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2'''-acetyl-6'''-hydroxyneomycin C deacetylase
Involved in the biosynthetic pathway of aminoglycoside antibiotics of the neomycin family. The enzyme from the bacterium Streptomyces fradiae also catalyses EC 3.5.1.112, 2'-N-acetylparomamine deacetylase. Group: Enzymes. Synonyms: neoL (gene name). Enzyme Commission Number: EC 3.5.1.113. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4393; 2'''-acetyl-6'''-hydroxyneomycin C deacetylase; EC 3.5.1.113; neoL (gene name). Cat No: EXWM-4393.
2-acylglycerol-3-phosphate O-acyltransferase
Saturated acyl-CoA thioesters are the most effective acyl donors. Group: Enzymes. Synonyms: 2-acylglycerophosphate acyltransferase. Enzyme Commission Number: EC 2.3.1.52. CAS No. 51901-17-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2232; 2-acylglycerol-3-phosphate O-acyltransferase; EC 2.3.1.52; 51901-17-8; 2-acylglycerophosphate acyltransferase. Cat No: EXWM-2232.
2-acylglycerol O-acyltransferase
Various 2-acylglycerols can act as acceptor; palmitoyl-CoA and other long-chain acyl-CoAs can act as donors. The sn-1 position and the sn-3 position are both acylated, at about the same rate. Group: Enzymes. Synonyms: acylglycerol palmitoyltransferase; monoglyceride acyltransferase; acyl coenzyme A-monoglyceride acyltransferase; monoacylglycerol acyltransferase. Enzyme Commission Number: EC 2.3.1.22. CAS No. 9055-17-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2166; 2-acylglycerol O-acyltransferase; EC 2.3.1.22; 9055-17-8; acylglycerol palmitoyltransferase; monoglyceride acyltransferase; acyl coenzyme A-monoglyceride acyltransferase; monoacylglycerol acyltransferase. Cat No: EXWM-2166.
2-acylglycerophosphocholine O-acyltransferase
This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. This enzyme participates in glycerophospholipid metabolism. Group: Enzymes. Synonyms: 2-acylglycerol-3-phosphorylcholine acyltransferase; 2-acylglycerophosphocholine acyltransferase. Enzyme Commission Number: EC 2.3.1.62. CAS No. 64295-73-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2242; 2-acylglycerophosphocholine O-acyltransferase; EC 2.3.1.62; 64295-73-4; 2-acylglycerol-3-phosphorylcholine acyltransferase; 2-acylglycerophosphocholine acyltransferase. Cat No: EXWM-2242.
2-alkenal reductase (NADP+)
Shows highest activity with 1-nitrocyclohexene but also has significant activity with 2-methylpentenal and trans-cinnamaldehyde. Involved in the detoxication of α,β-unsaturated aldehydes and ketones. Has very low activity with NAD as reductant (cf. EC 1.3.1.74, 2-alkenal reductase [NAD(P)+]). Group: Enzymes. Synonyms: NADPH-dependent alkenal/one oxidoreductase; NADPH:2-alkenal α,β-hydrogenase. Enzyme Commission Number: EC 1.3.1.102. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1274; 2-alkenal reductase (NADP+); EC 1.3.1.102; NADPH-dependent alkenal/one oxidoreductase; NADPH:2-alkenal α,β-hydrogenase. Cat No: EXWM-1274.
2-alkenal reductase [NAD(P)+]
Highly specific for 4-hydroxynon-2-enal and non-2-enal. Alk-2-enals of shorter chain have lower affinities. Exhibits high activities also for alk-2-enones such as but-3-en-2-one and pent-3-en-2-one. Inactive with cyclohex-2-en-1-one and 12-oxophytodienoic acid. Involved in the detoxication of α,β-unsaturated aldehydes and ketones [cf. EC 1.3.1.102, 2-alkenal reductase (NADP+)]. Group: Enzymes. Synonyms: NAD(P)H-dependent alkenal/one oxidoreductase; NADPH:2-alkenal α,β-hydrogenase; 2-alkenal reductase. Enzyme Commission Number: EC 1.3.1.74. CAS No. 52227-95-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1343; 2-alkenal reductase [NAD(P)+]; EC 1.3.1.74; 52227-95-9; NAD(P)H-dependent alkenal/one oxidoreductase; NADPH:2-alkenal α,β-hydrogenase; 2-alkenal reductase. Cat No: EXWM-1343.
2-alkyn-1-ol dehydrogenase
Acts on a variety of 2-alkyn-1-ols, and also on 1,4-butanediol. NADP+ also acts as acceptor, but more slowly. Group: Enzymes. Enzyme Commission Number: EC 1.1.1.165. CAS No. 54576-94-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0068; 2-alkyn-1-ol dehydrogenase; EC 1.1.1.165; 54576-94-2. Cat No: EXWM-0068.
2α-hydroxytaxane 2-O-benzoyltransferase
The enzyme was studied using the semisynthetic substrate 2-debenzoyl-7,13-diacetylbaccatin III. It will not acylate the hydroxy group at 1β, 7β, 10β or 13α of 10-deacetyl baccatin III, or at 2α or 5α of taxa-4(20),11-diene-2α,5α-diol. Group: Enzymes. Synonyms: benzoyl-CoA:taxane 2α-O-benzoyltransferase. Enzyme Commission Number: EC 2.3.1.166. CAS No. 329318-50-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2106; 2α-hydroxytaxane 2-O-benzoyltransferase; EC 2.3.1.166; 329318-50-5; benzoyl-CoA:taxane 2α-O-benzoyltransferase. Cat No: EXWM-2106.
Requires Fe2+. The enzyme, characterized from a marine bacterium, is involved in a 2-aminoethylphosphonate degradation pathway. Group: Enzymes. Synonyms: phnZ (gene name). Enzyme Commission Number: EC 1.13.11.78. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0598; 2-amino-1-hydroxyethylphosphonate dioxygenase (glycine-forming); EC 1.13.11.78; phnZ (gene name). Cat No: EXWM-0598.
The enzyme plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids. The enzyme can also catalyse the reaction of EC 4.1.2.13, fructose-bisphosphate aldolase. Group: Enzymes. Synonyms: ADH synthase; ADHS; MJ0400 (gene name). Enzyme Commission Number: EC 2.2.1.10. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2026; 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase; EC 2.2.1.10; ADH synthase; ADHS; MJ0400 (gene name). Cat No: EXWM-2026.
Part of the pathway for the biosynthesis of grixazone, a mixture of yellow pigments produced by the bacterium Streptomyces griseus. Group: Enzymes. Synonyms: griI (gene name). Enzyme Commission Number: EC 4.1.2.56. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4893; 2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate synthase; EC 4.1.2.56; griI (gene name). Cat No: EXWM-4893.
