BOC Sciences - Products
BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
Product | Description | |
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Agmatine sulfate salt Quick inquiry Where to buy | Agmatine sulfate, the sulfate preparation of Agmatine, is an endogenous agonist at imidazoline receptor and a NO synthase inhibitor. Agmatine displaces clonidine at α2-adrenergic and at imidazoline receptors and produces blockade of the NMDA-receptor associated cation channels. Nutritional supplement in health care products. Uses: Ingredient of health care products. Synonyms: 2-(4-aminobutyl)guanidine;sulfuric acid. Grades: ≥ 93 % (HPLC). CAS No. 2482-00-0. Molecular formula: C5H16N4O4S. Mole weight: 228.27. | |
AGN 192403 hydrochloride Quick inquiry Where to buy | The hydrochloride salt form of AGN 192403, which has been found to show high affinity to imidazoline I1 receptor. Synonyms: AGN-192403 hydrochloride, AGN192403 hydrochloride, AGN 192403 hydrochloride, AGN-192403 HCl; (±)-2-endo-Amino-3-exo-isopropylbicyclo[2.2.1]heptane hydrochloride. Grades: ≥95% by HPLC. CAS No. 1021868-90-5. Molecular formula: C10H19N.HCl. Mole weight: 189.73. | |
AGN 193109 Sodium Salt Quick inquiry Where to buy | AGN 193109 is a potent antagonist of retinoic acid receptors (RARs, Kd = 2, 2, and 3 nM for RARα, β, and γ, respectively). Synonyms: 4-[2-[5,6-dihydro-5,5-dimethyl-8-(4-methylphenyl)-2-naphthalenyl]ethynyl]-benzoic acid monosodium salt; CD 3106 Sodium Salt; Benzoic acid, 4-[2-[5,6-dihydro-5,5-dimethyl-8-(4-methylphenyl)-2-naphthalenyl]ethynyl]-, sodium salt (1:1); sodium 4-((5,5-dimethyl-8-(p-tolyl)-5,6-dihydronaphthalen-2-yl)ethynyl)benzoate. Grades: 95%. Molecular formula: C28H23NaO2. Mole weight: 414.47. | |
Agomelatine Quick inquiry Where to buy | Agomelatine is a melatoninergic agonist and selective antagonist of 5-HT2C receptors, and has been shown to be active in several animal models of depression. Agomelatine (S20098) displayed pKi values of 6.4 and 6.2 at native (porcine) and cloned, human (h)5-hydroxytryptamine (5-HT)2C receptors, respectively. Synonyms: AGO 178; AGO-178; AGO178; N-(2-(7-methoxy-1-naphthyl)ethyl)acetamide; S 20098; S-20098; S20098. trade names: Valdoxan, Melitor, Thymanax. Grades: 0.99. CAS No. 138112-76-2. Molecular formula: C15H17NO2. Mole weight: 243.31. | |
Agomelatine-[d3] Quick inquiry Where to buy | Agomelatine-[d3] is the labelled analogue of Agomelatin, which is a melatoninergic agonist and selective 5-HT2C receptor antagonist. It is used as an atypical antidepressant in the treatment of major depressive disorder. Synonyms: Agomelatine-D3 (acetamide-2,2,2-D3); Valdoxan-d3; Thymanax-d3; N-(2-(7-Methoxynaphthalen-1-yl)ethyl)acetamide-d3; Melitor-d3. Grades: 95% by HPLC; 98% atom D. CAS No. 1079389-38-0. Molecular formula: C15H14D3NO2. Mole weight: 246.32. | |
Agomelatine hydrochloride Quick inquiry Where to buy | The hydrochloride salt form of Agomelatine that is an antidepressant agent for acting as an antagonism of the 5-HT2C receptor. It is also an antagonist of 5-HT2B receptors. IC50: 6.2 and 6.6 for 5-HT2c and 5-HT2b respectively (pKi ). Uses: The hydrochloride salt form of agomelatine that is an antidepressant agent for acting as an antagonism of the 5-ht2c receptor. Synonyms: Valdoxan hydrochloride; S-20098 hydrochloride; S 20098 hydrochloride; S20098 hydrochloride. Grades: 98%. CAS No. 1176316-99-6. Molecular formula: C15H18ClNO2. Mole weight: 279.76. | |
Agomelatine Impurity 1 Quick inquiry Where to buy | An analogue of Agomelatine. Synonyms: N-[2-(7-methoxy-3,4-dihydro-naphthalen-1-yl)ethyl]. Grades: > 95%. CAS No. 1352139-51-5. Molecular formula: C15H19NO2. Mole weight: 245.32. | |
Agomelatine Impurity 2 Quick inquiry Where to buy | An analogue of Agomelatine. Synonyms: (E)-1-[2-(acetylamino)ethylidene]; (E)-N-(2-(7-methoxy-3,4-dihydronaphthalen-1(2H)-ylidene. Grades: > 95%. CAS No. 178677-39-9. Molecular formula: C15H19NO2. Mole weight: 245.32. | |
