BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Angiotensin II (3-8), human | Angiotensin II (3-8), human is a less effective agonist of the angiotensin AT1 receptor. Synonyms: 3-8-Angiotensin II; Angiotensin II, 1-de-L-aspartic acid-2-de-L-arginine-; Angiotensin IV; 3-8-Angiotensin; 3-8-Angiotensin II hexapeptide; Angiotensin II C-terminal hexapeptide; Angiotensin II3-8; Des-1,2-angiotensin II. Grade: ≥95%. CAS No. 12676-15-2. Molecular formula: C40H54N8O8. Mole weight: 774.91. |  |
| Angiotensin I/II 1-5 | Angiotensin I/II 1-5 is a peptide containing amino acids 1-5 that is converted from Angiotensin I/II. Synonyms: Angiotensin (1-5); H-DRVYI-OH; L-alpha-aspartyl-L-arginyl-L-valyl-L-tyrosyl-L-isoleucine; L-α-Aspartyl-N5-(diaminomethylene)-L-ornithyl-L-valyl-L-tyrosyl-L-isoleucine. Grade: ≥95%. CAS No. 58442-64-1. Molecular formula: C30H48N8O9. Mole weight: 664.75. | |
| Angiotensin I/II 1-6 | Angiotensin I/II 1-6 is a peptide containing amino acids 1-6 that is converted from Angiotensin I/II. Synonyms: H-Asp-Arg-Val-Tyr-Ile-His-OH; L-alpha-aspartyl-L-arginyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidine; Angiotensin (1-6); 1-6-Angiotensin II, 5-L-isoleucine-; Angiotensin 1/2 1-6; L-α-Aspartyl-N5-(diaminomethylene)-L-ornithyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidine. Grade: ≥95%. CAS No. 47896-63-9. Molecular formula: C36H55N11O10. Mole weight: 801.89. | |
| Angiotensin I/II (1-7) | Angiotensin-(1-7) is an endogenous ligand for the G protein-coupled receptor, inducing vasorelaxation through release of NO and prostaglandins. Uses: Endogenous peptide fragment. Synonyms: Angiotensin II (1-7) heptapeptide; TXA127; TXA 127; TXA127; Angiotensin i (1-7); therapeutic angiotensin(17)H-Asp-Arg-Val-Tyr-Ile-His-Pro-OH. Grade: ≥90%. CAS No. 51833-78-4. Molecular formula: C41H62N12O11. Mole weight: 899. | |
| Angiotensin III (human, mouse) | Angiotensin III (Ang III) is generated from Ang II by APA (and subsequently degraded by aminopeptidase N), and that central Ang III seems to play a key-role in vasopressin release and BP control. Angiotensin III, human, mouse is a heptapeptide agonist, which acts as an endogenous angiotensin type 2 receptor (AT2R) agonist. The IC50 values for AT2R is 0.648 nM and the IC50 values for AT1R is 21.1 nM. The biologically active COOH-terminal heptapeptide angiotensin III is bound more tightly than angiotensin II. Synonyms: H-Arg-Val-Tyr-Ile-His-Pro-Phe-OH; L-arginyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-prolyl-L-phenylalanine; Ang III; Angiotensin III; 5-Ile-angiotensin III; 1-Desaspartyl-5-isoleucine angiotensin II; Des-asp(1)-(Ile(5))-angiotensin II; N5-(Diaminomethylene)-L-ornithyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-prolyl-L-phenylalanine; 2-8-angiotensin II, 5-L-isoleucine-. Grade: ≥95%. CAS No. 13602-53-4. Molecular formula: C46H66N12O9. Mole weight: 931.09. | |
| Angiotensinogen (1-14), human | Angiotensinogen (1-14), human is a fragment of the renin substrate Angiotensinogen, a precursor for all angiotensin peptides. Synonyms: H-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu-Val-Ile-His-Asn-OH; L-alpha-aspartyl-L-arginyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-prolyl-L-phenylalanyl-L-histidyl-L-leucyl-L-valyl-L-isoleucyl-L-histidyl-L-asparagine; Renin Substrate Tetradecapeptide human. Grade: 95%. CAS No. 104180-23-6. Molecular formula: C83H122N24O19. Mole weight: 1760.00. | |
| Angiotensinogen (1-14), Porcine | Angiotensin is a peptide hormone that causes vasoconstriction and an increase in blood pressure. Uses: Serine proteinase inhibitors. Synonyms: H-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-LEU-LEU-VAL-TYR-SER-OH; ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-LEU-LEU-VAL-TYR-SER; ANGIOTENSINOGEN FRAGMENT 1-14 PORCINE; ANGIOTENSINOGEN (1-14), PORCINE; ANGIOTENSINOGEN (1-14) (HORSE); ANGIOTENSINOGEN; PREANGIOTENSINOGEN (. Grade: 95%. CAS No. 64315-16-8. Molecular formula: C85H123N21O20. Mole weight: 1759. | |
| Angiotensinogen(tetradecapeptide renin substrate), 5-L-isoleucine- (9CI) | Angiotensin is a peptide hormone that causes vasoconstriction and an increase in blood pressure. Synonyms: Hypertensinogen; Porcine renin substrate tetradecapeptide. CAS No. 20845-02-7. Molecular formula: C85H123N21O20. Mole weight: 1759. | |
| Angolamycin | It is produced by the strain of Streptomyces eurythermus. It has anti-gram-positive bacteria activity and has effect on Mycoplasma pneumoniae Mac. Synonyms: Sincomycin A; Angolamycin, BRN 6045489; LS-19552; 2-[(14E)-9-[5-(4,5-dihydroxy-4,6-dimethyl-tetrahydropyran-2-yl)oxy-4-(dimethylamino)-6-methyl-tetrahydropyran-2-yl]oxy-3-ethyl-7-hydroxy-2-[(5-hydroxy-3,4-dimethoxy-6-methyl-tetrahydropyran-2-yl)oxymethyl]-8,12,16-trimethyl-5,13-dioxo-4,17-dioxabicyclo[14.1.0]heptadec-14-en-10-yl]acetaldehyde. CAS No. 1402-83-1. Molecular formula: C46H77NO17. Mole weight: 916.10. | |
| Anguidin | It is produced by the strain of Fusarium anguioides. It showed weak antifungal activity, and 0.03 μg/mL completely inhibited the mitosis of chicken embryo fibroblasts cultured in vitro. The inhibition rate of 0.51mg/kg/d in vivo for 7 consecutive days was 79%, 70% and 50%, respectively, for Walker cancer, sarcoma 37 and sarcoma 180 in rats. Synonyms: Diacetoxyscirpenol; Anguidine; 4,15-Diacetoxyscirpen-3-ol; CHEBI:4478; 4,15-Di-O-acetylscirpenol; Scirpenetriol 4,15-diacetate; NSC177378; ANG 66; 4,15-Diacetoxyscirp-9-en-3-ol; 4,15-Diacetoxyscirpenol; 12,13-Epoxytrichothec-9-ene-3alpha,4beta,15-triol 4,15-diacetate; 3-alpha-Hydroxy-4-beta,15-diacetoxy-12,13-epoxytrichothec-9-ene. Grade: ≥97%. CAS No. 2270-40-8. Molecular formula: C19H26O7. Mole weight: 366.40. | |
