Creative Enzymes - Products
Enzyme manufacturing for life science research and medicines, food, alcohol, fabric, paper etc. Uses include: drug discovery, cancer and infectious disease research, microbiology and personalized medicine.
| Product | Description | |
|---|---|---|
| 2,3',4,6-tetrahydroxybenzophenone synthase | Involved in the biosynthesis of plant xanthones. Benzoyl-CoA can replace 3-hydroxybenzoyl-CoA (cf. EC 2.3.1.220, 2,4,6-trihydroxybenzophenone synthase). Group: Enzymes. Synonyms: benzophenone synthase (ambiguous); BPS (ambiguous). Enzyme Commission Number: EC 2.3.1.151. CAS No. 175780-21-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2091; 2,3',4,6-tetrahydroxybenzophenone synthase; EC 2.3.1.151; 175780-21-9; benzophenone synthase (ambiguous); BPS (ambiguous). Cat No: EXWM-2091. |  |
| 2-(3-amino-3-carboxypropyl)histidine synthase | A [4Fe-4S] enzyme that modifies a histidine residue of the translation elongation factor 2 (EF2) via a 3-amino-3-carboxypropyl radical. The enzyme is present in archae and eukaryotes but not in eubacteria. The relevant histidine of EF2 is His715 in mammals, His699 in yeast and His600 in Pyrococcus horikoshii. Part of diphthamide biosynthesis. Group: Enzymes. Synonyms: Dph2. Enzyme Commission Number: EC 2.5.1.108. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2724; 2-(3-amino-3-carboxypropyl)histidine synthase; EC 2.5.1.108; Dph2. Cat No: EXWM-2724. | |
| 2,3-bis-O-geranylgeranyl-sn-glycerol 1-phosphate reductase [NAD(P)H] | A flavoprotein (FAD). The enzyme from the archaeon Thermoplasma acidophilum is involved in the biosynthesis of membrane lipids. In vivo the reaction occurs in the reverse direction with the formation of 2,3-bis-O-phytanyl-sn-glycerol 1-phosphate. cf. EC 1.3.7.11, 2,3-bis-O-geranylgeranyl-sn-glycero-phospholipid reductase. Group: Enzymes. Synonyms: digeranylgeranylglycerophospholipid reductase; Ta0516m (gene name); DGGGPL reductase; 2,3-digeranylgeranylglycerophospholipid reductase. Enzyme Commission Number: EC 1.3.1.101. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1273; 2,3-bis-O-geranylgeranyl-sn-glycerol 1-phosphate reductase [NAD(P)H]; EC 1.3.1.101; digeranylgeranylglycerophospholipid reductase; Ta0516m (gene name); DGGGPL reductase; 2,3-digeranylgeranylglycerophospholipid reductase. Cat No: EXWM-1273. | |
| 2,3-bis-O-geranylgeranyl-sn-glycero-phospholipid reductase | A flavoprotein (FAD). The enzyme is involved in the biosynthesis of archaeal membrane lipids. It catalyses the reduction of all 8 double bonds in 2,3-bis-O-geranylgeranyl-sn-glycero-phospholipids and all 4 double bonds in 3-O-geranylgeranyl-sn-glycerol phospholipids with comparable activity. Unlike EC 1.3.1.101, 2,3-bis-O-geranylgeranyl-sn-glycerol 1-phosphate reductase [NAD(P)H], this enzyme shows no activity with NADPH, and requires a dedicated ferredoxin. Group: Enzymes. Synonyms: AF0464 (gene name); 2,3-bis-O-geranylgeranyl-sn-glycerol 1-phosphate reductase (donor). Enzyme Commission Number: EC 1.3.7.11. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1392; 2,3-bis-O-geranylgeranyl-sn-glycero-phospholipid reductase; EC 1.3.7.11; AF0464 (gene name); 2,3-bis-O-geranylgeranyl-sn-glycerol 1-phosphate reductase (donor). Cat No: EXWM-1392. | |
| 2,3-bisphosphoglycerate 3-phosphatase | This reaction is a shortcut in the Rapoport-Luebering shunt. It bypasses the reactions of EC 3.1.3.13/EC 5.4.2.12 [bisphosphoglycerate phosphatase/phosphoglycerate mutase (2,3-diphosphoglycerate-independent)] and directly forms 2-phospho-D-glycerate by removing the 3-phospho-group of 2,3-diphospho-D-glycerate. The MIPP1 protein also catalyses the reaction of EC 3.1.3.62 (multiple inositol-polyphosphate phosphatase). Group: Enzymes. Synonyms: MIPP1; 2,3-BPG 3-phosphatase. Enzyme Commission Number: EC 3.1.3.80. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3686; 2,3-bisphosphoglycerate 3-phosphatase; EC 3.1.3.80; MIPP1; 2,3-BPG 3-phosphatase. Cat No: EXWM-3686. | |
| 2',3'-cyclic-nucleotide 2'-phosphodiesterase | Also hydrolyses 3'-nucleoside monophosphates and bis-4-nitrophenyl phosphate, but not 3'-deoxynucleotides. Similar reactions are carried out by EC 3.1.27.3 (ribonuclease T1) and EC 3.1.27.5 (pancreatic ribonuclease). Group: Enzymes. Synonyms: ribonucleoside 2',3'-cyclic phosphate diesterase; 2',3 -cyclic AMP phosphodiesterase; 2',3'-cyclic nucleotidase; cyclic 2',3'-nucleotide 2'-phosphodiesterase; cyclic 2',3'-nucleotide phosphodiesterase; 2',3'-cyclic nucleoside monophosphate phosphodiesterase; 2',3'-cyclic AMP 2'-phosphohydrolase; cyclic phosphodiesterase:3'-nucleotidase; 2',3'-cyclic n. Enzyme Commission Number: EC 3.1.4.16. CAS No. 9037-18-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3715; 2',3'-cyclic-nucleotide 2'-phosphodiesterase; EC 3.1.4.16; 9037-18-7; ribonucleoside 2',3'-cyclic phosphate diesterase; 2',3 -cyclic AMP phosphodiesterase; 2',3'-cyclic nucleotidase; cyclic 2',3'-nucleotide 2'-phosphodiesterase; cyclic 2',3'-nucleotide phosphodiesterase; 2',3'-cyclic nucleoside monophosphate phosphodiesterase; 2',3'-cyclic AMP 2'-phosphohydrolase; cyclic phosphodiesterase:3'-nucleotidase; 2',3'-cyclic nucleotide phosphohydrolase; 2':3'-cyclic phosphodiesterase; 2':3'-cyclic nucleotide phosphodiesterase:3'-nucleotidase. Cat No: EXWM-3715. | |
