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Azepane-1-carbonyl-Leu-D-Trp(For)-D-Trp-OH
Azepane-1-carbonyl-Leu-D-Trp(For)-D-Trp-OH, a very potent ET-A receptor antagonist, is about 30000 times more selective for ET-A receptors than for ET-B receptors. It has strong antagonistic effect on ET-1 induced concentration in porcine coronary artery with a pA2 value of 8.2. Synonyms: BQ-610; N-[(Hexahydro-1H-azepin-1-yl)carbonyl]-L-leucyl-1-formyl-D-tryptophyl-D-tryptophan; N-[1-Formyl-N-[N-[(hexahydro-1H-azepin-1-yl)carbonyl]-L-leucyl]-D-tryptophyl]-D-tryptophan; Hexahydroazepinocarbonyl-leu-D-trp(cho)-D-trp; Hexahydroazepinocarbonyl-leucyl-tryptophyl(cho)-tryptophan; (R)-2-((R)-2-((S)-2-(azepane-1-carboxamido)-4-methylpentanamido)-3-(1-formyl-1H-indol-3-yl)propanamido)-3-(1H-indol-3-yl)propanoic acid; N-(1-Azepanylcarbonyl)-L-leucyl-1-formyl-D-tryptophyl-D-tryptophan. Grade: ≥95% by HPLC. CAS No. 141595-53-1. Molecular formula: C36H44N6O6. Mole weight: 656.77.
Azidamfenicol
Azidamfenicol is a semi-synthetic chloramphenicol in which the nitro moiety is replaced with a methylsulphone and the dichloroacetamide is replaced with azidoacetamide. It is a broad spectrum antibiotic with good activity against gram-negative and anaerobic bacteria. Azidamfenicol acts by binding to the 23S sub-unit of the 50S ribosome, inhibiting protein synthesis. Azidamfenicol has received little research attention with only a few literature citations. Synonyms: Azidoamphenicol; Leukomycin N. Grade: >99% by HPLC. CAS No. 13838-08-9. Molecular formula: C11H13N5O5. Mole weight: 295.25.
Azido-C3-UV-biotin is a polyethylene glycol (PEG)-based PROTAC linker. Azido-C3-UV-biotin can be used in the synthesis of a series of PROTACs. Synonyms: UV Cleavable Biotin-PEG2-alkyne. Molecular formula: C38H48N4O9S. Mole weight: 736.87.
Azithromycin
Azithromycin is produced by the strain of Erythromycin. The antibacterial activity and pharmacokinetic properties are better than erythromycin, and it is widely used in clinic. Synonyms: (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-[(2,6-Dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-1-oxa-6-azacyclopentadecan15-one; 1-Oxa-6-azacyclopentadecan-15-one, 13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-, [2R-(2R*,3S*,4R*,5R*,8R*,10R*,11R*,12S*,13S*,14R*)]-; 9-Deoxo-9a-methyl-9a-aza-9a-homoetrythromycin A; Aruzilina; Arzomicin; Auricin; Auricin (polyketide antibiotic); Azadose; AzaSite; Azatril; Azee; Azenil; Azimin; Aziromycin; Azisara; Azithral; Azithrocin; Azithromycin A; Azitrocin; Azitromax; Aziwin; Aziwok; AZM; Azomycin; Azomycin (macrolide); Aztrin; CP 62993; Durasite; Hemomycin; Macromycin; Macrozit; N-Methyl-11-aza-10-deoxo-10-dihydroerythromycin A; Sanhe; Setron; Shimen; Sumamed; Sumazid; Tobil; Tridosil; Tromix; Trozocina; Ultreon; Xithron; Xithrone. Grade: >98%. CAS No. 83905-01-5. Molecular formula: C38H72N2O12. Mole weight: 748.98.
Azithromycin dihydrate
Azithromycin dihydrate is the dihydrate form of azithromycin, an orally bioavailable azalide derived from erythromycin, and a member of a subclass of macrolide antibiotics, with anti-bacterial activity. Azithromycin is marginally less active than erythromycin in vitro against Gram-positive organisms, although this is of doubtful clinical significance as susceptibility concentration fall within the range of achievable tissue Azithromycin concentrations. Uses: Anti-bacterial agents. Synonyms: Azitro; CP 62993; CP-62993; CP62993; Goxal; Odaz; Ribotrex; Toraseptol; Ultreon; XZ-450; XZ450; XZ 450; Zenstavion; Zithromax; Zmax; 1-Oxa-6-azacyclopentadecan-15-one, 13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-, dihydrate, [2R-(2R*,3S*,4R*,5R*,8R*,10R*,11R*,12S*,13S*,14R*)]-; Azrolid; Zithrokan; Zithromac; (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-[(2,6-Dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-1-oxa-6-azacyclopentadecan-15-one dihydrate. Grade: >98%. CAS No. 117772-70-0. Molecular formula: C38H72N2O12.2H2O. Mole weight: 785.02.