| Anguinomycin A | It is produced by the strain of Streptomyces sp. R2827 and R2827-2. It has anti-rat Lewis lung cancer and P388 leukemia activity. It has been reported that it can cause normal cell growth to stop and deformable cell death. Synonyms: 5-Demethylleptomycin A, KR 2827A. Grade: >95% by HPLC. CAS No. 111278-01-4. Molecular formula: C31H44O6. Mole weight: 512.68. | |
| Angustmycin A | It is produced by the strain of Streptomyces hygroscopicus var. angustmyceticus. It has anti-gram-positive bacteria and mycobacterium activity. Synonyms: Adenosine, 4',5'-didehydro-1'-C-(hydroxymethyl)-; 4',5'-Didehydro-1'-C-(hydroxymethyl)adenosine; 9H-Purin-6-amine, 9-(6-deoxy-β-D-erythro-hex-5-en-2-ulofuranosyl)-; Adenine, 9-(6-deoxy-β-D-erythro-hex-5-enulofuranosyl)-; Angustomycin A; Decoyinin; 5,6-Psicofuranosenyladenine; Antibiotic A 14; Decoyinine; Guvermectin; Wugufengin; Wugufengsu; 9-(6-Deoxy-beta-D-erythro-hex-5-en-2-ulofuranosyl)-9H-purin-6-amine; 9-(6-Deoxy-beta-D-erythro-hex-5-enulofuranosyl)adenine; (2R,3R,4S)-2-(6-Amino-9H-purin-9-yl)-2-(hydroxymethyl)-5-methylenetetrahydrofuran-3,4-diol. Grade: ≥95% by HPLC. CAS No. 2004-4-8. Molecular formula: C11H13N5O4. Mole weight: 279.25. | |
| Angustmycin C | It is produced by the strain of Streptomyces hygroscopicus var. angustmyceticus. It has anti-gram-positive bacteria and mycobacterium activity, and has an inhibitory effect on Walker cancer 256 in rats and adenocarcinoma Ca755 in mice. Synonyms: Angustmycin C; NSC 53104; Psicofuranosyladenine; 1'-(Hydroxymethyl)adenosine; (2R,3R,4S,5R)-2-(6-aminopurin-9-yl)-2,5-bis(hydroxymethyl)oxolane-3,4-diol. Grade: ≥98%. CAS No. 1874-54-0. Molecular formula: C11H15N5O5. Mole weight: 297.27. | |
| Anhydrochlortetracycline hydrochloride | Anhydrochlortetracycline is a degradation product of chlorotetracycline formed by acid-catalysed isomerisation of the dimethylamino group at C4. It strongly inhibits the growth of Streptomyces aureofaciem, and shows a rather specific activity against actinomycetes. Synonyms: (4S,4aS,12aS)-7-Chloro-4-(dimethylamino)-1,4,4a,5,12,12a-hexahydro-3,10,11,12a-tetrahydroxy-6-methyl-1,12-dioxo-2-naphthacenecarboxamide Hydrochloride; Anhydroaureomycin Hydrochloride; Anhydro Chlortetracyline Monohydrochloride; [4S-(4α,4aα,12aα)]-7-Chloro-4-(dimethylamino)-1,4,4a,5,12,12a-hexahydro-3,10,11,12a-tetrahydroxy-6-methyl-1,12-dioxo-2-naphthacenecarboxamide Hydrochloride. Grade: >98% by HPLC. CAS No. 65490-24-6. Molecular formula: C22H22Cl2N2O7. Mole weight: 497.33. | |
| Anhydrotetracycline hydrochloride | Anhydrotetracycline acts as an inducer of tetracycline resistance genes by binding to and inactivating the tetracycline repressor TetR to allow expression of downstream genes of the tetr promoter. However, anhydrotetracycline binds to the TetR repressor with higher affinity without toxic effects. Anhydrotetracycline poorly binds the 30S ribosomal subunit, the concentration of anhydrotetracycline that inhibits eukaryotic cell growth is more than 1,000-fold above the dose that alters transcription through TetR. Synonyms: (4S,4aS,12aS)-4-(Dimethylamino)-3,10,11,12a-tetrahydroxy-6-methyl-1,12-dioxo-1,4,4a,5,12,12a-hexahydro-2-tetracenecarboxamide hydrochloride (1:1). Grade: ≥98%. CAS No. 13803-65-1. Molecular formula: C22H22N2O7.HCl. Mole weight: 462.88. | |
| Anidulafungin | Anidulafungin, is a semisynthetic echinocandin that inhibits glucan synthase, an enzyme important in the formation of (1→3)-β-D-glucan, a major fungal cell wall component, and thus is used as an antifungal drug. Synonyms: Eraxis; Ecalta; LY303366; 1-[(4R,5R)-4,5-dihydroxy-N2-[[4''-(pentyloxy)[1,1':4',1''-terphenyl]-4-yl]carbonyl]-L-ornithine]-echinocandin B. Grade: >98%. CAS No. 166663-25-8. Molecular formula: C58H73N7O17. Mole weight: 1140.24. | |
| Anisindione | Anisindione, an anticoagulant, could avoid the generation of active procoagulation factors and sorts of proteins in the liver. Uses: Anisindione is an anticoagulant and could avoid the generation of active procoagulation factors and sorts of proteins in the liver. Synonyms: Anisindione; Miradon; Anisin indandione; Unidone; 2-(4-Methoxyphenyl)-1H-indene-1,3(2H)-dione. Grade: 98%. CAS No. 117-37-3. Molecular formula: C16H12O3. Mole weight: 252.26. | |
| Anisomycin | It is produced by the strain of Streptomyces griseolus. It inhibits protein synthesis. it has anti-fungal, anti-fine bacteria, anti-tumor and antigenic insect action. Synonyms: Flagecidin; NSC-76712; AI3-50846; NSC76712; AI350846; NSC 76712; AI3 50846. Grade: ≥98%. CAS No. 22862-76-6. Molecular formula: C14H19NO4. Mole weight: 265.30. | |
| Anominine | Anominine is an indole diterpenoid isolated from new Aspergillus species, which has insecticidal activity. Synonyms: Nominine; (+)-Nominine. Grade: >95% by HPLC. CAS No. 120991-21-1. Molecular formula: C28H39NO. Mole weight: 405.6. | |