| 2',3'-cyclic-nucleotide 3'-phosphodiesterase | The brain enzyme acts on 2',3'-cyclic AMP more rapidly than on the UMP or CMP derivatives. An enzyme from liver acts on 2',3'-cyclic CMP more rapidly than on the purine derivatives; it also hydrolyses the corresponding 3',5'-cyclic phosphates, but more slowly. This latter enzyme has been called cyclic-CMP phosphodiesterase. Group: Enzymes. Synonyms: cyclic-CMP phosphodiesterase; 2',3'-cyclic AMP phosphodiesterase; cyclic 2',3'-nucleotide 3'-phosphodiesterase; cyclic 2',3'-nucleotide phosphodiesterase; 2',3'-cyclic nucleoside monophosphate phosphodiesterase; 2',3'-cyclic nucleotide 3'-phosphohydrolase; CNPase; 2',3'-cyclic nucleotide phosphohydrolase; 2':3'-cyclic nucleotide 3'-phosphod. Enzyme Commission Number: EC 3.1.4.37. CAS No. 60098-35-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3720; 2',3'-cyclic-nucleotide 3'-phosphodiesterase; EC 3.1.4.37; 60098-35-3; cyclic-CMP phosphodiesterase; 2',3'-cyclic AMP phosphodiesterase; cyclic 2',3'-nucleotide 3'-phosphodiesterase; cyclic 2',3'-nucleotide phosphodiesterase; 2',3'-cyclic nucleoside monophosphate phosphodiesterase; 2',3'-cyclic nucleotide 3'-phosphohydrolase; CNPase; 2',3'-cyclic nucleotide phosphohydrolase; 2':3'-cyclic nucleotide 3'-phosphodiesterase; 2':3'-CNMP-3'-ase. Cat No: EXWM-3720. | |
| 2,3-diaminopropionate N-oxalyltransferase | This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. Group: Enzymes. Synonyms: oxalyldiaminopropionate synthase; ODAP synthase; oxalyl-CoA:L-α,β-diaminopropionic acid oxalyltransferase; oxalyldiaminopropionic synthase; oxalyl-CoA:L-2,3-diaminopropanoate 3-N-oxalyltransferase. Enzyme Commission Number: EC 2.3.1.58. CAS No. 62213-48-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2237; 2,3-diaminopropionate N-oxalyltransferase; EC 2.3.1.58; 62213-48-3; oxalyldiaminopropionate synthase; ODAP synthase; oxalyl-CoA:L-α,β-diaminopropionic acid oxalyltransferase; oxalyldiaminopropionic synthase; oxalyl-CoA:L-2,3-diaminopropanoate 3-N-oxalyltransferase. Cat No: EXWM-2237. | |
| 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase | This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 2,3-dihydro-2,3-dihydroxybenzoate:NAD+ oxidoreductase. This enzyme is also called 2,3-DHB dehydrogenase. This enzyme participates in biosynthesis of siderophore group nonribosomal. Group: Enzymes. Synonyms: 2,3-DHB dehydrogenase; 2,3-dihydro-2,3-dihydroxybenzoate:NAD+ oxidoreductase. Enzyme Commission Number: EC 1.3.1.28. CAS No. 37250-40-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1301; 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase; EC 1.3.1.28; 37250-40-1; 2,3-DHB dehydrogenase; 2,3-dihydro-2,3-dihydroxybenzoate:NAD+ oxidoreductase. Cat No: EXWM-1301. | |
| 2,3-dihydroxy-2,3-dihydro-p-cumate dehydrogenase | Involved in the p-cymene degradation pathway in Pseudomonas putida. Group: Enzymes. Enzyme Commission Number: EC 1.3.1.58. CAS No. 176591-33-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1328; 2,3-dihydroxy-2,3-dihydro-p-cumate dehydrogenase; EC 1.3.1.58; 176591-33-6. Cat No: EXWM-1328. | |
| 2,3-dihydroxybenzoate 2,3-dioxygenase | Also acts, more slowly, with 2,3-dihydroxy-4-methylbenzoate and 2,3-dihydroxy-4-isopropylbenzoate. Group: Enzymes. Synonyms: 2,3-dihydroxybenzoate 2,3-oxygenase; 2,3-dihydroxybenzoate:oxygen 2,3-oxidoreductase (decyclizing). Enzyme Commission Number: EC 1.13.11.28. CAS No. 56802-97-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0547; 2,3-dihydroxybenzoate 2,3-dioxygenase; EC 1.13.11.28; 56802-97-2; 2,3-dihydroxybenzoate 2,3-oxygenase; 2,3-dihydroxybenzoate:oxygen 2,3-oxidoreductase (decyclizing). Cat No: EXWM-0547. | |
| 2,3-dihydroxybenzoate 3,4-dioxygenase | This enzyme belongs to the family of oxidoreductases, specifically those acting on single donors with O2 as oxidant and incorporation of two atoms of oxygen into the substrate (oxygenases). The oxygen incorporated need not be derived from O2. The systematic name of this enzyme class is 2,3-dihydroxybenzoate:oxygen 3,4-oxidoreductase (decyclizing). Other names in common use include o-pyrocatechuate oxygenase, 2,3-dihydroxybenzoate 1,2-dioxygenase, 2,3-dihydroxybenzoic oxygenase, and 2,3-dihydroxybenzoate oxygenase. This enzyme participates in benzoate degradation via hydroxylation. Group: Enzymes. Synonyms: o-pyrocatechuate oxygenase; 2,3-dihydroxybenzoate 1,2-dioxygenase; 2,3-dihydroxybenzoic oxygenase; 2,3-dihydroxybenzoate oxygenase; 2,3-dihydroxybenzoate:oxygen 3,4-oxidoreductase (decyclizing). Enzyme Commission Number: EC 1.13.11.14. CAS No. 9032-31-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0533; 2,3-dihydroxybenzoate 3,4-dioxygenase; EC 1.13.11.14; 9032-31-9; o-pyrocatechuate oxygenase; 2,3-dihydroxybenzoate 1,2-dioxygenase; 2,3-dihydroxybenzoic oxygenase; 2,3-dihydroxybenzoate oxygenase; 2,3-dihydroxybenzoate:oxygen 3,4-oxidoreductase (decyclizing). Cat No: EXWM-0533. | |
| (2,3-dihydroxybenzoyl)adenylate synthase | This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing nucleotide groups (nucleotidyltransferases). The systematic name of this enzyme class is ATP:2,3-dihydroxybenzoate adenylyltransferase. This enzyme is also called 2,3-dihydroxybenzoate-AMP ligase. This enzyme participates in biosynthesis of siderophore group nonribosomal. Group: Enzymes. Synonyms: 2,3-dihydroxybenzoate-AMP ligase. Enzyme Commission Number: EC 2.7.7.58. CAS No. 122332-73-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3269; (2,3-dihydroxybenzoyl)adenylate synthase; EC 2.7.7.58; 122332-73-4; 2,3-dihydroxybenzoate-AMP ligase. Cat No: EXWM-3269. | |
| 2,3-dihydroxyindole 2,3-dioxygenase | This enzyme belongs to the family of oxidoreductases, specifically those acting on single donors with O2 as oxidant and incorporation of two atoms of oxygen into the substrate (oxygenases). The oxygen incorporated need not be derived from O2. The systematic name of this enzyme class is 2,3-dihydroxyindole:oxygen 2,3-oxidoreductase (decyclizing). This enzyme participates in tryptophan metabolism. Group: Enzymes. Synonyms: 2,3-dihydroxyindole:oxygen 2,3-oxidoreductase (decyclizing). Enzyme Commission Number: EC 1.13.11.23. CAS No. 37256-62-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0542; 2,3-dihydroxyindole 2,3-dioxygenase; EC 1.13.11.23; 37256-62-5; 2,3-dihydroxyindole:oxygen 2,3-oxidoreductase (decyclizing). Cat No: EXWM-0542. | |
