LL-37 in mice. Synonyms: LL 37; LL37; L-leucyl-L-leucyl-glycyl-L-alpha-aspartyl-L-phenylalanyl-L-phenylalanyl-L-arginyl-L-lysyl-L-seryl-L-lysyl-L-alpha-glutamyl-L-lysyl-L-isoleucyl-glycyl-L-lysyl-L-alpha-glutamyl-L-phenylalanyl-L-lysyl-L-arginyl-L-isoleucyl-L-valyl-L-glutaminyl-L-arginyl-L-isoleucyl-L-lysyl-L-alpha-aspartyl-L-phenylalanyl-L-leucyl-L-arginyl-L-asparagyl-L-leucyl-L-valyl-L-prolyl-L-arginyl-L-threonyl-L-alpha-glutamyl-L-serine; H-Leu-Leu-Gly-Asp-Phe-Phe-Arg-Lys-Ser-Lys-Glu-Lys-Ile-Gly-Lys-Glu-Phe-Lys-Arg-Ile-Val-Gln-Arg-Ile-Lys-Asp-Phe-Leu-Arg-Asn-Leu-Val-Pro-Arg-Thr-Glu-Ser-OH; Cathelicidin; Bac4; Cap-18. Grade: 98%. CAS No. 154947-66-7. Molecular formula: C205H340N60O53. Mole weight: 4493.25.
A cis-enol resorcylic acid lactone exhibiting antiviral and antiprotozoan activity. Synonyms: Zeaenol. Grade: >99% by HPLC. CAS No. 66018-41-5. Molecular formula: C19H24O7. Mole weight: 364.39.
L-NAME HCl
L-NAME is a nonselective inhibitor of nitric oxide synthetases (NOS) for nNOS (bovine), eNOS (human), and iNOS (murine), with Ki of 15 nM, 39 nM and 4.4 μM, respectively. Synonyms: Nω-Nitro-L-arginine methyl ester hydrochloride. Grade: 98%. CAS No. 51298-62-5. Molecular formula: C7H15N5O4.HCl. Mole weight: 269.69.
L-Norleucine
L-Norleucine, an isomer of leucine, specifically affects skeletal muscle protein synthesis and has antiviral activity. Uses: A non-essential amino acid. used as internal standard in amino acid analysis. Synonyms: Norleucine, L-; (S)-2-Aminohexanoic acid; (S)-Norleucine; (S)-α-Aminohexanoic acid; 2-Aminocaproic acid; L-(+)-Norleucine; L-2-Aminohexanoic acid; Caprine; Glycoleucine; Hexanoic acid, 2-amino-, (S)-; Norleucine; NSC 10378; NSC 74430; α-Aminocaproic acid. Grade: ≥97%. CAS No. 327-57-1. Molecular formula: C6H13NO2. Mole weight: 131.18.
Lomefloxacin hydrochloride is a fluoroquinolone antibiotic used to treat bacterial infections including bronchitis and urinary tract infections. Synonyms: Lomefloxacin hydrochloride; Maxaquin; Ny-198; Bareon; SC 4711; SC-4711; SC4711. Grade: >98%. CAS No. 98079-52-8. Molecular formula: C17H20ClF2N3O3. Mole weight: 387.81.
Lomofungin
It is produced by the strain of Str. lomondensis var. lomondensis NRRL 3252. It is an antibiotic of the phenazine derivatives. It has anti-bacterial and fungal effects, but the anti-bacterial effects are weak. Synonyms: Lomondomycin; NSC 106995; NSC 156939; U-24792; 1-carbomethoxy-5-formyl-4,6,8-trihydroxyphenazine; 6-Formyl-4,7,9-trihydroxy-1-phenazinecarboxylic acid methyl ester. Grade: >95%. CAS No. 26786-84-5. Molecular formula: C15H10N2O6. Mole weight: 314.25.
