MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Fenticonazole Nitrate | Fenticonazole Nitrate is an antifungal imidazole ring derivative. Fenticonazole Nitrate operates via hindering ergosterol integration, and sequentially destructing the cytoplasmatic outer membrane. Fenticonazole Nitrate is effective against Gram-positive bacteria, mycoses, and vaginal candidiasis [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: REC 15-1476. CAS No. 73151-29-8. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0359. |  |
| Fentonium bromide | Fentonium bromide is an anti-ulcerogenic, anticholinergic and antispasmodic agent. Fentonium bromide can be used in the research of neurological conditions [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 5868-6-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122520. | |
| Fenvalerate | Fenvalerate is a potent protein phosphatase 2B (calcineurin) inhibitor with an IC 50 of 2-4 nM for PP2B-A&alpha. Fenvalerate is a pyrethroid ester insecticide and acaricide [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 51630-58-1. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-B2006. | |
| Feprazone | Feprazone (DA2370; Prenazone), an analogue of Phenylbutazone (HY-B0230), is a nonsteroidal anti-inflammatory agent with analgesic and antipyretic activities. Feprazone acts by inhibiting the activity of cyclooxygenase (COX)-2. Feprazone ameliorates free fatty acid (FFA)-induced oxidative stress by reducing the production of mitochondrial reactive oxygen species (ROS). Feprazone can decrease the expression of MMP-2 and MMP-9. Besides, Feprazone can suppress adipogenesis and increase lipolysis in differentiating 3 T3-L1 cells. Feprazone also can be used to research atherosclerosis and obesity [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DA2370; Prenazone; Zepelin. CAS No. 30748-29-9. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-114911. | |
| Ferric citrate | Ferric citrate (Iron(III) citrate), an orally active iron supplement, is an efficacious phosphate binder. Ferric citratee can be used for iron deficiency anemia and chronic kidney disease (CKD) research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Iron(III) citrate; Zerenex. CAS No. 3522-50-7. Pack Sizes: 100 mg. Product ID: HY-N1428C. | |
| Ferric citrate hydrate | Ferric citrate hydrate, an orally active iron supplement, is an efficacious phosphate binder. Ferric citrate hydrate can be used for iron deficiency anemia and chronic kidney disease (CKD) research [1]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 2338-5-8. Pack Sizes: 25 g; 50 g; 100 g. Product ID: HY-47030. | |
| Ferric maltol | Ferric maltol is an orally active monovalent iron (Fe 3+ ) complex. Ferric maltol is used in the study of iron deficiency anemia in inflammatory bowel disease [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 33725-54-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108017. | |
| Ferric pyrophosphate | Ferric pyrophosphate is a kind of biological materials or organic compounds that are widely used in life science research [1]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 10058-44-3. Pack Sizes: 25 g. Product ID: HY-B1648. | |
| Ferron | Ferron (8-Hydroxy-7-iodo-5-quinolinesulfonic acid) has antiseptic and antifungal activity. Ferron can prevent skin and mucosa bacterial irritations and inflammations [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 8-Hydroxy-7-iodo-5-quinolinesulfonic acid. CAS No. 547-91-1. Pack Sizes: 10 mM * 1 mL; 100 mg; 5 g. Product ID: HY-W103183. | |
| Ferroportin-IN-1 | Ferroportin-IN-1 is a ferroportin inhibitor extracted from patent WO2020123850A1 compound 23. Ferroportin-IN-1 can be used for the research of diseases caused by a lack of hepcidin or iron metabolism disorders [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2443432-65-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-145965. | |
| Ferroquine | Ferroquine (Ferrochloroquine), a ferrocenyl analogue of Chloroquine, is an antimalarial agent. Ferroquine shows parasiticidal effect on Plasmodium by inducing oxidative stress and the subsequent destruction of the membrane [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ferrochloroquine; SSR97193. CAS No. 185055-67-8. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19364. | |
