MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
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Drozitumab
Drozitumab (PRO 95780) is a human agonistic monoclonal antibody which binds the death receptor DR5. Drozitumab has potent antitumor activity against rhabdomyosarcoma [1] [2] [3]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: PRO 95780; rhuMAb-DR 5; Anti-Human DR5 Recombinant Antibody. CAS No. 912628-39-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99286.
DRP1i27 dihydrochloride
DRP1i27 dihydrochloride is a potent inhibitor of human Drp1 (dynamin-related protein 1). DRP1i27 dihydrochloride binds to the GTPase site of Drp1, with hydrogen bonds to Gln34 and Asp218. DRP1i27 dihydrochloride targets Drp1-mediated mitochondrial fission in cell line models and protects against simulated ischemia-reperfusion injury[1]. Uses: Scientific research. Group: Signaling pathways. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-152086A.
Drpitor1a
Drpitor1a is a potent Drp1 inhibitor. Drpitor1a inhibits mitochondrial ROS production, preventes mitochondrial fission, and improves right ventricular diastolic dysfunction during IR (ischemia reperfusion) injury. Drpitor1a has the potential for the research of lung cancer[1]
DS12881479
DS12881479 is a potent and selective Mnk1 inhibitor with an IC 50 value of 21 nM. DS12881479 can be used in cancer research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2373065-59-7. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-148105.
DS18561882
DS18561882 is a highly potent, isozyme-selective methylenetetrahydrofolate dehydrogenase 2 (MTHFD2) inhibitor with an IC50 value of 0.0063 ?M. DS18561882 also has inhibitory effect on MTHFD1 (IC50=0.57 ?M). DS18561882 exhibits a good oral pharmacokinetic profile[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2227149-22-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-130251.
DS2
DS2 is a selective positive allosteric modulator of δ-GABA A receptor. DS2 selectively potentiates GABA responses mediated by α4β3δ receptor. DS2 does not enhance activity at α4β3γ2 and α1β3γ2 receptors. DS2 relieves pain and has the potential for sleep disorders research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 374084-31-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-103520.
DS69910557
DS69910557 is a potent, selective and orally activehuman parathyroid hormone receptor 1 (hPTHR1) antagonist. DS69910557 has antagonistic activity for PTHR1 with an IC50 value of 0.08 ?M. DS69910557 can be used for the research of hyperparathyroidism, hypercalcemia of malignancy and osteoporosis[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3032750-17-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-148350.
D-Saccharic acid 1,4-lactone hydrate
D-Saccharic acid 1,4-lactone hydrate is an orally active β-glucuronidase inhibitor ( IC 50 =48.4 μM). D-Saccharic acid 1,4-lactone hydrate can be used as a standard agent compared with novel β-glucuronidase inhibitors. D-Saccharic acid 1,4-lactone hydrate possesses anticarcinogenic, detoxifying, and antioxidant properties [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 61278-30-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-134453A.
D-Serine
D-Serine ((R)-Serine), an endogenous amino acid involved in glia-synapse interactions that has unique neurotransmitter characteristics, is a potent co-agonist at the NMDA glutamate receptor. D-Serinee has a cardinal modulatory role in major NMDAR-dependent processes including NMDAR-mediated neurotransmission, neurotoxicity, synaptic plasticity, and cell migration [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: (R)-Serine. CAS No. 312-84-5. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-100808.
DSG Crosslinker
DSG Crosslinker is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Disuccinimidyl glutarate. CAS No. 79642-50-5. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-114697.
DSM265
DSM265 is a long-duration inhibitor of P. falciparum dihydroorotate dehydrogenase ( Pf DHODH ) with an IC 50 of 8.9 nM. DSM265 can also inhibit the growth of Pf 3D7 parasites with an EC 50 of 4.3 nM [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1282041-94-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-100184.
D-Sorbitol
D-Sorbitol (Sorbitol) is a six-carbon sugar alcohol and can used as a sugar substitute. D-Sorbitol can be used as a stabilizing excipient and/or isotonicity agent, sweetener, humectant, thickener and dietary supplement [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Sorbitol; D-Glucitol. CAS No. 50-70-4. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-B0400.