Loratadine EP Impurity A
Loratadine EP Impurity A is an impurity of Loratadine, which is a histamine H1 receptor antagonist used to treat allergies. Synonyms: ethyl 4-[(11RS)-8-chloro-11-hydroxy-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl]piperidine-1-carboxylate; 11-Hydroxy Dihydro Loratadine; 4-(8-Chloro-6,11-dihydro-11-hydroxy-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-1-piperidinecarboxylic Acid Ethyl Ester; Loratadine USP Related Compound F; 1-Piperidinecarboxylic acid, 4-(8-chloro-6,11-dihydro-11-hydroxy-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-, ethyl ester; Ethyl 4-(8-chloro-6,11-dihydro-11-hydroxy-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-1-piperidinecarboxylate; 11-Hydroxyloratadine; Ethyl 4-(8-chloro-11-hydroxy-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)piperidin-1-carboxylate; Hydroxyloratadine. Grade: ≥95%. CAS No. 133284-74-9. Molecular formula: C22H25ClN2O3. Mole weight: 400.90.
Loratadine EP Impurity E
Loratadine EP Impurity E is an impurity of Loratadine, which is a histamine H1 receptor antagonist used to treat allergies. Synonyms: Ethyl 4-[(11RS)-8-chloro-6,11-dihydro-5H-benzo-[5,6]cyclohepta[1,2-b]pyridin-11-yl]-3,6-dihydropyridine-1(2H)-carboxylate; 1(2H)-Pyridinecarboxylic acid, 4-(8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-3,6-dihydro-, ethyl ester; Isoloratadine; Iso Loratadine; 4-(8-Chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-3,6-dihydro-1(2H)-pyridinecarboxylic Acid Ethyl Ester. Grade: ≥95%. CAS No. 170727-59-0. Molecular formula: C22H23ClN2O2. Mole weight: 382.88.
LPA Biotin
LPA Biotin is labelled at the sn-1 position. LPA is a small lysophospholipid involved in diverse cellular processes such as cell proliferation, chemotaxis, platelet aggregation, wound healing, angiogenesis, tumor invasion, and smooth muscle contraction. Synonyms: Lysophosphatidic Acid Biotin. Molecular formula: C31H56N4NaO10PS. Mole weight: 730.83.
L-Phenylalanyl-L-tryptophan
L-Phenylalanyl-L-tryptophan, also known as Dipeptide-4, is a dipeptide consisting of L-phenylalanine and L-tryptophan. It has been shown to effectively prevent skin cell glycation, which helps protect the skin from environmental stress and prevents the skin from deteriorating prematurely. This peptide is used in cosmetic formulations to maintain skin health and prevent the signs of aging due to its role in combating glycation, a process that can lead to skin elasticity loss and the formation of wrinkles. It is a highly potent ACE inhibitor. Synonyms: Dipeptide-4; Phenylalanyltryptophan; Phe-Trp; FW dipeptide; Phenylalanine Tryptophan dipeptide; H-Phe-Trp-OH; Nα-(L-Phenylalanyl)-L-tryptophan; Phe-Trp-OH; FW dipeptide; F-W Dipeptide; L-Tryptophan, N-L-phenylalanyl-; (S)-2-((S)-2-Amino-3-phenylPropanamido)-3-(1H-indol-3-yl)Propanoic acid; L-Phe-L-Trp; N-Phenylalanyltryptophan; N-L-phenylalanyl-L-tryptophan. Grade: ≥95%. CAS No. 24587-41-5. Molecular formula: C20H21N3O3. Mole weight: 351.40.
L-Prolyl-L-leucylglycinamide, an inhibitor of melanocyte-stimulating hormone (MSH) release, is shown to be effective in treating human depression with greater efficacy and faster onset of action than traditional anti-depressants. It blocks the release of α-MSH, and increases brain dopamine levels and antagonizes physiological and behavioral opioid effects in vivo. Uses: Hormones. Synonyms: Pro-Leu-Gly-NH2; Melanocyte Inhibiting Factor; MSH Release Inhibiting Hormone. CAS No. 2002-44-0. Molecular formula: C13H24N4O3. Mole weight: 284.36.
