BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| alpha-Endorphin | α-Endorphin is an endogenous neuropeptide that binds to opioid receptors. Uses: Neurotransmitter agents. Synonyms: Endorphin, Alpha; Lipotropin 61-76; A-Endorphin. Grade: ≥95%. CAS No. 59004-96-5. Molecular formula: C77H120N18O26S. Mole weight: 1745.95. |  |
| alpha-Endorphin acetate | alpha-Endorphin acetate is a related peptide of the pro-opiomelanocortin family with characteristic biological activities. α-Endorphin is an endogenous neuropeptide that binds to opioid receptors. Synonyms: Lipotropin 61-76 acetate; α-Endorphin acetate; 1-16-Human β-endorphin acetate; Human β-endorphin-(1-16) acetate; Porcine α-endorphin acetate; H-Tyr-Gly-Gly-Phe-Met-Thr-Ser-Glu-Lys-Ser-Gln-Thr-Pro-Leu-Val-Thr-OH.CH3CO2H; L-tyrosyl-glycyl-glycyl-L-phenylalanyl-L-methionyl-L-threonyl-L-seryl-L-alpha-glutamyl-L-lysyl-L-seryl-L-glutaminyl-L-threonyl-L-prolyl-L-leucyl-L-valyl-L-threonine acetate. Grade: ≥95%. Molecular formula: C79H124N18O28S. Mole weight: 1806.00. | |
| α-epidermal growth factor, human | Recombinant human epidermal growth factor has the same structure as the human epidermal growth factor. EGF binds to epidermal growth factor receptor (EGFR) and stimulates cell growth and proliferation. Recombinant human epidermal growth factor is approved for the treatment of diabetic foot ulcers. Uses: The treatment of diabetic foot ulcers. Synonyms: Human EGF; Nepidermin. CAS No. 62253-63-8. Molecular formula: C270H401N73O83S7. Mole weight: 6222. | |
| α-Factor Mating Pheromone, yeast | Alpha1-Mating Factor a tridecapeptide secreted by S. cerevisiae α cells via Ste2p receptor, facilitates in regulating the mating in yeast. Synonyms: Trp-His-Trp-Leu-Gln-Leu-Lys-Pro-Gly-Gln-Pro-Met-Tyr; Mating Factor α; alphaSC1-Pheromone; L-tryptophyl-L-histidyl-L-tryptophyl-L-leucyl-L-glutaminyl-L-leucyl-L-lysyl-L-prolyl-glycyl-L-glutaminyl-L-prolyl-L-methionyl-L-tyrosine. Grade: 95%. CAS No. 59401-28-4. Molecular formula: C82H114N20O17S. Mole weight: 1683.97. | |
| α-helical CRF 9-41 acetate | α-helical CRF 9-41 acetate, a salt of α-helical CRF 9-41 that is a competitive CRF2 receptor antagonist and a partial agonist of CRF1 receptor. Grade: >95.0%. Molecular formula: C168H276N46O54S2. Mole weight: 3868.44. | |
| α-Melanocyte-Stimulating Hormone (MSH), amide | α-Melanocyte-Stimulating Hormone (MSH), is an endogenous melanocortin receptor agonist that results in the activation of adenylyl cyclase, with anti-inflammatory effect. Synonyms: CZEN-002; CZEN002; CZEN 002; α-MSH; α-MSH, amide; α-Melanotropin; α-Melanocyte stimulating hormone. Grade: 98%. CAS No. 581-05-5. Molecular formula: C77H109N21O19S. Mole weight: 1637.88. | |
| α-MSH free acid | α-MSH is an MC3R and MC4R agonist with EC50s of 0.16 nM and 5.6 nM, respectively. It activates cAMP generation at MC3R and MC4R. Synonyms: (D-Leu2)-MIF-I; 13-Val-alpha-msh (1-13); alpha-Msh(1-13), valine(13)-; α-Melanocyte-Stimulating Hormone free acid. Grade: >95%. CAS No. 10466-28-1. Molecular formula: C77H108N20O20S. Mole weight: 1665.87. | |
| alpha-Zearalenol-[d5] | α-Zearalenol-[d5] is a labelled impurity of Zearalenol. Zearalenol, a resorcylic acid lactones derivative, could be produced by Fusarium fungi in grains and has been found to be an environmental contaminant. Synonyms: α-Zearalenol-d5; (E)-(7S,11R)-2,4,11-Trihydroxy-7-methyl-7,8,9,10,11,12,13,14-octahydro-10,10,11,12,12-D5-6-oxa-benzocyclotetradecen-5-one; (-)-α-Zearalenol-d5; Zearalenol-d5; trans-Zearalenol-d5; (3S,7R,11E)-3,4,5,6,7,8,9,10-Octahydro-7,14,16-trihydroxy-3-methyl-1H-2-benzoxacyclotetradecin-1-one-d5. Grade: 95% by HPLC; 98% atom D. CAS No. 36455-72-8. Molecular formula: C18H19D5O5. Mole weight: 325.41. | |
| Altenuene | (-)-Altenuene is a toxin isolated from the fungus Alternaria tenuis. It has antioxidant activity and inhibits cholinesterases. Synonyms: (2R,3R,4aR)-2,3,4,4a-Tetrahydro-2,3,7-trihydroxy-9-methoxy-4a-methyl-6H-dibenzo[b,d]pyran-6-one. Grade: >95%. CAS No. 29752-43-0. Molecular formula: C15H16O6. Mole weight: 292.29. | |
| Aluminum calcium borate oxide silicate (Al1.94Ca0.01(BO3)0.02O2.88(SiO4)0.01) | Aluminum calcium borate oxide silicate (Al1.94Ca0.01(BO3)0.02O2.88(SiO4)0.01). CAS No. 64082-85-5. | |
| Aluminum calcium isopropoxide, in isopropanol | Aluminum calcium isopropoxide, in isopropanol. CAS No. 23275-27-6. Molecular formula: Ca[Al(OCH(CH3)2)4]2. Mole weight: 566.3. | |
| Aluminum calcium silicate(2:1:2) | Aluminum calcium silicate(2:1:2). CAS No. 37342-39-5. Molecular formula: Al2CaO8Si2. Mole weight: 278.21. | |
| Aluminum dicalcium iron pentaoxide | Aluminum dicalcium iron pentaoxide. Synonyms: aluminium dicalcium iron pentaoxide; ALUMINUM CALCIUM IRON OXIDE; calcium iron aluminate Ca2FeAlO5. Grade: 95%. CAS No. 12068-35-8. Molecular formula: AlCa2FeO5. Mole weight: 242.979538. | |