Azlocillin sodium salt
Azlocillin is an acylampicillin antibiotic with an extended spectrum of activity and greater in vitro potency than the carboxy penicillins. Azlocillin is similar to mezlocillin and piperacillin. It demonstrates antibacterial activity against a broad spectrum of bacteria, including Pseudomonas aeruginosa and, in contrast to most cephalosporins, exhibits activity against enterococci. Uses: Anti-bacterial agents. Synonyms: Bayer Brand of Azlocillin; Sodium Azlocillin; Securopen; Bay-e 6905; Baye 6905; Bay e 6905; Azlocillin; Azlocillin Bayer Brand. Grade: >98%. CAS No. 37091-65-9. Molecular formula: C20H23N5O6SNa. Mole weight: 484.48.
Azomycin
It is produced by the strain of Nocardia mesenterica 446-8A. Azomycin is an antimicrobial antibiotic produced by a strain of Nocardia mesenterica. It has the activity against gram-positive bacteria, negative bacteria, branch bacteria and trichomonas vaginalis, and has a weak inhibitory effect on Ehrlician ascites cancer. Synonyms: 2-Nitroimidazole. Grade: >98%. CAS No. 527-73-1. Molecular formula: C3H3N3O2. Mole weight: 113.07.
AZP-531
AZP-531 is designed to improve glycaemic control and reduce weight with potential for the treatment of Prader-Willi syndrome. Synonyms: cyclo[Arg-Val-Gln-Ser-Pro-Glu-His-Gln]; cyclo[L-arginyl-L-valyl-L-glutaminyl-L-seryl-L-prolyl-L-alpha-glutamyl-L-histidyl-L-glutaminyl]; Livoletide; AZP 531; AZP531; cyclci DAG(6-13). Grade: ≥95%. CAS No. 1088543-62-7. Molecular formula: C40H63N15O13. Mole weight: 962.02.
BA 1
BA 1 is a potent bombesin receptor subtype 3 (BRS-3; BB3) agonist (IC50 = 2.52 nM), and also acts as a GRPR (BB1) and NMBR (BB2) agonist (IC50 = 0.26 and 1.55 nM, respectively). BA 1 enhances glucose transport in obese and diabetic primary myocytes. BA 1 was shown to stimulate NCI-H1299 lung cancer cell proliferation in vitro. Synonyms: BA 1; BA-1; BA1. CAS No. 183241-31-8. Molecular formula: C57H76N14O11. Mole weight: 1133.32.
Bacampicillin
It is produced by the strain of 6-APA and Ampicillin. Bacampicillin may increase the anticoagulant activities of Acenocoumarol as a prodrug of ampicillin. Uses: A penicillin antibiotic. Synonyms: Bacampicilline; 1'-Ethoxycarbonyloxyethyl-(6-D-alpha-aminophenylacetamido)penicillanate. Grade: ≥95%. CAS No. 50972-17-3. Molecular formula: C21H27N3O7S. Mole weight: 465.52.
Bacimethrin
Bacimethrin is produced by the strain of Bacillus megatheriumy and Streptomyces albus. It has anti-fungal and gram-positive bacteria, negative bacteria activity, and vitamin B1 and B6 can reduce its activity. Synonyms: 4-amino-2-methoxy-5-pyrimidinemethanol; 5-pyrimidinemethanol, 4-amino-2-methoxy-. Grade: ≥98%. CAS No. 3690-12-8. Molecular formula: C6H9N3O2. Mole weight: 155.15.
Bacitracin
Bacitracin is a mixture of related cyclic polypeptides produced by organisms of the licheniformis group of Bacillus subtilis var Tracy, which disrupts both gram positive and gram negative bacteria by interfering with cell wall and peptidoglycan synth. Uses: Topical preparation. Synonyms: Altracin; Ayfivin; Baci-Jel; Baciguent; Bacillichin; Bacilliquin; Bacitek Ointment; Fortracin; Parentracin; Penitracin; Topitracin; Tropitracin; Zutracin. Grade: >98%. CAS No. 1405-87-4. Molecular formula: C65H101N17O16S. Mole weight: 1408.67.
Bacitracin A
Bacitracin A is produced by the strain of Bacillus subtilis and Bac. Licheni formis. The most active and potent compound in standard-grade bacitracin which is comprised of a mixture of several related compounds with different antimicrobial properties. Synonyms: Fortracin; Mycitracin; UNII-DDA3RRX0P7; DDA3RRX0P7. CAS No. 22601-59-8. Molecular formula: C66H103N17O16S. Mole weight: 1422.71.
Bacitracin B1 (acetate)
It is produced by the strain of Bacillus sp. It is a highly purified form of bacitracin B1 and a compound present in standard grade bacitracin. It together with bacitracin B2 is slightly less active than bacitracin A. Synonyms: Bacitracin F, 1-[N-[[2-(1-amino-2-methylbutyl)-4,5-dihydro-4-thiazolyl]carbonyl]-L-leucine]-6-L-valine-; Bacitracin B1a; L-Asparagine, N-[[2-(1-amino-2-methylbutyl)-4,5-dihydro-4-thiazolyl]carbonyl]-L-leucyl-D-a-glutamyl-L-isoleucyl-L-lysyl-D-ornithyl-L-valyl-D-phenylalanyl-L-histidyl-D-a-aspartyl-, cyclic (10,4)-peptide, [4R-[2(1S*,2S*),4R*]]-. Grade: ≥90.0% by HPLC. CAS No. 57762-79-5. Molecular formula: C65H101N17O16S. Mole weight: 1408.66.