D-Sorbitol, for cell culture
D-Sorbitol, for cell culture (D-Glucitol, for cell culture) is a biochemical reagent that can be used as a biological material or organic compound for life science related research [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: D-Glucitol, for cell culture. CAS No. 50-70-4. Pack Sizes: 25 g. Product ID: HY-B0400B.
D-(+)-Sorbose
D-(+)-Sorbose, an active enantiomer of D-Sorbose, which inhibits disaccharidase activity and demonstrates suppressive action on postprandial blood levels of glucose and insulin in the rat. D-sorbose acts as a sweetener may contribute to the prevention of lifestyle-related diseases, such as type 2 diabetes mellitus [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3615-56-3. Pack Sizes: 10 mg. Product ID: HY-W145497.
DSP-4 hydrochloride
DSP-4 hydrochloride is a highly and selective adrenergic neurotoxin. DSP-4 hydrochloride can cross the blood brain barrier. DSP-4 hydrochloride can be used for the temporary selective degradation of the central and peripheral noradrenergic neurons [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Neurotoxin DSP 4 hydrochloride. CAS No. 40616-75-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-103210.
DSPC
DSPC (1,2-Distearoyl-sn-glycero-3-phosphorylcholine) is a cylindrical-shaped lipid. DSPC is used to synthesize liposomes, and is the lipid component in the lipid nanoparticle (LNP) system [1] [2]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: 1,2-Distearoyl-sn-glycero-3-PC; 1,2-Distearoyl-sn-glycero-3-phosphorylcholine. CAS No. 816-94-4. Pack Sizes: 100 mg; 500 mg. Product ID: HY-W040193.
DSP Crosslinker
DSP Crosslinker is a cleavable ADC linker, used in the synthesis of antibody-drug conjugates (ADCs)[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 57757-57-0. Pack Sizes: 100 mg; 250 mg; 500 mg. Product ID: HY-118759.
DSPE-Biotin
DSPE-Biotin is a lipid. DSPE-Biotin can be used for the research of various biochemical [1]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 133695-76-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W441000.
DSPE-Mal
DSPE-MAL is a phospholipid compound with a maleimide reactive group. DSPE-MAL contains two saturated fatty acids and can self-assemble in water to form a lipid bilayer. DSPE-MAL can be used to prepare liposomes as nanocarriers for active molecules[1]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 1360858-99-6. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-W441007.
DSPE-NHS
DSPE-NHS is a bioconjugation phospholipid molecule with two hydrophobic lipid tails. DSPE-NHS is a self-assembling reagent which forms lipid bilayer in aqueous solution. The NHS-ester is reactive with N-terminal of protein/peptide or other amine molecule to form a stable amide linkage. DSPE-NHS labels antibodies. DSPE-NHS can be used to prepare liposomes as agent nanocarrier[1]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 1383932-86-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W441011.
DSPE-PEG 2000
DSPE-PEG 2000 is a PEG polymer containing DSPE and amine end groups. DSPE-PEG 2000 can be used to form micelles as nanoparticles for drug delivery[1][2]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 892144-24-0. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-142979.
DSPE-PEG2000-Mal ammonium
DSPE-PEG-Maleimide has DSPE phospholipid and maleimide to prepare nanostructured lipid carrier. DSPE-PEG-Maleimide extends blood circulation time and higher stability for encapsulated agents [1] [2]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: DSPE-PEG2000 Maleimide ammonium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[maleimide(polyethylene glycol)-2000] ammonium. CAS No. 474922-22-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-144004.
DSPE-PEG2000-Maleimide
DSPE-PEG2000-Maleimide is a phospholipid-PEG conjugate. DSPE-PEG2000-Maleimide utilizes the amphiphilicity of DSPE to insert into the lipid bilayer of liposomes or nanoparticles. DSPE-PEG2000-Maleimide covalently couples to the sulfhydryl (-SH) of ligands (such as antibodies, peptides, or proteins) via thiol-maleimide click chemistry, giving the particles targeting capabilities. DSPE-PEG2000-Maleimide can be used in the researches of breast cancer, lymphoma, and inherited retinal degeneration[1][2][3][4]. Uses: Scientific research. Group: Biochemical assay reagents. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-140739.
