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Alyteserin-1d
Alyteserin-1d is an antimicrobial peptide produced by Alytes obstetricans (European midwife toad). It has antibacterial activity. Synonyms: Gly-Leu-Lys-Asp-Ile-Phe-Lys-Ala-Gly-Leu-Gly-Ser-Leu-Val-Lys-Asn-Ile-Ala-Ala-His-Val-Ala-Asn-NH2. Grades: >98%. CAS No. 1159767-80-2. Molecular formula: C106H179N31O28. Mole weight: 2335.79.
Alyteserin-1Ma
Alyteserin-1Ma is an antimicrobial peptide produced by Alytes maurus (Midwife toad). It has antibacterial and antifungal activity. It is active against Gram-negative bacterium: Escherichia coli NCTC 10418 (MIC=214 μM) and Gram-positive bacterium: Staphylococcus aureus NCTC 10788 (MIC=214 μM). Synonyms: Gly-Phe-Lys-Glu-Val-Leu-Lys-Ala-Asp-Leu-Gly-Ser-Leu-Val-Lys-Gly-Ile-Ala-Ala-His-Val-Ala-Asn-NH2. Grades: >98%. Molecular formula: C106H178N30O29. Mole weight: 2336.77.
Alyteserin-1Mb
Alyteserin-1Mb is an antimicrobial peptide produced by Alytes maurus (Midwife toad). It has antibacterial and antifungal activity. It is active against Gram-negative bacterium: Escherichia coli NCTC 10418 (MIC=217 μM) and Gram-positive bacterium: Staphylococcus aureus NCTC 10788 (MIC=434 μM). Synonyms: Gly-Phe-Lys-Glu-Val-Leu-Lys-Ala-Gly-Leu-Gly-Ser-Leu-Val-Lys-Gly-Ile-Pro-Ala-His-Val-Ala-Asn-NH2. Grades: ≥97%. Molecular formula: C106H178N30O27. Mole weight: 2304.77.
Alyteserin-2a
Alyteserin-2a is an antimicrobial peptide produced by Alytes obstetricans (European midwife toad). It has antibacterial activity against Gram-positive bacterium such as Staphylococcus aureus (MIC=50 μM). Synonyms: Ile-Leu-Gly-Lys-Leu-Leu-Ser-Thr-Ala-Ala-Gly-Leu-Leu-Ser-Asn-Leu-NH2. Grades: ≥96%. CAS No. 1159767-81-3. Molecular formula: C72H131N19O20. Mole weight: 1582.95.
Alyteserin-2b
Alyteserin-2b is an antimicrobial peptide produced by Alytes obstetricans (European midwife toad). It has antibacterial activity. Synonyms: Ile-Leu-Gly-Ala-Ile-Leu-Pro-Leu-Val-Ser-Gly-Leu-Leu-Ser-Asn-Lys-Leu-NH2. Grades: >98%. CAS No. 1159767-82-4. Molecular formula: C81H146N20O20. Mole weight: 1720.18.
Alyteserin-2c
Alyteserin-2c is an antimicrobial peptide produced by Alytes obstetricans (European midwife toad). It has antibacterial activity. Synonyms: Ile-Leu-Gly-Ala-Ile-Leu-Pro-Leu-Val-Ser-Gly-Leu-Leu-Ser-Ser-Lys-Leu-NH2. Grades: >98%. CAS No. 1159767-83-5. Molecular formula: C80H145N19O20. Mole weight: 1693.15.
Alyteserin-2Ma
Alyteserin-2Ma is an antimicrobial peptide produced by Alytes maurus (Midwife toad). It has antibacterial and antifungal activity. It is active against Gram-negative bacterium: Escherichia coli NCTC 10418 (MIC=38.4 μM) and Gram-positive bacterium: Staphylococcus aureus NCTC 10788 (MIC=9.5 μM). It only inhibits C. albicans at very high concentration of 150 uM. Synonyms: Phe-Ile-Gly-Lys-Leu-Ile-Ser-Ala-Ala-Ser-Gly-Leu-Leu-Ser-His-Leu-NH2. Grades: ≥97%. Molecular formula: C76H128N20O19. Mole weight: 1625.98.
Alyteserin-2Mb
Alyteserin-2Mb is an antimicrobial peptide produced by Alytes maurus (Midwife toad). It has antibacterial and antifungal activity. It is active against Gram-positive bacterium: Staphylococcus aureus NCTC 10788 (MIC=19.3 μM). It only inhibits C. albicans at very high concentration of 310 uM. Synonyms: Ile-Leu-Gly-Ala-Ile-Ile-Pro-Leu-Val-Ser-Gly-Leu-Leu-Ser-His-Leu-NH2. Grades: ≥96%. Molecular formula: C77H135N19O18. Mole weight: 1615.04.
