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APF Sialoglycopeptide ammonium salt
APF Sialoglycopeptide ammonium salt is a cutting-edge biomedical compound, demonstrating remarkable capabilities in research of dental caries. Proven to possess potent antimicrobial properties against the notorious Streptococcus mutans, this compound also exhibits an extraordinary affinity for hydroxyapatite, amplifying the process of tooth remineralization. Synonyms: O-(Acetamido-3,5-dideoxy-D-glycero-a-D-galacto-2-nonulopyranosylonic acid)-(2?3)-O-b-D- galactopyranosyl-(1?3)-O-a-2-acetamido-2-deoxy-D-galactopyranosyl-(1 ?O)- Thr-Val-Pro-Ala-Ala-Val-Val-Val-Ala NeuNAc-a(2?3)-Gal-b(1?3)-GalNAc-a-Thr-Val-Pro-Ala-Ala-Val-Val-Val-Ala. Molecular formula: C63H107N11O29. Mole weight: 1482.58.
ApG
ApG is a scientifically advanced compound, specifically designed to study inflammatory skin disorders as well as combat skin infections. It comprises a potent blend of bioactive drugs exhibiting exceptional antimicrobial and anti-inflammatory attributes. Grades: ≥ 95% by HPLC. Molecular formula: C20H25N10O11P (free acid). Mole weight: 612.14 (free acid).
APHE-2
APHE-2 is a pyrazoloisoquinolinone antibiotic produced by Streptoverticillium griseocarneum. It has weak anti-Gram-positive bacteria activity. Synonyms: 1H-Indole, 3-(2-propyl-5-oxazolyl)-; WS-30581A. CAS No. 93773-64-9. Molecular formula: C14H14N2O. Mole weight: 226.27.
APHE-3
APHE-3 is a pyrazoloisoquinolinone antibiotic produced by Streptoverticillium griseocarneum. It has weak anti-Gram-positive bacteria activity. APHE-3 can also inhibit lymphocyte proliferation in the presence of Phytohemagglutinin, with IC50 of about 0.1 mmol/L. Synonyms: Pimprinine; WS 30581C. Grades: >95% by HPLC. CAS No. 13640-26-1. Molecular formula: C12H10N2O. Mole weight: 198.22.
APHE-4
APHE-4 is a pyrazoloisoquinolinone antibiotic produced by Streptoverticillium griseocarneum. It has weak anti-Gram-positive bacteria activity. Synonyms: WS 30581B. CAS No. 93773-63-8. Molecular formula: C15H16N2O. Mole weight: 240.30.
Aphidicolin-17-monoacetate
Aphidicolin-17-monoacetate is an antibiotic produced by Phoma betae PS-13, which inhibits DNA polymerase and interferes with root growth. Molecular formula: C22H36O5. Mole weight: 380.52.
Aphidicolin-3,18-orthoacetate
Aphidicolin-3,18-orthoacetate is an antibiotic produced by Phoma betae. It is a kind of phytotoxin, which can inhibit the growth of the roots of rice and mango. Molecular formula: C22H36O5. Mole weight: 380.52.
Aphthosin
Aphthosin is a tetrapeptide glycoside isolated from Peltigera aphthosa (L.) Willd. Synonyms: 2,6-Cresotic acid, 4-methoxy-, 4-ester with 6-methyl-β-resorcylic acid, 4-ester with 6-methyl-β-resorcylic acid, 4-ester with methyl 6-methyl-β-resorcylate (8CI). CAS No. 31449-13-5. Molecular formula: C34H30O13. Mole weight: 646.59.
Apicularen A
Apicularen A is a macrolide antibiotic produced by Chondromyces robustus Cma 13. Apicularen A has no antibacterial activity, but for human and animal tumor cells such as KB-3-1, KB-V1, K-562, HL-60, U-937, A-498, A-549, PC-3 and SK-OV -3 grade has strong cytotoxicity. CAS No. 220757-04-0. Molecular formula: C25H31NO6. Mole weight: 441.52.
