BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| IL-1 alpha Protein, Human (Biotinylated, HEK293, Avi) | IL-1α is a pro-inflammatory cytokine of the interleukin 1 family that plays an important role in inflammation and bridges the innate and adaptive immune systems. IL-1α is produced mainly by activated macrophages, as well as neutrophils, epithelial cells, and endothelial cells. IL-1α is a major agonist of IL-1 and mediates the activation of NF-kappa-B and the three MAPK pathways p38, p42/p44, and JNK pathways. IL-1α acts as an 'alarmin' and as a primum movens of tissue inflammation. IL-1 alpha protein, Human (Biotinylated, HEK293, Avi) is a biotinylated recombinant protein with Avi label that consists of 159 amino acids (S113-A271) and is produced by E. coli. Synonyms: Interleukin-1 Alpha; IL-1 Alpha; Hematopoietin-1; IL1A; IL1F1; IL-1a. Grade: ≥95%. Mole weight: ~19 kDa. |  |
| IL-1 beta Protein, Human (Biotinylated, His-Avi) | IL-1β is a potent proinflammatory cytokine of the interleukin 1 family that is produced by activated macrophages, monocytes, and a subset of dendritic cells known as slanDC. IL-1β is an important mediator of the inflammatory response and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. IL-1 beta Protein, Human (Biotinylated, His-Avi), a Biotinylated IL-1 beta protein consisting of 153 amino acids (A117-S269), is produced in E. coli with His-tag and Avi-tag. Synonyms: Interleukin-1 beta; IL-1 beta; IL1F2; IL1B; IL-1BETA; IL1F2; IL-1β; IL-1 beta; IL-1B; Interleukin-1β. Grade: ≥95%. Mole weight: ~20.1 kDa. | |
| IL-21 Protein, Mouse (Biotinylated, His-Avi) | Interleukin-21 (IL-21) is a pleiotropic cytokine that acts on a wide range of lymphocytes, myeloid cells, and epithelial cells. These effects include effects on cell proliferation, survival, differentiation, and function. IL-21 is produced by activated CD4+ T cells, and acts on natural killer cells, CD4+ cells, and B cells to induce and sustain antibody production and mediate antibody class switching. IL-21 promotes a range of autoimmune diseases, including systemic lupus erythematosus, type 1 diabetes, multiple sclerosis, inflammatory bowel disease, and psoriasis. Synonyms: Interleukin-21; IL-21; Za11; CVID11. Grade: ≥95%. Mole weight: ~17.9 kDa. | |
| IL-23 alpha (170a.a) & IL-12 beta (306a.a) Heterodimer Protein, Human (Biotinylated, HEK293, His) | Interleukin 23 (IL-23) is a heterodimeric cytokine composed of an IL-12B (IL-12p40) subunit (which is shared with IL-12) and an IL-23A (IL-23p19) subunit. IL-23 binds to a heterodimer receptor composed of IL-12RB1 and IL-23R, activating the Jak-Stat signaling cascade and preferentially acting on memory CD4(+) T cells. Synonyms: IL-23 p19/IL-12 p40; IL23; IL-23A; Interleukin 23; SGRF. Grade: ≥90%. Mole weight: ~55.8 kDa. | |
| IL-23 alpha (170a.a) & IL-12 beta (306a.a) Heterodimer Protein, Human (Biotinylated, HEK293, His-Avi) | Interleukin 23 (IL-23) is a heterodimeric cytokine composed of an IL-12B (IL-12p40) subunit (which is shared with IL-12) and an IL-23A (IL-23p19) subunit. IL-23 binds to a heterodimer receptor composed of IL-12RB1 and IL-23R, activating the Jak-Stat signaling cascade and preferentially acting on memory CD4(+) T cells. Synonyms: IL23 alpha; IL12 beta; IL23 alpha&IL12 beta; IL12 β; IL23 alpha&IL12 β; IL-23A&IL-12B; IL23A&IL12B. Grade: ≥95%. Mole weight: ~24 kDa (IL-23 alpha) & 40-50 kDa (IL-12 beta). | |
| IL-23 alpha Protein, Mouse (Biotinylated, HEK293, His-Avi) | Interleukin 23 (IL-23) is a heterodimeric cytokine composed of an IL-12B (IL-12p40) subunit (which is shared with IL-12) and an IL-23A (IL-23p19) subunit. IL-23 is a member of the IL-12 cytokine family that has a pro-inflammatory effect and promotes angiogenesis. IL-23 stabilizes RORγt, thereby enabling Th17 cells to release their effector cytokines, such as IL-17, IL-21, IL-22, and GM-CSF, which mediate protection against extracellular fungi and bacteria and participate in barrier immunity. IL-23 also induces the proliferation of CD4 memory T cells (but not naive T cells). Synonyms: Interleukin-23 subunit alpha; IL-23 subunit alpha; IL-23-A; Interleukin-23 subunit p19; IL-23p19; IL23p19; IL23A; P19; SGRF. Grade: ≥95%. Mole weight: 23-28 kDa. | |
| IL-25/IL-17E Protein, Human (Biotinylated, HEK293, His-Avi) | Interleukin-25 (IL-25), also known as IL-17E, induces the expression of IL-4, IL-5, IL-13, TGF-β, and G-CSF. In non-immune cells, IL-25 can stimulate cell proliferation, inhibit cell apoptosis, produce inflammatory cytokines and chemokines, and regulate cell-cell adhesion and cell movement. IL-25 activates the NF-κB, MAPKs, and JAK/STAT signaling pathways. IL-25 is an important molecule that controls intestinal immunity and is involved in chronic inflammation associated with the gastrointestinal tract. IL-25 has potent anti-tumor activity in vivo against several human cancers, including melanoma, breast, lung, colon, and pancreatic cancers. Synonyms: IL-25; IL-17E; IL17E; Interleukin-17E; Interleukin-25. Grade: ≥95%. Mole weight: 25-35 kDa. | |
| IL-2 Protein, Human (Biotinylated, HEK293, His-Avi) | Interleukin 2 (IL-2) is a member of the IL-2 related family that functions to stimulate T-cell growth through the IL-2 receptor. IL-2 is a cytokine signaling molecule in the immune system that regulates the activity of white blood cells (white blood cells, usually lymphocytes) responsible for immunity. IL-2 mediates its action by binding to IL-2 receptors, which are expressed by lymphocytes. IL-2 has been used to treat renal cell carcinoma and metastatic melanoma. Synonyms: Interleukin-2; T-Cell Growth Factor; TCGF; Aldesleukin; IL2. Grade: ≥95%. Mole weight: 16-18 kDa. | |
