MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Fingolimod hydrochloride | Fingolimod (FTY720) hydrochloride is a sphingosine 1-phosphate ( S1P ) antagonist with IC 50 of 0.033 nM in K562 and NK cells. Fingolimod hydrochloride is also a pak1 activator and immunosuppressant [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FTY720. CAS No. 162359-56-0. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg; 500 mg; 1 g; 5 g. Product ID: HY-12005. |  |
| Fingolimod phosphate | Fingolimod phosphate (FTY720 phosphate) is an orally active sphingosine 1-phosphate (S1P) receptor agonist. Fingolimod phosphate can promote the neuroprotective effects of microglia. Fingolimod phosphate can be used for the research of multiple sclerosis and neurologic diseases [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FTY720 phosphate. CAS No. 402615-91-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15381. | |
| Fingolimod (Standard) | Fingolimod (Standard) is the analytical standard of Fingolimod. This product is intended for research and analytical applications. Fingolimod (FTY720 free base) is a sphingosine 1-phosphate (S1P) antagonist with an IC 50 of 0.033 nM in K562 and NK cells. Fingolimod also is a pak1 activator, a immunosuppressant [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 162359-55-9. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-11063R. | |
| FINO2 | FINO2 is a potent ferroptosis inducer. FINO2 inhibits GPX4 activity. FINO2 is a stable oxidant that oxidizes ferrous iron and stable at varying pH levels. FINO2 causes widespread lipid peroxidation [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 869298-31-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-129457. | |
| Fipronil | Fipronil is a broad-spectrum insecticide effective against Lepidoptera species as well as thrips, locusts, ants, cockroaches, fleas and ticks. Fipronil selectively inhibits GABA receptor with IC 50 s of 30 nM and 1600 nM for cockroach and rat GABA receptors , respectively. Glutamate-gated chloride channels ( GluCls ), which are present in cockroaches but not in mammals, are sensitive to the blocking effect of Fipronil. Fipronil also induces apoptosis in HepG2 cells and promotes the expression of CYP1A1 and CYP3A4 mRNA in human hepatocytes [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 120068-37-3. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-B0822. | |
| Fipronil sulfone | Fipronil sulfone is the major metabolite of Fipronil.Fipronil sulfone selectively inhibits | |
| Firibastat | Firibastat (QGC001), an orally active brain penetrating proagent of EC33, is a first-in-class brain aminopeptidase A (APA) inhibitor ( K i =200 nM). Firibastat selectively and specifically inhibits conversion of brain angiotensin-II into angiotensin-III and decreases blood pressure in hypertensive rats [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: QGC001; RB150. CAS No. 648927-86-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109058. | |
| Firmonertinib | Firmonertinib (Alflutinib; Furmonertinib) is an orally active, mutant-selective, and highly brain penetrant EGFR inhibitor. Firmonertinib inhibits EGFR active mutations as well as the T790M acquired resistant mutation. Firmonertinib has the potential for the research of cancer diseases, especially advanced non-small cell lung cancer (NSCLC) with EGFR ex20ins mutation [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Alflutinib; Furmonertinib; AST2818. CAS No. 1869057-83-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-112870. | |
| Firmonertinib mesylate | Firmonertinib (Alflutinib; Furmonertinib) mesylate is is an orally active, mutant-selective, and highly brain penetrant EGFR inhibitor. Firmonertinib mesylate inhibits EGFR active mutations as well as the T790M acquired resistant mutation. Firmonertinib mesylate has the potential for the research of cancer diseases, especially advanced non-small cell lung cancer (NSCLC) with EGFR ex20ins mutation [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Alflutinib mesylate; Furmonertinib mesylate; AST2818 mesylate. CAS No. 2130958-55-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112870A. | |
| Firocoxib | Firocoxib (ML 1785713) is a potent, selective and orally active COX-2 inhibitor with an IC 50 of 0.13 μM. Firocoxib shows 58-fold more selective for COX-2 than COX-1 (IC 50 of 7.5 μM). Firocoxib has anti-inflammatory effects [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ML 1785713. CAS No. 189954-96-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-14670. | |
| Firsocostat | Firsocostat (ND-630; GS-0976; NDI-010976) is an acetyl-CoA carboxylase ( ACC ) inhibitor; inhibits human ACC1 and ACC2 with IC 50 values of 2.1 and 6.1 nM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ND-630; GS-0976; NDI-010976. CAS No. 1434635-54-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16901. | |