L-Prolyl-L-phenylalanine
L-Prolyl-L-phenylalanine is an ACE2 inhibitor with an IC50 of 0.15 μM. Synonyms: Pro-Phe; L-Pro-L-Phe; prolylphenylalanine; (S)-3-Phenyl-2-((S)-pyrrolidine-2-carboxamido)Propanoic acid. CAS No. 13589-02-1. Molecular formula: C14H18N2O3. Mole weight: 262.30.
LPS-EB Biotin
LPS-EB Biotin is a biotinylated ultrapure smooth lipopolysaccharide (sLPS) from the Gram-negative bacteria E. coli 0111:B4. Synonyms: Biotinylated LPS from Escherichia coli 0111:B4.
LPYFD-NH2
LPYFD-NH2, is a neuroprotective peptide that binds to Amyloid-β. In vitro and in vivo it protects neurons against toxic effects of Aβ (1-42), which can be used in treating Alzheimer's Disease. Synonyms: H-Leu-Pro-Tyr-Phe-Asp-NH2; (3S)-4-amino-3-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-amino-4-methylpentanoyl]pyrrolidine-2-carbonyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-phenylpropanoyl]amino]-4-oxobutanoic acid; ZINC98052568; AKOS024457970. CAS No. 700361-48-4. Molecular formula: C33H44N6O8. Mole weight: 652.75.
L-Pyroglutamic acid
L-Pyroglutamic acid is a cyclized derivative of L-glutamic acid. Protein supplement in health care products. Uses: Ingredient of health care products. Synonyms: Pyroglutamic acid; Pidolic acid; H-Pyr-OH; 5-oxo-L-proline; (2S)-5-oxopyrrolidine-2-carboxylic acid. Grade: 95%. CAS No. 98-79-3. Molecular formula: C5H7NO3. Mole weight: 129.11.
L-Pyrrolidonecarboxyl-L-Alanine
Intermediate for peptides. Synonyms: Pyr-Ala-OH; 5-oxo-L-prolyl-L-alanine. Grade: ≥ 99% (HPLC). CAS No. 21282-08-6. Molecular formula: C8H12N2O4. Mole weight: 200.2.
L-R
L-R is a vanilloid TRPV1 (VR1) receptor antagonist peptide (IC50 ~ 0.1 μM). Synonyms: L-R4W2. Grade: >98%. CAS No. 206350-79-0. Molecular formula: C46H71N21O6. Mole weight: 1014.2.
LRGILS-NH
LRGILS-NH is a control peptide for SLIGRL-NH2, a protease-activated receptor-2 (PAR2) agonist that facilitates gastrointestinal transit in vivo. Synonyms: L-leucyl-L-arginylglycyl-L-isoleucyl-L-leucyl-L-serinamide. Grade: ≥95% by HPLC. CAS No. 245329-01-5. Molecular formula: C29H56N10O7. Mole weight: 656.83.
L-Selenomethionine
L-Selenomethionine is the predominant food form of selenium with antioxidant activity. L-Selenomethionine has been shown to increase the activity of glutathione peroxidase in endothelial cells. It may be chemoprotective against certain cancers. Nutritional supplement in health care products. Uses: L-selenomethionine (semet) is a naturally occurring amino acid derivative that contains selenium instead of sulfur in the methionine residue. selenium is an essential trace element that plays a crucial role in various biochemical pathways in the body, acting as a cofactor for antioxidant enzymes and contributing to redox balance. the incorporation of semet into proteins during translation provides. Synonyms: Selenomethionine; L-(+)-Selenomethionine; Selenium-L-methionine; L-Selenomethioninum; Seleno-L-methionine; H-Mse-OH; (2S)-2-amino-4-methylselanylbutanoic acid. Grade: 95%. CAS No. 3211-76-5. Molecular formula: C5H11NO2Se. Mole weight: 196.12.