| Alvespimycin | Alvespimycin (17-DMAG; KOS-1022; NSC 707545) is a potent, water-soluble Hsp90 inhibitor with IC50 of 62 nM. 17-DMAG displays ~2 times potency against human Hsp90 than 17-AAG, with IC50 of 62 nM versus 119 nM. In SKBR3 and SKOV3 cells which overexpress Hsp90 client protein Her2, 17-DMAG causes down-regulation of Her2 with EC50 of 8 nM and 46 nM, respectively, as well as induction of Hsp70 with EC50 of 4 nM and 14 nM, respectively, leading to significant cytotoxicity with GI50 of 29 nM and 32 nM, respectively, consistent with Hsp90 inhibition. In combination with vorinostat, 17-DMAG synergistically induces apoptosis of the cultured MCL cells as well as primary MCL cells, more potently than either agent alone, by markedly attenuating the levels of cyclin D1 and CDK4, as well as of c-Myc, c-RAF and Akt. 17-DMAG treatment at 5 mg/kg or 25 mg/kg three times per week significantly reduces tumor growth of TMK-1 xenografts, by reducing vessel area and numbers of proliferating tumor cells in sections. Consistent the inhibition of FAK signaling in vivo, 17-DMAG treatment at 25 mg/kg three times a week significantly suppresses tumor growth, and metastasis of ME180 and SiHa xenografts in mice. Administration of 17-DMAG at 10 mg/kg for 16 days significantly decreases the white blood cell count and prolongs the survival in a TCL1-SCID transplant mouse model. Uses: Hsp-90 inhibitor; potential anti-cancer drug. Synonyms: 17-DMAG; KOS 1022; K | |
| Amastatin hydrochloride | Amastatin, also known as 3-amino-2-hydroxy-5-methylhexanoyl-L-valyl-L-valyl-L-aspartic acid, is a naturally occurring, competitive and reversible aminopeptidase inhibitor. Amastatin has originally been isolated from the culture filtrate of Streptomyces sp. ME98-M3 and is a competitive inhibitor of human serum aminopeptidase A (Ki = 1.1 · 10?? M) and of pig kidney leucine aminopeptidase (Ki = 1.6 · 10?? M). Amastatin hydrochloride has been shown to slightly decrease the conversion of angiontensin II to angiotensin III, but significantly increases the potency of angiotensin III and des(Asp1)angiotensin I. Synonyms: BIMI-1803; J-000280; ZX-AFC000547; Amastatin HCl. Grade: ≥95%. CAS No. 100938-10-1. Molecular formula: C21H39ClN4O8. Mole weight: 511.01. | |
| Ambuic acid | Ambuic acid is a cyclohexanone originally isolated from Pestalotiopsis and Monochaetia species. Antibiotic medications are widely used in the treatment and prevention of such infections. They may either kill or inhibit the growth of bacteria. It is active against P. ultimum (MIC = 7.5 μg/ml) and inhibits the growth of a variety of other phytopathogenic fungi. Ambuic acid inhibits the biosynthesis of cyclic peptides involved in quorum sensing, including gelatinase biosynthesis-activating pheromone (GBAP). Synonyms: (+)-Ambuic acid; (2E,5R,6R,7R,8E,10E)-2-Methyl-5,9-carbonyl-5,6-epoxy-7-hydroxy-8-(hydroxymethyl)-2,8,10-hexadecatrienoic acid. Grade: ≥95%. CAS No. 340774-69-8. Molecular formula: C19H26O6. Mole weight: 350.41. | |
| AMCA-Glu-Glu-Lys-Pro-Ile-Ser-Phe-Phe-Arg-Leu-Gly-Lys(biotinyl)-NH2 | AMCA-Glu-Glu-Lys-Pro-Ile-Ser-Phe-Phe-Arg-Leu-Gly-Lys(biotinyl)-NH2. CAS No. 851231-19-1. Molecular formula: C90H131N21O22S. | |
| Amdinocillin | Mainly resistant to gram-negative bacteria. Uses: Active antibacterial against gram-negative bacteria. Synonyms: Mecillinam. Grade: ≥95%. CAS No. 32887-01-7. Molecular formula: C15H23N3O3S. Mole weight: 325.43. | |
| Amdinocillin pivoxil | Antibiotics, oral. Uses: Anti-bacterial agents. Synonyms: Pivmecillinam. CAS No. 32886-97-8. Molecular formula: C21H33N3O5S. Mole weight: 439.57. | |
| Amicetin A | It is produced by the strain of Streptomuces vinaceusdrappus. The antibacterial activity is lower than that of Amicetin. Synonyms: AMICETIN; Amicetin-A; (4S)-N-{(4S)-1-[(2R,5S,6R)-5-{[4,6-dideoxy-4-(dimethylamino)-alpha-D-glucopyranosyl]oxy}-6-methyloxan-2-yl]-2-oxo-1,2,3,4-tetrahydropyrimidin-4-yl}-4-[(2-methyl-D-seryl)amino]cyclohexa-1,5-diene-1-carboxamide. CAS No. 17650-86-1. Molecular formula: C29H42N6O9. Mole weight: 618.68. | |
| Amicoumacin A | It is produced by the strain of Bacillus pumilus BN-103. It has anti-gram-positive bacterial activity and can inhibit foot paw edema (inflammation) caused by carrageenan in rats, which is similar to Phenylbutazone, and has a stronger effect on preventing gastric ulcer in rats than Sulpiride. Synonyms: Antibiotic BN 103; (3S)-3alpha-[(S)-1-[[(2S,3S,4S)-1,6-Dioxo-2,3-dihydroxy-4,6-diaminohexyl]amino]-3-methylbutyl]-8-hydroxy-3,4-dihydro-1H-2-benzopyran-1-one. CAS No. 56592-30-4. Molecular formula: C20H29N3O7. Mole weight: 423.46. | |
| Amicoumacin B | It is produced by the strain of Bacillus pumilus BN-103. It is an antibiotic that resists gram-positive bacteria. Synonyms: Hexonic acid, 3-amino-2,3,6-trideoxy-6-[[1-(3,4-dihydro-8-hydroxy-1-oxo-1H-2-benzopyran-3-yl)-3-methylbutyl]amino]-6-oxo-. CAS No. 82768-33-0. Molecular formula: C20H28N2O8. Mole weight: 424.44. | |
| Amidepsine A | It is produced by the strain of Humicola sp. FO-2942. It inhibits DGAT activity, and the IC50 of rat liver microsomes DGAT is 10.1 X 10-6mol/L. It also inhibits triacylglycerol formation in intact Raji cells. Synonyms: Benzoic acid,2,4-dimethoxy-6-methyl-,4-[[4-[[(1-carboxyethyl)amino]carbonyl]-3-hydroxy-5-methylphenoxy]carbonyl]-3-hydroxy-5-methylphenylester (9ci); FO-2942A. Grade: ≥95%. CAS No. 169181-28-6. Molecular formula: C29H29NO11. Mole weight: 567.54. | |
