MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Everolimus-d4 | Everolimus-d 4 is the deuterium labeled Everolimus. Everolimus (RAD001) is a Rapamycin derivative and a potent, selective and orally active mTOR1 inhibitor. Everolimus binds to FKBP-12 to generate an immunosuppressive complex. Everolimus inhibits tumor cells proliferation and induces cell apoptosis and autophagy. Everolimus has potent immunosuppressive and anticancer activities[1][2]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: RAD001-d4; SDZ-RAD-d4. CAS No. 1338452-54-2. Pack Sizes: 500 μg. Product ID: HY-10218S. |  |
| Evinacumab | Evinacumab (REGN1500) is a human anti- ANGPTL3 ( angiopoietin-like protein 3 ) monoclonal antibody (IgG4 class antibody). Evinacumab reduces plasma lipids in dyslipidemic mice by blocking ANGPTL3. Evinacumab can be used in studies of homozygous familial hypercholesterolaemia (HoFH), refractory hypercholesterolaemia (both familial and non-familial) and severe hypertriglyceridaemia [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: REGN1500. CAS No. 1446419-85-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P99194. | |
| Evobrutinib | Evobrutinib (M2951) is an orally active, potent, highly selective and irreversibly covalent BTK inhibitor, with an IC 50 of 8.9 nM. Evobrutinib (M2951) can be used for the research of autoimmune diseases [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: M2951; MSC2364447C. CAS No. 1415823-73-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101215. | |
| Evocalcet | Evocalcet (KHK7580) is an orally active calcium sensing receptor ( CaSR ) agonist. Evocalcet inhibits the secretion of parathyroid hormone (PTH) from parathyroid gland cells. Evocalcet can be used for the research of hyperparathyroidism [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KHK7580. CAS No. 870964-67-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17613. | |
| Evodenoson | Evodenoson is a selective agonist of the A 2A adenosine receptor. Evodenosons primary actions include reducing inflammatory responses, decreasing intestinal fluid secretion, edema, tissue damage, and neutrophil infiltration induced by Clostridium difficile toxin A. Evodenosons protective effect is achieved by reducing myeloperoxidase (MPO) and adenosine deaminase (ADA) activities, and by lowering the production of tumor necrosis factor-alpha (TNF-α) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ATL 313; DE 112. CAS No. 844873-47-8. Pack Sizes: 1 mg. Product ID: HY-105017. | |
| Evodiamine | Evodiamine is an alkaloid isolated from the fruit of Evodia rutaecarpa Bentham with diverse biological activities including anti-inflammatory, anti-obesity, and antitumor. Uses: Scientific research. Group: Natural products. Alternative Names: (+)-Evodiamine; d-Evodiamine. CAS No. 518-17-2. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 250 mg. Product ID: HY-N0114. | |
| Evofosfamide | Evofosfamide (TH-302) is a hypoxia -activated proagent with IC 50 of 10 μM and 1000 μM in hypoxia (N 2 ) and normoxia (21% O 2 ), respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TH-302. CAS No. 918633-87-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10535. | |
| Evogliptin tartrate | Evogliptin (DA-1229) tartrate is an orally active DPP4 inhibitor with significant and sustained hypoglycaemic effects in mouse models. Evogliptin tartrate also inhibits the production of inflammatory and fibrotic signals in hepatocytes by inducing autophagy. Evogliptin tartrate can be used in studies of type 2 diabetes, osteoporosis, renal impairment and chronic liver inflammation [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DA-1229 tartrate. CAS No. 1222102-51-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-117985B. | |
| Evolocumab | Evolocumab (AMG 145) is a human monoclonal antibody that inhibits PCSK9. Evolocumab is used in the study of hypercholesterolemia and atherosclerotic cardiovascular disease. Evolocumab binds to circulating PCSK9 protein and inhibits its binding to LDLR. Evolocumab has antioxidant and cytoprotective activities against H 2 O 2 -induced oxidative damage to endothelial cells. Evolocumab may also negatively regulate activation of the TLR-4/NF-κB signaling pathway to prevent inflammation [1] [2] [3]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: AMG 145. CAS No. 1256937-27-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9930. | |
| Evunzekibart | Evunzekibart (ATOR-1017) is an Fc-γ receptor conditional 4-1BB agonist and IgG4-type antibody. Evunzekibart can be used as monotherapy or in combination with anti-PD1 to exert anticancer activity. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: ATOR-1017. CAS No. 2639688-77-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990067. | |