LSKL, Inhibitor of Thrombospondin TSP-1
LSKL, Inhibitor of Thrombospondin (TSP-1), derived from the latency-associated peptide, inhibits thrombospondin (TSP-1) activation of TGF-β, thus prevents the progression of hepatic damage and fibrosis. Synonyms: H-LSKL-NH2; L-leucyl-L-seryl-L-lysyl-L-leucinamide. Grade: ≥98%. CAS No. 283609-79-0. Molecular formula: C21H42N6O5. Mole weight: 458.59.
LSTc-biotin
LSTc-biotin: An innovative tool for probing LSTc glycan structures that lurk on the surfaces of certain cancer cells and immune cells. With its unparalleled specificity for LSTc, this form of biotin serves as a pivotal reagent in the biomedical investigation of cancer and inflammatory diseases. Via fluorescence labeling of the target cells, LSTc-biotin endows researchers with extraordinary insight into the behavior of these cells and propels the development of novel therapies for ailments such as rheumatoid arthritis and cancer. Synonyms: O-(N-Acetyl-α-neuraminosyl)-(2→6)-O-β-D-galactopyranosyl-(1→4)-O-2-(acetylamino)-2-deoxy-β-D-glucopyranosyl-(1→3)-O-β-D-galactopyranosyl-(1→4)-D-glucose-biotin; LS-tetrasaccharide c-biotin; Sialyllacto-N-neotetraose c-biotin; SLNT-c-biotin. Molecular formula: C53H89N7O31S. Mole weight: 1352.37.
LS-tetrasaccharide C-sp-biotin
LS-tetrasaccharide C-sp-biotin.
L-threo-β-Hydroxyaspartic acid
L-threo-β-Hydroxyaspartic acid is an amino acid antibiotic produced by Arthrinium phaeospermum T-53 and Streptomyces sp. 7540-MC1. It has the activity of inhibiting Bacillus subtilis, Xanthomonas oryzae, Mycobacterium phlei and Botrytis cinerea. Synonyms: (3R)-3-hydroxy-L-aspartic acid; Erythro-beta-hydroxy-L-aspartic acid; erythro-beta-Hydroxyaspartic acid; (3R)-3-Hydroxyaspartate. Grade: 95%. CAS No. 7298-98-8. Molecular formula: C4H7NO5. Mole weight: 149.10.
L-Threoninol(Ac)-8-Octreotide
L-Threoninol(Ac)-8-Octreotide is an impurity of Octreotide, which is a synthetic long-acting cyclic octapeptide used as a more potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Synonyms: DPhe-Cys-Phe-DTrp-Lys-Thr-Cys-Thr-ol-Ac(Cys2&Cys7 bridge); DPhe-CF-DTrp-KTC-Thr-ol-Ac(Cys2&Cys7 bridge); O1.8-Acetyloctreotide; Octreotide EP Impurity F; D-Phenylalanyl-L-cystyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-L-cystyl-L(Acetyl)-threoninol (Disulfide Bridge between Cys2-Cys7); Octreotide Impurity F; H-D-Phe-Cys-Phe-D-Trp-Lys-Thr-Cys-Ac-Thr-ol (Disulfide bridge: Cys2-Cys7); L-Cysteinamide, D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[1-[(acetyloxy)methyl]-2-hydroxypropyl]-, cyclic (2→7)-disulfide, [R-(R*,R*)]-; O-Acetyl Octreotide; [O1(AC)]8-Octreotide; (L-Threoninol(Ac)8)-Octreotide. Grade: ≥95%. CAS No. 133304-81-1. Molecular formula: C51H68N10O11S2. Mole weight: 1061.28.