Apicularen B
Apicularen B is a macrolide antibiotic produced by Chondromyces robustus Cma 13. Apicularen B has low cytotoxicity and weak anti-Gram-positive bacteria activity. CAS No. 220757-06-2. Molecular formula: C33H44N2O11. Mole weight: 644.71.
Apigenin
Apigenin is the main active ingredient of Chamomil Extract. Chamomile is rich in flavonoid active ingredients, which has antioxidant, anti-angiogenic, anti-inflammatory, anti-allergic and anti-viral effects. The active ingredients of chamomile can be applied to high-end anti-sensitive skin care products through issofree technology. It has a good soothing effect on itchy skin, it gently replenishes water and soothes the skin. Apigenin is a potent P450 inhibitor for CYP2C9 with Ki of 2 μM. Apigenin is a good functional cosmetics material. Synonyms: NSC 83244; NSC83244; NSC-83244; LY 080400; LY080400; LY-080400; 5,7-Dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one; Chamomile; Spigenin; Versulin; Chamomil Extract. Grades: 5%-98%; 10:1. CAS No. 520-36-5. Molecular formula: C15H10O5. Mole weight: 270.24.
Apigenin 4'-β-D-Gucopyranoside Triacetate Methyl Ester is an intermediate in synthesizing Isorhoifolin, a naturally occurring flavonoid that was shown to exhibit potential antidiabetic, antihyperlipidemic and antioxidant effects. Synonyms: (2S,3R,4S,5S,6S)-2-(4-(5,7-Dihydroxy-4-oxochroman-2-yl)phenoxy)-6-(methoxycarbonyl)tetrahydro-2H-pyran-3,4,5-triyl Triacetate. Molecular formula: C28H28O14. Mole weight: 588.51.
Apigenin 5-O-neohesperidoside
Apigenin 5-O-neohesperidoside is a natural flavonoid compound found in several plants. Synonyms: 5-[[2-O-(6-Deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl]oxy]-7-hydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one. Grades: >95%. CAS No. 850630-40-9. Molecular formula: C27H30O14. Mole weight: 578.52.
A compound of the flavonoid class found in the Viola yedoensis. Synonyms: 6-C-alpha-L-Arabinopyranosyl-8-C-beta-D-xylopyranosylapigenin. Grades: >98%. CAS No. 677021-30-6. Molecular formula: C25H26O13. Mole weight: 534.47.
Apigenin 7-β-D-Gucopyranoside Triacetate Methyl Ester is an intermediate in synthesizing Isorhoifolin, a naturally occurring flavonoid that was shown to exhibit potential antidiabetic, antihyperlipidemic and antioxidant effects. Synonyms: (2S,3R,4S,5S,6S)-2-((5-Hydroxy-2-(4-hydroxyphenyl)-4-oxochroman-7-yl)oxy)-6-(methoxycarbonyl)tetrahydro-2H-pyran-3,4,5-triyl Triacetate. Molecular formula: C28H28O14. Mole weight: 588.51.
Apigenin 7-O-(2G-rhamnosyl)gentiobioside
Apigenin 7-O-(2G-rhamnosyl)gentiobioside, a flavonoid compound ubiquitously present in a multitude of plants, specifically in parsley, celery, and chamomile, has been established to hold an impressive armory of antioxidant, anti-inflammatory, and anti-cancer activities. Its therapeutic potential in treating several diseases, including cardiovascular diseases, neurodegenerative diseases, and diabetes, has been suggested by extensive research studies. Moreover, it has been observed to manifest antiviral properties against a diverse pool of viruses, such as HIV-1. Synonyms: Apigenin-7-O-(2G-rhamnosyl)gentiobioside. Grades: >98%. CAS No. 174284-20-9. Molecular formula: C33H40O19. Mole weight: 740.7.
apigenin-7-O-glucronide
Apigenin-7-glucuronide inhibited the major pathways of arachidonate metabolism in leukocytes. Synonyms: 5-hydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-7-yl beta-D-glucopyranosiduronic acid. Grades: >98%. CAS No. 29741-09-1. Molecular formula: C21H18O11. Mole weight: 446.4.
