BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Aldehydo-D-glucose phthalazin-1-yl hydrazone | Aldehydo-D-glucose phthalazin-1-yl hydrazone is an extensively employed chemical compound in the biomedical industry, exhibiting potential for studying diverse ailments such as cancer and diabetes. Molecular formula: C14H18N4O5. Mole weight: 322.32. |  |
| Aldehydo-D-glucose Phthalazin-1-ylhydrazone | Aldehydo-D-glucose Phthalazin-1-ylhydrazone is a carbohydrate derivative of hydrazinophthalazine with anti-inflammatory activity. Synonyms: 1-(2-D-Glucopyranosylhydrazino)phthalazine; 1-Deoxy-1-[2-(1-phthalazinyl)hydrazinyl]-D-glucopyranose. Grades: 95%. CAS No. 881180-23-0. Molecular formula: C14H18N4O5. Mole weight: 322.32. | |
| Aldgamycin F | It is produced by the strain of Streptomyces lavendulae and Str. avidinii. The anti-gram-positive bacteria activity of G was stronger than that of F, and the anti-Staphylococcus aureus activity was similar to that of xiramycin. CAS No. 55141-41-8. Molecular formula: C37H56O16. Mole weight: 756.83. | |
| Aldgamycin G | It is produced by the strain of Streptomyces lavendulae and Str. avidinii. The anti-gram-positive bacteria activity of G was stronger than that of F, and the anti-Staphylococcus aureus activity was similar to that of xiramycin. Synonyms: 8-Deoxyaldgamycin F; Aldgamycin G; Aldgamycin F, 8-deoxy-; LS-16283; (6Z,14Z)-2-(((5-hydroxy-3,4-dimethoxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)methyl)-9-((6-hydroxy-4,9-dimethyl-2-oxo-1,3,8-trioxaspiro[4.5]decan-7-yl)oxy)-3,8,10,12-tetramethyl-4,17-dioxabicyclo[14.1.0]heptadeca-6,14-diene-5,13-dione; 1,3,8-Trioxaspiro[4.5]decane, aldgamycin F deriv.; 4,17-Dioxabicyclo[14.1.0]heptadecane, aldgamycin F deriv. Grades: 95%. CAS No. 107745-56-2. Molecular formula: C37H56O15. Mole weight: 740.83. | |
| Aldicarb sulfone | Aldicarb Sulfone is an analog of Aldicarb detected in agricultural products as pesticide residue. Synonyms: Temik sulfone. Grades: >98%. CAS No. 1646-88-4. Molecular formula: C7H14N2O4S. Mole weight: 222.26. | |
| Aldioxa | Aldioxa is a gastrointestinal agent that improves delayed gastric emptying. Synonyms: Isalon; Dihydroxyaluminum allantoinate; Chlokale; Peptilate; Ascomp; [4-(carbamoylamino)-5-oxo-1,4-dihydroimidazol-2-yl]oxyaluminum dihydrate. CAS No. 5579-81-7. Molecular formula: C4H9AlN4O5. Mole weight: 220.121. | |
| Aldosterone | An adrenocortical steroid which exerts regulatory influence on metabolism of electrolytes and water. Synonyms: (11β)-11,21-Dihydroxy-3,20-dioxopregn-4-en-18-al; 11β,21-Dihydroxypregn-4-ene-3,18,20-trione; 18-Formyl-11β,21-dihydroxy-4-pregnene-3,20-dione; 18-Oxocorticosterone; Electrocortin; Aldocortin; Aldocorten. Grades: > 95%. CAS No. 52-39-1. Molecular formula: C21H28O5. Mole weight: 360.45. | |
| A-Leb-heptasaccharide | A-Leb-heptasaccharide is a biomedical compound used in the research of Leber congenital amaurosis (LCA), a rare inherited retinal degenerative disease. Molecular formula: C46H78N2O34. Mole weight: 1203.10. | |
| Alectinib | Alectinib, marketed as Alecensa, is an oral drug that blocks the activity of anaplastic lymphoma kinase (ALK) and is used to treat non-small-cell lung cancer (NSCLC). Alectinib has a low potential for interactions. While it is metabolised by the liver enzyme CYP3A4, and blockers of this enzyme accordingly increase its concentrations in the body, they also decrease concentrations of the active metabolite M4, resulting in only a small overall effect. Conversely, CYP3A4 inducers decrease alectinib concentrations and increase M4 concentrations. Interactions via other CYP enzymes and transporter proteins cannot be excluded but are unlikely to be of clinical significance. Synonyms: CH-5424802; CH5424802; CH 5424802; AF-802; RG-7853; RO5424802. Grades: ≥95%. CAS No. 1256580-46-7. Molecular formula: C30H34N4O2. Mole weight: 482.62. | |