Agomelatine Impurity A Quick inquiry Where to buy | Agomelatine Impurity A is an impurity originating from the renowned Agomelatine, a notable depression-alleviating medication. CAS No. 32820-10-3. Molecular formula: C11H14O2. | |
Agomelatine Impurity B Quick inquiry Where to buy | An analogue of Agomelatine. Synonyms: 2-(7-Methoxynaphthalen-1-yl)acetamide. Grades: > 95%. CAS No. 138113-07-2. Molecular formula: C13H13NO2. Mole weight: 215.25. | |
Agomelatine Impurity D Quick inquiry Where to buy | An analogue of Agomelatine. Synonyms: N-Acetyl-N-[2-(7-methoxy-1-naphthalenyl)ethyl]acetamide. Grades: > 95%. CAS No. 1379005-34-1. Molecular formula: C17H19NO3. Mole weight: 285.35. | |
Agomelatine Impurity I Quick inquiry Where to buy | An analogue of Agomelatine. Synonyms: Agomelatine Dimer Acetamide. Grades: > 95%. CAS No. 1385018-58-5. Molecular formula: C28H29NO3. Mole weight: 427.55. | |
Agomelatine Impurity II Quick inquiry Where to buy | An analogue of Agomelatine. Synonyms: Agomelatine Dimer Urea. Grades: > 95%. CAS No. 185421-27-6. Molecular formula: C27H28N2O3. Mole weight: 428.54. | |
Agonodepside B Quick inquiry Where to buy | Agonodepside B is a fungal metabolite produced by the strain of the endophytic fungus F7524. Synonyms: benzoic acid, 4-[[2,4-dihydroxy-3-methyl-6-[(1E)-1-methyl-1-propenyl]benzoyl]oxy]-2-hydroxy-3-methyl-6-[(1E)-1-methyl-1-propenyl]-. Grades: >95%. CAS No. 445298-41-9. Molecular formula: C24H26O7. Mole weight: 426.46. | |
Agouti-related Protein (AGRP) (25-82), human Quick inquiry Where to buy | Agouti-related protein (AgRP) is a neuropeptide produced in the brain by the AgRP/NPY neuron. It acts as a melanocortin receptor antagonist that exerts a central inhibitory action on the Hypothalamic-Pituitary-Thyroid (HPT) Axis. Grades: 95%. Molecular formula: C279H468N80O90S1. Mole weight: 6415.39. | |
AGPTNA Chain A, Pcbp2 Kh1-Kh2 Domains (38-58) Quick inquiry Where to buy | ||
Agrochelin Quick inquiry Where to buy | It is produced by the strain of Agrobacterium sp. ALET-304. The IC50 of soil bactericin against P-388 was 0.053 ?ol/L, and the IC50 of cell a1-549, HT-29 and MEL 38 was between 0.107-0.268 ?ol/L. Synonyms: (3S)-3-hydroxy-3-{(2S,4R)-2-[(4R)-2-(2-hydroxy-6-pentylphenyl)-4,5-dihydro-1,3-thiazol-4-yl]-3-methyl-1,3-thiazolidin-4-yl}-2,2-dimethylpropanoic acid; CHEBI:65375; Q27133819. Molecular formula: C23H34N2O4S2. Mole weight: 466.66. | |
Agrocin 84 Quick inquiry Where to buy | It is produced by the strain of Agrobacterium radiobacter. It can inhibit DNA synthesis, and sterilize Agrobacterium Tume Faciens. Synonyms: Agrocin; D-Glucofuranose,1-[hydrogen[9-[3-deoxy-5-O-[[(4,5-dideoxy-4-methyl-D-threo-pentonoyl)amino]hydroxyphosphinyl]-b-D-threo-pentofuranosyl]-9H-purin-6-yl]phosphoramidate]; Mono-D-glucofuranosyl[9-[3-deoxy-5-O-[[(4,5-dideoxy-4-methyl-D-threo-pentonoyl)amino]hydroxyphosphinyl]-b-D-threo-pentofuranosyl]-9H-purin-6-yl]phosphoramidate. CAS No. 59111-78-3. Molecular formula: C22H36N6O16P2. Mole weight: 702.50. | |
Agrocybin Quick inquiry Where to buy | It is produced by the strain of Agrocybe dura. It has the activity of anti-gram-positive bacteria, negative bacteria, mycobacterium and mildew, which is unstable and easy to be inactivated. Synonyms: 8-Hydroxy-2,4,6-octatriynamide; A0AFV4JUIT; NSC636326; BRN 1761957; 2,4,6-OCTATRIYNAMIDE, 8-HYDROXY-; SCHEMBL1654320; CHEMBL1967731; CTK8J1637; DTXSID20202786; ZINC5722724; LMFA08010027; AKOS006341004; NSC-63632. Grades: 97%. CAS No. 544-44-5. Molecular formula: C8H5NO2. Mole weight: 147.13. | |
Agrocybin (1-15) Quick inquiry Where to buy | Agrocybin is an antimicrobial peptide produced by Agrocybe cylindracea (Toadstool). It has antibacterial, antifungal and antiviral activity. Synonyms: Ala-Asn-Asp-Pro-Gln-Cys-Leu-Tyr-Gly-Asn-Val-Ala-Ala-Lys-Phe. Grades: ≥96%. Molecular formula: C71H107N19O22S. Mole weight: 1610.80. | |
AH-1763 IIa Quick inquiry Where to buy | AH-1763 la is an antibiotic produced by Streptomyces cyaneus against herpes virus. Its ED50 against herpes simplex virus type 1 (HSV-1) is 2.1 μg/mL, and its IC50 against Vero cells is 15.2 μg/mL. Molecular formula: C22H18O6. Mole weight: 378.37. | |