DSPE-PEG5000-Mal ammonium
DSPE-PEG-Maleimide has DSPE phospholipid and maleimide to prepare nanostructured lipid carrier. DSPE-PEG-Maleimide extends blood circulation time and higher stability for encapsulated agents [1] [2]. DSPE-PEG5000-Mal ammonium contains PEG5000. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: DSPE-PEG5000 Maleimide ammonium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[maleimide(polyethylene glycol)-5000] ammonium. CAS No. 474922-22-0. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-144004A.
DSPE-PEG-Amine, MW 2000 ammonium
DSPE-PEG-Amine, MW 2000 (ammonium), an amine derivative of phospholipid poly ethylene glycol, is used in the synthesis of solid lipid and thermosensitive liposomal nanoparticles for the delivery of anticancer agents [1] [2] [3]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: DSPE-PEG-NH2, MW 2000 ammonium; DSPE-PEG(2000) Amine ammonium. CAS No. 474922-26-4. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-125924.
DSPE-PEG-Biotin, MW 2000
DSPE-PEG-Biotin, MW 2000 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: DSPE-PEG(2000) Biotin. CAS No. 385437-57-0. Pack Sizes: 50 mg; 100 mg. Product ID: HY-140736.
DSPE-PEG Carboxylic acid (sodium), MW 2000
DSPE-PEG Carboxylic acid (sodium), MW 2000 is a PEG-lipid that can be used in the preparation of drug delivery nanoparticles[1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: DSPE PEG(2000) Carboxylic Acid sodium. CAS No. 1403744-37-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-141892A.
DSPE-PEG-DBCO ammonium
DSPE-PEG-DBCO ammonium is the ammonium salt form of DSPE-PEG-DBCO. DSPE-PEG-DBCO ammonium is utilized in copper-free click chemistry through SPAAC conjugation with an azido-functionalized peptide ligand. DSPE-PEG-DBCO ammonium is applied in drug-delivery and nanoparticle research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2052955-83-4. Pack Sizes: 1 mg; 5 mg. Product ID: HY-155788.
DSPE-PEG-DBCO, MW 2000
DSPE-PEG-DBCO, MW 2000 is a phospholipid-PEG polymer that can be used to form micelles as lipid nanoparticles for drug delivery[1]. DSPE-PEG-DBCO, MW 2000 is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: DSPE-PEG(2000)-DBCO. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-W440835.
DSPE-PEG-Folate, MW 2000
DSPE-PEG-Folate, MW 2000 is a PEG derivative containing folic acid. DSPE-PEG-Folate, MW 2000 has a targeting effect and bind to folate receptors in cancer cells. DSPE-PEG-Folate, MW 2000 form micelles/lipid bilayer and can be used to targeted drug delivery system research. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: DSPE-PEG(2000) Folate. Pack Sizes: 5 mg; 10 mg. Product ID: HY-W440888.
DSPE-PEG-Folate, MW 5000
DSPE-PEG-Folate, MW 5000 is a PEG derivative containing folic acid. DSPE-PEG-Folate, MW 5000 has a targeting effect and bind to folate receptors in cancer cells. DSPE-PEG-Folate, MW 5000 form micelles/lipid bilayer and can be used to targeted drug delivery system research[1][2]. Uses: Scientific research. Group: Biochemical assay reagents. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W440890.
DSPE-PEG-Maleimide (MW 2000)
DSPE-PEG-Maleimide (MW 2000) is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DSPE-PEG-Maleimide (MW 2000)can be used in drug delivery research[1]. Uses: Scientific research. Group: Biochemical assay reagents. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-166648.
DSPE-PEG-Maleimide, MW 5000
DSPE-PEG-Maleimide, MW 5000 has DSPE phospholipid and maleimide to prepare nanostructured lipid carrier. DSPE-PEG-maleimide extends blood circulation time and higher stability for encapsulated agents[1][2]. Uses: Scientific research. Group: Biochemical assay reagents. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-140740.