Bacitracin F
Bacitracin F is a major Bacitracin analog, a peptide antibiotic used as an inhibitor of protein disulfide isomerase (PDI). It is isolated from Bacillus. Synonyms: Bacitracin EP Impurity E; 4,10-anhydro[N-[[2-[(2S)-2-methyl-1-oxobutyl]-1,3-thiazol-4-yl]carbonyl]-L-leucyl-D-α-glutamyl-L-isoleucyl-Llysyl-D-ornithyl-L-isoleucyl-D-phenylalanyl-L-histidyl-D-α-aspartyl-L-asparagine]. Grade: >95%. CAS No. 22601-63-4. Molecular formula: C66H98N16O17S. Mole weight: 1419.68.
Bactobolin
Bactobolin is produced by the strain of Pseudomonas yoshitomensis. It has the activity of anti-gram-positive bacteria and negative bacteria, and can be used to inhibit experimental tumor. Synonyms: (-)-Bactobolin; Antibiotic BN 183B; Propanamide, 2-amino-N-(3-(dichloromethyl)-3,4,4a,5,6,7-hexahydro-5,6,8-trihydroxy-3-methyl-1-oxo-1H-2-benzopyran-4-yl)-, (3S-(3alpha,4alpha(R*),4abeta,5beta,6alpha))-. CAS No. 72615-20-4. Molecular formula: C14H20Cl2N2O6. Mole weight: 383.22.
Bafilomycin A1
It is produced by the strain of Streptomyces griseus ssp. sulphurus TU 1022 and Str. griseus TU 2437. Bafilomycin A1 is a vacuolar H+-ATPase inhibitor with IC50 of 0.44 nM. It can inhibit the growth of gram-positive bacteria, negative bacteria, fungi, yeast and protozoa, and has the effects of insect killing, nematode killing and immunosuppression. Synonyms: NSC 381866; NSC-381866; NSC381866; Oxacyclohexadeca-3,5,11,13-tetraen-2-one, 8-hydroxy-16-[(1S,2R,3S)-2-hydroxy-1-methyl-3-[(2R,4R,5S,6R)-tetrahydro-2,4-dihydroxy-5-methyl-6-(1-methylethyl)-2H-pyran-2-yl]butyl]-3,15-dimethoxy-5,7,9,11-tetramethyl-, (3Z,5E,7R,8S,9S,11E,13E,15S,16R)-; (3Z,5E,7R,8S,9S,11E,13E,15S,16R)-8-Hydroxy-16-[(1S,2R,3S)-2-hydroxy-1-methyl-3-[(2R,4R,5S,6R)-tetrahydro-2,4-dihydroxy-5-methyl-6-(1-methylethyl)-2H-pyran-2-yl]butyl]-3,15-dimethoxy-5,7,9,11-tetramethyloxacyclohexadeca-3,5,11,13-tetraen-2-one; Hygrolidin, 21-O-de(3-carboxy-1-oxo-2-propenyl)-2-demethyl-2-methoxy-24-methyl-; (-)-Bafilomycin A1; Oxacyclohexadeca-3,5,11,13-tetraen-2-one, 8-hydroxy-16-[2-hydroxy-1-methyl-3-[tetrahydro-2,4-dihydroxy-5-methyl-6-(1-methylethyl)-2H-pyran-2-yl]butyl]-3,15-dimethoxy-5,7,9,11-tetramethyl-, [7R-[3Z,5E,7R*,8S*,9S*,11E,13E,15S*,16R*[1S*,2R*,3S*(2R*,4R*,5S*,6R*)]]]-. Grade: ≥95% by HPLC. CAS No. 88899-55-2. Molecular formula: C35H58O9. Mole weight: 622.83.
Bafilomycin B1
Bafilomycin B1 is produced by the strain of Streptomyces griseus ssp. sulphurus TU 1022 and Str. griseus TU 2437. A member of a potent family of macrocyclic lactones; broadly active against bacteria, fungi, insects, nematodes and protozoans; a potential agent for treating osteoporosis. It can inhibit the growth of gram-positive bacteria, negative bacteria, fungi, yeast and protozoa, and has the effects of insect killing, nematode killing and immunosuppression. Synonyms: Setamycin. Grade: >95% by HPLC. CAS No. 88899-56-3. Molecular formula: C44H65NO13. Mole weight: 815.98.
Bafilomycin D
Bafilomycin D is a macrolide antibiotic produced by Streptomyces. Bafilomycin D is an inhibitor that is more selective than Balifomycin A. Synonyms: Tubaymycin, 3D5. Grade: >99% by HPLC. CAS No. 98813-13-9. Molecular formula: C35H56O8. Mole weight: 604.81.