| 2,3-diketo-5-methylthiopentyl-1-phosphate enolase | The enzyme participates in the methionine salvage pathway in Bacillus subtilis.In some species a single bifunctional enzyme, EC 3.1.3.77, acireductone synthase, catalyses both this reaction and EC 3.1.3.87, 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase. Group: Enzymes. Synonyms: DK-MTP-1-P enolase; MtnW; YkrW; RuBisCO-like protein; RLP. Enzyme Commission Number: EC 5.3.2.5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5485; 2,3-diketo-5-methylthiopentyl-1-phosphate enolase; EC 5.3.2.5; DK-MTP-1-P enolase; MtnW; YkrW; RuBisCO-like protein; RLP. Cat No: EXWM-5485. | |
| 2,3-Dimethoxy-5-methyl-p-benzoquinone | 2,3-Dimethoxy-5-methyl-p-benzoquinone is used in the synthesis of a variety of polyprenylated quinones. Applications: Used in the synthesis of a variety of polyprenylated quinones. Group: Coenzymes. Synonyms: Coenzyme Q0. CAS No. 605-94-7. Purity: ≥98%. Mole weight: 182.17. Appearance: Crystalline powder. Form: Solid. Coenzyme Q0; 2,3-Dimethoxy-5-methyl-p-benzoquinone; 605-94-7. Cat No: COEC-052. | |
| 2,3-dimethylmalate lyase | This enzyme belongs to the family of lyases, specifically the oxo-acid-lyases, which cleave carbon-carbon bonds. This enzyme participates in c5-branched dibasic acid metabolism. Group: Enzymes. Synonyms: 2,3-dimethylmalate pyruvate-lyase; (2R,3S)-2,3-dimethylmalate pyruvate-lyase. Enzyme Commission Number: EC 4.1.3.32. CAS No. 73562-28-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4910; 2,3-dimethylmalate lyase; EC 4.1.3.32; 73562-28-4; 2,3-dimethylmalate pyruvate-lyase; (2R,3S)-2,3-dimethylmalate pyruvate-lyase. Cat No: EXWM-4910. | |
| 2,3-Diphospho-D-glyceric acid penta(cyclohexylammonium) salt | D-Glycerate 2,3-diphosphate (DPG), cofactor of both phosphoglyceric acid mutase and hemoglobin, may be used as a reference compound in analysis of blood cell (erythrocyte) glycolysic cycle metabolites. 2,3-diphosphoglycerate (DPG) may be used as a reference in assays that measure DPG levels to indicate the health status of erythrocytes/red blood cells (RBC). Applications: Used as a reference compound in analysis of blood cell (erythrocyte) glycolysic cycle metabolites. Group: Coenzymes. Synonyms: D-Glycerate 2,3-diphosphate pentacyclohexylamine salt. CAS No. 62868-79-5. Purity: ≥95%. Mole weight: 761.91. Appearance: Powder. Form: Solid. D-Glycerate 2,3-diphosphate pentacyclohexylamine salt; 2,3-Diphospho-D-glyceric acid penta(cyclohexylammonium) salt; 62868-79-5. Cat No: COEC-080. | |
| 2,3-epoxybenzoyl-CoA dihydrolase | The enzyme is involved in the aerobic benzoyl-CoA catabolic pathway of the bacterium Azoarcus evansii. The enzyme converts 2,3-epoxy-2,3-dihydrobenzoyl-CoA to its oxepin form prior to the ring-opening and the formation of a dialdehyde intermediate. Group: Enzymes. Synonyms: 2,3-dihydro-2,3-dihydroxybenzoyl-CoA lyase/hydrolase (deformylating); BoxC; dihydrodiol transforming enzyme; benzoyl-CoA oxidation component C; 2,3-dihydro-2,3-dihydroxybenzoyl-CoA 3,4-didehydroadipyl-CoA semialdehyde-lyase (formate-forming); benzoyl-CoA-dihydrodiol lyase (incorrect); 2,3-dihydro-2,3-dihydroxybenzoyl-CoA 3,4-didehydroadipyl-CoA-semialdehyde-lyase (formate-forming). Enzyme Commission Number: EC 4.1.2.44. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4880; 2,3-epoxybenzoyl-CoA dihydrolase; EC 4.1.2.44; 2,3-dihydro-2,3-dihydroxybenzoyl-CoA lyase/hydrolase (deformylating); BoxC; dihydrodiol transforming enzyme; benzoyl-CoA oxidation component C; 2,3-dihydro-2,3-dihydroxybenzoyl-CoA 3,4-didehydroadipyl-CoA semialdehyde-lyase (formate-forming); benzoyl-CoA-dihydrodiol lyase (incorrect); 2,3-dihydro-2,3-dihydroxybenzoyl-CoA 3,4-didehydroadipyl-CoA-semialdehyde-lyase (formate-forming). Cat No: EXWM-4880. | |
| 23S rRNA (adenine1618-N6)-methyltransferase | The recombinant YbiN protein is able to methylate partially deproteinized 50 S ribosomal subunit, but neither the completely assembled 50 S subunits nor completely deproteinized 23 S rRNA. Group: Enzymes. Synonyms: rRNA large subunit methyltransferase F; YbiN protein; rlmF (gene name); m6A1618 methyltransferase. Enzyme Commission Number: EC 2.1.1.181. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1780; 23S rRNA (adenine1618-N6)-methyltransferase; EC 2.1.1.181; rRNA large subunit methyltransferase F; YbiN protein; rlmF (gene name); m6A1618 methyltransferase. Cat No: EXWM-1780. | |
| 23S rRNA (adenine2030-N6)-methyltransferase | The recombinant RlmJ protein is most active in methylating deproteinized 23S ribosomal subunit, and does not methylate the completely assembled 50S subunits. Group: Enzymes. Synonyms: YhiR protein; rlmJ (gene name); m6A2030 methyltransferase. Enzyme Commission Number: EC 2.1.1.266. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1871; 23S rRNA (adenine2030-N6)-methyltransferase; EC 2.1.1.266; YhiR protein; rlmJ (gene name); m6A2030 methyltransferase. Cat No: EXWM-1871. | |
| 23S rRNA (adenine2085-N6)-dimethyltransferase | ErmC is a methyltransferase that confers resistance to the macrolide-lincosamide-streptogramin B group of antibiotics by catalysing the methylation of 23S rRNA at adenine2085. Group: Enzymes. Synonyms: ErmC' methyltransferase; ermC methylase;ermC 23S rRNA methyltransferase; rRNA:m6A methyltransferase ErmC'; ErmC'; rRNA methyltransferase ErmC'. Enzyme Commission Number: EC 2.1.1.184. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1783; 23S rRNA (adenine2085-N6)-dimethyltransferase; EC 2.1.1.184; ErmC' methyltransferase; ermC methylase;ermC 23S rRNA methyltransferase; rRNA:m6A methyltransferase ErmC'; ErmC'; rRNA methyltransferase ErmC'. Cat No: EXWM-1783. | |