| Ferrous bisglycinate | Ferrous bisglycinate is an orally active iron fortificants and therapeutic iron supplements. Ferrous bisglycinate can be used for the research of iron deficiency anemia [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 20150-34-9. Pack Sizes: 500 mg. Product ID: HY-130078. | |
| Fertirelin | Fertirelin is a GnRH and LH-RH analogue. Fertirelin can be used of the study for reversing cow follicular cysts [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 38234-21-8. Pack Sizes: 2 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-P0053. | |
| Ferulenol | Ferulenol, a sesquiterpene prenylated coumarin derivative, specifically inhibits succinate ubiquinone reductase at the level of the ubiquinonecycle. Ferulenol shows good antimycobacterial activity and haemorrhagic action [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 6805-34-1. Pack Sizes: 5 mg. Product ID: HY-129605. | |
| Ferulic acid | Ferulic acid is a novel fibroblast growth factor receptor 1 ( FGFR1 ) inhibitor with IC 50 s of 3.78 and 12.5 μM for FGFR1 and FGFR2 , respectively. Uses: Scientific research. Group: Natural products. Alternative Names: Coniferic acid. CAS No. 1135-24-6. Pack Sizes: 10 mM * 1 mL; 100 mg; 1 g; 5 g. Product ID: HY-N0060. | |
| Ferulic acid methyl ester | Ferulic acid methyl ester (Methyl ferulate) is a derivative of ferulic acid, isolated from Stemona tuberosa , with anti-inflammatory and antioxidant properties [1] [2]. Ferulic acid methyl ester is a cell membrane and brain permeable compound, shows free radical scavenging ability, used in the research of neurodegenerative disorders [1]. Ferulic acid methyl ester inhibits COX-2 expression, blocks p-p38 and p-JNK in primary bone marrow derived-macrophages [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Methyl ferulate. CAS No. 2309-7-1. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-W018643. | |
| Ferulic acid sodium | Ferulic acid sodium is a novel fibroblast growth factor receptor 1 ( FGFR1 ) inhibitor with IC 50 s of 3.78 and 12.5 μM for FGFR1 and FGFR2 , respectively. Uses: Scientific research. Group: Natural products. Alternative Names: Coniferic acid sodium. CAS No. 24276-84-4. Pack Sizes: 10 mM * 1 mL; 100 mg; 1 g; 5 g. Product ID: HY-N0060A. | |
| Ferutinin | Ferutinin, a natural terpenoid compound, is an estrogen receptor ERα agonist and estrogen ERβ-receptor agonist/antagonist with IC 50 s of 33.1 nM and 180.5 nM, respectively. Ferutinin acts as an electrogenic Ca 2+ -ionophore that increases calcium permeability of lipid bilayer membranes, mitochondria. Ferutinin possesses estrogenic, antitumor, antibacterial and antiinflammatory activities [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 41743-44-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-125703. | |
| Fesoterodine | Fesoterodine is an orally active, nonsubtype selective, competitive muscarinic receptor (mAChR) antagonist with pK i values of 8.0, 7.7, 7.4, 7.3, 7.5 for M1, M2, M3, M4, M5 receptors, respectively. Fesoterodine is used for the overactive bladder (OAB) [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 286930-02-7. Pack Sizes: 5 mg; 10 mg. Product ID: HY-70053. | |
| Fesoterodine fumarate | Fesoterodine Fumarate is an orally active, nonsubtype selective, competitive muscarinic receptor (mAChR) antagonist with pK i values of 8.0, 7.7, 7.4, 7.3, 7.5 for M1, M2, M3, M4, M5 receptors, respectively. Fesoterodine Fumarate is used for the overactive bladder (OAB) [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 286930-03-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-A0030. | |
| Fesoterodine L-mandelate | Fesoterodine L-mandelate is an orally active, nonsubtype selective, competitive muscarinic receptor (mAChR) antagonist with pK i values of 8.0, 7.7, 7.4, 7.3, 7.5 for M1, M2, M3, M4, M5 receptors, respectively. Fesoterodine L-mandelate is used for the overactive bladder (OAB) [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1206695-46-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-70053A. | |
