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Lys(Ac)-Octreotide
Lys(Ac)-Octreotide is an impurity of Octreotide, which is a synthetic long-acting cyclic octapeptide used as a more potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Uses: Radiopharmaceuticals. Synonyms: DPhe-Cys-Phe-DTrp-Lys(Ac)-Thr-Cys-Thr-ol(Cys2&Cys7 bridge); N6.5-Acetyloctreotide; D-Phe-c(Cys-Phe-D-Trp-Lys(Ac)-Thr-Cys)-Thr-ol; Lys(Ac) 5 Octreotide; D-Phenylalanyl-L-cystyl-L-phenylalanyl-D-tryptophyl-L-lysyl(acetyl)-L-threonyl-L-cystyl-L-threoninol (Disulfide Bridge between Cys2-Cys7); L-Cysteinamide, D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-N6-acetyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2→7)-disulfide; D-Phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-N6-acetyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-L-cysteinamide cyclic (2→7)-disulfide; L-Cysteinamide, D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-N6-acetyl-L-lysyl-L-threonyl-N-[2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2→7)-disulfide, [R-(R*,R*)]-; Octreotide EP Impurity H; Octreotide Impurity H; Acetyl-Lys5-octreotide; D-Phenylalanyl-L-hemicystyl-L-phenylalanyl-D-tryptophyl-(N-acetyl)-L-lysyl-L-threonyl-L-hemicystyl-L-threoninol cyclic (2→7)-disulfide. Grade: ≥95%. CAS No. 173606-11-6. Molecular formula: C51H68N10O11S2. Mole weight: 1061.28.
Lys-Bradykinin
Lys-Bradykinin is an endogenous bradykinin receptor agonist with selectivity for the B2 receptor (Ki = 2.54 and 0.63 nM at human B1 and B2 receptors, respectively). It is used as a hypotensive agent that reduces peripheral vascular resistance in vivo. Uses: Hypotensive agent. Synonyms: Kallidin. CAS No. 342-10-9. Molecular formula: C56H85N17O12. Mole weight: 1188.39.
Lys-Bradykinin acetate
Lys-Bradykinin acetate is an endogenous bradykinin receptor agonist with selectivity for the B2 receptor (Ki = 2.54 and 0.63 nM at human B1 and B2 receptors, respectively). It is used as a hypotensive agent that reduces peripheral vascular resistance in vivo. Synonyms: H-Lys-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-OH.CH3CO2H; L-lysyl-L-arginyl-L-prolyl-L-prolyl-glycyl-L-phenylalanyl-L-seryl-L-prolyl-L-phenylalanyl-L-arginine acetic acid. Grade: ≥95%. Molecular formula: C58H89N17O14. Mole weight: 1248.43.
Lys-[Des-Arg9]Bradykinin
Lys-[Des-Arg9]Bradykinin is a potent and highly selective bradykinin B1 receptor agonist (Ki value 0.12 and > 30000 nM at human B1 and B2 receptors, respectively) with 16-fold potency against [Des-Arg9]-Bradykinin. It is used as a hypotensive agent and reduces peripheral vascular resistance in vivo. Uses: Hypotensive agent. Synonyms: des-Arg10-Kallidin; [Lys-des-Arg9]-Bradykinin. CAS No. 71800-36-7. Molecular formula: C50H73N13O11. Mole weight: 1032.21.
Lys-[Des-Arg9]Bradykinin acetate
Lys-[Des-Arg9]Bradykinin acetate is a potent and highly selective bradykinin B1 receptor agonist (Kis are 0.12 and >30000 nM at human B1 and B2 receptors, respectively) with 16-fold potency against [Des-Arg9]-Bradykinin. It is used as a hypotensive agent and reduces peripheral vascular resistance in vivo. Synonyms: H-Lys-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-OH.CH3CO2H; L-lysyl-L-arginyl-L-prolyl-L-prolyl-glycyl-L-phenylalanyl-L-seryl-L-prolyl-L-phenylalanine acetic acid; 1-9-Kallidin acetate; N2-L-Lysyl-9-de-L-arginine-Bradykinin acetate. Grade: ≥95%. CAS No. 2760881-54-5. Molecular formula: C52H77N13O13. Mole weight: 1092.27.
Lys-(Des-Arg9,Leu8)-Bradykinin
Lys-(Des-Arg9,Leu8)-Bradykinin is an antagonist of B1 bradykinin receptor. Synonyms: (Des-Arg10,Leu9)-Kallidin; H-Lys-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Leu-OH; L-lysyl-L-arginyl-L-prolyl-L-prolyl-glycyl-L-phenylalanyl-L-seryl-L-prolyl-L-leucine; L-Lysyl-N5-(diaminomethylene)-L-ornithyl-L-prolyl-L-prolylglycyl-L-phenylalanyl-L-seryl-L-prolyl-L-leucine. Grade: ≥95%. CAS No. 71800-37-8. Molecular formula: C47H75N13O11. Mole weight: 998.18.
Lysipressin
Lysipressin is a synthetic analogue of the natural hormone vasopressin, originally discovered in pigs. It functions as an antidiuretic hormone and possesses both vasoconstrictive and antidiuretic properties. Synonyms: Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Lys-Gly-NH2(Cys1&Cys6 bridge); Des-(1-3)-terlipressin; CYFQNCPKG-NH2(Cys1&Cys6 bridge); Terlipressin EP Impurity C; Terlipressin Impurity C; Des-Gly1-Gly2 Gly3 Terlipressin; H-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Lys-Gly-NH2 (Disulfide bridge: Cys1-Cys6); L-Cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-asparagyl-L-cysteinyl-L-prolyl-L-lysyl-glycinamide (1->6)-disulfide; Des-1,2,3-Triglycine-Terlipressin; 8-L-Lysinevasopressin; 3-(Phenylalanine)-8-lysine oxytocin; 8-L-Lysine vasopressin; L-Lysine vasopressin; [8-Lysine]vasopressin; Diapid; Glycinamide, L-cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-asparaginyl-L-cysteinyl-L-prolyl-L-lysyl-, cyclic (1→6)-disulfide; L 8; Lypressin; Lysine pitressin; Lysine vasopressin; Lysine-ADH; Lysopressin; Lysylvasopressin; 3-(L-Phenylalanine)-8-L-lysine-oxytocin; Postacton; Syntopressin; Vasophysin; Vasopressin-8-lysine. Grade: 98%. CAS No. 50-57-7. Molecular formula: C46H65N13O12S2. Mole weight: 1056.22.