| Fisetin | Fisetin is a natural flavonol found in many fruits and vegetables with various benefits, such as antioxidant, anticancer, neuroprotection effects. Uses: Scientific research. Group: Natural products. CAS No. 528-48-3. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g. Product ID: HY-N0182. | |
| Fisetin (Standard) | Fisetin (Standard) is the analytical standard of Fisetin. This product is intended for research and analytical applications. Fisetin is a natural flavonol found in many fruits and vegetables with various benefits, such as antioxidant, anticancer, neuroprotection effects. Uses: Scientific research. Group: Natural products. CAS No. 528-48-3. Pack Sizes: 10 mg; 25 mg; 50 mg. Product ID: HY-N0182R. | |
| Fisogatinib | Fisogatinib (BLU-554) is a potent, highly selective and orally active fibroblast growth factor receptor 4 (FGFR4) inhibitor with an IC 50 of 5 nM. Fisogatinib has significant anti-tumor activity in models of hepatocellular carcinoma (HCC) that are dependent on FGFR4 signalling [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BLU-554. CAS No. 1707289-21-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100492. | |
| FITC | FITC (Fluorescein Isothiocyanate), is one of the green fluorescein derivatives widely used in biology. FITC has the characteristics of high absorptivity and excellent fluorescence quantum yield. The isothiocyanate group of FITC can be combined with amino, sulfhydryl, imidazole, tyrosyl, carbonyl and other groups on the protein, so as to achieve protein labeling including antibodies and lectins. In addition to its use as a protein marker, FITC can also be used as a fluorescent protein tracer to rapidly identify pathogens by labeling antibodies, or for microsequencing of proteins and peptides (HPLC). The maximum excitation wavelength of FITC is 494 nm. Once excited, it fluoresces yellow-green at a maximum emission wavelength of 520 nm. In addition, FITC is also a hapten that can induce contact hypersensitivity (CHS) and induce an atopic dermatitis model [1] [2] [3] [4]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: Fluorescein 5-isothiocyanate. CAS No. 3326-32-7. Pack Sizes: 100 mg; 500 mg. Product ID: HY-66019. | |
| FITM | FITM is a negative allosteric modulator of mGlu1 receptor with a K i of 2.5 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 932737-65-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101845. | |
| FL-411 | FL-411 is a potent and selective BRD4 inhibitor with an IC 50 of 0.43±0.09 μM for BRD4(1). Uses: Scientific research. Group: Signaling pathways. Alternative Names: BRD4-IN-1. CAS No. 2118944-88-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111102. | |
| FLAG peptide | FLAG peptide is a multifunctional fusion tag for the purification of recombinant proteins. FLAG peptide maintances the natural folding of its fusing proteins. FLAG peptide can be removed by enterokinase, and eluted under non-denaturing conditions [1]. Uses: Scientific research. Group: Peptides. CAS No. 98849-88-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P0223. | |
| Flavanone | Flavanone is a naturally occurring flavone. Flavanone has inhibitory activity for human estrogen synthetase ( aromatase ). Flavanone is the inhibitor for ERK/p38/NF-κB signaling pathway. Flavanone exhibits oral activity and antitumor efficacy [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 487-26-3. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-N7128. | |
| Flavin adenine dinucleotide | Flavin adenine dinucleotide (FAD) is a redox cofactor, more specifically a prosthetic group of a protein, involved in several important enzymatic reactions in metabolism. Uses: Scientific research. Group: Natural products. Alternative Names: FAD. CAS No. 146-14-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-B1654. | |
| Flavin adenine dinucleotide disodium salt | Flavin adenine dinucleotide (FAD) disodium salt is a redox cofactor, more specifically a prosthetic group of a protein, involved in several important enzymatic reactions in metabolism. Uses: Scientific research. Group: Natural products. Alternative Names: FAD disodium salt; FAD-Na2. CAS No. 84366-81-4. Pack Sizes: 10 mM * 1 mL; 25 mg. Product ID: HY-B1654A. | |
| Flaviviruses-IN-3 | Flaviviruses-IN-3 (compound 87) is a potent flaviviruse inhibitor. Flaviviruses-IN-3 reduces the WNV (West Nile virus) protease activity, with a inhibition of 54% [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 420090-97-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-153076. | |