Bak BH3
Bak BH3, derived from the BH3 domain of Bak, was found to antagonize the protective effects of microinjected Bcl-xL in a-Fas-treated HeLa cells, whereas a mutant Bak BH3 peptide that no longer binds Bcl-xL was inactive. Synonyms: BakBH3; Bak-BH3; H-Gly-Gln-Val-Gly-Arg-Gln-Leu-Ala-Ile-Ile-Gly-Asp-Asp-Ile-Asn-Arg-OH; glycyl-L-glutaminyl-L-valyl-glycyl-L-arginyl-L-glutaminyl-L-leucyl-L-alanyl-L-isoleucyl-L-isoleucyl-glycyl-L-alpha-aspartyl-L-alpha-aspartyl-L-isoleucyl-L-asparagyl-L-arginine. Grade: ≥95%. Molecular formula: C72H125N25O24. Mole weight: 1724.95.
[bAla8]-Neurokinin A (4-10)
An agonist of neurokinin 2 (NK2) receptor. Synonyms: MEN 10210; H-Asp-Ser-Phe-Val-bAla-Leu-Met-NH2; DSFVXLM; L-alpha-aspartyl-L-seryl-L-phenylalanyl-L-valyl-beta-alanyl-L-leucyl-L-methioninamide. Grade: ≥95%. CAS No. 122063-01-8. Molecular formula: C35H56N8O10S. Mole weight: 780.93.
Balanol
It is produced by the strain of Streptomyces sp. Tu 4128. Balanol, a fungal metabolite, is a potent ATP-competitive inhibitor of Protein Kinase C (PKC) and Protein Kinase A (PKA). It is an important target in oncology. Synonyms: 4-(2-Carboxy-6-hydroxybenzoyl)-3,5-dihydroxybenzoic Acid (3R,4R)-Hexahydro-3-[(4-hydroxybenzoyl)amino]-1H-azepin-4-yl Ester; (3R-trans)-Balanol; (-)-Balanol; Azepinostatin; Ophiocordin. Grade: >95%. CAS No. 63590-19-2. Molecular formula: C28H26N2O10. Mole weight: 550.53.
Balixafortide
Balixafortide is a potent and selective antagonist of the chemokine receptor CXCR4. The combination of balixafortide and eribulin was previously granted a fast track designation for the treatment of HER2-negative metastatic breast cancer in patients who have received at least 2 prior lines of chemotherapy in the metastatic setting by the FDA in 2018. Synonyms: POL6326. Grade: >98%. CAS No. 1051366-32-5. Molecular formula: C84H118N24O21S2. Mole weight: 1864.11.
BAM-22P
BAM 22P is a potent endogenous agonist peptide for sensory neuron specific receptor (SNSR) (EC50 = 13 and 16 nM for human SNSR3 and SNSR4, respectively). BAM 22P is also a potent opioid agonist (IC50 = 1.3 nM in guinea pig ileum preparation) displaying opioid- and non-opioid receptor mediated antinociceptive effects in vivo. Synonyms: Bovine adrenal medulla-22P; Bam 22P; H-Tyr-Gly-Gly-Phe-Met-Arg-Arg-Val-Gly-Arg-Pro-Glu-Trp-Trp-Met-Asp-Tyr-Gln-Lys-Arg-Tyr-Gly-OH; L-tyrosyl-glycyl-glycyl-L-phenylalanyl-L-methionyl-L-arginyl-L-arginyl-L-valyl-glycyl-L-arginyl-L-prolyl-L-alpha-glutamyl-L-tryptophyl-L-tryptophyl-L-methionyl-L-alpha-aspartyl-L-tyrosyl-L-glutaminyl-L-lysyl-L-arginyl-L-tyrosyl-glycine. Grade: ≥95%. CAS No. 76622-26-9. Molecular formula: C130H184N38O31S2. Mole weight: 2839.22.
BAM (8-22)
BAM (8-22) is an endogenous peptide agonist for the sensory neuron specific receptor (SNSR) (EC50 = 28 and 14 nM for SNSR3 and SNSR4, respectively). It exhibits spinal analgesic effects by interacting with NMDA receptors. BAM (8-22) displays no affinity for opioid receptors compared to BAM 22. Synonyms: Bovine Adrenal Medulla Peptide (8-22); H-Val-Gly-Arg-Pro-Glu-Trp-Trp-Met-Asp-Tyr-Gln-Lys-Arg-Tyr-Gly-OH; BAM-22P (8-22); L-valyl-glycyl-L-arginyl-L-prolyl-L-alpha-glutamyl-L-tryptophyl-L-tryptophyl-L-methionyl-L-alpha-aspartyl-L-tyrosyl-L-glutaminyl-L-lysyl-L-arginyl-L-tyrosyl-glycine; BAM-15. Grade: ≥95%. CAS No. 412961-36-5. Molecular formula: C91H127N25O23S. Mole weight: 1971.22.