| Amidepsine D | It is produced by the strain of Humicola sp. FO-2942. It inhibits DGAT activity, and the IC50 of rat liver microsomes DGAT is 17.5 X 10-6 mol/L. It also inhibits triacylglycerol formation in intact Raji cells. Synonyms: 2,4-di-O-methylgyrophoric acid; 4-[(2,4-Dimethoxy-6-methylbenzoyl)oxy]-2-hydroxy-6-methyl-Benzoic Acid 4-Carboxy-3-hydroxy-5-methylphenyl Ester. Grade: ≥95%. CAS No. 79786-34-8. Molecular formula: C26H24O10. Mole weight: 496.46. | |
| Amikacin | It has a wide antibacterial spectrum and is effective to most kanamycin resistant bacteria. Uses: Anti-bacterial agents. Synonyms: (S)-O-3-Amino-3-deoxy-α-D-glucopyranosyl-(1→6)-O-[6-amino-6-deoxy-α-D-glucopyranosyl-(1→4)]-N1-(4-amino-2-hydroxy-1-oxobutyl)-2-deoxy-D-streptamine; 1-N-[L-(-)-γ-Amino-α-hydroxybutyryl]kanamycin A; Amicacin; Amikacillin; Amikacin; Amikozit; Amukin; Antibiotic BB-K 8; Arikace; BAY 41-6551; BAY 416651; BB-K 8; Lukadin; Potentox. Grade: 98%. CAS No. 37517-28-5. Molecular formula: C22H43N5O13. Mole weight: 585.60. | |
| Amine-PEG3-Desthiobiotin | Amine-PEG3-Desthiobiotin is a biotin-PEG derivative for biotinylation. The desthiobiotin group serves as an affinity label towards the proteins avidin and streptavidin like biotin but is elutable from streptavidin. Grade: >95%. CAS No. 2237234-71-6. Molecular formula: C18H36N4O5. Mole weight: 388.5. | |
| Amine-PEG4-Desthiobiotin | Amine-PEG4-Desthiobiotin is a biotin-PEG derivative for biotinylation. The desthiobiotin group serves as an affinity label towards the proteins avidin and streptavidin like biotin but is elutable from streptavidin. Synonyms: Amine-PEG4-Desthiobiotin; 2306109-91-9; N-(14-amino-3,6,9,12-tetraoxatetradecan-1-yl)-6-[(4R,5S)-5-methyl-2-oxoimidazolidin-4-yl]hexanamide; AKOS040757538; HY-134720; CS-0148303; G76711. Grade: >95%. Molecular formula: C20H40N4O6. Mole weight: 432.29. | |
| Aminocaproic acid | Aminocaproic acid is a derivative and analogue of the amino acid lysine, which makes it an effective inhibitor for enzymes that bind that particular residue. Such enzymes include proteolytic enzymes like plasmin, the enzyme responsible for fibrinolysis. Uses: Antifibrinolytic agents. Synonyms: Aminocaproic acid; NSC 400230; NSC-400230; NSC400230. Grade: >98%. CAS No. 60-32-2. Molecular formula: C6H13NO2. Mole weight: 131.17. | |
| Aminomethylated resin | Aminomethylated resin. Synonyms: Aminomethyl Resin; AM Resin. | |
| Amlodipine aspartic acid impurity | Amlodipine Aspartic Acid Impurity is an impurity of Amlodipine. Amlodipine is a long-acting dihydropyridine L-type calcium channel blocker. Amlodipine is used to lower blood pressure and prevent chest pain. Synonyms: Amlodipine Aspartate; L-Aspartate Amlodipine; (2-((4-(2-Chlorophenyl)-3-(ethoxycarbonyl)-5-(methoxycarbonyl)-6-methyl-1,4-dihydropyridin-2-yl)methoxy)ethyl)aspartic acid; Amlodipine Impurity 24. Grade: ≥95%. CAS No. 400602-35-9. Molecular formula: C24H29ClN2O9. Mole weight: 524.95. | |
| AmmTX3 | AmmTX3 is a peptide that can be isolated from the venom of Androctonus mauretanicus and belongs scorpion toxin of the α-KTX15 subfamily. It is a specific potassium 4 (Kv4) channel blocker and could reduce the A-type potassium current in mouse cerebellar granule neurons through this channel. It has specific high-affinity blockade for Kv4.2 and Kv4.3 channels of mice because of expression of dipeptidyl peptidase-like proteins (DPP) DPP6 and DPP10. It also has a small blocking effect on hERG channels without alteration of the gating kinetics. Grade: >98%. Molecular formula: C158H262N50O48S6. Mole weight: 3822.47. | |
| Amodiaquin dihydrochloride dihydrate | Amodiaquine, a 4-aminoquinoquinoline compound, is a histamine N-methyltransferase inhibitor, used as an antimalarial and anti-inflammatory agent for more than 40 years. Uses: Antimalarial. Synonyms: AMODIAQUIN DIHYDROCHLORIDE; amodiaquin dihydrochloride dihydrate; AMODIAQUINE DIHYDROCHLORIDE; AMODIAQUINE HCL; AMODIAQUIN HYDROCHLORIDE; 4-[(7-CHLORO-4-QUINOLINYL)AMINO]-2-[(DIETHYLAMINO)METHYL]PHENOL DIHYDROCHLORIDE; 4-([7-chloro-4-quinolinyl]amino)-2-([diet. Grade: >98%. CAS No. 6398-98-7. Molecular formula: C20H28Cl3N3O3. Mole weight: 464.81. | |
| Amoxicillin | Amoxicillin is one of the commonly used anti-infective drugs. The antibacterial spectrum and antibacterial activity were similar to ampicillin, oral absorption was better than ampicillin, LD50 was 25g/kg (mouse, oral). It can prevent and treat infections caused by various Gram-positive and negative bacteria including Escherichia coli, Salmonella paratyphi, Streptococcus, Haemophilus parasuis, Actinobacillus pleuropneumoniae, etc. Uses: Anti-bacterial agents. Synonyms: Amoxycillin; Amoxicilline; p-Hydroxyampicillin; Amopenixin; Amolin; Moxal; D-Amoxicillin; Clamoxyl; Amoxil; Amoxicillinum; Amoxicilina; Delacillin. Grade: > 98%. CAS No. 26787-78-0. Molecular formula: C16H19N3O5S. Mole weight: 365.40. | |
| Amoxicillin sodium salt | Amoxicillin Sodium is a moderate-spectrum, bacteriolytic, β-lactam antibiotic. It is effective against a variety of other gram-negative and gram-positive bacteria. Uses: Anti-bacterial agents. Synonyms: Clavulanate. Grade: >98%. CAS No. 34642-77-8. Molecular formula: C16H18N3O5SNa. Mole weight: 387.39. | |
