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1,4-dihydroxy-2-naphthoate polyprenyltransferase
This enzyme catalyses a step in the synthesis of menaquinone, in which the prenyl chain synthesized by polyprenyl diphosphate synthase is transferred to 1,4-dihydroxy-2-naphthoate (DHNA). The bacterial enzyme is an inner membrane protein, with the C-terminus located in the periplasm. It is highly specific for DHNA but not for a specific length of the prenyl chain. Group: Enzymes. Enzyme Commission Number: EC 2.5.1.74. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2812; 1,4-dihydroxy-2-naphthoate polyprenyltransferase; EC 2.5.1.74. Cat No: EXWM-2812.
1,4-dihydroxy-2-naphthoyl-CoA hydrolase
This enzyme participates in the synthesis of menaquinones, phylloquinone, as well as several plant pigments. The enzyme from the cyanobacterium Synechocystis sp. PCC 6803 does not accept benzoyl-CoA or phenylacetyl-CoA as substrates. Group: Enzymes. Synonyms: menI (gene name); ydiL (gene name). Enzyme Commission Number: EC 3.1.2.28. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3561; 1,4-dihydroxy-2-naphthoyl-CoA hydrolase; EC 3.1.2.28; menI (gene name); ydiL (gene name). Cat No: EXWM-3561.
1,4-dihydroxy-2-naphthoyl-CoA synthase
This enzyme is involved in the synthesis of 1,4-dihydroxy-2-naphthoate, a branch point metabolite leading to the biosynthesis of menaquinone (vitamin K2, in bacteria), phylloquinone (vitamin K1 in plants), and many plant pigments.The coenzyme A group is subsequently removed from the product by EC 3.1.2.28, 1,4-dihydroxy-2-naphthoyl-CoA hydrolase. Group: Enzymes. Synonyms: naphthoate synthase; 1,4-dihydroxy-2-naphthoate synthase; dihydroxynaphthoate synthase; o-succinylbenzoyl-CoA 1,4-dihydroxy-2-naphthoate-lyase (cyclizing); MenB; o-succinylbenzoyl-CoA dehydratase (cyclizing). Enzyme Commission Number: EC 4.1.3.36. CAS No. 61328-42-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4913; 1,4-dihydroxy-2-naphthoyl-CoA synthase; EC 4.1.3.36; 61328-42-5; naphthoate synthase; 1,4-dihydroxy-2-naphthoate synthase; dihydroxynaphthoate synthase; o-succinylbenzoyl-CoA 1,4-dihydroxy-2-naphthoate-lyase (cyclizing); MenB; o-succinylbenzoyl-CoA dehydratase (cyclizing). Cat No: EXWM-4913.
1,4-lactonase
The enzyme is specific for 1,4-lactones with 4-8 carbon atoms. It does not hydrolyse simple aliphatic esters, acetylcholine, sugar lactones or substituted aliphatic lactones, e.g. 3-hydroxy-4-butyrolactone; requires Ca2+. Group: Enzymes. Synonyms: γ-lactonase. Enzyme Commission Number: EC 3.1.1.25. CAS No. 37278-38-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3450; 1,4-lactonase; EC 3.1.1.25; 37278-38-9; γ-lactonase. Cat No: EXWM-3450.
Catalyses the two-electron reduction of biliverdin IXα at the C15 methine bridge. It has been proposed that this enzyme and EC 1.3.7.3, phycoerythrobilin:ferredoxin oxidoreductase, function as a dual enzyme complex in the conversion of biliverdin IXα into phycoerythrobilin. Group: Enzymes. Synonyms: PebA. Enzyme Commission Number: EC 1.3.7.2. CAS No. 347401-20-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1397; 15,16-dihydrobiliverdin:ferredoxin oxidoreductase; EC 1.3.7.2; 347401-20-1; PebA. Cat No: EXWM-1397.