ALZ-801
ALZ-801 is a novel and orally available prodrug of tramiprosate that is undergoing a clinical trial for the treatment of Alzheimer's disease (AD). Compared to tramiprosate, ALZ-801 improves some critical properties including tolerability, pharmacokinetic and pharmacodynamic profile, as well as metabolic stability. It inhibits the toxic amyloid oligomers formation associated with AD, which is a discovery of new mechanism of AD prevention. Uses: Prevention of alzheimer's disease (ad). Synonyms: ALZ-801; ALZ 801; ALZ801.
AM-0687
This active molecular is a selective PI3Kδ inhibitor. PI3Kδ is hyperactivated in B-cell malignancies and plays a vital role in the B-cell receptor pathway. AM-0687 has Cellular potency: pAKT IC50 = 0.7 nM; HWB, u (pAKT) IC 50 = 4.6 nM. AM-0687 shows excellent potency and selectivity profile in biochemical and cellular assays. Uses: Cancer drug candidate. Synonyms: AM-0687; AM 0687; AM0687. 2 - ((1S) - 1-((6-Amino-5-cyano-4-pyrimidinyl)amino)ethyl)-6-fluoro - N - methyl-3-(2-pyridinyl)-4-quinolinecarboxamide. Grades: 98%. CAS No. 1259522-94-5. Molecular formula: C23H19FN8O. Mole weight: 442.46.
AM095
AM095, an effective LPA1 receptor antagonist, has been found to decrease dermal fibrosis caused by attenuates bleomycin. IC50: 0.98 uM and 0.73 uM for human and mouse LPA1 respectively. Synonyms: AM095 (free acid); AM-095; AM 095. Grades: 98%. CAS No. 1228690-36-5. Molecular formula: C27H24N2O5. Mole weight: 456.49.
AM095 sodium
AM095 is a selective LPA1 receptor antagonist. The IC50 for AM095 antagonism of LPA-induced calcium flux of human or mouse LPA1-transfected CHO cells is 0.025 and 0.023 μM, respectively. Synonyms: AM-095 sodium; AM 095 sodium. Grades: >98%. CAS No. 1345614-59-6. Molecular formula: C27H23N2NaO5. Mole weight: 478.48.
AM-156
Prostanoid GD(2) is released from mast cells in response to allergen challenge. AM156 is a selective prostanoid DP(2) receptor antagonist and it inhibits sneezing and nasal rubs in a model of allergic rhinitis. It can also inhibits pulmonary inflammation and mucus hypersecretion induced by chronic inhalation of house dust mite. AM156 may be have beneficial effects for treatment of allergic rhinitis and asthma in the future. Uses: Allergic rhinitis and asthma. Synonyms: AM-156; AM 156; AM156; UNII-5V9HJQ1Y75;sodium 2-(2'-((N-ethylcyclopropanecarboxamido)methyl)-6-methoxy-4'-(trifluoromethyl)-[1,1'-biphenyl]-3-yl)acetate;1175525-98-0 (AM-156 free acid). Grades: 98%. CAS No. 1224977-85-8. Molecular formula: C23H23F3NNaO4. Mole weight: 457.42.
AM-156 sodium
AM-156 is a bio-active chemical and detailed information has not been published yet. Synonyms: AM-156 sodium; AM 156 sodium; AM156 sodium; sodium 2-(2'-((N-ethylcyclopropanecarboxamido)methyl)-6-methoxy-4'-(trifluoromethyl)-[1,1'-biphenyl]-3-yl)acetate,UNII-5V9HJQ1Y75,1175525-98-0 (AM-156 free acid). Grades: 98%. CAS No. 1175525-98-0. Molecular formula: C23H23F3NNaO4. Mole weight: 457.42.
AM-206
AM-206 is a bio-active chemical but no detailed data has been published yet. Synonyms: AM-206; AM 206; AM206; 3-Pyridineacetic acid, 5- (2- ( (ethyl ( (phenylmethoxy) carbonyl) amino) methyl) -4- (trifluoromethyl) phenyl) -, sodium salt (1:1); UNII-NCZ7ZWF0CR;1219935-54-2 (AM-206 free acid). Grades: 98%. CAS No. 1224977-86-9. Molecular formula: C25H22F3N2NaO4. Mole weight: 494.44.
AM-206 sodium
AM-206 is a bio-active chemical but no detailed data has been published yet. Synonyms: AM-206; AM 206; AM206; UNII-NCZ7ZWF0CR;(5-(2-((N-((Benzyl)oxycarbonyl)-N-ethylamino)methyl)-4-trifluoromethylphenyl)pyridin-3-yl)acetic acid. Grades: 98%. CAS No. 1219935-54-2. Molecular formula: C25H23F3N2O4. Mole weight: 472.46.