| IL-2 Protein, Mouse (Biotinylated, HEK293, His-Avi) | Interleukin 2 (IL-2) is a member of the IL-2 related family that functions to stimulate T-cell growth through the IL-2 receptor. IL-2 is a cytokine signaling molecule in the immune system that regulates the activity of white blood cells (white blood cells, usually lymphocytes) responsible for immunity. IL-2 mediates its action by binding to IL-2 receptors, which are expressed by lymphocytes. IL-2 has been used to treat renal cell carcinoma and metastatic melanoma. Synonyms: IL2; T-cell growth factor; TCGF; Aldesleukin. Grade: ≥95%. Mole weight: 27-30 kDa. | |
| IL-4 Protein, Human (Biotinylated) | Interleukin-4 (IL-4) is a receptor for IL-4 RA that induces the differentiation of naive helper T cells (Th0 cells) into Th2 cells. IL-4 is mainly produced by mast cells, Th2 cells, eosinophils, and basophils. IL-4 is a pluripotent cytokine involved in humoral immunity and adaptive immune regulation. IL-4 stimulates the proliferation of activated B cells and T cells, and the differentiation of B cells into plasma cells. IL-4 reduces the production of Th1 cells, macrophages, IFNγ, and dendritic cells IL-12. Synonyms: Interleukin-4; IL-4; B-cell stimulatory factor 1; BSF-1. Grade: ≥90%. Mole weight: ~17.8 kDa. | |
| IL-4 Protein, Human (Biotinylated, HEK293, His-Avi) | Interleukin-4 (IL-4) is a receptor for IL-4 RA that induces the differentiation of naive helper T cells (Th0 cells) into Th2 cells. IL-4 is mainly produced by mast cells, Th2 cells, eosinophils, and basophils. IL-4 is a pluripotent cytokine involved in humoral immunity and adaptive immune regulation. IL-4 stimulates the proliferation of activated B cells and T cells, and the differentiation of B cells into plasma cells. IL-4 reduces the production of Th1 cells, macrophages, IFNγ, and dendritic cells IL-12. Synonyms: IL4; IL-4; Interleukin 4; MGC79402; Pitrakinra; B cell growth factor 1; BCDF; BCGF1; BCGF-1; Binetrakin; BSF1; BSF-1; BSF-1. Grade: ≥95%. Mole weight: 23-25 kDa. | |
| IL-5 Protein, Human (Biotinylated, HEK293, His-Avi) | Interleukin-5 (IL-5), an interleukin produced by type 2 T helper cells and mast cells, upregulates IL-2Rα on B cells, enhances IgA production, and stimulates the growth and differentiation of B cells and CTLs. By binding to the interleukin-5 receptor, IL-5 stimulates B cell growth and increases immunoglobulin (mainly IgA) secretion. IL-5 is a member of the helical bundle cytokine family, along with IL-3, IL-4, and granulocyte-macrophage colony-stimulating factor (GM-CSF). IL-5 is a homodimer factor that acts primarily on the eosinophilic arm of the Th2 response, promoting the survival, differentiation, and chemotaxis of these cells. Synonyms: Interleukin-5; B-cell differentiation factor I; Eosinophil differentiation factor; T-cell replacing factor; TRF; IL5. Grade: ≥95%. Mole weight: 18-24 kDa. | |
| IL-5 Protein, Mouse (Biotinylated, HEK293, His-Avi) | Interleukin-5 (IL-5), an interleukin produced by type 2 T helper cells and mast cells, upregulates IL-2Rα on B cells, enhances IgA production, and stimulates the growth and differentiation of B cells and CTLs. By binding to the interleukin-5 receptor, IL-5 stimulates B cell growth and increases immunoglobulin (mainly IgA) secretion. IL-5 is a member of the helical bundle cytokine family, along with IL-3, IL-4, and granulocyte-macrophage colony-stimulating factor (GM-CSF). IL-5 is a homodimer factor that acts primarily on the eosinophilic arm of the Th2 response, promoting the survival, differentiation, and chemotaxis of these cells. Synonyms: Interleukin-5; IL-5; T-cell replacing factor; TRF; EDF. Grade: ≥95%. Mole weight: 16-35 kDa. | |
| IL-6 (88-121) (human) | IL-6 (88-121) competitively inhibits the binding of human IL-6 to its receptor by interacting with the IL-6 receptor to a significant degree. Synonyms: H-ILE-ILE-THR-GLY-LEU-LEU-GLU-PHE-GLU-VAL-TYR-LEU-GLU-TYR-LEU-GLN-ASN-ARG-PHE-GLU-SER-SER-GLU-GLU-GLN-ALA-ARG-ALA-VAL-GLN-MET-SER-THR-LYS-OH; interleukin-6 fragment 88-121. Grade: 95%. CAS No. 145990-81-4. Molecular formula: C179H281N45O58S. Mole weight: 4023.47. | |
| [Ile5]-Angiotensin II (3-8) | [Ile5]-Angiotensin II (3-8) is a less effective agonist of the angiotensin AT1 receptor. Synonyms: Human angiotensin IV; Ile3-angiotensin IV; 1-De-asp-2-de-arg-5-ile-angiotensin II; (Des(Asp1,Arg2)-Ile5)angiotensin II; H-Val-Tyr-Ile-His-Pro-Phe-OH; 3-8-Angiotensin II, 5-L-isoleucine-; 5-L-Isoleucine-3-8-angiotensin II; Alanine, 3-phenyl-N-[1-[N-[N-(N-L-valyl-L-tyrosyl)-L-isoleucyl]-L-histidyl]-L-prolyl]-; Alanine, 3-phenyl-N-[1-[N-[N-(N-valyltyrosyl)isoleucyl]histidyl]prolyl]-; Angiotensin II, 1-de-L-aspartic acid-2-de-L-arginine-5-L-isoleucine-; Angiotensin IV, 3-L-isoleucine-; (3-8)-5-Isoleucine-angiotensin II; (Isoleucine5)-angiotensin II hexapeptide; 1-De-L-aspartic-2-de-L-arginine-5-L-isoleucineangiotensin II; 3-8-(5-Ile)-angiotensin-II; [Des-Asp1,des-Arg2,Ile5]-angiotensin II; Angiotensin IV; Human angiotensin hexapeptide(3-8); Human angiotensin(3-8). Grade: ≥95%. CAS No. 23025-68-5. Molecular formula: C40H54N8O8. Mole weight: 774.91. | |
| [Ile5]-Angiotensin II (3-8) TFA | [Ile5]-Angiotensin II (3-8) TFA is a less effective agonist of the angiotensin AT1 receptor. Synonyms: H-Val-Tyr-Ile-His-Pro-Phe-OH.TFA; L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-prolyl-L-phenylalanine trifluoroacetic acid; 5-L-Isoleucine-3-8-angiotensin II trifluoroacetate salt; (3-8)-5-Isoleucine-angiotensin II trifluoroacetate salt; Ile3-angiotensin IV trifluoroacetate salt; [Ile5]-angiotensin II (3-8) trifluoroacetate salt; Angiotensin IV TFA. Grade: ≥95%. Molecular formula: C40H54N8O8.C2HF3O2. Mole weight: 888.94. | |