| Flavokawain A | Flavokawain A, a proming anticarcinogenic agent , is a chalcone from kava extract with anti-tumor activity. Flavokawain A induces cell apoptosis by involvement of Bax protein-dependent and mitochondria-dependent apoptotic pathway. Flavokawain A has the potential for the study of bladder cancer [1]. Uses: Scientific research. Group: Natural products. CAS No. 3420-72-2. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-N2420. | |
| Flavokawain B | Flavokawain B (Flavokavain B) is an orally active chalcone. Flavokawain B results in activation of caspase-9, -3 and -8 , cleavage of PARP. Flavokawain B down-regulates Bcl-2 with concomitant increase in Bax level. Flavokawain B inhibits NF-κB , PI3K/Akt and MAPK signaling pathway. Flavokawain B exhibits Apoptotic effects. Flavokawain B inhibits MMP-9 and promotes ROS generation. Flavokawain B inhibits multiple tumors and inflammation [1] [2] [3] [4] [5] [6] [7] [8] [9] [10] [11] [12] [13]. Uses: Scientific research. Group: Natural products. Alternative Names: Flavokavain B. CAS No. 1775-97-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N2132. | |
| Flavone | Flavone is an endogenous metabolite. Uses: Scientific research. Group: Natural products. Alternative Names: 2-Phenyl-4-chromone. CAS No. 525-82-6. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-N2424. | |
| Flavonol | Flavonol is a cholinesterase ( ChE ) inhibitor, with an IC 50 value of 120 μM and a K i value of 74 μM. Flavonol has antioxidant, free radical-scavenging, antibacterial properties, and immune modulation functions. Flavonol inhibits the PriA helicase of Staphylococcus aureus. Flavonol can suppress the production of NO in LPS-activated RAW 264.7 cells by inhibiting the expression of the iNOS enzyme. Flavonol shows protective and analgesic effects in mice through various neuronal pathways. Flavonol can be used in research related to tumors and atherosclerosis diseases [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. CAS No. 577-85-5. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-107825. | |
| Flavopiridol | Flavopiridol (Alvocidib) is a broad spectrum and competitive inhibitor of CDKs , inhibiting CDK1, CDK2, CDK4 with IC 50 s of 30, 170, 100 nM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: HMR-1275; Alvocidib; L86-8275. CAS No. 146426-40-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10005. | |
| Flavopiridol Hydrochloride | Flavopiridol Hydrochloride (Alvocidib Hydrochloride) is a broad inhibitor of CDK , competing with ATP to inhibit CDKs including CDK1, CDK2, CDK4 with IC 50 s of 30, 170, 100 nM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Alvocidib Hydrochloride; L86-8275 Hydrochloride; HMR-1275 Hydrochloride. CAS No. 131740-09-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10006. | |
| Flavoxate hydrochloride | Flavoxate hydrochloride is a potent and competitive phosphodiesterase (PDE) inhibitor. Flavoxate hydrochloride is an antispasmodic agent and muscarinic mAChR antagonist. Flavoxate hydrochloride shows moderate calcium antagonistic activity and local anesthetic effect. Flavoxate hydrochloride can be used for the research of overactive bladder (OAB) and lower urinary tract infections [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Rec-7-0040; DW61. CAS No. 3717-88-2. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-B0549A. | |
| Flecainide | Flecainide is a potent and orally active antiarrhythmic agent. Flecainide blocks the cardiac fast inward Na + current (INa) and the rapid component of the delayed rectifier K + current. Flecainide prolongs the action potential duration (APD) in ventricular and atrial muscle fibres. Flecainide has the potential for the research of fetal tachycardias [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 54143-55-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-W010950. | |
| Flecainide acetate | Flecainide acetate (R-818) is a class 1C antiarrhythmic agent especially used for the management of supraventricular arrhythmia; works by blocking the Nav1.5 sodium channel in the heart, causing prolongation of the cardiac action potential. Uses: Scientific research. Group: Signaling pathways. Alternative Names: R-818. CAS No. 54143-56-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17429. | |
| Flecainide hydrochloride | Flecainide hydrochloride is a potent and orally active antiarrhythmic agent. Flecainide hydrochloride blocks the cardiac fast inward Na + current (INa) and the rapid component of the delayed rectifier K + current. Flecainide hydrochloride prolongs the action potential duration (APD) in ventricular and atrial muscle fibres. Flecainide hydrochloride has the potential for the research of fetal tachycardias [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 57415-44-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-W010950A. | |