| 23S rRNA (adenine2503-C2)-methyltransferase | Contains an [4Fe-4S] cluster. This enzyme is a member of the 'AdoMet radical' (radical SAM) family. S-Adenosyl-L-methionine acts as both a radical generator and as the source of the appended methyl group. RlmN first transfers an CH2 group to a conserved cysteine (Cys355 in Escherichia coli), the generated radical from a second S-adenosyl-L-methionine then attacks the methyl group, exctracting a hydrogen. The formed radical forms a covalent intermediate with the adenine group of the tRNA. RlmN is an endogenous enzyme used by the cell to refine functions of the ribosome in protein synthesis. The enzyme methylates adenosine by a radical mechanism with CH2 from the S-adenosyl-L-methionine and retention of the hydrogen at C-2 of adenosine2503 of 23S rRNA. It will also methylate 8-methyladenosine2503 of 23S rRNA. cf. EC 2.1.1.224 [23S rRNA (adenine2503-C8)-methyltransferase]. Group: Enzymes. Synonyms: RlmN; YfgB; Cfr. Enzyme Commission Number: EC 2.1.1.192. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1792; 23S rRNA (adenine2503-C2)-methyltransferase; EC 2.1.1.192; RlmN; YfgB; Cfr. Cat No: EXWM-1792. | |
| 23S rRNA (adenine2503-C8)-methyltransferase | This enzyme is a member of the 'AdoMet radical' (radical SAM) family. S-Adenosyl-L-methionine acts as both a radical generator and as the source of the appended methyl group. It contains an [4Fe-S] cluster. Cfr is an plasmid-acquired methyltransferase that protects cells from the action of antibiotics. The enzyme methylates adenosine at position 2503 of 23S rRNA by a radical mechanism, transferring a CH2 group from S-adenosyl-L-methionine while retaining the hydrogen at the C-8 position of the adenine. Cfr first transfers an CH2 group to a conserved cysteine (Cys338 in Staphylococcus aureus), the generated radical from a second S-adenosyl-L-methionine then attacks the methyl group, exctracting a hydrogen. The formed radical forms a covalent intermediate with the adenine group of the tRNA. The enzyme will also methylate 2-methyladenine produced by the action of EC 2.1.1.192 [23S rRNA (adenine2503-C2)-methyltransferase]. Group: Enzymes. Synonyms: Cfr (gene name). Enzyme Commission Number: EC 2.1.1.224. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1827; 23S rRNA (adenine2503-C8)-methyltransferase; EC 2.1.1.224; Cfr (gene name). Cat No: EXWM-1827. | |
| 23S rRNA (adenosine1067-2'-O)-methyltransferase | The methylase that is responsible for autoimmunity in the thiostrepton producer Streptomyces azureus, renders ribosomes completely resistant to thiostrepton. Group: Enzymes. Synonyms: 23S rRNA A1067 2'-methyltransferase; thiostrepton-resistance methylase; nosiheptide-resistance methyltransferase. Enzyme Commission Number: EC 2.1.1.230. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1833; 23S rRNA (adenosine1067-2'-O)-methyltransferase; EC 2.1.1.230; 23S rRNA A1067 2'-methyltransferase; thiostrepton-resistance methylase; nosiheptide-resistance methyltransferase. Cat No: EXWM-1833. | |
| 23S rRNA (cytidine1920-2'-O)-methyltransferase | The bifunctional enzyme from Mycobacterium tuberculosis 2'-O-methylates cytidine1920 in helix 69 of 23S rRNA and cytidine1409 in helix 44 of 16S rRNA (cf. EC 2.1.1.227, 16S rRNA (cytidine1409-2'-O)-methyltransferase). These methylations result in increased susceptibility to the antibiotics capreomycin and viomycin. Group: Enzymes. Synonyms: TlyA (ambiguous). Enzyme Commission Number: EC 2.1.1.226. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1829; 23S rRNA (cytidine1920-2'-O)-methyltransferase; EC 2.1.1.226; TlyA (ambiguous). Cat No: EXWM-1829. | |
| 23S rRNA (cytidine2498-2'-O)-methyltransferase | 23S rRNA (cytidine2498-2'-O)-methyltransferase (EC 2.1.1.186, YgdE, rRNA large subunit methyltransferase M, RlmM) is an enzyme with systematic name S-adenosyl-L-methionine:23S rRNA (cytidine2498-2'-O-)-methyltransferase. Group: Enzymes. Synonyms: YgdE; rRNA large subunit methyltransferase M; RlmM. Enzyme Commission Number: EC 2.1.1.186. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1785; 23S rRNA (cytidine2498-2'-O)-methyltransferase; EC 2.1.1.186; YgdE; rRNA large subunit methyltransferase M; RlmM. Cat No: EXWM-1785. | |
| 23S rRNA (cytosine1962-C5)-methyltransferase | The enzyme specifically methylates cytosine1962 at C5 in 23S rRNA. Group: Enzymes. Synonyms: RlmI; rRNA large subunit methyltransferase I; YccW. Enzyme Commission Number: EC 2.1.1.191. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1791; 23S rRNA (cytosine1962-C5)-methyltransferase; EC 2.1.1.191; RlmI; rRNA large subunit methyltransferase I; YccW. Cat No: EXWM-1791. | |
| 23S rRNA (guanine1835-N2)-methyltransferase | The enzyme methylates 23S rRNA in vitro, assembled 50S subunits are not a substrate. The enzyme specifically methylates guanine1835 at N2 in 23S rRNA. Group: Enzymes. Synonyms: ygjO (gene name); rlmG (gene name); ribosomal RNA large subunit methyltransferase G. Enzyme Commission Number: EC 2.1.1.174. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1772; 23S rRNA (guanine1835-N2)-methyltransferase; EC 2.1.1.174; ygjO (gene name); rlmG (gene name); ribosomal RNA large subunit methyltransferase G. Cat No: EXWM-1772. | |
| 23S rRNA (guanine2069-N7)-methyltransferase | The enzyme specifically methylates guanine2069 at position N7 in 23S rRNA. In γ-proteobacteria the enzyme also catalyses EC 2.1.1.173, 23S rRNA (guanine2445-N2)-methyltransferase, while in β-proteobacteria the activities are carried out by separate proteins. The enzyme from the γ-proteobacterium Escherichia coli has RNA unwinding activity as well. Group: Enzymes. Synonyms: rlmK (gene name); 23S rRNA m7G2069 methyltransferase. Enzyme Commission Number: EC 2.1.1.264. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1869; 23S rRNA (guanine2069-N7)-methyltransferase; EC 2.1.1.264; rlmK (gene name); 23S rRNA m7G2069 methyltransferase. Cat No: EXWM-1869. | |
| 23S rRNA (guanine2445-N2)-methyltransferase | The enzyme methylates 23S rRNA in vitro, assembled 50S subunits are not a substrate. The enzyme specifically methylates guanine2445 at N2 in 23S rRNA. Group: Enzymes. Synonyms: ycbY (gene name); rlmL (gene name). Enzyme Commission Number: EC 2.1.1.173. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1771; 23S rRNA (guanine2445-N2)-methyltransferase; EC 2.1.1.173; ycbY (gene name); rlmL (gene name). Cat No: EXWM-1771. | |