| Ile-Pro-Pro | H-Ile-Pro-Pro-OH is an angiotensin-converting enzyme (ACE) inhibitor with an IC50 of 5 μM. Synonyms: H-Ile-Pro-Pro-OH; IPP, ACE-I Inhibitor. Grade: >98%. CAS No. 26001-32-1. Molecular formula: C16H27N3O4. Mole weight: 325.40. | |
| Illudin M | Illudin M is a natural sesquiterpene agent with strong anti-tumour activity. Synonyms: (-)-Illudin M; (3'S-trans)-2',3'-Dihydro-3'b,6'a-dihydroxy-2',2',4',6'-tetramethylspiro(cyclopropane-1,5'-(5H)inden)-7'(6'H)-one; (-)-1alpha,7beta-dihydroxy-2,9-illudadien-8-one. Grade: ≥95%. CAS No. 1146-04-9. Molecular formula: C15H20O3. Mole weight: 248.32. | |
| Illudin S | Illudin S is a natural sesquiterpene agent with strong anti-tumour activity. Illudin S inhibits DNA synthesis via an unknown mechanism. Synonyms: (-)-Illudin S; Lampterol; Lunamycin; (-)-1alpha,7beta,12-trihydroxy-2,9-illudadien-8-one; 2',3'-Dihydro-2',6'-dihydroxy-2'-(hydroxymethyl)-2',4',6'-trimethylspiro(cyclopropane-1,5'-(5H)inden)-7'(6'H)-one. Grade: >98% by HPLC. CAS No. 1149-99-1. Molecular formula: C15H20O4. Mole weight: 264.32. | |
| Imatinib | Imatinib inhibits the SLF-dependent activation of wild-type c-kit kinase activity with an IC50 for these effects of approximately 0.1 μM, which is similar to the concentration required for inhibition of PDGFR. Imatinib is an oral chemotherapy agent used to treat cancers. Specifically, it is used for chronic myelogenous leukemia (CML) and acute lymphocytic leukemia (ALL) that are Philadelphia chromosome-positive (Ph+), certain types of gastrointestinal stromal tumors (GIST), hypereosinophilic syndrome (HES), chronic eosinophilic leukemia (CEL), systemic mastocytosis, and myelodysplastic syndrome. Synonyms: CGP057148B; STI571; Gleevec; Glivec; N-(4-Methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)-4-((4-methylpiperazin-1-yl)methyl)benzamide; 4-[(4-Methyl-1-piperazinyl)methyl]-N-(4-methyl-3-{[4-(3-pyridinyl)-2-pyrimidinyl]amino}phenyl)benzamide. Grade: >98%. CAS No. 152459-95-5. Molecular formula: C29H31N7O. Mole weight: 493.60. | |
| (+/-)-Imazalil-[d5] Sulfate | (+/-)-Imazalil-[d5] Sulfate, is the labelled analogue of Imazalil. Imazalil, is a fungicide widely used in agriculture, particularly in the growing of citrus fruits. Synonyms: Imazalil-d5 Sulfate; 1-[2-(2,4-Dichlorophenyl)-2-[2-(propen-1-yl-d5)oxy]ethyl]-1H-imidazole Sulfate; 1-[2-(2,4-Dichlorophenyl)-2-[2-(propenyl-d5)oxy]ethyl]-1H-imidazole Sulfate; Chloramizol-d5 Sulfate; Microban Additive IF 4-d5; R 27180-d5. Grade: 95% by HPLC; 98% atom D. CAS No. 1398065-92-3. Molecular formula: C14H11D5Cl2N2O5S. Mole weight: 400.28. | |
| Imidazole | An impurity of Ondansetron, which is a serotonin 5-HT3 receptor antagonist used mainly as an antiemetic. Synonyms: Ondansetron EP Impurity E; Glyoxaline; 1,3-Diaza-2,4-cyclopentadiene; 1,3-Diazole; 3-Azapyrrole; Curezol SIZ; Glyoxalin; Imidazol; Imutex; Methanimidamide, N,N'-1,2-ethenediyl-; Miazole. Grade: ≥95%. CAS No. 288-32-4. Molecular formula: C3H4N2. Mole weight: 68.08. | |
| Imipenem Monohydrate | Imipenem is an intravenous β-lactam antibiotic. It is the first member of the carbapenem class of antibiotics. Imipenem is discovered via a lengthy trial-and-error search for a more stable version of the natural product thienamycin, which is produced by the bacterium Streptomyces cattleya. Imipenem has a broad spectrum of activity against aerobic and anaerobic, Gram-positive and Gram-negative bacteria. It is particularly important for its activity against Pseudomonas aeruginosa and the Enterococcus species, but it is not active against MRSA. Uses: Anti-bacterial agents. Synonyms: (5R,6S)-6-[(1R)-1-hydroxyethyl]-3-[[2-[(iminomethyl)amino]ethyl]thio]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, monohydrate; N-Formimidoyl Thienamycin; MK-787; MK 787; MK787. Grade: 98%. CAS No. 74431-23-5. Molecular formula: C12H17N3O4S.H2O. Mole weight: 317.36. | |
| Indanomycin | Indanomycin is an antibiotic of the pyrroloketoindane class produced by Streptomyces sp. It is an unusual pyrollic ionophore that is active against gram-positive bacteria and insects. It has antihypertensive properties. It is a growth promoter in ruminants. Synonyms: X-14547A; X 14547A; 2H-Pyran-2-acetic acid, 6-(1-ethyl-4-(1-ethyl-2,3,3a,4,5,7a-hexahydro-4-(1H-pyrrol-2-ylcarbonyl)-1H-inden-5-yl)-1,3-butadienyl)tetrahydro-alpha, 5-dimethyl-, (1S-(1-alpha,3-alpha,beta,4-beta,5-beta(1E(2S*(S*),5R*,6S*),3E),7a-alpha))-; Antibiotic X-14547A. Grade: >95% by HPLC. CAS No. 66513-28-8. Molecular formula: C31H43NO4. Mole weight: 493.68. | |
| Indole-3-carbinol | Indole-3-carbinol is an inhibitor of cell growth via suppressing incorporation of [3H]thymidine, triggering G1 cell cycle arrest and downregulation of cyclin-dependent kinase 6 (CDK6) expression. It exhibits anticancer activity by inhibition of NF-κB and Akt signaling pathways. Nutritional supplement in health care products. Synonyms: 3-Indolemethanol; (1H-Indol-3-yl)methanol; Indole-3-methanol; Indol-3-yl-methanol; 3-Hydroxymethylindole; I3C; Indinol. Grade: 98%. CAS No. 700-06-1. Molecular formula: C9H9NO. Mole weight: 147.17. | |