Bambermycin
Bambermycin (flavomycin) is a complex of antibiotics obtained from Streptomyces bambergiensis and Streptomyces ghanaensis used as a food additive for beef cattle, dairy cattle, poultry and swine. The complex consists mainly of moenomycins A and C. Synonyms: Moenomycin complex; Flavomycin. Grade: >95% by HPLC, Moenomycin complex. Mixture of Moenomycin A, Moenomycin A12, Moenomycin C1, Moenomycin C3, Moenomycin C4. CAS No. 11015-37-5. Molecular formula: C69H107N4O35P. Mole weight: 1583.56.
Bardoxolone methyl
Bardoxolone methyl (also known as "RTA 402" and "CDDO-methyl ester") is an orally-available first-in-class synthetic triterpenoid belonging to the antioxidant inflammation modulator (AIM) class. It is the most potent known inducer of the Nrf2 pathway to enter clinical development and works to suppress both oxidative stress and inflammation. Uses: Bardoxolone methyl, also known as rta 402, is a semisynthetic derivative of oleanolic acid that has attracted much attention in the medical community for its potential to treat a variety of chronic diseases, especially chronic kidney disease (ckd). as a member of the antioxidant inflammatory modulator (aim) class of drugs, bardoxolone methyl exerts its therapeutic effects by targeting inflammation. Synonyms: CDDO Methyl ester; CDDOMe; RTA 402; RTA-402; RTA402; TP-155; TP155; TP 155; 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid methyl ester; bardoxolone methyl; CDDO-Me; methyl 2-cyano-3,12-dioxoolean-1,9-dien-28-oate; (4aS,6aR,6bS,8aR,12aS,14bS)-Methyl 11-cyano-2,2,6a,6b,9,9,12a-heptamethyl-10,14-dioxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,12a,14,14a,14b-octadecahydropicene-4a-carboxylate. Grade: ≥ 98.0%. CAS No. 218600-53-4. Molecular formula: C32H43NO4. Mole weight: 505.70.
It is a cyclooctadepsipeptide antibiotic isolated from the entomopathogenic fungi. It is one of the active components of beauveria bassiana biocontrol products. It has insecticidal properties. Synonyms: (-)-Bassianolide; NSC 321804; BASS; cyclo[N(Me)Leu-D-OVal-N(Me)Leu-D-OVal-N(Me)Leu-D-OVal-N(Me)Leu-D-OVal]; cyclo[N-methyl-L-leucyl-N-oxa-D-valyl-N-methyl-L-leucyl-N-oxa-D-valyl-N-methyl-L-leucyl-N-oxa-D-valyl-N-methyl-L-leucyl-N-oxa-D-valyl]. Grade: >95% by HPLC. CAS No. 64763-82-2. Molecular formula: C48H84N4O12. Mole weight: 909.20.
Baumycin C1
Baumycin C1, an impurity of Daunorubicin and Doxorubicin, is an anthracycline antibiotic isolated from Streptomyces coeruleorubidus. Baumycin C1 shows antitumor activity. Synonyms: N-((2S,3S,4S,6R)-6-(((1S,3S)-3-acetyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl)oxy)-3-hydroxy-2-methyltetrahydro-2H-pyran-4-yl)formamide; N-Formyldaunorubicin; NSC 227012; 5,12-Naphthacenedione, 8-acetyl-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-10-((2,3,6-trideoxy-3-(formylamino)-alpha-L-lyxo-hexopyranosyl)oxy)-, (8S-cis)-; (8S,10S)-8-Acetyl-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-10-[(3-(formylamino)-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-5,12-naphthacenedione. Grade: ≥95%. CAS No. 63084-42-4. Molecular formula: C28H29NO11. Mole weight: 555.53.
Bax inhibitor peptide, negative control
A negative control peptide for the Bax inhibitor peptide V5, which inhibits Bax translocation to mitochondria and Bax-mediated apoptosis in vitro. Synonyms: L-isoleucyl-L-prolyl-L-methionyl-L-isoleucyl-L-lysine. Grade: >98%. CAS No. 1315378-74-5. Molecular formula: C28H52N6O6S. Mole weight: 600.82.
Bax inhibitor peptide V5
Bax inhibitor peptide V5, a peptide inhibitor, as a pro-apoptotic member of Bcl-2 family proteins and plays an important role in mitochondria-dependent apoptosis. Uses: A pro-apoptotic member of bcl-2 family proteins. Synonyms: L-Valyl-L-prolyl-L-methionyl-L-leucyl-L-lysine. Grade: ≥97% by HPLC. CAS No. 579492-81-2. Molecular formula: C27H50N6O6S. Mole weight: 586.8.
Bax inhibitor peptide V5 acetate
Bax inhibitor peptide V5 acetate, a Bax-mediated apoptosis inhibitor, is a pro-apoptotic member of Bcl-2 family proteins and plays an important role in mitochondria-dependent apoptosis. It is used in cancer treatment. Synonyms: BIP-V5 acetate; H-Val-Pro-Met-Leu-Lys-OH.CH3CO2H; VPMLK acetate; L-valyl-L-prolyl-L-methionyl-L-leucyl-L-lysine acetic acid. Grade: ≥95%. CAS No. 2760881-58-9. Molecular formula: C29H54N6O8S. Mole weight: 646.85.