| Amphomycin | It is produced by the strain of Streptomyces canus. It is primarily resistant to gram-positive bacteria. Synonyms: Amfomycine; Amfomycinum; Anfomicina; Glumamycin; Amfomycin; A1437E. Grade: >95% by HPLC. CAS No. 1402-82-0. Molecular formula: C58H91N13O20. Mole weight: 1290.41. | |
| Amphotericin B | It is produced by the strain of Streptomyces nodosus. It is an important antifungal drug, especially for deep fungal infection. Liposomes were prepared to reduce toxic and side effects. Synonyms: Amfotericina B; Amphotericinum B; AMPH-B; Fungizone; Liposomal; Amphotericine B; Ambisome; Amphozone; Fungilin; NSC 527017; NSC527017; NSC-527017; (1R,3S,5R,6R,9R,11R,15S,16R,17R,18S,19E,21E,23E,25E,27E,29E,31E,33R,35S,36R,37S)-33-[(3-Amino-3,6-dideoxy-β-D-mannopyranosyl)oxy]-1,3,5,6,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylic acid; 14,39-Dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylic acid, 33-[(3-amino-3,6-dideoxy-β-D-mannopyranosyl)oxy]-1,3,5,6,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-, (1R,3S,5R,6R,9R,11R,15S,16R,17R,18S,19E,21E,23E,25E,27E,29E,31E,33R,35S,36R,37S)-; Abelcet; Abelecet; Ampho-Moronal; Amphocin; Apothecon; Fungizona; Halizon; Kalsome 10; LNS-AmB; NS 718. Grade: >98%. CAS No. 1397-89-3. Molecular formula: C47H73NO17. Mole weight: 924.08. | |
| Ampicillin | Ampicillin is a broad-spectrum antibiotic used to prevent and treat a variety of bacterial infections. It is used to treat infectious diseases caused by sensitive chicken bacteria, such as Escherichia coli, Salmonella, Pasteurella, Staphylococcus and Streptococcus infections. Synonyms: Piperacillin EP Impurity A; (2S,5R,6R)-6-[(2R)-2-Amino-2-phenylacetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid; Pentrexyl; Principen; D-(-)-α-Aminobenzylpenicillin; Sultamicillin EP Impurity C; Aminobenzylpenicillin; Ampicillin acid; Amcill; Polycillin; Principen; Omnipen; Ampicilline; Penbritin; 6-[D-(-)-α-Aminophenylacetamido]penicillanic acid; D-(-)-6-(α-Aminophenylacetamido)penicillanic acid; D-(-)-α-Aminopenicillin; D-Ampicillin; Piperacillin sodium Impurity A [EP]; Piperacillin Monohydrate Impurity A [EP]. Grade: >98%. CAS No. 69-53-4. Molecular formula: C16H19N3O4S. Mole weight: 349.40. | |
| AMY-101 | C3 Complement Inhibitor AMY-101 is a compstatin-based inhibitor of human complement component C3. AMY-101 (Cp40) exhibits a favorable anti-inflammatory activity in models with COVID-19 severe pneumonia with systemic hyper inflammation. Uses: Amy-101 is a promising peptide api, also known as the c3 complement inhibitor amy-101, with unique properties. the complement system is an important component of the immune response and plays a key role in the recognition and elimination of pathogens and the clearance of damaged cells and immune complexes. however, dysregulation of the complement system can lead to various diseases, including infl. Synonyms: Compstatin 40; Cp40. Grade: ≥98%. CAS No. 1427001-89-5. Molecular formula: C83H117N23O18S2. Mole weight: 1789.11. | |
| Amylin (1-13) (human) | Amylin (1-13) (human) does not form fibrils, and this region may be involved in amylin binding to the membranes. Synonyms: Diabetes-Associated Peptide (1-13) (human); H-Lys-Cys-Asn-Thr-Ala-Thr-Cys-Ala-Thr-Gln-Arg-Leu-Ala-OH (Disulfide bridge: Cys2-Cys7); L-lysyl-L-cysteinyl-L-asparagyl-L-threonyl-L-alanyl-L-threonyl-L-cysteinyl-L-alanyl-L-threonyl-L-glutaminyl-L-arginyl-L-leucyl-L-alanine (2->7)-disulfide; Islet Amyloid Polypeptide (1-13) (human); DAP (1-13) (human); Insulinoma Amyloid Peptide (1-13) (human); IAPP 1-13. Grade: ≥95% by HPLC. CAS No. 198328-30-2. Molecular formula: C54H95N19O19S2. Mole weight: 1378.58. | |
| Amylin (20-29) (human) | Amylin (20-29) (human) forms fibrils ultrastructurally identical to amyloid fibrils seen in pancreatic islets. The region SNNFGAILSS appears to be the most important amyloidogenic sequence of hIAPP (human islet amyloid polypeptide). Synonyms: H-Ser-Asn-Asn-Phe-Gly-Ala-Ile-Leu-Ser-Ser-OH; L-seryl-L-asparagyl-L-asparagyl-L-phenylalanyl-glycyl-L-alanyl-L-isoleucyl-L-leucyl-L-seryl-L-serine; Amylin Fragment 20-29 human; Diabetes Associated Peptide Fragment 20-29 human; hIAPP 20-29. Grade: 95%. CAS No. 118068-30-7. Molecular formula: C43H68N12O16. Mole weight: 1009.07. | |
| Amylin (8-37) (human) | Amylin (8-37) (human), a fragment of human Amylin, readily forms fibrils in vitro and exhibits direct vasodilation effect in isolated rat mesenteric resistance arteries. Human amylin is a small hormone secreted by pancreatic beta cells, which forms aggregates in insulin-deficient metabolism and is a pathological feature of type II diabetes. Synonyms: H-Ala-Thr-Gln-Arg-Leu-Ala-Asn-Phe-Leu-Val-His-Ser-Ser-Asn-Asn-Phe-Gly-Ala-Ile-Leu-Ser-Ser-Thr-Asn-Val-Gly-Ser-Asn-Thr-Tyr-NH2; L-alanyl-L-threonyl-L-glutaminyl-L-arginyl-L-leucyl-L-alanyl-L-asparagyl-L-phenylalanyl-L-leucyl-L-valyl-L-histidyl-L-seryl-L-seryl-L-asparagyl-L-asparagyl-L-phenylalanyl-glycyl-L-alanyl-L-isoleucyl-L-leucyl-L-seryl-L-seryl-L-threonyl-L-asparagyl-L-valyl-glycyl-L-seryl-L-asparagyl-L-threonyl-L-tyrosinamide; Human IAPP (8-37). Grade: ≥95%. CAS No. 135702-23-7. Molecular formula: C138H216N42O45. Mole weight: 3183.48. | |