| 23S rRNA (guanine2535-N1)-methyltransferase | Streptomyces viridochromogenes produces the antibiotic avilamycin A which binds to the 50S ribosomal subunit to inhibit protein synthesis. To protect itself from the antibiotic, Streptomyces viridochromogenes utilizes two methyltransferases, 23S rRNA (guanine2535-N1)-methyltransferase and EC 2.1.1.208 [23S rRNA (uridine2479-2-O)-methyltransferase], whose actions confer avilamycin resistance to the RNA. Group: Enzymes. Synonyms: AviRa. Enzyme Commission Number: EC 2.1.1.209. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1810; 23S rRNA (guanine2535-N1)-methyltransferase; EC 2.1.1.209; AviRa. Cat No: EXWM-1810. | |
| 23S rRNA (guanine745-N1)-methyltransferase | The enzyme specifically methylates guanine745 at N1 in 23S rRNA. Group: Enzymes. Synonyms: Rlma(I); Rlma1; 23S rRNA m1G745 methyltransferase; YebH; RlmAI methyltransferase; ribosomal RNA(m1G)-methylase (ambiguous); rRNA(m1G)methylase (ambiguous); RrmA (ambiguous); 23S rRNA:m1G745 methyltransferase. Enzyme Commission Number: EC 2.1.1.187. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1786; 23S rRNA (guanine745-N1)-methyltransferase; EC 2.1.1.187; Rlma(I); Rlma1; 23S rRNA m1G745 methyltransferase; YebH; RlmAI methyltransferase; ribosomal RNA(m1G)-methylase (ambiguous); rRNA(m1G)methylase (ambiguous); RrmA (ambiguous); 23S rRNA:m1G745 methyltransferase. Cat No: EXWM-1786. | |
| 23S rRNA (guanine748-N1)-methyltransferase | The enzyme specifically methylates guanine748 at N1 in 23S rRNA. The methyltransferase RlmAII confers resistance to the macrolide antibiotic tylosin in the drug-producing strain Streptomyces fradiae. Group: Enzymes. Synonyms: Rlma(II); Rlma2; 23S rRNA m1G748 methyltransferase; RlmaII; Rlma II; tylosin-resistance methyltransferase RlmA(II); TlrB; rRNA large subunit methyltransferase II. Enzyme Commission Number: EC 2.1.1.188. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1787; 23S rRNA (guanine748-N1)-methyltransferase; EC 2.1.1.188; Rlma(II); Rlma2; 23S rRNA m1G748 methyltransferase; RlmaII; Rlma II; tylosin-resistance methyltransferase RlmA(II); TlrB; rRNA large subunit methyltransferase II. Cat No: EXWM-1787. | |
| 23S rRNA (guanosine2251-2'-O)-methyltransferase | The enzyme catalyses the methylation of guanosine2251, a modification conserved in the peptidyltransferase domain of 23S rRNA. Group: Enzymes. Synonyms: rlmB (gene name); yifH (gene name). Enzyme Commission Number: EC 2.1.1.185. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1784; 23S rRNA (guanosine2251-2'-O)-methyltransferase; EC 2.1.1.185; rlmB (gene name); yifH (gene name). Cat No: EXWM-1784. | |
| 23S rRNA pseudouridine1911/1915/1917 synthase | Pseudouridine synthase RluD converts uridines at positions 1911, 1915, and 1917 of 23S rRNA to pseudouridines. These nucleotides are located in the functionally important helix-loop 69 of 23S rRNA. Group: Enzymes. Synonyms: RluD; pseudouridine synthase RluD. Enzyme Commission Number: EC 5.4.99.23. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5563; 23S rRNA pseudouridine1911/1915/1917 synthase; EC 5.4.99.23; RluD; pseudouridine synthase RluD. Cat No: EXWM-5563. | |
| 23S rRNA (pseudouridine1915-N3)-methyltransferase | YbeA does not methylate uridine at position 1915. Group: Enzymes. Synonyms: YbeA; RlmH; pseudouridine methyltransferase; m3ψ methyltransferase; ψ1915-specific methyltransferase; rRNA large subunit methyltransferase H. Enzyme Commission Number: EC 2.1.1.177. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1775; 23S rRNA (pseudouridine1915-N3)-methyltransferase; EC 2.1.1.177; YbeA; RlmH; pseudouridine methyltransferase; m3ψ methyltransferase; ψ1915-specific methyltransferase; rRNA large subunit methyltransferase H. Cat No: EXWM-1775. | |
| 23S rRNA pseudouridine2457 synthase | The enzyme modifies uridine2457 in a stem of 23S RNA in Escherichia coli. Group: Enzymes. Synonyms: RluE; YmfC. Enzyme Commission Number: EC 5.4.99.20. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5560; 23S rRNA pseudouridine2457 synthase; EC 5.4.99.20; RluE; YmfC. Cat No: EXWM-5560. | |
| 23S rRNA pseudouridine2604 synthase | The enzyme is not completely specific for uridine2604 and can, to a small extent, also react with uridine2605. Group: Enzymes. Synonyms: RluF; YjbC. Enzyme Commission Number: EC 5.4.99.21. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5561; 23S rRNA pseudouridine2604 synthase; EC 5.4.99.21; RluF; YjbC. Cat No: EXWM-5561. | |
| 23S rRNA pseudouridine2605 synthase | Pseudouridine synthase RluB converts uridine2605 of 23S rRNA to pseudouridine. Group: Enzymes. Synonyms: RluB; YciL. Enzyme Commission Number: EC 5.4.99.22. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5562; 23S rRNA pseudouridine2605 synthase; EC 5.4.99.22; RluB; YciL. Cat No: EXWM-5562. | |
| 23S rRNA pseudouridine746 synthase | RluA is the sole protein responsible for the in vivo formation of 23S RNA pseudouridine746. The dual-specificity enzyme also catalyses the formation of uridine32 in tRNA. cf. EC 5.4.99.28 (tRNA pseudouridine32 synthase). Group: Enzymes. Synonyms: RluA (ambiguous); 23S RNA PSI746 synthase; 23S rRNA pseudouridine synthase; pseudouridine synthase RluA (ambiguous). Enzyme Commission Number: EC 5.4.99.29. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5569; 23S rRNA pseudouridine746 synthase; EC 5.4.99.29; RluA (ambiguous); 23S RNA PSI746 synthase; 23S rRNA pseudouridine synthase; pseudouridine synthase RluA (ambiguous). Cat No: EXWM-5569. | |
| 23S rRNA pseudouridine955/2504/2580 synthase | The enzyme converts uridines at position 955, 2504 and 2580 of 23S rRNA to pseudouridines. Group: Enzymes. Synonyms: RluC; pseudouridine synthase RluC. Enzyme Commission Number: EC 5.4.99.24. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5564; 23S rRNA pseudouridine955/2504/2580 synthase; EC 5.4.99.24; RluC; pseudouridine synthase RluC. Cat No: EXWM-5564. | |