| Ansamitocin P 3' | Ansamitocin P 3' is an isomer of Ansamitocin P-3, a potent anti-tumor maytansinoid antibiotic found in Actinosynnema pretiosum, a maytansine analog which displays potent cytotoxicity against the human solid tumor cell lines A-549 and HT-29. Uses: Adcs cytotoxin. Synonyms: Ansamitocin P3'; AP-3'; Ansamitocin P-3'; Maytansinol butyrate, Maytansinoid AP-3'. Antibiotic C 15003P3'; iso-Ansamitocin P-3. Grade: >98%. CAS No. 66547-09-9. Molecular formula: C32H43ClN2O9. Mole weight: 635.14. | |
| Ansamitocin P-3 | It is produced by the strain of Nocardia sp. C-15003(N-1). It has the function of anti-tumor, anti-plant pathogenic fungi, skin fungi and protozoa, and has no antibacterial activity. Uses: Inhibitor of tublin spiralization,maytansine analog. Synonyms: 3-O-De[2-(acetylmethylamino)-1-oxopropyl]-3-O-(1-oxobutyl)-maytansine; 4,24-Dioxa-9,22-diazatetracyclo[19.3.1.110,14.03,5]hexacosane; maytansine deriv.; Ansamitocin P 3; Antibiotic C 15003P3; Maytansinol Butyrate. Grade: ≥90% by HPLC. CAS No. 66584-72-3. Molecular formula: C32H43N2O9Cl. Mole weight: 635.14. | |
| Ansatrienin A | It is produced by the strain of Streptomyces collinus Tu 1892, Str. rishiriensis and Str. diastatochromogenes var. diastatochromogenes. Ansaltriene has anti-mold and yeast activity, and has killing effect on HeLa S3, PLC liver cancer and other tumor cells. Synonyms: Mycotrienin I; CHEBI:29516; (+)-mycotrienin I; D-Alanine,N-(cyclohexylcarbonyl)-,11-ester with ansatrienol A; D-Alanine, N-(cyclohexylcarbonyl)?-, (5R,?6E,?8E,?10E,?13S,?14R,?15R,?16Z)?-15-hydroxy-5-methoxy-14,?16-dimethyl-3,?22,?24-trioxo-2-azabicyclo[18.3.1]?tetracosa-6,?8,?10,?16,?20,?23-hexaen-13-yl ester; 2-Azabicyclo[18.3.1]tetracosane, D-alanine deriv.; Ansatrienine A. Grade: >99% by HPLC. CAS No. 82189-03-5. Molecular formula: C36H48N2O8. Mole weight: 636.77. | |
| Ansatrienin B | It is produced by the strain of Streptomyces collinus Tu 1892, Str. rishiriensis and Str. diastatochromogenes var. diastatochromogenes. Ansaltriene has anti-mold and yeast activity, and has killing effect on HeLa S3, PLC liver cancer and other tumor cells. Synonyms: Mycotrienin II; Antibiotic T 23II; [(4Z,6R,7R,8S,10Z,12Z,14Z,16R)-6,22,24-trihydroxy-16-methoxy-5,7-dimethyl-18-oxo-19-azabicyclo[18.3.1]tetracosa-1(23),4,10,12,14,20(24),21-heptaen-8-yl] (2R)-2-(cyclohexanecarbonylamino)propanoate; D-Alanine, N-(cyclohexylcarbonyl)?-, (5R,?6E,?8E,?10E,?13S,?14R,?15R,?16Z)?-15,?22,?24-trihydroxy-5-methoxy-14,?16-dimethyl-3-oxo-2-azabicyclo[18.3.1]?tetracosa-1(24)?,?6,?8,?10,?16,?20,?22-heptaen-13-yl ester; D-Alanine, N-(cyclohexylcarbonyl)-, 11-ester with 20,23-didehydro-20,23-dideoxo-20,23-dihydroxyansatrienol A; 2-Azabicyclo[18.3.1]tetracosane, D-alanine deriv.; (+)-Mycotrienin II. Grade: >95% by HPLC (< 5% Ansatrienin A). CAS No. 82189-04-6. Molecular formula: C36H50N2O8. Mole weight: 638.79. | |
| Antagonist G | Antagonist G is a substance P analog, which is a broad spectrum neuropeptide growth factor antagonist and antiproliferative agent. It was developed for the treatment of small cell lung cancer. It could inhibit neuropeptide-dependent and -independent proliferation of small cell lung cancer in vitro. It also inhibits growth of SCLC xenografts in mice in vivo. It blocks Swiss 3T3 cell growth induced by vasopressin, gastrin-releasing peptide and bradykinin. It activates JNK and stimulates apoptosis. It is an anticancer agent and is resistant to degradation by peptidases. Synonyms: [Arg6,D-Trp7,9,N-MePhe8]-Substance P(6-11). Grade: 98%. CAS No. 115150-59-9. Molecular formula: C49H66N12O6S. Mole weight: 951.20. | |
| Antennapedia Peptide | Antennapedia Peptide, a cell-penetrating 16 amino acid peptide originally derived from the 60 amino acid long homeodomain of the Drosophila transcription factor Antennapedia, is a member of the family of Cell-penetrating peptides. Synonyms: L-Arginyl-L-glutaminyl-L-isoleucyl-L-lysyl-L-isoleucyl-L-tryptophyl-L-phenylalanyl-L-glutaminyl-L-asparaginyl-L-arginyl-L-arginyl-L-methionyl-L-lysyl-L-tryptophyl-L-lysyl-L-lysine; N5-(diaminomethylidene)-L-ornithyl-L-glutaminyl-L-isoleucyl-L-lysyl-L-isoleucyl-L-tryptophyl-L-phenylalanyl-L-glutaminyl-L-asparaginyl-N5-(diaminomethylidene)-L-ornithyl-N5-(diaminomethylidene)-L-ornithyl-L-methionyl-L-lysyl-L-tryptophyl-L-lysyl-L-lysine; Penetratin; Penetratin-1; Arg-Gln-Ile-Lys-Ile-Trp-Phe-Gln-Asn-Arg-Arg-Met-Lys-Trp-Lys-Lys. Grade: ≥98%. CAS No. 188842-14-0. Molecular formula: C104H168N34O20S. Mole weight: 2246.73. | |
| Anthramycin | It is produced by the strain of Streptomyces refuineus var. thermotolerans. It has a weak activity against gram-negative bacteria, and has the effect of inhibiting metamorphoses, vaginal trichomonas and rat tube nematode. It has inhibitory effect on sarcoma 180, L-1210, CA-755, Ascitic ascites type and solid type cancer. Synonyms: Antramycin; ANTHRAMYCIN; Antibiotic PBA; (E)-5,10,11,11a-Tetrahydro-9,11-dihydroxy-8-methyl-5-oxo-1H-pyrrolo(2,1-c)(1,4)-benzodiazepine-2-acrylamide; 3-(9,11-dihydroxy-8-methyl-5-oxo-5,10,11,11a-tetrahydro-1H-benzo[e]pyrrolo[1,2-a][1,4]diazepine-2-yl)-acrylamide. CAS No. 4803-27-4. Molecular formula: C16H17N3O4. Mole weight: 315.32. | |
| Anthrose - ethylene diamine-N6-hydroxylhexanoic acid - biotin linker | Anthrose - ethylene diamine-N6-hydroxylhexanoic acid - biotin linker. | |