AH 23848 calcium salt Quick inquiry Where to buy | AH-23848 is a dual antagonist of TP1 and EP4 receptors. Uses: Anti-arrhythmia agents. Synonyms: AH23848; (Z) -7-[ (1R, 2R, 5S) -2-morpholin-4-yl-3-oxo-5-[ (4-phenylphenyl) methoxy]cyclopentyl]hept-4-enoic acid; 81496-19-7; AH 23848; AH-23848; AH-23848B; (-)AH23848; (-)-AH23848; GTPL1949; SCHEMBL3488581; CHEBI:90389; 81443-73-4; (1R,2R,5S)-AH23848; (-)-AH 23848; Q27074357; (4Z)-7-[(1R,2R,5S)-5-[([1,1'-biphenyl]-4-yl)methoxy]-2-(morpholin-4-yl)-3-oxocyclopentyl]hept-4-enoic acid; Rel-(Z)-7-((1R,2R,5S)-5-([1,1'-biphenyl]-4-ylmethoxy)-2-morpholino-3-oxocyclopentyl)hept-4-enoic acid. Grades: ≥90%. CAS No. 81496-19-7. Molecular formula: C29H34NO5·1/2Ca. Mole weight: 993.2. | |
AH 6809 Quick inquiry Where to buy | AH 6809 is an EP1 (pA2 = 6.8) and EP2 (Ki = 350 nM) receptor antagonist. Uses: An ep and dp receptor antagonist with nearly equal affinity for the cloned human ep1, ep2, ep3-iii, and dp1 receptors. Synonyms: AH 6809; AH6809; AH-6809; 6-isopropoxy-9-oxoxanthene-2-carboxylic acid. Grades: ≥95.0%. CAS No. 33458-93-4. Molecular formula: C17H14O5. Mole weight: 298.29. | |
Ah-AMP1 Quick inquiry Where to buy | Ah-AMP1 is an antimicrobial peptide and a plant defensin produced by Aesculus hippocastanum (Horse chestnut). It has antifungal activity. Synonyms: Aesculus hippocastanum antimicrobial protein 1; Leu-Cys-Asn-Glu-Arg-Pro-Ser-Gln-Thr-Trp-Ser-Gly-Asn-Cys-Gly-Asn-Thr-Ala-His-Cys-Asp-Lys-Gln-Cys-Gln-Asp-Trp-Glu-Lys-Ala-Ser-His-Gly-Ala-Cys-His-Lys-Arg-Glu-Asn-His-Trp-Lys-Cys-Phe-Cys-Tyr-Phe-Asn-Cys (Disulfide bridge: Cys2-Cys50, Cys14-Cys35, Cys20-Cys44, Cys24-Cys46). Grades: >98%. CAS No. 169027-67-2. Molecular formula: C245H347N79O75S8. Mole weight: 5855.43. | |
AHK-Cu Quick inquiry Where to buy | AHK-Cu is a naturally-occurring peptide used for skin care and hair growth. | |
AHK Tripeptide-3 Quick inquiry Where to buy | AHK Tripeptide-3 is a 3-amino acid that exhibits activity in hair growth, healing wounds and wound regeneration. Synonyms: Ala-His-Lys; L-alanyl-L-histidyl-L-lysine; alanylhistidyllysine. Grades: 98%. CAS No. 126828-32-8. Molecular formula: C15H26N6O4. Mole weight: 354.41. | |
a-Homonojirimycin Quick inquiry Where to buy | a-Homonojirimycin is a inhibitor of the enzymatic compound called glucosidase used for studying lysosomal storage diseases like Gaucher disease and Pompe disease. Synonyms: α-HNJ; (2R,3R,4R,5S,6R)-2,6-β(dihydroxymethyl)piperidine-3,4,5-triol; α-Homonojirimycin; 3,4,5-Piperidinetriol, 2,6-bis(hydroxymethyl)-, [2R-(2α, 3α, 4β, 5α, 6β)]-; (2R,3R,4R,5S,6R)-2,6-Bis(hydroxymethyl)-3,4,5-piperidinetriol; 2,6-Dideoxy-2,6-imino-D-glycero-L-gulo-heptitol; Homonojirimycin; 3,4,5-Piperidinetriol, 2,6-bis(hydroxymethyl)-, (2α, 3α, 4β, 5α, 6β)-. Grades: ≥98%. CAS No. 119557-99-2. Molecular formula: C7H15NO5. Mole weight: 193.20. | |
AHU-377 hemicalcium salt Quick inquiry Where to buy | LCZ696 is a novel single molecule comprising molecular moieties of valsartan and NEP inhibitor prodrug AHU377 (1:1 ratio). Oral administration of LCZ696 caused dose-dependent increases in atrial natriuretic peptide immunoreactivity (due to NEP inhibition) in Sprague-Dawley rats and provided sustained, dose-dependent blood pressure reductions in hypertensive double-transgenic rats. In healthy participants, a randomized, double-blind, placebo-controlled study (n = 80) of single-dose (200-1200 mg) and multiple-dose (50-900 mg once daily for 14 days) oral administration of LCZ696 showed that peak plasma concentrations were reached rapidly for valsartan (1.6-4.9 hours), AHU377 (0.5-1.1 hours), and its active moiety, LBQ657 (1.8-3.5 hours). LCZ696 is superior to valsartan alone in reducing blood pressure. Preliminary results from a Phase II trial showed that LCZ696 reduced NT-proBNP to a greater extent than valsartan alone, and in addition LCZ696 had beneficial effects on symptoms. Synonyms: calcium 4-(((2S,4R)-1-([1,1'-biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopentan-2-yl)amino)-4-oxobutanoate; AHU337; AHU-337; AHU 337; LCZ696; LCZ 696; LCZ696; Sacubitril. Grades: >98%. CAS No. 1369773-39-6. Molecular formula: C24H28NO5-. Mole weight: 410.48. | |