DSPE-PEG-NHS, MW 2000
DSPE-PEG-NHS, MW 2000 is a PEG-modified phospholipid derivative that can be used to prepare liposomes. DSPE-PEG-NHS, MW 2000 is commonly employed as a linker molecule for the surface modification of liposomes to confer targeting capabilities. DSPE-PEG-NHS, MW 2000 can be used in the study of drug delivery[1][2]. Uses: Scientific research. Group: Biochemical assay reagents. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-W441014.
DSPE-PEG-SH, MW 2000
DSPE-PEG-SH, MW 2000 is a pegylated phospholipid with thiol group which is reactive with maleimide to form a covalent thioether linkage. The amphiphatic polymer can form lipid bilayer in aqueous solution and be used to encapsulate agents for drug delivery system, such as mRNA vaccine. Uses: Scientific research. Group: Biochemical assay reagents. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-W440896.
DSRM-3716
DSRM-3716 (5-Iodoisoquinoline) is a potent and selective SARM1 NADase inhibitor with an IC50 of 75 nM. DSRM-3716 is selective against other NAD+-processing enzymes, receptors, and transporters. DSRM-3716 provides robust axon protection[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 5-Iodoisoquinoline. CAS No. 58142-99-7. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-W021879.
DT-061
DT-061 is an orally bioavailable activator of protein phosphatase 2A (PP2A) and could be applied in the therapy of KRAS-mutant and MYC-driven tumorigenesis[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1809427-19-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112929.
DT-2
DT-2 is a potent and selective inhibitor of the cGMP-dependent protein kinase ( PKG ). DT-2 inhibits PKG catalyzed phosphorylation (K i : 12.5 nM) [1]. Uses: Scientific research. Group: Peptides. CAS No. 1220985-78-3. Pack Sizes: 1 mg. Product ID: HY-P2692A.
DT2216
DT2216 is a potent and selective BCL-XL ( Bcl-2 family member) degrader based on PROTAC technology. DT2216 causes effective degradation of BCL-XL protein by recruiting Von Hippel-Lindau (VHL) E3 ubiquitin ligase. DT2216 inhibits various BCL-XL-dependent leukemia and cancer cells but considerably less toxic to platelets. DT2216 is composed of the Bcl-2 family protein inhibitor Navitoclax (HY-10087), a linker, and a VHL E3 ubiquitin ligase (Red: Navitoclax; Blue: VHL ligand; Black: linker) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2365172-42-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-130604.
DT-6
DT-6 is an effective TGF-β1 inhibitor. DT-6 inhibits M2 macrophage induced epithelial to mesenchymal transition and invasive migration of cancer cells. DT-6 can be used for cancer diseases research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2414315-95-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-156512.
DTA
DTA (2,4-Disulfamyl-5-trifluoromethylaniline) is a cyclic AMP phosphodiesterase inhibitor that binds to erythrocyte carbonic anhydrase [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 2,4-Disulfamyl-5-trifluoromethylaniline. CAS No. 654-62-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W011293.
dTAG-13-NEG
dTAG-13-NEG is a negative control of dTAG-13. dTAG-13 (HY-114421), a PROTAC-based heterobifunctional degrader, is a selective degrader of FKBP12F36V with expression of FKBP12F36V in-frame with a protein of interest[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2451573-90-1. Pack Sizes: 5 mg; 10 mg. Product ID: HY-161157.
dTAG-47
dTAG-47, heterobifunctional dTAG molecule, targets mutant FKBP12 (FKBP12F36V). FKBP12F36V serves as a degradation tag (dTAG) and is fused to a protein of interest. dTAG-47 can be used for the research of basal-like breast cancers (BBC)[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2265886-81-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-147098.