| Amylin (8-37), rat | Amylin (8-37), rat is a truncated natural Amylin analogue that selectively inhibits insulin-related glucose uptake and glycogen deposition in muscle tissue. Synonyms: Amylin (8-37) (mouse, rat); H-Ala-Thr-Gln-Arg-Leu-Ala-Asn-Phe-Leu-Val-Arg-Ser-Ser-Asn-Asn-Leu-Gly-Pro-Val-Leu-Pro-Pro-Thr-Asn-Val-Gly-Ser-Asn-Thr-Tyr-NH2; L-alanyl-L-threonyl-L-glutaminyl-L-arginyl-L-leucyl-L-alanyl-L-asparagyl-L-phenylalanyl-L-leucyl-L-valyl-L-arginyl-L-seryl-L-seryl-L-asparagyl-L-asparagyl-L-leucyl-glycyl-L-prolyl-L-valyl-L-leucyl-L-prolyl-L-prolyl-L-threonyl-L-asparagyl-L-valyl-glycyl-L-seryl-L-asparagyl-L-threonyl-L-tyrosinamide. Grade: ≥95%. CAS No. 138398-61-5. Molecular formula: C140H227N43O43. Mole weight: 3200.61. | |
| Amylin, amide, rat acetate | Amylin, amide, rat acetate is a potent and high-affinity ligand for the AMY1 and AMY3 receptors and variably of AMY2 receptors. Synonyms: H-Lys-Cys-Asn-Thr-Ala-Thr-Cys-Ala-Thr-Gln-Arg-Leu-Ala-Asn-Phe-Leu-Val-Arg-Ser-Ser-Asn-Asn-Leu-Gly-Pro-Val-Leu-Pro-Pro-Thr-Asn-Val-Gly-Ser-Asn-Thr-Tyr-NH2.CH3CO2H (Disulfide bridge: Cys2-Cys7); L-lysyl-L-cysteinyl-L-asparagyl-L-threonyl-L-alanyl-L-threonyl-L-cysteinyl-L-alanyl-L-threonyl-L-glutaminyl-L-arginyl-L-leucyl-L-alanyl-L-asparagyl-L-phenylalanyl-L-leucyl-L-valyl-L-arginyl-L-seryl-L-seryl-L-asparagyl-L-asparagyl-L-leucyl-glycyl-L-prolyl-L-valyl-L-leucyl-L-prolyl-L-prolyl-L-threonyl-L-asparagyl-L-valyl-glycyl-L-seryl-L-asparagyl-L-threonyl-L-tyrosinamide (2->7)-disulfide acetic acid; Amylin (rat) acetate; Rat amylin acetate; Rat amylin amide acetate; Rat islet amyloid polypeptide acetate. Grade: ≥95%. Molecular formula: C169H276N52O55S2. Mole weight: 3980.45. | |
| Amylin (human) | Amylin, islet Amyloid Polypeptide (IAPP), is a 37-residue peptide hormone secreted by pancreatic β-cells. It inhibits insulin-stimulated glucose uptake, delays gastric emptying and promotes satiety. It has glucose lowering effects in vivo. It is also used to study the mechanisms of amyloid deposition and its role in molecular misfolding processes expecially in conditions such as diabetes type II. Synonyms: L-Tyrosinamide, L-lysyl-L-cysteinyl-L-asparaginyl-L-threonyl-L-alanyl-L-threonyl-L-cysteinyl-L-alanyl-L-threonyl-L-glutaminyl-L-arginyl-L-leucyl-L-alanyl-L-asparaginyl-L-phenylalanyl-L-leucyl-L-valyl-L-histidyl-L-seryl-L-seryl-L-asparaginyl-L-asparaginyl-L-phenylalanylglycyl-L-alanyl-L-isoleucyl-L-leucyl-L-seryl-L-seryl-L-threonyl-L-asparaginyl-L-valylglycyl-L-seryl-L-asparaginyl-L-threonyl-, cyclic (2→7)-disulfide; AC 001; Amlintide; Amylin (human clone WO2013/156594-SEQID-1); Diabetes-associated peptide (human); Human amylin; Human IAPP; Human islet amyloid peptide; Human islet amyloid polypeptide; Human islet amyloid polypeptide-NH2; Islet amyloid polypeptide (human); H-Lys-Cys-Asn-Thr-Ala-Thr-Cys-Ala-Thr-Gln-Arg-Leu-Ala-Asn-Phe-Leu-Val-His-Ser-Ser-Asn-Asn-Phe-Gly-Ala-Ile-Leu-Ser-Ser-Thr-Asn-Val-Gly-Ser-Asn-Thr-Tyr-NH2 (Disulfide bridge: Cys2-Cys7). Grade: 95%. CAS No. 122384-88-7. Molecular formula: C165H261N51O55S2. Mole weight: 3903.33. | |
| Amylin (rat) | Amylin (rat), islet Amyloid Polypeptide (IAPP), is a glucoregulatory peptide from rat pancreatic cells. It inhibits glucagon secretion, delays gastric emptying and acts as a satiety agent. It is used to study the regulation of satiety and obesity. It binds to heteromeric complexes of human calcitonin receptor 2 (CTR2) with receptor activity-modifying protein (RAMP) 1 or 3. It also binds to mouse α-thyroid-stimulating hormone thyrotroph (α-TSH) cells and rat nucleus accumbens membrane preparations. It inhibits insulin-induced, but not basal, glycogen synthesis in hepatocytes isolated from fasted rats in vitro. It does not form fibrils and is not cytotoxic unlike human amylin. It is active in vivo. Synonyms: Amylin, amide, rat; Amylin (mouse, rat); IAPP (mouse, rat); Islet amyloid polypeptide (mouse, rat); H-Lys-Cys(1)-Asn-Thr-Ala-Thr-Cys(1)-Ala-Thr-Gln-Arg-Leu-Ala-Asn-Phe-Leu-Val-Arg-Ser-Ser-Asn-Asn-Leu-Gly-Pro-Val-Leu-Pro-Pro-Thr-Asn-Val-Gly-Ser-Asn-Thr-Tyr-NH2; L-lysyl-L-cysteinyl-L-asparagyl-L-threonyl-L-alanyl-L-threonyl-L-cysteinyl-L-alanyl-L-threonyl-L-glutaminyl-L-arginyl-L-leucyl-L-alanyl-L-a. Grade: ≥98%. CAS No. 124447-81-0. Molecular formula: C167H272N52O53S2. Mole weight: 3920.43. | |
| Amyloid β-peptide (1-40) rat | Amyloid β-peptide (1-40) (rat) is the rat form of the amyloid β-peptide found in plaques, which is the major constituent observed in the brain of Alzheimer's disease. It is the prone-to-aggregation product of amyloid precursor protein proteolytic cleavage. It is shown to have both neurotrophic and neurotoxic effects. Synonyms: β-Amyloid (1-40), rat; H-Asp-Ala-Glu-Phe-Gly-His-Asp-Ser-Gly-Phe-Glu-Val-Arg-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-OH; L-alpha-aspartyl-L-alanyl-L-alpha-glutamyl-L-phenylalanyl-glycyl-L-histidyl-L-alpha-aspartyl-L-seryl-glycyl-L-phenylalanyl-L-alpha-glutamyl-L-valyl-L-arginyl-L-histidyl-L-glutaminyl-L-lysyl-L-leucyl-L-valyl-L-phenylalanyl-L-phenylalanyl-L-alanyl-L-alpha-glutamyl-L-alpha-aspartyl-L-valyl-glycyl-L-seryl-L-asparagyl-L-lysyl-glycyl-L-alanyl-L-isoleucyl-L-isoleucyl-glycyl-L-leucyl-L-methionyl-L-valyl-glycyl-glycyl-L-valyl-L-valine; Rat amyloid-beta peptide 1-40; Rat amyloid-β peptide 1-40; Amyloid b-Protein (1-40) (Mouse, rat). Grade: ≥95%. CAS No. 144409-98-3. Molecular formula: C190H291N51O57S. Mole weight: 4233.76. | |