| Fleroxacin | Fleroxacin (RO 23-6240) is a broad-spectrum antimicrobial fluoroquinolone. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RO 23-6240; AM-833. CAS No. 79660-72-3. Pack Sizes: 500 mg; 1 g; 5 g; 10 g. Product ID: HY-B0414. | |
| Flesinoxan | Flesinoxan is a hypotensive agent and a potent, high affinity and selective 5-hydroxytryptamine1A (5-HT1A) receptor agonist with an EC 50 value of 24 nM. Flesinoxan also has effective anxiolytic/antidepressant effects [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 98206-10-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-121653. | |
| Flibanserin | Flibanserin (BIMT-17; BIMT-17BS) is an orally active serotonin 5-HT1A receptor agonist and 5-HT2A receptor antagonist with K i values of 1 nM and 49 nM, respectively. Flibanserin binds to dopamine D4 receptors with an K i value of 4-24 nM. Flibanserin shows anti-depression and anti-anxiety effect, can be used to hypoactive sexual desire disorder (HSDD) research [1] - [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BIMT-17; BIMT-17BS. CAS No. 167933-07-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-A0095. | |
| FLLRN | FLLRN is a biological active peptide. (PAR1-specific antagonist peptide). Uses: Scientific research. Group: Peptides. Alternative Names: TRAP-6 (2-6). CAS No. 141136-84-7. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P5359. | |
| Flobetapir | Flobetapir (AV-45) may be a well-tolerated imaging agent. Flobetapir synthesizes Florbetapir (18F) that is a PET scanning radiopharmaceutical compound containing the radionuclide fluorine-18 [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AV-45. CAS No. 938435-69-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-129650. | |
| Flocoumafen | Flocoumafen (WL 108366) is an orally active vitamin K epoxide reductase inhibitor and a multi-target ligand, which includes prostaglandin F synthase, serum albumin, glucocorticoid receptor 2 , and MMP-9. Flocoumafen is a second-generation anticoagulant rodenticide (ARs) with a half-life of 177.4 hours and has deadly anticoagulant effects [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: WL 108366. CAS No. 90035-08-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-111186. | |
| Flomoxef sodium | Flomoxef sodium is a oxacephem group antibiotic, with excellent activity against various Gram-positive bacteria [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 92823-03-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-B0706A. | |
| Flonicamid | Flonicamid (IKI220) is a novel systemic insecticide with selective activity against hemipterous pests. The main insecticidal mechanism of flonicamid is starvation based on the inhibition of stylet penetration to plant tissues [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: IKI220. CAS No. 158062-67-0. Pack Sizes: 10 mM * 1 mL; 100 mg; 250 mg. Product ID: HY-119649. | |
| Flonoltinib | Flonoltinib is a potent and orally active dual JAK2/FLT3 inhibitor with IC 50 values of 0.7 nM, 4 nM, 26 nM and 39 nM for JAK2, FLT3, JAK1 and JAK3, respectively. Flonoltinib has anti-cancer activity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: JAK2/FLT3-IN-1. CAS No. 2387765-27-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-130247. | |
| Flonoltinib TFA | Flonoltinib TFA is a potent and orally active dual JAK2/FLT3 inhibitor with IC 50 values of 0.7 nM, 4 nM, 26 nM and 39 nM for JAK2, FLT3, JAK1 and JAK3, respectively. Flonoltinib TFA has anti-cancer activity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: JAK2/FLT3-IN-1 TFA. CAS No. 2928093-29-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-130247A. | |
| Flopropione | Flopropione is a 5-HT receptor antagonist and also a catechol-o-methyltransferase (COMT) inhibitor [1] [2]. Flopropione also as an antispasmodic agent [3]. Uses: Scientific research. Group: Natural products. CAS No. 2295-58-1. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-100562. | |
| Florfenicol | Florfenicol ((-)-Florfenicol) is an orally active broad-spectrum antibacterial antibiotic with anti-inflammatory, pro apoptotic, and immunomodulatory functions [6][7]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (-)-Florfenicol; SCH-25298. CAS No. 73231-34-2. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B1374. | |
| Florfenicol amine hydrochloride | Florfenicol amine hydrochloride is a metabolite of Florfenicol (HY-B1374). Florfenicol inhibits bacterial protein synthesis by binding to 50S and 70S subunits in the ribosome to abolish the activity of peptidyltransferase. Florfenicol, is a veterinary antibiotic, can be used in aquaculture to control susceptible bacterial diseases [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 108656-33-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-118099. | |