| Evuzamitide | Evuzamitide is a diagnostic imaging agent. Evuzamitide as a pan-amyloid radiotracer binding to amyloid deposits from multiple amyloidogenic proteins. Evuzamitide can be used for the research of early diagnosis of amyloid cardiomyopathy (CMP) and monitoring [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 1420048-58-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P10023. | |
| Ex26 | Ex26 (S1P1-IN-Ex26) is a potent and selective sphingosine 1-phosphate receptor 1 ( S1P 1 ) antagonist ( IC 50=0.93 nM). Ex26 shows >3,000-fold selectivity for S1P 1 over other Sphingosine 1-phosphate receptors. Ex26 can be used in experimental autoimmune encephalomyelitis reseach [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: S1P1-IN-Ex26. CAS No. 1233332-37-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-117213. | |
| Exatecan | Exatecan (DX-8951) is a DNA topoisomerase I inhibitor, with an IC 50 of 2.2 μM (0.975 μg/mL), and can be used in cancer research. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DX-8951. CAS No. 171335-80-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13631. | |
| Exatecan mesylate | Exatecan mesylate (DX8951f) is a DNA topoisomerase I inhibitor, with an IC 50 of 2.2 μM (0.975 μg/mL). Exatecan mesylate can be used in cancer research. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DX8951f. CAS No. 169869-90-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-13631A. | |
| Exemestane | Exemestane (FCE 24304) is a selective, irreversible and orally active steroidal aromatase inhibitor with IC 50 s of 30 nM and 40 nM for human placenta l and rat ovarian aromatase , respectively. Exemestane can be used for hormone-dependent breast cancer research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FCE 24304; EXE. CAS No. 107868-30-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13632. | |
| Exemestane (Standard) | Exemestane (Standard) is the analytical standard of Exemestane. This product is intended for research and analytical applications. Exemestane (FCE 24304) is a selective, irreversible and orally active steroidal aromatase inhibitor with IC 50 s of 30 nM and 40 nM for human placenta l and rat ovarian aromatase , respectively. Exemestane can be used for hormone-dependent breast cancer research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FCE 24304(Standard); EXE (Standard). CAS No. 107868-30-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-13632R. | |
| Exendin-3 | Exendin-3 is a biologically active peptides isolated from venoms of the Gila monster lizards, Heloderma horridurn. Uses: Scientific research. Group: Peptides. CAS No. 130357-25-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P1543. | |
| Exendin-4 | Exendin-4 (Exenatide), a 39 amino acid peptide, is a long-acting glucagon-like peptide-1 receptor agonist with an IC 50 of 3.22 nM. Uses: Scientific research. Group: Peptides. Alternative Names: Exenatide. CAS No. 141758-74-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-13443. | |
| Exendin-4 acetate | Exendin-4 acetate (Exenatide acetate), a 39 amino acid peptide, is a long-acting glucagon-like peptide-1 receptor agonist with an IC 50 of 3.22 nM. Uses: Scientific research. Group: Peptides. Alternative Names: Exenatide acetate. CAS No. 914454-01-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-13443A. | |
| Exendin(9-39) amide | Exendin(9-39) amide (Avexitide) is a glucagon-like peptide-1 ( GLP-1 ) antagonist that competes with endogenous GLP-1 for binding to GLP-1 receptors, thereby antagonizing the effects of excess GLP-1 secretion. Exendin(9-39) amide can be used to study postoperative hypoglycemia (PBH) [1]. Uses: Scientific research. Group: Peptides. Alternative Names: Avexitide. CAS No. 133514-43-9. Pack Sizes: 500 μg; 1 mg; 5 mg. Product ID: HY-P0264. | |
| Exisulind | Exisulind is an inactive metabolite of the nonsteroidal, anti-inflammatory agent sulindac [1]. Exisulind inhibits aldose reductase with an IC 50 of 367 nM in vitro and may contribute to the beneficial pharmacological effects of sulindac on type 2 diabetic complications [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 59864-04-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-13633. | |
| Exlinkibart | Exlinkibart (LVGN-6051) targets TNFRSF9 and is an IgG1κ antibody humanized through complementarity-determining region (CDR) grafting technology. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: LVGN-6051. CAS No. 2642171-64-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990040. | |
| Exo1 | Exo1 is a chemical inhibitor of the exocytic pathway. Uses: Scientific research. Group: Signaling pathways. CAS No. 75541-83-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-112670. | |