1,5-anhydro-D-fructose dehydratase
This enzyme catalyses one of the steps in the anhydrofructose pathway, which leads to the degradation of glycogen and starch via 1,5-anhydro-D-fructose. The other enzymes involved in this pathway are EC 4.2.1.110 (aldos-2-ulose dehydratase), EC 4.2.2.13 [exo-(1?4)-α-D-glucan lyase] and EC 5.3.2.7 (ascopyrone tautomerase). Requires divalent (Ca2+ or Mg2+) or monovalent cations (Na+) for optimal activity. Unlike EC 4.2.1.110, the enzyme is specific for 1,5-anhydro-D-fructose as substrate and shows no activity towards aldose-2-uloses such as 2-dehydroglucose. In addition, it is inhibited by its end-product ascopyrone M and it cannot convert ascopyrone M into microthecin, as can EC 4.2.1.110. Group: Enzymes. Synonyms: 1,5-anhydro-D-fructose 4-dehydratase; 1,5-anhydro-D-fructose hydrolyase; 1,5-anhydro-D-arabino-hex-2-ulose dehydratase; AFDH; AF dehydratase; 1,5-anhydro-D-fructose hydro-lyase. Enzyme Commission Number: EC 4.2.1.111. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4951; 1,5-anhydro-D-fructose dehydratase; EC 4.2.1.111; 1,5-anhydro-D-fructose 4-dehydratase; 1,5-anhydro-D-fructose hydrolyase; 1,5-anhydro-D-arabino-hex-2-ulose dehydratase; AFDH; AF dehydratase; 1,5-anhydro-D-fructose hydro-lyase. Cat No: EXWM-4951.
1,5-anhydro-D-fructose reductase
Also reduces pyridine-3-aldehyde and 2,3-butanedione. Acetaldehyde, 2-dehydroglucose (glucosone) and glucuronate are poor substrates, but there is no detectable action on glucose, mannose and fructose. Group: Enzymes. Enzyme Commission Number: EC 1.1.1.263. CAS No. 206138-19-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0169; 1,5-anhydro-D-fructose reductase; EC 1.1.1.263; 206138-19-4. Cat No: EXWM-0169.
This enzyme is present in some but not all Rhizobium species and belongs in the GFO/IDH/MocA protein family. This enzyme differs from hepatic 1,5-anhydro-D-fructose reductase, which yields 1,5-anhydro-D-glucitol as the product (see EC 1.1.1.263). In Sinorhizobium morelense, the product of the reaction, 1,5-anhydro-D-mannitol, can be further metabolized to D-mannose. The enzyme also reduces 1,5-anhydro-D-erythro-hexo-2,3-diulose and 2-ketoaldoses (called osones), such as D-glucosone (D-arabino-hexos-2-ulose) and 6-deoxy-D-glucosone. It does not reduce common aldoses and ketoses, or non-sugar aldehydes and ketones. Group: Enzymes. Synonyms: 1,5-anhydro-D-fructose reductase (ambiguous); AFR. Enzyme Commission Number: EC 1.1.1.292. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0201; 1,5-anhydro-D-fructose reductase (1,5-anhydro-D-mannitol-forming); EC 1.1.1.292; 1,5-anhydro-D-fructose reductase (ambiguous); AFR. Cat No: EXWM-0201.
15-cis-phytoene desaturase
This enzyme is involved in carotenoid biosynthesis in plants and cyanobacteria. The enzyme from Synechococcus can also use NAD+ and NADP+ as electron acceptor under anaerobic conditions. The enzyme from Gentiana lutea shows no activity with NAD+ or NADP+. Group: Enzymes. Synonyms: phytoene desaturase (ambiguous); PDS; plant-type phytoene desaturase. Enzyme Commission Number: EC 1.3.5.5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1389; 15-cis-phytoene desaturase; EC 1.3.5.5; phytoene desaturase (ambiguous); PDS; plant-type phytoene desaturase. Cat No: EXWM-1389.
15-cis-phytoene synthase
Requires Mn2+ for activity. The enzyme produces 15-cis-phytoene. cf. EC 2.5.1.99, 15-trans-phytoene synthase. Group: Enzymes. Synonyms: prephytoene-diphosphate synthase (ambiguous); phytoene synthetase (ambiguous); PSase (ambiguous); geranylgeranyl-diphosphate geranylgeranyltransferase (ambiguous). Enzyme Commission Number: EC 2.5.1.32. CAS No. 50936-61-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2770; 15-cis-phytoene synthase; EC 2.5.1.32; 50936-61-3; prephytoene-diphosphate synthase (ambiguous); phytoene synthetase (ambiguous); PSase (ambiguous); geranylgeranyl-diphosphate geranylgeranyltransferase (ambiguous). Cat No: EXWM-2770.