| Indolicidin | Indolicidin is the smallest of the naturally known occurring linear antimicrobial peptides, containing the highest percentage of tryptophan of any known protein, and consists of only six different amino acids. Indolicidin has been shown to be a fairly potent antimicrobial peptide with activity against a variety of microorganisms, fungi, and protozoa. Uses: Anti-infective agents. Synonyms: cationic antimicrobial peptide; H-Ile-Leu-Pro-Trp-Lys-Trp-Pro-Trp-Trp-Pro-Trp-Arg-Arg-NH2; L-isoleucyl-L-leucyl-L-prolyl-L-tryptophyl-L-lysyl-L-tryptophyl-L-prolyl-L-tryptophyl-L-tryptophyl-L-prolyl-L-tryptophyl-L-arginyl-L-argininamide. Grade: >98%. CAS No. 140896-21-5. Molecular formula: C100H132N26O13. Mole weight: 1906.28. | |
| Indolmycin | A highly selective antibiotic which acts as a tryptophan anti-metabolite; active against mycobacteria and H. Pylori, and can stimulate transcription in escherichia coli. Synonyms: Indolemycin; PA 155 A; (-)-indolmycin; (1R,5S)-(-)-5-(1-Indol-3-ylethyl)-2-(methylamino)-2-oxazolin-4-one. Grade: >99% by HPLC (total diastereoisomers). CAS No. 21200-24-8. Molecular formula: C14H15N3O2. Mole weight: 257.29. | |
| Indomethacin | A nonselective COX1 and COX2 inhibitor with IC50 of 0.1 μg/mL and 5 μg/mL, respectively. Synonyms: indomethacin; 53-86-1; indometacin; Indocin; Indomethacine; Indometacine; Indocid; Reumacide; Indomethazine; Metindol; Artrinovo; Confortid; Idomethine; Indomecol; Indomethacinum; Metartril; Methazine; Artrivia; Dolovin; Imbrilon; Indacin; Indomed; Indomee; Indoptol; Infrocin; Metacen; Sadoreum; Amuno; Inacid; Tannex; Indo-rectolmin; Inteban sp; Artracin; Durametacin; Indoptic; Inflazon; Mikametan. Grade: 98%. CAS No. 53-86-1. Molecular formula: C18H18O2. Mole weight: 266.3. | |
| Indomethacin Morpholinylamide | BML-190 is a selective cannabinoid CB2 receptor inverse agonist with Ki of 435 nM, with 50-fold selectivity over CB1 receptor. Synonyms: BML-190; BML 190; BML190; LM-4131; LM4131; LM 4131; IMMA; Indomethacin Morpholinylamide; 1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1-[2-(4-morpholinyl)-2-oxoethyl]-1H-indole. Grade: >98%. CAS No. 2854-32-2. Molecular formula: C23H23ClN2O4. Mole weight: 426.89. | |
| Indoximod | A methylated tryptophan with immune checkpoint inhibitory activity. Indoximod inhibits the enzyme indoleamine 2,3-dioxygenase (IDO), which degrades the essential amino acid tryptophan, and may increase or maintain tryptophan levels important to T cell function. Tryptophan depletion is associated with immunosuppression involving T cell arrest and anergy. Synonyms: NLG8189; NLG 8189; NLG-8189; D-1MT; 1-methyl-D-tryptophan; H-D-Trp(Me)-OH. Grade: > 98%. CAS No. 110117-83-4. Molecular formula: C12H14N2O2. Mole weight: 218.25. | |
| Inosine-5'-diphosphate trisodium salt | Inosine 5'-diphosphate trisodium salt is a pivotal constituent in the biomedical field, serving as a precursor for crucial molecules engaged in cellular processes. Its applied scope encompasses the synthesis of paramount compounds pertinent to studying viral invasions, immune disorders, and select cancerous conditions. Synonyms: 5'-IDP Na3; Inosine-5'-diphosphate, trisodium salt; Inosine 5'-(trihydrogen diphosphate), sodium salt (1:3); Inosine 5'-(trihydrogen diphosphate), trisodium salt; Inosine diphosphate trisodium salt; Inosine pyrophosphate trisodium salt; 5'-IDP trisodium salt; IDP trisodium salt. Grade: ≥98% by HPLC. CAS No. 71672-86-1. Molecular formula: C10H11N4Na3O11P2. Mole weight: 494.13. | |
| Inosine 5'-diphosphate trisodium salt monohydrate | Inosine 5'-diphosphate trisodium salt monohydrate is a pivotal constituent in the biomedical field, serving as a precursor for crucial molecules engaged in cellular processes. Its applied scope encompasses the synthesis of paramount compounds pertinent to studying viral invasions, immune disorders, and select cancerous conditions. Synonyms: Inosine 5'-(trihydrogen diphosphate), trisodium salt, monohydrate; Inosine 5'-(trihydrogen diphosphate), sodium salt, hydrate (1:3:1); Inosine diphosphate trisodium salt, monohydrate; Inosine pyrophosphate trisodium salt, monohydrate; 5'-IDP trisodium salt, monohydrate; IDP trisodium salt, monohydrate. Grade: ≥93% by HPLC. CAS No. 81012-88-6. Molecular formula: C10H11N4Na3O11P2.H2O. Mole weight: 512.15. | |
| Inosine 5'-triphosphate trisodium salt | Inosine-5'-triphosphate, an inosine nucleotide, is an intermediate in the purine metabolism pathway. Synonyms: Inosine 5'-(Tetrahydrogen Triphosphate) Trisodium Salt; NSC 20266; Trisodium Inosine-5'-triphosphate; ITP; 9H-Purin-6-ol, 9-[5-O-[hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-β-D-ribofuranosyl]-, sodium salt (1:3); Trisodium 5'-O-[({[(hydroxyphosphinato)oxy]phosphinato}oxy)phosphinato]inosine. Grade: ≥97% by HPLC. CAS No. 35908-31-7. Molecular formula: C10H12N4O14P3.3Na. Mole weight: 574.11. | |
| Ins(1,3,4,5)P4 Biotin | Ins(1,3,4,5)P4 Biotin is an analog of Ins(1,3,4,5)P4 labelled with biotin through a three-carbon linker at the 1-position on the inositol ring. Inositol phosphates are important signaling molecules involved in numerous cellular functions. Synonyms: Inositol 1,3,4,5-tetrakisphosphate Biotin. Grade: >95%. Molecular formula: C25H41N4Na7O21P4S. Mole weight: 1050.49. | |
| Ins(1,4,5)P3 Biotin | Ins(1,4,5)P3 Biotin is an analog of Ins(1,4,5)P3 labelled with biotin through a three-carbon linker at the 1-position on the inositol ring. Inositol phosphates are important signaling molecules involved in numerous cellular functions. Synonyms: Inositol 1,4,5-trisphosphate Biotin. Grade: >95%. Molecular formula: C25H42N4Na5O18P3S. Mole weight: 926.55. | |