| Exo2 | Exo2 is a secretion inhibitor. Exo2 perturbs trafficking of Shiga toxin between endosomes and the trans-Golgi network. Exo2 blocks secretory cargo exit from the ER (endoplasmic reticulum) and disrupts the Golgi apparatus, but does not affect the morphology of the TGN (trans-Golgi network) Exo2 can stimulate calcium-dependent exocytosis in permeabilized adrenal chromaff in cells [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 304684-77-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-137975. | |
| Exoenzyme C3, clostridium botulinum | Exoenzyme C3, clostridium botulinum is a promising agent to inactivate RhoA in neurons due to preventing the detrimental effect of active Rho in the recovery of injured neuronal systems. Exoenzyme C3, clostridium botulinum is used for the study of post-traumatic neuro-regeneration [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 58319-92-9. Pack Sizes: 25 μg. Product ID: HY-P2325. | |
| (E/Z)-4-Hydroxytamoxifen | (E/Z)-4-Hydroxytamoxifen (Afimoxifene) is a racemic compound of (Z)-4-Hydroxytamoxifen and (E)-4-Hydroxytamoxifen isomers. (E/Z)-4-Hydroxytamoxifen is a selective estrogen receptor modulator with mixed estrogenic and antiestrogenic activity, which is also an active metabolite of Tamoxifen (HY-13757A). (E/Z)-4-Hydroxytamoxifen is an agonist of the G protein-coupled estrogen receptor ( GPER ) with relatively low affinity (100-1000 nM). (E/Z)-4-Hydroxytamoxifen is promising for research of cyclical mastalgia, such as breast pain, tenderness, and nodularity [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: Afimoxifene; 4-OHT. CAS No. 68392-35-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16950A. | |
| Ezabenlimab | Ezabenlimab (BI-754091) is an anti- PD-1 mAb with binding constant K d value of 6 nM (CHO cells). Ezabenlimab blocks the interaction of PD-1 with PD-L1 and PD-L2. Ezabenlimab increases interferon-γ secretion in T cells, and inhibits tumor growth in vivo [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: BI-754091. CAS No. 2249882-54-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99610. | |
| Ezetimibe | Ezetimibe (SCH 58235) is a potent cholesterol absorption inhibitor. Ezetimibe is a Niemann-Pick C1-like1 ( NPC1L1 ) inhibitor, and is a potent Nrf2 activator. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SCH 58235. CAS No. 163222-33-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17376. | |
| Ezetimibe-d4 | Ezetimibe-d 4 is the deuterium labeled Ezetimibe. Ezetimibe is a Niemann-Pick C1-like1 (NPC1L1) inhibitor, and is a potent Nrf2 activator. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: SCH 58235-d4. CAS No. 1093659-90-5. Pack Sizes: 1 mg. Product ID: HY-17376S. | |
| Ezetimibe ketone | Ezetimibe ketone (EZM-K) is a phase-I metabolite of Ezetimibe. Ezetimibe is a Niemann-Pick C1-like1 ( NPC1L1 ) inhibitor, and is a potent Nrf2 activator. Ezetimibe is a potent cholesterol absorption inhibitor [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: EZM-K. CAS No. 191330-56-0. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-133114. | |
| Ezetimibe phenoxy glucuronide | Ezetimibe phenoxy glucuronide (Ezetimibe glucuronide) is the active metabolite of Ezetimibe. Antihyperlipoproteinemic activity [1]. Ezetimibe is a potent cholesterol absorption inhibitor [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ezetimibe glucuronide; Ezetimibe β-D-glucuronide. CAS No. 190448-57-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-135391. | |
| EZH2-IN-14 | EZH2-IN-14 is a selective EZH2 ( Histone Methyltransferase ) inhibitor with an IC 50 of 12 nM. EZH2-IN-14 inhibits the methyltransferase activity of EZH2/PRC2 (that is, reducing H3K27me3). EZH2-IN-14 shows >200-fold selective for EZH2 over the highly homologous H3K27 methyltransferase EZH1 [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1979157-17-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-148458. | |
| (E/Z)-N-Desethylsunitinib hydrochloride | (E/Z)-N-Desethylsunitinib hydrochloride ((E/Z)-SU-12662 hydrochloride) is a compound with potential anti-tumor activity that inhibits VEGF-R2 and PDGF-Rβ tyrosine kinases. (E/Z)-N-Desethylsunitinib hydrochloride is the main active metabolite of sunitinib and has the ability to competitively inhibit ATP [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (E/Z)-SU-12662 hydrochloride. CAS No. 1261432-05-6. Pack Sizes: 1 mg; 5 mg. Product ID: HY-138813A. | |
| Ezurpimtrostat hydrochloride | Ezurpimtrostat hydrochloride (compound 2-3) is a potent and orally active anti-fibrotic agent. Ezurpimtrostat hydrochloride reduces significantly the liver fibrosis in DEN (diethyl nitrosamine) cirrhotic rat model. Ezurpimtrostat hydrochloride can be used for the research of fibrosis, cancer, autophagy and cathepsins B (CTSB), L (CTSL) and D (CTSD) related diseases [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GNS561 hydrochloride. CAS No. 1914148-73-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-137978A. | |
