BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| ABZ-TBU-GLY-TBU-GLY-ASN(ME)2-ALA-SER-SER-ARG-LEU-3-NITRO-TYR-ARG-OH | ABZ-TBU-GLY-TBU-GLY-ASN(ME)2-ALA-SER-SER-ARG-LEU-3-NITRO-TYR-ARG-OH. Synonyms: ABZ-TBU-GLY-TBU-GLY-ASN(ME)2-ALA-SER-SER-ARG-LEU-3-NITRO-TYR-ARG-OH; H-2-ABZ-TBU-GLY-TBU-GLY-ASN(ME)2-ALA-SER-SER-ARG-LEU-3-NITRO-TYR-ARG-OH; 2-AMINOBENZOYL (ANTHRANILOYL)-*TERT-BUTYL-GLY-ASN(M; anthraniloyl-gly(t-butyl)-asn(methyl)2-ala-ser-ser-arg-leu-3-n. CAS No. 204909-37-5. Molecular formula: C61H97N19O18. Mole weight: 1384.54. |  |
| Abz-Val-Ala-Asp-Nva-Arg-Asp-Arg-Gln-EDDnp | Abz-Val-Ala-Asp-Nva-Arg-Asp-Arg-Gln-EDDnp is a fluorescence-quenching substrate for Human Neutrophil Proteinase 3. Synonyms: N-(2-aminobenzoyl)-L-valyl-L-alanyl-L-alpha-aspartyl-L-norvalyl-L-arginyl-L-alpha-aspartyl-L-arginyl-N1-[2-[(2,4-dinitrophenyl)amino]ethyl]-L-glutamamide. CAS No. 1042405-14-0. Molecular formula: C53H80N20O18. Mole weight: 1285.33. | |
| AC 187 | AC 187 is a potent amylin receptor antagonist (IC50 = 0.48 nM) displaying 38- and 400-fold selectivity over calcitonin and CGRP receptors respectively. It inhibits amyloid β-induced neurotoxicity by attenuating the activation of initiator and effector caspases in vitro. It increases glucagon secretion, accelerates gastric emptying, alters plasma glucose levels and increases food intake in vivo. Synonyms: Ac-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asn-Thr-Gly-Ser-Asn-Thr-Tyr-NH2; N-acetyl-L-valyl-L-leucyl-glycyl-L-lysyl-L-leucyl-L-seryl-L-glutaminyl-L-alpha-glutamyl-L-leucyl-L-histidyl-L-lysyl-L-leucyl-L-glutaminyl-L-threonyl-L-tyrosyl-L-prolyl-L-arginyl-L-threonyl-L-asparagyl-L-threonyl-glycyl-L-seryl-L-asparagyl-L-threonyl-L-tyrosinamide; AC187; salmon calcitonin (8-32) reduced; acetyl-(Asn30,Tyr32)sCT(8-37); AC-187. Grade: >98%. CAS No. 151804-77-2. Molecular formula: C127H205N37O40. Mole weight: 2890.25. | |
| AC 187 acetate | AC 187 acetate is a potent amylin receptor antagonist (IC50 = 0.48 nM) displaying 38- and 400-fold selectivity over calcitonin and CGRP receptors respectively. It inhibits amyloid β-induced neurotoxicity by attenuating the activation of initiator and effector caspases in vitro. It increases glucagon secretion, accelerates gastric emptying, alters plasma glucose levels, and increases food intake in vivo. Synonyms: Ac-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asn-Thr-Gly-Ser-Asn-Thr-Tyr-NH2.CH3CO2H; N-acetyl-L-valyl-L-leucyl-glycyl-L-lysyl-L-leucyl-L-seryl-L-glutaminyl-L-alpha-glutamyl-L-leucyl-L-histidyl-L-lysyl-L-leucyl-L-glutaminyl-L-threonyl-L-tyrosyl-L-prolyl-L-arginyl-L-threonyl-L-asparagyl-L-threonyl-glycyl-L-seryl-L-asparagyl-L-threonyl-L-tyrosinamide acetic acid. Grade: ≥95%. Molecular formula: C129H209N37O42. Mole weight: 2950.26. | |
| Ac2-26 | Ac2-26 is an annexin/lipocortin 1-mimetic peptide that inhibits leukocyte extravasation. It promotes detachment of neutrophils from activated mesenteric endothelium and accelerates epithelial wound repair after induced colonic injury in mice in vivo. It reduces neutrophil adhesion and emigration. It has an anti-inflammatory effect. Synonyms: Annexin-1 (2-26) (human); Ac2-26; Lipocortin-1 (2-26); Calpactin II (1-25) (dephosphorylated) (human); Annexin A1 (1-25) (dephosphorylated) (human); Annexin A1 (1-25) (dephosphorylated) (human); Ac-Ala-Met-Val-Ser-Glu-Phe-Leu-Lys-Gln-Ala-Trp-Phe-Ile-Glu-Asn-Glu-Glu-Gln-Glu-Tyr-Val-Gln-Thr-Val-Lys-OH. Grade: >98%. CAS No. 151988-33-9. Molecular formula: C141H210N32O44S. Mole weight: 3089.43. | |
| Ac9-25 | Ac9-25 is a N-terminal peptide of Annexin I (AI/Lipocortin I) that inhibits leukocyte extravasation. It stimulates neutrophil NADPH oxidase activation by acting as a formyl peptide receptor 1 (FPR1) ligand. Synonyms: L-Lysine, N2-acetyl-L-glutaminyl-L-alanyl-L-tryptophyl-L-phenylalanyl-L-isoleucyl-L-α-glutamyl-L-asparaginyl-L-α-glutamyl-L-α-glutamyl-L-glutaminyl-L-α-glutamyl-L-tyrosyl-L-valyl-L-glutaminyl-L-threonyl-L-valyl-; N2-Acetyl-L-glutaminyl-L-alanyl-L-tryptophyl-L-phenylalanyl-L-isoleucyl-L-α-glutamyl-L-asparaginyl-L-α-glutamyl-L-α-glutamyl-L-glutaminyl-L-α-glutamyl-L-tyrosyl-L-valyl-L-glutaminyl-L-threonyl-L-valyl-L-lysine; Ac-Gln-Ala-Trp-Phe-Ile-Glu-Asn-Glu-Glu-Gln-Glu-Tyr-Val-Gln-Thr-Val-Lys-OH. Grade: ≥95%. CAS No. 284040-76-2. Molecular formula: C99H143N23O33. Mole weight: 2183.35. | |
| Acarbose | Acarbose is an inhibitor of alpha-glucosidase isolated from Actinoplance sp., used to treat type 2 diabetes. Uses: Enzyme inhibitors; hypoglycemic agents. Synonyms: Amylostatin J; Bay g 5421; α-GHI; Glucobay; 4,6-dideoxy-4-{[(1S,4S,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranosyl-(1→4)-alpha-D-glucopyranosyl-(1→4)-beta-D-glucopyranose. Grade: >95% by HPLC. CAS No. 56180-94-0. Molecular formula: C25H43NO18. Mole weight: 645.61. | |