| Amyloid β-peptide (1-42) human | Amyloid β-Peptide (12-28) (human), an Amyloid β-peptide fragment, binds with high affinity to α7-nicotinic ACh receptors. It impairs memory retention following central administration in mice. Uses: Implicated in alzheimer's disease. Synonyms: β-Amyloid (1-42), human; beta-Amyloid (1-42) human; Amyloid Beta Protein Fragment 1-42; H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala-OH; L-alpha-aspartyl-L-alanyl-L-alpha-glutamyl-L-phenylalanyl-L-arginyl-L-histidyl-L-alpha-aspartyl-L-seryl-glycyl-L-tyrosyl-L-alpha-glutamyl-L-valyl-L-histidyl-L-histidyl-L-glutaminyl-L-lysyl-L-leucyl-L-valyl-L-phenylalanyl-L-phenylalanyl-L-alanyl-L-alpha-glutamyl-L-alpha-aspartyl-L-valyl-glycyl-L-seryl-L-asparagyl-L-lysyl-glycyl-L-alanyl-L-isoleucyl-L-isoleucyl-glycyl-L-leucyl-L-methionyl-L-valyl-glycyl-glycyl-L-valyl-L-valyl-L-isoleucyl-L-alanine; Abeta 42 protein; amyloid beta-protein (1-42). Grade: ≥95%. CAS No. 107761-42-2. Molecular formula: C203H311N55O60S. Mole weight: 4514.04. | |
| Amyloid β-peptide (1-42) (rat) | Amyloid β-peptide (1-42) (rat) is the rat form of the predominant amyloid β-peptide found in plaques associated with Alzheimer's disease. It could lead to a large shift in the bax/bcl-2 ratio in favour of pro-apoptotic bax. It is neurotoxic. Synonyms: Amyloid β-Protein (1-42) (mouse, rat); beta-Amyloid Peptide (1-42) (rat/mouse). CAS No. 166090-74-0. Molecular formula: C199H307N53O59S. Mole weight: 4418.02. | |
| Amyloid β-Peptide (1-43) (human) | Amyloid β-Peptide (1-43) (human) is the minor component of neuritic plaques, which is the primary constituent of senile plaques and cerebrovascular deposits in Alzheimer's disease and Down's syndrome. It is neurotrophic and neurotoxic. Synonyms: β-Amyloid (1-43); Amyloid β-Protein Fragment 1-43; H-DL-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-D-Glu-D-Asp-D-Val-Gly-D-Ser-D-Asn-D-Lys-Gly-D-Ala-D-xiIle-D-xiIle-Gly-D-Leu-D-Met-D-Val-Gly-Gly-D-Val-D-Val-D-xiIle-D-Ala-D-xiThr-OH. CAS No. 134500-80-4. Molecular formula: C207H318N56O62S. Mole weight: 4615.19. | |
| Amyloid beta-peptide (25-35) | Amyloid beta-peptide(25-35), the fragment Aβ(25-35) of the Alzheimer's amyloid β-peptide, is functionally required for the neurotrophic and neurotoxic effects associated with Alzheimer's disease. Synonyms: H-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-OH; glycyl-L-seryl-L-asparagyl-L-lysyl-glycyl-L-alanyl-L-isoleucyl-L-isoleucyl-glycyl-L-leucyl-L-methionine; Amyloid β-Protein (25-35); Amyloid-Protein (25-35). CAS No. 131602-53-4. Molecular formula: C45H81N13O14S. Mole weight: 1060.27. | |
| Amyloid beta-peptide (25-35) 2TFA | Amyloid beta-peptide (25-35) 2TFA, the fragment Aβ(25-35) of the Alzheimer's amyloid β-peptide, is functionally required for the neurotrophic and neurotoxic effects associated with Alzheimer's disease. Synonyms: GSNKGAIIGLM 2TFA; H-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-OH.2TFA; glycyl-L-seryl-L-asparagyl-L-lysyl-glycyl-L-alanyl-L-isoleucyl-L-isoleucyl-glycyl-L-leucyl-L-methionine trifluoroacetic acid; Amyloid β-peptide (25-35) trifluoroacetate; Aβ25-35 trifluoroacetate; Eledoisin, 1-glycine-2-L-serine-3-L-asparagine-5-glycine-7-L-isoleucine-11-L-methionine-, trifluoroacetate; Human β-amyloid peptide (25-35) trifluoroacetate; β-Amyloid fragment(25-35) trifluoroacetate; β-Amyloid peptide(25-35) trifluoroacetate. Grade: ≥95%. Molecular formula: C49H83F6N13O18S. Mole weight: 1288.32. | |
| Amyloid β-peptide (42-1) human | Amyloid β-peptide (42-1) (human), is the predominant form of amyloid β-peptide found in the brains of patients with Alzheimer's disease. Uses: Implicated in alzheimer's disease. Synonyms: H-Ala-Ile-Val-Val-Gly-Gly-Val-Met-Leu-Gly-Ile-Ile-Ala-Gly-Lys-Asn-Ser-Gly-Val-Asp-Glu-Ala-Phe-Phe-Val-Leu-Lys-Gln-His-His-Val-Glu-Tyr-Gly-Ser-Asp-His-Arg-Phe-Glu-Ala-Asp-OH; L-alanyl-L-isoleucyl-L-valyl-L-valyl-glycyl-glycyl-L-valyl-L-methionyl-L-leucyl-glycyl-L-isoleucyl-L-isoleucyl-L-alanyl-glycyl-L-lysyl-L-asparagyl-L-seryl-glycyl-L-valyl-L-alpha-aspartyl-L-alpha-glutamyl-L-alanyl-L-phenylalanyl-L-phenylalanyl-L-valyl-L-leucyl-L-lysyl-L-glutaminyl-L-histidyl-L-histidyl-L-valyl-L-alpha-glutamyl-L-tyrosyl-glycyl-L-seryl-L-alpha-aspartyl-L-histidyl-L-arginyl-L-phenylalanyl-L-alpha-glutamyl-L-alanyl-L-aspartic acid; Amyloid beta (42-1) human; Amyloid b-Protein (42-1). Grade: ≥95%. CAS No. 317366-82-8. Molecular formula: C203H311N55O60S. Mole weight: 4514.04. | |
| Amyloid β-Protein 10-20 | Amyloid β protein (10-20) is a fragment of Amyloid β peptide that may be used in the study of neurological diseases. Synonyms: H-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-OH; L-tyrosyl-L-alpha-glutamyl-L-valyl-L-histidyl-L-histidyl-L-glutaminyl-L-lysyl-L-leucyl-L-valyl-L-phenylalanyl-L-phenylalanine; Amyloid b-Protein (10-20); Amyloid B-protein fragment 10-20. Grade: ≥95%. CAS No. 152286-31-2. Molecular formula: C71H99N17O16. Mole weight: 1446.65. | |