BCN-Biotin (exo)
A biotinylation reagent with a BCN moiety for click chemistry. Grade: >95%. Molecular formula: C20H28N2O3S. Mole weight: 376.51.
A biotinylation reagent containing a BCN moiety for click chemistry. Grade: >90%. Molecular formula: C29H46N4O7S. Mole weight: 594.31.
BCN-PEG3-Biotin (exo)
A biotinylation reagent with a BCN moiety for click chemistry. Grade: >90%. Molecular formula: C29H46N4O7S. Mole weight: 594.31.
b-D-Galactose-sp-biotin
b-D-Galactose-sp-biotin, an essential biomolecular compound, serves as a pivotal tool in the realm of biomedical science for combating diverse diseases and disorders. With its distinctive role as a biomarker and labeling agent, this indispensable product finds its application in an array of biochemical and biotechnological domains. It plays a paramount role in facilitating the development of diagnostic apparatus, conducting comprehensive research, and formulating effective medications, specifically targeting galactose metabolism and its associated ailments. Synonyms: Galb-OCH2CH2CH2NH2-spacer-biotin; (3aS,4S,6aR)-N-[6-[[3-(β-D-Galactopyranosyloxy)propyl]amino]-6-oxohexyl]hexahydro-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanamide; 1H-Thieno[3,4-d]imidazole-4-pentanamide, N-[6-[[3-(β-D-galactopyranosyloxy)propyl]amino]-6-oxohexyl]hexahydro-2-oxo-, (3aS,4S,6aR)-. Grade: ≥95% by HNMR. CAS No. 870891-13-7. Molecular formula: C25H44N4O9S. Mole weight: 576.70.
BDS I
BDS I is a reversible Kv3.4 potassium channel blocker (IC50 = 47 nM) and Nav1.7 channel agonist. BDS I potentiates TTX-sensitive sodium currents in rat small dorsal root ganglion neurons. BDS I has potential therapeutic effect on major CNS disorders, such as Alzheimer and Parkinson diseases. Uses: Potential treatment of major cns disorders. Synonyms: Blood depressing substance 1. Grade: >95%. Molecular formula: C210H297N57O56S6. Mole weight: 4708.37.
BE 14106
BE 14106 is produced by the strain of Streptomyces sp. It has weak anti-Pseudomonas aeruginosa activity and inhibition of mixed lymphocyte reaction (MLR) activity. Synonyms: BE-14106; GT-32A; 9,10-Dihydroxy-7,15-dimethyl-20-(2-hexenyl)azacycloeicosa-3,5,7,11,13,15,17-heptaen-2-one. CAS No. 140212-86-8. Molecular formula: C27H37NO3. Mole weight: 423.59.
Beauvericin
Beauvericin is produced by the strain of Streptomyces sp. Ba cyclic depsipeptide isolated from several fungal genera, notably beauveria and fusarium; exhibits broad antifungal, antibacterial, antiprotozoan and insecticidal activities; exhibits ionophoric properties, and inhibits acyl-coa:Cholesterol acyltransferase activity; induces apoptosis by elevating intracellular calcium levels. Synonyms: Cyclo(-D-alpha-hydroxyisovaleryl-N-Me-Phe)3. Grade: >97% by HPLC. CAS No. 26048-05-5. Molecular formula: C45H57N3O9. Mole weight: 783.95.
Beauveriolide I
Beauveriolide I is produced by the strain of Beauveria sp. FO-6979. The effect of I and III can inhibit the formation of Lipid droplet. 10μmol/L can reduce the number and size of the cytolipid droplet in the macrophage but it is not cytotoxic to the macrophages. Synonyms: CHEMBL516093; SCHEMBL15474166. CAS No. 154491-55-1. Molecular formula: C27H41N3O5. Mole weight: 487.63.
Beauveriolide III
Beauveriolide III is produced by the strain of Beauveria sp. FO-6979. The effect of I and III can inhibit the formation of Lipid droplet. 10μmol/L can reduce the number and size of the cytolipid droplet in the macrophage but it is not cytotoxic to the macrophages. Synonyms: CHEMBL409855; SCHEMBL16174055. CAS No. 221111-70-2. Molecular formula: C27H41N3O5. Mole weight: 487.63.
Beinaglutide
Beinaglutide is a recombinant human GLP-1 (rhGLP-1) approved as a novel drug for diabetes treatment. Beinaglutide also has promising effect on obesity. Synonyms: Benaglutide; Glucagon like peptide-i (7-36); BEM-014; H-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-OH. CAS No. 123475-27-4. Molecular formula: C149H225N39O46. Mole weight: 3298.61.
BeKm 1
BeKm 1 is a potent and selective KV11.1 (hERG) channel blocker. CAS No. 524962-01-4. Molecular formula: C174H261N51O52S6. Mole weight: 4091.65.
