BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Abanoquil mesilate | This molecular is an active biochemical as a Alpha 1 adrenergic receptor antagonist. However, no developments were reported for Ischaemic heart disorders and Arrhythmias. Uses: Arrhythmias; ischaemic heart disorders. Synonyms: 2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-6,7-dimethoxyquinolin-4-amine; methanesulfonic acid,TCMDC-131968, TCMDC 131968, TCMDC131968, UK 52046; UK-52046; UK52046; Abanoquil. Grade: 98%. CAS No. 118931-00-3. Molecular formula: C23H29N3O7S. Mole weight: 491.56. |  |
| Abaperidone | Abaperidone is a potent 5-HT2A receptor and dopamine D2 receptor antagonist with IC50s of 6.2 and 17 nM, respectively. Synonyms: 7-(3-(4-(6-Fluoro-1,2-benzisoxazol-3-yl)piperidino)propoxy)-3-(hydroxymethyl)-4H-1-benzopyran-4-one; 4H-1-Benzopyran-4-one, 7-[3-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]propoxy]-3-(hydroxymethyl)-. Grade: 95%. CAS No. 183849-43-6. Molecular formula: C25H25FN2O5. Mole weight: 452.47. | |
| Abarelix | Abarelix is a synthetic decapeptide and antagonist of naturally occurring gonadotropin-releasing hormone (GnRH). Abarelix directly and competitively binds to and blocks the gonadotropin releasing hormone receptor in the anterior pituitary gland, thereby inhibiting the secretion and release of luteinizing hormone (LH) and follicle stimulating hormone (FSH). In males, the inhibition of LH secretion prevents the release of testosterone. As a result, this may relieve symptoms associated with prostate hypertrophy or prostate cancer, since testosterone is required to sustain prostate growth. Check for active clinical trials or closed clinical trials using this agent. Synonyms: Plenaxis, PPI-149; PPI 149; PPI149; R-3827; R 3827; R3827. Grade: 98%. CAS No. 183552-38-7. Molecular formula: C72H95ClN14O14. Mole weight: 1416.09. | |
| Abasic II phosphoramidite | Abasic II Phosphoramidite, a highly valuable chemical compound, plays a pivotal role in oligonucleotide synthesis, particularly in the context of medicinal applications, as it affords the unique ability to generate modified nucleic acids that combat cancer and genetic disorders. This innovative compound is exceedingly crucial in the biomedical sphere as it transforms the course of advanced therapeutics. Synonyms: 5-O-Dimethoxytrityl-1-O-tert-butyldimethylsilyl-2-deoxyribose-3-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; α-D-erythro-Pentofuranose, 5-O-[bis(4-methoxyphenyl)phenylmethyl]-2-deoxy-1-O-[(1,1-dimethylethyl)dimethylsilyl]-, 3-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]. Grade: ≥95%. CAS No. 1835233-43-6. Molecular formula: C41H59N2O7PSi. Mole weight: 750.98. | |
| Abatacept | Abatacept is a soluble fusion protein consisting of the extra-cellular domain of human CTLA4 and a fragment of the Fc portion of human IgG1 (hinge and CH2 and 3 domains). It is a selective T-cell co-stimulation modulator and a protein drug for the autoimmune diseases. Synonyms: CTLA4lg. CAS No. 332348-12-6. | |
| Abbeymycin | Abbeymycin is an antibiotic isolated from the Streptomyces sp. AB-999F52. Abbeymycin has weak antibacterial activity against several anaerobic bacteria (such as Bacteroides fragilis, Bacteroides polymorpha, Peptococcus and Peptostreptococcus, etc.). Synonyms: (2S,11S,11aS)-2-Hydroxy-11-methoxy-1,2,3,10,11,11a-hexahydro-5H-pyrrolo[2,1-c][1,4]benzodiazepin-5-one; (2S)-2α-Hydroxy-11β-methoxy-1,2,3,10,11,11aβ-hexahydro-5H-pyrrolo[2,1-c][1,4]benzodiazepin-5-one; 5H-Pyrrolo[2,1-c][1,4]benzodiazepin-5-one, 1,2,3,10,11,11a-hexahydro-2-hydroxy-11-methoxy-, (2S,11S,11aS)-; 5H-Pyrrolo(2,1-c)(1,4)benzodiazepin-5-one, 1,2,3,10,11,11a-hexahydro-2-hydroxy-11-methoxy-, (2S-(2-α,11-β,11a-β))-. Grade: 95%. CAS No. 108073-64-9. Molecular formula: C13H16N2O3. Mole weight: 248.28. | |
| Abbott 72517; Zankiren hydrochloride | Abbott 72517; Zankiren hydrochloride. CAS No. 138810-64-7. Molecular formula: C35H56ClN5O6S2. Mole weight: 742.4. | |