| Ac-Arg-Cys-Met-5-aminopentanoyl-Arg-Val-Tyr-5-aminopentanoyl-Cys-NH2, (Disulfide bond) | Ac-Arg-Cys-Met-5-aminopentanoyl-Arg-Val-Tyr-5-aminopentanoyl-Cys-NH2 is a full competitive MCH-1 receptor antagonist and has no agonist effect on human MCH-1 receptor even at micromolar concentrations (Kb = 3.6 nM). Synonyms: Ac-Arg-Cys-Met-Ava-Arg-Val-Tyr-Ava-Cys-NH2 (Disulfide bridge: Cys2-Cys9); L-Cysteinamide, N2-acetyl-L-arginyl-L-cysteinyl-L-methionyl-5-aminopentanoyl-L-arginyl-L-valyl-L-tyrosyl-5-aminopentanoyl-, cyclic (2→9)-disulfide. Grade: ≥95%. CAS No. 353487-64-6. Molecular formula: C49H82N16O11S3. Mole weight: 1167.49. | |
| Ac-DEVD-CHO | Ac-DEVD-CHO is a potent aldehyde inhibitor of Group II caspases with Ki values of 0.2 nM and 0.3 nM for for caspase-3 and caspase-7, respectively. Weak inhibition for caspase-2. Uses: Cysteine proteinase inhibitors. Synonyms: N-acetyl-asp-glu-val-asp-al; Ac-Asp-Glu-Val-Asp-Aldehyde; L-Valinamide,N-acetyl-L-a-aspartyl-L-a-glutamyl-N-(2-carboxy-1-formylethyl)-. Grade: 95 %. CAS No. 169332-60-9. Molecular formula: C20H30N4O11. Mole weight: 502.47. | |
| Ac-DEVD-CHO acetate | Ac-DEVD-CHO acetate is a specific inhibitor of Caspase-3. Synonyms: Caspase-3 Inhibitor I; N-acetyl-asp-glu-val-asp-al acetate; Ac-Asp-Glu-Val-Asp-al acetate; Ac-DEVD-al.CH3CO2H; L 761191 acetate; MF 191 acetate; N-acetyl-L-alpha-aspartyl-L-alpha-glutamyl-L-valyl-L-aspart-1-al acetate; N-Acetyl-L-α-aspartyl-L-α-glutamyl-N-[(1S)-2-carboxy-1-formylethyl]-L-valinamide acetate. Grade: ≥95%. Molecular formula: C22H34N4O13. Mole weight: 562.52. | |
| Ac-DEVD-CMK | Ac-DEVD-CMK is a cell-permeable, and irreversible inhibitor of caspase-3 as well as caspase-6, -7, -8, and -10. It is commonly used at concentrations up to 100 μM to examine the role of caspase-3-dependent apoptosis in biological systems. Synonyms: Ac-Asp-Glu-Val-Asp-chloromethylketone; Caspase-3 Inhibitor III; N-acetyl-Asp-Glu-Val-Asp-chloromethylketone; N-Acetyl-L-α-aspartyl-L-α-glutamyl-N-[(2S)-1-carboxy-4-chloro-3-oxo-2-butanyl]-L-valinamide; (2S,5S,8S,11S)-8-(2-carboxyethyl)-11-(carboxymethyl)-2-(2-chloroacetyl)-5-isopropyl-4,7,10,13-tetraoxo-3,6,9,12-tetraazatetradecane-1-carboxylic acid. Grade: ≥98%. CAS No. 285570-60-7. Molecular formula: C21H31ClN4O11. Mole weight: 550.95. | |
| Ac-DL-Leu-OH | Acetylleucine is a drug mianly used to treat the vertigo.It has been listed. Uses: Acetylleucine is used to treat the vertigo. Synonyms: Acetylleucine; N-Acetyl-DL-leucine; DL-Leucine,N-acetyl-; Acetyl-DL-leucine; Tanganil; 2-Acetamido-4-methylpentanoic acid. Grade: >98 %. CAS No. 99-15-0. Molecular formula: C8H15NO3. Mole weight: 173.21. | |
| Aceglutamide | Aceglutamide, also called as Glumal or acetylglutamine, is able to improve memory and concentration as psychostimulant and nootropic. Synonyms: NSC 186896; NSC-186896; NSC186896; N(sup2)-Acetyl-L-glutamine; (2S)-2-acetamido-5-amino-5-oxopentanoic acidaceglutamideaceglutamide, aluminum (3:1) saltN-acetyl-L-glutamineN-acetylglutamine. Grade: 95%. CAS No. 2490-97-3. Molecular formula: C7H12N2O4. Mole weight: 188.18. | |
| Acein | Acein is a high-affinity angiotensin-converting enzyme (ACE) ligand with a Kd of 2.79 nM. It potentiates NMDA+ D-serine-induced dopamine release from the striatum in vivo and striatal slices in vitro. Synonyms: L-Alanine, L-prolyl-L-prolyl-L-threonyl-L-threonyl-L-threonyl-L-lysyl-L-phenylalanyl-L-alanyl-; L-Prolyl-L-prolyl-L-threonyl-L-threonyl-L-threonyl-L-lysyl-L-phenylalanyl-L-alanyl-L-alanine; H-Pro-Pro-Thr-Thr-Thr-Lys-Phe-Ala-Ala-OH. Grade: ≥95%. CAS No. 2022202-76-0. Molecular formula: C43H68N10O13. Mole weight: 933.06. | |
| Acein acetate | Acein acetate is a high-affinity angiotensin-converting enzyme (ACE) ligand with a Kd of 2.79 nM. It potentiates NMDA+ D-serine-induced dopamine release from the striatum in vivo and striatal slices in vitro. Synonyms: H-Pro-Pro-Thr-Thr-Thr-Lys-Phe-Ala-Ala-OH.CH3CO2H; L-prolyl-L-prolyl-L-threonyl-L-threonyl-L-threonyl-L-lysyl-L-phenylalanyl-L-alanyl-L-alanine acetate. Grade: ≥95%. Molecular formula: C45H72N10O15. Mole weight: 993.11. | |
| Acetamide | Acetamide is the simplest amide derived from acetic acid. It finds some use as a plasticizer and as an industrial solvent. Acetamide (2.88 g/kg/d) can reduce central nervous lesions, but the efficacy is not improved after increasing the dose. Synonyms: Ethanamide; Acetic Acid Amide; Methanecarboxamide; Acetimidic Acid; Amide C2. Grade: > 98 %. CAS No. 60-35-5. Molecular formula: C2H5NO. Mole weight: 59.07. | |
| Acetomycin | Acetomycin is an anti-human tuberculosis and amoeba antibiotic isolated from the Streptomyces ramnlosus. Acetomycin is an anti-biotic, anti-fungal, anti-protozoal, and anti-bacterial agent. Synonyms: (3S,4S,5R)-3-Acetyl-5-(acetyloxy)dihydro-3,4-dimethyl-2(3H)-furanone; (-)-Acetomycin; NSC 350598; [3S-(3α,4α,5α)]-3-acetyl-5-(acetyloxy)dihydro-3,4-dimethyl-2(3H)-furanone. Grade: 98%. CAS No. 510-18-9. Molecular formula: C10H14O5. Mole weight: 214.21. | |
| Acetyl-Amylin (8-37) (human) | Acetyl-Amylin (8-37) (human) is a most effective amylin antagonist, but its ability to block CGRP inhibition is limited. It completely reverses the inhibitory effect of IAPP on 14C-glycogen accumulation in vitro. Synonyms: Ac-Ala-Thr-Gln-Arg-Leu-Ala-Asn-Phe-Leu-Val-His-Ser-Ser-Asn-Asn-Phe-Gly-Ala-Ile-Leu-Ser-Ser-Thr-Asn-Val-Gly-Ser-Asn-Thr-Tyr-NH2; N-acetyl-L-alanyl-L-threonyl-L-glutaminyl-L-arginyl-L-leucyl-L-alanyl-L-asparagyl-L-phenylalanyl-L-leucyl-L-valyl-L-histidyl-L-seryl-L-seryl-L-asparagyl-L-asparagyl-L-phenylalanyl-glycyl-L-alanyl-L-isoleucyl-L-leucyl-L-seryl-L-seryl-L-threonyl-L-asparagyl-L-valyl-glycyl-L-seryl-L-asparagyl-L-threonyl-L-tyrosinamide. Grade: ≥95%. CAS No. 178603-79-7. Molecular formula: C140H218N42O46. Mole weight: 3225.53. | |