| F092 | F092 is an inhibitor of hematopoietic prostaglandin D synthase ( H-PGDS ) with a K D value of 0.14 nM. F092 can be used in the study of allergic and inflammatory responses [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2250261-59-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-139171. | |
| F-1 | F-1 is a potent ALK and ROS1 dual inhibitor, suppresses phospho-ALK and its relative downstream signaling pathways, with IC 50 s of 2.1 nM, 2.3 nM, 1.3 nM and 3.9 nM for ALK WT , ROS1 WT , ALK L1196M and ALK G1202R , respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2244775-31-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112801. | |
| F16 | F16 is a potent growth inhibitor of the neu -overexpressing cells and also selectively inhibits proliferation of mammary epithelial as well as a variety of mouse mammary tumor and human breast cancer cell lines. Uses: Scientific research. Group: Signaling pathways. CAS No. 36098-33-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-100395. | |
| F7H | F7H is a Frizzled receptor FZD7 antagonist ( IC 50 : 1.25 μM). Frizzled receptors (FZDs) influence Wnt signaling, mediating embryonic development and tissue homeostasis. F7H is a potent ligand for the FZD7 transmembrane domain (TMD) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 897109-93-2. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-156095. | |
| Fabomotizole | Fabomotizole (CM346) is an insecticide with anxiolytic, antianxiety, and neuroprotective activities and a substrate of p-glycoprotein. Fabomotizole inhibits the ST-segment depression induced by isoproterenol in a rat model of acute subendocardial ischemia. Fabomotizole also inhibits Giardia lamblia and has the potential to inhibit giardiasis. Fabomotizole also targets Sigma1R , NRH:quinone reductase 2 (NQO2) , and MAO-A to exert anxiolytic effects [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CM346. CAS No. 173352-21-1. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-14895. | |
| Fabomotizole hydrochloride | Fabomotizole (CM346) hydrochloride is a compound with anxiolytic and neuroprotective activities. Fabomotizole (CM346) hydrochloride also has activity against Giardia lamblia and has the potential to inhibit giardiasis. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CM346 hydrochloride. CAS No. 173352-39-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14895A. | |
| Factor D inhibitor 6 | Factor D inhibitor 6 is a potent, highly selective and orally active factor D (FD) inhibitor with an IC 50 of 30 nM and a K d of 6 nM. Factor D inhibitor 6 is inactive against factor B, lassical and lectin complement-pathway activation, and a broad assay panel of receptors, ion channels, kinases and proteases [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1386455-51-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122700. | |
| FAD-dependent glucose dehydrogenase | FAD-dependent glucose dehydrogenase (EC 1.1.5.9), or glucose dehydrogenase (FAD)/Pseudomonas glucose dehydrogenase. Glucose 1-dehydrogenase is an enzyme used as a regeneration cofactor to convert glucose and NAD(P) into NAD(P)H and gluconic acid [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FAD-GDH; Glucose 1-dehydrogenase. CAS No. 37250-84-3. Pack Sizes: 1 KU. Product ID: HY-E70014. | |
| Fadraciclib | Fadraciclib (CYC065) is a second-generation, orally available ATP-competitive inhibitor of CDK2 / CDK9 kinases [1] with IC 50 s of 5 and 26 nM, respectively [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CYC065. CAS No. 1070790-89-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101212. | |
| Falcarindiol | Falcarindiol, an orally active polyacetylenic oxylipin, activates PPARγ and increases the expression of the cholesterol transporter ABCA1 in cells. Falcarindiol induces apoptosis and autophagy. Falcarindiol has anti-inflammatory, antifungal, anticancer and antidiabetic properties [1] [2]. Falcarindiol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Natural products. CAS No. 55297-87-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N0364. | |
| Falcarinol | Falcarinol (Panaxynol) is a natural, orally active Hsp90 inhibitor targeting both the N-terminal and C-terminal of Hsp90 with limited toxicities. Falcarinol (Panaxynol) induces apoptosis [1]. Falcarinol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Natural products. Alternative Names: Panaxynol; Carotatoxin. CAS No. 21852-80-2. Pack Sizes: 1 mg (40.92 mM * 100 μL in Ethanol). Product ID: HY-N1455. | |