| Alectorialin | Synonyms: Benzoic acid, 3-formyl-2,4-dihydroxy-6-methyl-, (3,5-dihydroxy-4-methylphenyl)methyl ester; 3-Formyl-2,4-dihydroxy-6-methyl-benzoic acid 3,5-dihydroxy-4-methyl-benzyl ester; 3,5-dihydroxy-4-methylbenzyl 3-formyl-2,4-dihydroxy-6-methylbenzoate. CAS No. 55483-02-8. Molecular formula: C17H16O7. Mole weight: 332.30. | |
| Alectoronic acid | Synonyms: 2,5,11-trihydroxy-9-(2-oxoheptyl)-2-pentyl-1,2-dihydro-4H,8H-benzo[6,7][1,4]dioxepino[2,3-f]isochromene-4,8-dione; 4H,8H-[2]Benzopyrano[5,6-b][1,4]benzodioxepin-4,8-dione, 1,2-dihydro-2,5,11-trihydroxy-9-(2-oxoheptyl)-2-pentyl-. CAS No. 54226-87-8. Molecular formula: C28H32O9. Mole weight: 512.55. | |
| Aleglitazar | Aleglitazar is a potent dual agonist of peroxisome proliferator-activated receptor (PPAR) α/&gamma. Synonyms: RO-0728804; RO 0728804; RO0728804; RG-1439; R-1439; R 1439; R1439; Aleglitazar. Grades: >98%. CAS No. 475479-34-6. Molecular formula: C24H23NO5S. Mole weight: 437.51. | |
| Alemtuzumab | Cas No. 216503-57-0. | |
| Alendronate sodium trihydrate | Alendronate, a nitrogen-containing bisphosphonate, is a potent inhibitor of bone resorption used for the treatment and prevention of osteoporosis. Synonyms: G-704650, MK-217; G 704650, MK 217; G704650, MK217. Grades: >98%. CAS No. 121268-17-5. Molecular formula: C4H13NO7P2.3H2O.Na. Mole weight: 326.13. | |
| aleplasinin | Aleplasinin is a selective and potent inhibitor of PAI-1 (Plasminogen activator inhibitor-1). It has been used in the treatment of Alzheimer's disease. Synonyms: PAZ-417; PAZ 417; PAZ417. Grades: 95%. CAS No. 481629-87-2. Molecular formula: C28H27NO3. Mole weight: 425.52. | |
| Aleurodiscal | It is produced by the strain of Aleurodiscus mirabilis. At very low concentrations, Mucor Mie-Hei mycelia were abnormally divergent. Synonyms: Cyclopenta(4,5)cyclooct(1,2-f)indene-6-carboxaldehyde, 1,2,3,3a,4,6a,7,7a,8,9,10,10a,11,11a-tetradecahydro-10-(1-methylethyl)-3,7a,12-trimethyl-2-(beta-D-xylopyranosyloxy)-, (2S-(2-alpha,3-beta,3a-beta,6a-alpha,7a-alpha,10-beta,10a-beta,11a-beta))-. Grades: 95%. CAS No. 122535-46-0. Molecular formula: C30H46O6. Mole weight: 502.68. | |
| Alexamorelin Met 1 | Alexamorelin Met 1 is a metabolite of Alexamorelin. The heptapeptide Ala-His-D-2-methyl-Trp-Ala-Trp-D-Phe-Lys-NH2 (Alexamorelin) is a synthetic molecule that inhibits the secretagogue binding of growth hormone in vitro. Synonyms: (D-Mrp)-Ala-Trp-(D-Phe); d-Mrp-AW-d-Phe. Grades: ≥95%. Molecular formula: C35H38N6O5. Mole weight: 622.73. | |
| Alexidine dihydrochloride | Alexidine dihydrochloride is a potent and selective protein tyrosine phosphatase localized to the mitochondrion 1(PTPMT1) inhibitor with IC50 value of 1.08 μM in vitro. It induces apoptosis in cancer cell lines with ED50 value of 1.8-2.6 μM. It is an alkyl bis(biguanide) antiseptic and has been used in mouthwashes to eliminate plaque forming microorganisms. It binds to lipopolysaccharide and lipoteichoic acid, and inhibits fungal phospholipase B with IC50 value of 250 nM. It stimulates increased insulin secretion by isolated rat pancreatic islets and displays antitcancer properties in FaDu cells. It has antibacterial, antiplaque properties against streptococcus mutans, actinomyces naesludii and actinomyces ciscosus. Synonyms: 2,4,11,13-Tetraazatetradecanediimidamide, N1,N14-bis(2-ethylhexyl)-3,12-diimino-, hydrochloride (1:2); 2,4,11,13-Tetraazatetradecanediimidamide, N,N''-bis(2-ethylhexyl)-3,12-diimino-, dihydrochloride; Biguanide, 1,1'-hexamethylenebis[5-(2-ethylhexyl)-, dihydrochloride; 1,6-Bis(2-ethylhexylbiguanido)hexane dihydrochloride; Alexidine hydrochloride; Hexamethylenebis(2-ethylhexyl)biguanide dihydrochloride. Grades: >98%. CAS No. 1715-30-6. Molecular formula: C26H58N10Cl2. Mole weight: 581.71. | |