| Acetyl Angiotensinogen (1-14), porcine | Acetyl-angiotensinogen (1-14), porcine is encoded by the angiotensinogen gene and is known as a pre-angiotensinogen or angiotensinogen precursor. Synonyms: Angiotensinogen (tetradecapeptide renin substrate), N-acetyl-5-L-isoleucine-; Ac-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu-Leu-Val-Tyr-Ser-OH; N-acetyl-L-alpha-aspartyl-L-arginyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-prolyl-L-phenylalanyl-L-histidyl-L-leucyl-L-leucyl-L-valyl-L-tyrosyl-L-serine. Grade: 95%. CAS No. 66641-26-7. Molecular formula: C87H125N21O21. Mole weight: 1801.05. | |
| Acetyl Angiotensinogen (1-14), porcine acetate | Acetyl-angiotensinogen (1-14), porcine acetate is encoded by the angiotensinogen gene and is known as a pre-angiotensinogen or angiotensinogen precursor. Synonyms: Ac-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu-Leu-Val-Tyr-Ser-OH.CH3CO2H; N-acetyl-L-alpha-aspartyl-L-arginyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-prolyl-L-phenylalanyl-L-histidyl-L-leucyl-L-leucyl-L-valyl-L-tyrosyl-L-serine acetic acid. Grade: ≥95%. CAS No. 2918768-06-4. Molecular formula: C87H125N21O21.C2H4O2. Mole weight: 1861.11. | |
| Acetylaszonalenin | Acetylaszonalenin is a fungal metabolite that has been found in A. flavipes. It acts as an antagonist of neurokinin-1 (NK1) receptor. Synonyms: 2-acetoxy-n,n,n-trimethylethanaminium iodide; (+)-Acetylaszonalenin; (5aS,13aR,14aS)-5-acetyl-14a-(1,1-dimethyl-2-propen-1-yl)-5a,13a,14,14a-tetrahydro-indolo[3',2':4,5]pyrrolo[2,1-c][1,4]benzodiazepine-7,13(5H,12H)-dione; LL-S490β; Antibiotic LL-S490β. Grade: ≥95%. CAS No. 42230-55-7. Molecular formula: C25H25N3O3. Mole weight: 415.48. | |
| Acetylcysteine Impurity D | N,S-Diacetyl-L-cysteine is a double-prodrugs of L-cysteine: differential protection against acetaminophen-induced hepatotoxicity in mice. Synonyms: N,S-Diacetyl-L-cysteine; N-Acetylcysteine Acetate; Dacisteine; N,S-Diacetylcysteine; N-Acetylcysteine S-Acetate. Grade: > 95%. CAS No. 18725-37-6. Molecular formula: C7H11NO4S. Mole weight: 205.23. | |
| Acetyl-(D-Arg10,Cys11,D-Phe14,Cys17)-β-MSH (10-17) amide | Acetyl-(D-Arg10,Cys11,D-Phe14,Cys17)-β-MSH (10-17) amide, a selective and highly potent β-MSH-derived melanocortin-4 receptor (MC-4R) agonist, has sub-nanomolar potency with the binding affinities of 0.55±0.06, 16.78±1.53, 56.79±4.66 and <500 nM for human MC-4R, MC-1R, MC-3R and MC-5R, respectively. Synonyms: Ac-D-Arg-Cys-Glu-His-D-Phe-Arg-Trp-Cys-NH2 (Disulfide bridge: Cys2-Cys8); N-acetyl-D-arginyl-L-cysteinyl-L-alpha-glutamyl-L-histidyl-D-phenylalanyl-L-arginyl-L-tryptophyl-L-cysteinamide (2->8)-disulfide; 3-[(4R,7S,10S,13R,16S,19S,22R)-22-{[N2-Acetyl-N5-(diaminomethylene)-D-ornithyl]amino}-13-benzyl-4-carbamoyl-10-{3-[(diaminomethylene)amino]propyl}-16-(1H-imidazol-5-ylmethyl)-7-(1H-indol-3-ylmethyl)-6,9,12,15,18,21-hexaoxo-1,2-dithia-5,8,11,14,17,20-hexaazacyclotricosan-19-yl]propanoic acid; L-Cysteinamide, N2-acetyl-D-arginyl-L-cysteinyl-L-α-glutamyl-L-histidyl-D-phenylalanyl-L-arginyl-L-tryptophyl-, cyclic (2→8)-disulfide. Grade: ≥95%. CAS No. 819048-44-7. Molecular formula: C51H70N18O11S2. Mole weight: 1175.36. | |
| Acetyl-γ-aminobutyric acid | 4-Acetamidobutanoic acid is the main metabolite of GABA. 4-Acetamidobutanoic acid exhibits antioxidant and antibacterial activities. Synonyms: Ac-γ-Abu-OH; Acetyl-4-aminobutyric acid; 4-(Acetylamino)butanoic acid; N-Acetyl-4-aminobutyric acid; N-Acetyl-4-aminobutanoic acid; 4-Acetamidobutanoate; N-Acetyl-gamma-aminobutyrate; gamma-Acetylaminobutyric acid; DF 469; NSC 27423; N4-Acetylaminobutanoate. Grade: ≥ 95% (HPLC). CAS No. 3025-96-5. Molecular formula: C6H11NO3. Mole weight: 145.16. | |
| Acetyl-Heme-Binding Protein 1 (1-21) (human) | Acetyl-Heme-Binding Protein 1 (1-21) (human), an acetylated peptide corresponding to the N-terminal fragment of human heme-binding protein, specifically promotes calcium mobilization and chemotaxis in dendritic cells and monocytes via the FPR-like receptor 2 (FPRL 2). In neutrophils, it inhibits FPR and FPRL1-mediated signaling. Synonyms: F2L; Ac-Met-Leu-Gly-Met-Ile-Lys-Asn-Ser-Leu-Phe-Gly-Ser-Val-Glu-Thr-Trp-Pro-Trp-Gln-Val-Leu-OH; N-acetyl-L-methionyl-L-leucyl-glycyl-L-methionyl-L-isoleucyl-L-lysyl-L-asparagyl-L-seryl-L-leucyl-L-phenylalanyl-glycyl-L-seryl-L-valyl-L-alpha-glutamyl-L-threonyl-L-tryptophyl-L-prolyl-L-tryptophyl-L-glutaminyl-L-valyl-L-leucine. Grade: ≥95%. CAS No. 946571-77-3. Molecular formula: C116H176N26O30S2. Mole weight: 2478.96. | |
| Acetyl hexapeptide-3 | Acetyl hexapeptide-3 is a synthetic peptide that mimics the N-terminal of SNAP-25 (a substrate of Botulinum toxin (Botox)) protein and consists of six amino acids. A cosmetic formulation acts as an anti-wrinkle ingredient used in anti-aging products. Synonyms: N-Acetyl-L-α-glutamyl-L-α-glutamyl-L-methionyl-L-glutaminyl-L-arginyl-L-argininamide; Acetyl hexapeptide 8; Argireline; Argireline NP. Grade: ≥98%. CAS No. 616204-22-9. Molecular formula: C34H60N14O12S. Mole weight: 888.99. | |