| ABBV-167 | ABBV-167 is a phosphate prodrug of venetoclax, a Bcl-2 inhibitor. Synonyms: Benzamide, 4-(4-((2-(4-chlorophenyl)-4,4-dimethyl-1-cyclohexen-1-yl)methyl)-1-piperazinyl)-N-((3-nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)phenyl)sulfonyl)-2-((7-((phosphonooxy)methyl)-7H-pyrrolo(2,3-b)pyridin-5-yl)oxy)-; (5-{5-(4-{[2-(4-Chlorophenyl)-4,4-dimethyl-1-cyclohexen-1-yl]methyl}-1-piperazinyl)-2-[({3-nitro-4-[(tetrahydro-2H-pyran-4-ylmethyl)amino]phenyl}sulfonyl)carbamoyl]phenoxy}-7H-pyrrolo[2,3-b]pyridin-7-yl)methyl dihydrogen phosphate. CAS No. 1351456-78-4. Molecular formula: C46H53ClN7O11PS. Mole weight: 978.45. | |
| ABBV-4083 | ABBV-4083 is an analog of Tylosin A and it has potent anti-Wolbachia and anti-filarial activities. Synonyms: 4''-(p-Fluorobenzyl)tylosin A; Flubentylosin; 4b-O-((4-Fluorophenyl)methyl)tylosin. CAS No. 1809266-03-2. Molecular formula: C53H82FNO17. Mole weight: 1024.23. | |
| ABBV-744 | ABBV-744 is a BDII-selective BET bromodomain inhibitor that inhibits BRD2, BRD3 and BRD4. It is developed for treating AML and cancers. Synonyms: N-ethyl-4-(2-(4-fluoro-2,6-dimethylphenoxy)-5-(2-hydroxypropan-2-yl)phenyl)-6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridine-2-carboxamide. Grade: ≥98%. CAS No. 2138861-99-9. Molecular formula: C28H30FN3O4. Mole weight: 491.55. | |
| ABBV-CLS-484 | ABBV-CLS-484 is a PTPN2 inhibitor under a Phase 1 clinical trial for the treatment of advanced solid tumors. Molecular formula: C17H24FN3O4S. Mole weight: 385.45. | |
| ABC-1183 | ABC-1183 is an inhibitor of glycogen synthase kinase 3 (GSK-3) alpha, glycogen synthase kinase 3 (GSK-3) beta and cyclin dependent kinase 9 (CDK-9). It can induce cell apoptosis and various signaling pathways. ABC-1183 shows toxicity to many cell lines in humans and mice. Synonyms: ABC1183; ABC 1183; NSC797769; NSC-797769. Grade: > 99% by HPLC. CAS No. 1042735-18-1. Molecular formula: C18H14N4OS. Mole weight: 334.39. | |
| ABC294640 | ABC294640 is an orally available, aryladamantane compound and selective inhibitor of sphingosine kinase-2 (SK2) with potential antineoplastic activity. Upon administration, ABC294640 competitively binds to and inhibits SK2, thereby preventing the phosphorylation of the pro-apoptotic amino alcohol sphingosine to sphingosine 1-phosphate (S1P), the lipid mediator that is pro-survival and critical for immunomodulation. Synonyms: ABC-294640; ABC294640; ABC 294640; Opaganib; 3-(4-chlorophenyl)-adamantane-1-carboxylic acid (pyridin-4-ylmethyl)amide. Grade: 0.98. CAS No. 915385-81-8. Molecular formula: C23H25ClN2O. Mole weight: 380.9104. | |
| ABC294735 | ABC294735 is a dual SK1/SK2 inhibitor with potential anticancer activity. Synonyms: ABC-294735; ABC 294735. Grade: >98%. CAS No. 917236-13-6. Molecular formula: C24H26ClNO3. Mole weight: 411.92. | |
| ABC34 | ABC34 is an inactive control probe for JJH260 , the inhibitor of androgen-induced gene 1 (AIG1), an enzyme that hydrolyzes fatty acid esters of hydroxy fatty acids (FAHFAs). Synonyms: 1,3-dioxo-7-(4-phenoxybenzyl)hexahydroimidazo[1,5-a]pyrazin-2(3H)-yl 4-(4-methoxyphenyl)piperazine-1-carboxylate. Grade: ≥98%. CAS No. 1831135-56-8. Molecular formula: C31H33N5O6. Mole weight: 571.6. | |
| ABC99 | ABC99 is an N-hydroxyhydantoin (NHH) carbamate that inhibits the Wnt-deacylating enzyme NOTUM (IC50 = 13 nM). It preserves Wnt3A signaling in the presence of NOTUM (EC50 = 89 nM in a cell-based reporter assay). Grade: ≥95%. CAS No. 2331255-53-7. Molecular formula: C22H21ClN4O5. Mole weight: 456.9. | |
| ABCB1 | ABCB1, a CXC receptor ligand from the extracellular matrix (ECM), is produced during airway inflammation. Its activity links ECM degradation to neutrophil recruitment in airway inflammation. It may be a biomarker and therapeutic target for neutrophil inflammatory diseases. Synonyms: Ac-PGP; Ac-Pro-Gly-Pro-OH; Acetyl Pro-Gly-Pro-OH; N-acetyl-L-prolyl-glycyl-L-proline; N-α-PGP. Grade: 95%. CAS No. 292171-04-1. Molecular formula: C14H21N3O5. Mole weight: 311.34. | |