15-hydroxyicosatetraenoate dehydrogenase
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (15S)-15-hydroxy-5,8,11-cis-13-trans-icosatetraenoate:NAD(P)+ 15-oxidoreductase. This enzyme is also called 15-hydroxyeicosatetraenoate dehydrogenase. This enzyme participates in arachidonic acid metabolism. Group: Enzymes. Synonyms: 15-hydroxyeicosatetraenoate dehydrogenase. Enzyme Commission Number: EC 1.1.1.232. CAS No. 117910-46-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0139; 15-hydroxyicosatetraenoate dehydrogenase; EC 1.1.1.232; 117910-46-0; 15-hydroxyeicosatetraenoate dehydrogenase. Cat No: EXWM-0139.
15-hydroxyprostaglandin-D dehydrogenase (NADP+)
Specific for prostaglandins D [cf. EC 1.1.1.141 15-hydroxyprostaglandin dehydrogenase (NAD+) and EC 1.1.1.197 15-hydroxyprostaglandin dehydrogenase (NADP+)]. Group: Enzymes. Synonyms: prostaglandin-D 15-dehydrogenase (NADP); dehydrogenase, prostaglandin D2; NADP-PGD2 dehydrogenase; dehydrogenase, 15-hydroxyprostaglandin (nicotinamide adenine dinucleotide phosphate); 15-hydroxy PGD2 dehydrogenase; 15-hydroxyprostaglandin dehydrogenase (NADP); NADP-dependent 15-hydroxyprostaglandin dehydrogenase; prostaglandin. Enzyme Commission Number: EC 1.1.1.196. CAS No. 84399-95-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0099; 15-hydroxyprostaglandin-D dehydrogenase (NADP+); EC 1.1.1.196; 84399-95-1; prostaglandin-D 15-dehydrogenase (NADP); dehydrogenase, prostaglandin D2; NADP-PGD2 dehydrogenase; dehydrogenase, 15-hydroxyprostaglandin (nicotinamide adenine dinucleotide phosphate); 15-hydroxy PGD2 dehydrogenase; 15-hydroxyprostaglandin dehydrogenase (NADP); NADP-dependent 15-hydroxyprostaglandin dehydrogenase; prostaglandin D2 dehydrogenase; NADP-linked 15-hydroxyprostaglandin dehydrogenase; NADP-specific 15-hydroxyprostaglandin dehydrogenase; NADP-linked prostaglandin D2 dehydrogenase; 15-hydroxyprostaglandin-D dehydrogenase (NADP). Cat No: EXWM-0099.
15-hydroxyprostaglandin dehydrogenase (NAD+)
Acts on prostaglandin E2, F2α and B1, but not on prostaglandin D2. cf. EC 1.1.1.196 15-hydroxyprostaglandin-D dehydrogenase (NADP+) and EC 1.1.1.197 15-hydroxyprostaglandin dehydrogenase (NADP+). Group: Enzymes. Synonyms: NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (type I); PGDH; 11α,15-dihydroxy-9-oxoprost-13-enoate:NAD+ 15-oxidoreductase; 15-OH-PGDH; 15-hydroxyprostaglandin dehydrogenase; 15-hydroxyprostanoic dehydrogenase; NAD+-specific 15-hydroxyprostaglandin dehydrogenase; prostaglandin dehydrogenase; 15-hydroxyprostaglandin dehydrogenase (NAD+); (5Z,13E)-(15S)-11α,15-dihydroxy-9-oxoprost-13. Enzyme Commission Number: EC 1.1.1.141. CAS No. 9030-87-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0045; 15-hydroxyprostaglandin dehydrogenase (NAD+); EC 1.1.1.141; 9030-87-9; NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (type I); PGDH; 11α,15-dihydroxy-9-oxoprost-13-enoate:NAD+ 15-oxidoreductase; 15-OH-PGDH; 15-hydroxyprostaglandin dehydrogenase; 15-hydroxyprostanoic dehydrogenase; NAD+-specific 15-hydroxyprostaglandin dehydrogenase; prostaglandin dehydrogenase; 15-hydroxyprostaglandin dehydrogenase (NAD+); (5Z,13E)-(15S)-11α,15-dihydroxy-9-oxoprost-13-enoate:NAD+ 15-oxidoreductase. Cat No: EXWM-0045.