| Faldaprevir | Faldaprevir (BI 201335) is a potent, orally active and selective noncovalent inhibitor of NS3/4A protease of HCV (hepatitis C virus) genotypes 1a and 1b, with K i values of 2.6 and 2.0 nM, respectively. Faldaprevir inhibits HCV RNA replication, with EC 50 values of 6.5 and 3.1 nM, respectively. Faldaprevir has potent antiviral activity against chronic HCV infection [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BI 201335. CAS No. 801283-95-4. Pack Sizes: 1 mg. Product ID: HY-15256. | |
| Falecalcitriol | Falecalcitriol(Fulstan; Hornel) is an analog of calcitriol; has a higher potency both in vivo and in vitro systems, and longer duration of action in vivo. Uses: Scientific research. Group: Signaling pathways. CAS No. 83805-11-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-32342. | |
| Fallypride | Fallypride is a potent antagonist of dopamine D2/D3 receptor. Fallypride, in the form of fallypride ( 18 F), can be used as a positron emission tomography (PET) radiotracer [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 166173-78-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-135497. | |
| Faltan | Faltan is a dicarboximide fungicide , widely used on vines and several vegetable crops, and is also cytotoxic effect on human bronchial epithelial cells [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 133-07-3. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-B1878. | |
| FAM azide, 6-isomer | FAM azide, 6-isomer (6-FAM azide), a fluorescent dye, is a click chemistry reagent containing an azide group [1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: 6-FAM azide. CAS No. 1386385-76-7. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-D1314. | |
| Famciclovir | Famciclovir (BRL 42810) is an orally active nucleoside analogue. Famciclovir is an antiviral agent with potent activities against HBV, HSV and VZV. Famciclovir can be used for the research of herpesvirus infection [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BRL 42810. CAS No. 104227-87-4. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 500 mg. Product ID: HY-17426. | |
| Famitinib | Famitinib (SHR1020), an orally active multi-targeted kinase inhibitor, inhibits the activity of c-kit , VEGFR-2 and PDGFRβ with IC 50 values of 2.3 nM, 4.7 nM and 6.6 nM, respectively [1]. Famitinib exerts powerful antitumor activity in human gastric cancer cells and xenografts. Famitinib triggers apoptosis [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SHR1020. CAS No. 1044040-56-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108713. | |
| Famotidine | Famotidine (MK-208) is a competitive histamine H2-receptor antagonist. Its main pharmacodynamic effect is the inhibition of gastric secretion. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-208. CAS No. 76824-35-6. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-B0377. | |
| Famoxadone | Famoxadone (DPX-JE874) is a fungicide acting against a broad spectrum of fungi and is widely used in Integrated Pest Management strategies in different agricultural crops [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DPX-JE874. CAS No. 131807-57-3. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B2008. | |
| Famprofazone | Famprofazone is a non-steroidal anti-inflammatory drug (NSAID) that belongs to the pyrazolone series, and it has analgesic, anti-inflammatory, and antipyretic effects. Uses: Scientific research. Group: Signaling pathways. CAS No. 22881-35-2. Pack Sizes: 100 mg; 500 mg. Product ID: HY-B1054. | |
| Fanapanel | Fanapanel (ZK200775) is a highly selective AMPA/kainate antagonist with little activity against NMDA; have Ki values of 3.2 nM, 100 nM, and 8.5 μM against quisqualate, kainate, and NMDA, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ZK200775; MPQX. CAS No. 161605-73-8. Pack Sizes: 5 mg; 10 mg; 50 mg. Product ID: HY-15069. | |
| Fanapanel hydrate | Fanapanel hydrate (ZK200775 hydrate) is a highly selective AMPA/kainate antagonist with little activity against NMDA; have Ki values of 3.2 nM, 100 nM, and 8.5 μM against quisqualate, kainate, and NMDA, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ZK200775 hydrate; MPQX hydrate. CAS No. 1255517-78-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-15069A. | |
| Fantofarone | Fantofarone is a highly potent Calcium Channel antagonist. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SR 33557. CAS No. 114432-13-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-105117. | |
| FAPI-2 | FAPI-2 is a type of small molecule fibroblast activation protein inhibitor ( FAPI ) that targets the fibroblast activation protein (FAP) and has an inhibitory effect. This specific targeting ability makes FAPI-2 an effective tumor imaging agent, which can be used in cancer research. FAPI-2 can be used to synthesize 68Ga-FAPI-2 (a PET tracer) [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2370952-98-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128642. | |