2-amino-4-deoxychorismate dehydrogenase
The sequential action ofEC 2.6.1.86, 2-amino-4-deoxychorismate synthase and this enzyme leads to the formation of the benzoxazolinate moiety of the enediyne antitumour antibiotic C-1027. Group: Enzymes. Synonyms: ADIC dehydrogenase; 2-amino-2-deoxyisochorismate dehydrogenase; SgcG. Enzyme Commission Number: EC 1.3.99.24. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1426; 2-amino-4-deoxychorismate dehydrogenase; EC 1.3.99.24; ADIC dehydrogenase; 2-amino-2-deoxyisochorismate dehydrogenase; SgcG. Cat No: EXWM-1426.
2-amino-4-deoxychorismate synthase
Requires Mg2+. The reaction occurs in the reverse direction to that shown above. In contrast to most anthranilate-synthase I (ASI) homologues, this enzyme is not inhibited by tryptophan. In Streptomyces globisporus, the sequential action of this enzyme and EC 1.3.99.24, 2-amino-4-deoxychorismate dehydrogenase, leads to the formation of the benzoxazolinate moiety of the enediyne antitumour antibiotic C-1027.In certain Pseudomonads the enzyme participates in the biosynthesis of phenazine, a precursor for several compounds with antibiotic activity. Group: Enzymes. Synonyms: ADIC synthase; 2-amino-2-deoxyisochorismate synthase;SgcD. Enzyme Commission Number: EC 2.6.1.86. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2927; 2-amino-4-deoxychorismate synthase; EC 2.6.1.86; ADIC synthase; 2-amino-2-deoxyisochorismate synthase;SgcD. Cat No: EXWM-2927.
Binds 2 Mg2+ ions that are essential for activity. The enzyme participates in the biosynthetic pathways for folate (in bacteria, plants and fungi) and methanopterin (in archaea). The enzyme exists in varying types of multifunctional proteins in different organisms. The enzyme from the bacterium Streptococcus pneumoniae also harbours the activity of EC 4.1.2.25, dihydroneopterin aldolase, the enzyme from the plant Arabidopsis thaliana harbours the activity of EC 2.5.1.15, dihydropteroate synthase, while the enzyme from yeast Saccharomyces cerevisiae is trifunctional with both of the two above mentioned activities. Group: Enzymes. Synonyms: 2-amino-4-hydroxy-6-hydroxymethyldi. Enzyme Commission Number: EC 2.7.6.3. CAS No. 37278-23-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3222; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase; EC 2.7.6.3; 37278-23-2; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; H2-pteridine-CH2OH pyrophosphokinase; 7,8-dihydroxymethylpterin-pyrophosphokinase; HPPK; 7,8-dihydro-6-hydroxymethylpterin pyrophosphokinase; hydroxymethyldihydropteridine pyrophosphokinase; ATP:2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine 6'-diphosphotransferase. Cat No: EXWM-3222.
2-amino-5-chlorophenol 1,6-dioxygenase
The enzyme, a member of the nonheme-iron(II)-dependent dioxygenase family, is an extradiol-type dioxygenase that utilizes a non-heme ferrous iron to cleave the aromatic ring at the meta position (relative to the hydroxyl substituent). The enzyme from the bacterium Comamonas testosteroni CNB-1 also has the activity of EC 1.13.11.74, 2-aminophenol 1,6-dioxygenase. Group: Enzymes. Synonyms: cnbC (gene name); 2-amino-5-chlorophenol:oxygen 1,6-oxidoreductase (decyclizing). Enzyme Commission Number: EC 1.13.11.76. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0596; 2-amino-5-chlorophenol 1,6-dioxygenase; EC 1.13.11.76; cnbC (gene name); 2-amino-5-chlorophenol:oxygen 1,6-oxidoreductase (decyclizing). Cat No: EXWM-0596.
The enzyme catalyses the second step in archaeal riboflavin and 7,8-didemethyl-8-hydroxy-5-deazariboflavin biosynthesis. The first step is catalysed by EC 3.5.4.29 (GTP cyclohydrolase IIa). The bacterial enzyme, EC 3.5.4.25 (GTP cyclohydrolase II) catalyses both reactions. Group: Enzymes. Synonyms: ArfB. Enzyme Commission Number: EC 3.5.1.102. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4381; 2-amino-5-formylamino-6-ribosylaminopyrimidin-4(3H)-one 5'-monophosphate deformylase; EC 3.5.1.102; ArfB. Cat No: EXWM-4381.
A pyridoxal-phosphate protein. Group: Enzymes. Synonyms: α-aminoadipate aminotransferase; 2-aminoadipate aminotransferase; 2-aminoadipic aminotransferase; glutamic-ketoadipic transaminase; glutamate-α-ketoadipate transaminase. Enzyme Commission Number: EC 2.6.1.39. CAS No. 9033-00-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2879; 2-aminoadipate transaminase; EC 2.6.1.39; 9033-00-5; α-aminoadipate aminotransferase; 2-aminoadipate aminotransferase; 2-aminoadipic aminotransferase; glutamic-ketoadipic transaminase; glutamate-α-ketoadipate transaminase. Cat No: EXWM-2879.
2-aminobenzenesulfonate 2,3-dioxygenase
This enzyme belongs to the family of oxidoreductases, specifically those acting on paired donors, with O2 as oxidant and incorporation or reduction of oxygen. The oxygen incorporated need not be derived from O2 with NADH or NADPH as one donor, and incorporation of two atoms o oxygen into the other donor. The systematic name of this enzyme class is 2-aminobenzenesulfonate,NADH:oxygen oxidoreductase (2,3-hydroxylating, ammonia-forming). This enzyme is also called 2-aminosulfobenzene 2,3-dioxygenase. This enzyme participates in benzoate degradation via hydroxylation. Group: Enzymes. Synonyms: 2-aminosulfobenzene 2,3-dioxygenase. Enzyme Commission Number: EC 1.14.12.14. CAS No. 156621-16-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0683; 2-aminobenzenesulfonate 2,3-dioxygenase; EC 1.14.12.14; 156621-16-8; 2-aminosulfobenzene 2,3-dioxygenase. Cat No: EXWM-0683.
2-aminobenzoylacetyl-CoA thioesterase
The enzyme, characterized from the bacterium Pseudomonas aeruginosa, participates in the production of the signal molecule 2-heptyl-4(1H)-quinolone (HHQ). Group: Enzymes. Synonyms: pqsE (gene name). Enzyme Commission Number: EC 3.1.2.32. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3566; 2-aminobenzoylacetyl-CoA thioesterase; EC 3.1.2.32; pqsE (gene name). Cat No: EXWM-3566.
2-aminoethylphosphonate dioxygenase
Requires Fe2+ and ascorbate. The enzyme, characterized from an uncultured marine bacterium, is involved in a (2-aminoethyl)phosphonate degradation pathway. Group: Enzymes. Synonyms: phnY (gene name). Enzyme Commission Number: EC 1.14.11.46. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0665; 2-aminoethylphosphonate dioxygenase; EC 1.14.11.46; phnY (gene name). Cat No: EXWM-0665.