15-hydroxyprostaglandin dehydrogenase (NADP+)
Acts on prostaglandins E2, F2α and B1, but not on prostaglandin D2 [cf. EC 1.1.1.141 15-hydroxyprostaglandin dehydrogenase (NAD+) and EC 1.1.1.196 15-hydroxyprostaglandin-D dehydrogenase (NADP+)]. May be identical with EC 1.1.1.189 prostaglandin-E2 9-reductase. Group: Enzymes. Synonyms: NADP-dependent 15-hydroxyprostaglandin dehydrogenase; NADP-linked 15-hydroxyprostaglandin dehydrogenase; NADP-specific 15-hydroxyprostaglandin dehydrogenase; type II 15-hydroxyprostaglandin dehydrogenase; 15-hydroxyprostaglandin dehydrogenase (NADP). Enzyme Commission Number: EC 1.1.1.197. CAS No. 54989-39-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0100; 15-hydroxyprostaglandin dehydrogenase (NADP+); EC 1.1.1.197; 54989-39-8; NADP-dependent 15-hydroxyprostaglandin dehydrogenase; NADP-linked 15-hydroxyprostaglandin dehydrogenase; NADP-specific 15-hydroxyprostaglandin dehydrogenase; type II 15-hydroxyprostaglandin dehydrogenase; 15-hydroxyprostaglandin dehydrogenase (NADP). Cat No: EXWM-0100.
15-hydroxyprostaglandin-I dehydrogenase (NADP+)
Specific for prostaglandin I2. Group: Enzymes. Synonyms: prostacyclin dehydrogenase; PG I2 dehydrogenase; prostacyclin dehydrogenase; NADP-linked 15-hydroxyprostaglandin (prostacyclin) dehydrogenase; NADP+-dependent PGI2-specific 15-hydroxyprostaglandin dehydrogenase; 15-hydroxyprostaglandin-I dehydrogenase (NADP). Enzyme Commission Number: EC 1.1.1.231. CAS No. 79468-49-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0138; 15-hydroxyprostaglandin-I dehydrogenase (NADP+); EC 1.1.1.231; 79468-49-8; prostacyclin dehydrogenase; PG I2 dehydrogenase; prostacyclin dehydrogenase; NADP-linked 15-hydroxyprostaglandin (prostacyclin) dehydrogenase; NADP+-dependent PGI2-specific 15-hydroxyprostaglandin dehydrogenase; 15-hydroxyprostaglandin-I dehydrogenase (NADP). Cat No: EXWM-0138.
15K DNA Marker
15K DNA Marker. 15k dna marker is a premixed, ready-to-load molecular weight marker containing eight linear double-stranded dna fragments. the dna ladder is suitable for use as molecular weight standards for agarose gel electrophoresis. the dna ladder contains 500 bp -15.0 kb dna fragments. the 5.0kb band (100 ng/5 μl) has doubled intensity than other bands to serve as reference band. Group: Markers & Ladders. Storage: Store at -20 ?. Cat No: MK-2013.
15-Lipoxygenase-2 from human, Recombinant
Two types of 15-lipoxygenase (15-LO) have been discovered and characterized, both of which metabolize arachidonic acid (AA) to produce 15(S)-hydroxyeicosatetraenoic acid (15(S)-HETE). 15-LO-1 oxygenates AA at both C-15 and C-12, whereas 15-LO-2 exclusively oxygenates C-15 of AA. Human 15-LO-2 has a molecular mass of approximately 76 kDa and exhibits approximately 40% identity to the reticulocyte 15-LO-1. Expression of 15-LO-2 appears to be restricted to prostate, lung, skin, and cornea and may play a role in the normal development of these tissues. The protein levels and enzymatic activity of 15-LO-2 are both down-regulated in prostate cancer compared with normal and benign prostate tissues, implicating a possible protective role for 15-LO-2 against tumor formation. Group: Enzymes. Synonyms: Arachidonate 15-lipoxygenase type II; 15-lipoxygenase-2; 15-LO-2; 15-LOX-2; ALOX15B. Enzyme Commission Number: EC 1.13.11.33. Purity: > 95% estimated by SDS-PAGE. Lipoxygenase. Mole weight: 76 kDa. Activity: 234.15 U/ml. Stability: As supplied, 6 months from the QC date provided on the Certificate of Analysis, when stored properly. Storage: at -80°C. Form: PBS, pH 7.4, 1 mM DTT and 20% glycerol. Source: E. coli. Species: Human. Arachidonate 15-lipoxygenase type II; 15-lipoxygenase-2; 15-LO-2; 15-LOX-2; ALOX15B. Cat No: NATE-1248.