| alfa1 , alfa1, alfa3, alfa3-Tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-1,3-Benzenediacetamide) | Anastrozole Impurity. Synonyms: α1 , α1, α3, α3-Tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-1,3-Benzenediacetamide). Grades: > 95%. CAS No. 120512-04-1. Molecular formula: C17H23N5O2. Mole weight: 329.41. | |
| alfa1 , alfa1, alfa3, alfa3-Tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-1,3-Benzenediacetic acid | Anastrozole Impurity. Synonyms: α1 , α1, α3, α3-Tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-1,3-Benzenediacetic acid. Grades: > 95%. CAS No. 1338800-81-9. Molecular formula: C17H21N3O4. Mole weight: 331.37. | |
| alfa-Amyrenone | Amyrenone. Synonyms: Urs-12-en-3-one. Grades: > 95%. CAS No. 638-96-0. Molecular formula: C30H48O. Mole weight: 424.72. | |
| alfa-Amyrin | Cas No. 638-95-9. | |
| Alfacalcidol | A synthetic analog of Calcitiol (the hormonal form of vitamin D3), which shows identical potency with respect to stimulation of intestinal calcium absorption and bone mineral mobilization. Vitamin D source. Synonyms: 1-Hydroxycholecalciferol; Alfarol; EinsAlpha; Alpha-Calcidol; One-Alpha; (1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-7a-methyl-1-[(2R)-6-methylheptan-2-yl]-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,3-diol. Grades: >98%. CAS No. 41294-56-8. Molecular formula: C27H44O2. Mole weight: 400.65. | |
| Alfacalcidol-[d6] | Alfacalcidol-[d6], is the labelled analogue of Alfacalcidol. Alfacalcidol is an active metabolite of Vitamin D, which performs important functions in regulation of the calcium balance and the bone metabolism. Synonyms: 1a Hydroxyvitamin D3-d6 (26,26,26,27,27,27-d6); Alfacalcidol-D6. CAS No. 1641940-94-4. Molecular formula: C27H38D6O2. Mole weight: 406.67. | |
| Alfacalcidol-[d7] | Labelled Alfacalcidol, a synthetic analog of Calcitiol (the hormonal form of vitamin D3), which shows identical potency with respect to stimulation of intestinal calcium absorption and bone mineral mobilization. Vitamin D source. Synonyms: 5-[(2E)-2-[(1R,3aS,7aR)-1-[(1R)-1,5-Dimethylhexyl]octahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-4-methylene-1,3-cyclohexanediol-d7; 1-α-Hydroxycholecalciferol-d7; 1-α-Hydroxyvitamin D3-d7; Alpharol-d7; Alpha D3-d7; Etalpha-d7; Oxydevit-d7. Grades: > 98%. CAS No. 41294-56-8. Molecular formula: C27H37D7O2. Mole weight: 407.68. | |
| Alfacalcidol Impurity A | Cas No. 65445-14-9. | |
| Alfacalcidol Impurity B | Cas No. 63181-13-5. | |
| Alfadolone | Alfadolone, a synthetic steroid hormone, is an effective anti-inflammatory agent that relieves pain and inflammation associated with diseases like arthritis. Further, it is increasingly employed for treating autoimmune disorders like lupus and multiple sclerosis. The mechanism of action of alfadolone involves hampering the production of bodily chemicals responsible for inflammation. Synonyms: Pregnane-11,20-dione, 3,21-dihydroxy-, (3alpha,5alpha)-. Grades: 95%. CAS No. 14107-37-0. Molecular formula: C21H32O4. Mole weight: 348.5. | |
| alfa-Keto-Delta-(NG,NG-Dimethylguanidino)valenic Acid | Intermediate. Synonyms: 5-[[(DiMethylaMino)iMinoMethyl]aMino]-2-oxopentanoic Acid. Grades: > 95%. CAS No. 107347-90-0. Molecular formula: C8H15N3O3. Mole weight: 201.23. | |