| Insulin (cattle) | Insulin (cattle) is a polypeptide hormone that regulates glucose metabolism in pancreatic islet B cells. Synonyms: Insulin from bovine pancreas; Phe-Val-Asn-Gln-His-Leu-Cys-Gly-Ser-His-Leu-Val-Glu-Ala-Leu-Tyr-Leu-Val-Cys-Gly-Glu-Arg-Gly-Phe-Phe-Tyr-Thr-Pro-Lys-Ala. Gly-Ile-Val-Glu-Gln-Cys-Cys-Ala-Ser-Val-Cys-Ser-Leu-Tyr-Gln-Leu-Glu-Asn-Tyr-Cys-Asn (Disulfide bridge: Cys7-Cys7', Cys19-Cys20', Cys6'-Cys11'). Grade: ≥97%. CAS No. 11070-73-8. Molecular formula: C254H377N65O75S6. Mole weight: 5733.49. | |
| Insulin (human) | Two-chain polypeptide hormone produced by the β-cells of pancreatic islets. Its molecular weight is ~5800 Da. The α and β chains are joined by two interchain disulfide bonds. The α chain contains an intrachain disulfide bond. Insulin regulates the cellular uptake, utilization, and storage of glucose, amino acids, and fatty acids and inhibits the breakdown of glycogen, protein, and fat. Synonyms: Recombinant human insulin; Insulin human; H-Phe-Val-Asn-Gln-His-Leu-Cys(1)-Gly-Ser-His-Leu-Val-Glu-Ala-Leu-Tyr-Leu-Val-Cys(2)-Gly-Glu-Arg-Gly-Phe-Phe-Tyr-Thr-Pro-Lys-Thr-OH.H-Gly-Ile-Val-Glu-Gln-Cys(3)-Cys(1)-Thr-Ser-Ile-Cys(3)-Ser-Leu-Tyr-Gln-Leu-Glu-Asn-Tyr-Cys(2)-Asn-OH; L-phenylalanyl-L-valyl-L-asparagyl-L-glutaminyl-L-histidyl-L-leucyl-L-cysteinyl-glycyl-L-seryl-L-histidyl-L-leucyl-L-valyl-L-alpha-glutamyl-L-alanyl-L-leucyl-L-tyrosyl-L-leucyl-L-valyl-L-cysteinyl-glycyl-L-alpha-glutamyl-L-arginyl-glycyl-L-phenylalanyl-L-phenylalanyl-L-tyrosyl-L-threonyl-L-prolyl-L-lysyl-L-threonine (7->7'),(19->20')-bis(disulfide) compound with glycyl-L-isoleucyl-L-valyl-L-alpha-glutamyl-L-glutaminyl-L-cysteinyl-L-cysteinyl-L-threonyl-L-seryl-L-isoleucyl-L-cysteinyl-L-seryl-L-leucyl-L-tyrosyl-L-glutaminyl-L-leucyl-L-alpha-glutamyl-L-asparagyl-L-tyrosyl-L-cysteinyl-L-asparagine (6'->11')-disulfide. Grade: 95%. CAS No. 11061-68-0. Molecular formula: C257H383N65O77S6. Mole weight: 5807.57. | |
| Interleukin-1β Fragment 163-171 human | Interleukin-1β Fragment 163-171 human is a peptide involved in the regulation of immune responses, inflammatory reactions, and hematopoiesis. Synonyms: H-Val-Gln-Gly-Glu-Glu-Ser-Asn-Asp-Lys-OH; L-valyl-L-glutaminyl-glycyl-L-alpha-glutamyl-L-alpha-glutamyl-L-seryl-L-asparagyl-L-alpha-aspartyl-L-lysine; L-Lysine, L-valyl-L-glutaminylglycyl-L-α-glutamyl-L-α-glutamyl-L-seryl-L-asparaginyl-L-α-aspartyl-; L-Lysine, N2-[N-[N2-[N-[N-[N-[N-(N2-L-valyl-L-glutaminyl)glycyl]-L-α-glutamyl]-L-α-glutamyl]-L-seryl]-L-asparaginyl]-L-α-aspartyl]-; L-Valyl-L-glutaminylglycyl-L-α-glutamyl-L-α-glutamyl-L-seryl-L-asparaginyl-L-α-aspartyl-L-lysine; Sclavo peptide; β-Interleukin I (163-171), human. Grade: 95%. CAS No. 106021-96-9. Molecular formula: C39H64N12O19. Mole weight: 1004.99. | |
| Iodine (131 I) derlotuximab biotin | Iodine (131 I) derlotuximab biotin is a chimeric monoclonal antibody that targets DNA-histone H1 complex. Iodine (131 I) derlotuximab biotin is designed for the treatment of recurrent glioblastoma multiforme. Synonyms: Derlotuximab Biotin. Grade: 95%. CAS No. 340013-96-9. Molecular formula: C6436H9960N1704O2022S46. Mole weight: 145.0 kDa. | |
| Iodinin | Iodinin is an antibiotic produced by the strain of Chromobacterium iodinum etc. It has antibacterial and fungal properties. Synonyms: 5,6-dihydroxy-10-oxidophenazin-10-ium-1-one; 1,6-Phenazinediol 5,10-dioxide. CAS No. 68-81-5. Molecular formula: C12H8N2O4. Mole weight: 244.20. | |
| Iodoacetamido-PEG4-biotin | Iodoacetamido-PEG4-biotin is a biotin-PEG derivative for biotinylation. The biotin group serves as an affinity label towards the proteins avidin and streptavidin. Molecular formula: C22H39IN4O7S. Mole weight: 630.54. | |
| Iodoacetamido-PEG8-Biotin | Iodoacetamido-PEG8-Biotin is a biotin-PEG derivative for biotinylation. The biotin group serves as an affinity label towards the proteins avidin and streptavidin. Synonyms: IA-PEG8-Biotin. Molecular formula: C30H55IN4O11S. Mole weight: 806.75. | |
| Ionomycin | Ionomycin is a selective calcium ionophore antibiotic isolated from Streptomyces species. Anti-Gram-positive activity. Synonyms: 10,16-Docosadienoic acid, 11,19,21-trihydroxy-4,6,8,12,14,18,20-heptamethyl-22-[(2S,2'R,5S,5'S)-octahydro-5'-[(1R)-1-hydroxyethyl]-2,5'-dimethyl[2,2'-bifuran]-5-yl]-9-oxo-, (4R,6S,8S,10Z,12R,14R,16E,18R,19R,20S,21S)-; (4R,6S,8S,10Z,12R,14R,16E,18R,19R,20S,21S)-11,19,21-Trihydroxy-4,6,8,12,14,18,20-heptamethyl-22-[(2S,2'R,5S,5'S)-octahydro-5'-[(1R)-1-hydroxyethyl]-2,5'-dimethyl[2,2'-bifuran]-5-yl]-9-oxo-10,16-docosadienoic acid; 10,16-Docosadienoic acid, 11,19,21-trihydroxy-4,6,8,12,14,18,20-heptamethyl-22-[octahydro-5'-(1-hydroxyethyl)-2,5'-dimethyl[2,2'-bifuran]-5-yl]-9-oxo-, [2S-[2α[2'S*,5'R*(S*)],5β(4S*,6R*,8R*,10Z,12S*,14S*,16E,18S*,19S*,20R*,21R*)]]-; [2S-[2α[2'S*,5'R*(S*)],5β(4S*,6R*,8R*,10Z,12S*,14S*,16E,18S*,19S*,20R*,21R*)]]-11,19,21-Trihydroxy-4,6,8,12,14,18,20-heptamethyl-22-[octahydro-5'-(1-hydroxyethyl)-2,5'-dimethyl[2,2'-bifuran]-5-yl]-9-oxo-10,16-docosadienoic acid; SQ 23377; EM 94. Grade: >98% by HPLC. CAS No. 56092-81-0. Molecular formula: C41H72O9. Mole weight: 709.00. | |
| Ionomycin Calcium Salt | The Calcium Salt of Ionomycin, a kind of polyether antibiotic, is a selective calcium ionophore obtained from Streptomyces conglobatus by solvent extraction. It is more effective than A23187 as a calcium ionophore. It is used to study the transport of calcium ions on biological membranes. It can induce apoptotic degeneration of embryonic cortical neurons. Synonyms: Calcium ionophore; Calcium Ionomycin; (4R,6S,8S,10Z,12R,14R,16E,18R,19R,20S,21S)-11,19,21-Trihydroxy-4,6,8,12,14,18,20-heptamethyl-22-[(2S,2'R,5S,5'S)-octahydro-5'-[(1R)-1-hydroxyethyl]-2,5'-dimethyl[2,2'-bifuran]-5-yl]-9-oxo-10,16-Docosadienoic Acid Calcium Salt; 10,16-Docosadienoic acid, 11,19,21-trihydroxy-4,6,8,12,14,18,20-heptamethyl-22-[(2S,2'R,5S,5'S)-octahydro-5'-[(1R)-1-hydroxyethyl]-2,5'-dimethyl[2,2'-bifuran]-5-yl]-9-oxo-, calcium salt (1:1), (4R,6S,8S,10Z,12R,14R,16E,18R,19R,20S,21S)-; Ionomycin, calcium salt (1:1). Grade: ≥98%. CAS No. 56092-82-1. Molecular formula: C41H70O9Ca. Mole weight: 747.07. | |