AM-211
This active molecular is a potent Prostaglandin D2 receptor antagonists and has been in phase I clinical trials for both COPD (chronic obstructive pulmonary disease) and asthma, but no recent results has been published. Uses: Chronic obstructive pulmonary disease(copd) and asthma. Synonyms: AM-211; AM 211; AM211; 2-(2'-((3-benzyl-1-ethylureido)methyl)-6-methoxy-4'-(trifluoromethyl)-[1,1'-biphenyl]-3-yl)acetic acid,1263077-74-2 (AM-211 sodium). Grades: 98%. CAS No. 1175526-27-8. Molecular formula: C27H27F3N2O4. Mole weight: 500.51.
AM-211 sodium
This active molecular is a potent Prostaglandin D2 receptor antagonists and has been in phase I clinical trials for both COPD (chronic obstructive pulmonary disease) and asthma, but no recent results has been published. Uses: Chronic obstructive pulmonary disease(copd) and asthma. Synonyms: UNII-8SV621U288;1175526-27-8(Free acid); AM-211 sodium; AM 211 sodium; AM211 sodium. Grades: 98%. CAS No. 1263077-74-2. Molecular formula: C27H26F3N2O4Na. Mole weight: 522.50.
AM-2159
AM-2159 is a bio-active chemical, but no detailed information has been published yet. Synonyms: AM-2159; AM 2159; AM2159; N6-((4-chlorophenyl)methyl)-N6-methyl- 2,4,6-Quinazolinetriamine. Grades: 98%. CAS No. 83654-06-2. Molecular formula: C16H16ClN5. Mole weight: 313.78.
AM3102
AM-3102 is an Oleoyl ethanolamide (OEA) analog that stimulates PPARα transcriptional activity with an EC50 value of 100 nM and prolongs feeding latency. The biological effects of OEA are terminated by N-acylethanolamine-hydrolyzing acid amidase and fatty-acid amide hydrolase. AM3102 demonstrates weak affinity for the central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors with Ki values of 33 and 26 μM, respectively. Synonyms: KDS-5104; AM-3102; AM 3102; Methyl oleoylethanolamide. Grades: ≥98%. CAS No. 213182-22-0. Molecular formula: C21H41NO2. Mole weight: 339.6.
AM404
AM-404 is a selective inhibitor of the carrier-mediated transport of anandamide without affecting anandamide hydrolysis. AEM is also an analog of arachidonyl ethanolamide (AEA) which potentiates the activity of endogenous AEA by blocking its reuptake into presynaptic neurons. AM404 inhibits endocannabinoid cellular uptake, binds weakly to CB1 and CB2 cannabinoid receptors, and is formed by fatty acid amide hydrolase (FAAH) in vivo. Synonyms: 5,8,11,14-Eicosatetraenamide, N-(4-hydroxyphenyl)-, (5Z,8Z,11Z,14Z)-; (5Z,8Z,11Z,14Z)-N-(4-Hydroxyphenyl)-5,8,11,14-eicosatetraenamide; 5,8,11,14-Eicosatetraenamide, N-(4-hydroxyphenyl)-, (all-Z)-; AM 404; AM404. Grades: ≥98%. CAS No. 183718-77-6. Molecular formula: C26H37NO2. Mole weight: 395.58.
AM 4299 A
AM 4299 A is a thiol protease inhibitor produced by Chromelosporium fulvum M4299. Synonyms: Oxiranecarboxylic acid, 3-(((1-(((5-hydroxypentyl)amino)carbonyl)-3-methylbutyl)amino)carbonyl)-. Grades: >98%. CAS No. 160825-48-9. Molecular formula: C15H26N2O6. Mole weight: 330.38.
AM 4299 B
AM 4299 B is a thiol protease inhibitor produced by Chromelosporium fulvum M4299. Synonyms: N(sup 6)-(N-((3-Carboxyoxiranyl)carbonyl)-L-leucyl)-L-lysine hydrate. Grades: >98%. CAS No. 160825-49-0. Molecular formula: C16H27N3O7. Mole weight: 373.40.
AM580
AM580 is a selective RARα agonist. It was shown to induce differentiation of human induced pluripotent stem cells into intermediate mesoderm. Synonyms: AM-580; 4-[(5,5,8,8-tetramethyl-6,7-dihydronaphthalene-2-carbonyl)amino]benzoic acid. Grades: >98%. CAS No. 102121-60-8. Molecular formula: C22H25NO3. Mole weight: 351.44.
AM-643
AM-643 is an active molecular. In the Biological Tests, it can inhibit FLAP in human whole blood assessed as inhibition of calcium ionophore A23187-induced LTB4 production preincubated for 5 hrs by ELISA and the activity value is 0.081μM. It can also Inhibit COX1-mediated TXB2 production in human whole blood after 30 mins by competitive enzyme immunoassay and the activity value is 25μM. Synonyms: AM-643 Free Acid; AM643 Free Acid; UNII-55668SZQ3E;3-(3-(tert-butylthio)-1-(4-(5-methoxypyrimidin-2-yl)benzyl)-5-((5-methylpyridin-2-yl)methoxy)-1H-indol-2-yl)-2,2-dimethylpropanoic acid. Grades: 98%. CAS No. 1233114-22-1. Molecular formula: C36H40N4O4S. Mole weight: 642.79.