2-aminoethylphosphonate-pyruvate transaminase
A pyridoxal-phosphate protein. 2-Aminoethylarsonate can replace 2-aminoethylphosphonate as a substrate. Group: Enzymes. Synonyms: (2-aminoethyl)phosphonate transaminase; (2-aminoethyl)phosphonate aminotransferase; (2-aminoethyl)phosphonic acid aminotransferase; 2-aminoethylphosphonate-pyruvate aminotransferase; 2-aminoethylphosphonate aminotransferase; 2-aminoethylphosphonate transaminase; AEP transaminase; AEPT. Enzyme Commission Number: EC 2.6.1.37. CAS No. 37277-91-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2877; 2-aminoethylphosphonate-pyruvate transaminase; EC 2.6.1.37; 37277-91-1; (2-aminoethyl)phosphonate transaminase; (2-aminoethyl)phosphonate aminotransferase; (2-aminoethyl)phosphonic acid aminotransferase; 2-aminoethylphosphonate-pyruvate aminotransferase; 2-aminoethylphosphonate aminotransferase; 2-aminoethylphosphonate transaminase; AEP transaminase; AEPT. Cat No: EXWM-2877.
2-aminohexano-6-lactam racemase
Contains pyridoxal 5'-phosphate. Also racemises 2-aminopentano-5-lactam (α-amino-Δ-valerolactam) and 2-amino-4-thiahexano-6-lactam (where S replaces CH2 of C-4). It does not catalyse the racemisation of α-amino acids but has some transaminase activity with them. Group: Enzymes. Synonyms: α-amino-ε-caprolactam racemase. Enzyme Commission Number: EC 5.1.1.15. CAS No. 52652-64-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5373; 2-aminohexano-6-lactam racemase; EC 5.1.1.15; 52652-64-9; α-amino-ε-caprolactam racemase. Cat No: EXWM-5373.
2-aminohexanoate transaminase
A pyridoxal-phosphate protein. Also acts on L-leucine and, more slowly, on L-isoleucine, L-2-aminopentanoate and L-aspartate. Group: Enzymes. Synonyms: norleucine transaminase; norleucine (leucine) aminotransferase; leucine L-norleucine: 2-oxoglutarate aminotransferase. Enzyme Commission Number: EC 2.6.1.67. CAS No. 111310-35-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2908; 2-aminohexanoate transaminase; EC 2.6.1.67; 111310-35-1; norleucine transaminase; norleucine (leucine) aminotransferase; leucine L-norleucine: 2-oxoglutarate aminotransferase. Cat No: EXWM-2908.
2-aminomuconate deaminase
2-Aminomuconate is an intermediate in the bacterial biodegradation of nitrobenzene. The enzyme has been isolated from several species, including Pseudomonas pseudocaligenes JS45, Pseudomonas fluorescens KU-7, Pseudomonas sp. AP3 and Burkholderia cenocepacia J2315. The reaction is spontaneous in acid conditions. Group: Enzymes. Synonyms: amnD (gene name); nbaF (gene name). Enzyme Commission Number: EC 3.5.99.5. CAS No. 201098-29-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4588; 2-aminomuconate deaminase; EC 3.5.99.5; 201098-29-5; amnD (gene name); nbaF (gene name). Cat No: EXWM-4588.
The enzyme, characterized from the bacterium Comamonas testosteroni CNB-1, converts 2-aminomuconate to 2-hydroxyhexa-2,4-dienedioate, unlike the enzymes from Pseudomonas, which produce (3E)-2-oxohex-3-enedioate (see EC 3.5.99.5, 2-aminomuconate deaminase). The enzyme also acts on 2-amino-5-chloromuconate. Group: Enzymes. Synonyms: cnbZ (gene name). Enzyme Commission Number: EC 3.5.1.120. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4401; 2-aminomuconate deaminase (2-hydroxymuconate-forming); EC 3.5.1.120; cnbZ (gene name). Cat No: EXWM-4401.
2-aminophenol 1,6-dioxygenase
The enzyme, a member of the nonheme-iron(II)-dependent dioxygenase family, is an extradiol-type dioxygenase that utilizes a non-heme ferrous iron to cleave the aromatic ring at the meta position (relative to the hydroxyl substituent). The enzyme also has some activity with 2-amino-5-methylphenol and 2-amino-4-methylphenol. The enzyme from the bacterium Comamonas testosteroni CNB-1 also has the activity of EC 1.13.11.76, 2-amino-5-chlorophenol 1,6-dioxygenase. Group: Enzymes. Synonyms: amnA (gene name); amnB (gene name); 2-aminophenol:oxygen 1,6-oxidoreductase (decyclizing). Enzyme Commission Number: EC 1.13.11.74. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0594; 2-aminophenol 1,6-dioxygenase; EC 1.13.11.74; amnA (gene name); amnB (gene name); 2-aminophenol:oxygen 1,6-oxidoreductase (decyclizing). Cat No: EXWM-0594.
2-carboxy-1,4-naphthoquinone phytyltransferase
This enzyme, found in plants and cyanobacteria, catalyses a step in the synthesis of phylloquinone (vitamin K1), an electron carrier associated with photosystem I. The enzyme catalyses the transfer of the phytyl chain synthesized by EC 1.3.1.83, geranylgeranyl diphosphate reductase, to 2-carboxy-1,4-naphthoquinone. Group: Enzymes. Synonyms: menA (gene name); ABC4 (gene name); 1,4-dioxo-2-naphthoate phytyltransferase; 1,4-diketo-2-naphthoate phytyltransferase. Enzyme Commission Number: EC 2.5.1.130. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2746; 2-carboxy-1,4-naphthoquinone phytyltransferase; EC 2.5.1.130; menA (gene name); ABC4 (gene name); 1,4-dioxo-2-naphthoate phytyltransferase; 1,4-diketo-2-naphthoate phytyltransferase. Cat No: EXWM-2746.
2-carboxy-D-arabinitol-1-phosphatase
This enzyme belongs to the family of hydrolases, to be specific, those acting on phosphoric monoester bonds. Group: Enzymes. Synonyms: 2-carboxyarabinitol 1-phosphatase; 2-carboxy-D-arabinitol 1-phosphate phosphohydrolase. Enzyme Commission Number: EC 3.1.3.63. CAS No. 122319-88-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3668; 2-carboxy-D-arabinitol-1-phosphatase; EC 3.1.3.63; 122319-88-4; 2-carboxyarabinitol 1-phosphatase; 2-carboxy-D-arabinitol 1-phosphate phosphohydrolase. Cat No: EXWM-3668.