| FAPI-74 | FAPI-74 is a PET (positron emission tomography) tracer targeting the fibroblast activation protein (FAP). FAPI-74 can be used for FAP-positive tumor research [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2374782-76-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-147173. | |
| Faralimomab | Faralimomab (64G12) is an immunomodulator, and a murine anti- IFNA1 IgG1 mAb [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: 64G12. CAS No. 167816-91-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99611. | |
| Farampator | Farampator (CX-691;Org24448) is an AMPA receptor positive modulator. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CX-691; Org24448. CAS No. 211735-76-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10937. | |
| Faricimab | Faricimab, an overall good safety and tolerability profile, is a bispecific antibody targeting Angiopoietin-2 ( Ang-2 ) and vascular endothelial growth factor-A ( VEGF-A ). Faricimab prevents retinal vascular leakage, cell death and inflammation in retinal ischemia/reperfusion (I/R) injury and sCNV mouse models. Faricimab demonstrates statistically superior visual acuity gains versus Ranibizumab (HY-P9951). Faricimab can be used for retinal diseases, such as age-related macular degeneration (w-AMD), diabetic macular edema (DME) and macular edema following retinal vein occlusion (RVO) [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: RG7716. CAS No. 1607793-29-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99116. | |
| Farletuzumab | Farletuzumab (MORAb-003) is a potent folate receptor-alpha (FRα) inhibitor. Farletuzumab is a humanized monoclonal antibody with high affinity for FR&alpha. Farletuzumab possesses growth-inhibitory functions on cells overexpressing FR&alpha. Farletuzumab can be used in research of cancer [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: MORAb-003. CAS No. 896723-44-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99153. | |
| Farletuzumab ecteribulin | Farletuzumab ecteribulin (MORAb-202) is an antibody-drug conjugate (ADC), consisting of the humanized anti-human folate receptor alpha (FRA) antibody Farletuzumab (HY-P99153) conjugated via reduced interchain disulfide bonds to Mal-PEG2-Val-Cit-PAB-eribulin. Farletuzumab ecteribulin has a agent-to-antibody ratio of 4.0. Farletuzumab ecteribulin is highly cytotoxic to FRA-positive cells in vitro. Farletuzumab ecteribulin has potent antitumor activity. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: MORAb-202. CAS No. 2407465-18-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99612. | |
| Farnesene (mixture of isomers) | Farnesene (mixture of isomers) is a farnesene with mixture of isomers. Farnesene is a herbivore-induced plant volatile (HIPV). Farnesene has an important effect on insect resistance in many plant species [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 125037-13-0. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 250 mg. Product ID: HY-14620A. | |
| Farnesol | Farnesol is a sesquiterpene alcohol that modulates cell-to-cell communication in Candida albicans , and has the activity in inhibiting bacteria. Uses: Scientific research. Group: Natural products. CAS No. 4602-84-0. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-Y0248A. | |
| Farnesyl pyrophosphate ammonium | Farnesyl pyrophosphate ammonium salt, a 15-carbon isoprenoid, is a metabolic intermediate of the mevalonate (MVA) pathway. Farnesyl pyrophosphate ammonium salt is a TRPM2 (TRP Channel) agonist, and activates TRPM2 opening for ion influx. Farnesyl pyrophosphate ammonium salt is a key branch substrate for cholesterol synthesis, ubiquinones synthesis, protein farnesylation decoration, and geranyl-geranyl pyrophosphate (GGPP) synthesis [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Farnesyl diphosphate ammonium. CAS No. 116057-57-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-113037C. | |
| Faropenem sodium | Faropenem sodium is an orally bioavailable penem antibiotic. Faropenem sodium regulates inorganic phosphate transporter Npt1. Faropenem sodium inhibits M. tuberculosis (MIC of 1.3 μg/mL) and B. anthracis [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 122547-49-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-76260. | |
| Fasedienol | Fasedienol (PH94B) is a neurochemical stimulator of the vomeronasal organ (VON). Fasedienol modulates the olfactory amygdala circuitry of fear and anxiety to alleviate symptoms of PMS and anxiety [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PH94B. CAS No. 23062-06-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145567. | |
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