| Antibiotic JI 20A | Antibiotic JI 20A is an aminoglycoside antibiotic originally isolated from Micromonospora purpurea. Synonyms: 2-Deoxy-4-O-[3-deoxy-4-C-methyl-3-(methylamino)-β-L-arabinopyranosyl]-6-O-(2,6-diamino-2,6-dideoxy-α-D-gluco-hexopyranosyl)-L-streptamine; O-3-Deoxy-4-C-methyl-3-(methylamino)-β-L-arabinopyranosyl-(1→6)-O-[2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl-(1→4)]-2-deoxy-D-streptamine; Antibiotic JI-20A; JI 20A; (2R,3S,4R,5R,6R)-5-Amino-2-(aminomethyl)-6-(((1R,2S,3S,4R,6S)-4,6-diamino-3-(((2R,3R,4R,5R)-3,5-dihydroxy-5-methyl-4-(methylamino)tetrahydro-2H-pyran-2-yl)oxy)-2-hydroxycyclohexyl)oxy)tetrahydro-2H-pyran-3,4-diol. CAS No. 51846-97-0. Molecular formula: C19H39N5O9. Mole weight: 481.54. | |
| Antibiotic PF 1052 | Antibiotic PF 1052 is a fungal metabolite originally isolated from Phoma sp. It is active against S. aureus, S. parvulus, and C. perfringens (MICs = 3.13, 0.78, and 0.39 μg/ml, respectively). Antibiotic PF 1052 inhibits neutrophil migration in a wound assay and reduces pseudopodia formation. Synonyms: (E)-5-(sec-Butyl)-3-((2-(2,3-dimethyloxiran-2-yl)-6,8-dimethyl-1,2,4a,5,6,7,8,8a-octahydronaphthalen-1-yl)(hydroxy)methylene)-1-methylpyrrolidine-2,4-dione; PF 1052; 3-[[2-(2,3-Dimethyl-2-oxiranyl)-1,2,4a,5,6,7,8,8a-octahydro-6,8-dimethyl-1-naphthalenyl]hydroxymethylene]-1-methyl-5-(1-methylpropyl)-2,4-pyrrolidinedione. Grade: ≥95%. CAS No. 147317-15-5. Molecular formula: C26H39NO4. Mole weight: 429.59. | |
| Anticapsin | Anticapsin is an antibiotic produced by Streptomyces griseoplanus. It can also be produced by acid hydrolysis of Bacilysin. 3 μg/mL Anticapsin can inhibit the formation of hyaluronic acid capsule by Streptococcus pyogenes. Except for Salmonella gallisepticum (MIC 6.25 μg/mL), low concentration has no obvious antibacterial activity against other microorganisms. Synonyms: 7-Oxabicyclo[4.1.0]heptane-2-propanoic acid, (1R-(1.alpha.,2.alpha.(S*),6.alpha.))-. CAS No. 28978-07-6. Molecular formula: C9H13NO4. Mole weight: 199.20. | |
| Antide | Antide is a GnRH and LH-RH antagonist that displays potent anti-ovulatory and weak histamine release activity. Uses: Hormone antagonists. Synonyms: Iturelix; Nal-Lys-GnRH. CAS No. 112568-12-4. Molecular formula: C82H108ClN17O14. Mole weight: 1591.321. | |
| Antipain | Antipain, a protease inhibitor isolated from Actinomycetes, inhibits N-methyl-N'-nitro-N-nitrosoguanidine (MNNG)-induced transformation and increases chromosomal aberration. It restricts DNA synthesis and function of mice uterus. Uses: Protease inhibitors. Synonyms: [(S)-1-Carboxy-2-phenylethyl]carbamoyl-L-arginyl-L-valyl-argininal; L-valinamide, N2-[[((1S)-1-carboxy-2-phenylethyl)amino]carbonyl]-L-arginyl-N-[4-[(aminoiminomethyl)amino]-1-formylbutyl]-; Phe-CO-Arg-Val-L-Arg-H; N2-{[(1S)-1-Carboxy-2-phenylethyl]carbamoyl}-N5-(diaminomethylene)-L-ornithyl-N-{5-[(diaminomethylene)amino]-1-oxo-2-pentanyl}-L-valinamide. Grade: 95%. CAS No. 37691-11-5. Molecular formula: C27H44N10O6. Mole weight: 604.70. | |
| Antisauvagine-30 | Antisauvagine-30 is a selective, competitive and potent corticotropin-releasing factor CRF2 receptor antagonist with Kd values of 153.6 and 1.4 nM for binding to rat CRF1 and mouse CRF2β receptors respectively. It prevents stress-enhanced fear conditioning and MEK 1/2-dependent activation of ERK1/2 in mice in vivo. It inhibits sauvagine-stimulated cAMP accumulation in HEK-mCRF2β cells. Synonyms: (D-Phe11,His12)-Sauvagine (11-40); H-D-Phe-His-Leu-Leu-Arg-Lys-Met-Ile-Glu-Ile-Glu-Lys-Gln-Glu-Lys-Glu-Lys-Gln-Gln-Ala-Ala-Asn-Asn-Arg-Leu-Leu-Leu-Asp-Thr-Ile-OH; D-phenylalanyl-L-histidyl-L-leucyl-L-leucyl-L-arginyl-L-lysyl-L-methionyl-L-isoleucyl-L-alpha-glutamyl-L-isoleucyl-L-alpha-glutamyl-L-lysyl-L-glutaminyl-L-alpha-glutamyl-L-lysyl-L-alpha-glutamyl-L-lysyl-L-glutaminyl-L-glutaminyl-L-alanyl-L-alanyl-L-asparagyl-L-asparagyl-L-arginyl-L-leucyl-L-leucyl-L-leucyl-L-alpha-aspartyl-L-threonyl-L-isoleucine; 11-D-Phenylalanine-12-L-histidine-11-40-sauvagine (11-40). Grade: ≥95%. CAS No. 220673-95-0. Molecular formula: C161H274N48O46S. Mole weight: 3650.29. | |
| AP 811 | AP 811 has been found to be an NPR3 antagonist and could restrain Na+/K+ pump activity in rabbit ventricular cardiomyocytes. Synonyms: N2-[[4-[(2-Naphthalenylcarbonyl)amino]phenyl]acetyl]-L-arginyl-L-isoleucyl-L-α-aspartyl-N-[(2S)-2-methylbutyl]-L-argininamide; (S)-N2-[[4-[(2-Naphthalenylcarbonyl)amino]phenyl]acetyl]-L-arginyl-L-isoleucyl-L-α-aspartyl-N-(2-methylbutyl)-L-argininamide; AP811; AP-811. Grade: ≥95% by HPLC. CAS No. 124833-45-0. Molecular formula: C46H66N12O8. Mole weight: 915.09. | |
| APC 366 | APC 366, an inhibitor of tryptase, has been found to reduce airway inflammation and block postchallenge airway hyperresponsiveness in vivo. Synonyms: N-(1-Hydroxy-2-naphthoyl)-L-arginyl-L-prolinamide. Grade: >98%. CAS No. 158921-85-8. Molecular formula: C22H28N6O4. Mole weight: 440.5. | |
| Apelin-12 (human, bovine, mouse, rat) | Apelin-12 (human, bovine, mouse, rat), an endogenous ligand of the human orphan receptor APJ, lowers arterial blood pressure without altering heart rate in anesthetized rats. Its vasoactive effect may be related to the activation of endothelial nitric oxide synthase. Synonyms: Preproapelin (66-77) (human, bovine, mouse, rat); H-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe-OH; L-arginyl-L-prolyl-L-arginyl-L-leucyl-L-seryl-L-histidyl-L-lysyl-glycyl-L-prolyl-L-methionyl-L-prolyl-L-phenylalanine; (Des-Gln1)-Apelin-13 (human, bovine, mouse, rat); Apelin Precursor (66-77) (human, bovine, mouse, rat); N5-(Diaminomethylene)-L-ornithyl-L-prolyl-N5-(diaminomethylene)-L-ornithyl-L-leucyl-L-seryl-L-histidyl-L-lysylglycyl-L-prolyl-L-methionyl-L-prolyl-L-phenylalanine. Grade: ≥95% by HPLC. CAS No. 229961-08-4. Molecular formula: C64H103N21O14S. Mole weight: 1422.72. | |