AM-8508
AM-8508 is a selective Phosphatidylinositol-3-kinase delta (PI3Kδ) inhibitor. AM-8508 exhibits good cellular potency (in vitro pAKT IC50 = 4.6 nM ) and excellent HWB potency (HWB (pAKT) IC50 = 2.7 nM). AM-8508 inhibits KLH-specific antibodies in animal models and it may become a drug candidate for the treatment of human inflammatory diseases. Uses: Inflammatory diseases. Synonyms: AM-8508; AM 8508; AM8508. (S)-4-amino-6-((1-(6-fluoro-1-(pyridin-3-yl)-1H-benzo[d]imidazol-2-yl)ethyl)amino)pyrimidine-5-carbonitrile. Grades: 98%. CAS No. 1338483-67-2. Molecular formula: C19H15FN8. Mole weight: 374.14.
AM-9635
AM-9635 is a selective Phosphatidylinositol-3-kinase delta (PI3Kδ) inhibitor. AM-9635 exhibits good cellular potency (in vitro pAKT IC50 = 4.2 nM ). AM-9635 can inhibit KLH-specific IgG and IgM in a dosedependent manner and it is well tolerated at all doses. AM-96352 shows significantly reduced IgG and IgM specific antibodies. Synonyms: AM-9635; AM 9635; AM9635. (S)-4-amino-6-((1-(6-fluoro-1-(5-fluoropyridin-3-yl)-1H-benzo[d]imidazol-2-yl)ethyl)amino)pyrimidine-5-carbonitrile. Grades: 98%. CAS No. 1338483-10-5. Molecular formula: C19H14F2N8. Mole weight: 392.36.
AM 966
AM966, a LPA1 receptor antagonist, has been found to restrain lung fibrosis in mouse model. IC50: 17 nM. Uses: Am966 is a lpa1 receptor antagonist that has been found to restrain lung fibrosis in mouse model. Synonyms: AM-966; AM 966; AM966; 2-[4-[4-[4-[[(1R)-1-(2-chlorophenyl)ethoxy]carbonylamino]-3-methyl-1,2-oxazol-5-yl]phenyl]phenyl]aceticacid;AM966;AM-966;UNII-CEO54NH393;1228690-19-4;(R)-2-(4'-(4-(((1-(2-Chlorophenyl)ethoxy)carbonyl)amino)-3-methylisoxazol-5-yl)-[1,1'-biphenyl]-4-yl)acet. Grades: 95%. CAS No. 1228690-19-4. Molecular formula: C27H23ClN2O5. Mole weight: 490.93.
a-Maltotetraosyl-a,a-trehalose
a-Maltotetraosyl-a,a-trehalose is an intricate and cutting-edge compound breakthrough, holding immense potential in the realm of studying an array of diseases such as neurodegenerative disorders and metabolic anomalies. CAS No. 171609-69-1. Molecular formula: C36H62O31. Mole weight: 990.86.
Amantadine
Amantadine can be used as an antiviral and an antiparkinsonian drug. It is a NMDA receptor antagonist. Amantadine is also a useful building block in organic synthesis, allowing the insertion of an adamantyl group. Uses: Antiparkinson agents; antiviral agents; dopamine agents. Synonyms: adamantan-1-amine. Grades: > 95 %. CAS No. 768-94-5. Molecular formula: C10H17N. Mole weight: 151.25.
Amantadine Hydrochloride
Amantadine Hydrochloride is a NMDA-receptor antagonist acts as an antiviral and an antiparkinsonian drug. Uses: Dopaminergic agent. antiviral. Synonyms: 1-Adamantanamine hydrochloride; adamantan-1-amine;hydrochloride. Grades: 95%. CAS No. 665-66-7. Molecular formula: C10H18ClN. Mole weight: 187.71.
Amaranth
Amaranth is a food pigment additive, which can cause DNA damage difference in colon of rats and mice. Uses: Indicators and reagents. Synonyms: Bordeaux S; 1-(4-Sulfo-1-naphthylazo)-2-naphthol-3,6-disulfonic Acid Trisodium Salt; 1302 Red; 1508 Red; 2-Hydroxy-1,1'-azonaphthalene-3,6,4'-trisulfonic Acid Trisodium Salt; Acid Amaranth; Acid Amaranth I; Acid Amaranth J; Acid Amaranth N; Acid Leather Rubine S; Acid Red 27; Aizen Amaranth; Amaranth A; Amaranth B; Amaranth BPC; Amaranth Extra; Amaranth Lake; Amaranth R; Amaranth S; Amaranth red; Amaranthe; Azo Red R; Azo Rubine SF; Azo Ruby S; Azorubin S. Grades: >95%. CAS No. 915-67-3. Molecular formula: C20H11N2Na3O10S3. Mole weight: 604.47.