| 23S rRNA (uracil1939-C5)-methyltransferase | The enzyme specifically methylates uracil1939 at C5 in 23S rRNA. The enzyme contains an [4Fe-4S] cluster coordinated by four conserved cysteine residues. Group: Enzymes. Synonyms: RumA; RNA uridine methyltransferase A; YgcA. Enzyme Commission Number: EC 2.1.1.190. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1790; 23S rRNA (uracil1939-C5)-methyltransferase; EC 2.1.1.190; RumA; RNA uridine methyltransferase A; YgcA. Cat No: EXWM-1790. | |
| 23S rRNA (uracil747-C5)-methyltransferase | The enzyme specifically methylates uracil747 at C5 in 23S rRNA. Group: Enzymes. Synonyms: YbjF; RumB; RNA uridine methyltransferase B. Enzyme Commission Number: EC 2.1.1.189. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1788; 23S rRNA (uracil747-C5)-methyltransferase; EC 2.1.1.189; YbjF; RumB; RNA uridine methyltransferase B. Cat No: EXWM-1788. | |
| 23S rRNA (uridine2479-2'-O)-methyltransferase | Streptomyces viridochromogenes produces the antibiotic avilamycin A which binds to the 50S ribosomal subunit to inhibit protein synthesis. To protect itself from the antibiotic, Streptomyces viridochromogenes utilizes two methyltransferases, 23S rRNA (uridine2479-2'-O)-methyltransferase and EC 2.1.1.209 [23S rRNA (guanine2535-N1)-methyltransferase], whose actions confer avilamycin resistance to the RNA. Group: Enzymes. Synonyms: AviRb. Enzyme Commission Number: EC 2.1.1.208. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1809; 23S rRNA (uridine2479-2'-O)-methyltransferase; EC 2.1.1.208; AviRb. Cat No: EXWM-1809. | |
| 23S rRNA (uridine2552-2'-O)-methyltransferase | The enzyme catalyses the 2'-O-methylation of the universally conserved U2552 in the A loop of 23S rRNA. Group: Enzymes. Synonyms: Um(2552) 23S ribosomal RNA methyltransferase; heat shock protein RrmJ; RrmJ; FTSJ; Um2552 methyltransferase. Enzyme Commission Number: EC 2.1.1.166. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1763; 23S rRNA (uridine2552-2'-O)-methyltransferase; EC 2.1.1.166; Um(2552) 23S ribosomal RNA methyltransferase; heat shock protein RrmJ; RrmJ; FTSJ; Um2552 methyltransferase. Cat No: EXWM-1763. | |
| 2,4,6-trihydroxybenzophenone synthase | Involved in the biosynthesis of plant xanthones. The enzyme from the plant Hypericum androsaemum L can use 3-hydroxybenzoyl-CoA instead of benzoyl-CoA, but with lower activity (cf. EC 2.3.1.151, 2,3',4,6-tetrahydroxybenzophenone synthase). Group: Enzymes. Synonyms: benzophenone synthase (ambiguous); BPS (ambiguous). Enzyme Commission Number: EC 2.3.1.220. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2167; 2,4,6-trihydroxybenzophenone synthase; EC 2.3.1.220; benzophenone synthase (ambiguous); BPS (ambiguous). Cat No: EXWM-2167. | |
| 2,4,7-trihydroxy-1,4-benzoxazin-3-one-glucoside 7-O-methyltransferase | The enzyme is involved in the biosynthesis of the protective and allelophatic benzoxazinoid DIMBOA [(2R)-4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin] in some plants, most commonly from the family of Poaceae (grasses). Group: Enzymes. Synonyms: BX7 (gene name); OMT BX7. Enzyme Commission Number: EC 2.1.1.241. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1844; 2,4,7-trihydroxy-1,4-benzoxazin-3-one-glucoside 7-O-methyltransferase; EC 2.1.1.241; BX7 (gene name); OMT BX7. Cat No: EXWM-1844. | |
| 2,4-diaminopentanoate dehydrogenase | Also acts, more slowly, on 2,5-diaminohexanoate forming 2-amino-5-oxohexanoate, which then cyclizes non-enzymically to 1-pyrroline-2-methyl-5-carboxylate. Group: Enzymes. Synonyms: 2,4-diaminopentanoic acid C4 dehydrogenase. Enzyme Commission Number: EC 1.4.1.12. CAS No. 39346-26-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1445; 2,4-diaminopentanoate dehydrogenase; EC 1.4.1.12; 39346-26-4; 2,4-diaminopentanoic acid C4 dehydrogenase. Cat No: EXWM-1445. | |
| 2,4-dichlorobenzoyl-CoA reductase | The enzyme, characterized from Corynebacterium strains able to grow on 2,4-dichlorobenzoate, forms part of the 2,4-dichlorobenzoate degradation pathway. Group: Enzymes. Enzyme Commission Number: EC 1.21.1.2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1247; 2,4-dichlorobenzoyl-CoA reductase; EC 1.21.1.2. Cat No: EXWM-1247. | |
| 2,4-dichlorophenol 6-monooxygenase | A flavoprotein (FAD). Also acts, more slowly, on 4-chlorophenol and 4-chloro-2-methylphenol; NADH can act instead of NADPH, but more slowly. Group: Enzymes. Synonyms: 2,4-dichlorophenol hydroxylase; 2,4-dichlorophenol monooxygenase. Enzyme Commission Number: EC 1.14.13.20. CAS No. 82047-82-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0801; 2,4-dichlorophenol 6-monooxygenase; EC 1.14.13.20; 82047-82-3; 2,4-dichlorophenol hydroxylase; 2,4-dichlorophenol monooxygenase. Cat No: EXWM-0801. | |
| 2,4-dienoyl-CoA reductase (NADPH) | Best substrates for reduction contain a 2,4-diene structure with a chain-length of 8 or 10. Group: Enzymes. Synonyms: 4-enoyl-CoA reductase (NADPH2); 4-enoyl coenzyme A (reduced nicotinamide adenine dinucleotide phosphate) reductase; 4-enoyl-CoA reductase; 2,4-dienoyl-CoA reductase (NADPH2). Enzyme Commission Number: EC 1.3.1.34. CAS No. 82869-38-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1307; 2,4-dienoyl-CoA reductase (NADPH); EC 1.3.1.34; 82869-38-3; 4-enoyl-CoA reductase (NADPH2); 4-enoyl coenzyme A (reduced nicotinamide adenine dinucleotide phosphate) reductase; 4-enoyl-CoA reductase; 2,4-dienoyl-CoA reductase (NADPH2). Cat No: EXWM-1307. | |
| 2,4-dihydroxy-1,4-benzoxazin-3-one-glucoside dioxygenase | The enzyme is involved in the biosynthesis of protective and allelophatic benzoxazinoids in some plants, most commonly from the family of Poaceae (grasses). Group: Enzymes. Synonyms: BX6 (gene name); DIBOA-Glc dioxygenase. Enzyme Commission Number: EC 1.14.20.2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1018; 2,4-dihydroxy-1,4-benzoxazin-3-one-glucoside dioxygenase; EC 1.14.20.2; BX6 (gene name); DIBOA-Glc dioxygenase. Cat No: EXWM-1018. | |