The enzyme is specific for (1→6)-linked mannobiose and has no activity towards any other linkages, or towards p-nitrophenyl-α-D-mannopyranoside or baker's yeast mannan. It is strongly inhibited by Mn2+ but does not require Ca2+ or any other metal cofactor for activity.
1,6-α-D-mannosidase
The enzyme is specific for (1?6)-linked mannobiose and has no activity towards any other linkages, or towards p-nitrophenyl-α-D-mannopyranoside or baker's yeast mannan. It is strongly inhibited by Mn2+ but does not require Ca2+ or any other metal cofactor for activity. Group: Enzymes. Enzyme Commission Number: EC 3.2.1.163. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3845; 1,6-α-D-mannosidase; EC 3.2.1.163. Cat No: EXWM-3845.
16α-hydroxyprogesterone dehydratase
16α-Hydroxypregnenolone is also a substrate. Group: Enzymes. Synonyms: hydroxyprogesterone dehydroxylase; 16α-hydroxyprogesterone dehydroxylase; 16α-dehydroxylase; 16α-hydroxyprogesterone hydro-lyase. Enzyme Commission Number: EC 4.2.1.98. CAS No. 89287-36-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5082; 16α-hydroxyprogesterone dehydratase; EC 4.2.1.98; 89287-36-5; hydroxyprogesterone dehydroxylase; 16α-hydroxyprogesterone dehydroxylase; 16α-dehydroxylase; 16α-hydroxyprogesterone hydro-lyase. Cat No: EXWM-5082.
16α-hydroxysteroid dehydrogenase
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. Group: Enzymes. Synonyms: 16α-hydroxy steroid dehydrogenase. Enzyme Commission Number: EC 1.1.1.147. CAS No. 37250-74-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0051; 16α-hydroxysteroid dehydrogenase; EC 1.1.1.147; 37250-74-1; 16α-hydroxy steroid dehydrogenase. Cat No: EXWM-0051.
1,6-α-L-fucosidase
The enzyme from Aspergillus niger does not act on 1,2-, 1,3-, or 1,4-L-fucosyl linkages.
1,6-α-L-fucosidase
The enzyme from Aspergillus niger does not act on 1,2-, 1,3-, or 1,4-L-fucosyl linkages. Group: Enzymes. Synonyms: α-L-fucosidase; 1,6-L-fucosyl-N-acetyl-D-glucosaminylglycopeptide fucohydrolase. Enzyme Commission Number: EC 3.2.1.127. CAS No. 102925-35-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3810; 1,6-α-L-fucosidase; EC 3.2.1.127; 102925-35-9; α-L-fucosidase; 1,6-L-fucosyl-N-acetyl-D-glucosaminylglycopeptide fucohydrolase. Cat No: EXWM-3810.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (1R,6R)-1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate:NAD+ oxidoreductase (decarboxylating). Other names in common use include 3,5-cyclohexadiene-1,2-diol-1-carboxylate dehydrogenase, 3,5-cyclohexadiene-1,2-diol-1-carboxylic acid dehydrogenase, dihydrodihydroxybenzoate dehydrogenase, DHBDH, cis-1,2-dihydroxycyclohexa-3,5-diene-1-carboxylate dehydrogenase, 2-hydro-1,2-dihydroxybenzoate dehydrogenase, cis-1,2-dihydroxycyclohexa-3,5-diene-1-carboxylate:NAD+, oxidoreductase, and dihyd.Commission Number: EC 1.3.1.25. CAS No. 60496-16-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1299; 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase; EC 1.3.1.25; 60496-16-4; 3,5-cyclohexadiene-1,2-diol-1-carboxylate dehydrogenase; 3,5-cyclohexadiene-1,2-diol-1-carboxylic acid dehydrogenase; dihydrodihydroxybenzoate dehydrogenase; DHBDH; cis-1,2-dihydroxycyclohexa-3,5-diene-1-carboxylate dehydrogenase; 2-hydro-1,2-dihydroxybenzoate dehydrogenase; cis-1,2-dihydroxycyclohexa-3,5-diene-1-carboxylate:NAD+ oxidoreductase; dihydrodihydroxybenzoate dehydrogenase; (1R.