Lysipressin Acetate
Lysipressin Acetate is a lysine vasopressin, which retains water in the body and constricts blood vessels. Synonyms: Vasopressin, 8-L-lysine-, monoacetate (salt); Des-(1-3)-terlipressin acetate salt; Terlipressin EP Impurity C acetate salt; Des-Gly1-Gly2 Gly3 Terlipressin acetate salt; H-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Lys-Gly-NH2.C2H4O2 (Disulfide bridge: Cys1-Cys6); L-Cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-asparagyl-L-cysteinyl-L-prolyl-L-lysyl-glycinamide (1->6)-disulfide acetate salt; Des-1,2,3-Triglycine-Terlipressin acetate salt; 8-L-Lysine vasopressin acetate salt; L-Lysine vasopressin acetate salt; Vasopressin-8-lysine acetate salt. Grade: ≥95%. CAS No. 83968-49-4. Molecular formula: C48H69N13O14S2. Mole weight: 1116.27.
[Lys(Me3)36]-Histone H3 (21-44)-Gly-Lys(biotinyl) is a derivative of Histone H3, a fundamental unit of chromatin. Synonyms: [Lys(Me3)36]-Histone H3 (21-44)-GK(Biotin); H3K36(Me3), biotin-labeled; Ala-Thr-Lys-Ala-Ala-Arg-Lys-Ser-Ala-Pro-Ala-Thr-Gly-Gly-Val-Lys(Me3)-Lys-Pro-His-Arg-Tyr-Arg-Pro-Gly-Gly-Lys(Biotin). Molecular formula: C130H220N44O33S. Mole weight: 2959.5.
Lysobactin, also known as katanosin B, is a potent antibiotic with in vivo efficacy against Staphylococcus aureus and Streptococcus pneumoniae. It was previously shown to inhibit peptidoglycan (PG) biosynthesis. Synonyms: Katanosin B; Katanosin A, 7-L-isoleucine-. Grade: >98%. CAS No. 118374-47-3. Molecular formula: C58H97N15O17. Mole weight: 1276.48.
Lysozyme from chicken egg white
It's a bactericidal enzyme found in eggs that lyses gram-positive bacteria. Uses: Lysozyme is a naturally occurring enzyme found in large quantities in chicken egg white that has shown great potential in the field of drug development. this versatile enzyme has attracted much attention for its antimicrobial properties and its ability to catalyze the hydrolysis of peptidoglycan, a key component of the bacterial cell wall. antimicrobial properties: strong antibacterial activity i. Synonyms: Lysozymum; Lysozyme; Lysozyme, Egg White; AT25331; DA-75223; H-DL-Arg-DL-Val-DL-Val-DL-Arg-DL-Asp-DL-Pro-DL-Gln-Gly-DL-xiIle-DL-Arg-DL-Ala-DL-Trp-DL-Val-DL-Ala-DL-Trp-DL-Arg-DL-Asn-DL-Arg-OH. CAS No. 12650-88-3.
Lysozymum
Lysozyme is an antimicrobial enzyme produced by animals, damaging bacterial cell walls via hydrolysis between residues in peptidoglycan walls. Synonyms: Mucopeptide N-acetylmuramoylhydrolase, Muramidase; 1,4-N-Acetylmuramidase; 1,4-β-N-Acetylmuramidase; 100940; Delvozyme; Delvozyme L; E.C. 3.2.1.17; Globulin G; Globulin G1; KLP 602; LumiVida; Lydium-KLP; Mucopeptide glucohydrolase; Muramidase; N,O-Diacetylmuramidase; Peptidoglycan N-acetylmuramoylhydrolase; Thermodase; β-1,4-N,6-O-Diacetylmuramidase; β-1,4-N-Acetylmuramidase. Grade: >98%. CAS No. 9001-63-2. Molecular formula: C99H159N37O23. Mole weight: 2235.6.
m32.2.7GP3G (Trimethylated Cap Analog) is an indispensable compound of paramount significance, meticulously employed for the purpose of synthesizing mRNA molecules. By judiciously interweaving this cap analog within the process of mRNA transcription, it bestows a marked amplification in translational efficiency, stability and the intricate realm of translation initiation. Synonyms: G(5')ppp(5')G; P; -(5'-2,2,7-trimethyl-guanosyl) P; -(5'-(guanosyl))triphosphate, Sodium salt. Grade: ≥ 95 % by HPLC. CAS No. 123212-20-4. Molecular formula: C23H33N10O18P3(free acid). Mole weight: 830.49 (free acid).
M40
M40 is a potent, non-selective antagonist of galanin receptor, and has no effect on chow or fat intake. Synonyms: M 40; M-40; H-Gly-Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-Gly-Pro-Pro-Pro-Ala-Leu-Ala-Leu-Ala-NH2; L-Alaninamide, glycyl-L-tryptophyl-L-threonyl-L-leucyl-L-asparaginyl-L-seryl-L-alanylglycyl-L-tyrosyl-L-leucyl-L-leucylglycyl-L-prolyl-L-prolyl-L-prolyl-L-alanyl-L-leucyl-L-alanyl-L-leucyl-; Glycyl-L-tryptophyl-L-threonyl-L-leucyl-L-asparaginyl-L-seryl-L-alanylglycyl-L-tyrosyl-L-leucyl-L-leucylglycyl-L-prolyl-L-prolyl-L-prolyl-L-alanyl-L-leucyl-L-alanyl-L-leucyl-L-alaninamide; M 40 (peptide). Grade: ≥95%. CAS No. 143896-17-7. Molecular formula: C95H146N22O24. Mole weight: 1980.31.
M40 acetate
M40 acetate is a potent, non-selective antagonist of galanin receptor, and has no effect on chow or fat intake. Synonyms: H-Gly-Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-Gly-Pro-Pro-Pro-Ala-Leu-Ala-Leu-Ala-NH2.CH3CO2H; glycyl-L-tryptophyl-L-threonyl-L-leucyl-L-asparagyl-L-seryl-L-alanyl-glycyl-L-tyrosyl-L-leucyl-L-leucyl-glycyl-L-prolyl-L-prolyl-L-prolyl-L-alanyl-L-leucyl-L-alanyl-L-leucyl-L-alaninamide acetic acid; M 40 acetate. Grade: ≥95%. Molecular formula: C96H149N23O26. Mole weight: 2041.38.
m7G(N-biotin)pppG
m7G(N-biotin)pppG is an amino- and carboxy-functionalized dinucleotide 5' cap analog that is suitable for labeling with biotin or fluorescent tags by the employment of an in situ NHS activation strategy. Synonyms: P1-(2'-aminobiotinyl-2'-deoxy-N7-methylguanosin-5'-yl) P3-(guanosin-5'-yl) triphosphate. Molecular formula: C31H41N13O19P3S3 (free base). Mole weight: 1024.72 (free base).