| Acetyl-(N-Me-Leu17,N-Me-Phe19)-Amyloid β-Protein (16-20) amide | Acetyl-(N-Me-Leu17,N-Me-Phe19)-Amyloid β-Protein (16-20) amide is a membrane-permeable inhibitor of Aβ (1-40) fibrillogenesis. Synonyms: Ac-Lys-(NMe)Leu-Val-(NMe)Phe-Phe-NH2; N2-Acetyl-L-lysyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-phenylalanyl-L-phenylalaninamide; L-Phenylalaninamide, N2-acetyl-L-lysyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-phenylalanyl-. Grade: ≥95%. CAS No. 461640-33-5. Molecular formula: C39H59N7O6. Mole weight: 721.94. | |
| Acetyloxycycloheximide | Acetyloxycycloheximide is originally isolated from Streptomyces albulus ACTT 12757. When the concentration was 0.05-0.25 mg/kg, it could inhibit sarcoma 180 in mice, and its antifungal and antiyeast activities were very weak. Synonyms: E-73 acetate; Acetoxycycloheximide; Streptovitacin E 73; NSC 32743; Antibiotic E-73; 3-(2-(5-Acetoxy-3,5-dimethyl-2-oxocyclohexyl)-2-hydroxyethyl)glutarimide. Grade: >98%. CAS No. 2885-39-4. Molecular formula: C17H25NO6. Mole weight: 339.38. | |
| Acetyl Pepstatin | Acetyl Pepstatin is a high affinity HIV-1 protease inhibitor and aspartic protease inhibitor. It inhibits HIV-1 protease with Ki value of 20 nM at pH 4.7 and HIV-2 protease with Ki value of 5 nM at pH 4.7. It is used as an antiviral agent. Synonyms: Ac-Pepstatin; [1S-[1R*,2R*,4[R*[R*(R*)]]]]-1-(2-Methylpropyl)-4-oxobutyl]-N-acetyl-L-valyl-N-[4-[[2-[[1-(2-carboxy-1-hydroxyethyl)-3-methylbutyl]amino]-1-methyl-2-oxoethyl]amino]-2-hydroxy-L-valinamide; Pepsin Inhibitor S-PI-D (8CI); N-Acetyl-L-valyl-L-valyl-(3S,4S)-4-amino-3-hydroxy-6- methylheptanoyl-N-[(1S)-1-[(1S)-2-carboxy-1-hydroxyethyl]-3-methylbutyl]-L-alaninamide; Pepsidin C; S-PI; (4S,7S,8S,10S,19S)-8-carbamoyl-11,19-dihydroxy-10,18-diisobutyl-4-isopropyl-7,15-dimethyl-2,5,13,16-tetraoxo-3,9,14,17-tetraazahenicosan-21-oic acid. Grade: >98%. CAS No. 11076-29-2. Molecular formula: C31H57N5O9. Mole weight: 643.81. | |
| Acetyl-(Pro18,Asp21)-Amyloid β-Protein (17-21) amide | Acetyl-(Pro18,Asp21)-Amyloid β-Protein (17-21) amide is an analog of product H-4876 with small chemical modifications which enhance its stability against proteolytic degradation. It is a β-sheet breaker peptide that crosses the blood-brain barrier faster than most known proteins and peptides selectively absorbed by the brain, so it is assumed that the peptide is specifically transported to the brain. Synonyms: iAβ5p; Ac-LPFFD-NH2; N-acetyl-L-leucyl-L-prolyl-L-phenylalanyl-L-phenylalanyl-L-isoasparagine; L-α-Asparagine, N-acetyl-L-leucyl-L-prolyl-L-phenylalanyl-L-phenylalanyl-. Grade: ≥95%. CAS No. 339990-02-2. Molecular formula: C35H46N6O8. Mole weight: 678.78. | |
| Acetylspiramycin | It is a macrolide antibiotic produced by the strain of Str. ambofaciens. It has strong anti-gram-positive bacteria activity, but has weak anti-Gram-negative bacteria and mycobacteria activity. Its antibacterial activity is close to other components. It has partial cross-resistance with erythromycin, carbomycin and picromycin. Its activity is stronger in alkaline condition, and it is more active in vivo than in vitro. It is also effective against scrub typhus fever and rickettsia. Synonyms: Spiramycin II; 9-O-[(2R,5S,6R)-5-(Dimethylamino)tetrahydro-6-methyl-2H-pyran-2-yl]-3-acetate-leucomycin V; foromacidin B; spiramycin 2; spiramycin B; Leucomycin V, 9-O-[(2R,5S,6R)-5-(dimethylamino)tetrahydro-6-methyl-2H-pyran-2-yl]-3-acetate. Grade: ≥98%. CAS No. 24916-51-6. Molecular formula: C45H76N2O15. Mole weight: 885.09. | |
| Ac-FLTD-CMK | Ac-FLTD-CMK is a potent and selective inhibitor of caspases 1, 5 and 4 (IC50 values = 46.7 nM, 0.33 μM, 1.49 μM, respectively) that inhibits gasdermin D (GSDMD) cleavage. Synonyms: N-acetyl-Phe-Leu-Thr-Asp-chloromethylketone. Grade: 98%. CAS No. 2376255-48-8. Molecular formula: C26H37ClN4O8. Mole weight: 569.05. | |
| Ac-IEPD-AFC | Ac-IEPD-AFC is a peptide whose sequence is preferred recognition motif for the serine protease granzyme B. It is a fluorogenic substrate. Synonyms: IEPD; N-Acetyl-Ile-Glu-Pro-Asp-(7-amino-4-trifluoromethylcoumarin); Ac-Ile-Glu-Pro-Asp-7-Amino-4-trifluoromethylcoumarin. Grade: ≥95%. CAS No. 1135417-31-0. Molecular formula: C32H38F3N5O11. Mole weight: 725.67. | |
| Acivicin | Acivicin is an isoxazole antibiotic isolated from Streptomyces. sviceus. Acivicin is a glutamine analog that irreversibly inhibits glutamine-dependent amidotransferases involved in nucleotide and amino acid biosynthesis (Kis = 10 and 560 μM for anthranilate synthase and glutamate synthase, respectively) as a potent antitumor antibiotic that induces apoptosis in human lymphoblastoid cells. Acivicin is an inhibitor of GGT used for solid tumor research. Uses: Protease inhibitor. Synonyms: (S-(R*,R*))-4,5-Dihydro-alpha-amino-3-chloro-5-isoxazoleacetic acid; (alpha-S,5S)-alpha-Amino-3-chloro-4,5-dihydro-5-isoxazoleacetic acid; (alphaS,5S)-alpha-Amino-3-chlor-4,5-dihydro-5-isoxazolylessigsaeure. Grade: ≥98% by HPLC. CAS No. 42228-92-2. Molecular formula: C5H7ClN2O3. Mole weight: 178.57. | |