16-hydroxysteroid epimerase
This enzyme belongs to the family of isomerases, specifically those racemases and epimerases acting on other compounds. Group: Enzymes. Enzyme Commission Number: EC 5.1.99.2. CAS No. 37318-40-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5434; 16-hydroxysteroid epimerase; EC 5.1.99.2; 37318-40-4. Cat No: EXWM-5434.
16S rRNA (adenine1408-N1)-methyltransferase
The enzyme provides a panaminoglycoside-resistant nature through interference with the binding of aminoglycosides toward the A site of 16S rRNA through N1-methylation at position adenine1408. Group: Enzymes. Synonyms: kanamycin-apramycin resistance methylase; 16S rRNA:m1A1408 methyltransferase; KamB; NpmA; 16S rRNA m1A1408 methyltransferase. Enzyme Commission Number: EC 2.1.1.180. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1779; 16S rRNA (adenine1408-N1)-methyltransferase; EC 2.1.1.180; kanamycin-apramycin resistance methylase; 16S rRNA:m1A1408 methyltransferase; KamB; NpmA; 16S rRNA m1A1408 methyltransferase. Cat No: EXWM-1779.
KsgA introduces the most highly conserved ribosomal RNA modification, the dimethylation of adenine1518 and adenine1519 in 16S rRNA. Strains lacking the methylase are resistant to kasugamycin. Group: Enzymes. Synonyms: S-adenosylmethionine-6-N',N'-adenosyl (rRNA) dimethyltransferase; KsgA; ksgA methyltransferase. Enzyme Commission Number: EC 2.1.1.182. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1781; 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase; EC 2.1.1.182; S-adenosylmethionine-6-N',N'-adenosyl (rRNA) dimethyltransferase; KsgA; ksgA methyltransferase. Cat No: EXWM-1781.
16S rRNA (cytidine1402-2'-O)-methyltransferase
RsmI catalyses the 2'-O-methylation of cytidine1402 and RsmH (EC 2.1.1.199) catalyses the N4-methylation of cytidine1402 in 16S rRNA. Both methylations are necessary for efficient translation initiation at the UUG and GUG codons. Group: Enzymes. Synonyms: RsmI; YraL. Enzyme Commission Number: EC 2.1.1.198. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1797; 16S rRNA (cytidine1402-2'-O)-methyltransferase; EC 2.1.1.198; RsmI; YraL. Cat No: EXWM-1797.
16S rRNA (cytidine1409-2'-O)-methyltransferase
The bifunctional enzyme from Mycobacterium tuberculosis 2'-O-methylates cytidine1409 in helix 44 of 16S rRNA and cytidine1920 in helix 69 of 23S rRNA (cf. EC 2.1.1.226, 23S rRNA (cytidine1920-2'-O)-methyltransferase). Group: Enzymes. Synonyms: TlyA (ambiguous). Enzyme Commission Number: EC 2.1.1.227. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1830; 16S rRNA (cytidine1409-2'-O)-methyltransferase; EC 2.1.1.227; TlyA (ambiguous). Cat No: EXWM-1830.
16S rRNA (cytosine1402-N4)-methyltransferase
RsmH catalyses the N4-methylation of cytosine1402 andRsmI (EC 2.1.1.198) catalyses the 2'-O-methylation of cytosine1402 in 16S rRNA. Both methylations are necessary for efficient translation initiation at the UUG and GUG codons. Group: Enzymes. Synonyms: RsmH; MraW. Enzyme Commission Number: EC 2.1.1.199. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1798; 16S rRNA (cytosine1402-N4)-methyltransferase; EC 2.1.1.199; RsmH; MraW. Cat No: EXWM-1798.