m7GP3G (Monomethylated Cap Analog)
m7GP3G (Monomethylated Cap Analog) is an indispensable compound extensively employed, supporting the synthesis of mRNAs possessing altered RNA cap structures. This remarkable compound assumes a pivotal function in advancing studies pertaining to gene expression and mRNA processing, particularly in the progressive frontiers of RNA vaccines and mRNA therapeutics. By enabling investigation into cap-dependent translation mechanisms, as well as facilitating the evaluation of mRNA stability and translational efficiency, this product fosters an unprecedented comprehension of intricate cellular processes. Synonyms: Guanosine 5'-(tetrahydrogen triphosphate), P''→5'-ester with 2-amino-6,9-dihydro-7-methyl-6-oxo-9-β-D-ribofuranosyl-1H-purinium inner salt; m7Gp3G; m7GpppG; mG(5')ppp(5')G; P1-(5'-7-methyl-guanosyl) P3-(5'-(guanosyl))triphosphate; mCAP; m7G(5')ppp(5')G Cap Analog; N7-Methyl-Guanosine-5'-Triphosphate-5'-Guanosine; 7-Methyl-guanosine-5'-triphosphate-5'-guanosine; M7-GpppG. Grade: ≥95% by HPLC. CAS No. 62828-64-2. Molecular formula: C21H29N10O18P3. Mole weight: 802.43.
m7GP3G (Monomethylated Cap Analog) sodium salt
m7GP3G (Monomethylated Cap Analog) sodium salt is a vital product in the biomedical industry used for studying mRNA capping and translation initiation. It serves as a crucial tool for investigating RNA transcription, translation processes and mRNA stability. By mimicking the natural RNA cap structure, m7GP3G sodium salt aids in understanding diseases like cancer and viral infections, ultimately enabling the development of effective researchs. Synonyms: m7G(5')ppp(5')G Sodium salt; P1-(5'-7-methyl-guanosyl) P3-(5'-(guanosyl))triphosphate, sodium salt; M7-GpppG sodium salt; Guanosine 5'-(tetrahydrogen triphosphate), P''→5'-ester with 2-amino-6,9-dihydro-7-methyl-6-oxo-9-β-D-ribofuranosyl-1H-purinium inner salt, sodium salt; m7Gp3G sodium salt; m7GpppG sodium salt; mCAP sodium salt. Grade: ≥95% by HPLC. Molecular formula: C21H29N10O18P3 (free acid). Mole weight: 802.43 (free acid).
m7GTP-γ-aminophenyl-PEG4-Biotin
m7GTP-γ-aminophenyl-PEG4-Biotin is a groundbreaking theoretical compound used in unraveling the intricate intricacies of mRNA capping and RNA processing. Synonyms: 7-Methylguanosine-5'-[γ-(4-aminophenyl)-PEG4]-5'-triphosphate-Biotin. Grade: ≥ 95 % by HPLC. Molecular formula: C38H58N9O21P3S (free acid). Mole weight: 1101.27 (free acid).
M871
M871 is a selective galanin GAL2 receptor antagonist with Ki values of 420 and 13.1 nM for GAL1 and GAL2 receptors respectively. It blocks the pro-nociceptive effect of GAL2 receptor agonists. Synonyms: Galanin(2-13)Glu-His-(Pro)3(Ala-Leu)2Ala-amide. Grade: >98%. CAS No. 908844-75-7. Molecular formula: C108H163N27O28. Mole weight: 2287.64.
Maduramicin Acid
Maduramicin Acid is a polyether antibiotic first isolated from actinomadura yunnaense (formerly nocardia sp. X-14868). It is a broad spectrum anti-coccidiosis agent, also active against treponema and cryptosporidium. It is also an ionic carrier, forming complexes with monovalent cations and having a higher affinity for K+ than Na+. Synonyms: α-Maduramicin; Maduramycin; X 14868A; CL 273703; LL-C 23024-A; Antibiotic X 14868A. Grade: >98% by HPLC. CAS No. 79356-08-4. Molecular formula: C47H80O17. Mole weight: 917.13.
Maduramicin Ammonium
Maduramcin ammonium is prepared from maduramicin by taking advantage of the acidic carboxylic acid which ionises and readily forms the salt in ammonium hydroxide solutions. The ammonium salt is the preferred formulation in animals to prevent coccidiosis. It is a polyether antibiotic chemically related to the Lonomycins. Uses: Anti-bacterial agents. Synonyms: Cygro; Maduramicin α, Monoammonium Salt; Prinicin Ammonium; CL 259971; Lonomycin A, 23,27-didemethoxy-2,6,22-tridemethyl-11-O-demethyl-22-((2,6-dideoxy-3,4-di-O-methyl-beta-L-arabino-hexopyranosyl)oxy)-6-methoxy-, monoammonium salt, (3R,4S,5S,6R,7S,22S)-. Grade: >95%. CAS No. 84878-61-5. Molecular formula: C47H83O17N. Mole weight: 934.16.
Magainin I
Magainin I is a peptide antibiotic with antibacterial and antiparasitic activities, originally extracted from the skin of Xenopus laevis. It has a broad spectrum of non-specific activity against a variety of microorganisms, including viruses, gram-positive and gram-negative bacteria, protozoa, yeast and fungi, and may also have hemolytic and cytotoxicity to cancer cells. Magainin 1 is a fungicide. Magainin 1 has an inhibitory effect on herpes simplex virus type 1 (HSV-1) and HSV-2. Synonyms: H-Gly-Ile-Gly-Lys-Phe-Leu-His-Ser-Ala-Gly-Lys-Phe-Gly-Lys-Ala-Phe-Val-Gly-Glu-Ile-Met-Lys-Ser-OH; glycyl-L-isoleucyl-glycyl-L-lysyl-L-phenylalanyl-L-leucyl-L-histidyl-L-seryl-L-alanyl-glycyl-L-lysyl-L-phenylalanyl-glycyl-L-lysyl-L-alanyl-L-phenylalanyl-L-valyl-glycyl-L-alpha-glutamyl-L-isoleucyl-L-methionyl-L-lysyl-L-serine; Magainin 1 peptide, Xenopus. Grade: >95%. CAS No. 108433-99-4. Molecular formula: C112H177N29O28S. Mole weight: 2409.85.