This enzyme belongs to the family of isomerases, specifically cis-trans isomerases. This enzyme participates in 1,4-dichlorobenzene degradation. Group: Enzymes. Synonyms: 2-chlorocarboxymethylenebutenolide isomerase; chlorodienelactone isomerase. Enzyme Commission Number: EC 5.2.1.10. CAS No. 115629-29-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5442; 2-chloro-4-carboxymethylenebut-2-en-1,4-olide isomerase; EC 5.2.1.10; 115629-29-3; 2-chlorocarboxymethylenebutenolide isomerase; chlorodienelactone isomerase. Cat No: EXWM-5442.
The enzyme from Escherichia coli requires Mg2+ or Mn2+. Forms part of an alternative nonmevalonate pathway for terpenoid biosynthesis (for diagram, click here). Group: Enzymes. Synonyms: MECDP-synthase; 2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol CMP-lyase (cyclizing). Enzyme Commission Number: EC 4.6.1.12. CAS No. 287480-92-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5349; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; EC 4.6.1.12; 287480-92-6; MECDP-synthase; 2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol CMP-lyase (cyclizing). Cat No: EXWM-5349.
The enzyme from Escherichia coli requires Mg2+ or Mn2+. ATP or UTP can replace CTP, but both are less effective. GTP and TTP are not substrates. Forms part of an alternative nonmevalonate pathway for terpenoid biosynthesis (for diagram, click here). Group: Enzymes. Synonyms: MEP cytidylyltransferase. Enzyme Commission Number: EC 2.7.7.60. CAS No. 251990-59-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3272; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; EC 2.7.7.60; 251990-59-7; MEP cytidylyltransferase. Cat No: EXWM-3272.
2-coumarate O-β-glucosyltransferase
Coumarinate (cis-2-hydroxycinnamate) does not act as acceptor. Group: Enzymes. Synonyms: uridine diphosphoglucose-o-coumarate glucosyltransferase; UDPG:o-coumaric acid O-glucosyltransferase. Enzyme Commission Number: EC 2.4.1.114. CAS No. 73665-97-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2340; 2-coumarate O-β-glucosyltransferase; EC 2.4.1.114; 73665-97-1; uridine diphosphoglucose-o-coumarate glucosyltransferase; UDPG:o-coumaric acid O-glucosyltransferase. Cat No: EXWM-2340.
2-coumarate reductase
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 3-(2-hydroxyphenyl)propanoate:NAD+ oxidoreductase. This enzyme is also called melilotate dehydrogenase. This enzyme participates in phenylalanine metabolism. Group: Enzymes. Synonyms: melilotate dehydrogenase. Enzyme Commission Number: EC 1.3.1.11. CAS No. 37251-10-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1282; 2-coumarate reductase; EC 1.3.1.11; 37251-10-8; melilotate dehydrogenase. Cat No: EXWM-1282.
Involved in the biosynthetic pathway of kanamycins. The enzyme characterized from the bacterium Streptomyces kanamyceticus can also accept UDP-α-D-glucose with lower efficiency. Group: Enzymes. Synonyms: kanE (gene name); kanM2 (gene name). Enzyme Commission Number: EC 2.4.1.301. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2536; 2'-deamino-2'-hydroxyneamine 1-α-D-kanosaminyltransferase; EC 2.4.1.301; kanE (gene name); kanM2 (gene name). Cat No: EXWM-2536.
2'-deamino-2'-hydroxyneamine transaminase
The reaction occurs in vivo in the opposite direction. Involved in the biosynthetic pathway of kanamycin A and kanamycin D. The enzyme, characterized from the bacterium Streptomyces kanamyceticus, can also catalyse EC 2.6.1.93, neamine transaminase. Group: Enzymes. Synonyms: kacL (gene name). Enzyme Commission Number: EC 2.6.1.94. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2935; 2'-deamino-2'-hydroxyneamine transaminase; EC 2.6.1.94; kacL (gene name). Cat No: EXWM-2935.
2-dehydro-3,6-dideoxy-6-sulfogluconate aldolase
The enzyme, characterized from the bacterium Pseudomonas putida SQ1, participates in a sulfoquinovose degradation pathway. Group: Enzymes. Synonyms: KDSG aldolase. Enzyme Commission Number: EC 4.1.2.58. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4895; 2-dehydro-3,6-dideoxy-6-sulfogluconate aldolase; EC 4.1.2.58; KDSG aldolase. Cat No: EXWM-4895.
2-dehydro-3-deoxy-6-phosphogalactonate aldolase
The enzyme catalyses the last reaction in a D-galactose degradation pathway. cf. EC 4.1.2.55, 2-dehydro-3-deoxy-phosphogluconate/2-dehydro-3-deoxy-6-phosphogalactonate aldolase. Group: Enzymes. Synonyms: 6-phospho-2-keto-3-deoxygalactonate aldolase; phospho-2-keto-3-deoxygalactonate aldolase; 2-keto-3-deoxy-6-phosphogalactonic aldolase; phospho-2-keto-3-deoxygalactonic aldolase; 2-keto-3-deoxy-6-phosphogalactonic acid aldolase; (KDPGal)aldolase; 2-dehydro-3-deoxy-D-galactonate-6-phosphate D-glyceraldehyde-3-phosphate-lyase; 2-dehydro-3-deoxy-D-galactonate-6-phosphate D-glyceraldehyde-3-phosphate-lyase (pyruvate-forming). Enzyme Commission Number: EC 4.1.2.21. CAS No. 9030-99-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4860; 2-dehydro-3-deoxy-6-phosphogalactonate aldolase; EC 4.1.2.21; 9030-99-3; 6-phospho-2-keto-3-deoxygalactonate aldolase; phospho-2-keto-3-deoxygalactonate aldolase; 2-keto-3-deoxy-6-phosphogalactonic aldolase; phospho-2-keto-3-deoxygalactonic aldolase; 2-keto-3-deoxy-6-phosphogalactonic acid aldolase; (KDPGal)aldolase; 2-dehydro-3-deoxy-D-galactonate-6-phosphate D-glyceraldehyde-3-phosphate-lyase; 2-dehydro-3-deoxy-D-galactonate-6-phosphate D-glyceraldehyde-3-phosphate-lyase (pyruvate-forming). Cat No: EXWM-4860.
2-dehydro-3-deoxy-D-arabinonate dehydratase
The enzyme participates in pentose oxidation pathways that convert pentose sugars to the tricarboxylic acid cycle intermediate 2-oxoglutarate. Group: Enzymes. Enzyme Commission Number: EC 4.2.1.141. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4982; 2-dehydro-3-deoxy-D-arabinonate dehydratase; EC 4.2.1.141. Cat No: EXWM-4982.