| Abciximab | Abciximab is a Fab fragment of the chimeric human-murine monoclonal antibody 7E3, which binds to the platelet glycoprotein IIb/IIIa receptor and inhibits platelet aggregation. Synonyms: ReoPro. Grade: 95%. CAS No. 143653-53-6. | |
| ABD459 | ABD459 is a neutral antagonist of the central cannabinoid 1 (CB1) receptor (Ki = 8.6 nM). Synonyms: [5-(4-bromophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazol-3-yl](4-methoxyphenyl)-methanone. Grade: ≥95%. CAS No. 1047670-51-8. Molecular formula: C24H17BrCl2N2O2. Mole weight: 516.2. | |
| ABEI | It is a highly efficient chemiluminescent NH2-coupling reagent for detection of a wide variety of proteins, even up to the picomole range, and has significant advantages over traditional radioimmunoassays. Synonyms: N-(4-Aminobutyl)-N-ethylisoluminol; 6-(N-(4-Aminobutyl)-N-ethyl)amino-2,3-dihydrophthalazine-1,4-dione; 4-(N1-Ethyl-4-aminobutylamino)phthalic hydrazide. Grade: ≥90%. CAS No. 66612-29-1. Molecular formula: C14H20N4O2. Mole weight: 276.33. | |
| ABEI-DSC | It is a highly efficient chemiluminescent COO-coupling reagent for detection of a wide variety of proteins, even up to the picomole range, and has significant advantages over traditional radioimmunoassays. Synonyms: 2,5-dioxopyrrolidin-1-yl (4-((1,4-dioxo-1,2,3,4-tetrahydrophthalazin-6-yl)(ethyl)amino)butyl)carbamate. Grade: ≥95%. Molecular formula: C19H23N5O6. Mole weight: 417.42. | |
| Abelacimab | Abelacimab. CAS No. 2098724-83-3. | |
| Abemaciclib | Abemaciclib is an orally available cyclin-dependent kinase (CDK) inhibitor that targets the CDK4 (cyclin D1) and CDK6 (cyclin D3) cell cycle pathway, with potential antineoplastic activity. It is used for the treatment of advanced or metastatic breast cancers. Synonyms: LY-2835219; LY 2835219; LY2835219; Verzenio; N-[5-[(4-ethylpiperazin-1-yl)methyl]pyridin-2-yl]-5-fluoro-4-(7-fluoro-2-methyl-3-propan-2-ylbenzimidazol-5-yl)pyrimidin-2-amine. Grade: ≥98%. CAS No. 1231929-97-7. Molecular formula: C27H32F2N8. Mole weight: 506.61. | |
| Abemaciclib-[13C4,15N2] | Abemaciclib-[13C4,15N2] is a labelled Abemaciclib. Abemaciclib is an orally available cyclin-dependent kinase (CDK) inhibitor that targets the CDK4 (cyclin D1) and CDK6 (cyclin D3) cell cycle pathway, with potential antineoplastic activity. It is used for the treatment of advanced or metastatic breast cancers. Synonyms: N-(5-((4-ethylpiperazin-1-yl-2,3,5,6-13C4-1,4-15N2)methyl)pyridin-2-yl)-5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyrimidin-2-amine-[13C4,15N2]. Grade: ≥99% atom 13C; ≥98% atom 15N. Molecular formula: C23[13C]4H32F2N6[15N]2. Mole weight: 512.56. | |
| Abemaciclib-[d10] | Labelled Abemaciclib. Abemaciclib is an orally available cyclin-dependent kinase (CDK) inhibitor that targets the CDK4 (cyclin D1) and CDK6 (cyclin D3) cell cycle pathway, with potential antineoplastic activity. It is used for the treatment of advanced or metastatic breast cancers. Synonyms: N-(5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-yl)-5-fluoro-4-(4-fluoro-2-(methyl-d3)-1-(propan-2-yl-d7)-1H-benzo[d]imidazol-6-yl)pyrimidin-2-amine; Abemaciclib D10; N-[5-[(4-Ethyl-1-piperazinyl)methyl]-2-pyridinyl]-5-fluoro-4-[4-fluoro-2-(methyl-d3)-1-[1-(methyl-d3)ethyl-1,2,2,2-d4]-1H-benzimidazol-6-yl]-2-pyrimidinamine; LY-2835219-d10; N-[5-[(4-Ethyl-1-piperazinyl)methyl]-2-pyridinyl]-5-fluoro-4-[4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimidazol-6-yl]-2-pyrimidinamine-d10. Grade: >95%. CAS No. 2088650-71-7. Molecular formula: C27H22D10F2N8. Mole weight: 516.66. | |