16S rRNA (cytosine1407-C5)-methyltransferase
The enzyme specifically methylates cytosine1407 at C5 in 16S rRNA. Group: Enzymes. Synonyms: RNA m5C methyltransferase YebU; RsmF; YebU. Enzyme Commission Number: EC 2.1.1.178. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1776; 16S rRNA (cytosine1407-C5)-methyltransferase; EC 2.1.1.178; RNA m5C methyltransferase YebU; RsmF; YebU. Cat No: EXWM-1776.
16S rRNA (cytosine967-C5)-methyltransferase
The enzyme specifically methylates cytosine967 at C5 in 16S rRNA. Group: Enzymes. Synonyms: rsmB (gene name); fmu (gene name); 16S rRNA m5C967 methyltransferase. Enzyme Commission Number: EC 2.1.1.176. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1774; 16S rRNA (cytosine967-C5)-methyltransferase; EC 2.1.1.176; rsmB (gene name); fmu (gene name); 16S rRNA m5C967 methyltransferase. Cat No: EXWM-1774.
16S rRNA (guanine1207-N2)-methyltransferase
The enzyme reacts well with 30S subunits reconstituted from 16S RNA transcripts and 30S proteins but is almost inactive with the corresponding free RNA. The enzyme specifically methylates guanine1207 at N2 in 16S rRNA. Group: Enzymes. Synonyms: m2G1207 methyltransferase. Enzyme Commission Number: EC 2.1.1.172. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1770; 16S rRNA (guanine1207-N2)-methyltransferase; EC 2.1.1.172; m2G1207 methyltransferase. Cat No: EXWM-1770.
16S rRNA (guanine1405-N7)-methyltransferase
The enzyme from the antibiotic-producing bacterium Micromonospora zionensis specifically methylates guanine1405 at N7 in 16S rRNA, thereby rendering the ribosome resistant to 4,6-disubstituted deoxystreptamine aminoglycosides, which include gentamicins and kanamycins. Group: Enzymes. Synonyms: methyltransferase Sgm; m7G1405 Mtase; Sgm Mtase; Sgm; sisomicin-gentamicin methyltransferase; sisomicin-gentamicin methylase; GrmA; RmtB; RmtC; ArmA. Enzyme Commission Number: EC 2.1.1.179. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1777; 16S rRNA (guanine1405-N7)-methyltransferase; EC 2.1.1.179; methyltransferase Sgm; m7G1405 Mtase; Sgm Mtase; Sgm; sisomicin-gentamicin methyltransferase; sisomicin-gentamicin methylase; GrmA; RmtB; RmtC; ArmA. Cat No: EXWM-1777.
16S rRNA (guanine1516-N2)-methyltransferase
The enzyme specifically methylates guanine1516 at N2 in 16S rRNA. Group: Enzymes. Synonyms: yhiQ (gene name); rsmJ (gene name); m2G1516 methyltransferase. Enzyme Commission Number: EC 2.1.1.242. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1845; 16S rRNA (guanine1516-N2)-methyltransferase; EC 2.1.1.242; yhiQ (gene name); rsmJ (gene name); m2G1516 methyltransferase. Cat No: EXWM-1845.
16S rRNA (guanine527-N7)-methyltransferase
The enzyme specifically methylates guanine527 at N7 in 16S rRNA. Group: Enzymes. Synonyms: ribosomal RNA small subunit methyltransferase G; 16S rRNA methyltransferase RsmG; GidB; rsmG (gene name). Enzyme Commission Number: EC 2.1.1.170. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1768; 16S rRNA (guanine527-N7)-methyltransferase; EC 2.1.1.170; ribosomal RNA small subunit methyltransferase G; 16S rRNA methyltransferase RsmG; GidB; rsmG (gene name). Cat No: EXWM-1768.
16S rRNA (guanine966-N2)-methyltransferase
The enzyme efficiently methylates guanine966 of the assembled 30S subunits in vitro. Protein-free 16S rRNA is not a substrate for RsmD. The enzyme specifically methylates guanine966 at N2 in 16S rRNA. Group: Enzymes. Synonyms: yhhF (gene name);rsmD (gene name); m2G966 methyltransferase. Enzyme Commission Number: EC 2.1.1.171. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1769; 16S rRNA (guanine966-N2)-methyltransferase; EC 2.1.1.171; yhhF (gene name);rsmD (gene name); m2G966 methyltransferase. Cat No: EXWM-1769.