2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase
The enzyme from Pseudomonas acts equally well on NAD+ or NADP+, while that from Erwinia chrysanthemi and Escherichia coli is more specific for NAD+. Group: Enzymes. Synonyms: 2-keto-3-deoxygluconate 5-dehydrogenase; 2-keto-3-deoxy-D-gluconate dehydrogenase; 2-keto-3-deoxygluconate (nicotinamide adenine dinucleotide (phosphate)) dehydrogenase; 2-keto-3-deoxy-D-gluconate (3-deoxy-D-glycero-2,5-hexodiulosonic acid) dehydrogenase. Enzyme Commission Number: EC 1.1.1.127. CAS No. 37250-56-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0031; 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase; EC 1.1.1.127; 37250-56-9; 2-keto-3-deoxygluconate 5-dehydrogenase; 2-keto-3-deoxy-D-gluconate dehydrogenase; 2-keto-3-deoxygluconate (nicotinamide adenine dinucleotide (phosphate)) dehydrogenase; 2-keto-3-deoxy-D-gluconate (3-deoxy-D-glycero-2,5-hexodiulosonic acid) dehydrogenase. Cat No: EXWM-0031.
2-dehydro-3-deoxy-D-gluconate 6-dehydrogenase
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 2-dehydro-3-deoxy-D-gluconate:NADP+ 6-oxidoreductase. Other names in common use include 2-keto-3-deoxy-D-gluconate dehydrogenase, and 2-keto-3-deoxygluconate dehydrogenase. Group: Enzymes. Synonyms: 2-keto-3-deoxy-D-gluconate dehydrogenase; 2-keto-3-deoxygluconate dehydrogenase. Enzyme Commission Number: EC 1.1.1.126. CAS No. 37250-55-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0030; 2-dehydro-3-deoxy-D-gluconate 6-dehydrogenase; EC 1.1.1.126; 37250-55-8; 2-keto-3-deoxy-D-gluconate dehydrogenase; 2-keto-3-deoxygluconate dehydrogenase. Cat No: EXWM-0030.
2-dehydro-3-deoxy-D-gluconate aldolase
The enzyme from the archaeon Picrophilus torridus is involved in D-glucose and D-galactose catabolism via the nonphosphorylative variant of the Entner-Doudoroff pathway. In the direction of aldol synthesis the enzyme catalyses the formation of 2-dehydro-3-deoxy-D-gluconate and 2-dehydro-3-deoxy-D-galactonate at a similar ratio. It shows no activity with 2-dehydro-3-deoxy-D-gluconate 6-phosphate. cf. EC 4.1.2.14, 2-dehydro-3-deoxy-phosphogluconate aldolase. Group: Enzymes. Synonyms: Pto1279 (gene name); KDGA; KDG-specific aldolase. Enzyme Commission Number: EC 4.1.2.51. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4888; 2-dehydro-3-deoxy-D-gluconate aldolase; EC 4.1.2.51; Pto1279 (gene name); KDGA; KDG-specific aldolase. Cat No: EXWM-4888.
2-dehydro-3-deoxy-D-pentonate aldolase
This enzyme belongs to the family of lyases, specifically the aldehyde-lyases, which cleave carbon-carbon bonds. This enzyme participates in pentose and glucuronate interconversions. Group: Enzymes. Synonyms: 2-keto-3-deoxy-D-pentonate aldolase; 3-deoxy-D-pentulosonic acid aldolase; 2-dehydro-3-deoxy-D-pentonate glycolaldehyde-lyase. Enzyme Commission Number: EC 4.1.2.28. CAS No. 55326-36-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4867; 2-dehydro-3-deoxy-D-pentonate aldolase; EC 4.1.2.28; 55326-36-8; 2-keto-3-deoxy-D-pentonate aldolase; 3-deoxy-D-pentulosonic acid aldolase; 2-dehydro-3-deoxy-D-pentonate glycolaldehyde-lyase. Cat No: EXWM-4867.
2-dehydro-3-deoxygalactonokinase
This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is ATP:2-dehydro-3-deoxy-D-galactonate 6-phosphotransferase. Other names in common use include 2-keto-3-deoxygalactonokinase, 2-keto-3-deoxygalactonate kinase (phosphorylating), and 2-oxo-3-deoxygalactonate kinase. This enzyme participates in galactose metabolism. Group: Enzymes. Synonyms: 2-keto-3-deoxygalactonokinase; 2-keto-3-deoxygalactonate kinase (phosphorylating); 2-oxo-3-deoxygalactonate kinase. Enzyme Commission Number: EC 2.7.1.58. CAS No. 37278-05-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3088; 2-dehydro-3-deoxygalactonokinase; EC 2.7.1.58; 37278-05-0; 2-keto-3-deoxygalactonokinase; 2-keto-3-deoxygalactonate kinase (phosphorylating); 2-oxo-3-deoxygalactonate kinase. Cat No: EXWM-3088.
2-dehydro-3-deoxyglucarate aldolase
This enzyme belongs to the family of lyases, specifically the aldehyde-lyases, which cleave carbon-carbon bonds. This enzyme participates in ascorbate and aldarate metabolism. Group: Enzymes. Synonyms: 2-keto-3-deoxyglucarate aldolase; α-keto-β-deoxy-D-glucarate aldolase; 2-dehydro-3-deoxy-D-glucarate tartronate-semialdehyde-lyase; 2-dehydro-3-deoxy-D-glucarate tartronate-semialdehyde-lyase (pyruvate-forming). Enzyme Commission Number: EC 4.1.2.20. CAS No. 37290-56-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4859; 2-dehydro-3-deoxyglucarate aldolase; EC 4.1.2.20; 37290-56-5; 2-keto-3-deoxyglucarate aldolase; α-keto-β-deoxy-D-glucarate aldolase; 2-dehydro-3-deoxy-D-glucarate tartronate-semialdehyde-lyase; 2-dehydro-3-deoxy-D-glucarate tartronate-semialdehyde-lyase (pyruvate-forming). Cat No: EXWM-4859.
2-dehydro-3-deoxyglucono/galactono-kinase
The enzyme from the archaeon Sulfolobus solfataricus is involved in glucose and galactose catabolism via the branched variant of the Entner-Doudoroff pathway. It phosphorylates 2-dehydro-3-deoxy-D-gluconate and 2-dehydro-3-deoxy-D-galactonate with similar catalytic efficiency. cf. EC 2.7.1.45, 2-dehydro-3-deoxygluconokinase and EC 2.7.1.58, 2-dehydro-3-deoxygalactonokinase. Group: Enzymes. Synonyms: KDG kinase (ambiguous); KDGK (ambiguous); 2-keto-3-deoxy-D-gluconate kinase (ambiguous). Enzyme Commission Number: EC 2.7.1.178. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3009; 2-dehydro-3-deoxyglucono/galactono-kinase; EC 2.7.1.178; KDG kinase (ambiguous); KDGK (ambiguous); 2-keto-3-deoxy-D-gluconate kinase (ambiguous). Cat No: EXWM-3009.