AI-3 Quick inquiry Where to buy | AI-3 is an antioxidant response element activator and could probably be useful in studies of oxidative stress related diseases. Synonyms: AI-3; AI 3; AI3; 1-Chloro-6,7-dihydro-6,6-dimethyl-3-(methylsulfonyl)-benzo[c]thiophen-4(5H)-one. Grades: ≥98% by HPLC. CAS No. 882288-28-0. Molecular formula: C11H13ClO3S2. Mole weight: 292.80. | |
Aibellin Quick inquiry Where to buy | It is produced by the strain of Vertocimonos poriurn ellipticum D1528. Alberin can enhance ruminant stomach fermentation, increase propionate production and reduce methane production caused by microorganisms in the stomach. Synonyms: AlamethicinI,2-L-alanine-9-L-phenylalanine-12-(2-methylalanine)-19-[N-[1-[[(2-hydroxyethyl)amino]methyl]-2-phenylethyl]-L-a-glutamine]-; L-a-Glutamine,N-acetyl-2-methylalanyl-L-alanyl-2-methylalanyl-L-alanyl-2-methylalanyl-L-alanyl-L-glutaminyl-2-methylalanyl-L-phenylalanyl-2-methylalanylglycyl-2-methylalanyl-2-methylalanyl-L-prolyl-L-valyl-2-methylalanyl-2-methylalanyl-L-a-glutamyl-N-[1-[[(2-hydroxyethyl)amino]methyl]-2-phenylethyl]-,(S)-. CAS No. 151036-29-2. Molecular formula: C94H147N21O27. Mole weight: 2003.29. | |
AICAR 3',5'-Cyclic Phosphate Quick inquiry Where to buy | A cyclic nucleotide with protein kinase and phosphodiesterase activity. Synonyms: 5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranosyl 3':5'-cyclic-monophosphate;5-Amino-1-(3,5-O-phosphinico-β-D-ribofuranosyl)-1H-imidazole-4-carboxamide; NSC 371796. Grades: 94%. CAS No. 35908-14-6. Molecular formula: C9H13N4O7P. Mole weight: 320.2. | |
AICAR-5'-MP / ZMP Quick inquiry Where to buy | AICAR-5'-MP is an analogue of AICA-riboside, an alternative of 5'-AMP. AICAR-5'-MP is a purine precursor with antineoplastic activity and can be used in the study of type 2 diabetes. It can activate AMP-activated protein kinase. Synonyms: 1H-Imidazole-4-carboxamide, 5-amino-1-(5-O-phosphono-β-D-ribofuranosyl)-; 5-Amino-1-(5-O-phosphono-β-D-ribofuranosyl)-1H-imidazole-4-carboxamide; Imidazole-4-carboxamide, 5-amino-1-β-D-ribofuranosyl-, 5'-(dihydrogen phosphate); Imidazole-4-carboxamide, 5-amino-1-β-D-ribofuranosyl-, 5'-phosphate; 5-Amino-1-(5'-phosphofuranoribosyl)-4-imidazolecarboxamide; 5-Amino-1β-D-ribofuranosylimidazole-4-carboxamide 5'-phosphate; 5-Amino-4-imidazolecarboxamide ribonucleoside 5'-monophosphate; 5-Amino-4-imidazolecarboxamide ribonucleotide; 5-Amino-4-imidazolecarboxamide riboside 5'-monophosphate; 5-Amino-4-imidazolecarboxamide ribotide; 5-Aminoimidazole-4-carboxamide ribonucleotide; 5'-Phospho-β-D-ribosyl-5-amino-4-imidazolecarboxamide; 5'-Phosphoribosyl-5-amino-4-imidazolecarboxamide; Acadesine 5'-monophosphate; AICA Ribotide; AICA-Ribonucleotide; AICAR; AICAR monophosphate; AICAR (5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranosyl 5'-monophosphate); Aminoimidazolecarboxamide ribonucleotide; NSC 283955; NSC 292227; ZMP; ZMP (alarmone). Grades: ≥95%. CAS No. 3031-94-5. Molecular formula: C9H15N4O8P. Mole weight: 338.21. | |
AJI-9561 Quick inquiry Where to buy | AJI-9561 is a benzoxazole derivative produced by Streptomyces sp. AJ9561. It has cytotoxic activity with IC50 of 0.88 μmol/L and 1.63 μmol/L for Jorkat and P388 cells, respectively. Its mechanism of action is the same as that of UK-1, which can inhibit DNA topoisomerase U. Synonyms: (2,4'-Bibenzoxazole)-4-carboxylic acid, 2'-(2-hydroxy-6-methylphenyl)-. CAS No. 339300-34-4. Molecular formula: C22H14N2O5. Mole weight: 386.36. | |
Ajmaline Quick inquiry Where to buy | Ajmaline is an alkaloid which could be extracted from Rauwolfia serpentina. It is an antiarrhythmic agent, acting through changing the shreshold and the shape of cardiac action potentials. Synonyms: Cardiorythmine; Ajmalin; Gilurytmal; Raugalline. Grades: >95%. CAS No. 4360-12-7. Molecular formula: C20H26N2O2. Mole weight: 326.43. | |