| a-L-Fucose-1-phosphate | a-L-Fucose-1-phosphate is an indispensable biochemical compound prevalent in the biomedical industry orchestrating the research and development of glycans and glycoconjugates, paramount for regulating cell signaling and immune response dynamics. | |
| a-L-Fucose-1-phosphate bis(cyclohexylammonium) salt | A paramount constituent in the field of biomedicine, a-L-Fucose-1-phosphate bis(cyclohexylammonium) salt serves as a pivotal factor in the production and analysis of enzymes related to carbohydrate metabolism. Its crucial role further extends to research on liver glycogen storage diseases, as well as in the treatment of select forms of malignancy. Indeed, this reagent proves itself to be a fundamental cornerstone in contemporary biomedical research. Synonyms: α-L-Fucose-1-phosphate (cyclohexylammonium salt); 6-Deoxy-α-L-Galactopyranose 1-(Dihydrogen Phosphate) Cyclohexanamine (1:2); α-L-Fucopyranose 1-(Dihydrogen Phosphate) Di(cyclohexylammonium) Salt; α-L-Fucopyranosyl 1-Phosphate Di(cyclohexylammonium) Salt; α-L-Fucopyranosyl Phosphate Di(cyclohexylammonium) Salt. Grades: ≥98%. CAS No. 24333-03-7. Molecular formula: C6H13O8P.2C6H13N. Mole weight: 442.48. | |
| a-L-Fucosidase kits | | |
| Alfuzosin HCl | Alfuzosin HCl is an alpha1 receptor antagonist used to treat benign prostatic hyperplasia (BPH). Synonyms: (RS)-N-[3-[ (4-Amino-6, 7-dimethoxyquinazolin-2-yl) (methyl)amino]propyl]tetrahydrofuran-2-carboxamide hydrochloride. Grades: >98%. CAS No. 81403-68-1. Molecular formula: C19H28ClN5O4. Mole weight: 425.91. | |
| Alfuzosin Impurity 1 | An impurity of Alfuzosin. Synonyms: 6,7-dimethoxy-N,N-dimethyl-quinazoline-2,4-diamine. Grades: > 95%. CAS No. 19216-68-3. Molecular formula: C12H16N4O2. Mole weight: 248.29. | |
| Alfuzosin Impurity A | An impurity of Alfuzosin. Synonyms: Alfuzosin Tetradehydro Impurity ; Alfuzosin USP RC A. Grades: > 95%. CAS No. 98902-29-5. Molecular formula: C19H23N5O4. HCl. Mole weight: 421.88. | |
| Alfuzosin Impurity C | An impurity of Alfuzosin. Synonyms: (RS)-N-[3-[(4-Amino-6,7-dimethoxyquinazolin-2-yl)amino]propyl]-N-methyltetrahydrofuran-2-carboxamide hydrochloride. Grades: > 95%. CAS No. 72104-34-8. Molecular formula: C19H27N5O4. Mole weight: 389.46. | |
| Alfuzosin Impurity D | An impurity of Alfuzosin. Synonyms: Alfuzosin Aminopropyl Impurity ; Alfuzosin USP RC D. Grades: > 95%. CAS No. 76362-29-3. Molecular formula: C14H21N5O2. Mole weight: 291.36. | |
| Alfuzosin Impurity E HCl | An impurity of Alfuzosin. Synonyms: N-[3-[(4-Amino-6,7-dimethoxyquinazolin-2-yl)(methyl)amino]propyl]formamide hydrochloride. Grades: > 95%. CAS No. 1026411-59-5. Molecular formula: C15H21N5O3. HCl. Mole weight: 319.37 36.46. | |
| a-L-Galactose-1-phosphate dipotassium salt | a-L-Galactose-1-phosphate dipotassium salt is a crucial compound playing a significant role in studying enzymes involved in the Leloir pathway, such as galactose-1-phosphate-uridyltransferase. This salt is employed in the research of potential drugs for studying galactosemia, a metabolic disorder caused by the deficiency of aforementioned enzymes. Synonyms: Dipotassium;[(2S,3S,4R,5S,6S)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] phosphate. Grades: ≥ 99%. CAS No. 262856-84-8. Molecular formula: C6H11K2O9P. Mole weight: 336.33. | |