| Abemaciclib-[d5] | Labelled Abemaciclib. Abemaciclib is an orally available cyclin-dependent kinase (CDK) inhibitor that targets the CDK4 (cyclin D1) and CDK6 (cyclin D3) cell cycle pathway, with potential antineoplastic activity. It is used for the treatment of advanced or metastatic breast cancers. Synonyms: N-[5-[(4-Ethyl-1-piperazinyl)methyl]-2-pyridinyl]-5-fluoro-4-[4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimidazol-6-yl]-2-pyrimidinamine-d5; N-(5-((4-ethylpiperazin-1-yl)methyl)pyridin-2-yl)-5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyrimidin-2-amine-d5. Grade: > 98%. CAS No. 1809251-51-1. Molecular formula: C27H27D5F2N8. Mole weight: 511.62. | |
| Abemaciclib-[d7] | Labelled Abemaciclib. Abemaciclib is an orally available cyclin-dependent kinase (CDK) inhibitor that targets the CDK4 (cyclin D1) and CDK6 (cyclin D3) cell cycle pathway, with potential antineoplastic activity. It is used for the treatment of advanced or metastatic breast cancers. Synonyms: N-(5-((4-ethylpiperazin-1-yl)methyl)pyridin-2-yl)-5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyrimidin-2-amine-d7. Grade: > 98%. Molecular formula: C27H25D7F2N8. Mole weight: 513.64. | |
| Abemaciclib-[d8] | Labelled Abemaciclib. Abemaciclib is an orally available cyclin-dependent kinase (CDK) inhibitor that targets the CDK4 (cyclin D1) and CDK6 (cyclin D3) cell cycle pathway, with potential antineoplastic activity. It is used for the treatment of advanced or metastatic breast cancers. Synonyms: N-(5-((4-Ethylpiperazin-1-yl-2,2,3,3,5,5,6,6-d8)methyl)pyridin-2-yl)-5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyrimidin-2-amine; Abemaciclib D8; [d8]-Abemaciclib; [d8]-LY-2835219; LY-2835219-d8. Grade: ≥90%. CAS No. 2088650-53-5. Molecular formula: C27H24D8F2N8. Mole weight: 514.65. | |
| Abemaciclib Impurity 1-[d12] | Abemaciclib Impurity 1-[d12] is a labelled impurity of Abemaciclib. Abemaciclib is an orally available cyclin-dependent kinase (CDK) inhibitor that targets the CDK4 (cyclin D1) and CDK6 (cyclin D3) cell cycle pathway, with potential antineoplastic activity. It is used for the treatment of advanced or metastatic breast cancers. Synonyms: 6-Bromo-4-fluoro-1-isopropyl-2-methyl-1h-benzo[d]imidazole-D12. Grade: > 98%. Molecular formula: C11D12BrFN2. Mole weight: 283.20. | |
| Abemaciclib Impurity 1-[d5] | Abemaciclib Impurity 1-[d5] is a labelled impurity of Abemaciclib. Abemaciclib is an orally available cyclin-dependent kinase (CDK) inhibitor that targets the CDK4 (cyclin D1) and CDK6 (cyclin D3) cell cycle pathway, with potential antineoplastic activity. It is used for the treatment of advanced or metastatic breast cancers. Synonyms: 6-Bromo-4-fluoro-1-isopropyl-2-methyl-1h-benzo[d]imidazole-d5. Grade: > 98%. Molecular formula: C11H7D5BrFN2. Mole weight: 276.16. | |
| Abemaciclib Impurity 5-[d5] | Abemaciclib Impurity 5-[d5] is a labelled impurity of Abemaciclib. Abemaciclib is an orally available cyclin-dependent kinase (CDK) inhibitor that targets the CDK4 (cyclin D1) and CDK6 (cyclin D3) cell cycle pathway, with potential antineoplastic activity. It is used for the treatment of advanced or metastatic breast cancers. Synonyms: 1-[(6-bromopyridin-3-yl)methyl]-4-ethylpiperazine-d5. Grade: > 98%. CAS No. 1809251-58-8. Molecular formula: C12H13D5BrN3. Mole weight: 289.23. | |
| abemaciclib mesylate | Abemaciclib mesylate is a CDK inhibitor with selectivity for CDK4 and CDK6. It was approved for the treatment of advanced or metastatic breast cancers. Uses: The treatment of advanced or metastatic breast cancers. Synonyms: Verzenio; LY2835219; LY 2835219; LY-2835219; UNII-KKT462Q807; Abemaciclib methanesulfonate; N-(5-((4-ethylpiperazin-1-yl)methyl)pyridin-2-yl)-5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyrimidin-2-amine methanesulfonate. CAS No. 1231930-82-7. Molecular formula: C28H36F2N8O3S. Mole weight: 602.706. | |
| Abemaciclib metabolite M18 hydrochloride | Abemaciclib metabolite M18 (LSN3106729) hydrochloride, derived from Abemaciclib, is an antitumor CDK inhibitor. It has been utilized alongside a CRBN ligand to design a PROTAC CDK4/6 degrader. Molecular formula: C25H29ClF2N8O. Mole weight: 531. | |