16S rRNA pseudouridine516 synthase
The enzyme is specific for uridine516 in 16S rRNA. In vitro, the enzyme does not modify free 16S rRNA. The preferred substrate is a 5'-terminal fragment of 16S rRNA complexed with 30S ribosomal proteins. Group: Enzymes. Synonyms: 16S RNA pseudouridine516 synthase; 16S PsiI516 synthase; 16S RNA ψ516 synthase; RNA pseudouridine synthase RsuA; RsuA; 16S RNA pseudouridine 516 synthase. Enzyme Commission Number: EC 5.4.99.19. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5558; 16S rRNA pseudouridine516 synthase; EC 5.4.99.19; 16S RNA pseudouridine516 synthase; 16S PsiI516 synthase; 16S RNA ψ516 synthase; RNA pseudouridine synthase RsuA; RsuA; 16S RNA pseudouridine 516 synthase. Cat No: EXWM-5558.
16S rRNA (uracil1498-N3)-methyltransferase
The enzyme specifically methylates uracil1498 at N3 in 16S rRNA. Group: Enzymes. Synonyms: DUF558 protein; YggJ; RsmE; m3U1498 specific methyltransferase. Enzyme Commission Number: EC 2.1.1.193. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1793; 16S rRNA (uracil1498-N3)-methyltransferase; EC 2.1.1.193; DUF558 protein; YggJ; RsmE; m3U1498 specific methyltransferase. Cat No: EXWM-1793.
A microsomal cytochrome P-450 (heme-thiolate) protein that catalyses two independent reactions at the same active site - the 17-hydroxylation of pregnenolone and progesterone, which is part of glucocorticoid hormones biosynthesis (EC 1.14.14.19), and the conversion of the 17-hydroxylated products via a 17,20-lyase reaction to form androstenedione and 3β-hydroxyandrost-5-en-17-one, leading to sex hormone biosynthesis. The activity of this reaction is dependent on the allosteric interaction of the enzyme with cytochrome b5 without any transfer of electrons from the cytochrome. The enzymes from different organisms differ in their substrate specificity. While the enzyme.son do not accept the former, and the enzyme from guinea pig does not accept the latter. Group: Enzymes. Synonyms: C-17/C-20 lyase; 17α-hydroxyprogesterone acetaldehyde-lyase; CYP17; CYP17A1 (gene name); 17α-hydroxyprogesterone 17,20-lyase. Enzyme Commission Number: EC 1.14.14.32. CAS No. 62213-24-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0930; 17α-hydroxyprogesterone deacetylase; EC 1.14.14.32; 62213-24-5; C-17/C-20 lyase; 17α-hydroxyprogesterone acetaldehyde-lyase; CYP17; CYP17A1 (gene name); 17α-hydroxyprogesterone 17,20-lyase. Cat No: EXWM-0930.
17β-estradiol 17-dehydrogenase
The enzyme oxidizes or reduces the hydroxy/keto group on C17 of estrogens and androgens in mammals and regulates the biological potency of these steroids. The mammalian enzyme is bifunctional and also catalyses EC 1.1.1.270, 3β-hydroxysteroid 3-dehydrogenase. The enzyme also acts on (S)-20-hydroxypregn-4-en-3-one and related compounds, oxidizing the (S)-20-group, but unlike EC 1.1.1.149, 20α-hydroxysteroid dehydrogenase, it is Si-specific with respect to NAD(P)+. Group: Enzymes. Synonyms: 20α-hydroxysteroid dehydrogenase; 17β,20α-hydroxysteroid dehydrogenase; 17β-estradiol dehydrogenase; estradiol dehydrogenase; estrogen 17-oxidoreductase; 17β-HSD; HSD17B7. Enzyme Commission Number: EC 1.1.1.62. CAS No. 9028-61-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0348; 17β-estradiol 17-dehydrogenase; EC 1.1.1.62; 9028-61-9; 20α-hydroxysteroid dehydrogenase; 17β,20α-hydroxysteroid dehydrogenase; 17β-estradiol dehydrogenase; estradiol dehydrogenase; estrogen 17-oxidoreductase; 17β-HSD; HSD17B7. Cat No: EXWM-0348.