| a-L-galactose-1-phosphate disodium salt | a-L-galactose-1-phosphate disodium salt, a highly significant compound in the realm of biomedicine, exhibits immense potential for therapeutic application in diverse metabolic disorders. It serves as a pivotal precursor for sphingolipid synthesis, thereby facilitating the effective management of afflictions such as Gaucher disease and Farber disease. Due to its indispensable involvement in enzymatic reactions, a-L-galactose-1-phosphate disodium salt harbors substantial promise for the forefront of novel drug advancement within the biomedical industry. Synonyms: β-L-Galactopyranose, 1-(dihydrogen phosphate)?, disodium salt. CAS No. 210100-25-7. Molecular formula: C6H13O9P.2Na. Mole weight: 306.177. | |
| Algestone | A pregnane steroid, its acetonide is used as anti-inflammatory drug (topical) and combination with enanthate as injectable contraceptive. Uses: Progestins. Synonyms: (16α)-16,17-Dihydroxy-pregn-4-ene-3,20-dione; 16α,17-Dihydroxyprogesterone; 4-Pregnen-16α,17α-diol-3,20-dione; Alfasone; Alphasone. Grades: > 95%. CAS No. 595-77-7. Molecular formula: C21H30O4. Mole weight: 346.47. | |
| Algestone Acetonide | A steroidal progestin used as a contraceptive drug. Synonyms: 16alpha,17-Isopropylidendioxy-4-pregnen-3,20-dion; 16alpha,17-(Isopropylidenedioxy)pregn-4-ene-3,20-dione. Grades: > 95%. CAS No. 4968-9-6. Molecular formula: C24H34O4. Mole weight: 386.54. | |
| Algestone Acetophenide | Algestone Acetophenide is a progestational steroid that has been shown to increase the proteins in milk and serum in goats and decrease the weight gain of kids. Uses: Contraceptives, oral, synthetic. Synonyms: Alphasone Acetophenide; Deladroxone; Dihydroxyprogesterone Acetophenide; Droxone; Neolutin Depositum; 2H-Naphth[1',2':6,7]indeno[1,2-d][1,3]dioxole, Pregn-4-ene-3,20-dione derivative; [16α(R)]-16,17-[(1-Phenylethylidene)bis(oxy)]-pregn-4-ene-3,20-dione. Grades: > 95%. CAS No. 24356-94-3. Molecular formula: C29H36O4. Mole weight: 448.6. | |
| Alginic acid | In tablet and capsule formulations, alginic acid is used as a binder and disintegrating agent. Alginic acid is widely used as a thickener and suspension agent in various pastes, creams and gels. It is also used as a stabilizer for oil-in-water emulsions and as an antacid in therapy. Synonyms: Acidum alginicum; E400; Kelacid; L-gulo-D-mannoglycuronan; polymannuronic acid; Protacid; Satialgine H8. CAS No. 9005-32-7. Molecular formula: (C6H8O6)n. Mole weight: 194.139. | |
| Alginic Acid Calcium Salt | Calcium alginate has been used in pharmaceutical formulations as a disintegrating agent in tablets. Calcium alginate is also used as an emulsifier, stabilizer and thickener. Synonyms: Calcium Alginate; CA33; calcium polymannuronate; Calginate; E404; Kaltostat. Grades: 96%. CAS No. 9005-35-0. Molecular formula: [(C6H7O6)2Ca]n. Mole weight: 398.316680 []. | |
| Alibendol | Alibendol is an antispasmodic,choleretic, and cholekinetic. Synonyms: EB 1856; EB1856; EB-1856. Grades: >98%. CAS No. 26750-81-2. Molecular formula: C13H17NO4. Mole weight: 251.28. | |
| Alimemazine-[d6] | Alimemazine-[d6] is a deuterium labelled Alimemazine, which is an antihistamine. Synonyms: β-Methyl-(N,N-Dimethyl-d6)-10H-phenothiazine-10-propanamine Tartrate; 10-(2-Methyl-3-(dimethyl-d6)aminopropyl)phenothiazine Tartrate; 10-[3-[(Dimethyl-d6)amino]-2-methylpropyl]phenothiazine Tartrate; (+/-)-Alimemazine-d6 Tartrate; Panectyl-d6; Repeltin-d6; Temaril-d6; Temaril 16-d6; Theralene-d6; Vallergan-d6; Vanectyl-d6; NSC 17475-d6. Grades: >98%. CAS No. 1346603-88-0. Molecular formula: C18H16D6N2S. Mole weight: 304.48. | |
| Alimemazine Impurity A | An impurity of Trimetazidine. Trimetazidine is a drug for angina pectoris. Synonyms: Trimeprazine Sulfoxide. Molecular formula: C18H22N2OS. Mole weight: 314.45. | |