| Aclarubicin A | Aclarubicin is an oligosaccharide anthracycline antineoplastic antibiotic isolated from the bacterium Streptomyces galilaeus. It intercalates into DNA and interacts with topoisomerases I and II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. It is antagonistic to other agents that inhibit topoisomerase II, such as etoposide, teniposide and amsacrine. It has potent antineoplastic activity. It is used in the treatment of cancer. It can induce histone eviction from chromatin upon intercalation. It has been listed. Uses: Aclarubicin has potent antineoplastic activity. it is used in the treatment of cancer. it can induce histone eviction from chromatin upon intercalation. Synonyms: 11-Dioxo-4-((2,3,6-trideoxy-4-o-(2,6-dideoxy-4-o-((2r-trans)-tetrahydro-6-met; 1-naphthacenecarboxylicacid,2-ethyl-1,2,3,4,6,11-hexahydro-2,5,7-trihydroxy-6; (1R,2R,4S)-methyl 4-(((2R,5S,6S)-4-(dimethylamino)-5-(((2S,4S,5S,6S)-4-hydroxy-6-methyl-5-(((2R,6S). Grade: ≥95%. CAS No. 57576-44-0. Molecular formula: C42H53NO15. Mole weight: 811.88. | |
| Aclarubicin hydrochloride | Aclarubicin is an oligosaccharide anthracycline antineoplastic antibiotic isolated from the bacterium Streptomyces galilaeus. Aclarubicin intercalates into DNA and interacts with topoisomerases I and II, thereby inhibiting replication and repair of DNA and RNA, and protein synthesis. Aclarubicin is antagonistic to other agents that inhibit topoisomerase II, such as etoposide, teniposide and amsacrine. This agent is less cardiotoxic than doxorubicin and daunorubicin. Uses: Antibiotics, antineoplastic. Synonyms: Aclacinon; Aclaplastin; Aclacinomycin A Hydrochloride; Aclarubicin HCl; Aclarubicina Clorhidrato [Spanish]. Grade: >98%. CAS No. 75443-99-1. Molecular formula: C42H54ClNO15. Mole weight: 848.33. | |
| Ac-Lys-AMC | Ac-Lys-AMC, also known as MAL, is a fluorescent substrate for histone deacetylases (HDACs). Synonyms: (S)-2-Acetamido-6-amino-N-(4-methyl-2-oxo-2H-chromen-7-yl)hexanamide; N2-Acetyl-N-(4-methyl-2-oxo-2H-chromen-7-yl)-L-lysinamide; Hexanamide, 2-(acetylamino)-6-amino-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-, (2S)-. Grade: ≥98%. CAS No. 156661-42-6. Molecular formula: C18H23N3O4. Mole weight: 345.40. | |
| Ac-Octreotide | Ac-Octreotide is an impurity of Octreotide, which is a synthetic long-acting cyclic octapeptide used as a more potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Synonyms: Ac-DPhe-Cys-Phe-DTrp-Lys-Thr-Cys-Thr-ol(Cys2&Cys7 bridge); N2.1-Acetyloctreotide; Ac-D-Phe-c(Cys-Phe-D-Trp-Lys-Thr-Cys)-Thr-ol; Octreotide EP Impurity I; Ac-D-Phenylalanyl-L-cystyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-L-cystyl-L-threoninol (Disulfide Bridge between Cys2-Cys7); N-Acetyl-Phe-Octreotide; L-Cysteinamide, N-acetyl-D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2→7)-disulfide; L-Cysteinamide, N-acetyl-D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2→7)-disulfide, [R-(R*,R*)]-; N-Acetyl-D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-L-cysteinamide cyclic (2→7)-disulfide; D-Phe(Ac)-Octreotide; Ac-D-Phe-Cys-Phe-D-Trp-Lys-Thr-Cys-Thr-ol (Disulfide bridge: Cys2-Cys7); Acetyl-Octreotide; Acetyl-Phe1-octreotide; N-Acetyl-D-phenylalanyl-L-hemicystyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-L-hemicystyl-L-threoninol cyclic (2→7)-disulfide. Grade: ≥95%. CAS No. 83795-61-3. Molecular formula: C51H68N10O11S2. Mole weight: 1061.28. | |
| Acotiamide impurity 1 | An analogue of ACOTIAMIDE. Synonyms: 2-amino-4,5-dihydrothiazole-4-carboxylic acid. Grade: ≥ 98% (HPLC). CAS No. 2150-55-2. Molecular formula: C21H30N4O5S. Mole weight: 450.56. | |
| ACRIFLAVIN-BIOTIN CONJUGATE | ACRIFLAVIN-BIOTIN CONJUGATE. Synonyms: 2,7-BIS(AMINO)-9-(BIOTINYLAMIDOETHYLAMINO)ACRIDINE; ACRIFLAVIN-BIOTIN CONJUGATE. Grade: 95%. CAS No. 1041387-90-9. Molecular formula: C25H31N7O2S. Mole weight: 493.62. | |
| Acriflavine hydrochloride | Acriflavine Hydrochloride is an inhibitor of HIF-1α. Acriflavine is a topical antiseptic agent and has also been used for the treatment of external fungal infections. Synonyms: Acyclovir hydrochloride; 3,6-diamino-10-methacrylonitrile hydrogen chloride. Grade: >95%. CAS No. 8063-24-9. Molecular formula: C27H28Cl4N6. Mole weight: 578.36. | |
| Ac-RYYRIK-NH2 | Ac-RYYRIK-NH may provide a promising starting point for in vivo tests for antagonism of the action of noc/OFQ and for the further development of highly active and specific antagonists. Synonyms: L-Lysinamide, N2-acetyl-L-arginyl-L-tyrosyl-L-tyrosyl-L-arginyl-L-isoleucyl-; N2-Acetyl-L-arginyl-L-tyrosyl-L-tyrosyl-L-arginyl-L-isoleucyl-L-lysinamide; Ac-Arg-Tyr-Tyr-Arg-Ile-Lys-NH2; N-acetyl-L-arginyl-L-tyrosyl-L-tyrosyl-L-arginyl-L-isoleucyl-L-lysinamide. Grade: ≥95%. CAS No. 200959-48-4. Molecular formula: C44H70N14O9. Mole weight: 939.12. | |