LTX-315
LTX-315, an oncolytic peptide with potent anticancer activity, kills cancer cells through Bax/Bak-regulated mitochondrial membrane permeabilization. LTX-315 inhibits MRC-5, A20 and AT84 with IC50s of 34.3, 8.3 and 11 μM, respectively. Synonyms: LTX 315; LTX315; Ruxotemitide; H-Lys-Lys-Trp-Trp-Lys-Lys-Trp-Dip-Lys-NH2; L-lysyl-L-lysyl-L-tryptophyl-L-tryptophyl-L-lysyl-L-lysyl-L-tryptophyl-3,3-diphenyl-L-alanyl-L-lysinamide; Oncopore; (S)-2,6-diamino-N-((5S,8S,11S,14S,17S,20S,23S,26S)-11,20,23-tris((1H-indol-3-yl)methyl)-1,30-diamino-14,17-bis(4-aminobutyl)-8-benzhydryl-5-carbamoyl-7,10,13,16,19,22,25-heptaoxo-6,9,12,15,18,21,24-heptaazatriacontan-26-yl)hexanamide. Grade: ≥95%. CAS No. 1345407-05-7. Molecular formula: C78H106N18O9. Mole weight: 1439.79.
L-Tyrosine-[15N]
L-Tyrosine-[15N] is a labelled L-Tyrosine. Tyrosine is a non-essential amino acid synthesized from phenylalanine. It is the precursor of some neurotransmitters. Synonyms: (S)-2-Amino-3-(4-hydroxyphenyl)propionic acid-15N; 3-(4-Hydroxyphenyl)-L-alanine-15N; L-4-Hydroxyphenylalanine-15N; 15N Labeled L-tyrosine. Grade: 98% by HPLC; 98% atom 15N. CAS No. 35424-81-8. Molecular formula: C9H11[15N]O3. Mole weight: 182.18.
L-Tyrosine,L-tyrosyl-L-tyrosyl-
Tyr-Tyr and Tyr-Tyr-Tyr efficiently inhibit angiotensin I-converting enzyme (ACE) from rabbit lung, their IC50 values were 34 μM and 51 μM, respectively. These two tyrosine peptides exhibited a mix of competitive and noncompetitive inhibitions. Synonyms: Tyrosyl-tyrosyl-tyrosine; L-Tyr-L-Tyr-L-Tyr-OH; L-Tyrosyl-L-tyrosyl-L-tyrosine; (S)-2-((S)-2-((S)-2-Amino-3-(4-hydroxyphenyl)propanamido)-3-(4-hydroxyphenyl)propanamido)-3-(4-hydroxyphenyl)propanoic acid. CAS No. 7390-78-5. Molecular formula: C27H29N3O7. Mole weight: 507.54.
Luzopeptin A
Luzopeptin A is a cyclic depsipeptide antibiotic produced by an actinomycete strain. It has anti-tumor activity. It is a potent inhibitor of HIV-1 reverse transcriptase. Synonyms: Luzopeptin A; 75580-37-9; Bbm-928 A; BBM-928A; Diacetyl-luzopeptin C; [(3R,7S,16S,17S,23R,27S,36S,37S)-37-acetyloxy-3,23-bis[(3-hydroxy-6-methoxyquinoline-2-carbonyl)amino]-7,27-bis(2-hydroxypropan-2-yl)-8,11,28,31-tetramethyl-2,6,9,12,15,22,26,29,32,35-decaoxo-5,25-dioxa-1,8,11,14,20,21,28,31,34,40-decazatricyclo[34.4.0.016,21]tetraconta-19,39-dien-17-yl] acetate; Luzopeptin C, 2,7-diacetate; Antibiotic BBM 928C, 2,7-diacetate; [37-Acetyloxy-3,23-bis[(3-hydroxy-6-methoxyquinoline-2-carbonyl)amino]-7,27-bis(2-hydroxypropan-2-yl)-8,11,28,31-tetramethyl-2,6,9,12,15,22,26,29,32,35-decaoxo-5,25-dioxa-1,8,11,14,20,21,28,31,34,40-decazatricyclo[34.4.0.016,21]tetraconta-19,39-dien-17-yl] acetate; Antibiotic BBM 928A; BRN 5725577; BBM 928A; SCHEMBL20614463; CHEBI:223532; DTXSID401317872; NSC308312; HY-130050; CS-0104626. Grade: >99% by HPLC. CAS No. 75580-37-9. Molecular formula: C24H32O6. Mole weight: 416.5.