Magainin II
Magainin II is a broad-spectrum antibiotic isolated from Xenopus laevis. It has anti-fungal and anti-cancer activity in vitro. Synonyms: Magainin 2; magainin 2 peptide, Xenopus; Z-12 Peptide; Mag-2; Magainin I, 10-L-lysine-22-L-asparagine-; H-Gly-Ile-Gly-Lys-Phe-Leu-His-Ser-Ala-Lys-Lys-Phe-Gly-Lys-Ala-Phe-Val-Gly-Glu-Ile-Met-Asn-Ser-OH; glycyl-L-isoleucyl-glycyl-L-lysyl-L-phenylalanyl-L-leucyl-L-histidyl-L-seryl-L-alanyl-L-lysyl-L-lysyl-L-phenylalanyl-glycyl-L-lysyl-L-alanyl-L-phenylalanyl-L-valyl-glycyl-L-alpha-glutamyl-L-isoleucyl-L-methionyl-L-asparagyl-L-serine. Grade: ≥97% by HPLC. CAS No. 108433-95-0. Molecular formula: C114H180N30O29S. Mole weight: 2466.89.
Malantide, a highly specific substrate for PKA, is a synthetic dodecapeptide derived from the site phosphorylated by cAMP-dependent protein kinase (PKA) on the β-subunit of phosphorylase kinase. Synonyms: H-Arg-Thr-Lys-Arg-Ser-Gly-Ser-Val-Tyr-Glu-Pro-Leu-Lys-Ile-OH; L-arginyl-L-threonyl-L-lysyl-L-arginyl-L-seryl-glycyl-L-seryl-L-valyl-L-tyrosyl-L-alpha-glutamyl-L-prolyl-L-leucyl-L-lysyl-L-isoleucine. Grade: ≥95%. CAS No. 86555-35-3. Molecular formula: C72H124N22O21. Mole weight: 1633.89.
Malantide acetate
Malantide acetate, a highly specific substrate for PKA, is a synthetic dodecapeptide derived from the site phosphorylated by cAMP-dependent protein kinase (PKA) on the β-subunit of phosphorylase kinase. Synonyms: H-Arg-Thr-Lys-Arg-Ser-Gly-Ser-Val-Tyr-Glu-Pro-Leu-Lys-Ile-OH.CH3CO2H; L-arginyl-L-threonyl-L-lysyl-L-arginyl-L-seryl-glycyl-L-seryl-L-valyl-L-tyrosyl-L-alpha-glutamyl-L-prolyl-L-leucyl-L-lysyl-L-isoleucine acetic acid. Grade: ≥95%. Molecular formula: C74H128N22O23. Mole weight: 1693.97.
It is produced by the strain of Str. lydicus No. 15748. It is an antibiotic that inhibits Gram-negative bacteria by inhibiting peptidoglycan synthesis in bacterial cell walls and promoting the formation of spheroplasts. Synonyms: (R-(R*,S*))-(((2-Amino-3-methyl-1-oxobutyl)amino)oxy)butanedioic acid; Butanedioic acid, (((2-amino-3-methyl-1-oxobutyl)amino)oxy)-, (R-(R*,S*))-; (R)-[[[(S)-2-Amino-3-methyl-1-oxobutyl]amino]oxy]butanedioic acid. Grade: ≥95%. CAS No. 73020-27-6. Molecular formula: C9H16N2O6. Mole weight: 248.23.
Mambalgin 1
Mambalgin 1, a toxin isolated from black mamba venom, is a disulfide-rich polypeptide consisting of 57 amino acids and belongs to the family of three-finger toxins. Mambalgin 1 is a selective ASIC1a inhibitor (IC50= 192 and 72 nM for human ASIC1a and ASIC1a/1b dimer, respectively), and binds to closed/inactive channel. Synonyms: LKCYQHGKVVTCHRDMKFCYHNTGMPFRNLKLILQGCSSSCSETENNKCCSTDRCNK. Grade: >98%. CAS No. 1609937-15-6. Molecular formula: C272H429N85O84S10. Mole weight: 6554.51.
(+/-)-Mandelic Acid-[2,3,4,5,6-d5]
(+/-)-Mandelic Acid-[2,3,4,5,6-d5] is the labelled analogue of DL-Mandelic acid, which is an impurity of Pregabalin. Pregabalin is a medication used to treat epilepsy, neuropathic pain, fibromyalgia, and generalized anxiety disorder. Synonyms: α-Hydroxy-benzene-d5-acetic Acid. Grade: 98 atom % D. CAS No. 70838-71-0. Molecular formula: C8H3D5O3. Mole weight: 157.18.
Manumycin
It is produced by the strain of Str. parvullus ETH 25000. It has anti-gram-positive bacterial effect, and has weak antibacterial effect on some mycobacteria and candida. Synonyms: Manumycin A; NSC 622141; Antibiotic UCF 1C; 2,4-Decadienamide, N-[(1S,5S,6R)-5-hydroxy-5-[(1E,3E,5E)-7-[(2-hydroxy-5-oxo-1-cyclopenten-1-yl)amino]-7-oxo-1,3,5-heptatrienyl]-2-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl]-2,4,6-trimethyl-, (2E,4E,6R)-; (-)-Manumycin A; Antibiotic TMC 1F. Grade: ≥98%. CAS No. 52665-74-4. Molecular formula: C31H38N2O7. Mole weight: 550.64.
Marbofloxacin
Marbofloxacin is a third generation fluoroquinolone antibiotic. Marbofloxacin exhibits high bactericidal activity against a broad spectrum of aerobic Gram-negative and some Gram-positive bacteria, as well as Mycoplasma spp. Uses: Anti-bacterial agents. Synonyms: 9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[3,2,1-ij][4,1,2]benzoxadiazine-6-carboxylic Acid; Marbocyl; Zeniquin; Marbofloxacinum. Grade: >98%. CAS No. 115550-35-1. Molecular formula: C17H19FN4O4. Mole weight: 362.36.
Margatoxin
Margatoxin (MgTx) is a component of the venom of Scorpio Centruroides margaritatus. Margatoxin preferentially inhibits voltage-dependent potassium channels Kv1.3 with an IC50 value around 50 pM (20 fold more potent than Charybdotoxin) and irreversibly inhibits the proliferation response of human T-cells at 20 μM concentration. Uses: Potassium channel blockers. Synonyms: MgTX. Grade: >98%. CAS No. 145808-47-5. Molecular formula: C178H286N52O50S7. Mole weight: 4178.96.
Marizomib
Marizomib is a naturally-occurring salinosporamide, isolated from the marine actinomycete Salinospora tropica, with potential antineoplastic activity. Marizomib irreversibly binds to and inhibits the 20S catalytic core subunit of the proteasome by covalently modifying its active site threonine residues. Synonyms: (-)-Salinosporamide A; ML 858; ML858; ML-858; Marizomib; NPI 0052; NPI0052; NPI-0052; Salinosporamide A. Grade: ≥95%. CAS No. 437742-34-2. Molecular formula: C15H20ClNO4. Mole weight: 313.78.