| Abemaciclib metabolite M2 | Abemaciclib metabolite M2, a metabolite of Abemaciclib, is a potent inhibitor of CDK4 and CDK6 with IC50s of 1-3 nM. It has anticancer activity. Synonyms: LSN2839567; 5-Fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzimidazol-6-yl)-N-[5-(1-piperazinylmethyl)-2-pyridinyl]-2-pyrimidinamine; 2-Pyrimidinamine, 5-fluoro-4-[4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimidazol-6-yl]-N-[5-(1-piperazinylmethyl)-2-pyridinyl]-. Grade: ≥95%. CAS No. 1231930-57-6. Molecular formula: C25H28F2N8. Mole weight: 478.54. | |
| Abemaciclib metabolite M20 | Abemaciclib metabolite M20, an active metabolite of Abemaciclib, is a selective CDK4/6 inhibitor for cancer treatment. Synonyms: LSN3106726; ?2-Methanol Abemaciclib; CDK4/6-IN-4; {6-[2-({5-[(4-Ethyl-1-piperazinyl)methyl]-2-pyridinyl}amino)-5-fluoro-4-pyrimidinyl]-4-fluoro-1-isopropyl-1H-benzimidazol-2-yl}methanol; 1H-Benzimidazole-2-methanol, 6-[2-[[5-[(4-ethyl-1-piperazinyl)methyl]-2-pyridinyl]amino]-5-fluoro-4-pyrimidinyl]-4-fluoro-1-(1-methylethyl)-. Grade: ≥98%. CAS No. 2138499-06-4. Molecular formula: C27H32F2N8O. Mole weight: 522.59. | |
| Abeprazan | Abeprazan inhibits H+, K+- ATPase by reversible potassium-competitive ionic binding with no acid activation required. Abeprazan is used for the treatment of 5-HT receptor or muscarinic acetylcholine receptor-mediated diseases. Synonyms: Fexuprazan; 5-(2,4-Difluorophenyl)-1-[(3-fluorophenyl)sulfonyl]-4-methoxy-N-methyl-1H-pyrrole-3-methanamine; DWP14012; DWP-14012. Grade: 99%. CAS No. 1902954-60-2. Molecular formula: C19H17F3N2O3S. Mole weight: 410.41. | |
| Abeprazan hydrochloride | Abeprazan inhibits H+, K+- ATPase by reversible potassium-competitive ionic binding with no acid activation required. Abeprazan is used for the treatment of 5-HT receptor or muscarinic acetylcholine receptor-mediated diseases. Synonyms: DWP14012 hydrochloride; Fexuprazan hydrochloride. CAS No. 1902954-87-3. Molecular formula: C19H18ClF3N2O3S. Mole weight: 446.87. | |
| ABERCHROME 670 | ABERCHROME 670. Synonyms: 2-(2-ADAMANTYLIDENE)-3-[1-(2,5-DIMETHYL-3-FURANYL)ETHYLIDENE]-SUCCINANHYDRIDE; ABERCHROME 670. Grade: 95%. CAS No. 94856-25-4. Molecular formula: C22H24O4. Mole weight: 352.42. | |
| ABET | Arecaidine But-2-ynyl Ester Tosylate (ABET) is a potent and selective agonist of M2 recceptors in the atrium versus those in the ileum. Synonyms: Arecaidine but-2-ynyl ester tosylate; N-Methyl-1'2'5'6-tetrahydropyridine-3-carboxylic acid but-2-ynyl ester tosylate. CAS No. 119630-77-2. Molecular formula: C18H23NO5S. Mole weight: 365.444. | |
| Abexinostat | Abexinostat, also known as PCI-24781 or CRA-024781, is a novel, broad-spectrum hydroxamic acid-based inhibitor of histone deacetylase (HDAC) with potential antineoplastic activity. Abexinostat inhibits several isoforms of HDAC, resulting in an accumulation of highly acetylated histones, followed by the induction of chromatin remodeling. Synonyms: CRA-024781; CRA 024781; CRA024781; PCI-24781; PCI24781; PCI 24781. Grade: 98%. CAS No. 783355-60-2. Molecular formula: C21H23N3O5. Mole weight: 397.431. | |
| ABH | ABH is an inhibitor of arginase types I and II. Synonyms: Amino-2-borono-6-hexanoic acid; (S)-2-amino-6-boronohexanoic acid. Grade: ≥90%. CAS No. 222638-65-5. Molecular formula: C6H14BNO4. Mole weight: 175. | |
| ABI-010 | ABI-010 is the nanoparticle albumin-bound 17-AAG. Synonyms: ABI-010; ABI 010; ABI010. | |
| Abierixin | Abierixin is a polyether antibiotic isolated from Streptomyces albus NRRL B-1865. Abierixin exhibited weak antimicrobial and ionophorous activities, low toxicity but good anticoccidial activity. Synonyms: Nigericin, 3,7-deepoxy-2,3-didehydro-7-hydroxy-; (2E)-7-hydroxy-8-(2-{5'-[6-hydroxy-6-(hydroxymethyl)-3,5-dimethyltetrahydro-2H-pyran-2-yl]-2,3'-dimethyloctahydro-2,2'-bifuran-5-yl}-9-methoxy-2,4,10-trimethyl-1,6-dioxaspiro[4.5]dec-7-yl)-2,4-dimethyloct-2-enoic acid. CAS No. 100634-16-0. Molecular formula: C40H68O11. Mole weight: 724.96. | |