| Apelin-13 | Apelin-13, an endogenous neuropeptide, is the ligand for the G-protein-coupled receptor APJ, an alternative coreceptor with CD4 for HIV-1 infection. Apelin-13 is generated from apelin-36, which is a putative receptor protein related to the angiotensin receptor (AT1). Apelin-13 exerted an acidification-rate-promoting activity in the CHO cells expressing the APJ receptor with EC50 value of 0.37 nM. Apelin-13 is a 13 amino acid polypeptide encoded by the apelin gene which yields a pre-proprotein that is processed to generate bioactive peptides. Apelin-13 is also involved in the learning and memory process. Synonyms: Apelin-13 (human, bovine, mouse, rat); H-Gln-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe-OH; L-glutaminyl-L-arginyl-L-prolyl-L-arginyl-L-leucyl-L-seryl-L-histidyl-L-lysyl-glycyl-L-prolyl-L-methionyl-L-prolyl-L-phenylalanine. Grade: ≥95%. CAS No. 217082-58-1. Molecular formula: C69H111N23O16S. Mole weight: 1550.85. | |
| Apelin-17 (Human, Bovine) | Apelin-17 (human, bovine) is an endogenous ligand of the G protein-coupled APJ receptor with EC50 value of 2.5 nM that is secreted by adipocytes. It potently inhibits forskolin-stimulated cAMP production in vitro. Synonyms: [Phe17]-Apelin 17. Grade: 98.86%. CAS No. 217082-57-0. Molecular formula: C96H156N34O20S. Mole weight: 2138.56. | |
| Apelin-36 (human) | Apelin-36 (human) is an endogenous ligand of the G protein-coupled APJ receptor with EC50 value of 20 nM that is secreted by adipocytes. It is the full-length mature peptide produced from the translated 77 amino acid prepropeptide. It acts primarily in the central nervous and peripheral system. It is important in regulating fluid homeostasis, cardiovascular function, insulin and hypertension sensitivity. It potently blocks HIV-1 and HIV-2 strains entry into cells expressing APJ and CD4 and limits HIV infection. It endogenously binds with high affinity to human APJ receptors expressed in HEK 293 cells. Synonyms: H-Leu-Val-Gln-Pro-Arg-Gly-Ser-Arg-Asn-Gly-Pro-Gly-Pro-Trp-Gln-Gly-Gly-Arg-Arg-Lys-Phe-Arg-Arg-Gln-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe-OH; L-leucyl-L-valyl-L-glutaminyl-L-prolyl-L-arginyl-glycyl-L-seryl-L-arginyl-L-asparagyl-glycyl-L-prolyl-glycyl-L-prolyl-L-tryptophyl-L-glutaminyl-glycyl-glycyl-L-arginyl-L-arginyl-L-lysyl-L-phenylalanyl-L-arginyl-L-arginyl-L-glutaminyl-L-arginyl-L-prolyl-L-arginyl-L-leucyl-L-seryl-L-histidyl-L-lysyl-glycyl-L-prolyl-L-methionyl-L-prolyl-L-phenylalanine. Grade: ≥95% by HPLC. CAS No. 252642-12-9. Molecular formula: C184H297N69O43S. Mole weight: 4195.87. | |
| Apelin-36 (rat, mouse) | Apelin-36 (rat, mouse) is an endogenous ligand of the G protein-coupled APJ receptor with EC50 value of 5.4 nM that is secreted by adipocytes. It potently inhibits cAMP production in vitro. It is important in regulating fluid homeostasis, cardiovascular function and feeding. It potently blocks HIV-1 and HIV-2 strains entry into cells expressing APJ and CD4 and limits HIV infection. Synonyms: Apelin-36 (rat, mouse); Apelin 36 (rat, mouse); Apelin36 (rat, mouse). Grade: 95%. CAS No. 230299-95-3. Molecular formula: C185H304N68O43S. Mole weight: 4200.93. | |
| APETx2 | APETx2, an ion channel 3 (ASIC3) channel blocker, has been found to exhibit analgesic properties against acid-induced and inflammatory pain. Synonyms: APETx2; 713544-47-9; AKOS024458355; H-Gly-DL-xiThr-DL-Ala-DL-Cys(1)-DL-Ser-DL-Cys(2)-Gly-DL-Asn-DL-Ser-DL-Lys-Gly-DL-xiIle-DL-Tyr-DL-Trp-DL-Phe-DL-Tyr-DL-Arg-DL-Pro-DL-Ser-DL-Cys(3)-DL-Pro-DL-xiThr-DL-Asp-DL-Arg-Gly-DL-Tyr-DL-xiThr-Gly-DL-Ser-DL-Cys(2)-DL-Arg-DL-Tyr-DL-Phe-DL-Leu-Gly-DL-xiThr-DL-Cys(1)-DL-Cys(3)-DL-xiThr-DL-Pro-DL-Ala-DL-Asp-OH. Grade: >98%. CAS No. 713544-47-9. Molecular formula: C196H280N54O61S6. Mole weight: 4561.06. | |
| APHE-3 | APHE-3 is a pyrazoloisoquinolinone antibiotic produced by Streptoverticillium griseocarneum. It has weak anti-Gram-positive bacteria activity. APHE-3 can also inhibit lymphocyte proliferation in the presence of Phytohemagglutinin, with IC50 of about 0.1 mmol/L. Synonyms: Pimprinine; WS 30581C. Grade: >95% by HPLC. CAS No. 13640-26-1. Molecular formula: C12H10N2O. Mole weight: 198.22. | |
| Aphidicolin | Aphidicolin is an antibiotic produced by Cephalosporium aphidicola and Nigrospora sphaerica, which has the effect of inhibiting mitosis and anti-DNA virus. Aphidicolin potentiates apoptosis induced by arabinosyl nucleosides in a human promyelocytic leukemia cell line. Uses: A reversible inhibitor of eukaryotic nuclear dna replication. Synonyms: (+)-Aphidicolin; (3R,4R,4aR,6aS,8R,9R,11aS,11bS)-4,9-bis(hydroxymethyl)-4,11b-dimethyltetradecahydro-8,11a-methanocyclohepta[a]naphthalene-3,9-diol. Grade: >98%. CAS No. 38966-21-1. Molecular formula: C20H34O4. Mole weight: 338.48. | |
| Apicidin | Apicidin is a cyclic peptide antibiotic with broad-spectrum antiproliferative, antiparasitic and antiprotozoan activity. It is a histone deacetylase (HDAC) inhibitor with anti-angiogenesis and apoptosis-inducing effects. Synonyms: OSI 2040; Cyclo[(2S)-2-amino-8-oxodecanoyl-1-methoxy-L-tryptophyl-L-isoleucyl-(2R)-2-piperidinecarbonyl]; Cyclo(8-oxo-L-2-aminodecanoyl-1-methoxy-L-tryptophyl-L-isoleucyl-D-2-piperidinecarbonyl); Apicidin Ia; 2H-Pyrido[1,2-a][1,4,7,10]tetraazacyclododecine-1,4,7,10(3H,12H)-tetrone, octahydro-6-[(1-methoxy-1H-indol-3-yl)methyl]-9-[(1S)-1-methylpropyl]-3-(6-oxooctyl)-, (3S,6S,9S,15aR)-. Grade: >98%. CAS No. 183506-66-3. Molecular formula: C34H49N5O6. Mole weight: 623.78. | |