| Ac-RYYRIK-NH2 acetate | Ac-RYYRIK-NH2 acetate is a potent and partial agonist on ORL1 transfected in CHO cells (Kd = 1.5 nM). Ac-RYYRIK-NH2 is a specific antagonist for the activation of G protein and competitively antagonizes the stimulation of [35S]-GTPgS binding to G proteins by nociceptin/orphanin FQ (noc/OFQ) in membranes and sections of rat brain. Synonyms: Ac-Arg-Tyr-Tyr-Arg-Ile-Lys-NH2.CH3CO2H; N-acetyl-L-arginyl-L-tyrosyl-L-tyrosyl-L-arginyl-L-isoleucyl-L-lysinamide acetic acid. Grade: ≥95%. CAS No. 2863659-08-7. Molecular formula: C46H74N14O11. Mole weight: 999.17. | |
| Ac-RYYRWK-NH2 | Ac-RYYRWK-NH, a hexapeptide, is a partial agonist of the nociceptin/orphanin FQ (N/OFQ) peptide (NOP) receptorr (Ki = 0.71 nM), which exhibits selectivity over μ, δ and κ opioid receptors (IC50 > 4000 nM). Synonyms: L-Lysinamide, N2-acetyl-L-arginyl-L-tyrosyl-L-tyrosyl-L-arginyl-L-tryptophyl-; N2-Acetyl-L-arginyl-L-tyrosyl-L-tyrosyl-L-arginyl-L-tryptophyl-L-lysinamide; Ac-Arg-Tyr-Tyr-Arg-Trp-Lys-NH2; N-acetyl-L-arginyl-L-tyrosyl-L-tyrosyl-L-arginyl-L-tryptophyl-L-lysinamide. Grade: ≥95%. CAS No. 200959-47-3. Molecular formula: C49H69N15O9. Mole weight: 1012.17. | |
| Ac-RYYRWK-NH2 acetate | Ac-RYYRWK-NH2 acetate is a potent and selective partial agonist of the nociceptin receptor (NOP), which is the endogenous ORL1 receptor agonist. Synonyms: Ac-Arg-Tyr-Tyr-Arg-Trp-Lys-NH2.CH3CO2H; N-acetyl-L-arginyl-L-tyrosyl-L-tyrosyl-L-arginyl-L-tryptophyl-L-lysinamide acetic acid. Grade: ≥95%. CAS No. 2863657-54-7. Molecular formula: C51H73N15O11. Mole weight: 1072.22. | |
| Ac-RYYRWK-NH2 TFA | Ac-RYYRWK-NH2 is a potent and selective partial agonist for the nociceptin receptor (NOP). Synonyms: Ac-Arg-Tyr-Tyr-Arg-Trp-Lys-NH2.TFA; N-acetyl-L-arginyl-L-tyrosyl-L-tyrosyl-L-arginyl-L-tryptophyl-L-lysinamide trifluoroacetic acid; L-Lysinamide, N2-acetyl-L-arginyl-L-tyrosyl-L-tyrosyl-L-arginyl-L-tryptophyl-, mono(trifluoroacetate) (salt). Grade: ≥95%. CAS No. 408305-09-9. Molecular formula: C51H70F3N15O11. Mole weight: 1126.19. | |
| Actagardin | It is a peptide antibiotic produced by several species of actinoplanes. It has the activity against Gram-positive and Gram-negative bacteria. It inhibits the biosynthesis of peptidoglycan. Synonyms: Actagardine; Antibiotic A 3802-IV-3; Gardimycin; D-Cysteinyl-L-serylglycyl-L-tryptophyl-L-valyl-L-cysteinyl-(2S,3S)-2-amino-3-mercaptobutanoyl-L-leucyl-(2S,3S)-2-amino-3-mercaptobutanoyl-L-isoleucyl-L-α-glutamyl-L-cysteinylglycyl-(2S,3S)-2-amino-3-mercaptobutanoyl-L-valyl-L-isoleucyl-L-cysteinyl-L-alanyl-L-cysteine S14-Oxide; H-D-Ala-Leu-D-Abu-Ile-D-Glu-D-Abu-D-Ala-Val-D-Trp-Gly-D-Ser-D-Ala-Gly-D-Abu-Val-Ile-D-Ala-Ala-D-Ala-OH. Grade: >98% by HPLC. CAS No. 59165-34-3. Molecular formula: C81H132N20O23. Mole weight: 1754.03. | |
| ACTH (1-10), human | Adrenocorticotropic hormone (ACTH) (1-10) is an N-terminal peptide fragment of ACTH, a peptide hormone produced by the anterior pituitary gland that is involved in the biological stress response. Synonyms: H-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-OH; L-seryl-L-tyrosyl-L-seryl-L-methionyl-L-alpha-glutamyl-L-histidyl-L-phenylalanyl-L-arginyl-L-tryptophyl-glycine; ACTH (1-10) (human, mouse, rat, porcine, bovine, ovine); Adrenocorticotropic Hormone (1-10); Corticotropin (1-10); Adrenocorticotropic Hormone (ACTH) (1-10), human. Grade: ≥97% by HPLC. CAS No. 2791-5-1. Molecular formula: C59H78N16O16S. Mole weight: 1299.41. | |
| ACTH 11-24 | ACTH(11-24) is a fragment of the adrenocorticotropic hormone (ACTH) and an antagonist of the adrenocorticotropic hormone (ACTH) receptor that induces cortisol release. Synonyms: Adrenocorticotropic Hormone (11-24); H-Lys-Pro-Val-Gly-Lys-Lys-Arg-Arg-Pro-Val-Lys-Val-Tyr-Pro-OH; L-lysyl-L-prolyl-L-valyl-glycyl-L-lysyl-L-lysyl-L-arginyl-L-arginyl-L-prolyl-L-valyl-L-lysyl-L-valyl-L-tyrosyl-L-proline; a11-24-Corticotropin; alpha11-24-Corticotropin; Adrenocorticotropic hormone fragment 11-24, human. Grade: ≥90%. CAS No. 4237-93-8. Molecular formula: C77H134N24O16. Mole weight: 1652.04. | |
| ACTH 1-13 | ACTH (1-13) is a 13-aa peptide with cytoprotective effects in the model of ethanol induced gastric lesions in rats. Uses: Hormones. Synonyms: Adrenocorticotropic Hormone (1-13); H-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-OH; L-seryl-L-tyrosyl-L-seryl-L-methionyl-L-alpha-glutamyl-L-histidyl-L-phenylalanyl-L-arginyl-L-tryptophyl-glycyl-L-lysyl-L-prolyl-L-valine; Tridecactide; Des-acetyl MSH; DE-alpha-Msh; (Des-acetyl)-alpha-MSH; alpha 1-13-Corticotropin, human; Desacetyl alpha-melanocyte-stimulating hormone; a1-13-Corticotropin. Grade: ≥95%. CAS No. 22006-64-0. Molecular formula: C75H106N20O19S. Mole weight: 1623.83. | |
| ACTH 1-17 | ACTH (1-17) is a peptide fragment of ACTH, a tropic hormone produced by the anterior pituitary. Synonyms: Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-Gly-Lys-Lys-Arg; Alpha1-17-ACTH; a1-17-Corticotropin; L-seryl-L-tyrosyl-L-seryl-L-methionyl-L-alpha-glutamyl-L-histidyl-L-phenylalanyl-L-arginyl-L-tryptophyl-glycyl-L-lysyl-L-prolyl-L-valyl-glycyl-L-lysyl-L-lysyl-L-arginine; 1-Ala-17-Lys-ACTH 4-amino-n-butylamide; 1-beta-Alanine-17-(L-2,6-diamino-N-(4-aminobutyl)hexanamide)-alpha1-17-corticotrophin; alsactide; Synchrodyn; Adrenocorticotropic Hormone Fragment 1-17 human, rat. Grade: 98%. CAS No. 7266-47-9. Molecular formula: C95H145N29O23S. Mole weight: 2093.41. | |