| Florfenicol-d3 | Florfenicol-d 3 is the deuterium labeled Florfenicol. Florfenicol, a commonly used veterinary antibiotic, is currently indicated for bovine respiratory disease, and also used in aquaculture for the control of enteric septicemia in catfish. Florfenicol can induce early embryonic death in eggs, with an LC50 of 1.07 μg/g. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: (-)-Florfenicol-d3; SCH-25298-d3. CAS No. 2213400-85-0. Pack Sizes: 1 mg. Product ID: HY-B1374S1. | |
| Florfenicol (Standard) | Florfenicol (Standard) is the analytical standard of Florfenicol. This product is intended for research and analytical applications. Florfenicol ((-)-Florfenicol) is an orally active broad-spectrum antibacterial antibiotic with anti-inflammatory, pro apoptotic, and immunomodulatory functions [6] [7]. Uses: Scientific research. Group: Signaling pathways. CAS No. 73231-34-2. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-B1374R. | |
| Flotetuzumab | Flotetuzumab (MGD006; S80880) is an investigational CD123/CD3 bispecific dual-affinity retargeting antibody ( DART ) molecule. Flotetuzumab reactivates T cells by simultaneously binding to CD123 in target cells and CD3 in effector T cells, leading to T-cell-mediated cytotoxicity in target cells. Flotetuzumab shows inhibitory effect on a mouse model of patient-derived xenograft (PDX) in acute myeloid leukemia (AML) [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: MGD006; S80880. CAS No. 1664355-28-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P99623. | |
| Floxuridine | Floxuridine (5-Fluorouracil 2'-deoxyriboside) is a pyrimidine analog and known as an oncology antimetabolite. Floxuridine inhibits Poly(ADP-Ribose) polymerase and induces DNA damage by activating the ATM and ATR checkpoint signaling pathways in vitro. Floxuridine is a extreamly potent inhibitor for S. aureus infection and induces cell apoptosis [1] [2]. Floxuridine has antiviral effects against HSV and CMV [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 5-Fluorouracil 2'-deoxyriboside. CAS No. 50-91-9. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg; 500 mg. Product ID: HY-B0097. | |
| FLT3-IN-17 | FLT3-IN-17 inhibits CYPs and FLT3 mutants activity ( IC 50 s: <0.5 nM for D835Y). FLT3-IN-17 is also a FAK inhibitor, with an IC 50 value of 12 nM. FLT3 ligand-2 can be used in the research of cancers [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2758999-62-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-148070. | |
| FLT3-IN-19 | FLT3-IN-19 (Comp 50) is a potent and selective FLT3 inhibitor with IC 50 of 0.213 nM. FLT3-IN-19 can be used in AML disease research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2237234-48-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-153473. | |
| FLT3-IN-2 | FLT3-IN-2 is a FLT3 inhibitor with IC50 of ? 1 μM, detailed information refer to WO 2012158957 A2 and WO 2007013896. Uses: Scientific research. Group: Signaling pathways. CAS No. 923562-23-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-18744. | |
| FLT3-IN-3 | FLT3-IN-3 is a potent FLT3 inhibitor with IC 50 s of 13 and 8 nM for FLT3 WT and FLT3 D835Y , respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 2229050-90-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112145. | |
| FLT3-IN-4 | FLT3-IN-4 is a potent and orally effective Fms-like tyrosine receptor kinase 3 ( FLT3 ; IC 50 =7 nM) inhibitor for treating acute myelogenous leukemia [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2304799-09-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128571. | |
| FLT3-IN-6 | FLT3-IN-6 is a potent and selective inhibitor of FLT3-ITD (FLT3 mutation) with an IC 50 of 1.336 nM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2377141-31-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128572. | |
| Fluanisone | Fluanisone has potent sedative effect in vivo. Fluanisone can be used to study schizophrenia [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1480-19-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-117699. | |
| Fluazifop-P-butyl | Fluazifop-P-butyl, a graminicide from arylophenoxypropionate group, is a acetyl-CoA carboxylase (ACCase) inhibitor [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 79241-46-6. Pack Sizes: 10 mM * 1 mL; 50 mg. Product ID: HY-B2007. | |
| Fluazinam | Fluazinam is a broad spectrum pyridinamine fungal inhibitor. Uses: Scientific research. Group: Signaling pathways. CAS No. 79622-59-6. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-B1839. | |