| FeTMPyP | FeTMPyP is an orally active peroxynitrite (ONOO ) scavenger. FeTMPyP reduces nitrative stress and increases autophagy. FeTMPyP reduces PARP over-activation and neuroinflammation in chronic constriction injury (CCI)-induced rats, and ameliorates functional, behavioral and biochemical deficits [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 133314-07-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-120380. | |
| FeTPPS | FeTPPS, a 5,10,15,20-tetrakis (4-sulfonatophenyl) porphyrin iron III chloride peroxynitrite decomposition catalyst, possesses evident neuroprotective effects in a experimental model of spinal cord damage [1]. FeTPPS acts as a peroxynitrite scavenger and anti-nitrating agent in vivo. FeTPPS reduces nitric oxide ( NO ) production and apoptosis process [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 90384-82-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-131697. | |
| Fevipiprant | Fevipiprant (QAW039, NVP-QAW039) is s an orally active, selective, reversible prostaglandin D2 (DP2) receptor antagonist with an K d value of 1.14 nM. Fevipiprant has the potential for the research of bronchial asthma [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: QAW039; NVP-QAW039. CAS No. 872365-14-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16768. | |
| Fexaramine | Fexaramine is a potent and selective FXR agonist with an EC 50 of 25 nM. Fexaramine has no activity against hRXRα, hPPARαγδ, mPXR, hPXR, hLXRα, hTRβ, hRARβ, mCAR, mERRγ, and hVDR receptors [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 574013-66-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-10912. | |
| Fexinidazole | Fexinidazole (HOE 239) is an orally active, potent nitroimidazole antitrypanosomal agent. Fexinidazole shows trypanocidal activity against T. brucei subspecies and strains with IC 50 s of 0.7-3.3 μM (0.2-0.9 μg/ml). Fexinidazol has the potential for human sleeping sickness (HAT) caused by infection with T. brucei [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: HOE 239. CAS No. 59729-37-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13801. | |
| Fexofenadine | Fexofenadine (MDL-16455) is an orally active and nonsedative H1 receptor antagonist. Fexofenadine can be used in allergic rhinitis and chronic idiopathic urticarial research [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MDL-16455; Terfenadine carboxylate. CAS No. 83799-24-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0801. | |
| Fexofenadine hydrochloride | Fexofenadine (MDL-16455) hydrochloride is an orally active and nonsedative H 1 receptor antagonist. Fexofenadine hydrochloride can be used in allergic rhinitis and chronic idiopathic urticarial research [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MDL-16455 hydrochloride; Terfenadine carboxylate hydrochloride. CAS No. 153439-40-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0801A. | |
| Fezagepras | Fezagepras (Setogepram) acts as an orally active agonist for GPR40 and as an antagonist or inverse agonist for GPR84 [1]. Fezagepras decreases renal, liver and pancreatic fibrosis [1] [2]. Fezagepras exerts anti-fibrotic, anti-inflammatory and anti-proliferative actions [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Setogepram; PBI-4050. CAS No. 1002101-19-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100775A. | |
| Fezagepras sodium | Fezagepras (Setogepram) sodium acts as an orally active agonist for GPR40 and as an antagonist or inverse agonist for GPR84 [1]. Fezagepras sodium decreases renal, liver and pancreatic fibrosis [1] [2]. Fezagepras sodium exerts anti-fibrotic, anti-inflammatory and anti-proliferative actions [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Setogepram sodium; PBI-4050 sodium. CAS No. 1254472-97-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100775. | |
| Fezakinumab | Fezakinumab is an interleukin-22 (IL-22) monoclonal antibody. Fezakinumab can be used for the research of inflammatory disease, such as psoriasis and rheumatoid arthritis [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: ILV 094. CAS No. 1007106-86-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99244. | |