| ACTH (1-39), Porcine | ACTH (1-39) is a potent agonist of melanocortin receptor 2 (MC2R) with an EC50 value of 57 pM in HeLa cells expressing the mouse receptor. Synonyms: Adrenocorticotropic Hormone from porcine pituitary; Adrenocorticotropic Hormone Fragment 1-39; Corticotropin A. Grade: 95%. CAS No. 9061-27-2. Molecular formula: C210H314N56O57S. Mole weight: 4567.15. | |
| ACTH (1-39), rat | ACTH (1-39) is a potent agonist of melanocortin receptor 2 (MC2R) with an EC50 value of 57 pM in HeLa cells expressing the mouse receptor. Synonyms: ACTH 1-39; ACTH (1-39) (MOUSE, RAT); ACTH (1-39) (RAT). Grade: 98%. CAS No. 77465-10-2. Molecular formula: C210H315N57O57S1. Mole weight: 4582.16. | |
| ACTH (18-39) (human) | ACTH (18-39) (human) is a C-terminal peptide fragment of ACTH, a tropic hormone produced by the anterior pituitary. Synonyms: Adrenocorticotropic Hormone (ACTH) (18-39), human; H-Arg-Pro-Val-Lys-Val-Tyr-Pro-Asn-Gly-Ala-Glu-Asp-Glu-Ser-Ala-Glu-Ala-Phe-Pro-Leu-Glu-Phe-OH; L-arginyl-L-prolyl-L-valyl-L-lysyl-L-valyl-L-tyrosyl-L-prolyl-L-asparagyl-glycyl-L-alanyl-L-alpha-glutamyl-L-alpha-aspartyl-L-alpha-glutamyl-L-seryl-L-alanyl-L-alpha-glutamyl-L-alanyl-L-phenylalanyl-L-prolyl-L-leucyl-L-alpha-glutamyl-L-phenylalanine; Adrenocorticotropic Hormone Fragment 18-39 human; CLIP. Grade: ≥95%. CAS No. 53917-42-3. Molecular formula: C112H165N27O36. Mole weight: 2465.67. | |
| ACTH 22-39 | ACTH (22-39) is a peptide fragment of ACTH, a tropic hormone produced by the anterior pituitary. Synonyms: Adrenocorticoptropic Hormone Fragment 22-39; ACTH (22-39) (human); H-Val-Tyr-Pro-Asn-Gly-Ala-Glu-Asp-Glu-Ser-Ala-Glu-Ala-Phe-Pro-Leu-Glu-Phe-OH; L-valyl-L-tyrosyl-L-prolyl-L-asparagyl-glycyl-L-alanyl-L-alpha-glutamyl-L-alpha-aspartyl-L-alpha-glutamyl-L-seryl-L-alanyl-L-alpha-glutamyl-L-alanyl-L-phenylalanyl-L-prolyl-L-leucyl-L-alpha-glutamyl-L-phenylalanine; beta-Cell-Tropin. Grade: ≥95% by HPLC. CAS No. 37548-29-1. Molecular formula: C90H125N19O32. Mole weight: 1985.06. | |
| ACTH (4-10) | ACTH (4-10) is a fragment of Adrenocorticotropic Hormone (ACTH), a melanocortin 4 (MC4R) receptor agonist. Synonyms: α-MSH (4-10); ACTH (4-10), human; corticotropin (4-10); H-Met-Glu-His-Phe-Arg-Trp-Gly-OH; Met-glu-his-phe-arg-trp-gly. Grade: >95%. CAS No. 4037-1-8. Molecular formula: C44H59N13O10S. Mole weight: 962.08. | |
| ACTH 4-11 | ACTH (4-11) is a peptide fragment of adrenocorticotropic hormone, a peptide hormone found in the brain that is involved in the biological stress response. Synonyms: Adrenocorticotropic Hormone (4-11), human; H-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-OH; L-methionyl-L-alpha-glutamyl-L-histidyl-L-phenylalanyl-L-arginyl-L-tryptophyl-glycyl-L-lysine; ACTH (4-11) (human, mouse, rat, porcine, bovine, ovine); MEHFRWGK-OH; N2-(N-(N-(N2-(N-(N-(N-L-Methionyl-L-alpha-glutamyl)-L-histidyl)-L-phenylalanyl)-L-arginyl)-L-tryptophyl)glycyl)-L-lysine. Grade: ≥98%. CAS No. 67224-41-3. Molecular formula: C50H71N15O11S. Mole weight: 1090.26. | |
| Ac-Thr-Ile-Nle-psi(CH2NH)Nle-Gln-Arg-NH2 | Ac-Thr-Ile-Nle-psi(CH2NH)Nle-Gln-Arg-NH2 is an HIV-1 protease inhibitor whose sequence is derived from the cleavage site of the viral gag-pol poly-protein. Electron density studies have shown that this inhibitor binds to the active site of the HIV-1 protease. Synonyms: MVT-101; N-acetyl-Thr-Ile-Nle-psi(CH2-NH)-Nle-Gln-Arg-amide; N-acetyl-threonyl-isoleucyl-norleucyl-psi(CH2-NH)-norleucyl-glutaminyl-argininamide; N-{(2S)-2-[(N-Acetyl-L-threonyl-L-isoleucyl)amino]hexyl}-L-norleucyl-L-glutaminyl-L-argininamide; L-Argininamide, N-[(2S)-2-[[(2S,3S)-2-[[(2S,3R)-2-(acetylamino)-3-hydroxy-1-oxobutyl]amino]-3-methyl-1-oxopentyl]amino]hexyl]-L-norleucyl-L-glutaminyl-. Grade: 95%. CAS No. 128657-47-6. Molecular formula: C35H67N11O8. Mole weight: 769.98. | |
| Actinobolin | Actinobolin is a broad-spectrum antibiotic isolated from Str. griseoviridus var. atrofaczens. Actinobolin has antibacterial activity, but it can be offset by a variety of amino acids or pyruvate. It has inhibitory effect on Ehrlich ascites tumor, sarcoma 180, etc. Synonyms: 4-(2-Aminopropionamido)-3,4,4a,5,6,7-hexahydro-5,6,8-trihydroxy-3-methylisocoumarin. CAS No. 24397-89-5. Molecular formula: C13H20N2O6. Mole weight: 300.31. | |
| Actinomycin D | Actinomycin D is a chromopeptide antineoplastic antibiotic that exhibits high antibacterial and antitumor activity. Actinomycin D binds to single- and double-stranded DNA and subsequent inhibition of RNA and protein synthesis. Synonyms: Actinomycin; Cosmegen; Cosmegen Lyovac; Dactinomycin; Lyovac Cosmegen. CAS No. 50-76-0. Molecular formula: C62H86N12O16. Mole weight: 1255.41. | |