D-Tagatose
D-Tagatose (D-(-)-Tagatose) is a rare monosaccharide found in nature with prebiotic characteristics. D-Tagatose is as a substitute for sucrose and a low-calorie sweetener in foodstuffs such as gum, fruit juice, and beverages. D-Tagatose is also a potential antidiabetic agent for the research of type II diabetes and a prebiotic to help elevate beneficial bacteria in the colon, prevent colon cancer, and lower cholesterol [1]. Uses: Scientific research. Group: Natural products. Alternative Names: D-(-)-Tagatose. CAS No. 87-81-0. Pack Sizes: 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-42680.
dTAGV-1 hydrochloride
dTAGV-1 hydrochloride is the hydrochloride form of dTAGV-1 that is a small molecule degrader of FKBP12 [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2624313-16-0. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-145514C.
dTAGV-1-NEG
dTAGV-1-NEG is a diastereomer and as a heterobifunctional negative control of dTAGV-1. dTAGV-1 is an FKBP12F36V-selective degrader[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2451573-87-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-145514A.
dTAGV-1 TFA
dTAGV-1 TFA is a potent and selective degrader of mutant FKBP12 F36V fusion proteins. dTAGV-1 TFA can induce degradation of FKBP12 F36V -Nluc in vivo [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2624313-15-9. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-145514.
D-Tartaric acid
D-Tartaric acid (D-(-)-Tartaric acid) is a kind of biological materials or organic compounds that are widely used in life science research [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: D-(-)-Tartaric acid. CAS No. 147-71-7. Pack Sizes: 10 g; 50 g. Product ID: HY-Y1134.
DTE
DTE (Dithioerythritol) is a sulfur-containing sugar derived from the corresponding 4-carbon monosaccharide erythrose; an epimer of dithiothreitol (DTT). DTE is a thiol reducing agent [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Dithioerythritol; Clelands reagent. CAS No. 6892-68-8. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-15916.
D-Tetramannuronic acid
D-Tetramannuronic acid, an alginate oligomer, is produced by marine brown algae and by a limited range of Gram negative bacteria. D-Tetramannuronic acid can be used for the research of pain and vascular dementia [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. CAS No. 149511-34-2. Pack Sizes: 1 mg. Product ID: HY-N7699B.
DTHIB
DTHIB is a direct and selective heat shock factor 1 (HSF1) inhibitor with a Kd of 160 nM for DTHIB binding to the HSF1 DNA binding domain (DBD). DTHIB inhibits HSF1 cancer gene signature (HSF1 CaSig) and selectively stimulates degradation of nuclear HSF1. DTHIB has potently anticancer activities and can be used for prostate cancer research[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 897326-30-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-138280.
D-Threitol
D-threitol serves as a antifreeze agent in the Alaskan beetle Upis ceramboides. Uses: Scientific research. Group: Natural products. CAS No. 2418-52-2. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-W012846.
D-Threonine
D-Threonine (H-D-Thr-OH) is an enantiomer of L-threonine. D-Threonine is a metabolite of Saccharomyces cerevisiae. Uses: Scientific research. Group: Natural products. Alternative Names: H-D-Thr-OH. CAS No. 632-20-2. Pack Sizes: 500 mg. Product ID: HY-W012874.
D-threo-PDMP hydrochloride
D-threo-PDMP hydrochloride is a glucosylceramide (GlcCer) synthase inhibitor that inhibits glucosylceramide (GlcCer) and lactosylceramide (LacCer) levels in B16 melanoma cells. D-threo-PDMP hydrochloride lacks reactivity to the other two surface antigens anti-melanoma monoclonal antibodies M562 and M622 and the major histocompatibility antigen anti-H-2KbDb monoclonal antibody, so it is specific for B16 melanoma sex [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 139889-62-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-116392F.
D-Thyroxine
D-Thyroxine (D-T4) is an orally active thyroid hormone that inhibits the secretion of TSH. D-Thyroxine can inhibit goiter, promote metamorphosis of tadpoles and influence cholesterol metabolism. D-Thyroxine can be used for the study of hypercholesterolemia [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: D-T4. CAS No. 51-49-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-A0152.
DTME
DTME is a deoxyribozyme. DTME can effectively catalyze the Diels-Alder reaction [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 71865-37-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W106411.
DTNB
DTNB (Ellmans Reagent) is a chemical used to quantify the number or concentration of thiol groups [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Ellmans Reagent. CAS No. 69-78-3. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-15915.
DTP3
DTP3 TFA is a potent and selective GADD45β/MKK7 inhibitor. DTP3 TFA targets an essential, cancer-selective cell-survival module downstream of the NF-κB pathway [1]. Uses: Scientific research. Group: Peptides. CAS No. 1809784-29-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100538.