| Fezolinetant | Fezolinetant is an antagonist of the neurokinin 3 receptor (NK3R) , used for the treatment of menopausal hot flushes. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ESN-364. CAS No. 1629229-37-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19632. | |
| FFN511 | FFN511 is a potent fluorescent false neurotransmitters (FFNs) that targets neuronal vesicular monoamine transporter 2 (VMA T2). FFN511 inhibits serotonin binding to VMA T2 -containing membranes with an IC 50 of 1 μM. FFN511 directly images the dynamics of release during exocytosis, can be used to label dopamine terminals in live cortical-striatalacute slices [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1004548-96-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103465. | |
| FG-2216 | FG-2216 (IOX3) is a potent and orally active inhibitor of HIF prolyl hydroxylase-2 (PHD2) , with an IC 50 of 3.9 μM. FG-2216 induces robust erythropoietin and modest fetal hemoglobin in vivo [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: IOX3; YM311. CAS No. 223387-75-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15641. | |
| FG 7142 | FG 7142 (ZK 39106; LSU-65), a non-selectively benzodiazepine inverse agonist, has high affinity for the α1 subunit-containing GABAA receptor ( K i =91 nM). FG 7142 (ZK 39106; LSU-65) also modulates GABA-induced chloride flux at GABAA receptors expressing the α1 subunit ( EC 50 = 137 nM). FG 7142 (ZK 39106; LSU-65) can increase tyrosine hydroxylation and cause upregulation of β-adrenoceptors in mouse cerebral cortex [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ZK 39106; LSU-65. CAS No. 78538-74-6. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-100991. | |
| FGFR-IN-1 | FGFR-IN-1 is a potent FGFR inhibitor with an IC 50 of <100 nM for FGFR1, FGFR2, and FGFR3, respectively (patent US20130338134A1, example 219) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1513860-41-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145043. | |
| FGIN 1-27 | FGIN 1-27, an indoleacetamide, is a specific peripheral benzodiazepine receptor (PBR) ligand with a K i of 5.0 nM. FGIN 1-27 can penetrate the blood brain barrier (BBB). FGIN 1-27 inhibits the onset of Isoniazid-induced convulsions [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 142720-24-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101059. | |
| FH1 | FH1 (NSC 12407) enhances hepatocyte functions, and promotes the differentiation of induced pluripotent stem (iPS)-derived hepatocytes toward a phenotype more mature and the maturation of well-differentiated cultures of hepatocyte-like cells (iHeps) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NSC 12407; BRD-K4477. CAS No. 2719-5-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12346. | |
| FHD-609 | FHD-609 is a PROTAC degrader and inhibitor of BRD9 ( Bromodomain-containing protein 9 ). FHD-609 targets to ncBAF , can be used for research of wide range of cancers that contain a mutation in a BAF complex subunit. FHD-609 in combination with Telomelysin or INO5401, may play a role in adrenocortical carcinoma (ACC) treatment. (Blue: BRD9 ligand-6 (HY-49393), Black: linker (HY-168309); Pink: (S)-Deoxy-thalidomide-Br (HY-168308) ) [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2676211-64-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153367. | |
| FHT-2344 | FHT-2344 is a SMARCA4/SMARCA2 ATPase inhibitor with IC 50 values of 0.026 μM and 0.013 μM, respectively. FHT-2344 has anticancer activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2468058-90-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-149458. | |
| Fialuridine | Fialuridine is a nucleoside analog with antiviral activity [1]. Fialuridine shows anti-orthopoxvirus activity [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FIAU; DRG-0098; NSC 678514. CAS No. 69123-98-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-118122. | |