Ajugasterone C Quick inquiry Where to buy | Ajugasterone C is a steroid found in the herbs of Ajuga ciliata Bunge. Grades: >98%. CAS No. 23044-80-6. Molecular formula: C27H44O7. Mole weight: 480.642. | |
AK-7 Quick inquiry Where to buy | AK-7 is a selective and brain-permeable SIRT2 inhibitor, which displays no effect on SIRT1 or SIRT3. It could decrease neuronal cholesterol levels and improve motor function and ameliorates brain atrophy in a mouse model of Huntington's disease. Synonyms: AK-7; CS-3223; GL-8955; AK7; CS3223; GL8955; AK 7; CS 3223; GL 8955. Grades: >98%. CAS No. 420831-40-9. Molecular formula: C19H21BrN2O3S. Mole weight: 437.35. | |
Akebia saponin D Quick inquiry Where to buy | Asperosaponin VI ususlly comes from the root of Dipsacus asperoides C. Y. Cheng et T. M. Ai. Except for its antioxidant activity, treatment of U937 cells with akebia saponin D (ASD) induced apoptosis in a dose dependent manner. ASD exerted strong cytotoxicity against human and murine leukemia cells. ASD may exert apoptosis-inducing activity via induction of apoptosis through activation chiefly via the nitric oxide and apoptosis-related p53 and Bax gene expression. Uses: Antioxidant. Synonyms: Akebia saponin D; Hederagenin 3-O-alpha-L-arabinopyranosyl-28-beta-D-glucopyranosyl(1?6)-beta-D-glucopyranoside; Asperosaponin ?; Akebia saponin D(Asperosaponin VI); Dipsacaceae saponin. Grades: >98%. CAS No. 39524-08-8. Molecular formula: C47H76O18. Mole weight: 929.1. | |
AKI603 Quick inquiry Where to buy | AKI603 is an inhibitor of Aurora kinase A (AurA) with IC50 of 12.3 nM. It can induce senescence in chronic myeloid leukemia cells carrying the T315I mutation. AKI603 shows strong anti-proliferative activity in leukemia cells. Synonyms: AKI-603. Grades: 98%. CAS No. 1432515-73-5. Molecular formula: C19H23N9O2. Mole weight: 409.4. | |
A-kinase anchor protein 9 (1398-1407) Quick inquiry Where to buy | A-kinase anchor protein 9 (1398-1407) is amino acids 1398 to 1407 fragment of A-kinase anchor protein 9. AKAP-9 is a scaffolding protein that assembles several protein kinases and phosphatases on the centrosome and Golgi apparatus. Synonyms: AKAP-9 (1398-1407). | |
Aklavin Quick inquiry Where to buy | It is produced by the strain of Streptomyces galilaeus. It has the activity of resisting gram positive bacterium, negative bacterium, candida and ringworm. Synonyms: Aclacinomycin T; 1-Deoxypyrromycin; Aclacinomycin; Doxypyrromycin; NSC 100290; CHEBI:74351; 1-Naphthacenecarboxylic acid, 2-ethyl-1,2,3,4,6,11-hexahydro-2,5,7-trihydroxy-6,11-dioxo-4-((2,3,6-trideoxy-3-(dimethylamino)-alpha-L-lyxo-hexapyranosyl)oxy)-, methyl ester, (1R-(1-alpha,2-beta,4-beta))-; aklavine. CAS No. 60504-57-6. Molecular formula: C30H35NO10. Mole weight: 569.60. | |
Aklavinone Quick inquiry Where to buy | Aklavinone is an anthracycline drug with an antitumor effect. CAS No. 16234-96-1. Molecular formula: C22H20O8. Mole weight: 412.39. | |
AKOS B018304 Quick inquiry Where to buy | AKOS B018304 is a potent inhibitor of chikungunya virus with low micromolar activity. Synonyms: (E)-2-Mercapto-5-(2-Nitrobenzylidene)Thiazol-4(5H)-One; O-Nitrobenzalrhodanin. Grades: 98%. CAS No. 6308-22-1. Molecular formula: C10H6N2O3S2. Mole weight: 266.3. | |
Akrobomycin Quick inquiry Where to buy | It is produced by the strain of Actinomadura reseoviolacea 129-AVI. It has anti-gram-negative bacteria, ringworm and tumor activity. Synonyms: 9,10-Anhydro-13-deoxocarminomycin; 5,12-Naphthacenedione, 10-((3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-8-ethyl-9,10-dihydro-1,6,11-trihydroxy-, (S)-; DTXSID601008673; LS-94000; 3-Ethyl-5,10,12-trihydroxy-6,11-dioxo-1,2,6,11-tetrahydrotetracen-1-yl 3-amino-2,3,6-trideoxyhexopyranoside; Akrobomycin; Rubomycin Q1. CAS No. 89156-94-5. Molecular formula: C26H27NO8. Mole weight: 481.49. | |