Bentiromide
Bentiromide is a compound used primarily in medical testing to assess pancreatic exocrine function. It is a synthetic peptide composed of para-aminobenzoic acid (PABA) linked to a dipeptide. When taken orally, bentiromide is broken down by the enzyme chymotrypsin, which is produced by the pancreas. This test is especially useful in diagnosing conditions like chronic pancreatitis, cystic fibrosis, and other disorders that affect pancreatic function. Uses: Diagnostic for pancreatic function. Synonyms: Bz-Tyr-4Abz-OH; N-(N-benzoyl-L-tyrosyl)-4-aminobenzoic acid; 4-[[(2S)-2-(Benzoylamino)-3-(4-hydroxyphenyl)-1-oxopropyl]amino]benzoic acid; Benzoic acid, 4-[[2-(benzoylamino)-3-(4-hydroxyphenyl)-1-oxopropyl]amino]-, (S)-; 4-(N-Benzoyl-L-tyrosyl)aminobenzoic acid; Benzoyltyrosyl-p-aminobenzoic acid; N-Benzoyl-L-tyrosyl-p-aminobenzoate; N-Benzoyl-L-tyrosyl-p-aminobenzoic acid. Grade: ≥95%. CAS No. 37106-97-1. Molecular formula: C23H20N2O5. Mole weight: 404.42.
Benzalkonium Bromide
Benzalkonium Bromide is a cationic surfactant used as a preservative for ophthalmic, nasal and parenteral products. It can be used as a disinfectant and antiseptic, and used to disinfect surgical instruments, skin and wounds. Uses: Benzalkonium bromides are an important class of cationic surfactants. they are used as preservatives for ophthalmic, nasal and parenteral products and they are also used as a topical antiseptic and medical equipment disinfectant. Synonyms: Benzenemethanaminium, N-dodecyl-N,N-dimethyl-, bromide (1:1); Ammonium, benzyldodecyldimethyl-, bromide; Benzyldodecyldimethylammonium bromide; AACL 6; Amonyl BR 1244; Bacfor BL; Benzododecinium bromide; Benzyldimethyldodecylammonium bromide; Benzyldimethyllaurylammonium bromide; Benzyllauryldimethylammonium bromide; Cequartyl 50; Dimethylbenzyldodecylammonium bromide; Dimethylbenzyllaurylammonium bromide; Dimethyldodecylbenzylammonium bromide; Dimethyllaurylbenzylammonium bromide; Dodecylbenzyldimethylammonium bromide; Dodecyldimethylbenzylammonium bromide; Lauralkonium bromide; Lauryldimethylbenzylammonium bromide; N,N-Dimethyl-N-benzyldodecylammonium bromide; N,N-Dimethyl-N-dodecylbenzylammonium bromide; N-Benzyl-N,N-dimethyl-N-dodecylammonium bromide; Sinnoquat BL 80; Sinnoquat BL 95; Sterinol; Xinjieermie. Grade: >97.0%(T). CAS No. 7281-4-1. Molecular formula: C21H38BrN. Mole weight: 384.44.
Benzalkonium chloride
A synthetic quaternary ammonium salt used as a cationic surfactant and preservative in cosmetics and disinfectants. Synonyms: Alkylbenzyldimethylammonium chloride; Quaternary ammonium compounds, alkylbenzyldimethyl, chlorides. Grade: 98%. CAS No. 8001-54-5. Molecular formula: C11H18ClN(C2H4)n.
BENZALKONIUM SACCHARINATE
BENZALKONIUM SACCHARINATE. Grade: 95%. CAS No. 39387-42-3.
Benzathine penicilline
Benzathine penicilline is an antibiotic useful for the treatment of a number of bacterial infections, which is also known as benzathine penicillin G. It has bacteriostatic and bacteriocidal actions against most Gram-positive bacteria and Gram-negative cocci. Uses: Anti-bacterial agents. Synonyms: Debecillin; Pendepon; Penduran. Grade: >98%. CAS No. 1538-09-6. Molecular formula: C48H56N6O8S2. Mole weight: 909.12.
Benzene, diethenyl-, polymer with ethenylbenzene and ethenylethylbenzene, aminomethylated, chloromethane-quaternized, hydroxide
Benzene, diethenyl-, polymer with ethenylbenzene and ethenylethylbenzene, aminomethylated, chloromethane-quaternized, hydroxide. CAS No. 113114-06-0.
Benzene, diethenyl-, polymer with ethenylbenzene, chloromethylated,2-(dimethylamino)ethanol-quaterni
Benzene, diethenyl-, polymer with ethenylbenzene, chloromethylated,2-(dimethylamino)ethanol-quaterni. Grade: 95%. CAS No. 68441-27-0. Molecular formula: (C10H10?C8H8?C4H11NO)x. Mole weight: 323.47200.
Benzomalvin A
It is produced by the strain of Penicillum sp. Benzomalvin A was isolated as an active inhibitor of substance P binding to mammalian neurokinin NK1 receptors. Benzomalvin A is a fungal metabolite produced by Penicillium. It inhibits yeast α-glucosidase in vitro with IC50 of 383.2 μM. Benzomalvin A also acts as an antagonist of neurokinin-1 (NK1) receptors, inhibiting binding of substance P to guinea pig, rat, and human NK1 (Kis = 12, 42, and 43 μM, respectively). Synonyms: (-)-Benzomalvin A; Enzomalvin-A. Grade: ≥95%. CAS No. 157047-96-6. Molecular formula: C24H19N3O2. Mole weight: 381.43.