AMARA peptide TFA
AMARA peptide TFA is a substrate for salt-induced kinase (SIK) and adenosine monophosphate-activated protein kinase (AMPK). Synonyms: Ala-Met-Ala-Arg-Ala-Ala-Ser-Ala-Ala-Ala-Leu-Ala-Arg-Arg-Arg.TFA; L-alanyl-L-methionyl-L-alanyl-L-arginyl-L-alanyl-L-alanyl-L-seryl-L-alanyl-L-alanyl-L-alanyl-L-leucyl-L-alanyl-L-arginyl-L-arginyl-L-Arginine trifluoroacetic acid. Grades: >98%. Molecular formula: C62H115N27O17S.C2HF3O2. Mole weight: 1656.83.
Amarogentin
Amarogentin exhibits anti-oxidative, anti-tumour, and anti-diabetic activities. Amarogentin promotes apoptosis, arrests G2/M cell cycle and downregulates of PI3K/Akt/mTOR signalling pathways and displays immunomodulatory effects in human mast cells and keratinocytes. It inhibits the growth of SNU-16 human gastric cancer cells (IC50 = 12.4 μM) and increases apoptosis when used at a concentration of 50 μM. Amarogentin dose-dependently reduces tumor growth in a SNU-16 nude mouse xenograft model. Amarogentin may offer therapeutic potential for preventing or treating thromboembolic disorders, it prevents platelet activation through the inhibition of PLC γ2-PKC cascade and MAPK pathway. Synonyms: Amarogentin; 21018-84-8; 5L82GT5I0W; [(2S,3R,4S,5S,6R)-2-[[(3S,4R,4aS)-4-ethenyl-8-oxo-4,4a,5,6-tetrahydro-3H-pyrano[3,4-c]pyran-3-yl]oxy]-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl] 2,4-dihydroxy-6-(3-hydroxyphenyl)benzoate; sweroside-2'-(3'',5'',3'''-trihydroxydiphenyl)-2''-carboxylic acid ester; (4aR)-5t-ethenyl-6c-[O(2)-(3,5,3'-trihydroxybiphenyl-2-ylcarbonyl)-beta-D-glucopyranosyloxy]-4,4ar,5,6-tetrahydro-3H-pyrano[3,4-c]pyran-1-one; (4aS,5R,6S)-5-ethenyl-1-oxo-4,4a,5,6-tetrahydro-1H,3H-pyrano[3,4-c]pyran-6-yl- 2-O-[(3,3',5-trihydroxybiphenyl-2-yl)carbonyl]-beta-D-glucopyranoside. Grades: ≥98%. CAS No. 21018-84-8. Molecular formula: C29H30O13. Mole weight: 586.54.
AMAR peptide
AMAR peptide is used to measure AMPK-related kinase activity. Grades: >98%. CAS No. 163560-19-8. Molecular formula: C62H115N27O17S. Mole weight: 1542.81.
Amaryllin (1-15)
Amaryllin is an antimicrobial peptide produced by Amaryllis belladonna (Naked lady lily). It has antifungal activity. Synonyms: Gln-Lys-Ile-Gln-Glu-Ile-Asp-Leu-Gln-Thr-Tyr-Leu-Gln-Pro-Gln; Amaryllin (Plant defensin); Amaryllin. Grades: >96%. Molecular formula: C82H133N21O27. Mole weight: 1845.09.
Amberlite LA-2
Cas No. 11128-96-4.
Ambrisentan Acyl β-D-Glucuronide
A metabolite of Ambrisentan. Synonyms: 1-[(αS)-α-[(4,6-Dimethyl-2-pyrimidinyl)oxy]-β-methoxy-β-phenylbenzenepropanoate] β-D-Glucopyranuronic Acid. Grades: > 95%. CAS No. 1106685-58-8. Molecular formula: C28H30N2O10. Mole weight: 554.56.
Ambrisentan Hydroxy Acid Impurity
A metabolite of Ambrisentan. Synonyms: (S)-2-Hydroxy-3-methoxy-3,3-diphenylpropionic Acid. Grades: > 95%. CAS No. 178306-52-0. Molecular formula: C16H16O4. Mole weight: 272.3.
Ambrisentan Impurity E
A metabolite of Ambrisentan. Synonyms: 2-[(4,6-Dimethyl-2-pyrimidinyl)oxy]-3,3-diphenyl-2-propenoic Acid. Grades: > 95%. CAS No. 1312092-82-2. Molecular formula: C21H18N2O3. Mole weight: 346.39.
Ambrisentan Vinyloxy Impurity
A metabolite of Ambrisentan. Synonyms: 2-((2,2-Diphenylvinyl)oxy)-4,6-dimethylpyrimidine. Grades: > 95%. CAS No. 1639429-81-4. Molecular formula: C20H18N2O. Mole weight: 302.38.