2-dehydro-3-deoxygluconokinase
The enzyme shows no activity with 2-dehydro-3-deoxy-D-galactonate. cf. EC 2.7.1.178, 2-dehydro-3-deoxyglucono/2-dehydro-3-deoxygalactonokinase. Group: Enzymes. Synonyms: 2-keto-3-deoxygluconokinase; 2-keto-3-deoxy-D-gluconic acid kinase; 2-keto-3-deoxygluconokinase (phosphorylating); 2-keto-3-deoxygluconate kinase; ketodeoxygluconokinase. Enzyme Commission Number: EC 2.7.1.45. CAS No. 9026-54-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3075; 2-dehydro-3-deoxygluconokinase; EC 2.7.1.45; 9026-54-4; 2-keto-3-deoxygluconokinase; 2-keto-3-deoxy-D-gluconic acid kinase; 2-keto-3-deoxygluconokinase (phosphorylating); 2-keto-3-deoxygluconate kinase; ketodeoxygluconokinase. Cat No: EXWM-3075.
2-dehydro-3-deoxy-L-arabinonate dehydratase
This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. This enzyme participates in ascorbate and aldarate metabolism. Group: Enzymes. Synonyms: 2-keto-3-deoxy-L-arabinonate dehydratase; 2-dehydro-3-deoxy-L-arabinonate hydro-lyase. Enzyme Commission Number: EC 4.2.1.43. CAS No. 37263-10-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5032; 2-dehydro-3-deoxy-L-arabinonate dehydratase; EC 4.2.1.43; 37263-10-8; 2-keto-3-deoxy-L-arabinonate dehydratase; 2-dehydro-3-deoxy-L-arabinonate hydro-lyase. Cat No: EXWM-5032.
2-dehydro-3-deoxy-L-galactonate 5-dehydrogenase
The enzyme, characterized from agarose-degrading bacteria, is involved in a degradation pathway for 3,6-anhydro-α-L-galactopyranose, a major component of the polysaccharides of red macroalgae. Group: Enzymes. Enzyme Commission Number: EC 1.1.1.389. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0308; 2-dehydro-3-deoxy-L-galactonate 5-dehydrogenase; EC 1.1.1.389. Cat No: EXWM-0308.
2-dehydro-3-deoxy-L-pentonate aldolase
This enzyme belongs to the family of lyases, specifically the aldehyde-lyases, which cleave carbon-carbon bonds. This enzyme participates in fructose and mannose metabolism. Group: Enzymes. Synonyms: 2-keto-3-deoxy-L-pentonate aldolase; 2-keto-3-deoxy-L-arabonate aldolase; 2-keto-3-deoxy-D-xylonate aldolase; 3-deoxy-D-pentulosonic acid aldolase; 2-dehydro-3-deoxy-L-pentonate glycolaldehyde-lyase. Enzyme Commission Number: EC 4.1.2.18. CAS No. 9076-49-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4856; 2-dehydro-3-deoxy-L-pentonate aldolase; EC 4.1.2.18; 9076-49-7; 2-keto-3-deoxy-L-pentonate aldolase; 2-keto-3-deoxy-L-arabonate aldolase; 2-keto-3-deoxy-D-xylonate aldolase; 3-deoxy-D-pentulosonic acid aldolase; 2-dehydro-3-deoxy-L-pentonate glycolaldehyde-lyase. Cat No: EXWM-4856.
The enzyme, characterized from the bacteria Sphingomonas sp. SKA58 and Sulfobacillus thermosulfidooxidans, is involved in the non-phosphorylative degradation pathway for L-rhamnose. It does not show any detectable activity with NADP+ or with other aldoses. Group: Enzymes. Synonyms: 2-keto-3-deoxy-L-rhamnonate dehydrogenase. Enzyme Commission Number: EC 1.1.1.401. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0323; 2-dehydro-3-deoxy-L-rhamnonate dehydrogenase (NAD+); EC 1.1.1.401; 2-keto-3-deoxy-L-rhamnonate dehydrogenase. Cat No: EXWM-0323.
In the archaeon Sulfolobus solfataricus the enzyme is involved in glucose and galactose catabolism via the branched variant of the Entner-Doudoroff pathway. It utilizes 2-dehydro-3-deoxy-6-phosphate-D-gluconate and 2-dehydro-3-deoxy-6-phosphate-D-galactonate with similar catalytic efficiency. In vitro the enzyme can also catalyse the cleavage of the non-phosphorylated forms 2-dehydro-3-deoxy-D-gluconate and 2-dehydro-3-deoxy-D-galactonate with much lower catalytic efficiency. cf. EC 4.1.2.21, 2-dehydro-3-deoxy-6-phosphogalactonate aldolase, and EC 4.1.2.14, 2-dehydro-3-deoxy-phosphogluconate aldolase. Group: Enzymes. Synonyms: 2-keto-3-deoxygluconate aldolase (ambiguous); KDGA (ambiguous). Enzyme Commission Number: EC 4.1.2.55. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4892; 2-dehydro-3-deoxy-phosphogluconate/2-dehydro-3-deoxy-6-phosphogalactonate aldolase; EC 4.1.2.55; 2-keto-3-deoxygluconate aldolase (ambiguous); KDGA (ambiguous). Cat No: EXWM-4892.
2-dehydro-3-deoxy-phosphogluconate aldolase
The enzyme shows no activity with 2-dehydro-3-deoxy-6-phosphate-D-galactonate. cf. EC 4.1.2.55, 2-dehydro-3-deoxy-phosphogluconate/2-dehydro-3-deoxy-6-phosphogalactonate aldolase. Also acts on 2-oxobutanoate. Group: Enzymes. Synonyms: phospho-2-keto-3-deoxygluconate aldolase; KDPG aldolase; phospho-2-keto-3-deoxygluconic aldolase; 2-keto-3-deoxy-6-phosphogluconic aldolase; 2-keto-3-deoxy-6-phosphogluconate aldolase; 6-phospho-2-keto-3-deoxygluconate aldolase; ODPG aldolase; 2-oxo-3-deoxy-6-phosphogluconate aldolase; 2-. Enzyme Commission Number: EC 4.1.2.14. CAS No. 9024-53-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4854; 2-dehydro-3-deoxy-phosphogluconate aldolase; EC 4.1.2.14; 9024-53-7; phospho-2-keto-3-deoxygluconate aldolase; KDPG aldolase; phospho-2-keto-3-deoxygluconic aldolase; 2-keto-3-deoxy-6-phosphogluconic aldolase; 2-keto-3-deoxy-6-phosphogluconate aldolase; 6-phospho-2-keto-3-deoxygluconate aldolase; ODPG aldolase; 2-oxo-3-deoxy-6-phosphogluconate aldolase; 2-keto-3-deoxygluconate-6-P-aldolase; 2-keto-3-deoxygluconate-6-phosphate aldolase; 2-dehydro-3-deoxy-D-gluconate-6-phosphate D-glyceraldehyde-3-phosphate-lyase; 2-dehydro-3-deoxy-D-gluconate-6-phosphate D-glyceraldehyde-3-phosphate-lyase (pyruvate-forming). Cat No: EXWM-4854.