| APN-C3-biotin | APN-C3-biotin is a heterobifunctional linker containing an APN moiety with exquisite chemoselectivity for cysteine and Biotin. The superior stability of APN-cysteine conjugates in aqueous media, human plasma, and living cells makes this new thiol-click reaction a promising methodology for applications in bioconjugation. Please contact us for GMP-grade inquiries. Synonyms: APN-C3-biotin; 2170240-97-6; CS-0254631; Rel-N-(4-((4-(cyanoethynyl)phenyl)amino)-4-oxobutyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide. Grade: 0.98. CAS No. 2170240-97-6. Molecular formula: C23H27N5O3S. Mole weight: 453.6. | |
| Apoptolidin | Apoptolidin is an apoptosis inducer produced by Nocardiopsis sp. Apoptolidin can induce apoptosis of metastatic cells, but has no effect on normal cells. Synonyms: (1R)-O-2,6-Dideoxy-3-O-methyl-β-D-arabino-hexopyranosyl-(1→4)-O-2,6-dideoxy-3-C-methyl-α-L-arabino-hexopyranosyl-(1→8)-3,5,7-trideoxy-1-C-[(2S,4S,5S,8E,10E,12R,13R,14E,16E,18E)-12-[(6-deoxy-4-O-methyl-α-L-glucopyranosyl)oxy]-5-hydroxy-4-methoxy-9,13,15,17,19-pentamethyl-20-oxooxacycloeicosa-8,10,14,16,18-pentaen-2-yl]-3,5-dimethyl-9-O-methyl-L-glycero-α-D-galacto-2-nonulopyranose; Apoptolidin A; FU 40A. Grade: ≥95%. CAS No. 194874-06-1. Molecular formula: C58H96O21. Mole weight: 1129.37. | |
| Apraglutide | Apraglutide is a synthetic long-acting GLP-2 analogue containing 33 amino acids that enhances the adaptation and linear intestinal growth of neonatal piglets in a model of short bowel syndrome with total ileal resection. Synonyms: FE 203799; His-Gly-Asp-Gly-Ser-Phe-Ser-Asp-Glu-Nle-D-Phe-Thr-Ile-Leu-Asp-Leu-Leu-Ala-Ala-Arg-Asp-Phe-Ile-Asn-Trp-Leu-Ile-Gln-Thr-Lys-Ile-Thr-Asp-NH2. Grade: ≥95%. CAS No. 1295353-98-8. Molecular formula: C172H263N43O52. Mole weight: 3765.25. | |
| Apramycin | Apramycin is an aminoglycoside antibiotic produced by Streptomyces tenebrarius. Apramycin has a broad antibacterial spectrum and has a strong effect on both Gram-positive and negative bacteria. Uses: Anti-bacterial agents. Synonyms: Nebramycin II; Nebramycin factor 2; Apramycinum; Apramicina; O-4-Amino-4-deoxy-α-D-glucopyranosyl-(1→8)-O-(8R)-2-amino-2,3,7-trideoxy-7-(methylamino)-D-glycero-α-D-allo-octodialdo-1,5:8,4-dipyranosyl-(1→4)-2-deoxy-D-streptamine; Ambylan; Apralan; Apralan 200 Injection; Apralin; EL 857; EL 857/820. Grade: >98%. CAS No. 37321-09-8. Molecular formula: C21H41N5O11. Mole weight: 539.58. | |
| Apramycin Sulfate | Apramycin is an aminoglycoside antibiotic produced by Streptomyces. It has activity against Gram-negative bacteria. It acts by blocking translocation and binding to the eukaryotic decoding site despite differences in key residues required for apramycin recognition by the bacterial target. Uses: Anti-bacterial agents. Synonyms: FEMA 2131; FEMA2131; FEMA-2131; D-Streptamine, O-4-amino-4-deoxy-α-D-glucopyranosyl-(1→8)-O-(8R)-2-amino-2,3,7-trideoxy-7-(methylamino)-D-glycero-α-D-allo-octodialdo-1,5:8,4-dipyranosyl-(1→4)-2-deoxy-, sulfate (1:x); D-Streptamine, O-4-amino-4-deoxy-α-D-glucopyranosyl-(1→8)-O-(8R)-2-amino-2,3,7-trideoxy-7-(methylamino)-D-glycero-α-D-allo-octodialdo-1,5:8,4-dipyranosyl-(1→4)-2-deoxy-, sulfate (salt); O-4-Amino-4-deoxy-α-D-glucopyranosyl-(1→8)-O-(8R)-2-amino-2,3,7-trideoxy-7-(methylamino)-D-glycero-α-D-allo-octodialdo-1,5:8,4-dipyranosyl-(1→4)-2-deoxy-D-streptamine sulfate; Nebramycin factor 2 sulfate. Grade: >98%. CAS No. 65710-07-8. Molecular formula: C21H41N5O11.xH2O4S. Mole weight: 539.58 (free base). | |
| Aprotinin | Aprotinin is the small protein bovine pancreatic trypsin inhibitor (BPTI). It is an antifibrinolytic molecule that inhibits trypsin and related proteolytic enzymes. It is a competitive serine protease inhibitor which blocks the active sites of enzyme by forming stable complexes with. It is a monomeric globular protein derived from bovine lung that consists of 58 amino acids, arranged in a single polypeptide chain with three crosslinking disulfide bridges. It is used as a medication administered by injection to reduce bleeding during complex surgery, such as heart and liver surgery. It is used clinically to prevent postoperative blood loss and reduce transfusion requirements in those procedures which employ extracorporeal circulation. It is also used as a protein purification tool to prevent proteases present in tissue samples from degrading the protein of interest. It was temporarily withdrawn worldwide in 2007. It was reverted its previous standpoint regarding aprotinin by the European Medicines Agency (EMA) scientific committee in February 2012. Uses: Aprotinin is used as medication administered by injection to reduce bleeding during complex surgery, such as heart and liver surgery. it is used clinically to prevent postoperative blood loss and reduce transfusion requirements in those procedures which employ extracorporeal circulation. it is also used as a protein purification tool to prevent proteases present in tissue sampleĀ | |