| Irinotecan | Irinotecan is a topoisomerase I inhibitor for LoVo cells and HT-29 cells with IC50 of 15.8 μM and 5.17 μM, respectively. It is used for the treatment of colon and rectum cancers. It binds to topoisomerase I-DNA complex, preventing religation of the DNA strand and leading to double-strand DNA breakage and cell death. Uses: Anticancer drug. Synonyms: Irinophore C; Irinotecan lactone; Irinotecan mylan; Onivyde; 1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline, [1,4'-Bipiperidine]-1'-carboxylic Acid deriv.; (S)-[1,4'-Bipiperidine]-1'-carboxylic Acid 4,11-Diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl Ester; Camptosar; Irinotecanum; CPT-11; CPT 11; CPT11; (+)-Irinotecan. Grade: ≥98%. CAS No. 97682-44-5. Molecular formula: C33H38N4O6. Mole weight: 586.68. | |
| Irofulven | Irofulven is a semisynthetic sesquiterpene derivative of illudin S, a natural toxin isolated from the fungus Omphalotus illudens. Irofulven alkylates DNA and protein macromolecules, forms adducts, and arrests cells in the S-phase of the cell cycle. Synonyms: (6'R)-6'-Hydroxy-3'-(hydroxymethyl)-2',4',6'-trimethylspiro[cyclopropane-1,5'-[5H]inden]-7'(6'H)-one; (-)-(Hydroxymethyl)acylfulvene; (-)-Irofulven; HMAF; MGI 114; NSC 683863; 6-Hydroxymethylacylfulvene; Hydroxymethylacylfulvene; (R)-6'-Hydroxy-3'-(hydroxymethyl)-2',4',6'-trimethylspiro(cyclopropane-1,5'-(5H)inden)-7'(6'H)-one. Grade: ≥95%. CAS No. 158440-71-2. Molecular formula: C15H18O3. Mole weight: 246.12. | |
| Iromycin A | It is produced by the strain of Streptomyces sp. NK26588. Iromycin A is a bacterial pyridone metabolite that acts as a nitric oxide synthase (NOS) inhibitor with selectivity for NOS III (endothelial NOS) over NOS I (neuronal NOS). Synonyms: NK 26588; Antibiotic NK 26588; 2(1H)-Pyridinone, 6-[(2E,5E)-3,7-dimethyl-2,5-octadien-1-yl]-4-hydroxy-3-methyl-5-propyl-. Grade: ≥98%. CAS No. 213137-53-2. Molecular formula: C19H29NO2. Mole weight: 303.44. | |
| Isariin | Isariin is originally isolated from Isaria felina. Synonyms: (R)-N-(N-(N-(N-(N-(3-hydroxy-1-oxododecyl)glycyl)-L-valyl)-D-leucyl)-L-alanyl)-L-Valine rho-lactone; Cyclo[L-alanyl-L-valyl-(3R)-3-hydroxydodecanoylglycyl-L-valyl-D-leucyl]. CAS No. 10409-85-5. Molecular formula: C33H59N5O7. Mole weight: 637.85. | |
| Isocyclosporin A | A rearranged degradation product formed by acid treatment of cyclosporin A under aqueous and non-aqueous conditions. Synonyms: Ciclosporin Impurity C; O3.1,11-Anhydro[(2S,3R,4R,6E)-3-hydroxy-4-methyl-2-(methylamino)oct-6-enoyl-(2S)-2-aminobutanoyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valine]; Isociclosporin A; Cyclosporine EP Impurity C; Iso Cyclosporin A; Ciclosporin EP Impurity C; (2S,3R,4R,6E)-3-Hydroxy-4-methyl-2-(methylamino)-6-octenoyl-(2S)-2-aminobutanoyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valine (11→1)-Lactone; Iso Cyclosporine A; Cyclo[L-Abu-Sar-N-methyl-L-Leu-L-Val-N-methyl-L-Leu-L-Ala-D-Ala-N-methyl-L-Leu-N-methyl-L-Leu-N-methyl-L-Val-[(3R,4R)-3-hydroxy-N-methyl-5-[(E)-1-propenyl]-L-Leu-]]; [2S-(2R*,3S*,4S*,6E)]-N-[3-Hydroxy-4-methyl-2-(methylamino)-1-oxo-6-octenyl]-L-α-aminobutyryl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valine θ1-lactone. Grade: ≥90% by HPLC. CAS No. 59865-16-6. Molecular formula: C62H111N11O12. Mole weight: 1202.61. | |
| Iso Cyclosporin H Trifluoroacetic Acid Salt | Iso Cyclosporin H Trifluoroacetic Acid Salt is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Synonyms: (2S,3R,4R,6E)-3-Hydroxy-4-methyl-2-(methylamino)-6-octenoyl-(2S)-2-aminobutanoyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-D-valine (11→1)-Lactone Trifluoroacetic Acid Salt; 10-(N-Methyl-D-valine)isocyclosporin A Trifluoroacetic Acid Salt; Cyclosporine Impurity 19 Trifluoroacetic Acid Salt; D-Valine, (2S,3R,4R,6E)-3-hydroxy-4-methyl-2-(methylamino)-6-octenoyl-(2S)-2-aminobutanoyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-, (11→1)-lactone, Trifluoroacetic Acid Salt; Isocyclosporin H Trifluoroacetic Acid Salt. Grade: ≥90% by HPLC. Molecular formula: C62H111N11O12.C2HF3O2. Mole weight: 1316.63. | |
| Isonipecotic acid | Isonipecotic acid is a GABAA receptor partial agonist. Synonyms: 4-Piperidinecarboxylic acid; 4-Carboxypiperidine; Hexahydroisonicotinic acid; 4-Hexahydroisonicotinic acid; NSC 61049; H-Inp-OH; Isonipecotinic Acid. Grade: ≥95%. CAS No. 498-94-2. Molecular formula: C6H11NO2. Mole weight: 129.16. | |
| Isopropyl-β-D-thiogalactopyranoside | IPTG is a galactose analog that is used in combination with X-GAL in cloning procedures requiring expression of β-galactosidase activity. Synonyms: IPTG; Isopropyl-beta-D-thiogalactopyranoside; Isopropyl β-D-thiogalactoside (IPTG); Isopropyl β-D-1-thiogalactopyranoside; Isopropyl 1-thio-b-D-galactopyranoside; Isopropyl 1-Thio-β-D-galactopyranoside; Isopropyl β-D-thiogalactoside; 1-Methylethyl 1-thio-beta-D-galactopyranoside. Grade: ≥98% by HPLC. CAS No. 367-93-1. Molecular formula: C9H18O5S. Mole weight: 238.30. | |