| 2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one 2-D-glucosyltransferase | The enzyme is involved in the detoxification of the benzoxazinoids DIBOA (2,4-dihydroxy-2H-1,4-benzoxazin-3(4H)-one) and DIMBOA (2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one) which are stored as the respective non-toxic glucosides in the vacuoles in some plants, most commonly from the family of Poaceae (grasses). Benzoxazinoids are known to exhibit antimicrobial, antifeedant, and antiinsecticidal effects and are involved in the interaction of plants with other plants, insects, or microorganisms. Group: Enzymes. Synonyms: uridine diphosphoglucose-2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one 2-glucosyltransferase; BX8; BX9; benzoxazinoid glucosyltransferase; DIMBOA glucosyltransferase. Enzyme Commission Number: EC 2.4.1.202. CAS No. 122544-56-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2430; 2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one 2-D-glucosyltransferase; EC 2.4.1.202; 122544-56-3; uridine diphosphoglucose-2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one 2-glucosyltransferase; BX8; BX9; benzoxazinoid glucosyltransferase; DIMBOA glucosyltransferase. Cat No: EXWM-2430. | |
| 2,4'-dihydroxyacetophenone dioxygenase | This enzyme belongs to the family of oxidoreductases, specifically those acting on single donors with O2 as oxidant and incorporation of two atoms of oxygen into the substrate (oxygenases). The oxygen incorporated need not be derived from O2. The systematic name of this enzyme class is 2,4'-dihydroxyacetophenone oxidoreductase (C-C-bond-cleaving). This enzyme is also called (4-hydroxybenzoyl)methanol oxygenase. This enzyme participates in bisphenol a degradation. Group: Enzymes. Synonyms: (4-hydroxybenzoyl)methanol oxygenase. Enzyme Commission Number: EC 1.13.11.41. CAS No. 257617-97-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0561; 2,4'-dihydroxyacetophenone dioxygenase; EC 1.13.11.41; 257617-97-3; (4-hydroxybenzoyl)methanol oxygenase. Cat No: EXWM-0561. | |
| 2,4-dinitroanisole O-demethylase | The enzyme, characterized from the bacterium Nocardioides sp. JS1661, is involved in the degradation of 2,4-dinitroanisole. Unlike other known O-demethylases, such as EC 1.14.99.15, 4-methoxybenzoate monooxygenase (O-demethylating), or EC 1.14.11.32, codeine 3-O-demethylase, it does not require oxygen or electron donors, and produces methanol rather than formaldehyde. Group: Enzymes. Synonyms: 2,4-dinitroanisole ether hydrolase; dnhA (gene name); dnhB (gene name); DNAN demethylase. Enzyme Commission Number: EC 3.3.2.14. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3999; 2,4-dinitroanisole O-demethylase; EC 3.3.2.14; 2,4-dinitroanisole ether hydrolase; dnhA (gene name); dnhB (gene name); DNAN demethylase. Cat No: EXWM-3999. | |
| 2,4-dinitrotoluene dioxygenase | This enzyme, characterized from the bacterium Burkholderia sp. strain DNT, is a member of the naphthalene family of bacterial Rieske non-heme iron dioxygenases. It comprises a multicomponent system, containing a Rieske [2Fe-2S] ferredoxin, an NADH-dependent flavoprotein reductase (EC 1.18.1.3, ferredoxin-NAD+ reductase), and an α3β3 oxygenase. The enzyme forms a cis-dihydroxylated product that spontaneously rearranges to form a catechol with accompanying release of nitrite. It does not act on nitrobenzene. cf. EC 1.14.12.23, nitroarene dioxygenase. Group: Enzymes. Synonyms: dntA (gene name). Enzyme Commission Number: EC 1.14.12.24. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0691; 2,4-dinitrotoluene dioxygenase; EC 1.14.12.24; dntA (gene name). Cat No: EXWM-0691. | |
| 24-hydroxycholesterol 7α-hydroxylase | A P450 heme-thiolate protein that is found in liver microsomes and in ciliary non-pigmented epithelium. The enzyme is specific for (24S)-cholest-5-ene-3β,24-diol, which is formed mostly in the brain by EC 1.14.14.25, cholesterol 24-hydroxylase. The direct electron donor to the enzyme is EC 1.6.2.4, NADPH-hemoprotein reductase. Group: Enzymes. Synonyms: 24-hydroxycholesterol 7α-monooxygenase; CYP39A1; CYP39A1 oxysterol 7α-hydroxylase. Enzyme Commission Number: EC 1.14.14.26. CAS No. 288309-90-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0923; 24-hydroxycholesterol 7α-hydroxylase; EC 1.14.14.26; 288309-90-0; 24-hydroxycholesterol 7α-monooxygenase; CYP39A1; CYP39A1 oxysterol 7α-hydroxylase. Cat No: EXWM-0923. | |
| 24-methylenesterol C-methyltransferase | This is the second methylation step of plant sterol biosynthesis (cf EC 2.1.1.142, cycloartenol 24-C-methyltransferase). Group: Enzymes. Synonyms: SMT2; 24-methylenelophenol C-241-methyltransferase. Enzyme Commission Number: EC 2.1.1.143. CAS No. 67165-89-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1739; 24-methylenesterol C-methyltransferase; EC 2.1.1.143; 67165-89-3; SMT2; 24-methylenelophenol C-241-methyltransferase. Cat No: EXWM-1739. | |
| 25/26-hydroxycholesterol 7α-hydroxylase | A P-450 (heme-thiolate) protein. Unlike EC 1.14.14.26, 24-hydroxycholesterol 7α-monooxygenase, which is specific for its oxysterol substrate, this enzyme can also metabolize the oxysterols 24,25-epoxycholesterol, 22-hydroxycholesterol and 24-hydroxycholesterol, but to a lesser extent. The direct electron donor to the enzyme is EC 1.6.2.4, NADPH-hemoprotein reductase. Group: Enzymes. Synonyms: 25-hydroxycholesterol 7α-monooxygenase; CYP7B1; CYP7B1 oxysterol 7α-hydroxylase; 27-hydroxycholesterol 7-monooxygenase; 27-hydroxycholesterol 7α-hydroxylase; cholest-5-ene-3β,25-diol,NADPH:oxygen oxidoreductase (7α-hydroxylating); 25-hydroxycholesterol 7α-hydroxylase. Enzyme Commission Number: EC 1.14.14.29. CAS No. 149316-80-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0926; 25/26-hydroxycholesterol 7α-hydroxylase; EC 1.14.14.29; 149316-80-3; 25-hydroxycholesterol 7α-monooxygenase; CYP7B1; CYP7B1 oxysterol 7α-hydroxylase; 27-hydroxycholesterol 7-monooxygenase; 27-hydroxycholesterol 7α-hydroxylase; cholest-5-ene-3β,25-diol,NADPH:oxygen oxidoreductase (7α-hydroxylating); 25-hydroxycholesterol 7α-hydroxylase. Cat No: EXWM-0926. | |