| Actinonin | Actinonin, a natural antibacterial agent produced by Actinomyces, is a potent reversible peptide deformylase (PDF) inhibitor with Ki of 0.28 nM. Actinonin inhibits aminopeptidase M, aminopeptidase N and leucine aminopeptidase. Actinonin also inhibits MMP-1, MMP-3, MMP-8, MMP-9, and hmeprin α with Ki of 300 nM, 1,700 nM, 190 nM, 330 nM, and 20 nM, respectively. Actinonin induces apoptosis and has antiproliferative and antitumor activities. Uses: Anti-bacterial agents. Synonyms: 3-[[1-[(2-(Hydroxymethyl)-1-pyrrolidinyl)carbonyl]-2-methylpropyl]carbamoyl]octanohydroxamic acid. Grade: ≥98% by TLC. CAS No. 13434-13-4. Molecular formula: C19H35N3O5. Mole weight: 385.51. | |
| Actinopyrone A | Actinopyrone A is an antibiotic isolated from Streptomyces pacttm. Actinopyrone has a relaxing effect on the coronary blood vessels of anesthetized dogs, and has weak anti-gram-positive bacteria and trichoderma activity. Synonyms: 4H-Pyran-4-one, 2-(10-hydroxy-3,7,9,11-tetramethyl-2,5,7,11-tridecatetraenyl)-6-methoxy-3,5-dimethyl-. Grade: >95%. CAS No. 88378-59-0. Molecular formula: C25H36O4. Mole weight: 400.55. | |
| Actinopyrone B | Actinopyrone B is an antibiotic isolated from Streptomyces pacttm. Actinopyrone has a relaxing effect on the coronary blood vessels of anesthetized dogs, and has weak anti-gram-positive bacteria and trichoderma activity. Synonyms: 4H-Pyran-4-one, 2-(10-hydroxy-3,7,9,11-tetramethyl-2,5,7,11-tridecatetraenyl)-6-methoxy-3-methyl-. Grade: 95%. CAS No. 88378-60-3. Molecular formula: C24H34O4. Mole weight: 386.52. | |
| Actinopyrone C | Actinopyrone C is an antibiotic isolated from Streptomyces pacttm. Actinopyrone has a relaxing effect on the coronary blood vessels of anesthetized dogs, and has weak anti-gram-positive bacteria and trichoderma activity. Synonyms: 4H-Pyran-4-one, 3-ethyl-6-(10-hydroxy-3,7,9,11-tetramethyl-2,5,7,11-tridecatetraenyl)-2-methoxy-5-methyl-. Grade: 95%. CAS No. 88378-61-4. Molecular formula: C26H38O4. Mole weight: 414.58. | |
| Actinotetraose Hexatiglate | A unique tetrasaccharide with six tiglate esters isolated from an unidentified amycolatopsis culture. It is a potent antitumour agent. Synonyms: Tigloside; 2-[(2E)-2-Methyl-2-butenoate]-O-3,4-bis-O-[(2E)-2-methyl-1-oxo-2-buten-1-yl]-β-D-glucopyranosyl-(1→2)-6-O-[(2E)-2-methyl-1-oxo-2-buten-1-yl]-α-D-glucopyranosyl O-3,4-bis-O-[(2E)-2-methyl-1-oxo-2-buten-1-yl]-β-D-glucopyranosyl-(1→2)-α-D-Glucopyranoside; 2-O-[3,4-bis-O-[(2E)-2-methyl-1-oxo-2-butenyl]-β-D-glucopyranosyl]-6-O-[(2E)-2-methyl-1-oxo-2-butenyl]-α-D-glucopyranosyl 2-O-[3,4-bis-O-[(2E)-2-Methyl-1-oxo-2-butenyl]-β-D-glucopyranosyl]-α-D-Glucopyranoside 6-[(2E)-2-Methyl-2-butenoate]. Grade: >95% by HPLC. CAS No. 216590-44-2. Molecular formula: C54H78O27. Mole weight: 1159.18. | |
| Activated Protein C (390-404), human | Activated Protein C (390-404) human, a peptide of the activated protein C (a vitamin K-dependent serine protease), effectively inhibits the anticoagulant activity of APC. Synonyms: H-Tyr-Gly-Val-Tyr-Thr-Lys-Val-Ser-Arg-Tyr-Leu-Asp-Trp-Ile-His-OH; L-tyrosyl-glycyl-L-valyl-L-tyrosyl-L-threonyl-L-lysyl-L-valyl-L-seryl-L-arginyl-L-tyrosyl-L-leucyl-L-alpha-aspartyl-L-tryptophyl-L-isoleucyl-L-histidine; APC (390-404) Human. Grade: ≥95%. CAS No. 146340-20-7. Molecular formula: C91H130N22O23. Mole weight: 1900.14. | |
| AC-TYR-VAL-LYS(BIOTINYL)-ASP-2,6-DIMETHYLBENZOYLOXYMETHYLKETONE | AC-TYR-VAL-LYS(BIOTINYL)-ASP-2,6-DIMETHYLBENZOYLOXYMETHYLKETONE. Synonyms: AC-TYR-VAL-LYS(BIOTIN)-ASP-2,6-DIMETHYLBENZOYLOXYMETHYLKETONE; AC-TYR-VAL-LYS(BIOTIN)-ASP-CH2OCO-(2,6-DIMETHYL)C6H3; AC-TYR-VAL-LYS(BIOTINYL)-ASP-2,6-DIMETHYLBENZOYLOXYMETHYLKETONE; AC-YVK(BIOTIN)-D-AOM; AC-YVK(BIOTIN)DCH2OCO-(2,6-DIMETHYL)C6H3; AC-YVK(BIOTIN. Grade: 95%. CAS No. 154719-25-2. Molecular formula: C46H63N7O12S. Mole weight: 938.1. | |
| ACV 1 | ACV 1 has been found to be a neuronal nicotinic receptor antagonist and could probably alleviate neuropathic pain. Synonyms: Conotoxin Vc1.1. Grade: ≥98% by HPLC. CAS No. 740980-24-9. Molecular formula: C71H103N23O25S4. Mole weight: 1806.98. | |
| Ac-Val-Asp-Val-Ala-Asp-aldehyde (pseudo acid) | Ac-VDVAD-CHO is an inhibitor of caspase-2, -3, and -7 (Kis = 3.5, 1, and 7.5 nM, respectively). Synonyms: Ac-VDVAD-CHO; N-acetyl-L-valyl-L-alpha-aspartyl-L-valyl-L-alanyl-L-aspart-1-al; N-Acetyl-L-valyl-L-α-aspartyl-L-valyl-N-[(2S)-1-carboxy-3-oxo-2-propanyl]-L-alaninamide; L-Alaninamide, N-acetyl-L-valyl-L-α-aspartyl-L-valyl-N-[(1S)-2-carboxy-1-formylethyl]-; Caspase-2 Inhibitor (Aldehyde). Grade: ≥95%. CAS No. 194022-51-0. Molecular formula: C23H37N5O10. Mole weight: 543.57. | |
| Ac-Val-Glu-Ile-Asp-aldehyde (pseudo acid) | Ac-VEID-CHO is an inhibitor of caspase-6 (IC50 = 16.2 nM). It is selective for caspase-6 over caspase-7 (IC50 = 162.1 nM) but can also inhibit caspase-3 (IC50 = 13.6 nM). Synonyms: N-acetyl-L-valyl-L-alpha-glutamyl-L-isoleucyl-L-aspart-1-al; N-acetyl-Val-Glu-Ile-Asp-aldehyde; N-Acetyl-L-valyl-L-alpha-glutamyl-N-[(2S)-1-carboxy-3-oxo-2-propanyl]-L-isoleucinamide; L-Isoleucinamide, N-acetyl-L-valyl-L-α-glutamyl-N-[(1S)-2-carboxy-1-formylethyl]-; N-Acetyl-Val-Glu-Ile-Asp-al; (4S,7S,10S,13S)-10-((S)-sec-butyl)-7-(2-carboxyethyl)-13-formyl-4-isopropyl-2,5,8,11-tetraoxo-3,6,9,12-tetraazapentadecan-15-oic acid; Caspase-6 Inhibitor; Ac-VEID-CHO. Grade: ≥95%. CAS No. 319494-39-8. Molecular formula: C22H36N4O9. Mole weight: 500.54. | |
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