Akt1 and Akt2-IN-1 Quick inquiry Where to buy | Akt1 and Akt2-IN-1 is an allosteric inhibitor of Akt1 and Akt2 with the IC50 of 3.5 nM and 42 nM respectively. It has potent and balanced activity. It is dependent on the PH-domain for Akt inhibition. It is selective for Akt1/2 over Akt3 and is highly selective over other members of the AGC family of kinases in vitro. It has potent inhibitory activity against Akt1 and Akt 2 in vivo in a mouse lung and efficacy in a tumor xenograft model. It has moderate activity in an hERG binding assay and is a substrate for human P-glycoprotein. It also shows good physical properties with a human plasma protein binding. Uses: Akt1 and akt2-in-1 has potent inhibitory activity against akt1 and akt 2 and efficacy in a tumor xenograft model. Synonyms: Akt Inhibitor 17; Akti_2008; Akti 2008; Akti2008; Akti-2008; Akt Inhibitor 17; Akt-Inhibitor-17; AktInhibitor17; 3-Phenyl-2-[4-[[4-[5-(2-pyridinyl)-1H-1,2,4-triazol-3-yl]-1-piperidinyl]methyl]phenyl]-1,6-Naphthyridin-5(6H)-one;Akti_2008;3-phenyl-2-[4-[[4-(3-pyridin-2-yl-1H-1,2,4-triazol-5-yl)piperidin-1-yl]methyl]phenyl]-6H-1,6-naphthyridin-5-one. Grades: >98%. CAS No. 893422-47-4. Molecular formula: C33H29N7O. Mole weight: 539.63. | |
AKTide-2T Quick inquiry Where to buy | AKTide-2T, a peptide substrate for Akt/PKB, has been found to act as an inhibitor and mimics the optimal phosphorylation sequence of Akt. Synonyms: AKTide-2T; 324029-01-8; ARKRERTYSFGHHA; AKOS024457090; PD079315. Grades: ≥95% by HPLC. CAS No. 324029-01-8. Molecular formula: C74H114N28O20. Mole weight: 1715.89. | |
Akt Inhibitor IV Quick inquiry Where to buy | Akt inhibitor IV is an inhibitor of Akt activation that inhibits Akt-mediated nuclear export of Forkhead box class O transcription factor 1a (FOXO1a; IC50 = 625 nM) and reduces phosphorylation of Akt at Ser473 and Thr308 in a dose-dependent manner. Synonyms: 5-(2-Benzothiazolyl)-3-ethyl-2-[2-(methylphenylamino)ethenyl]-1-phenyl-1H-benzimidazolium iodide. Grades: ≥95%. CAS No. 681281-88-9. Molecular formula: C31H27N4S·I. Mole weight: 614.6. | |
AKT inhibitor VIII Quick inquiry Where to buy | Akt Inhibitor VIII is a cell-permeable quinoxaline compound that has been shown to potently, selectively, allosterically, and reversibly inhibit Akt1, Akt2, and Akt3 activity. It does not exhibit any inhibitory effect against pleckstrin homology (PH) domain-lacking Akts, AGC family kinases, PKA, PKC or SGK. It also prevails over Akt1/Akt2-mediated resistance to chemotherapeutics in tumor cells and has been shown to block basal and stimulated phosphorylation/activation of Akt1/Akt2 in cultured cells and in mice. Synonyms: AKT inhibitor VIII; AKT-inhibitor-VIII; AKT inhibitor-8; AKT-inhibitor-8; Akt-I 1,2; Akti-1/2. Sigma-A6730. 2H-Benzimidazol-2-one, 1,3-dihydro-1-[1-[[4-(6-phenyl-1H-imidazo[4,5-g]quinoxalin-7-yl)phenyl]methyl]-4-piperidinyl]-. Grades: >98%. CAS No. 612847-09-3. Molecular formula: C34H29N7O. Mole weight: 551.64. | |
AKT Kinase Inhibitor Quick inquiry Where to buy | AKT Kinase Inhibitor is a Akt Kinase Inhibitor. Synonyms: 2-Propyn-1-ol, 3-[2-(4-amino-1,2,5-oxadiazol-3-yl)-7-(3-aminopropoxy)-1-ethyl-1H-imidazo[4,5-c]pyridin-4-yl]-. Grades: >98%. CAS No. 842148-40-7. Molecular formula: C16H19N7O3. Mole weight: 357.37. | |
AK-toxin I Quick inquiry Where to buy | It is produced by the strain of Alternaria kikuchiana AS-1223. It's a plant toxin (especially for pear trees). Synonyms: CTK3E8898; (2E,4E,6E)-8-(2-acetamido-3-phenyl-butanoyl)oxy-8-(2-methyloxiran-2-yl)octa-2,4,6-trienoic Acid. Grades: 95%. CAS No. 85146-09-4. Molecular formula: C23H27NO6. Mole weight: 413.46. | |
AK-toxin ll Quick inquiry Where to buy | It is produced by the strain of Alternaria kikuchiana AS-1223. It's a plant toxin (especially for pear trees). Synonyms: L-Phenylalanine, N-acetyl-, 7-carboxy-1-(2-methyloxiranyl)-2,4,6-heptatrienyl ester, (2S-(2R*(1S*,2E,4Z,6E)))-. Grades: 95%. CAS No. 85146-10-7. Molecular formula: C22H25NO6. Mole weight: 399.44. | |