| Abiesadine I | Abiesadine I is an eminent natural compound manifesting remarkable potential in studying diverse malignancies. Sourced from the Abies tree, this groundbreaking product orchestrates resolute antitumor mechanisms, specifically honed to assail malignant cells. E. Synonyms: 4-[(15-Hydroxyabieta-8,11,13-trien-18-yl)oxy]-4-oxobutanoic acid. Grade: 96.0%. CAS No. 1210347-50-4. Molecular formula: C24H34O5. Mole weight: 402.52. | |
| Abiesadine N | Abiesadine N is isolated from the barks of Pinus yunnanensis. Uses: Anti-inflammatory activity. Synonyms: 15-Methoxyabieta-8,11,13-trien-18-oic acid. Grade: 97.5%. CAS No. 1159913-80-0. Molecular formula: C21H30O3. Mole weight: 330.5. | |
| ABIES ALBA LEAF OIL | ABIES ALBA LEAF OIL. Synonyms: ABIES ALBA LEAF OIL; ABIES PECTINATA OIL; Oils, silver fir; EUROPEANSILVERFIR; TEMPLINOIL; ABIESALBAOIL(CONES); ABIESALBAOILFROMCONES; ABIESALBACONEOIL. Grade: 95%. CAS No. 8021-27-0. | |
| Abiesinol F | Abiesinol F isolated from the herbs of Abies ernestii. Synonyms: 2''-epi-Abiesinol E. Grade: > 95%. CAS No. 1190070-91-7. Molecular formula: C30H22O10. Mole weight: 542.5. | |
| Abieta-8,11,13-triene-7,15,18-triol | Abieta-8,11,13-triene-7,15,18-triol is a remarkable bioactive constituent sourced from botanical origins aiding in studying a multitude of ailments, encompassing cancer, inflammatory conditions and microbial assaults. Synonyms: Abieta-8; 18-triol; 13-triene-7. Grade: 95.0%. CAS No. 337527-10-3. Molecular formula: C20H30O3. Mole weight: 318.4504. | |
| Abietane | Abietane is a diterpene product found in Croton tricolor and Croton argyrophyllus. Synonyms: (-)-Abietane; Phenanthrene, tetradecahydro-1,1,4a-trimethyl-7-(1-methylethyl)-, (4aR,4bS,7S,8aS,10aS)-; (4aR,4bα,7α,8aβ,10aα)-Tetradecahydro-1,1,4a-trimethyl-7-(1-methylethyl)phenanthrene; 13α-Isopropylpodocarpane. Grade: ≥95%. CAS No. 19407-12-6. Molecular formula: C20H36. Mole weight: 276.50. | |
| Abietatriene | Abietatriene is a diterpene product found in Pinus brutia var. eldarica and Prumnopitys andina. Synonyms: Dehydroabietan; Phenanthrene, 1,2,3,4,4a,9,10,10a-octahydro-1,1,4a-trimethyl-7-(1-methylethyl)-, (4aS,10aS)-; (4aS,10aS)-1,2,3,4,4a,9,10,10a-Octahydro-1,1,4a-trimethyl-7-isopropylphenanthrene; 8,11,13-Abietatriene; Abieta-8,11,13-triene; ar-Abietatriene; (4aS,10aS)-1,2,3,4,4a,9,10,10a-Octahydro-1,1,4a-trimethyl-7-(1-methylethyl)phenanthrene; Phenanthrene, 1,2,3,4,4a,9,10,10a-octahydro-1,1,4a-trimethyl-7-(1-methylethyl)-, (4aS-trans)-; Podocarpa-8,11,13-triene, 13-isopropyl-; (+)-Dehydroabietadiene; Abietane, dehydro-; Dehydroabietane. Grade: ≥95%. CAS No. 19407-28-4. Molecular formula: C20H30. Mole weight: 270.45. | |
| Abietic acid | Abietic acid isolated from the herbs of Pinus massoniana. Uses: Anti-inflammation. Synonyms: (1R,4AR,4BR,10AR)-7-ISOPROPYL-1,4A-DIMETHYL-1,2,3,4,4A,4B,5,6,10,10A-DECAHYDRO-PHENANTHRENE-1-CARBOXYLIC ACID. Grade: 0.95. CAS No. 514-10-3. Molecular formula: C20H30O2. Mole weight: 302.45. | |
| Abietic Acid Diamylamine | Abietic Acid Diamylamine. Synonyms: (1R,4aR,4bR,10aR)-1,2,3,4,4a,4b,5,6,10,10a-Decahydro-1,4a-dimethyl-7-(1-methylethyl)-1-phenanthrenecarboxylic Acid Compd. with N-Pentyl-1-pentanamine; (1R,4aR,4bR,10aR)- 1,2,3,4,4a,4b,5,6,10,10a-Decahydro-1,4a-dimethyl-7-(1-methylethyl)-1-phenanthrenecarboxylic Acid Compd. with N-Pentyl-1-pentanamine. CAS No. 881185-17-7. Molecular formula: C20H30O2·C9H21N. Mole weight: 302.45+(143.27). | |
| ABIETIC ACID ETHYL ESTER | ABIETIC ACID ETHYL ESTER. Synonyms: ETHYL ROSINATE; ETHYL ABIETATE; ABIETIC ACID ETHYL ESTER; ROSIN ACID ETHYL ESTER; ABIETIC ACID ETHYL ESTER 70.0+%; 1-Phenanthrenecarboxylic acid, 1,2,3,4,4a,4b,5,6,10,10a-decahydro-1,4a-dimethyl-7-(1-methylethyl)-, ethyl ester, (1R,4aR,4bR,10aR)-; (1R)-1,2,3,4. Grade: >70.0%(GC). CAS No. 631-71-0. Molecular formula: C22H34O2. Mole weight: 330.5. | |