| Aquastatin A | Aquastatin A is an adenosine triphosphatase inhibitor produced by Fusariumaquaeductuum. Synonyms: 4-{[4-(Hexopyranosyloxy)-2-hydroxy-6-pentadecylbenzoyl]oxy}-2-hydroxy-6-methylbenzoic acid. CAS No. 153821-50-2. Molecular formula: C36H52O12. Mole weight: 676.79. | |
| Aranorosin | Aranorosin is a fungal metabolite originally isolated from P. roseus and an inhibitor of anti-apoptotic functions regulated by Bcl-2. It has antimicrobial activity against B. subtilis, A. niger, and C. albicans when used at a concentration of 1 mg/ml. Aranorosin also reduces viability in apoptosis-resistant HeLa/Bcl-2 cells. Aranorosin also inhibits enzyme AAC(6')/APH(2'') which plays a role in arbekacin (ABK)-resistance in MRSA. Synonyms: Spiro[4,8-dioxatricyclo[5.1.0.03,5]octane-2,2'(3'H)-furan], 2,4-dodecadienamide deriv.; Aranorosine. Grade: ≥95%. CAS No. 117184-53-9. Molecular formula: C23H33NO6. Mole weight: 419.51. | |
| Arbekacin | Arbekacin(INN) is a semisynthetic aminoglycoside antibiotic. It is primarily used for the treatment of infections caused by multi-resistant bacteria including methicillin-resistant Staphylococcus aureus(MRSA). Grade: >98%. CAS No. 51025-85-5. Molecular formula: C22H44N6O10. Mole weight: 552.31. | |
| Arbekacin sulfate | Arbekacin is a semi-synthetic aminoglycoside antibiotic used to treat infections caused by methicillin-resistant Staphylococcus aureus (MRSA). Synonyms: Habekacin. CAS No. 104931-87-5. Molecular formula: C22H46N6O14S. Mole weight: 650.70. | |
| (Arg8,des-Gly-NH29)-Vasopressin | (Arg8,des-Gly-NH29)-Vasopressin is an impurity of Vasopressin, which is an antidiuretic hormone secreted from the posterior pituitary. Synonyms: Des-Gly-OH-Vasopressin; H-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-OH (Disulfide bridge: Cys1-Cys6); L-cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-asparagyl-L-cysteinyl-L-prolyl-L-arginine (1->6)-disulfide; Des-Gly-OH-AVP; 9-Deglycinamide-argipressin; 9-des-GlyNH2-argipressin; 1-8-Vasopressin, 8-L-arginine-; 8-L-Arginine-1-8-vasopressin; Vasopressin, 8-L-arginine-9-deglycinamide-; 8-Arginine-9-deglycinamide-vasopressin; 8-Arginine-9-desglycinamide vasopressin; [Arg8,de-Gly9]-vasopressin; Org 5667; [Deglycinamide9,arginine8]-vasopressin; [Desglycinamide9-arginine8]-vasopressin; Arginine vasopressin-(1-8). Grade: ≥95% by HPLC. CAS No. 37552-33-3. Molecular formula: C44H61N13O12S2. Mole weight: 1028.17. | |
| (Arg8)-Vasopressin (free acid) | Gly-OH-AVP is an impurity of Vasopressin, which is an antidiuretic hormone secreted from the posterior pituitary. Synonyms: Gly 9-Vasopressin; Arg-Vasopressin-Acid; Gly-OH Vasopressin; L-cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-asparagyl-L-cysteinyl-L-prolyl-L-arginyl-glycine (1->6)-disulfide; Gly-OH Argipressin; Vasopressin, 8-L-arginine-9-glycine-; 8-L-Arginine-9-glycinevasopressin; (Arg8)-Vasopressinoic acid; [Arg8,Gly-OH9]vasopressin; Vasopressinoic acid; H-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly-OH (Disulfide bridge: Cys1-Cys6); Gly-OH-AVP. Grade: ≥95%. CAS No. 25255-33-8. Molecular formula: C46H64N14O13S2. Mole weight: 1085.23. | |
| [Arg8]-Vasotocin | [Arg8]-Angiotensin (AVT) is a neuropeptide peptide of the vasopressin/oxytocin hormone family, which has the function of regulating adrenal cortex hormones. Synonyms: H-Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Arg-Gly-NH2 (Disulfide bridge: Cys1-Cys6); Oxytocin, 8-L-arginine-; 1-9-Hydrin 2 (peptide), 9-glycinamide-; 8-L-Arginineoxytocin; 3-Isoleucine-8-arginine vasopressin; 8-L-Arginine-vasotocin; 8-Arginine oxytocin; 8-Arginine vasotocin; [Arg8]oxytocin; Arginine vasotocin; Arginine-vasotocin; Argiprestocin; Natriuretic hormone (ox pineal); Vasotocin (Neoceratodus forsteri); Vasotocin, 8-L-arginine-; L-cysteinyl-L-tyrosyl-L-isoleucyl-L-glutaminyl-L-asparagyl-L-cysteinyl-L-prolyl-L-arginyl-glycinamide (1->6)-disulfide. Grade: 95%. CAS No. 113-80-4. Molecular formula: C43H67N15O12S2. Mole weight: 1050.22. | |
| (Arg)9 | (Arg)9, also known as Nona-L-arginine or Peptide R9, is a cell-permeable peptide used for drug delivery with neuroprotective activity (IC50= 0.78 μM in the glutamic acid model). Synonyms: Nona-L-arginine; Peptide R9. Grade: 98%. CAS No. 143413-47-2. Molecular formula: C54H110N36O10. Mole weight: 1423.69. | |
| (Arg)9 biotin labeled | It is a cell penetrating peptide with nine arginines. It contains a biotin group that is attached to the epsilon amino group of lysine at the n-terminus. Synonyms: Biotin-LC-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-NH2. Grade: ≥95%. Mole weight: 1762.20. | |
| Arg-Glu(EDANS)-(Asn670,Leu671)-Amyloid β/A4 Protein Precursor770 (668-675)-Lys(DABCYL)-Arg | Arg-Glu(EDANS)-(Asn670,Leu671)-Amyloid β/A4 Protein Precursor770 (668-675)-Lys(DABCYL)-Arg, a fluorogenic (FRET) substrate for pro-memapsin-2, contains the β-secretase site EVNLDAEF of the Swedish mutation of APP. The kinetic parameters at pH 4.5 are Km = 5.4 μM and kcat = 0.24 min-1. Synonyms: Arg-Glu(EDANS)-(Asn670,Leu671)-APP770 (668-675)-Lys(DABCYL)-Arg; H-Arg-Glu(EDANS)-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Lys(DABCYL)-Arg-OH. Grade: 95%. CAS No. 310427-94-2. Molecular formula: C91H129N25O25S. Mole weight: 2005.22. | |