| Amyloid β-Protein 10-20 acetate | Amyloid β-Protein (10-20) acetate is a fragment of Amyloid β peptide that may be used in the study of neurological diseases. Synonyms: H-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-OH.CH3CO2H; L-tyrosyl-L-alpha-glutamyl-L-valyl-L-histidyl-L-histidyl-L-glutaminyl-L-lysyl-L-leucyl-L-valyl-L-phenylalanyl-L-phenylalanine acetic acid. Grade: ≥95%. Molecular formula: C73H103N17O18. Mole weight: 1506.65. | |
| Amyloid β-Protein (1-38) | Like Aβ (25-35), Amyloid β-Protein (1-38) disrupts calcium homeostasis, making human cortical neurons vulnerable to environmental insults. Synonyms: H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-OH; L-alpha-aspartyl-L-alanyl-L-alpha-glutamyl-L-phenylalanyl-L-arginyl-L-histidyl-L-alpha-aspartyl-L-seryl-glycyl-L-tyrosyl-L-alpha-glutamyl-L-valyl-L-histidyl-L-histidyl-L-glutaminyl-L-lysyl-L-leucyl-L-valyl-L-phenylalanyl-L-phenylalanyl-L-alanyl-L-alpha-glutamyl-L-alpha-aspartyl-L-valyl-glycyl-L-seryl-L-asparagyl-L-lysyl-glycyl-L-alanyl-L-isoleucyl-L-isoleucyl-glycyl-L-leucyl-L-methionyl-L-valyl-glycyl-glycine. Grade: 95%. CAS No. 131438-74-9. Molecular formula: C184H277N51O56S1. Mole weight: 4131.54. | |
| Amyloid β-Protein (1-40)-Lys(biotinyl) amide | Amyloid β-Protein (1-40)-Lys(biotinyl) amide is used for immobilization of Aβ40. The biotinylation of the peptide and the location of the biotin portion (N- or C-terminus) seem to influence aggregation behavior. Similar effects are observed at the N- or C-terminal of Aβ42 biotinylation. Synonyms: Abeta (1-40) Lys (Biotin) amide; H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Lys(biotinyl)-NH2. Grade: ≥95%. Molecular formula: C210H322N58O60S2. Mole weight: 4683.35. | |
| Amyloid β-Protein (1-42)-Lys(biotinyl) amide | Amyloid β-Protein (1-42)-Lys(biotinyl) amide is used for immobilization of Aβ42. N-terminal biotinylated and C-terminal biotinylated Aβ42 binding may behave differently on surfaces. Synonyms: Beta-Amyloid (1-42)-Lys(biotin) amide; H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala-Lys(biotinyl)-NH2. Grade: ≥95%. Molecular formula: C219H338N60O62S2. Mole weight: 4867.53. | |
| Amyloid β-Protein (1-46) | Amyloid β-Protein (1-46) is a precursor of the secreted amyloid β-protein (1-40) and (1-42). The identification of amyloid β-protein (1-46) led to the identification of a zeta-cleavage site between the known γ- and ε-cleavage sites within the transmembrane domain of amyloid-β precursor protein (APP). Synonyms: β-Amyloid (1-46); H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala-Thr-Val-Ile-Val-OH; L-alpha-aspartyl-L-alanyl-L-alpha-glutamyl-L-phenylalanyl-L-arginyl-L-histidyl-L-alpha-aspartyl-L-seryl-glycyl-L-tyrosyl-L-alpha-glutamyl-L-valyl-L-histidyl-L-histidyl-L-glutaminyl-L-lysyl-L-leucyl-L-valyl-L-phenylalanyl-L-phenylalanyl-L-alanyl-L-alpha-glutamyl-L-alpha-aspartyl-L-valyl-glycyl-L-seryl-L-asparagyl-L-lysyl-glycyl-L-alanyl-L-isoleucyl-L-isoleucyl-glycyl-L-leucyl-L-methionyl-L-valyl-glycyl-glycyl-L-valyl-L-valyl-L-isoleucyl-L-alanyl-L-threonyl-L-valyl-L-isoleucyl-L-valine. Grade: ≥95%. CAS No. 285554-31-6. Molecular formula: C223H347N59O65S. Mole weight: 4926.61. | |
| Amyloid β-Protein (33-42) | Amyloid β-Protein (33-42) is a partial sequence of β-amyloid protein, which is used to raise antibodies against Aβ 1-42. Synonyms: APP770 (704-713); H-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala-OH; glycyl-L-leucyl-L-methionyl-L-valyl-glycyl-glycyl-L-valyl-L-valyl-L-isoleucyl-L-alanine; L-Alanine, glycyl-L-leucyl-L-methionyl-L-valylglycylglycyl-L-valyl-L-valyl-L-isoleucyl-; β-Amyloid (33-42). Grade: ≥95% by HPLC. CAS No. 178949-81-0. Molecular formula: C41H74N10O11S. Mole weight: 915.15. | |
| Amyloid β-Protein (40-1) | Amyloid β-Protein (40-1) is an inactive control of Amyloid β-Protein (1-40). Synonyms: β-Amyloid (40-1); H-Val-Val-Gly-Gly-Val-Met-Leu-Gly-Ile-Ile-Ala-Gly-Lys-Asn-Ser-Gly-Val-Asp-Glu-Ala-Phe-Phe-Val-Leu-Lys-Gln-His-His-Val-Glu-Tyr-Gly-Ser-Asp-His-Arg-Phe-Glu-Ala-Asp-OH; L-valyl-L-valyl-glycyl-glycyl-L-valyl-L-methionyl-L-leucyl-glycyl-L-isoleucyl-L-isoleucyl-L-alanyl-glycyl-L-lysyl-L-asparagyl-L-seryl-glycyl-L-valyl-L-alpha-aspartyl-L-alpha-glutamyl-L-alanyl-L-phenylalanyl-L-phenylalanyl-L-valyl-L-leucyl-L-lysyl-L-glutaminyl-L-histidyl-L-histidyl-L-valyl-L-alpha-glutamyl-L-tyrosyl-glycyl-L-seryl-L-alpha-aspartyl-L-histidyl-L-arginyl-L-phenylalanyl-L-alpha-glutamyl-L-alanyl-L-aspartic acid. Grade: ≥95%. CAS No. 144409-99-4. Molecular formula: C194H295N53O58S. Mole weight: 4329.86. | |
| Amyloid β-Protein Fragment 35-25 | Amyloid β-Protein Fragment 35-25, the reverse sequence of Aβ 25-35, serves as an inactive control. Synonyms: H-Met-Leu-Gly-Ile-Ile-Ala-Gly-Lys-Asn-Ser-Gly-OH; Amyloid β-Protein (35-25); β-Amyloid (35-25); L-methionyl-L-leucyl-glycyl-L-isoleucyl-L-isoleucyl-L-alanyl-glycyl-L-lysyl-L-asparagyl-L-seryl-glycine. Grade: ≥95%. CAS No. 147740-73-6. Molecular formula: C45H81N13O14S. Mole weight: 1060.27. | |
| Andrastin A | It is produced by the strain of Penicillum sp. FO-3929. It can inhibit PFTase. IC50 is 24.9 μmol/L. Synonyms: NSC 697452; NSC697452; NSC-697452. Grade: ≥95%. CAS No. 174232-42-9. Molecular formula: C28H38O7. Mole weight: 486.60. | |