| Alipamide | Alipamide is a bio-active chemical with a sequence-specific threading tetra-intercalator with an extremely slow dissociation rate constant. Uses: A bio-active chemical. Synonyms: Alipamide;Alipamidum; CI-546; CN 38474; CN-38,474; D-1721; D 1721; D1721; UNII-PE8925K9EY; 4-Chloro-N',N'-dimethyl-3-sulfamoylbenzohydrazide;Alipamid;CI 546; 2-chloro-5- (dimethylaminocarbamoyl) benzenesulfonamide. Grades: ≥98%. CAS No. 3184-59-6. Molecular formula: C9H12CLN3O3S. Mole weight: 277.03. | |
| Alisamycin | It is produced by the strain of Streptomyces actuosus (Str. sp. Y-8831582). It has anti-gram-positive bacteria, Candida and other fungi activity, and also has weak inhibition of L1210 leukemia cell activity. Synonyms: 2,4,6-Heptatrienamide, 7-(4-((5-cyclohexyl-1-oxo-2,4-pentadienyl)amino)-2-hydroxy-5-oxo-7-oxabicyclo(4.1.0)hept-3-en-2-yl)-N-(2-hydroxy-5-oxo-1-cyclopenten-1-yl)-; 2,4,6-Heptatrienamide,7-[(1S,2R,6R)-4-[[(2E,4E)-5-cyclohexyl-1-oxo-2,4-pentadienyl]amino]-2-hydroxy-5-oxo-7-oxabicyclo[4.1.0]hept-3-en-2-yl]-N-(2-hydroxy-5-oxo-1-cyclopenten-1-yl)-,(2E,4E,6E)-(9CI); 7-Oxabicyclo[4.1.0]heptane, 2,4,6-heptatrienamidederiv.; (-)-Alisamycin. Grades: 95%. CAS No. 136398-54-4. Molecular formula: C29H32N2O7. Mole weight: 520.57. | |
| Alisertib | MLN8237 is a second-generation, orally bioavailable, highly selective small molecule inhibitor of the serine/threonine protein kinase Aurora A kinase with potential antineoplastic activity. Aurora kinase inhibitor MLN8237 binds to and inhibits Aurora A kinase, which may result in disruption of the assembly of the mitotic spindle apparatus, disruption of chromosome segregation, and inhibition of cell proliferation. Synonyms: MLN8237; MLN-8237; MLN 8237; alisertib. Benzoic acid, 4-[[9-chloro-7-(2-fluoro-6-methoxyphenyl)-5H-pyrimido[5,4-d][2]benzazepin-2-yl]amino]-2-methoxy-. Grades: 0.98. CAS No. 1028486-01-2. Molecular formula: C27H20ClFN4O4. Mole weight: 518.9. | |
| Aliskiren | Aliskiren hemifumarate appears to bind to both the hydrophobic S1/S3-binding pocket and to a large, distinct subpocket that extends from the S3-binding site towards the hydrophobic core of renin. Oral bioavailability of Aliskiren hemifumarate is 2.4% in rats, 16% in marmosets and about 2.5% in humans. Aliskiren hemifumarate (< 10 mg/kg, oral) inhibits plasma renin activity and lowers blood pressure in sodium-depleted marmosets.Once-daily oral treatment with Aliskiren hemifumarate lowers blood pressure effectively, with a safety and tolerability profile, in patients with mild-to-moderate hypertension. Uses: Antihypertensive agent; renin; antagonists and inhibitors. Synonyms: CGP 60536; CGP60536B; Rasilez; SPP 100; Tekturna. Grades:>98%. CAS No. 173334-57-1. Molecular formula: C30H53N3O6. Mole weight: 551.76. | |
| Aliskiren Acid Impurity | An impurity of Aliskiren. Synonyms: Aliskiren Carboxylic Acid. Grades: > 95%. CAS No. 173400-13-0. Molecular formula: C30H52N2O7. Mole weight: 552.76. | |
| Aliskiren hemifumarate | Aliskiren is a direct renin inhibitor used for the treatment of essential hypertension. Synonyms: (αS,γS,δS,zS)-δ-Amino-N-(3-amino-2,2-dimethyl-3-oxopropyl)-γ-hydroxy-4-methoxy-3-(3-methoxypropoxy)-α,z-bis(1-methylethyl)benzeno-4-hydroxy-2-isopropyl-7-[4-methoxy-3-(3-methoxy-propoxy)-benzyl]-8-methyl-nonaoyl-2-methyl-propyl)-amide hemifumarate. Grades: 99%. CAS No. 173334-58-2. Molecular formula: C30H53N3O6·1/2C4H4O4. Mole weight: 1219.6. | |
| Aliskiren Hemifumarate (SSSRisomer) Impurity | An impurity of Aliskiren. Synonyms: (αS,γS,δS,ζR)-δ-Amino-N-(3-amino-2,2-dimethyl-3-oxopropyl)-γ-hydroxy-4-methoxy-3-(3-methoxypropoxy)-α,ζ-bis(1-methylethyl)benzeneoctanamide (2E)-2-Butenedioate (2:1). Grades: > 95%. CAS No. 1630036-82-6. Molecular formula: C30H53N3O6.1/2(C4H4O4). Mole weight: 609.79. | |