Apigenin 7-O-malonylglucoside
Apigenin 7-O-malonylglucoside is a flavonoid isolated from Chamomilla recutita. Synonyms: Apigenin 7-O-malonylglucoside; AOF5Z3UWMW; Apigenin 7-O-(6''-O-malonylglucoside); Apigenin 7-O-(6-malonyl-beta-D-glucoside); C10020; Apigenin 7-(6''-malonylglucoside); Apigenin 7-O-(6-O-malonylglucoside); 3-oxo-3-[[(2R,3S,4S,5R,6S)-3,4,5-trihydroxy-6-[5-hydroxy-2-(4-hydroxyphenyl)-4-oxochromen-7-yl]oxyoxan-2-yl]methoxy]propanoic acid; Apigenin 7-O-(6 inverted exclamation mark -O-malonyl)-|A-D-glucoside. Grades: 0.98. CAS No. 86546-87-4. Molecular formula: C24H22O13. Mole weight: 518.42.
Apigenin-8-C-glucoside
Cas No. 64820-99-1.
Apiin
Apiin is a flavonoid compound extracted from parsley which shows inhibition towards viral neuramindase. It also shows antiproliferative and apoptotic effects towards human cancer cells. Uses: Antiproliferative/apoptotic. Synonyms: Apigenin-7-(2-O-apiosylglucoside) 7-[2-O-(Apio-b-D-furanosy)l-b-D-glucopyranosyl)oxy]-5-hydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one. Grades: >98%. CAS No. 26544-34-3. Molecular formula: C26H28O14. Mole weight: 564.50.
Apilimod
Apilimod is a potent and orally bioavailable inhibitor of the cytokines interleukin-12 (IL-12) and interleukin-23 (IL-23) with the potential to treat certain autoimmune and inflammatory diseases by inhibition of IL-12 and IL-23 production. Synonyms: STA-5326; STA 5326;STA5326; N-[(E)-(3-methylphenyl)methylideneamino]-6-morpholin-4-yl-2-(2-pyridin-2-ylethoxy)pyrimidin-4-amine. Grades: 99%. CAS No. 541550-19-0. Molecular formula: C23H26N6O2. Mole weight: 418.49.
Apilimod mesylate
The mesylate salt form of Apilimod. Apilimod is a potent and orally-available inhibitor of the cytokines interleukin-12 (IL-12) and interleukin-23 (IL-23) with the potential to treat certain autoimmune and inflammatory diseases by inhibition of IL-12 and IL-23 production. Synonyms: methanesulfonic acid N-[(E)-(3-methylphenyl)methylideneamino]-6-morpholin-4-yl-2-(2-pyridin-2-ylethoxy)pyrimidin-4-amine. Grades: 98%. CAS No. 870087-36-8. Molecular formula: C23H26N6O2.2CH4O3S. Mole weight: 610.7.
Apimostinel
Apimostinel is a selective partial agonist of an allosteric site of the glycine site of the NMDA receptor complex under investigation by Naurex. Its mechanism of action and effects are similar to those of rapastinel. But Apimostinel is 100-fold more potent by weight and, unlike rapastinel (which must be administered via intravenous injection), is orally-active. Phase II clinical trials for the treatment of Major depressive disorder is on-going. Uses: Major depressive disorder. Synonyms: NRX-1074; NRX 1074; NRX1074; AGN-241660; AGN241660; AGN 241660. Apimostinel;(2R)-1-[(2S)-1-[(2S,3R)-2-amino-3-hydroxybutanoyl]pyrrolidine-2-carbonyl]-N-[(2S,3R)-1-amino-3-hydroxy-1-oxobutan-2-yl]-2-benzylpyrrolidine-2-carboxamide. Grades: 98%. CAS No. 1421866-48-9. Molecular formula: C25H37N5O6. Mole weight: 503.60.