Benzomalvin B
It is produced by the strain of Penicillum sp. Benzomalvin B was isolated as an active inhibitor of substance P binding to mammalian neurokinin NK1 receptors. Benzomalvin B is a fungal metabolite produced by Penicillium. It acts as an antagonist of neurokinin-1 (NK1) receptors, inhibiting binding of substance P by 24% in vitro when used at a concentration of 100 μg/ml. Synonyms: (-)-Benzomalvin B; Enzomalvin-B. Grade: ≥95%. CAS No. 157047-97-7. Molecular formula: C24H17N3O2. Mole weight: 379.41.
Benzomalvin C
Benzomalvin C is produced by the strain of Penicillum sp. It is a neurokinin NK1 receptor antagonist and IDO inhibitor. Synonyms: 6'-methyl-3-phenyl-13'h-spiro[oxirane-2,7'-quinazolino[3,2-a][1,4]benzodiazepine]-5',13'(6'h)-dione; GK3542; GK 3542; GK-3542; benzomalvin C. Grade: >98%. CAS No. 157047-98-8. Molecular formula: C24H17N3O3. Mole weight: 395.41.
Benzyl 2,2,2-trichloroacetimidate
Benzyl 2,2,2-Trichloroacetimidate is a reactant used in the synthesis of Allosamidin; an insect chitinase inhibitor. Synonyms: 2,2,2-Trichloroethanimidic Acid Phenylmethyl Ester; 2,2,2-Trichloroacetimidic Acid Benzyl Ester; Benzyl Trichloroacetimidate; O-Benzyl 2,2,2-Trichloroacetimidate; Benzyltrichloroacetimidate; Trichloroacetimidic Acid Benzyl Ester; Ethanimidic acid, 2,2,2-trichloro-, phenylmethyl ester. Grade: > 98 %. CAS No. 81927-55-1. Molecular formula: C9H8Cl3NO. Mole weight: 252.52.
Benzyl 2,4-Difluorobenzoate
Benzyl 2,4-Difluorobenzoate (CAS# 473691-24-6 ) is a useful research chemical. Synonyms: 2,4-difluorobenzoic acid (phenylmethyl) ester; benzyl 2,4-difluorobenzoate. CAS No. 473691-24-6. Molecular formula: C14H10F2O2. Mole weight: 248.22.
Benzyl 2-(Benzyloxy)-3-bromobenzoate is an intermediate formed in the synthesis of 3-[4-(2-Pyridylsulfamoyl)phenyl] Sulfasalazine (P995810), an impurity of Sulfasalazine (S699084), an anti-inflammatory (gastrointestinal). Sulfasalazine has been used in granulomatous colitis. Synonyms: Benzyl 2-(benzyloxy)-3-bromobenzoate. Molecular formula: C21H17BrO3. Mole weight: 397.26.
Benzyl 2-(Benzylthio)-3-methylbenzoate
Benzyl 2-(Benzylthio)-3-methylbenzoate is an intermediate for the synthesis of Triflusulfuron (T782005), which is an anilinopyrimidine fungicide which have been used in the management of fungal diseases in strawberries. CAS No. 2807778-68-1. Molecular formula: C22H20O2S. Mole weight: 348.46.
Benzyl 2-(Chlorosulfonyl)-3-methylbenzoate
Benzyl 2-(Chlorosulfonyl)-3-methylbenzoate is an intermediate for the synthesis of Triflusulfuron (T782005), which is an anilinopyrimidine fungicide which have been used in the management of fungal diseases in strawberries. CAS No. 2802916-33-0. Molecular formula: C15H13ClO4S. Mole weight: 324.78.
Benzyl 2-Fluoro-4-morpholinobenzoate
Benzyl 2-Fluoro-4-morpholinobenzoate (CAS# 1272756-24-7 ) is a useful research chemical. Synonyms: 2-fluoro-4-(4-morpholinyl)benzoic acid (phenylmethyl) ester; benzyl 2-fluoro-4-morpholin-4-ylbenzoate. CAS No. 1272756-24-7. Molecular formula: C18H18FNO3. Mole weight: 315.34.
Benzyl 2-hydroxy-6-(β-glucosyloxy)benzoate is a natural compound isolated from the herbs of Endlicheria dysodantha. Synonyms: benzyl 2-hydroxy-6-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxybenzoate. Grade: 98.5%. CAS No. 403857-21-6. Molecular formula: C20H22O9. Mole weight: 406.38.
Benzyl 2-hydroxy-6-methoxybenzoate
Benzyl 2-hydroxy-6-methoxybenzoate has the strongest antifungal activity, with IC50s of 25-26 μg/mL for both fungal strains. Synonyms: 2-Hydroxy-6-methoxybenzoic acid benzyl ester; Benzoic acid, 2-hydroxy-6-methoxy-, phenylmethyl ester; benzoic acid, 2-hydroxy-6-methoxy-, benzyl ester. CAS No. 24474-71-3. Molecular formula: C15H14O4. Mole weight: 258.27.