| Alismoxide | The anti-inflammatory effects. Uses: Alismoxide has anti-inflammatory effects. Synonyms: (1S,3aR,4R,8aS)-1,2,3,3a,4,5,6,8a-Octahydro-1,4-dimethyl-7-(1-methylethyl)-1,4-azulenediol. Grades: >98%. CAS No. 87701-68-6. Molecular formula: C15H26O2. Mole weight: 238.37. | |
| Alisol A | Alisol A is a natural product, which is extracteed from the tubers of Alisma plantago-aquatica Linn. Synonyms: (23S,24R)-11b,23,24,25-Tetrahydroxydammar-13(17)-en-3-one; (8α,9β,14β,23S,24R)-11β,23,24,25-Tetrahydroxy-5α-dammar-13(17)-en-3-one. Grades: >98%. CAS No. 19885-10-0. Molecular formula: C30H50O5. | |
| Alisol A 24-acetate | Alisol A 24-acetate, a major active triterpenes isolated from a famous traditional chinese medicine called Rhizoma Alismatis, has been determined for the quality control of this crude drug. Synonyms: [(3R,4S,6R)-2,4-dihydroxy-6-[(5R,8S,9S,10S,11S,14R)-11-hydroxy-4,4,8,10,14-pentamethyl-3-oxo-1,2,5,6,7,9,11,12,15,16-decahydrocyclopenta[a]phenanthren-17-yl]-2-methylheptan-3-yl] acetate alisol A 24-acetate Alisol A (24-acetate) 18674-16-3 24-O-Acetylalis. Grades: >98%. CAS No. 18674-16-3. Molecular formula: C32H52O6. Mole weight: 532.75. | |
| Alisol B | Alisol B, derived from a traditional Chinese medicine called Alisma orientale Juzepczuk, has strong inhibitory effects on osteoclast formation in vitro which has the potential to treat bone disorders. Synonyms: (5R,8S,9S,10S,11S,14R)-17-[(2R,4S)-4-[(2R)-3,3-dimethyloxiran-2-yl]-4-hydroxybutan-2-yl]-11-hydroxy-4,4,8,10,14-pentamethyl-1,2,5,6,7,9,11,12,15,16-decahydrocyclopenta[a]phenanthren-3-one alisol B CHEBI:81104 18649-93-9. Grades: >98%. CAS No. 18649-93-9. Molecular formula: C30H48O4. Mole weight: 472.70. | |
| Alisol F | Alisol F is a natural product, which is extracted from the tubers of Alisma plantago-aquatica Linn. It suppresses iNOS induction. Synonyms: (8alpha, 9beta, 11beta, 14beta, 16beta, 23S, 24R)-16, 23-Epoxy-11, 24, 25-trihydroxydammar-13(17)-en-3-one. Grades: >98%. CAS No. 155521-45-2. Molecular formula: C30H48O5. Mole weight: 488.70. | |
| Alisol F 24-acetate | Alisol F 24-acetate represents a naturally sourced product that may possess a broad range of bioactivities. This product has gained particular interest as a reference standard in Qianghuo studies, a traditional Chinese medicinal herb, acknowledged to exhibit anti-rheumatic, anti-cold, and anti-headache properties. Alisol F 24-acetate reveals promising anti-tumor capacities and demonstrates potential as a therapeutic approach for inflammatory conditions. Synonyms: Dammar-13(17)-en-3-one, 24-(acetyloxy)-16,23-epoxy-11,25-dihydroxy-, (8α, 9β, 11β, 14β, 23S, 24R)-; (8α, 9β, 11β, 14β, 23S, 24R)-24-(Acetyloxy)-16, 23-epoxy-11, 25-dihydroxydammar-13(17)-en-3-one. Grades: >98%. CAS No. 443683-76-9. Molecular formula: C32H50O6. Mole weight: 530.75. | |
| Alisol G | Alisol G, a triterpenoid isolated from the rhizome of Alisma orientale, has hCE2 inhibitory effects. Synonyms: (5R,8S,9S,10S,11S,14R)-17-[(2R,4S,5S)-4,5-dihydroxy-6-methylhept-6-en-2-yl]-11-hydroxy-4,4,8,10,14-pentamethyl-1,2,5,6,7,9,11,12,15,16-decahydrocyclopenta[a]phenanthren-3-one Alisol G 155521-46-3 CHEMBL3121588. Grades: >98%. CAS No. 155521-46-3. Molecular formula: C30H48O4. Mole weight: 472.71. | |
| Alisporivir intermediate-1 | Alisporivir intermediate-1 is an intermediate in the synthesis of Alisporivir, which is used to treat inflammation and viral diseases. Synonyms: Alisporivir-1; D-Ala-Val-Val-Leu-Ala-D-Ala-Leu-Leu-Val-Aaa-Abu. Grades: ≥98%. CAS No. 882506-05-0. Molecular formula: C74H132N12O17. Mole weight: 1461.91. | |