Apiogalacturonan
Apiogalacturonan, depicted as a remarkable bioactive polysaccharide deeply rooted in the plant kingdom, showcasing immense promise application in studying diverse ailments such as malignancies, diabetes and cardiovascular afflictions. Synonyms: Galacturonoapian. CAS No. 9039-3-6.
Apiosylskimmin
Apiosylskimmin is a natural product from plants. Synonyms: 2H-1-Benzopyran-2-one,7-[(6-O-D-apio-b-D-furanosyl-b-D-glucopyranosyl)oxy]-; MLS002473238; CHEMBL1719219; MolPort-006-668-333; 7-[(2S,3R,4S,5S,6R)-6-[[(2R,3R,4R)-3,4-dihydroxy-4-(hydroxymethyl)oxolan-2-yl]oxymethyl]-3,4,5-trihydroxyoxan-2-yl]oxychromen-2-one. CAS No. 103529-94-8. Molecular formula: C20H24O12. Mole weight: 456.41.
Apitolisib
Apitolisib, also known as GDC-0980 and RG7422; or GNE390, is a dual PI3 kinase/mTOR inhibitor, is also an orally available agent targeting phosphatidylinositol 3 kinase (PI3K) and mammalian target of rapamycin (mTOR) kinase in the PI3K/mTOR signaling pathway, with potential antineoplastic activity. PI3K/mTOR kinase inhibitor GDC-0980 inhibits both PI3K kinase and mTOR kinase, which may result in tumor cell apoptosis and growth inhibition of cancer cells overexpressing PI3K/mTOR. Activation of the PI3K/mTOR pathway promotes cell growth, survival, and resistance to chemotherapy and radiotherapy; mTOR, a serine/threonine kinase downstream of PI3K, may also be activated in a PI3K-independent fashion. Synonyms: GDC-0980; GDC0980; GDC 0980; RG7422; RG-7422; RG 7422; GNE 390; GNE390; GNE-390; Apitolisib. CAS No. 1032754-93-0. Molecular formula: C23H30N8O3S. Mole weight: 498.606.
Apixaban
Apixaban (INN, trade name Eliquis) is an anticoagulant for the prevention of venous thromboembolism and the prevention of stroke in atrial fibrillation. It is a direct factor Xa inhibitor. Apixaban has been available in Europe since May 2011. The drug was developed in a joint venture by Pfizer and Bristol-Myers Squibb. Uses: Factor xa inhibitors. Synonyms: BMS-562247-01; BMS 562247-01; BMS562247-01; brand name: Eliquis. Grades: 0.98. CAS No. 503612-47-3. Molecular formula: C25H25N5O4. Mole weight: 459.506.
Apixaban Acid
A metabolite of Apixaban, a direct factor Xa inhibitor used as an anticoagulant for the prevention of venous thromboembolism and stroke in atrial fibrillation. Synonyms: 1-(4-Methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid; Apixaban Impurity 41. CAS No. 503614-92-4. Molecular formula: C25H24N4O5. Mole weight: 460.5.
Apixaban Dehydro Impurity
A metabolite of Apixaban, a direct factor Xa inhibitor used as an anticoagulant for the prevention of venous thromboembolism and stroke in atrial fibrillation. Synonyms: 4,5-Dehydro Apixaban; 1-(4-Methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-6,7-dihydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide; 6,7-Dihydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl)phenyl]-1H-Pyrazolo[3,4-c]pyridine-3-carboxamide. Grades: > 95%. CAS No. 1074549-89-5. Molecular formula: C25H23N5O4. Mole weight: 457.49.