| Abietic acid glycerol ester | Abietic acid glycerol ester. Synonyms: Abietic acid glycerol ester; Glycerine ester of wood resin; Glycerol ester of rosin. CAS No. 8050-30-4. Molecular formula: C23H36O4. Mole weight: 376.52954. | |
| ABIETIC ACID SODIUM SALT 85+% | ABIETIC ACID SODIUM SALT 85+%. CAS No. 14351-66-7. Molecular formula: C20H29NaO2. Mole weight: 324.43. | |
| Abikoviromycin | Abikoviromycin is an antiviral antibiotic piperidine alkaloid produced by the bacteria Streptomyces abikoensis and Streptomyces rubescens. The dilution of Abikoviromycin has the effect of anti-Eastern and Western equine encephalitis virus, but has no effect on Venezuelan virus. Synonyms: Latumcidin; Abicoviromycin; Cyclopent(b)oxireno(c)pyridine, 7-ethylidene-1a,2,3,7-tetrahydro-, (1aR,7E,7aS)-; Cyclopent(b)oxireno(c)pyridine, 7-ethylidene-1a,2,3,7-tetrahydro-, (1aR-(1aR*,7E,7aS*))-; Cyclopent(b)oxireno(c)pyridine, 7-ethylidene-1a,2,3,7-tetrahydro-, (E)-(1aS,7aR)-; Virocidin; (1aR,7E,7aS)-7-Ethylidene-1a,2,3,7-tetrahydrocyclopent[b]oxireno[c]pyridine. Grade: ≥90%. CAS No. 31774-33-1. Molecular formula: C10H11NO. Mole weight: 161.20. | |
| Abil WE09 | Abil WE09 is a liquid nonionic W/O emulsifier that is distinguished by high emulsifying and emulsion-stabilizing action. The extremely favourable usage characteristics are achieved by the combination of a polyglycerol fatty acid ester with a silicone surfactant, the characteristic of which is the polymeric and polyfunctional structure. Synonyms: ABIL® WE 09; Polyglyceryl-4 Isostearate; Cetyl PEG/PPG-10/1 Dimethicone; Hexyl Laurate. | |
| Abil WE 09 | Abil WE 09. Grade: 95%. CAS No. 110734-66-2. | |
| Abiraterone | Abiraterone blocks the synthesis of androgens by inhibiting CYP17A1. It is used to treat metastatic, castration-resistant prostate cancer. Uses: The treatment of metastatic, castration-resistant prostate cancer. Synonyms: (3beta)-17-(3-pyridinyl)-androsta-5,16-dien-3-ol; 17-(3-Pyridyl)androsta-5,16-dien-3beta-ol; CB 7598; CB-7598; CB7598. Grade: >98%. CAS No. 154229-19-3. Molecular formula: C24H31NO. Mole weight: 349.51. | |
| Abiraterone acetate | The acetate form of abiraterone, which blocks the synthesis of androgens by inhibiting CYP17A1. It can be used to treat metastatic, castration-resistant prostate cancer. Uses: The treatment of metastatic, castration-resistant prostate cancer. Synonyms: CB7630; Zytiga; CB-7630; CB7630; Abiraterone (acetate). Grade: >98%. CAS No. 154229-18-2. Molecular formula: C26H33NO2. Mole weight: 391.55. | |
| Abiraterone Acetate-5,6-Epoxide | Abiraterone Acetate-5,6-Epoxide is an impurity of Abiraterone acetate. Abiraterone acetate is a CYP17A1 inhibitor and by extension androgen synthesis inhibitor. Synonyms: (3S,4aR,5aS,6aS,6bS,9aS,11aS,11bR)-9a,11b-dimethyl-9-(pyridin-3-yl)-1,2,3,4,5a,6,6a,6b,7,9a,10,11,11a,11b-tetradecahydrocyclopenta[1,2]phenanthro[8a,9-b]oxiren-3-yl acetate; (3β,5α,6α)-5,6-epoxy-17-(3-pyridinyl)-3-androst-16-en-3-ol-3-acetate. CAS No. 1868064-50-9. Molecular formula: C26H33NO3. Mole weight: 407.55. | |
| Abiraterone Acetate-[d4] | Abiraterone Acetate-[d4] is a labelled form of Abiraterone Acetate, the acetate form of abiraterone, which blocks the synthesis of androgens by inhibiting CYP17A1. This compound is also useful in kinetic isotope effect studies as well as for use as an internal standard in NMR experiments. Synonyms: (3S,8R,9S,10R,13S,14S)-10,13-Dimethyl-17-(pyridin-3-yl-d4)-2,3,4,7,8,9,10,11,12,13,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl acetate; Abiraterone Acetate D4; Androsta-5,16-dien-3-ol, 17-(3-pyridinyl-2,4,5,6-d4)-, 3-acetate, (3β)-; Abiraterone Acetate-d4; (3β)-17-(3-pyridinyl-d4)-androsta-5,16-dien-3-ol, acetate ester. Grade: >95%; ≥99% atom D. CAS No. 2122245-63-8. Molecular formula: C26H29D4NO2. Mole weight: 395.58. | |