Ambrox
Ambrox is obtained from ambergris produced by sperm whales. It is an autoxidation product of ambrein and is a naturally occurring terpenoid. It is also one of the key components of natural Ambergris. It is a fragrance ingredient and is used to make amber fragrance. It is also used as a flavoring in food and a good functional cosmetics raw material. Synonyms: [3aR-(3aalpha,5abeta,9aalpha,9bbeta)]-dodecahydro-3a,6,6,9a-tetramethylnaphtho[2,1-b]furan; Amberoxan; Ambropur; Naphtho2,1-bfuran, dodecahydro-3a,6,6,9a-tetramethyl-, (3aR,5aS,9aS,9bR)-; 1,5,5,9-Tetramethyl-13-oxatricyclo[8.3.0.04,9]tridecane; (-)-Ambroxide; (-)-Norlabdane Oxide; Amberlyn Super; 8alpha, 12-Oxido-13,14,15,16-tetranorlabdane. Grades: 99.0%. CAS No. 6790-58-5. Molecular formula: C16H28O. Mole weight: 236.39.
Ambroxol
Ambroxol is a secretolytic agent to treat airway infections connected with viscid or excessive mucus. Synonyms: 4-[(2-amino-3,5-dibromophenyl)methylamino]cyclohexan-1-ol; 4- ( ( (2-Amino-3, 5-dibromophenyl) methyl) amino) cyclohexanol; AbrohexalAM, Bisolvon; Ambril; Ambro Puren; Ambro-Puren; Ambrobeta; Ambrofur; Ambrohexal; Ambrolös; Ambrolitic; AMBROPP; AmbroPuren; Ambroten; Ambroxin. CAS No. 18683-91-5. Molecular formula: C13H18Br2N2O. Mole weight: 378.10.
Ambroxol-[13C7,d] hydrochloride
Ambroxol-[13C7,d] hydrochloride is an isotopic labelled Ambroxol HCl. Ambroxol HCl is a potent inhibitor of the neuronal Na+ channels, inhibits TTX-resistant Na+ currents with IC50 of 35.2 μM and 22.5 μM for tonic and phasic block, inhibits TTX-sensitive Na+ currents with IC50 of 100 μM. Synonyms: 4-({[2-amino-3, 5-dibromo(1, 2, 3, 4, 5, 6-13C6)phenyl](13C, 2H1)methyl}amino)cyclohexan-1-ol hydrochloride. Molecular formula: C6[13C]7H18DBr2ClN2O. Mole weight: 422.52.
Ambroxol Cyclic Impurity-[d5] Dihydrochloride
Ambroxol Cyclic Impurity-[d5] dihydrochloride is the labelled salt of Ambroxol Cyclic Impurity, which is a metabolite as well as an impurity of the bronchosecretolytic drug, Ambroxol. Synonyms: Ambroxol Cyclic Impurity-d5 dihydrochloride; trans-4-(6,8-Dibromo-1,4-dihydro-3(2H)-quinazolinyl)cyclohexanol-d5 Dihydrochloride; NA 873-d5 Dihydrochloride; Ambroxol EP Impurity B-d5 Dihydrochloride; Cyclohexan-1,2,2,6,6-d5-ol, 4-(6,8-dibromo-1,4-dihydro-3(2H)-quinazolinyl)-, (1α,4β)-, dihydrochloride. Molecular formula: C14H15D5Br2Cl2N2O. Mole weight: 468.07.
Ambroxol Cycloimine
5-ethyl 3-isopropyl 2-((2-aminoethoxy)methyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate is an impurity of Ambroxol, a medication used in the treatment of respiratory diseases associated with viscid or excessive mucus. Synonyms: (trans)-4-(6,8-dibromoquinazolin-3(4H)-yl)cyclohexanol; N-{[(2S)-1-Ethyl-2-pyrrolidinyl]methyl}-5-(ethylsulfonyl)-2-methoxy-4-(methylamino)benzamide; (1R,4R)-4-(6,8-dibromoquinazolin-3(4H)-yl)cyclohexan-1-ol; Ambroxol Cycloimine Impurity. CAS No. 2088879-81-4. Molecular formula: C18H29N3O4S. Mole weight: 383.51.
Ambroxol Cycloimine Impurity
An impurity of Ambroxol. Synonyms: 4-(6,8-Dibromo-3(4H)-quinazolinyl)-cyclohexanol. Grades: > 95%. CAS No. 1797894-71-3. Molecular formula: C14H16Br2N2O. Mole weight: 388.1.
Ambroxol-[d10]
Ambroxol-[d10] is a labelled compound of Ambroxol, a secretolytic agent to treat airway infections connected with viscid or excessive mucus. Synonyms: trans-4-((2-amino-3,5-dibromobenzyl)amino)cyclohexanol-D10. Grades: > 98%. Molecular formula: C13H8D10Br2N2O. Mole weight: 388.16.