| Fianlimab | Fianlimab (REGN3767) is a human monoclonal antibody that targets the immune checkpoint receptor LAG-3 on T cells and has anti-tumour activity [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: REGN3767. CAS No. 2126132-98-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99617. | |
| Fiboflapon | Fiboflapon (GSK2190915; AM-803) is a potent and orally bioavailable 5-lipoxygenase-activating protein ( FLAP ) inhibitor with a potency of 2.9 nM in FLAP binding, an IC 50 of 76 nM for inhibition of LTB4 in human blood [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GSK2190915; AM-803. CAS No. 936350-00-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-15874. | |
| Fiboflapon sodium | Fiboflapon sodium (GSK2190915; AM-803) is a potent and orally bioavailable 5-lipoxygenase-activating protein ( FLAP ) inhibitor with a potency of 2.9 nM in FLAP binding, an IC 50 of 76 nM for inhibition of LTB4 in human blood [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GSK2190915 sodium salt; AM-803 sodium. CAS No. 1196070-26-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-15874A. | |
| Fibrin | Fibrin, isolated from bovine blood, is an insoluble protein produced in response to bleeding. Fibrin is the major component of the blood clot and is used for coagulation [1]. Uses: Scientific research. Group: Natural products. CAS No. 9001-31-4. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-B0665. | |
| Fibrinogen Binding Inhibitor Peptide | Fibrinogen Binding Inhibitor Peptide is a dodecapeptide (HHLGGAKQAGDV, H12), which is a fibrinogen γ-chain carboxy-terminal sequence (γ400-411). Fibrinogen Binding Inhibitor Peptide is a specific binding site of the ligand for activated glycoprotein (GP) IIb/IIIa. Uses: Scientific research. Group: Peptides. CAS No. 89105-94-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P1507. | |
| Fibrinogen-Binding Peptide | Fibrinogen-Binding Peptide (designed by anticomplementarity hypothesis) is a presumptive peptide mimic of the vitronectin binding site on the fibrinogen receptor. Fibrinogen-Binding Peptide binds fibrinogen and inhibits both the adhesion of platelets to fibrinogen and platelet aggregation, and also inhibits the adhesion of platelets to vitronectin [1]. Uses: Scientific research. Group: Peptides. CAS No. 137235-80-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P1741. | |
| Fibrinogen (Bovine) | Fibrinogen (Bovine) is a selective proteolytic molecule that can be activated by thrombin to assemble fibrin clots. Fibrinogen can regulate the activation of NF-KB in endothelial cells and upregulate the expression of inflammatory chemokines MCP-1 and MCP-1. Fibrinogen plays a key role in blood clotting, thrombosis, atherosclerosis and the pathological development of venous grafts, and can be used in the study of blood clotting and vascular diseases [1] [2] [3]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 9001-32-5. Pack Sizes: 50 mg; 100 mg. Product ID: HY-125864. | |
| Fibrinopeptide A, human TFA | Fibrinopeptide A, human TFA is a 16-residue short polypeptide cleaved from fibrinogen by thrombin. Fibrinopeptide A, human locates at the NH 2 -termini of the Aα chain [1]. Uses: Scientific research. Group: Peptides. Alternative Names: Human fibrinopeptide A TFA. CAS No. 61533-47-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P1538A. | |
| Fibronectin | Fibronectin, a glycoprotein present in blood as well as in cells, is a biomarker of tissue injury. Fibronectin binds to membrane-spanning receptor proteins called integrins. Fibronectin also binds to other extracellular matrix proteins such as collagen, fibrin, and heparan sulfate proteoglycans [1]. Uses: Scientific research. Group: Natural products. CAS No. 86088-83-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P3160. | |
| Ficain | Ficain is an enzyme extract composed of several proteases that can be isolated from Ficus hispida L. and the latex of fig ( Ficus carica ). Ficain has different specificities in different proportions during fruit ripening. Ficain is widely used in protein hydrolysis, food, production of bioactive peptides and antibody fragments [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ficin. CAS No. 9001-33-6. Pack Sizes: 1 g. Product ID: HY-P3028. | |