| Arg-Gly-Asp-Ser | Arg-Gly-Asp-Ser is an integrin binding sequence that inhibits integrin receptor function. It is a tetrapeptide found on fibronectin, fibrinogen α, and von Willebrand factor, but not vitronectin or collagen. It decreases systemic inflammation via inhibition of collagen-triggered activation of leukocytes and attenuates expression of inflammatory cytokines, iNOS and MMP-9. It inhibits thrombin-induced binding of platelets to fibronectin, fibrinogen α, and von Willebrand factor. It promotes cell attachment and abrogates apoptosis via the mitochondrial pathway in osteoblasts in vitro. It also blocks the attachment of certain pathogens to cells. Uses: Platelet aggregation inhibitors. Synonyms: Arg Gly Asp Ser; RGDS peptide; Fibronectin Inhibitor. Grade: >98%. CAS No. 91037-65-9. Molecular formula: C15H27N7O8. Mole weight: 433.42. | |
| Argipressin | This molecular is a polypeptide which is a Antidiuretic hormone that has been found in most mammalian species and it acts as a neurotransmitter at synapses in the brain to increases[Ca2+]i in cultured rat hippocampal neurons. In the Past, Arg-vasopressin was applicated to treat diabetes insipidus or to improve vasomotor tone and blood pressure. In 2008, preclinical trials in Heart was failed in USA (Intranasal). Uses: Treat diabetes insipidus or to improve vasomotor tone and blood pressure. Synonyms: Vasopressin; Arg8-vasopressin; AVP; H-Cys(1)-Tyr-Phe-Gln-Asn-Cys(1)-Pro-Arg-Gly-NH2. Grade: 95%. CAS No. 113-79-1. Molecular formula: C46H65N15O12S2. Mole weight: 1084.23. | |
| Argipressin Acetate | Argipressin Acetate is an antidiuretic hormone secreted from the posterior pituitary. Argipressin acts via V1A receptors in blood vessels, causing vasoconstriction, and via V2 receptors in the renal tubules, causing anti-diuresis. Synonyms: Argipressin monoacetate; (Cys-Tyr-Phe-Gln-Asn-Cys)Cycl-Pro-Arg-Gly-NH2 acetate salt; Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly-NH2 acetate salt; Antidiuretic hormone acetate salt; Arginine vasopressin acetate salt; [ARG8]-vasopressin acetate salt. Grade: 98%. CAS No. 129979-57-3. Molecular formula: C48H69N15O14S2. Mole weight: 1144.28. | |
| [Arg(Me2s)3]-Histone H4 (1-21)-Gly-Gly-Lys(biotinyl) | [Arg(Me2s)3]-Histone H4 (1-21)-Gly-Gly-Lys(biotinyl) is a derivative of Histone H4, a fundamental unit of chromatin. Synonyms: Ac-Ser-Gly-Arg(Me2)-Gly-Lys-Gly-Gly-Lys-Gly-Leu-Gly-Lys-Gly-Gly-Ala-Lys-Arg-His-Arg-Lys-Val-Gly-Gly-Lys(Biotin)-OH. Molecular formula: C111H197N43O29S. Mole weight: 2630.1. | |
| Aristeromycin | Aristeromycin is a nucleoside antibiotic produced by Streptomyces citricolor. It has a minimum inhibitory concentration of 5 mg/mL against Xanthomonas oryzae and Pear. Synonyms: Cycloadenosine; (1R,2S,3R,5R)-3-(6-amino-9H-purin-9-yl)-5-(hydroxymethyl)cyclopentane-1,2-diol. CAS No. 19186-33-5. Molecular formula: C11H15N5O3. Mole weight: 265.27. | |
| AR-M 1896 acetate | AR-M 1896 acetate is the selective galanin GAL2 receptor agonist used as an antiepileptogenic agent. Synonyms: H-Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-NH2.CH3CO2H; L-tryptophyl-L-threonyl-L-leucyl-L-asparagyl-L-seryl-L-alanyl-glycyl-L-tyrosyl-L-leucyl-L-leucinamide acetic acid. Grade: ≥95%. Molecular formula: C56H85N13O16. Mole weight: 1196.35. | |
| Arphamenine A | Arphamenine A is an enzyme inhibitor produced by Chromobacteriuin violaceum HMG361-CF4. It can inhibit the activity of aminopeptidase B, and can inhibit sarcoma 180 and IMC cancer. Synonyms: Benzenepropanoic acid, α-[(3S)-3-amino-6-[(aminoiminomethyl)amino]-2-oxohexyl]-, (αR)-; (αR)-α-[(3S)-3-Amino-6-[(aminoiminomethyl)amino]-2-oxohexyl]benzenepropanoic acid; Benzenepropanoic acid, α-[3-amino-6-[(aminoiminomethyl)amino]-2-oxohexyl]-, [S-(R*,S*)]-; Arphamenin A. Grade: ≥95%. CAS No. 96551-81-4. Molecular formula: C16H24N4O3. Mole weight: 320.39. | |
| Arphamenine B hydrochloride | Arphamenine B is an enzyme inhibitor produced by Chromobacteriuin violaceum HMG361-CF4. It can inhibit the activity of aminopeptidase B, and can inhibit sarcoma 180 and IMC cancer. Synonyms: Benzenepropanoic acid, α-[3-amino-6-[(aminoiminomethyl)amino]-2-oxohexyl]-4-hydroxy-, monohydrochloride, [S-(R*,S*)]-; Arphamenine B monohydrochloride; Benzenepropanoic acid, α-[(3S)-3-amino-6-[(aminoiminomethyl)amino]-2-oxohexyl]-4-hydroxy-, (αR)-, monohydrochloride; (αR)-α-[(3S)-3-Amino-6-[(aminoiminomethyl)amino]-2-oxohexyl]-4-hydroxybenzenepropanoic acid monohydrochloride. Grade: ≥95%. CAS No. 88465-81-0. Molecular formula: C16H24N4O4.HCl. Mole weight: 372.85. | |
| Ascamycin | Ascamycin is a 5'-O-sulfonamide ribonucleoside antibiotic produced by Streptomyces sp. JCM9888. The MIC values of Ascamycin against Xanthomonas citri, Xanthomonas oryzae and Mycobacterium phlei are 0.4 μg/mL, 12.5 μg/mL and 12.5 μg/mL, respectively. Synonyms: (+)-5'-O-[[(S)-2-Amino-1-oxopropyl]aminosulfonyl]-2-chloroadenosine; 2-Chloro-5'-O-[(L-alanylamino)sulfonyl]adenosine; 2-Chloro-5'-O-[[(S)-2-amino-1-oxopropyl]sulfamoyl]adenosine; 5'-O-{[(2S)-2-Amino-1-hydroxypropylidene]sulfamoyl}-2-chloroadenosine. Grade: ≥95%. CAS No. 91432-48-3. Molecular formula: C13H18ClN7O7S. Mole weight: 451.84. | |
| Ascochlorin | Ascochlorin is an antibiotic produced by Ascochyta viciae. It has anti-candida albicans activity. It can inhibit Newcastle disease virus and herpes simplex virus plaque formation in chicken embryo fibroblast culture. Synonyms: Ilicicolin D. Grade: >98%. CAS No. 26166-39-2. Molecular formula: C23H29ClO4. Mole weight: 404.93. | |
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