MART-1 (26-35) human
MART-1 (26-35), an immunodominant antigen from melanocyte/melanoma (Melan-A/MART) protein, is amino acid residue 26 to 35 of MART-1 protein. Synonyms: Melanoma antigen recognized by T-cells 1 (26-35); MART-1(26-35)(A27L) peptide; Melan-A (26-35); H-Glu-Ala-Ala-Gly-Ile-Gly-Ile-Leu-Thr-Val-OH; L-alpha-glutamyl-L-alanyl-L-alanyl-glycyl-L-isoleucyl-glycyl-L-isoleucyl-L-leucyl-L-threonyl-L-valine. Grade: 98%. CAS No. 156251-01-3. Molecular formula: C42H74N10O14. Mole weight: 943.09.
Martinomycin
It is produced by the strain of Str. salvialis. It's a polyether antibiotic. It has strong anti-gram-positive bacteria activity, but no anti-gram-negative bacteria activity. It also acts as a pesticide. Synonyms: 2H-Pyran-2-acetic acid, 6-[[(2R,3R,4R,5S,7S,9R,10R)-3,9-dimethoxy-2,4,10-trimethyl-2-[(2S,2'R,5R,5'R)-octahydro-5'-[(2S,3S,4S,5R,6S)-tetrahydro-6-hydroxy-3,5,6-trimethyl-4-[[(2R,5S,6R)-tetrahydro-5-methoxy-6-methyl-2H-pyran-2-yl]oxy]-2H-pyran-2-yl][2,2'-bifuran]-5-yl]-1,6-dioxaspiro[4.5]dec-7-yl]methyl]tetrahydro-2-hydroxy-4,5-dimethoxy-a,3,5-trimethyl-, (aR,2S,3S,4S,5S,6S)-; AntibioticK 41, 2-deoxy-2-methyl-; 2H-Pyran-2-acetic acid, 6-[[3,9-dimethoxy-2,4,10-trimethyl-2-[octahydro-5'-[tetrahydro-6-hydroxy-3,5,6-trimethyl-4-[(tetrahydro-5-methoxy-6-methyl-2H-pyran-2-yl)oxy]-2H-pyran-2-yl][2,2'-bifuran]-5-yl]-1,6-dioxaspiro[4.5]dec-7-yl]methyl]tetrahydro-2-hydroxy-4,5-dimethoxy-a,3,5-trimethyl-, [2S-[2a,2(S*),3a,4b,5a,6b[2S*[2R*,2'S*,5S*,5'S*[2R*,3R*,4R*(2S*,5R*,6S*),5S*,6R*]],3S*,4S*,5R*,7R*,9S*,10S*]]]-. Grade: ≥95%. CAS No. 160791-16-2. Molecular formula: C49H84O17. Mole weight: 945.18.
Mas 7
Mas7, a structural analogue of mastoparan, is a G protein activator via Gαi and Gαo stimulation. Synonyms: Mastoparan 7; H-Ile-Asn-Leu-Lys-Ala-Leu-Ala-Ala-Leu-Ala-Lys-Ala-Leu-Leu-NH2; L-isoleucyl-L-asparagyl-L-leucyl-L-lysyl-L-alanyl-L-leucyl-L-alanyl-L-alanyl-L-leucyl-L-alanyl-L-lysyl-L-alanyl-L-leucyl-L-leucinamide; Mast cell degranulating peptide (Vespula lewisII), 12-L-alanine-13-L-leucine-; Mas7; Mas-7. Grade: ≥95%. CAS No. 145854-59-7. Molecular formula: C67H124N18O15. Mole weight: 1421.81.
Mastoparan
Mastoparan, a tetradecapeptide which is a component of wasp venom, activates Gi and Go and has been shown to cause an increase in the production of Arachidonic Acid catalyzed by PLA2 from porcine pancreas and bee venom. Synonyms: H-Ile-Asn-Leu-Lys-Ala-Leu-Ala-Ala-Leu-Ala-Lys-Lys-Ile-Leu-NH2; L-isoleucyl-L-asparagyl-L-leucyl-L-lysyl-L-alanyl-L-leucyl-L-alanyl-L-alanyl-L-leucyl-L-alanyl-L-lysyl-L-lysyl-L-isoleucyl-L-leucinamide. Grade: ≥95%. CAS No. 72093-21-1. Molecular formula: C70H131N19O15. Mole weight: 1478.91.
Mastoparan acetate
Mastoparan, a tetrapeptide, is a component of wasp venom that activates Gi and Go, and has been shown to increase the production of arachidonic acid catalyzed by PLA2 in porcine pancreas and bee venom. Synonyms: Mast cell degranulating peptide (Vespula lewisII) acetate; H-Ile-Asn-Leu-Lys-Ala-Leu-Ala-Ala-Leu-Ala-Lys-Lys-Ile-Leu-NH2.CH3CO2H; L-Leucinamide, L-isoleucyl-L-asparaginyl-L-leucyl-L-lysyl-L-alanyl-L-leucyl-L-alanyl-L-alanyl-L-leucyl-L-alanyl-L-lysyl-L-lysyl-L-isoleucyl-, acetate (1:1); Mastoparan 1 acetate. Grade: ≥95%. Molecular formula: C70H131N19O15.C2H4O2. Mole weight: 1538.99.
Mastoparan M tetraacetate
Mastoparan M exhibits antimicrobial activity against both Gram-positive and -negative bacteria as well as hemolytic activity on chicken, human, and sheep erythrocytes. It has a role as an antibacterial agent. Synonyms: L-Leucinamide, L-isoleucyl-L-asparaginyl-L-leucyl-L-lysyl-L-alanyl-L-isoleucyl-L-alanyl-L-alanyl-L-leucyl-L-alanyl-L-lysyl-L-lysyl-L-leucyl-, acetate (1:4); H-Ile-Asn-Leu-Lys-Ala-Ile-Ala-Ala-Leu-Ala-Lys-Lys-Leu-Leu-NH2.4CH3CO2H; L-isoleucyl-L-asparagyl-L-leucyl-L-lysyl-L-alanyl-L-isoleucyl-L-alanyl-L-alanyl-L-leucyl-L-alanyl-L-lysyl-L-lysyl-L-leucyl-L-leucinamide acetic acid. Grade: ≥95%. CAS No. 79396-78-4. Molecular formula: C70H131N19O15.4C2H4O2. Mole weight: 1719.12.