| Ficlatuzumab | Ficlatuzumab is a monoclonal antibody (McAb) targeting human hepatocyte growth factor ( HGF ). Ficlatuzumab blocks the activation of the HGF/c-Met signaling pathway, and inhibits c-Met receptor-mediated cancer cell proliferation, migration, and invasion [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 1174900-84-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99196. | |
| Ficonalkib | Ficonalkib is a potent inhibitor of Anaplastic lymphoma kinase (ALK) , the tyrosine kinase receptor. Ficonalkib, can be used as an antineoplastic agent [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2233574-95-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-152845. | |
| Fidarestat | Fidarestat (SNK 860) is an inhibitor of aldose reductase , with IC 50 s of 26 nM, 33 μM, and 1.8 μM for aldose reductase, AKR1B10 and V301L AKR1B10, respectively; Fidarestat (SNK 860) has the potential to treat diabetic disease. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SNK 860. CAS No. 136087-85-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-105185. | |
| Fidaxomicin | Fidaxomicin (OPT-80), a macrocyclic antibiotic , is an orally active and potent RNA polymerase inhibitor. Fidaxomicin has a narrow spectrum of antibacterial activity and a good anti- Clostridium difficile activity (MIC 90 =0.12?μg/mL). Fidaxomicin can be used for Clostridium difficile infection (CDI) research [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: OPT-80; PAR-101. CAS No. 873857-62-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17580. | |
| Fidrisertib | ALK2-IN-1 is a activin receptor-like kinase-2 ( ALK2 ) inhibitor extracted from patent WO2017181117A1, Compound 876, has an IC 50 of <10 nM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BLU-782; IPN-60130; ALK2-IN-1. CAS No. 2141955-96-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-117887. | |
| Figitumumab | Figitumumab (CP-751871) is a potent and fully human monoclonal anti - insulin-like growth factor 1 receptor ( IGF1R ) antibody. Figitumumab prevents IGF1 from binding to IGF1R with an IC 50 of 1.8 nM [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: CP-751871. CAS No. 943453-46-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99197. | |
| Filanesib | Filanesib (ARRY-520) is a selective and noncompetitive kinesin spindle protein ( KSP ) inhibitor, with an IC 50 of 6 nM for human KSP. Filanesib induces cell death by apoptosis in vitro. Filanesib has potent anti-proliferative activity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ARRY-520. CAS No. 885060-09-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15187. | |
| Filapixant | Filapixant is a purinoreceptor antagonist extracted from patent WO2016091776A1, example 348. Filapixant is the active reference substance of Eliapixant [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY 1902607. CAS No. 1948232-63-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109173. | |
| Filgotinib | Filgotinib (GLPG0634) is a selective, orally available JAK1 inhibitor with anti-inflammatory and antiviral activities. Filgotinib can effectively inhibit the activities of JAK1 , JAK2 , JAK3 and TYK2 with IC 50 values of 10 nM, 28 nM, 810 nM and 116 nM, respectively. Filgotinib also inhibits HIV-1 driven gene transcription and reduces proliferation of HIV-1 infected cells. Filgotinib can be used in the study of rheumatoid arthritis and inflammatory bowel disease [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GLPG0634. CAS No. 1206161-97-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18300. | |
| Filgotinib maleate | Filgotinib maleate (GLPG0634 maleate) is a selective, orally available JAK1 inhibitor with anti-inflammatory and antiviral activities. Filgotinib maleate can effectively inhibit the activities of JAK1 , JAK2 , JAK3 and TYK2 with IC 50 values ??of 10 nM, 28 nM, 810 nM and 116 nM, respectively. Filgotinib maleate also inhibits HIV-1 driven gene transcription and reduces proliferation of HIV-1 infected cells. Filgotinib maleate can be used in the study of rheumatoid arthritis and inflammatory bowel disease [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GLPG0634 maleate. CAS No. 1802998-75-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18300A. | |