Apixaban Impurity 14
A metabolite of Apixaban. Synonyms: 6-(4-Aminophenyl)-4,5,6,7-tetrahydro-1-(4-methoxyphenyl)-7-oxo-1H-pyrazolo[3,4-c]pyridine-3-carboxylic Acid. Grades: > 95%. CAS No. 1704504-93-7. Molecular formula: C20H18N4O4. Mole weight: 378.39.
Apixaban Impurity 15
A metabolite of Apixaban. Synonyms: 6-(4-Aminophenyl)-4,5,6,7-tetrahydro-1-(4-methoxyphenyl)-7-oxo-1H-pyrazolo[3,4-c]pyridine-3-carboxylic Acid Methyl Ester. Grades: > 95%. CAS No. 1466571-07-2. Molecular formula: C21H20N4O4. Mole weight: 392.42.
Apixaban Impurity 6
A metabolite of Apixaban, a direct factor Xa inhibitor used as an anticoagulant for the prevention of venous thromboembolism and stroke in atrial fibrillation. Synonyms: Apixaban Acid Methyl Ester. Grades: > 95%. CAS No. 1074365-84-6. Molecular formula: C26H26N4O5. Mole weight: 474.52.
Apixaban Impurity 9
A metabolite of Apixaban. Synonyms: Apixaban V; 1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic Acid Ethyl Ester Ethyl 1-(4-Methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyri. Grades: > 95%. CAS No. 503614-91-3. Molecular formula: C27H28N4O5. Mole weight: 488.55.
Apixaban Related Compound 1
A metabolite of Apixaban. Synonyms: Ethyl (2E)-2-[(4-methoxyphenyl)hydrazono]propanoate. Grades: > 95%. CAS No. 4792-57-8. Molecular formula: C12H16N2O3. Mole weight: 236.27.
Apixaban Related Compound 2
A metabolite of Apixaban. Synonyms: 3-chloro-1-(4-methoxyphenyl)-5,6-dihydropyridin-2(1H)-one. Grades: > 95%. CAS No. 536760-29-9. Molecular formula: C11H9ClN2O3. Mole weight: 252.66.
Apixaban Related Compound 3
A metabolite of Apixaban. Synonyms: 5-chloro-4-methylpentanoyl chloride. Grades: > 95%. CAS No. 813452-05-0. Molecular formula: C6H10Cl2O. Mole weight: 169.05.
Apixaban Related Compound 4
A metabolite of Apixaban. Synonyms: 5-Chloro-hexanoyl Chloride. Grades: > 95%. CAS No. 99585-01-0. Molecular formula: C6H10Cl2O. Mole weight: 169.05.
Aplasmomycin
Aplasmomycin A is an antibiotic with antimalarial activity isolated from Streptomycete. Aplasmomycin has the activity of inhibiting gram-positive bacteria and mycobacteria, and has anti-protozoal effects. Synonyms: Aplasmomycin A. CAS No. 61230-25-9. Molecular formula: C40H60BNaO14. Mole weight: 798.69.
Aplasmomycin B
Aplasmomycin B is an antibiotic with antimalarial activity isolated from Streptomycete. Aplasmomycin has the activity of inhibiting gram-positive bacteria and mycobacteria, and has anti-protozoal effects. CAS No. 68193-20-4. Molecular formula: C42H62BNaO15. Mole weight: 840.73.
Aplasmomycin C
Aplasmomycin C is an antibiotic with antimalarial activity isolated from Streptomycete. Aplasmomycin has the activity of inhibiting gram-positive bacteria and mycobacteria, and has anti-protozoal effects. CAS No. 68193-21-5. Molecular formula: C44H64BNaO16. Mole weight: 882.77.
Apl-AvBD16
Apl-AvBD16 is isolated from Peking duck, Anas platyrhynchos. It has antibacterial and antiviral activity.