Ambroxol-[d5]
Ambroxol-[d5] is a labelled compound of Ambroxol, a secretolytic agent to treat airway infections connected with viscid or excessive mucus. Grades: > 98%. CAS No. 1246818-80-3. Molecular formula: C13H13D5Br2N2O. Mole weight: 383.13.
Ambroxol HCl
Cas No. 23828-92-4.
Ambroxol Impurity B
Cas No. 18683-95-9.
Ambroxol Impurity C
Cas No. 50910-53-7.
Ambroxol Impurity D HCl
Cas No. 1384955-66-1.
Ambroxol Monobromine
An impurity of Ambroxol, a medication used in the treatment of respiratory diseases associated with viscid or excessive mucus. Synonyms: trans-4-[[(2-Amino-5-bromophenyl)methyl]amino]-cyclohexanol. Grades: > 95%. CAS No. 101900-43-0. Molecular formula: C13H19BrN2O. Mole weight: 299.21.
Ambuic acid
Ambuic acid is a cyclohexanone originally isolated from Pestalotiopsis and Monochaetia species. Antibiotic medications are widely used in the treatment and prevention of such infections. They may either kill or inhibit the growth of bacteria. It is active against P. ultimum (MIC = 7.5 μg/ml) and inhibits the growth of a variety of other phytopathogenic fungi. Ambuic acid inhibits the biosynthesis of cyclic peptides involved in quorum sensing, including gelatinase biosynthesis-activating pheromone (GBAP). Synonyms: (+)-Ambuic acid; (2E,5R,6R,7R,8E,10E)-2-Methyl-5,9-carbonyl-5,6-epoxy-7-hydroxy-8-(hydroxymethyl)-2,8,10-hexadecatrienoic acid. Grades: ≥95%. CAS No. 340774-69-8. Molecular formula: C19H26O6. Mole weight: 350.41.
AMCA-6-dUTP
AMCA-6-dUTP is a fluorescent probe commonly used in the biomedical industry to label DNA during various molecular biology applications. It can be incorporated into DNA using DNA polymerase and serving as a valuable tool for visualizing and studying DNA replication, repair and recombination. Synonyms: Aminoallyl-dUTP - AMCA; Aminomethylcoumarin-6-dUTP; Aminomethylcoumarin-5-aminoallyl-2'-deoxyuridine-5'-triphosphate, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C30H40N5O18P3 (free acid). Mole weight: 851.58 (free acid).
Amcinonide
Amcinonide is a corticosteroid (IC50 = 3.38 nM) used as an anti-inflammatory and antipruritic agent. Uses: Anti-inflammatory agent. Synonyms: cl-34699; cyclocort; Amciderm; Amcinonid; Penticort. Grades: ≥98%. CAS No. 51022-69-6. Molecular formula: C28H35FO7. Mole weight: 502.58.
AMD-070 hydrochloride
AMD-070 hydrochloride is a potent and selective antagonist of CXCR4 with an IC50 value of 13 nM in a CXCR4 125I-SDF inhibition binding assay. Synonyms: AMD070 hydrochloride; AMD 070 hydrochloride; (S)-N1-((1H-benzo[d]imidazol-2-yl)methyl)-N1-(5,6,7,8-tetrahydroquinolin-8-yl)butane-1,4-diamine trihydrochloride. CAS No. 880549-30-4. Molecular formula: C21H30Cl3N5. Mole weight: 458.86.
Amdinocillin
Mainly resistant to gram-negative bacteria. Uses: Active antibacterial against gram-negative bacteria. Synonyms: Mecillinam. Grades: ≥95%. CAS No. 32887-01-7. Molecular formula: C15H23N3O3S. Mole weight: 325.43.
Amdizalisib is a phosphatidylinositol 3-kinase (PI3K) inhibitor, an immunomodulator and an antineoplastic. Synonyms: (S)-4-amino-6-((1-(3-chloro-6-phenylimidazo[1,2-b]pyridazin-7-yl)ethyl)amino)pyrimidine-5-carbonitrile. Grades: 99% by HPLC. CAS No. 1894229-05-0. Molecular formula: C19H15ClN8. Mole weight: 390.83.
Amedalin Hydrochloride
Amedalin Hydrochloride, with antidepressant effect, is a selective norepinephrine reuptake inhibitor. Synonyms: 3-methyl-3-[3-(methylamino)propyl]-1-phenylindol-2-one;hydrochloride; Amedalin HCl. Grades: >98%. CAS No. 22232-73-1. Molecular formula: C19H23ClN2O. Mole weight: 330.85.