| Isotocin | Isotocin is a peptide hormone particularly used in the research of psychiatric afflictions, drug addiction and post-traumatic stress disorder. Synonyms: (Ser4,Ile8)-Oxytocin; H-Cys-Tyr-Ile-Ser-Asn-Cys-Pro-Ile-Gly-NH2 (Disulfide bridge: Cys1-Cys6); L-cysteinyl-L-tyrosyl-L-isoleucyl-L-seryl-L-asparagyl-L-cysteinyl-L-prolyl-L-isoleucyl-glycinamide (1->6)-disulfide; [4-Serine,8-Isoleucine]Oxytocin; 4-L-serine-8-L-isoleucineoxytocin; (2S)-1-[(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxo-ethyl)-10-(hydroxymethyl)-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-13-sec-butyl-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]-N-[(1S,2S)-1-[(2-amino-2-oxo-ethyl)carbamoyl]-2-methyl-butyl]pyrrolidine-2-carboxamide. Grade: ≥95%. CAS No. 550-21-0. Molecular formula: C41H63N11O12S2. Mole weight: 966.14. | |
| ISRIB | ISRIB is a symmetric bis-glycolamide that inhibits integrated stress response (ISR). In wild-type mice studies has shown that it improved memory by efficiently reversing the effects of eIF2α phosphorylation, which has brought expectation that inhibition of PERK signaling may have the potential to ameliorate Alzheimer's disease. In a present study ISRIB demonstrated to attenuate amyloid b-induced neuronal cell death although the pharmacological mechanisms of this action have not yet been elucidated. Synonyms: 2-(4-chlorophenoxy)-N-[4-[[2-(4-chlorophenoxy)acetyl]amino]cyclohexyl]acetamide; 2-(4-chlorophenoxy)-N-(4-(2-(4-chlorophenoxy)acetamido)cyclohexyl)acetamide; ISRIB compound; trans-ISRIB. CAS No. 1597403-47-8. Molecular formula: C22H24Cl2N2O4. Mole weight: 451.34. | |
| ISRIB (mix-Isomer) | ISRIB (mix-Isomer), is a symmetric bis-glycolamide that inhibits integrated stress response (ISR). In wild-type mice studies has shown that it improved memory by efficiently reversing the effects of eIF2α phosphorylation, which has brought expectation that inhibition of PERK signaling may have the potential to ameliorate Alzheimer's disease. In a present study ISRIB demonstrated to attenuate amyloid b-induced neuronal cell death although the pharmacological mechanisms of this action have not yet been elucidated. Synonyms: Acetamide, N,?N'-1,?4-cyclohexanediylbis[2?-(4-chlorophenoxy)?- ISRIB compound. CAS No. 548470-11-7. Molecular formula: C22H24Cl2N2O4. Mole weight: 451.34. | |
| IT-143-B | IT-143-B is produced by the strain of Streptomyces sp.IT-143. It has activity against individual gram-positive bacteria (Micrococcus gaminerae) and individual fungi (Aspergillus fumigatus). And it is also cytotoxic to KB cells. Synonyms: IT-143B. Grade: ≥95%. CAS No. 183485-34-9. Molecular formula: C28H41NO4. Mole weight: 455.63. | |
| Ivermectin | Ivermectin is a glutamate-gated chloride channel (GluCls) activator, which is used as an antiparasitic drug for the treatment of certain parasitic roundworm infections. Ivermectin inhibits the chloride channels of helminthic parasites and has been shown to have clinical efficacy for the treatment of onchocerciasis, strongyloidiasis, and ectoparasitic infection. Ivermectin is a mixture of mostly Ivermectin B1a (>80%) with some Ivermectin B1b (<20%), which are macrolides from Streptomyces avermitilis. Uses: Antiparasitic agents. Synonyms: Ivermectin B1a and Ivermectin B1b (Mixture); Avermectin H2B1a and Avermectin H2B1b (Mixture); Dihydroavermectin B1a and Dihydroavermectin B1b (Mixture); 22,23-Dihydroavermectin B1a and 22,23-Dihydroavermectin B1b (Mixture). Grade: ≥95%. CAS No. 70288-86-7. Molecular formula: C48H74O14.C47H72O14. Mole weight: 1736.16. | |
| Ivermectin B1a | It is the major component (>80%) of the commercial anthelmintic, ivermectin. It exerts its anthelmintic effects by binding to glutamate-gated chloride channels expressed on nematode neurones and pharyngeal muscle cells. It is also a potent insecticide. Synonyms: Ivermectin; Dihydroavermectin B1a; 22,23-Dihydroavermectin B1a; Ivermectin Component B1a; avermectin H2B1a; 5-O-demethyl-22,23-dihydroavermectin A1a; MK-933; Avermectin A1a, 5-O-demethyl-22,23-dihydro-; 22,23-Dihydroavermectin B(1)a; Spiro[11,15-methano-2H,13H,17H-furo[4,3,2-pq][2,6]benzodioxacyclooctadecin-13,2'-[2H]pyran], avermectin A1a deriv.; Ivermectin (IVM); IVM; dihydro avermectin Bla; H2B1a; Ivermectin (MK-0933). Grade: >95% by HPLC. CAS No. 71827-03-7. Molecular formula: C48H74O14. Mole weight: 875.09. | |
| Ivermectin B1a-[d2] | Ivermectin B1a-[d2] is the labelled analogue of Ivermectin B1a, which is a major component of ivermectin and a semi-synthetic derivative of abamectin. It is a mixture including not less than 80% component B1a and not more than 20% component B1b. It is used as an antihelmintic. Synonyms: Ivermectin B1a-d2; 5-O-Demethyl-22,23-dihydro-avermectin A1a-d2; 2,23-Dihydroavermectin B1a-d2; Dihydroavermectin B1a-d2. Grade: ≥94%; ≥95% atom D. Molecular formula: C48H72D2O14. Mole weight: 877.11. | |
| Ivermectin B1 aglycone | A semi-synthetic product produced by hydrolysing the disaccharide unit of ivermectin. It is a potent inhibitor of nematode larval development, but is devoid of paralytic activity. The aglycone is used as a sensitive probe for the detection of some types of ivermectin resistance. An impurity of Ivermectin. Synonyms: Dihydroavermectin B1 aglycone; (6R,13S,25R)-5-O-Demethyl-28-deoxy-6,28-epoxy-13-hydroxy-25-[(1S)-1-methylpropyl]-milbemycin B; [6R,13S,25R(S)]-5-O-Demethyl-28-deoxy-6,28-epoxy-13-hydroxy-25-(1-methylpropyl)-milbemycin B; 22,23-Dihydroavermectin B1a Aglycon; Ivermectin Aglycone; 13-O-De[4-O-(2,6-dideoxy-3-O-methyl-α-L-glucopyranosyl)-2,6-dideoxy-3-O-methyl-α-L-glucopyranosyl]-22,23-dihydro-27-noravermectin A1. Grade: >99% by HPLC. CAS No. 123997-59-1. Molecular formula: C34H50O8. Mole weight: 586.76. | |