2'-dehydrokanamycin reductase
Found in the bacterium Streptomyces kanamyceticus where it is involved in the conversion of kanamycin B to kanamycin A. Group: Enzymes. Synonyms: kanK (gene name, ambiguous). Enzyme Commission Number: EC 1.1.1.355. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0271; 2'-dehydrokanamycin reductase; EC 1.1.1.355; kanK (gene name, ambiguous). Cat No: EXWM-0271.
2-dehydropantoate 2-reductase
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (R)-pantoate:NADP+ 2-oxidoreductase. Other names in common use include 2-oxopantoate reductase, 2-ketopantoate reductase, 2-ketopantoic acid reductase, ketopantoate reductase, and ketopantoic acid reductase. This enzyme participates in pantothenate and coa biosynthesis. Group: Enzymes. Synonyms: 2-oxopantoate reductase; 2-ketopantoate reductase; 2-ketopantoic acid reductase; ketopantoate reductase; ketopantoic acid reductase. Enzyme Commission Number: EC 1.1.1.169. CAS No. 37211-74-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0072; 2-dehydropantoate 2-reductase; EC 1.1.1.169; 37211-74-8; 2-oxopantoate reductase; 2-ketopantoate reductase; 2-ketopantoic acid reductase; ketopantoate reductase; ketopantoic acid reductase. Cat No: EXWM-0072.
2-dehydropantoate aldolase
This enzyme belongs to the family of lyases, specifically the aldehyde-lyases, which cleave carbon-carbon bonds. Group: Enzymes. Synonyms: ketopantoaldolase; 2-dehydropantoate formaldehyde-lyase. Enzyme Commission Number: EC 4.1.2.12. CAS No. 9024-51-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4852; 2-dehydropantoate aldolase; EC 4.1.2.12; 9024-51-5; ketopantoaldolase; 2-dehydropantoate formaldehyde-lyase. Cat No: EXWM-4852.
2-dehydropantolactone reductase
The enzyme participates in an alternative pathway for biosynthesis of (R)-pantothenate (vitamin B5). This entry covers enzymes whose stereo specificity for NADP+ is not known. cf. EC 1.1.1.168 2-dehydropantolactone reductase (Re-specific) and EC 1.1.1.214, 2-dehydropantolactone reductase (Si-specific). Group: Enzymes. Synonyms: 2-oxopantoyl lactone reductase; 2-ketopantoyl lactone reductase; ketopantoyl lactone reductase; 2-dehydropantoyl-lactone reductase. Enzyme Commission Number: EC 1.1.1.358. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0274; 2-dehydropantolactone reductase; EC 1.1.1.358; 2-oxopantoyl lactone reductase; 2-ketopantoyl lactone reductase; ketopantoyl lactone reductase; 2-dehydropantoyl-lactone reductase. Cat No: EXWM-0274.
2-dehydropantolactone reductase (Re-specific)
The yeast enzyme differs from that from Escherichia coli [EC 1.1.1.214 2-dehydropantolactone reductase (Si-specific)], which is specific for the Si-face of NADP+, and in receptor requirements from EC 1.1.99.26 3-hydroxycyclohexanone dehydrogenase. Group: Enzymes. Synonyms: 2-oxopantoyl lactone reductase; ketopantoyl lactone reductase; 2-ketopantoyl lactone reductase; 2-dehydropantoyl-lactone reductase (A-specific); (R)-pantolactone:NADP+ oxidoreductase (A-specific); 2-dehydropantolactone reductase (A-specific). Enzyme Commission Number: EC 1.1.1.168. CAS No. 37211-75-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0071; 2-dehydropantolactone reductase (Re-specific); EC 1.1.1.168; 37211-75-9; 2-oxopantoyl lactone reductase; ketopantoyl lactone reductase; 2-ketopantoyl lactone reductase; 2-dehydropantoyl-lactone reductase (A-specific); (R)-pantolactone:NADP+ oxidoreductase (A-specific); 2-dehydropantolactone reductase (A-specific). Cat No: EXWM-0071.
2-dehydropantolactone reductase (Si-specific)
The Escherichia coli enzyme differs from that from yeast [EC 1.1.1.168 2-dehydropantolactone reductase (Re-specific)], which is specific for the Re-face of NADP+, and in receptor requirements from EC 1.1.99.26 3-hydroxycyclohexanone dehydrogenase. Group: Enzymes. Synonyms: 2-oxopantoyl lactone reductase; 2-ketopantoyl lactone reductase; ketopantoyl lactone reductase; 2-dehydropantoyl-lactone reductase (B-specific); (R)-pantolactone:NADP+ oxidoreductase (B-specific); 2-dehydropantolactone reductase (B-specific). Enzyme Commission Number: EC 1.1.1.214. CAS No. 37211-75-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0119; 2-dehydropantolactone reductase (Si-specific); EC 1.1.1.214; 37211-75-9; 2-oxopantoyl lactone reductase; 2-ketopantoyl lactone reductase; ketopantoyl lactone reductase; 2-dehydropantoyl-lactone reductase (B-specific); (R)-pantolactone:NADP+ oxidoreductase (B-specific); 2-dehydropantolactone reductase (B-specific). Cat No: EXWM-0119.
2'-deoxyadenosine kinase
2'-Deoxyguanosine can also act as acceptor. Possibly identical with EC 2.7.1.74 deoxycytidine kinase. Group: Enzymes. Synonyms: purine-deoxyribonucleoside kinase; deoxyadenosine kinase (phosphorylating) (ambiguous); purine-deoxyribonucleoside kinase (ambiguous); deoxyadenosine kinase (ambiguous); ATP:deoxyadenosine 5'-phosphotransferase (ambiguous). Enzyme Commission Number: EC 2.7.1.76. CAS No. 37278-12-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3105; 2'-deoxyadenosine kinase; EC 2.7.1.76; 37278-12-9; purine-deoxyribonucleoside kinase; deoxyadenosine kinase (phosphorylating) (ambiguous); purine-deoxyribonucleoside kinase (ambiguous); deoxyadenosine kinase (ambiguous); ATP:deoxyadenosine 5'-phosphotransferase (ambiguous). Cat No: EXWM-3105.
2-deoxy-D-gluconate 3-dehydrogenase
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 2-deoxy-D-gluconate:NAD+ 3-oxidoreductase. This enzyme is also called 2-deoxygluconate dehydrogenase. This enzyme participates in pentose and glucuronate interconversions. Group: Enzymes. Synonyms: 2-deoxygluconate dehydrogenase. Enzyme Commission Number: EC 1.1.1.125. CAS No. 37250-54-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0029; 2-deoxy-D-gluconate 3-dehydrogenase; EC 1.1.1.125; 37250-54-7; 2-deoxygluconate dehydrogenase. Cat No: EXWM-0029.