ApNHp
ApNHpp
ApNHpp is a biomedical compound hindering adenosine 5'-monophosphate-activated protein kinase (AMPK), a key orchestrator in the intricate symphony of energy equilibrium and metabolism. Synonyms: (AMPNPP); Adenosine-5'-[(α,β)-imido]triphosphate, Sodium salt. Grades: ≥ 95% by HPLC. CAS No. 114635-42-6. Molecular formula: C10H17N6O12P3 (free acid). Mole weight: 506.20 (free acid).
APO-10
APO-10 is a novel non-ionic detergent useful for plasmid DNA isolation. Synonyms: Decyl(Dimethyl)phosphine Oxide; Dimethyldecylphosphine oxide. Grades: 95%. CAS No. 2190-95-6. Molecular formula: C12H27OP. Mole weight: 218.32.
Apoatropine
Apoatropine is an alkaloid derivative with the potential to be an antibacterial. Synonyms: 1-alpha-H,5-alpha-H-Tropan-3-alpha-ol, atropate; 8-Methyl-8-azabicyclo[3.2.1]oct-3-yl atropate; alpha-methylene-benzeneaceticaci8-methyl-8-azabicyclo(3.2.1)oct-3-yles. Grades: > 95%. CAS No. 500-55-0. Molecular formula: C17H21NO2. Mole weight: 271.36.
Apo-Enopeptin methyl ester
Apo-enopeptin methyl ester is a derivative of enopeptin A. Grades: >95% by HPLC. Molecular formula: C48H61N7O12. Mole weight: 928.03.
apo-Enterobactin
apo-Enterobactin is a derivative of enterobactin (enterochelin). Synonyms: Enterobactin, apo-. Grades: >95% by HPLC. CAS No. 30414-16-5. Molecular formula: C30H29N3O16. Mole weight: 687.6.
apo-Milbemycin A3 oxime
apo-Milbemycin A4 oxime
Apomorphine-[13C,d3]
Apomorphine-[13C,d3] is a labelled analogue of Apomorphine which has been used as a dopamine (D1 and D2) receptor agonist, emetic and an antiparkinsonian. Synonyms: (9R)-10-(13C,D3)methyl-10-azatetracyclo[7.7.1.0]heptadeca-1(17),2,4,6,13,15-hexaene-3,4-diol; CS-P-07122; Apomorphine-13C-d3. Grades: > 98%. Molecular formula: C16[13C]H14D3NO2. Mole weight: 271.33.
Apomorphine Sulfate-[d5]
Apomorphine Sulfate-[d5] is an isotope compound of Apomorphine Sulfate, a derivative of Apomorphine. Synonyms: (R)-11-hydroxy-1,2,3,6,8,9-D5-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-10-yl hydrogen sulfate; [(9R)-3-hydroxy-10-methyl(5, 6, 14, 15, 16-D5)-10-azatetracyclo[7.7.1.0, 7.0, 7]heptadeca-1(17), 2, 4, 6, 13, 15-hexaen-4-yl]oxidanesulfonic acid. Grades: > 98%. Molecular formula: C17H17NO5S. Mole weight: 352.42.
Aponicin-1CDYa
Aponicin-1CDYa was found in Rana dybowskii. It has antibacterial activity.
Apoptolidin
Apoptolidin is an apoptosis inducer produced by Nocardiopsis sp. Apoptolidin can induce apoptosis of metastatic cells, but has no effect on normal cells. Synonyms: (1R)-O-2, 6-Dideoxy-3-O-methyl-β-D-arabino-hexopyranosyl-(1?4)-O-2, 6-dideoxy-3-C-methyl-α-L-arabino-hexopyranosyl-(1?8)-3, 5, 7-trideoxy-1-C-[(2S, 4S, 5S, 8E, 10E, 12R, 13R, 14E, 16E, 18E)-12-[(6-deoxy-4-O-methyl-α-L-glucopyranosyl)oxy]-5-hydroxy-4-methoxy-9, 13, 15, 17, 19-pentamethyl-20-oxooxacycloeicosa-8, 10, 14, 16, 18-pentaen-2-yl]-3, 5-dimethyl-9-O-methyl-L-glycero-α-D-galacto-2-nonulopyranose; Apoptolidin A; FU 40A. Grades: ≥95%. CAS No. 194874-06-1. Molecular formula: C58H96O21. Mole weight: 1129.37.