Akt/SKG Substrate Peptide Quick inquiry Where to buy | Akt/SKG Substrate Peptide is a synthetic peptide and used as a substrate for Akt/PKB. It could not be phosphorylated by MAP kinase or p70 S6 kinase activated protein kinase-1. Synonyms: N5-(Diaminomethylene)-L-ornithyl-L-prolyl-N5-(diaminomethylene)-L-ornithyl-L-alanyl-L-alanyl-L-threonyl-L-phenylalanine. CAS No. 276680-69-4. Molecular formula: C36H59N13O9. Mole weight: 817.95. | |
AL-034 Quick inquiry Where to buy | AL-034 is a Toll-like receptor 7 (TLR7) agonist in a phase I clinical trial for the treatment of HBV infections. Uses: The potential treatment of hbv infections. Synonyms: AL-034; AL 034; AL034. | |
AL-072 Quick inquiry Where to buy | AL072 is an antibiotic against Legionella produced by Strepyomyces sp. AL91. It has strong anti-legionella pneumophila activity. CAS No. 168482-44-8. Molecular formula: C41H76O5. Mole weight: 649.04. | |
AL-321 Quick inquiry Where to buy | AL-321 is a bio-active chemical, but no detailed information has been published yet. Synonyms: AL-321; AL321; AL 321; 5-((4-(2-methyl-2-phenylpropoxy)phenyl)methyl)- 2,4-Thiazolidinedione. Grades: 98%. CAS No. 74772-68-2. Molecular formula: C20H21NO3S. Mole weight: 355.45. | |
AL-3803 Quick inquiry Where to buy | AL-3803, a spiro derivative, has been found to have some extent of biological activity in drug researches. Synonyms: AL-3803; AL 3803; AL3803; (-)-AL03152; AC1MIXPX; (-)-AL03152; Spiro(9H-fluorene-9,4'-imidazolidine)-2',5'-dione, 2,7-difluoro-4-methoxy-, (S)-; (9S)-2,7-difluoro-4-methoxyspiro[fluorene-9,5'-imidazolidine]-2',4'-dione. Grades: 98%. CAS No. 145555-03-9. Molecular formula: C16H10F2N2O3. Mole weight: 316.26. | |
AL 6598 Quick inquiry Where to buy | AL 6598 is the isopropyl ester prodrug of AL 6556, a PGD2 receptor agonist that binds to DP receptors with a Ki value of 3.2 μM and demonstrates an EC50 value of 0.80 μM in an in vitro functional assay. Synonyms: propan-2-yl 2-[(Z)-4-[(1R,2R,3R,5R)-5-chloro-2-[(3R)-3-cyclohexyl-3-hydroxypropyl]-3-hydroxycyclopentyl]but-2-enoxy]acetate. Grades: ≥97%. CAS No. 170291-06-2. Molecular formula: C23H39ClO5. Mole weight: 431. | |
AL 8810 Quick inquiry Where to buy | AL 8810 is a prostaglandin F2a analog and a selective FP prostanoid receptor antagonist. AL-8810 produced a concentration-dependent shift in the fluprostenol concentration-response curve, without significantly decreasing the maximal response. AL-8810 has weak agonist potency with EC50 of 261 +/- 44 nM (n = 3) and Emax = 19% (relative to the full FP receptor agonist cloprostenol) in A7r5 cells and EC50 of 186 +/- 63 nM (n = 3) and Emax = 23% in 3T3 fibroblasts. Uses: Prostaglandin antagonists. Synonyms: AL-8810; 246246-19-5; AL 8810; AL8810; (Z)-7-[(1R,2R,3S,5S)-2-[(E,3R)-3-(2,3-dihydro-1H-inden-2-yl)-3-hydroxyprop-1-enyl]-3-fluoro-5-hydroxycyclopentyl]hept-5-enoic acid; 12QE8J6004; 5-Heptenoic acid, 7-((1R,2R,3S,5S)-2-((1E,3R)-3-(2,3-dihydro-1H-inden-2-yl)-3-hydroxy-1-propen-1-yl)-3-fluoro-5-hydroxycyclopentyl)-, (5Z)-; 5-Heptenoic acid, 7-[(1R,2R,3S,5S)-2-[(1E,3R)-3-(2,3-dihydro-1H-inden-2-yl)-3-hydroxy-1-propen-1-yl]-3-fluoro-5-hydroxycyclopentyl]-, (5Z)-; 5-Heptenoic acid, 7-((1R,2R,3S,5S)-2-((1E,3R)-3-(2,3-dihydro-1H-inden-2-yl)-3-hydroxy-1-propenyl)-3-fluoro-5-hydroxycyclopentyl)-, (5Z)-. Grades: ≥98%. CAS No. 246246-19-5. Molecular formula: C24H31O4F. Mole weight: 402.5. | |
AL 8810 isopropyl ester Quick inquiry Where to buy | AL 8810 is a prostaglandin F2a analog and a selective FP prostanoid receptor antagonist. AL 8810 isopropyl ester is a lipid soluble, esterified prodrug form of AL 8810 analogous to the commonly used therapeutic intraocular prostaglandin compounds such as Latanoprost and Travoprost. Synonyms: AL 8810 isopropyl ester; Propan-2-yl (Z)-7-[(1R,2R,3S,5S)-2-[(E,3R)-3-(2,3-dihydro-1H-inden-2-yl)-3-hydroxyprop-1-enyl]-3-fluoro-5-hydroxycyclopentyl]hept-5-enoate; 5-Heptenoic acid, 7-[(1R,2R,3S,5S)-2-[(1E,3R)-3-(2,3-dihydro-1H-inden-2-yl)-3-hydroxy-1-propen-1-yl]-3-fluoro-5-hydroxycyclopentyl]-, 1-methylethyl ester, (5Z)-; HMS3648C21; AKOS025294879; SR-01000946200; SR-01000946200-1; 9alpha, 15R- dihydroxy- 11beta- fluoro- 15- (2, 3- dihydro- 1H- inden- 2- yl)- 16, 17, 18, 19, 20- pentanor- prosta- 5Z, 13E- dien- 1- oic acid, isopropyl ester. Grades: ≥98%. CAS No. 208114-93-6. Molecular formula: C27H37FO4. Mole weight: 444.6. | |