L-Valine methyl ester hydrochloride
An impurity of Valsartan. Valsartan is an antagonist of angiotensin II receptor mainly used for the treatment of high blood pressure and congestive heart failure. Synonyms: L-Val-OMe HCl; L-Valine, methyl ester, hydrochloride (1:1); L-Valine, methyl ester, monohydrochloride; Valine, methyl ester, hydrochloride, L-; (S)-Valine methyl ester hydrochloride; Methyl (S)-2-amino-3-methylbutanoate hydrochloride; Methyl (S)-valinate hydrochloride; Methyl L-valinate hydrochloride; Methyl L-valine hydrochloride; Methyl valinate hydrochloride; NSC 197198; NSC 22920; Valine methyl ester hydrochloride. Grade: ≥95%. CAS No. 6306-52-1. Molecular formula: C6H13NO2.HCl. Mole weight: 167.63.
LY-2510924
LY-2510924 is an inhibitor of CXC chemokine receptor 4 (CXCR4). It has potential antineoplastic activity. It binds to the chemokine receptor CXCR4, thereby preventing CXCR4 binding to its ligand, stromal derived factor-1 (SDF-1), and subsequent receptor activation upon subcutaneous administration, which may result in decreased tumor cell proliferation and migration. It plays an important role in chemotaxis and angiogenesis and is upregulated in several tumor cell types. Uses: Ly-2510924 has potential antineoplastic activity. it plays an important role in chemotaxis and angiogenesis. Synonyms: LY2510924; LY 2510924; Cyclo[Phe-Tyr-Lys(iPr)-D-Arg-2-Nal-Gly-D-Glu]-Lys(iPr)-NH2; Cyclo[Phe-Tyr-Lys(iPr)-D-Arg-2-Nal-Gly-D-Glu]-Lys(iPr)-NH2; L-Lysinamide, L-phenylalanyl-L-tyrosyl-N6-(1-methylethyl)-L-lysyl-D-arginyl-3-(2-naphthalenyl)-L-alanylglycyl-D-α-glutamyl-N6-(1-methylethyl)-, (7→1)-lactam; N(1)Phe-Tyr-Lys(iPr)-D-Arg-2Nal-Gly-D-Glu(1)-Lys(iPr)-NH2. Grade: 98%. CAS No. 1088715-84-7. Molecular formula: C62H88N14O10. Mole weight: 1189.47.
LY2510924 acetate
Ly2510924 acetate is a potent and selective CXCR4 antagonist that prevents the binding of SDF-1 to CXCR4 with an IC50 of 0.079 nM. It has potential antineoplastic activity. Synonyms: L-Lysinamide, L-phenylalanyl-L-tyrosyl-N6-(1-methylethyl)-L-lysyl-D-arginyl-3-(2-naphthalenyl)-L-alanylglycyl-D-α-glutamyl-N6-(1-methylethyl)-, (7→1)-lactam, acetate (1:1); LY 2510924 acetate; LY-2510924 acetate; N(1)Phe-Tyr-Lys(iPr)-D-Arg-2Nal-Gly-D-Glu(1)-Lys(iPr)-NH2 acetate. Grade: ≥95%. Molecular formula: C62H88N14O10.C2H4O2. Mole weight: 1249.53.