Apoptozole
Apoptozole, also known as Apoptosis Activator VII, is an apoptosis-inducing small molecule that inhibits the ATPase activity of heat shock cognate 70 (Hsc70) and Hsp70 (Kd = 210 and 140 nM, respectively). Apoptozole dose-dependently induces apoptosis in cancer cells (IC50 = 5-7 μM). Synonyms: 4-((2-(3,5-bis(trifluoromethyl)phenyl)-4,5-bis(4-methoxyphenyl)-1H-imidazol-1-yl)methyl)benzamide; Apoptozole; Apoptosis Activator VII. CAS No. 1054543-47-3. Molecular formula: C33H25F6N3O3. Mole weight: 625.57.
Aposcopolamine
Cas No. 535-26-2.
apo-Selamectin aglycone
AppCp
AppCp is a formidable small molecule inhibitor, intelligently studying the enigma of inflammation-related maladies. Its astute focus gravitates towards captivating the capacious CpG oligodeoxynucleotide receptor, thereby orchestrating an exquisite modulation of the immune rejoinder. Synonyms: (AMPPCP); Adenosine-5'-[(β,γ)-methyleno]triphosphate, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C11H18N5O12P3 (free acid). Mole weight: 505.21 (free acid).
AppNH2
AppNH2 is indispensable in research of combating ailments including cancer, diabetes is and autoimmune disorders. This revolutionary creation assuming the role of both a mighty inhibitor and a formidable activator, skillfully honing in on crucial proteins and enzymes entangled in the labyrinthine pathways of pathological advancement. Profoundly effective is appNH2 harnesses its exceptional chemical attributes to govern intricate cellular dynamics, thereby fostering optimal physiological harmony. Synonyms: (AMPPN); Adenosine-5'-(β-amido)diphosphate, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C10H16N6O9P2 (free acid). Mole weight: 426.21 (free acid).
AppNHp
AppNHp is a key recompound used in the biomedical industry for the research of nucleotide analogs and phosphorylation reactions. It plays a crucial role in the development of antiviral drugs, such as AppNHp-based inhibitors for HIV and hepatitis C virus. Synonyms: (AMPPNP); Adenosine-5'-[(β,γ)-imido]triphosphate, Tetralithium salt; AMPPNHP. Grades: ≥ 95% by HPLC. Molecular formula: C10H17N6O12P3 (free acid). Mole weight: 506.19 (free acid).
Apraglutide
Apraglutide is a synthetic long-acting GLP-2 analogue containing 33 amino acids that enhances the adaptation and linear intestinal growth of neonatal piglets in a model of short bowel syndrome with total ileal resection. Synonyms: FE 203799; His-Gly-Asp-Gly-Ser-Phe-Ser-Asp-Glu-Nle-D-Phe-Thr-Ile-Leu-Asp-Leu-Leu-Ala-Ala-Arg-Asp-Phe-Ile-Asn-Trp-Leu-Ile-Gln-Thr-Lys-Ile-Thr-Asp-NH2. Grades: ≥95%. CAS No. 1295353-98-8. Molecular formula: C172H263N43O52. Mole weight: 3765.25.
Apraglutide TFA
Apraglutide TFA is a synthetic long-acting GLP-2 analogue containing 33 amino acids that enhances the adaptation and linear intestinal growth of neonatal piglets in a model of short bowel syndrome with total ileal resection. Synonyms: FE 203799 (TFA); His-Gly-Asp-Gly-Ser-Phe-Ser-Asp-Glu-Nle-D-Phe-Thr-Ile-Leu-Asp-Leu-Leu-Ala-Ala-Arg-Asp-Phe-Ile-Asn-Trp-Leu-Ile-Gln-Thr-Lys-Ile-Thr-Asp-NH2.TFA. Grades: >98%. Molecular formula: C172H263N43O52.C2HF3O2. Mole weight: 3879.27.