Amenamevir
Amenamevir is a DNA helicase-primase inhibitors. It has anti-HSV activity against herpes simplex keratitis. In Mar 2016, Mahuro completed a phase III trial in Herpes simplex virus infections in Japan. Uses: Herpes simplex virus infections; herpes zoster. Synonyms: UNII-94X46KW4AE; ASP2151; N-(2,6-dimethylphenyl)-N-[2-[4-(1,2,4-oxadiazol-3-yl)anilino]-2-oxoethyl]-1,1-dioxothiane-4-carboxamide. Grades: 98%. CAS No. 841301-32-4. Molecular formula: C24H26N4O5S. Mole weight: 422.55.
Amentoflavone
Amentoflavone, a natural flavonoid isolated from the the seed of Ginkgo biloba L, exhibits anti-inflammatory activity, and inhibits NF-κB/DNA binding activity potently along with inhibition of degradation of IκBα and NF-κB translocation into nucleus in TNFα-activated A549 cells. Amentoflavone has the inhibition of LPS-induced NO formation, due to its inhibition of NF-kappaB by blocking degradation, which may be the mechanistic basis of the anti-inflammatory effects of amentoflavone. Uses: Cytochrome p-450 cyp2c9 inhibitors. Synonyms: 4H-1-Benzopyran-4-one, 8-[5-(5,7-dihydroxy-4-oxo-4H-1-benzopyran-2-yl)-2-hydroxyphenyl]-5,7-dihydroxy-2-(4-hydroxyphenyl)-; 3''',8-Biflavone, 4',4''',5,5'',7,7''-hexahydroxy-; 8-[5-(5,7-Dihydroxy-4-oxo-4H-1-benzopyran-2-yl)-2-hydroxyphenyl]-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; Ginkgetin, didemethyl-; Amenthoflavone; I3',II8-Biapigenin; NSC 295677; Tridemethylsciadopitysin. Grades: >98%. CAS No. 1617-53-4. Molecular formula: C30H18O10. Mole weight: 538.46.
Ametantrone
Ametantrone (AM) is a topoisomerase II inhibitor leading to covalent cross-links in DNA of tumor cells. It is a synthetic 9,10-anthracenedione containing two (hydroxyethylamino)ethylamino residues at positions 1 and 4. Along with other anthraquinones and anthracyclines, it shares a polycyclic intercalating moiety and charged side chains that stabilize DNA binding. Synonyms: CI881; CI 881; CI-881; NSC196473; NSC 287513; NSC-196473; NSC 287513; 1, 4-bis[2- (2-hydroxyethylamino) ethylamino]anthracene-9, 10-dione. CAS No. 64862-96-0. Molecular formula: C22H28N4O4. Mole weight: 412.49.
Ametoctradin
Ametoctradin ist eine chemische Verbindung aus der Gruppe der Triazol-Pyrimidylamine. Synonyms: 5-Ethyl-6-octyl[1,2,4]?triazolo[1,5-a]pyrimidin-7-amin. Grades: > 95%. CAS No. 865318-97-4. Molecular formula: C15H25N5. Mole weight: 275.4.
Amfenac
Amfenac (2-Amino-3-benzoylbenzeneacetic acid) is a non-steroidal anti-inflammatory drug with acetic acid moiety. Synonyms: 2-Amino-3-benzoylphenylacetic acid; 2-Amino-3-benzoylbenzeneacetic acid; 2-(2-amino-3-benzoyl-phenyl)acetic acid. Grades: > 95%. CAS No. 51579-82-9. Molecular formula: C15H13NO3. Mole weight: 255.28.
Amfenac Lactam
A metabolite of Amfenac. Synonyms: 7-Benzoyl-1,3-dihydro-2H-indol-2-one; 7-Benzoyl-2-indolinone. Grades: > 95%. CAS No. 51135-38-7. Molecular formula: C15H11NO2. Mole weight: 237.26.
Amfonelic acid
Amfonelic acid (AFA; WIN 25,978) is a research chemical and dopaminergic stimulant with antibiotic properties. Synonyms: AMFONELIC ACID; AMFONELIC ACID INCREASES DOPAMINE RE; amfonelic acid (7-benzyl-1-ethyl-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid); Amfonelic; 7-Benzyl-1-ethyl-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid; NCA. Grades: 95%. CAS No. 15180-02-6. Molecular formula: C18H16N2O3. Mole weight: 308.33.
AMG-126737
AMG-126737 is a potent inhibitor of human lung mast cell tryptase (Ki = 90 nM), with greater than 10- to 200-fold selectivity versus other serine proteases. Synonyms: 3- [ [4- [5- [4- [ [ (3-carbamimidoylphenyl) sulfonylamino] methyl] phenoxy] pentoxy] phenyl] methylsulfamoyl] benzenecarboximidamide; 1,5-bis-(4-((3-carbamimidoyl-benzenesulfonylamino)-methyl)-phenoxy)-pentane; AMG-126737; AMG 126737; AMG126737. Grades: >98%. CAS No. 224054-76-6. Molecular formula: C33H38N6O6S2. Mole weight: 678.82.