Lydicamycin
It is produced by the strain of Str. lydicus. It has anti-gram-positive bacterial effect, as well as methicillin-resistant (MRSA) staphylococcus aureus. Synonyms: Indicine N-oxide; lycopsamine A N-oxide; INDI; Echinatine, N-oxide. Grade: >95% by HPLC. CAS No. 133352-27-9. Molecular formula: C47H74N4O10. Mole weight: 855.12.
Lyn peptide inhibitor
A potent and cell-permeable inhibitor of Lyn-coupled IL-5 receptor signaling pathway. Synonyms: stearoyl-DL-Tyr-Gly-DL-Tyr-DL-Arg-DL-Leu-DL-Arg-DL-Arg-DL-Lys-DL-Trp-DL-Glu-DL-Glu-DL-Lys-DL-xiIle-DL-Pro-DL-Asn-DL-Pro-NH2. Grade: >98%. CAS No. 222018-18-0. Molecular formula: C115H184N30O24. Mole weight: 2370.91.
Lyn peptide inhibitor acetate
Lyn peptide inhibitor acetate is a potent and cell-permeable inhibitor of the Lyn-coupled IL-5 receptor signaling pathway, while keeping other signals intact. It blocks Lyn activation and inhibits the binding of Lyn tyrosine kinase to the βc subunit of IL-3/GM-CSF/IL-5 receptors. It can be used for the study of asthma, allergic, and other eosinophilic disorders. Synonyms: stearoyl-Tyr-Gly-Tyr-Arg-Leu-Arg-Arg-Lys-Trp-Glu-Glu-Lys-Ile-Pro-Asn-Pro-NH2.CH3CO2H; N-stearoyl-L-tyrosyl-glycyl-L-tyrosyl-L-arginyl-L-leucyl-L-arginyl-L-arginyl-L-lysyl-L-tryptophyl-L-alpha-glutamyl-L-alpha-glutamyl-L-lysyl-L-isoleucyl-L-prolyl-L-asparagyl-L-prolinamide acetic acid; N-(1-Oxooctadecyl)-L-tyrosylglycyl-L-tyrosyl-L-arginyl-L-leucyl-L-arginyl-L-arginyl-L-lysyl-L-tryptophyl-L-α-glutamyl-L-α-glutamyl-L-lysyl-L-isoleucyl-L-prolyl-L-asparaginyl-L-prolinamide acetate. Grade: ≥95%. CAS No. 2918771-52-3. Molecular formula: C117H188N30O26. Mole weight: 2430.98.
(Lys22)-Amyloid β-Protein (1-40)
(Lys22)-Amyloid β-Protein (1-40) is an Italian mutation of β-amyloid 1-40 (E22K), which aggregates faster than wild-type sequence 1-40. It exhibits higher neurotoxicity, probably due to the salt bridge formed between Lys22 and Asp23 in the minor conformer. Like the Arctic, Flemish and Dutch mutants, it is degraded by neprilysin much more slowly than the wild-type Aβ. Synonyms: Amyloid β-Protein (1-40) Italian Mutation; H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Lys-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-OH; L-Valine, L-α-aspartyl-L-alanyl-L-α-glutamyl-L-phenylalanyl-L-arginyl-L-histidyl-L-α-aspartyl-L-serylglycyl-L-tyrosyl-L-α-glutamyl-L-valyl-L-histidyl-L-histidyl-L-glutaminyl-L-lysyl-L-leucyl-L-valyl-L-phenylalanyl-L-phenylalanyl-L-alanyl-L-lysyl-L-α-aspartyl-L-valylglycyl-L-seryl-L-asparaginyl-L-lysylglycyl-L-alanyl-L-isoleucyl-L-isoleucylglycyl-L-leucyl-L-methionyl-L-valylglycylglycyl-L-valyl-. Grade: ≥95%. CAS No. 302905-01-7. Molecular formula: C195H300N54O56S. Mole weight: 4328.92.