2-deoxyglucose-6-phosphatase
Also active towards fructose 1-phosphate. Group: Enzymes. Synonyms: 2-deoxyglucose-6-phosphate phosphatase. Enzyme Commission Number: EC 3.1.3.68. CAS No. 65187-56-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3672; 2-deoxyglucose-6-phosphatase; EC 3.1.3.68; 65187-56-6; 2-deoxyglucose-6-phosphate phosphatase. Cat No: EXWM-3672.
2-deoxyglucosidase
This enzyme belongs to the family of hydrolases, specifically those glycosidases that hydrolyse O- and S-glycosyl compounds. Group: Enzymes. Synonyms: 2-deoxy-α-glucosidase; 2-deoxy-α-D-glucosidase. Enzyme Commission Number: EC 3.2.1.112. CAS No. 92480-05-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3795; 2-deoxyglucosidase; EC 3.2.1.112; 92480-05-2; 2-deoxy-α-glucosidase; 2-deoxy-α-D-glucosidase. Cat No: EXWM-3795.
2'-deoxymugineic-acid 2'-dioxygenase
Requires iron(II). It is also likely that this enzyme can catalyse the hydroxylation of 3-epihydroxy-2'-deoxymugineic acid to form 3-epihydroxymugineic acid. Group: Enzymes. Synonyms: IDS3. Enzyme Commission Number: EC 1.14.11.24. CAS No. 133758-62-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0641; 2'-deoxymugineic-acid 2'-dioxygenase; EC 1.14.11.24; 133758-62-0; IDS3. Cat No: EXWM-0641.
2-Deoxyribose 5-phosphate Aldolase from E. coli, Recombinant
Deoxyriboaldolase catalyzes the condensation of acetaldehyde and glyceraldehyde 3-phosphate to 2-deoxyribose 5-phosphate. This enzyme belongs to the family of lyases, specifically the aldehyde-lyases, which cleave carbon-carbon bonds. This enzyme participates in pentose phosphate pathway. Group: Enzymes. Synonyms: 2-deoxy-D-ribose-5-phosphate acetaldehyde-lyase (D-glyceraldehyde-3-phosphate-forming); phosphodeoxyriboaldolase; deoxyriboaldolase; deoxyribose-5-phosphate aldolase; 2-deoxyribose-5-phosphate aldolase; 2-deoxy-D-ribose-5-phosphate acetaldehyde-lyase; deoxyribose-phosphate aldolase; EC 4.1.2.4; DERA; 9026-97-5. Enzyme Commission Number: EC 4.1.2.4. CAS No. 9026-97-5. DERA. Activity: >2 U/mg. Storage: Store at -20°C. Source: E. coli K12. Species: E. coli. 2-deoxy-D-ribose-5-phosphate acetaldehyde-lyase (D-glyceraldehyde-3-phosphate-forming); phosphodeoxyriboaldolase; deoxyriboaldolase; deoxyribose-5-phosphate aldolase; 2-deoxyribose-5-phosphate aldolase; 2-deoxy-D-ribose-5-phosphate acetaldehyde-lyase; deoxyribose-phosphate aldolase; EC 4.1.2.4; DERA; 9026-97-5. Cat No: NATE-0794.
2-deoxy-scyllo-inosamine dehydrogenase
Requires zinc. Involved in the biosynthetic pathways of several clinically important aminocyclitol antibiotics, including kanamycin, neomycin and ribostamycin. cf. EC 1.1.99.38, 2-deoxy-scyllo-inosamine dehydrogenase (AdoMet-dependent). Group: Enzymes. Synonyms: neoA (gene name); kanK (gene name, ambiguous); kanE (gene name, ambiguous). Enzyme Commission Number: EC 1.1.1.329. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0242; 2-deoxy-scyllo-inosamine dehydrogenase; EC 1.1.1.329; neoA (gene name); kanK (gene name, ambiguous); kanE (gene name, ambiguous). Cat No: EXWM-0242.
Involved in the biosynthetic pathway of the aminoglycoside antibiotics of the butirosin family. The enzyme from Bacillus circulans was shown to be a radical S-adenosyl-L-methionine (SAM) enzyme. cf. EC 1.1.1.329, 2-deoxy-scyllo-inosamine dehydrogenase. Group: Enzymes. Synonyms: btrN (gene name); 2-deoxy-scyllo-inosamine dehydrogenase (SAM-dependent). Enzyme Commission Number: EC 1.1.99.38. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0466; 2-deoxy-scyllo-inosamine dehydrogenase (AdoMet-dependent); EC 1.1.99.38; btrN (gene name); 2-deoxy-scyllo-inosamine dehydrogenase (SAM-dependent). Cat No: EXWM-0466.
2-deoxy-scyllo-inosose synthase
Requires Co2+. Involved in the biosynthetic pathways of several clinically important aminocyclitol antibiotics, including kanamycin, butirosin, neomycin and ribostamycin. Requires an NAD+ cofactor, which is transiently reduced during the reaction. The enzyme from the bacterium Bacillus circulans forms a complex with the glutamine amidotransferase subunit of pyridoxal 5'-phosphate synthase (EC 4.3.3.6), which appears to stabilize the complex. Group: Enzymes. Synonyms: btrC (gene name); neoC (gene name); kanC (gene name). Enzyme Commission Number: EC 4.2.3.124. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5137; 2-deoxy-scyllo-inosose synthase; EC 4.2.3.124; btrC (gene name); neoC (gene name); kanC (gene name). Cat No: EXWM-5137.
2-deoxystreptamine glucosyltransferase
Involved in the biosynthesis of kanamycin B and kanamycin C. Also catalyses EC 2.4.1.283, 2-deoxystreptamine N-acetyl-D-glucosaminyltransferase, but activity is only one fifth of that with UDP-α-D-glucose. Group: Enzymes. Synonyms: kanF (gene name). Enzyme Commission Number: EC 2.4.1.284. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2517; 2-deoxystreptamine glucosyltransferase; EC 2.4.1.284; kanF (gene name). Cat No: EXWM-2517.
Involved in the biosynthetic pathways of several clinically important aminocyclitol antibiotics, including kanamycin, butirosin, neomycin and ribostamycin. Unlike the enzyme from the bacterium Streptomyces kanamyceticus, which can also accept UDP-D-glucose (cf. EC 2.4.1.284, 2-deoxystreptamine glucosyltransferase), the enzyme from Bacillus circulans can only accept UDP-N-acetyl-α-D-glucosamine. Group: Enzymes. Synonyms: btrM (gene name); neoD (gene name); kanF (gene name). Enzyme Commission Number: EC 2.4.1.283. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2516; 2-deoxystreptamine N-acetyl-D-glucosaminyltransferase; EC 2.4.1.283; btrM (gene name); neoD (gene name); kanF (gene name). Cat No: EXWM-2516.