| Angiogenin 108-122 | Angiogenin (108-122) is an angiogenin peptide. Synonyms: H-Glu-Asn-Gly-Leu-Pro-Val-His-Leu-Asp-Gln-Ser-Ile-Phe-Arg-Arg-OH; L-alpha-glutamyl-L-asparagyl-glycyl-L-leucyl-L-prolyl-L-valyl-L-histidyl-L-leucyl-L-alpha-aspartyl-L-glutaminyl-L-seryl-L-isoleucyl-L-phenylalanyl-L-arginyl-L-arginine; Angiogenin fragment 108-122. Grade: ≥95%. CAS No. 112173-49-6. Molecular formula: C78H125N25O23. Mole weight: 1780.98. | |
| Angiotensin (1-12) (human) | Angiotensin (1-12) (human) is cleaved by chymase in human cardiac tissue to produce angiotensin II. Synonyms: Angiotensinogen (1-12) (human); H-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu-Val-Ile-OH; L-alpha-aspartyl-L-arginyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-prolyl-L-phenylalanyl-L-histidyl-L-leucyl-L-valyl-L-isoleucine; Proangiotensin-12 (human); Angiotensin I, 5-L-isoleucine-10a-L-valine-10b-L-isoleucine-; α-Protensin(human). Grade: 95%. CAS No. 136865-09-3. Molecular formula: C73H109N19O16. Mole weight: 1508.79. | |
| Angiotensin 1/2 (1-9) TFA | Angiotensin 1/2 (1-9) TFA contains the amino acids 1-9 that are converted from Angiotensin I/II peptide. It is an anti-cardiac hypertrophy drug with the functions of human metabolite, rat metabolite, antihypertensive agent and cardiac protective agent. Synonyms: Angiotensin I (1-9) TFA; Angiotensin I (1-9) trifluoroacetate; H-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-OH.TFA; L-alpha-aspartyl-L-arginyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-prolyl-L-phenylalanyl-L-histidine trifluoroacetic acid; 5-L-Isoleucine-1-9-angiotensin I trifluoroacetate; 1-9-(5-Ile)-Angiotensin trifluoroacetate; 1-9-Angiotensin I (human) trifluoroacetate. Grade: ≥95%. Molecular formula: C58H79F3N16O15. Mole weight: 1297.36. | |
| Angiotensin A | Angiotensin A is a potent endogenous vasoconstrictor octapeptide. It is a derivative of angiotensin II (Ang II) that differs from Ang II in having alanine instead of aspartic acid as the first amino acid. It shows similar affinity for AT1 and AT2 receptors as angiotensin II with Ki values of 1.6 and 2.3 nM in vitro. It causes pressor and renal vasoconstrictor effects in rodents by the AT1 receptor. It is inhibited by Candesartan but not by AT2 receptor ligands in vivo. It also increases inositol phosphate accumulation with a similar potency to Ang II with EC50 value of 6.7 nM. Synonyms: Ala-Angiotensin III; H-Ala-Arg-Val-Tyr-Ile-His-Pro-Phe-OH; Ang A; Angiotensin II, 1-L-alanine-5-L-isoleucine-; L-alanyl-L-arginyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-prolyl-L-phenylalanine. Grade: ≥95%. CAS No. 51833-76-2. Molecular formula: C49H71N13O10. Mole weight: 1002.18. | |
| Angiotensin Acetate | Angiotensin acetate is an angiotensin II analog that is an agonist at angiotensin receptors. It is an oligopeptide and is a hormone and a powerful dipsogen. It is derived from the precursor molecule angiotensinogen, a serum globulin produced in the liver. It is a peptide hormone that causes vasoconstriction and a subsequent increase in blood pressure. It is part of the renin-angiotensin system, which is a major target for drugs that lower blood pressure. It plays an important role in the renin-angiotensin system. It also stimulates the release of aldosterone, another hormone, from the adrenal cortex. Uses: Angiotensin acetate causes vasoconstriction and a subsequent increase in blood pressure. it plays an important role in the renin-angiotensin system. Synonyms: ASP-ARG-VAL-TYR-VAL-HIS-PRO-PHE; H-ASP-ARG-VAL-TYR-VAL-HIS-PRO-PHE-OH; Angiotensin II 5-valine; Valine angiotensin II; 5-L-Valine angiotensin II. Grade: 98%. CAS No. 58-49-1. Molecular formula: C49H69N13O12. Mole weight: 1032.15. | |
| Angiotensin I (1-9) | Angiotensin I (1-9) is a 9-amino acid peptide formed when Angiotensin converting enzyme 2 (ACE2) hydrolyzes the carboxy-terminal leucine of Angiotensin I. It is an anti-cardiac hypertrophy drug with the functions of human metabolite, rat metabolite, antihypertensive agent and cardiac protective agent. Synonyms: H-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-OH; L-alpha-aspartyl-L-arginyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-prolyl-L-phenylalanyl-L-histidine; L-Asp-L-Arg-L-Val-L-Tyr-L-Ile-L-His-L-Pro-L-Phe-L-His. Grade: ≥95% by HPLC. CAS No. 34273-12-6. Molecular formula: C56H78N16O13. Mole weight: 1183.32. | |
| Angiotensin I human acetate salt hydrate | Angiotensin 1 (Human), an endogenous peptide substrate for angiotensin converting enzyme (ACE), is precursor to the vasoconstrictor peptide angiotensin II. Synonyms: H-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu-OH.CH3CO2H.H2O. Grade: 98%. CAS No. 70937-97-2. Molecular formula: C64H95N17O17. Mole weight: 1374.54. | |
| Angiotensin I (human, mouse, rat) | Angiotensin 1 (Human), an endogenous peptide substrate for angiotensin converting enzyme (ACE), is precursor to the vasoconstrictor peptide angiotensin II. Synonyms: Angiotensin 1 Human; H-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu-OH; L-alpha-aspartyl-L-arginyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-prolyl-L-phenylalanyl-L-histidyl-L-leucine; Pepsitensin; Proangiotensin; 5-Ile-angiotensin I; 5-L-Isoleucine-angiotensin I. Grade: ≥95%. CAS No. 484-42-4. Molecular formula: C62H89N17O14. Mole weight: 1296.48. | |
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