Mastoparan X
It is a G protein activator peptide that binds to Gi and Go. It also binds with high affinity to calmodulin (Kd~0.9 nM) and inhibits sarcoplasmic reticulum Ca2+-ATPase (Ki=4.4 mM). Synonyms: H-Ile-Asn-Trp-Lys-Gly-Ile-Ala-Ala-Met-Ala-Lys-Lys-Leu-Leu-NH2; L-isoleucyl-L-asparagyl-L-tryptophyl-L-lysyl-glycyl-L-isoleucyl-L-alanyl-L-alanyl-L-methionyl-L-alanyl-L-lysyl-L-lysyl-L-leucyl-L-leucinamide; mastoparan-V; MP-V; Mas X. Grade: ≥95% by HPLC. CAS No. 72093-22-2. Molecular formula: C73H126N20O15S. Mole weight: 1555.97.
Maxadilan
Maxadilan, a potent vasodilator isolated from the salivary glands of the sand fly Lutzomyia longipalpis, specifically and effectively activates the mammalian PAC1 receptor, one of the three receptors of PACAP. Synonyms: H-Cys-Asp-Ala-Thr-Cys-Gln-Phe-Arg-Lys-Ala-Ile-Asp-Asp-Cys-Gln-Lys-Gln-Ala-His-His-Ser-Asn-Val-Leu-Gln-Thr-Ser-Val-Gln-Thr-Thr-Ala-Thr-Phe-Thr-Ser-Met-Asp-Thr-Ser-Gln-Leu-Pro-Gly-Asn-Ser-Val-Phe-Lys-Glu-Cys-Met-Lys-Gln-Lys-Lys-Lys-Glu-Phe-Lys-Ala-NH2 (Disulfide bridge: Cys1-Cys5, Cys14-Cys51); Maxadilan (Lutzomyialongipalpis); L-cysteinyl-L-alpha-aspartyl-L-alanyl-L-threonyl-L-cysteinyl-L-glutaminyl-L-phenylalanyl-L-arginyl-L-lysyl-L-alanyl-L-isoleucyl-L-alpha-aspartyl-L-alpha-aspartyl-L-cysteinyl-L-glutaminyl-L-lysyl-L-glutaminyl-L-alanyl-L-histidyl-L-histidyl-L-seryl-L-asparagyl-L-valyl-L-leucyl-L-glutaminyl-L-threonyl-L-seryl-L-valyl-L-glutaminyl-L-threonyl-L-threonyl-L-alanyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-methionyl-L-alpha-aspartyl-L-threonyl-L-seryl-L-glutaminyl-L-leucyl-L-prolyl-glycyl-L-asparagyl-L-seryl-L-valyl-L-phenylalanyl-L-lysyl-L-alpha-glutamyl-L-cysteinyl-L-methionyl-L-lysyl-L-glutaminyl-L-lysyl-L-lysyl-L-lysyl-L-alpha-glutamyl-L-phenylalanyl-L-lysyl-L-alaninamide (1->5),(14->51)-bis(disulfide). Grade: 95%. CAS No. 135374-80-0. Molecular formula: C291H466N86O94S6. Mole weight: 6865.82.
Maytansinol
Maytansinol is an ansamacrolide isolated from P. verrucose. It was shown to inhibit microtubule assembly and induces microtubule disassembly in vitro. It exhibits antitumor activity. Synonyms: (3S)-3-O-De[2-(acetylmethylamino)-1-oxopropyl]-maytansine; Ansamitocin P-0; NSC239386; NSC-239386; Maytansine; Ansamitocin P 0; Antibiotic C 15003P; NSC 239386. Grade: 95%. CAS No. 57103-68-1. Molecular formula: C28H37ClN2O8. Mole weight: 565.06.
Mazdutide
Mazdutide is a long-acting glucagon-like peptide-1 (GLP-1) and glucagon receptor dual agonist. Mazdutide has been use in the research of type 2 diabetes mellitus (T2DM). Synonyms: IBI362; IBI 362; IBI-362; LY3305677; LY 3305677; LY-3305677; OXM3; OXM-3; OXM 3. CAS No. 2259884-03-0. Molecular formula: C207H317N45O65. Mole weight: 4476.
MCD Peptide
22-amino acid peptide with a strongly basic character and 2 disulfide bridges, , from Apis mellifera bee venom, a blocker of voltage-sensitive K+ channels with potent convulsant activity. Synonyms: Peptide 401; Mast Cell Degranulating (MCD) Peptide; Ile-Lys-Cys-Asn-Cys-Lys-Arg-His-Val-Ile-Lys-Pro-His-Ile-Cys-Arg-Lys-Ile-Cys-Gly-Lys-Asn-NH2 (Disulfide bridge: Cys3-Cys15, Cys5-Cys19); L-isoleucyl-L-lysyl-L-cysteinyl-L-asparagyl-L-cysteinyl-L-lysyl-L-arginyl-L-histidyl-L-valyl-L-isoleucyl-L-lysyl-L-prolyl-L-histidyl-L-isoleucyl-L-cysteinyl-L-arginyl-L-lysyl-L-isoleucyl-L-cysteinyl-glycyl-L-lysyl-L-asparaginamide (3->15),(5->19)-bis(disulfide). Grade: ≥95%. CAS No. 32908-73-9. Molecular formula: C110H192N40O24S4. Mole weight: 2587.22.
MCH (human, mouse, rat)
MCH is an endogenous melanin-concentration hormone receptor agonist with IC50 values of 0.3 and 1.5 nM at MCH1 and MCH2 receptors respectively. It can increase food intake in vivo. Synonyms: Melanin concentrating hormone, human, mouse, rat; Asp-Phe-Asp-Met-Leu-Arg-Cys-Met-Leu-Gly-Arg-Val-Tyr-Arg-Pro-Cys-Trp-Gln-Val. Grade: ≥95% by HPLC. CAS No. 128315-56-0. Molecular formula: C105H160N30O26S4. Mole weight: 2386.84.
MCL 0020
MCL 0020 is a selective melanocortin MC4 receptor antagonist with IC50 value of 11.63nM at MC4 receptor. It shows anxiolytic-like activity in vivo. Synonyms: MCL 0020; MCL0020; MCL-0020; N-Acetyl-3-(2-naphthalenyl)-D-alanyl-L-arginyl-3-(2-naphthalenyl)-L-alaninamide. Grade: >98%. CAS No. 475498-26-1. Molecular formula: C34H39N7O4. Mole weight: 609.73.