| Filipin III | Filipin III is the major component of Filipin, a 28-membered ring pentaene macrolide antifungal antibiotic produced by S. filipinensis , S. avermitilis and S. miharaensis. Filipin interacts with membrane sterols causing the alteration of membrane structure [1]. Uses: Scientific research. Group: Natural products. CAS No. 480-49-9. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N6718. | |
| Fimasartan | Fimasartan (BRA-657) is an orally effective angiotensin receptor AT1 non-peptide antagonist. Fimasartan has antihypertensive effects. Fimasartan improves neuroinflammation and brain injury mediated by NLRP3 inflammatome after intracerebral hemorrhage, and has neuroprotective effect. Fimasartan inhibits the expression of inducible nitric oxide synthase through the inactivation of NF-κB and activator protein-1 [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BR-A-657. CAS No. 247257-48-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0780. | |
| Fimepinostat | Fimepinostat (CUDC-907) potently inhibits class I PI3K s as well as classes I and II HDAC enzymes with an IC 50 of 19/54/39 nM and 1.7/5.0/1.8/2.8 nM for PI3Kα/PI3Kβ/PI3Kδ and HDAC1/HDAC2/HDAC3/HDAC10 , respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CUDC-907. CAS No. 1339928-25-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13522. | |
| Finafloxacin | Finafloxacin is a fluoroquinolone antimicrobial agent that exhibits optimum efficacy in slightly acidic environments. Uses: Scientific research. Group: Signaling pathways. CAS No. 209342-40-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13451. | |
| Finasteride | Finasteride (MK-906) is an orally active and competitive 5α-reductase inhibitor, with an IC 50 of 4.2 nM for type II 5α-reductase. Finasteride has approximately a 100-fold greater affinity for type II 5α-reductase enzyme than for the type I enzyme. Finasteride can be used for the research of benign prostatic hyperplasia (BPH) and androgenic alopecia [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-906. CAS No. 98319-26-7. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg. Product ID: HY-13635. | |
| Finerenone | Finerenone (BAY 94-8862) is a third-generation, selective, and orally available nonsteroidal mineralocorticoid receptor (MR) antagonist ( IC 50=18 nM). Finerenone displays excellent selectivity versus glucocorticoid receptor (GR), androgen receptor (AR), and progesterone receptor (>500-fold). Finerenone has the potential for cardiorenal diseases research, such as type 2 diabetes mellitus and chronic kidney disease [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY 94-8862. CAS No. 1050477-31-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111372. | |
| Fingolimod | Fingolimod (FTY720 free base) is a sphingosine 1-phosphate ( S1P ) antagonist with an IC 50 of 0.033 nM in K562 and NK cells. Fingolimod also is a pak1 activator, a immunosuppressant [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FTY720 free base. CAS No. 162359-55-9. Pack Sizes: 100 mg; 200 mg; 500 mg; 1 g; 5 g. Product ID: HY-11063. | |
| Fingolimod-d4 | Fingolimod-d 4 is the deuterium labeled Fingolimod. Fingolimod (FTY720 free base) is a sphingosine 1-phosphate (S1P) antagonist with an IC50 of 0.033 nM in K562 and NK cells. Fingolimod also is a pak1 activator, a immunosuppressant[1]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: FTY720 free based-d4. CAS No. 1346747-38-3. Pack Sizes: 500 μg; 1 mg. Product ID: HY-11063S. | |
| Fingolimod-d4 hydrochloride | Fingolimod-d 4 (hydrochloride) is the deuterium labeled Fingolimod hydrochloride. Fingolimod hydrochloride (FTY720) is a sphingosine 1-phosphate (S1P) antagonist with an IC50 of 0.033 nM in K562 and NK cells. Fingolimod hydrochloride (FTY720) also is a pak1 activator, a immunosuppressant[1]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: FTY720-d4. CAS No. 1346604-90-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-11063S1. | |
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