| Ivermectin B1b | Ivermectin B1b is a minor component of Ivermectin, a semi-synthetic derivative of Abamectin. Ivermectin is a medication that is effective against many types of parasites. Synonyms: Ivermectin B1b; Avermectin H2B1b; Ivermectin Component B1b; dihydroavermectin B1b; 70209-81-3; 22,23-dihydroavermectin B1b; 0W28CYI3TU; CHEBI:63943; Avermectin A1a, 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)-; (1R,4S,5'S,6R,6'R,8R,10E,12S,13S,14E,16E,20R,21R,24S)-21,24-dihydroxy-12-[(2R,4S,5S,6S)-5-[(2S,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-5',11,13,22-tetramethyl-6'-propan-2-ylspiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-2-one; UNII-0W28CYI3TU; Stromectol (TN); Soolantra (TN); EINECS 274-384-5; Sklice (TN); H2B1b; CHEMBL552; Ivermectin (JAN/USP/INN); SCHEMBL313003; DTXSID3023182; VARHUCVRRNANBD-PVVXTEPVSA-N; IVERMECTIN COMPONENT B1B [MI]; HY-125729; CS-0093431; NS00093438; D00804; Q27132925; 5-O-DEMETHYL-25-DE(1-METHYLPROPYL)-22,23-DIHYDRO-25-(1-METHYLETHYL)AVERMECTIN A1A; Avermectin A(sub 1a), 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)-. Grade: >95% by HPLC. CAS No. 70209-81-3. Molecular formula: C20H38N6O4. Mole weight: 426.6. | |
| Ivermectin-d2 | An isotope labelled Ivermectin. Ivermectin is a medication used to treat certain parasitic roundworm infections. Synonyms: 22,23-Dihydroavermectin B1-d2; 22,23-Dihydro C-076B1-d2. Grade: > 95%. Molecular formula: C48H72O14D2. Mole weight: 877.13. | |
| Ivermectin-[d2] | Ivermectin-[d2] is the labelled analogue of Ivermectin, which is a semi-synthetic derivative of Abamectin consisting of a mixture of not less than 80% component B1a and not more than 20% component B1b. Antihelmintic (Onchocerca). An in vitro inhibitor of SARS-CoV-2/Covid-19. Synonyms: 22,23-Dihydroavermectin B1-d2; 22,23-Dihydro C-076B1-d2; Heartgard 30; Ivomec-d2; Ivosint-d2; Mectizan-d2; Stromectol-d2; Uvemec-d2; Vermic-d2; Zimecterin-d2. Grade: 98% by CP; 97% atom D. Molecular formula: C48H72D2O14. Mole weight: 877.11. | |
| Ivermectin EP Impurity D | Ivermectin EP Impurity D is an impurity of Ivermectin, an antiparasitic drug that is active against a wide variety of nematode and arthropod parasites and is used to treat scabies and lice in humans. Synonyms: 5-O-demethyl-28-oxo-22,23-dihydroavermectin A1a; 28-oxoH2B1a; 28-Oxo Ivermectin B1a (Impurity); 5-O-Demethyl-22,23-dihydro-28-oxo-avermectin A1a; Spiro[11,15-methano-2H,13H,17H-furo[4,3,2-pq][2,6]benzodioxacyclooctadecin-13,2'-[2H]pyran] Avermectin A1a Deriv. Grade: > 95%. CAS No. 102190-55-6. Molecular formula: C48H72O15. Mole weight: 889.10. | |
| Ivermectin EP Impurity E | Ivermectin EP Impurity E is an impurity of Ivermectin, an antiparasitic drug that is active against a wide variety of nematode and arthropod parasites and is used to treat scabies and lice in humans. Synonyms: 5-O,12-didemethyl-12-ethyl-22,23-dihydroavermectin A1a; 12-demethyl-12-ethyl-H2B1a. Molecular formula: C49H76O14. Mole weight: 889.13. | |
| Ivermectin EP Impurity F | Ivermectin EP Impurity F is an impurity of Ivermectin, an antiparasitic drug that is active against a wide variety of nematode and arthropod parasites and is used to treat scabies and lice in humans. Synonyms: 5-O,12-didemethyl-25-de(1-methylpropyl)-12-ethyl-25-(1-methylethyl)-22,23-dihydroavermectin A1a; 12-demethyl-12-ethyl-H2B1b. Molecular formula: C48H74O14. Mole weight: 875.11. | |
| Ivermectin EP Impurity G | Ivermectin EP Impurity G is an impurity of Ivermectin, an antiparasitic drug that is active against a wide variety of nematode and arthropod parasites and is used to treat scabies and lice in humans. Synonyms: Ivermectin B1 Aglycon; (6R,13S,25R)-5-O-Demethyl-28-deoxy-6,28-epoxy-13-hydroxy-25-[(1S)-1-methylpropyl]-milbemycin B; [6R,13S,25R(S)]-5-O-Demethyl-28-deoxy-6,28-epoxy-13-hydroxy-25-(1-methylpropyl)-milbemycin B; H2B1a aglycone. Grade: > 95%. CAS No. 73162-95-5. Molecular formula: C34H50O8. Mole weight: 586.77. | |
| Ivermectin EP Impurity H | Ivermectin EP Impurity H is an impurity of Ivermectin, an antiparasitic drug that is active against a wide variety of nematode and arthropod parasites and is used to treat scabies and lice in humans. Synonyms: Ivermectin B1 Mono-sugar Derivative; 4'-O-De(2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl)-5-O-demethyl-22,23-dihydro-avermectin A1a; Spiro[11,15-methano-2H,13H,17H-furo[4,3,2-pq][2,6]benzodioxacyclooctadecin-13,2'-[2H]pyran] Avermectin A1a Deriv. Grade: >95%. CAS No. 71837-27-9. Molecular formula: C41H62O11. Mole weight: 730.94. | |
| Ivermectin EP Impurity J | Ivermectin EP Impurity J is an impurity of Ivermectin, an antiparasitic drug that is active against a wide variety of nematode and arthropod parasites and is used to treat scabies and lice in humans. Synonyms: 2,3-didehydro-5-O-demethyl-25-de(1-methylpropyl)-25-(1-methylethyl)-3,4,22,23-tetrahydroavermectin A1a; Δ2,3H2B1b. Molecular formula: C47H72O14. Mole weight: 861.08. | |
| Ivermectin EP Impurity K | Ivermectin EP Impurity K is an impurity of Ivermectin, an antiparasitic drug that is active against a wide variety of nematode and arthropod parasites and is used to treat scabies and lice in humans. Synonyms: 3,4-Dihydro Ivermectin (Mixture of Diastereomers) ; 5-O-Demethyl-3,4,22,23-tetrahydro-avermectin A1a; Spiro[11,15-methano-2H,13H,17H-furo[4,3,2-pq][2,6]benzodioxacyclooctadecin-13,2'-[2H]pyran] Avermectin A1a Deriv. Grade: > 95%. CAS No. 74567-01-4. Molecular formula: C48H76O14. Mole weight: 877.13. | |
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