MDL 28170
MDL 28170 is a calpain and cathepsin B inhibitor with Ki values of 10 and 25 nM respectively. It shows neuroprotective effects in vivo. MDL 28170 can attenuate depression in myocardial contractile performance which occurs during reperfusion following cardiac ischemia. Synonyms: benzyl N-[(2S)-3-methyl-1-oxo-1-[(1-oxo-3-phenylpropan-2-yl)amino]butan-2-yl]carbamate. Grade: ≥ 95 % by HPLC. CAS No. 88191-84-8. Molecular formula: C22H26N2O4. Mole weight: 382.45.
MDL 29913
MDL 29913 is a selective NK2 tachykinin receptor antagonist which can be used in the treatment of IBS. Synonyms: MDL 29913; MDL29913; MDL-29913; 1,4,7,10,13,16-Hexaazacyclooctadecane, Cyclic Peptide Deriv.; N-(2-Amino-4-methylpentyl)?-N-methyl-L-leucyl-L-glutaminyl-L-tryptophyl-L-phenylalanylglycine (5→1)?-Lactam. Grade: >97%. CAS No. 135721-56-1. Molecular formula: C40H56N8O6. Mole weight: 744.92.
mDPR-Val-Cit-PAB-MMAE
mDPR-Val-Cit-PAB-MMAE consists the ADCs linker (mDPR-Val-Cit-PAB) and potent tubulin inhibitor (MMAE), mDPR-Val-Cit-PAB-MMAE is an antibody drug conjugate. Synonyms: N-[(2S)-3-Amino-2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanoyl]-L-valyl-N-{4-[(5S,8S,11S,12R)-11-[(2S)-2-butanyl]-12-(2-{(2S)-2-[(1R,2R)-3-{[(1S,2R)-1-hydroxy-1-phenyl-2-propanyl]amino}-1-methoxy-2 ; -methyl-3-oxopropyl]-1-pyrrolidinyl}-2-oxoethyl)-5,8-diisopropyl-4,10-dimethyl-3,6,9-trioxo-2,13-dioxa-4,7,10-triazatetradec-1-yl]phenyl}-N5-carbamoyl-L-ornithinamide; L-Ornithinamide, N-[(2S)-3-amino-2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxopropyl]-L-valyl-N5-(aminocarbonyl)-N-[4-[(5S,8S,11S,12R)-12-[2-[(2S)-2-[(1R,2R)-3-[[(1R,2S)-2-hydroxy-1-methyl-2-phenyl ethyl]amino]-1-methoxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl]-2-oxoethyl]-4,10-dimethyl-5,8-bis(1-methylethyl)-11-[(1S)-1-methylpropyl]-3,6,9-trioxo-2,13-dioxa-4,7,10-triazatetradec-1-yl]phenyl]-. Grade: ≥95%. CAS No. 1491152-26-1. Molecular formula: C65H100N12O15. Mole weight: 1289.561.
Mebendazole
Mebendazole is a benzimidazole anthelmintic and Tubulin-disrupting drug. It has antitumour activity in vitro and in vivo and inhibits growth and induces apoptosis. It is highly effective on various gastrointestinal nematodes in animals, has good effects on some tapeworms, and also effective on Trichinella spiralis. It is used for nematode diseases of horses, sheep, poultry and wild animals, nematodes and tapeworms of dogs and cats. Synonyms: Vermox; Telmin; Mebenvet; Pantelmin; Vermirax; Ovitelmin; Bantenol; Lomper; MBDZ; Besantin; Noverme; Methyl (5-benzoyl-1H-benzo[d]imidazol-2-yl)carbamate; Sufil; 5-Benzoyl-2-benzimidazolecarbamic acid methyl ester. Grade: >98%. CAS No. 31431-39-7. Molecular formula: C16H13N3O3. Mole weight: 295.29.
Meclocycline
Meclocycline is a tetracycline antibiotic derived from methacycline. It has a broad-spectrum antibacterial and antiprotozoan activity. Synonyms: GS-2989; NSC 78502; (4S,4aR,5S,5aR,12aS)-7-Chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methylene-1,11-dioxo-2-naphthacenecarboxamide; 7-Chloro-6-methylene-5-oxytetracycline; [4S-(4α,4aα,5α,5aα,12aα)]-7-Chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methylene-1,11-dioxo-2-naphthacenecarboxamide. Grade: ≥98%. CAS No. 2013-58-3. Molecular formula: C22H21ClN2O8. Mole weight: 476.86.
Meclocycline sulfosalicylate
Mecycline sulfosalicylate is a kind of tetracycline antibiotic, which shows broad-spectrum antibacterial and protozoal activity by combining 30S and 50S ribosomal subunits, preventing protein synthesis. Synonyms: Mecloderm; Meclan; Meclutin. Grade: >98% by HPLC. CAS No. 73816-42-9. Molecular formula: C29H27ClN2O14S. Mole weight: 695.05.
Megalomicin A
It is produced by the strain of Micromonospora megalomice var. megalomicea NRRL 3274. It is a macrolide antibiotic. It has anti-bacterial and mycobacterium activity, the activity is the strongest under alkaline condition, serum can reduce the activity of 20%-30%. It has protective effect on mice infected with Staphylococcus aureus, pneumococcus, E. coli and Pseudomonas aeruginosa. Synonyms: Megalomicin; Antibiotic XK 41C; Antibiotic W-847-A; Megalomicina; Megalomicine; Megalomicinum; [3R-(3R*,4S*,5S*,6R*,7R*,9R*,11R*,12R*,13S*,14R*)]-4-[(2,6-Dideoxy-3-C-methyl-a-L-ribo-hexopyranosyl)oxy]-14-ethyl-12,13-dihydroxy-3,5,7,9,11,13-hexamethyl-7-[[2,3,6-trideoxy-3-(dimethylamino)-a-L-ribo-hexopyranosyl]oxy]-6-[[3,4,6-trideoxy-3-(dimethylamino)-b-D-xylo-hexopyranosyl]oxy]oxacyclotetradecane-2,10-dione; Erythromycin, 3''-O-demethyl-6-O-[2,3,6-trideoxy-3-(dimethylamino)-a-L-ribo-hexopyranosyl]-. Grade: ≥95%. CAS No. 28022-11-9. Molecular formula: C44H80N2O15. Mole weight: 877.11.