Apramycin
Apramycin is an aminoglycoside antibiotic produced by Streptomyces tenebrarius. Apramycin has a broad antibacterial spectrum and has a strong effect on both Gram-positive and negative bacteria. Uses: Anti-bacterial agents. Synonyms: Nebramycin II; Nebramycin factor 2; Apramycinum; Apramicina. Grades: >98%. CAS No. 37321-09-8. Molecular formula: C21H41N5O11. Mole weight: 539.58.
Apramycin Sulfate
Apramycin is an aminoglycoside antibiotic produced by Streptomyces. It has activity against Gram-negative bacteria. It acts by blocking translocation and binding to the eukaryotic decoding site despite differences in key residues required for apramycin recognition by the bacterial target. Uses: Anti-bacterial agents. Synonyms: FEMA 2131; FEMA2131; FEMA-2131. Grades: >98%. CAS No. 65710-07-8. Molecular formula: C21H43N5O15S. Mole weight: 637.66.
Apremilast
Apremilast is an orally available small molecule inhibitor of phosphodiesterase 4 (PDE4). Apremilast specifically inhibits PDE4 and inhibits spontaneous production of TNF-alpha from human rheumatoid synovial cells. Uses: Anti-inflammatory agents, non-steroidal; phosphodiesterase inhibitors. Synonyms: (S)-2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione; (S)-N-(2-(1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide; CC 10004; CC10004; CC-10004. Grades: >98%. CAS No. 608141-41-9. Molecular formula: C22H24N2O7S. Mole weight: 460.50.
Apremilast Dimer
Apremilast Dimer is an impurity of Apremilast, which is an oral phosphodiesterase 4 inhibitor used for treating psoriatic arthritis. Synonyms: (S)-N-(2'-(1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)-1,1',3,3'-tetraoxo-[2,4'-biisoindolin]-4-yl)acetamide. CAS No. 1802246-60-1. Molecular formula: C30H27N3O9S. Mole weight: 605.6.
Apremilast Impurity 2
A metabolite of Apremilast. Synonyms: (R)-Apremilast; N-[2-[(1R)?-1-(3-Ethoxy-4-methoxyphenyl)?-2-(methylsulfonyl)?ethyl]?-2,?3-dihydro-1,?3-dioxo-1H-isoindol-4-yl]?-acetamide. Grades: > 95%. CAS No. 608141-44-2. Molecular formula: C22H24N2O7S. Mole weight: 460.51.
Aprepitant
Aprepitant is a specific NK-1R antagonist, used as an antiemetic agent. Synonyms: 5-[[(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-3H-1,2,4-triazol-3-one; Emend; L 754030; MK 0869; MK 869; ONO 7436. Grades: 98%. CAS No. 170729-80-3. Molecular formula: C23H21F7N4O3. Mole weight: 534.43.
Aprepitant EP Impurity B
Aprepitant EP Impurity B is an impurity of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Synonyms: 3-(((2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(4'-fluoro-[1,1'-biphenyl]-3-yl)morpholino)methyl)-1H-1,2,4-triazol-5(4H)-one. CAS No. 2348441-62-1. Molecular formula: C29H25F7N4O3. Mole weight: 610.52.
Aprepitant EP Impurity C
Aprepitant EP Impurity C is an impurity of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Synonyms: 3-(((2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(4'-fluoro-[1,1'-biphenyl]-4-yl)morpholino)methyl)-1H-1,2,4-triazol-5(4H)-one; 4-Defluoro-4-(p-fluorophenyl)aprepitant. CAS No. 2348441-63-2. Molecular formula: C29H25F7N4O3. Mole weight: 610.52.