| 25/26-hydroxycholesterol 7α-hydroxylase | A P-450 (heme-thiolate) protein. Unlike EC 1.14.14.26, 24-hydroxycholesterol 7α-monooxygenase, which is specific for its oxysterol substrate, this enzyme can also metabolize the oxysterols 24,25-epoxycholesterol, 22-hydroxycholesterol and 24-hydroxycholesterol, but to a lesser extent. The direct electron donor to the enzyme is EC 1.6.2.4, NADPH-hemoprotein reductase. | |
| 25-(C4) 25-OH cholesterol | 25-(C4) 25-OH cholesterol. Group: Others. Purity: >99%. Mole weight: 718.806. Stability: 6 Months. Storage: -20°C. Avanti Polar Lipids; lipid products; bioactive lipids; fluorescent lipids; singnal transduction; cell pathways; 25-(C4) 25-OH cholesterol; 25-[4-(Dipyrrometheneboron difluoride)butanoyl]-25-hydroxycholesterol. Cat No: FLBZ-210. | |
| 2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one isomerase/dehydratase | The enzyme participates in a folate biosynthesis pathway in Chlamydia. Group: Enzymes. Enzyme Commission Number: EC 4.2.1.160. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5001; 2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one isomerase/dehydratase; EC 4.2.1.160. Cat No: EXWM-5001. | |
| 2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase | The reaction proceeds in the opposite direction. A step in riboflavin biosynthesis, NADPH and NADH function equally well as reductant. Differs from EC 1.1.1.193 [5-amino-6-(5-phosphoribosylamino)uracil reductase] since it does not catalyse the reduction of 5-amino-6-ribosylaminopyrimidine-2,4(1H,3H)-dione 5'-phosphate. Group: Enzymes. Synonyms: 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate reductase; MjaRED; MJ0671 (gene name). Enzyme Commission Number: EC 1.1.1.302. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0213; 2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase; EC 1.1.1.302; 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate reductase; MjaRED; MJ0671 (gene name). Cat No: EXWM-0213. | |
| 2,5-diaminovalerate transaminase | A pyridoxal-phosphate protein. 2,5-Diaminoglutarate can act instead of diaminopentanoate. Group: Enzymes. Synonyms: diamino-acid transaminase; diamino acid aminotransferase. Enzyme Commission Number: EC 2.6.1.8. CAS No. 9030-39-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2920; 2,5-diaminovalerate transaminase; EC 2.6.1.8; 9030-39-1; diamino-acid transaminase; diamino acid aminotransferase. Cat No: EXWM-2920. | |
| 2,5-didehydrogluconate reductase (2-dehydro-D-gluconate-forming) | The enzyme is involved in the catabolism of 2,5-didehydrogluconate. cf. EC 1.1.1.346, 2,5-didehydrogluconate reductase (2-dehydro-L-gulonate-forming). Group: Enzymes. Synonyms: 2,5-diketo-D-gluconate reductase (ambiguous). Enzyme Commission Number: EC 1.1.1.274. CAS No. 95725-95-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0181; 2,5-didehydrogluconate reductase (2-dehydro-D-gluconate-forming); EC 1.1.1.274; 95725-95-4; 2,5-diketo-D-gluconate reductase (ambiguous). Cat No: EXWM-0181. | |
| 2,5-didehydrogluconate reductase (2-dehydro-L-gulonate-forming) | The enzyme is involved in ketogluconate metabolism, and catalyses the reaction in vivo in the reverse direction to that shown. It is used in the commercial microbial production of ascorbate. cf. EC 1.1.1.274, 2,5-didehydrogluconate reductase (2-dehydro-D-gluconate-forming). Group: Enzymes. Synonyms: 2,5-diketo-D-gluconate-reductase (ambiguous); YqhE reductase; dkgA (gene name); dkgB (gene name). Enzyme Commission Number: EC 1.1.1.346. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0261; 2,5-didehydrogluconate reductase (2-dehydro-L-gulonate-forming); EC 1.1.1.346; 2,5-diketo-D-gluconate-reductase (ambiguous); YqhE reductase; dkgA (gene name); dkgB (gene name). Cat No: EXWM-0261. | |
| 2,5-dihydroxypyridine 5,6-dioxygenase | Requires Fe2+. Group: Enzymes. Synonyms: 2,5-dihydroxypyridine oxygenase; pyridine-2,5-diol dioxygenase; NicX. Enzyme Commission Number: EC 1.13.11.9. CAS No. 9029-57-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0604; 2,5-dihydroxypyridine 5,6-dioxygenase; EC 1.13.11.9; 9029-57-6; 2,5-dihydroxypyridine oxygenase; pyridine-2,5-diol dioxygenase; NicX. Cat No: EXWM-0604. | |
| 2,5-diketocamphane 1,2-monooxygenase | A flavoprotein (FMN) which requires Fe2+. A Baeyer-Villiger monooxygenase isolated from camphor-grown strains of Pseudomonas putida and encoded on the cam plasmid. Involved in the degradation of (+)-camphor. Requires a dedicated NADH-FMN reductase [cf. EC 1.5.1.42, FMN reductase (NADH)]. Can accept several bicyclic ketones including (+)- and (-)-camphor and adamantanone.The product spontaneously converts to [(1R)-2,2,3-trimethyl-5-oxocyclopent-3-enyl]acetate. Group: Enzymes. Synonyms: 2,5-diketocamphane lactonizing enzyme; ketolactonase I (ambiguous); 2,5-diketocamphane 1,2-monooxygenase oxygenating component; 2,5-DKCMO; camP (gene name); camphor 1,2-monooxygenase; camphor ketolactonase I. Enzyme Commission Number: EC 1.14.13.162. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0762; 2,5-diketocamphane 1,2-monooxygenase; EC 1.14.13.162; 2,5-diketocamphane lactonizing enzyme; ketolactonase I (ambiguous); 2,5-diketocamphane 1,2-monooxygenase oxygenating component; 2,5-DKCMO; camP (gene name); camphor 1,2-monooxygenase; camphor ketolactonase I. Cat No: EXWM-0762. | |
| 2,5-dioxopiperazine hydrolase | Highly specific; does not hydrolyse other dioxopiperazines, glycylglycine, proteins or barbiturates. Group: Enzymes. Synonyms: cyclo(Gly-Gly) hydrolase; cyclo(glycylglycine) hydrolase. Enzyme Commission Number: EC 3.5.2.13. CAS No. 97599-45-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4496; 2,5-dioxopiperazine hydrolase; EC 3.5.2.13; 97599-45-6; cyclo(Gly-Gly) hydrolase; cyclo(glycylglycine) hydrolase. Cat No: EXWM-4496. | |
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