DTP3 TFA
DTP3 TFA is a potent and selective GADD45β/MKK7 (growth arrest and DNA-damage-inducible β/mitogen-activated protein kinase kinase 7) inhibitor. DTP3 TFA targets an essential, cancer-selective cell-survival module downstream of the NF-κB pathway [1]. Uses: Scientific research. Group: Peptides. CAS No. 2759216-46-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100538A.
D-(+)-Trehalose
D-(+)-Trehalose (α,α-Trehalose) is an orally active disaccharide, showing anti-desiccant and cryopreservative activities. D-(+)-Trehalose acts as an osmolyte, and stress protectant and helps in the storage and transport of carbon. D-(+)-Trehalose can be used as a food ingredient and pharmaceutical excipient [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: D-Trehalose; α,α-Trehalose. CAS No. 99-20-7. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-N1132.
D-(+)-Trehalose dihydrate
D-(+)-Trehalose dihydrate, isolated from Saccharomyces cerevisiae , can be used as a food ingredient and pharmaceutical excipient. Uses: Scientific research. Group: Natural products. Alternative Names: D-Trehalose dihydrate; α,α-Trehalose dihydrate. CAS No. 6138-23-4. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-N1132A.
D-(+)-Trehalose dihydrate (Standard)
D-(+)-Trehalose dihydrate (Standard) is the analytical standard of D-(+)-Trehalose dihydrate. This product is intended for research and analytical applications. D-(+)-Trehalose dihydrate, isolated from Saccharomyces cerevisiae, can be used as a food ingredient and pharmaceutical excipient. Uses: Scientific research. Group: Natural products. CAS No. 6138-23-4. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N1132AR.
dTRIM24
dTRIM24 is a selective bifunctional degrader of TRIM24 based on PROTAC, consists of ligands for von Hippel-Lindau and TRIM24. Uses: Scientific research. Group: Signaling pathways. CAS No. 2170695-14-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111519.
[D-Trp34]-Neuropeptide Y
[D-Trp34]-Neuropeptide Y is a potent and selective neuropeptide Y (NPY) Y 5 receptor agonist. [D-Trp34]-Neuropeptide Y is a significantly less potent agonist at the NPY Y 1 , Y 2 , Y 4 , and y 6 receptors. [D-Trp34]-Neuropeptide Y markedly increases food intake in rats [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 153549-84-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P1322.
[D-Trp8]-γ-MSH is a potent and selective agonist of melanocortin 3 (MC3) receptor , with IC 50 s of 6.7 nM, 600 nM and 340 nM for hMC3 , hMC4 and hMC5 , respectively in CHO cells. [D-Trp8]-γ-MSH could provide protection against multiple inflammatory disorders such as rheumatoid arthritis and colitis [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 321351-81-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1217.
DTSSP Crosslinker
DTSSP Crosslinker is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 81069-02-5. Pack Sizes: 5 mg. Product ID: HY-126349.
DTTCI
DTTCI (3,3-Diethylthiatricarbocyanine iodide) is an infrared photographic sensitizing dye. DTTCI is a highly sensitive chiroptical reporter of DNA helicity and sequence [1] [2]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: 3,3-Diethylthiatricarbocyanine iodide. CAS No. 3071-70-3. Pack Sizes: 250 mg; 500 mg. Product ID: HY-D1180.
D-Tyrosine
D-Tyrosine is the D-isomer of tyrosine. D-Tyrosine negatively regulates melanin synthesis by inhibiting tyrosinase activity. D-Tyrosine inhibits biofilm formation and trigger the self-dispersal of biofilms without suppressing bacterial growth [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 556-02-5. Pack Sizes: 500 mg; 1 g; 5 g. Product ID: HY-Y0444.
DU-14
DU-14 is a potent steroid sulfatase inhibitor with an IC 50 of 55.8 nM. DU-14 inhibits the MCF-7 cell proliferation ( IC 50 = 38.7 nM). DU-14 has neuroprotective effects against neurotoxic Aβ, suggesting that up-regulation of endogenous DHEAS by DU-14 could be beneficial to the alleviation of Aβ-induced impairments in spatial memory and synaptic plasticity [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 186303-55-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-116377.