| Abiraterone Acetate N-Oxide | Abiraterone Acetate N-Oxide is an impurity of Abiraterone acetate. Abiraterone acetate is a CYP17A1 inhibitor and by extension androgen synthesis inhibitor. Synonyms: 3-((3S,8R,9S,10R,13S,14S)-3-acetoxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl)pyridine 1-oxide. CAS No. 2517964-85-9. Molecular formula: C26H33NO3. Mole weight: 407.55. | |
| Abiraterone-[d4] | Abiraterone-[d4] is a labelled Abiraterone. Abiraterone is a steroidal CYP17A1 inhibitor with a therapeutic effect on androgen-dependent prostate cancer. Synonyms: (3β)-17-(3-Pyridinyl)androsta-5,16-dien-3-ol-d4; CB 7598-d4. Grade: > 95%. CAS No. 2122245-62-7. Molecular formula: C24H27NOD4. Mole weight: 353.54. | |
| Abiraterone Ethyl Ether | Abiraterone Ethyl Ether is an impurity of Abiraterone acetate. Abiraterone acetate is a CYP17A1 inhibitor and by extension androgen synthesis inhibitor. Synonyms: 3-((3S,8R,9S,10R,13S,14S)-3-ethoxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl)pyridine. CAS No. 2484719-14-2. Molecular formula: C26H35NO. Mole weight: 377.56. | |
| Abiraterone Ethyl Ether-[d5] | Abiraterone Ethyl Ether-[d5] is the labelled impurity of Abiraterone. Abiraterone blocks the synthesis of androgens by inhibiting CYP17A1. It is used to treat metastatic, castration-resistant prostate cancer. Synonyms: 3-((3S,8R,9S,10R,13S,14S)-3-ethoxy-d5-10,13-Dimethyl-2,3,4,7,8,9,10,11,12,13,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl)pyridine. Grade: > 98%. Molecular formula: C26H30D5NO. Mole weight: 382.59. | |
| Abiraterone isopropyl ether | An impurity of Abiraterone. Abiraterone acetate is a CYP17A1 inhibitor and by extension androgen synthesis inhibitor. In combination with prednisone, it is indicated for the treatment of patients with metastatic castration-resistant prostate cancer who have already received prior chemotherapy containing docetaxel under the trade name Zytiga. Synonyms: 3-[3-(1-Methylethoxy)androsta-5,16-dien-17-yl]pyridine; 3-((3S,8R,9S,10R,13S,14S)-3-Isopropoxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl)pyridine. Grade: ≥95%. CAS No. 2484719-15-3. Molecular formula: C27H37NO. Mole weight: 391.59. | |
| Abiraterone Isopropyl Ether-[d7] | Abiraterone Isopropyl Ether-[d7] is the labelled impurity of Abiraterone. Abiraterone blocks the synthesis of androgens by inhibiting CYP17A1. It is used to treat metastatic, castration-resistant prostate cancer. Synonyms: 3-((3S,8R,9S,10R,13S,14S)-3-Isopropoxy-d7-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl)pyridine. Grade: > 98%. Molecular formula: C27H30D7NO. Mole weight: 398.64. | |
| Abiraterone Methyl Ether | An impurity of Abiraterone. Abiraterone acetate is a CYP17A1 inhibitor and by extension androgen synthesis inhibitor. In combination with prednisone, it is indicated for the treatment of patients with metastatic castration-resistant prostate cancer who have already received prior chemotherapy containing docetaxel under the trade name Zytiga. Synonyms: 3-[(3β)-3-Methoxyandrosta-5,16-dien-17-yl]pyridine; 3-((3S,8R,9S,10R,13S,14S)-3-Methoxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl)pyridine. Grade: ≥95%. CAS No. 1470276-23-3. Molecular formula: C25H33NO. Mole weight: 363.55. | |
| Abiraterone O-β-D-glucuronide | An impurity of Abiraterone. Abiraterone acetate is a CYP17A1 inhibitor and by extension androgen synthesis inhibitor. In combination with prednisone, it is indicated for the treatment of patients with metastatic castration-resistant prostate cancer who have already received prior chemotherapy containing docetaxel under the trade name Zytiga. Synonyms: Abiraterone O-beta-D-glucuronide; (3β)-17-(3-Pyridinyl)androsta-5,16-dien-3-ol β-D-Glucuronide. CAS No. 2307194-33-6. Molecular formula: C30H39NO7. Mole weight: 525.63. | |
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