| Fluazinam (Standard) | Fluazinam (Standard) is the analytical standard of Fluazinam. This product is intended for research and analytical applications. Fluazinam is a broad spectrum pyridinamine fungal inhibitor. Uses: Scientific research. Group: Signaling pathways. CAS No. 79622-59-6. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1839R. | |
| Flubendazole | Flubendazole is an anthelmintic drug based on altering microtubule structure, inhibition of tubulin polymerization and disruption of microtubule function. Flubendazole induces apoptosis in human colorectal cancer (CRC) by blocking the STAT3 signaling axis and activation of autophagy. Flubendazole induces P53 expression and reduced Cyclin B1 and p-cdc2 expression. Flubendazole is an antitumor agent. Flubendazole can be used for worm and intestinal parasites [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 31430-15-6. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0294. | |
| Flucloxacillin sodium | Flucloxacillin sodium is an active antibiotic against gram-positive and gram-negative bacteria [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1847-24-1. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-A0246A. | |
| Fluconazole | Fluconazole (UK-49858) is a triazole antifungal agent with excellent activities against a broad range of fungi, especially against Candida albicans. Fluconazole inhibits C. albicans and Candida kefyr with IC 99 s range from 0.20 μg/mL to 0.39 μg/mL [1]. Uses: Scientific research. Group: Natural products. Alternative Names: UK-49858. CAS No. 86386-73-4. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0101. | |
| Flucytosine | Flucytosine (5-Fluorocytosine) is an antifungal compound with oral activity. Flucytosine is a widely used cytotoxic drug that, after further metabolism, produces fluorinated ribonucleotides and deoxyribonucleotides, inhibits DNA and protein synthesis, and has multiple effects such as inhibiting candida and candida neoplasm infection and producies cytotoxicity to cancer cells [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 5-Fluorocytosine; NSC 103805; Ro 2-9915. CAS No. 2022-85-7. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-B0139. | |
| Fludarabine | Fludarabine (NSC 118218) is a DNA synthesis inhibitor and a fluorinated purine analogue with antineoplastic activity in lymphoproliferative malignancies. Fludarabine inhibits the cytokine-induced activation of STAT1 and STAT1-dependent gene transcription in normal resting or activated lymphocytes [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: F-ara-A; NSC 118218. CAS No. 21679-14-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-B0069. | |
| Fludarabine-Cl | Fludarabine-Cl has an inhibitory effect on RNA adenosine deaminase 1 ( ADAR1 ) with an IC 50 of 0.87 μM and can be used to prevent and/or study cancer or tumor-related diseases [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2734853-80-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-145443. | |
| Fludarabine phosphate | Fludarabine (phosphate) is an analogue of adenosine and deoxyadenosine, which is able to compete with dATP for incorporation into DNA and inhibit DNA synthesis. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NSC 118218 phosphate. CAS No. 75607-67-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0028. | |
| Fludioxonil | Fludioxonil (CGA-173506) is a phenylpyrrole-type fungicide with oral activity that can inhibit the growth of S. sclerotiorum. Fludioxonil promotes tumor growth and metastasis, and induces cardiac toxicity. Fludioxonil causes cytoskeletal disruption, DNA damage, and apoptosis in mouse glioma cells [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CGA-173506. CAS No. 131341-86-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-W021040. | |
| Fludrocortisone | Fludrocortisone, a synthetic mineralocorticoid with anti-inflammatory activity. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 9α-Fludrocortisone; 9α-Fluorcortisol. CAS No. 127-31-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-B1203. | |
| Fludrocortisone acetate | Fludrocortisone acetate (9α-Fludrocortisone acetate) is an orally active synthetic mineralocorticoid. Fludrocortisone acetate can effectively control sodium retention. Fludrocortisone acetate is used in studies of cardiac injury, adrenal insufficiency and orthostatic hypotension [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 9α-Fludrocortisone acetate; 9α-Fluorcortisol acetate. CAS No. 514-36-3. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g. Product ID: HY-B1203A. | |
| Fluensulfone | Fluensulfone is a new nematicide for chemical control of plant parasitic nematodes. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MCW-2. CAS No. 318290-98-1. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-107771. | |
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