Melanin Concentrating Hormone, salmon
Melanin Concentrating Hormone (MCH), salmon is a 19-amino acid neuropeptide, originally found in the pituitary gland of teleost fish, that regulates food intake, energy balance, sleep status and the cardiovascular system. MCH is a ligand for orphan G protein coupled receptor (SLC-1/GPR24) and MCHR2. Synonyms: MCH (salmon); Asp-Thr-Met-Arg-Cys-Met-Val-Gly-Arg-Val-Tyr-Arg-Pro-Cys-Trp-Glu-Val (Disulfide bridge: Cys5-Cys14); L-alpha-aspartyl-L-threonyl-L-methionyl-L-arginyl-L-cysteinyl-L-methionyl-L-valyl-glycyl-L-arginyl-L-valyl-L-tyrosyl-L-arginyl-L-prolyl-L-cysteinyl-L-tryptophyl-L-alpha-glutamyl-L-valine (5->14)-disulfide. Grade: ≥90%. CAS No. 87218-84-6. Molecular formula: C89H139N27O24S4. Mole weight: 2099.48.
Melanin Concentrating Hormone, salmon acetate
Melanin Concentrating Hormone, salmon acetate is a 19-amino acid neuropeptide, originally found in the pituitary gland of teleost fish, that regulates food intake, energy balance, sleep status and the cardiovascular system. MCH is a ligand for orphan G protein-coupled receptor (SLC-1/GPR24) and MCHR2. Synonyms: MCH (salmon) acetate; L-Valine, L-α-aspartyl-L-threonyl-L-methionyl-L-arginyl-L-cysteinyl-L-methionyl-L-valylglycyl-L-arginyl-L-valyl-L-tyrosyl-L-arginyl-L-prolyl-L-cysteinyl-L-tryptophyl-L-α-glutamyl-, cyclic (5→14)-disulfide acetate; Melanin-concentrating hormone (Oncorhynchus keta) acetate; Melanin-concentrating hormone (Carassius auratus) acetate; Melanin-concentrating hormone (Oncorhynchus keta reduced), cyclic (5→14)-disulfide acetate; Salmon melanin-concentrating hormone acetate; H-Asp-Thr-Met-Arg-Cys-Met-Val-Gly-Arg-Val-Tyr-Arg-Pro-Cys-Trp-Glu-Val-OH.CH3CO2H (Disulfide bridge: Cys5-Cys14); L-alpha-aspartyl-L-threonyl-L-methionyl-L-arginyl-L-cysteinyl-L-methionyl-L-valyl-glycyl-L-arginyl-L-valyl-L-tyrosyl-L-arginyl-L-prolyl-L-cysteinyl-L-tryptophyl-L-alpha-glutamyl-L-valine (5->14)-disulfide. Grade: ≥95%. Molecular formula: C91H143N27O26S4. Mole weight: 2159.55.
Melanotan I
A synthetic analogue of α-melanocyte stimulating hormone (α-MSH). Synonyms: Afamelanotide acetate; (Nle4,D-Phe7)-α-MSH; NDP-MSH. Grade: ≥95% by HPLC. CAS No. 75921-69-6. Molecular formula: C78H111N21O19. Mole weight: 1646.85.
Melanotan (MT)-II
Melanotan II is a potent full agonist of melanocortin-3 and melanocortin-4 receptors (Ki= 6.6, 34 for MC4, MC3 receptors respectively). Melanotan II stimulates erectile activity, and inhibits food intake and displays neuroprotective properties in vivo. Synonyms: Melanotan II; MTII, Bremelanotide amide; Melanotan-II; MelanotanII; Ac-[Nle4Asp5D-Phe7Lys10]α-MSH-(4-10)-NH2; Ac-Nle-Asp-His-d-Phe-Arg-Trp-Lys-NH2, (2→7)-lactam. Grade: 98%. CAS No. 121062-08-6. Molecular formula: C50H69N15O9. Mole weight: 1024.18.
Meleagrin
Meleagrin is an alkaloid antibiotic isolated from a number of species of penicillium with antitumor, anti-proliferative and antibacterial activity. It inhibits the growth of S. aureus, E. coli and S. pneumoniae. Meleagrin is a class of FabI inhibitor, and a lead c-Met inhibitory entity useful for the control of c-Met-dependent metastatic and invasive breast malignancies. Synonyms: 6-O-Methyloxaline; Meleagrine; (3E,7aR,12aS)-7a-(1,1-Dimethyl-2-propenyl)-7a,12-dihydro-6-hydroxy-3-(1H-imidazol-4-ylmethylene)-12-methoxy-1H,5H-imidazo[1',2':1,2]pyrido[2,3-b]indole-2,5(3H)-dione; [7aR-(3E,7aR*,12aS*)]-7a-(1,1-Dimethyl-2-propenyl)-7a,12-dihydro-6-hydroxy-3-(1H-imidazol-4-ylmethylene)-12-methoxy-1H,5H-imidazo[1',2':1,2]pyrido[2,3-b]indole-2,5(3H)-dione. Grade: >98% by HPLC. CAS No. 71751-77-4. Molecular formula: C23H23N5O4. Mole weight: 433.46.
Melittin
Melittin is an oligopeptide constituent discovered within the venom of bees, showcasing remarkable characteristics encompassing its effectiveness against microbes, viruses and cancer cells. Its capacity to assail cellular membranes renders Melittin a prospective tool in studying an array of ailments such as cancer, HIV and drug-resistant infections. Synonyms: melittinfrombeevenomsequencing*grade; melittinhoneybeevenom; melittin-t; H-GLY-ILE-GLY-ALA-VAL-LEU-LYS-VAL-LEU-THR-THR-GLY-LEU-PRO-ALA-LEU-ILE-SER-TRP-ILE-LYS-ARG-LYS-ARG-GLN-GLN-NH2. CAS No. 37231-28-0. Molecular formula: C131H229N39O31. Mole weight: 2846.46.
Melittin (honeybee)
Melittin is a polypeptide isolated from the venom of the honey bee (Apis mellifera). It inhibits protein kinase C, Ca2+/calmodulin-dependent protein kinase II, myosin light chain kinase and Na+/K+-ATPase (synaptosomal membrane). Synonyms: Honeybee melittin; Bee venom melittin; Forapin; H-Gly-Ile-Gly-Ala-Val-Leu-Lys-Val-Leu-Thr-Thr-Gly-Leu-Pro-Ala-Leu-Ile-Ser-Trp-Ile-Lys-Arg-Lys-Arg-Gln-Gln-NH2; glycyl-L-isoleucyl-glycyl-L-alanyl-L-valyl-L-leucyl-L-lysyl-L-valyl-L-leucyl-L-threonyl-L-threonyl-glycyl-L-leucyl-L-prolyl-L-alanyl-L-leucyl-L-isoleucyl-L-seryl-L-tryptophyl-L-isoleucyl-L-lysyl-L-arginyl-L-lysyl-L-arginyl-L-glutaminyl-L-glutaminamide. Grade: ≥98%. CAS No. 20449-79-0. Molecular formula: C131H229N39O31. Mole weight: 2846.46.