AL 8810 methyl ester Quick inquiry Where to buy | AL 8810 is a prostaglandin F2a analog and a selective FP prostanoid receptor antagonist. AL 8810 methyl ester is a lipid soluble, esterified prodrug form of AL 8810 analogous to the commonly used therapeutic intraocular prostaglandin compounds such as Latanoprost and Travoprost. Synonyms: AL 8810 methyl ester; 1176541-11-9; methyl (Z)-7-[(1R,2R,3S,5S)-2-[(E,3R)-3-(2,3-dihydro-1H-inden-2-yl)-3-hydroxyprop-1-enyl]-3-fluoro-5-hydroxycyclopentyl]hept-5-enoate; CHEBI:186084; DTXSID001347566; methyl (Z)-7-[(1R,2R,3S,5S)-2-[(E,3R)-3-(2,3-dihydro-1H-inden-2-yl)-3-hydroxyprop-1-enyl]-3-luoro-5-hydroxycyclopentyl]hept-5-enoate. Grades: ≥98%. CAS No. 1176541-11-9. Molecular formula: C25H33FO4. Mole weight: 416.5. | |
Ala-Ala-OH Quick inquiry Where to buy | Synonyms: L-Alanyl-L-alanine. Grades: ≥ 98% (HPLC). CAS No. 1948-31-8. Molecular formula: C6H12N2O3. Mole weight: 160.17. | |
Ala-Ala-OMe HCl Quick inquiry Where to buy | Substrate for dipeptidyl aminopeptidase I (cathepsin C). Synonyms: L-Alanyl-L-alanine methyl ester hydrochloride. Grades: ≥ 98% (TLC). CAS No. 41036-19-5. Molecular formula: C7H14N2O3·HCl. Mole weight: 210.66. | |
Ala-Ala-Phe-pNA Quick inquiry Where to buy | Substrate for chymotrypsin and tripeptidyl peptidase I. Synonyms: Ala-Ala-Phe p-nitroanilide. Grades: ≥ 99% (Assay). CAS No. 61043-41-2. Molecular formula: C21H25N5O5. Mole weight: 427.46. | |
a-Lactose monohydrate Quick inquiry Where to buy | It is widely used as a carrier, diluent, and flow aid in dry powder inhalation formulations. Synonyms: O-b-D-galactopyranosyl-(1-4)-a-D-glucopyranose monohydrate. Grades: ≥98%. CAS No. 5989-81-1. Molecular formula: C12H22O11.H2O. Mole weight: 360.31. | |
Ala-D-Ala-OH Quick inquiry Where to buy | Synonyms: L-Alanyl-D-alanine. Grades: ≥ 97% (HPLC). CAS No. 3695-80-5. Molecular formula: C6H12N2O3. Mole weight: 160.17. | |
Aladapcin Quick inquiry Where to buy | It is produced by the strain of Nocardia sp. SANK 60484. Alanine in 1-100 ?/kg can enhance the resistance of mice against experimental E. coli infection. Synonyms: SCHEMBL4061749; DTXSID90921412; N-{2-[(2,6-Diamino-1,7-dihydroxy-7-iminoheptylidene)amino]-1-hydroxypropylidene}alanine. Grades: 95%. CAS No. 114540-27-1. Molecular formula: C13H25N5O5. Mole weight: 331.37. | |
ALA-D-GAMMA-GLU-LYS-D-ALA-D-ALA Quick inquiry Where to buy | Synonyms: ALA-D-GAMMA-GLU-LYS-D-ALA-D-ALA; ala-D-G-glu-lys-D-ala-D-ala; ala-d-γ-glu-lys-d-ala-d-ala. CAS No. 2614-55-3. Molecular formula: C20H36N6O8. Mole weight: 488.54. | |
Aladorian Quick inquiry Where to buy | Aladorianis is a ryanodine receptor calcium release channel modulator. It is an antiarrhythmic agent. Clinical development for Chronic heart failure and Ventricular tachycardia was discontinued. Uses: Chronic heart failure; ventricular tachycardia. Synonyms: 2,3-Dihydro-7-methoxy-α-oxo-1,4-benzothiazepine-4(5H)-acetic Acid; ARM036; ARM-036; ARM 036; S36; S44121-1; Aladorian; Aladorian; S 36; S 44121-1. Grades: 98%. CAS No. 865433-00-7. Molecular formula: C12H13NO4S. Mole weight: 267.30. | |
Ala-Gln-OH Quick inquiry Where to buy | White or off White crystalline powder. Synonyms: L-Alanine-L-glutamine. Grades: ≥ 99% (HPLC). CAS No. 39537-23-0. Molecular formula: C8H15N3O4. Mole weight: 217.22. | |
Ala-Gly-Gly-Gly-OH Quick inquiry Where to buy | Grades: ≥ 99%. CAS No. 5123-42-2. Molecular formula: C9H16N4O5. Mole weight: 260.25. | |
Ala-Gly-NH2 HCl Quick inquiry Where to buy | Synonyms: L-Alanyl glycine amide hydrochloride. Grades: ≥ 99% (TLC). CAS No. 71431-66-8. Molecular formula: C5H11N3O2·HCl. Mole weight: 181.62. |