| Alitame hydrate | Alitame Hydrate is a dipeptide amide derivative of aspartic acid, used as a potent sweetener. Synonyms: L-a-Aspartyl-N-(2,2,4,4-tetramethyl-3-thietanyl)-D-alaninamide hydrate; bis(N4-((R)-1-oxo-1-((2,2,4,4-tetramethylthietan-3-yl)amino)propan-2-yl)-D-asparagine) pentahydrate; D-Alaninamide, L-alpha-aspartyl-N-(2,2,4,4-tetramethyl-3-thietanyl)-, hydrate (2:5); (3S)-Amino-N-((1R)-1-((2,2,4,4-tetramethyl-3-thietanyl)carbamoy)ethyl)succinamic acid hydrate (2:5). Grades: ≥98%. CAS No. 99016-42-9. Molecular formula: 2(C14H25N3O4S).5H2O. Mole weight: 752.94. | |
| Alizapride hydrochloride | Alizapride is a dopamine antagonist with prokinetic and antiemetic effects used in the treatment of nausea and vomiting, including postoperative nausea and vomiting. Synonyms: 6-Methoxy-N-[[1-(2-propenyl)-2-pyrrolidinyl]methyl]-1H-benzotriazole-5-carboxamide Hydrochloride; Limican; Nausilen; Plitican; Vergentan; N-[(1-Allyl-2-pyrrolidinyl)methyl]-5-methoxy-1H-benzotriazole-6-carboxamide hydrochloride (1:1). Grades: >98%. CAS No. 59338-87-3. Molecular formula: C16H22ClN5O2. Mole weight: 351.83. | |
| Alizarin 1-methyl ether | Alizarin 1-methyl ether is an anthraquinones isolated from the roots of Morinda officinalis with antiosteoporotic activity. Study shows that 2-Hydroxy-1-methoxyanthraquinone promotes osteoblast proliferation and inhibits osteoclast TRAP activity. Synonyms: 2-Hydroxy-1-methoxyanthraquinone; 2-Hydroxy-1-methoxy-anthraquinone; 2-hydroxy-1-methoxyanthracene-9,10-dione. Grades: >98%. CAS No. 6170-6-5. Molecular formula: C15H10O4. Mole weight: 254.241. | |
| ALK5 Inhibitor II hydrochloride | ALK5 inhibitor II was identified as a cell permeable, selective inhibitor of the TGF-β type 1 activin like kinase receptor ALK5 (ALK5 autophosphorylation, IC50s = 4 nM, TGF-β cellular assay, IC50s = 18 nM, ALK5 binding in HepG2 cells, IC50s = 23 nM). This compound has been used to induce stem cell pluripotency by replacing the reprogramming transcription factor Sox2 via inhibition of the TGF-β signaling pathway and induction of Nanog transcription. This product is a hydrochloride form. Synonyms: E 616452; RepSox; SJN 2511. Grades: ≥98%. CAS No. 446859-33-2. Molecular formula: C17H13N5·HCl. Mole weight: 323.8. | |
| Alkanes, C6-18, chloro [Chlorinated paraffins] | Grades: 95%. CAS No. 68920-70-7. | |
| Alkannin | Alkannin is a potent and specific inhibitor of tumor-specific pyruvate kinase-M2 (PKM2). It inhibits proliferation, migration and invasion of human Huh7 and Hep3B2.1-7 hepatocellular carcinoma cells via regulation of miR92a. Synonyms: 1,4-Naphthalenedione, 5,8-dihydroxy-6-[(1S)-1-hydroxy-4-methyl-3-penten-1-yl]-; 1,4-Naphthalenedione, 5,8-dihydroxy-6-(1-hydroxy-4-methyl-3-pentenyl)-, (S)-; 1,4-Naphthalenedione, 5,8-dihydroxy-6-[(1S)-1-hydroxy-4-methyl-3-pentenyl]-; 1,4-Naphthoquinone, 5,8-dihydroxy-6-(1-hydroxy-4-methyl-3-pentenyl)-, (-)-; 5,8-Dihydroxy-6-[(1S)-1-hydroxy-4-methyl-3-penten-1-yl]-1,4-naphthalenedione; Alkanet extract; Alkanet extract, inspissated; Alkanna red; Anchusa acid; Anchusin; C.I. 75530; C.I. Natural Red 20. Grades: ≥95%. CAS No. 23444-65-7. Molecular formula: C16H16O5. Mole weight: 288.30. | |
| ALK inhibitor 1 | ALK inhibitor 1 is a novel and selective inhibitor for the ALK kinase. Synonyms: Benzenesulfonamide, 2-[[5-bromo-2-[[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]amino]-N-methyl-. Grades: >98%. CAS No. 761436-81-1. Molecular formula: C23H28BrN7O3S. Mole weight: 562.48. | |
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