MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Elaidic acid | Elaidic acid is the major trans fat found in hydrogenated vegetable oils and can be used as a pharmaceutical solvent. Uses: Scientific research. Group: Natural products. CAS No. 112-79-8. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-113016. |  |
| Elamipretide | Elamipretide (MTP-131) is a mitochondria-targeting peptide, which ameliorates myocardial infarction, improves the renal function and protects neurons form inflammatory and oxidative stress injury [1] [2]. Uses: Scientific research. Group: Peptides. Alternative Names: MTP-131; RX-31; SS-31. CAS No. 736992-21-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P0125. | |
| Elastase, Human leukocytes | Elastase, Human leukocytes is a serine protease present in the nitrogen-loving granules of neutrophils. Elastase, Human leukocytes potential substrates include almost all components of the extracellular matrix, as well as a variety of proteins such as coagulation factors, complement, immunoglobulins and cytokines. It has a strong proteolytic function and participates in the pathogenesis of inflammatory tissue damage [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 9004-6-2. Pack Sizes: 1 U. Product ID: HY-P2751. | |
| Elastase, Porcine pancreas | Elastase, Porcine pancreas (EC 3.4.21.36) is a single polypeptide chain of 240 amino acid residues, derived from pig pancreas. Elastase, Porcine pancreas is a serine protease that can hydrolyze proteins and polypeptide. Elastase from porcine pancreas can induce emphysema in hamsters [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: EC 3.4.21.36; Pancreatopeptidase E. CAS No. 39445-21-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P2974. | |
| Elastin from bovine | Elastin from bovine is a biochemical reagent. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 9007-58-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-P2841A. | |
| Elastin Methacrylated | Elastin Methacrylated (ElaMA) elastin recruits and modulates innate immune cells and accelerates angiogenesis at the wound site, thereby improving wound regeneration. Elastin Methacrylated attracts large numbers of neutrophils and primarily M2 macrophages to the wound and induces their penetration into the hydrogel. Elastin Methacrylated has excellent immunomodulatory effects, leading to superior angiogenesis, collagen deposition and dermal regeneration[1]. Elastin Methacrylated needs to self-assemble into fibrous hydrogel under the action of photoinitiator LAP (HY-44076), and target bioactive adhesion sites, play an inherent supporting role for tissue cells and biodegradable activity. Application: cell culture, biological 3D printing, tissue engineering, etc. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: ElaMA. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-158226. | |
| Elbasvir | Elbasvir (MK-8742) is a hepatitis C virus nonstructural protein 5A ( HCV NS5A ) inhibitor with EC 50 s of 4, 3 and 3 nM against genotype 1a, 1b, and 2a, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-8742. CAS No. 1370468-36-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15789. | |
| Elcubragistat | Elcubragistat (ABX-1431) is a highly potent, selective, and orally available, CNS-penetrant monoacylglycerol lipase (MAGL) inhibitor with an IC50 of 14 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ABX-1431. CAS No. 1446817-84-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-117632. | |
| Eldecalcitol | Eldecalcitol (ED-71) is an orally active vitamin D3 analogue, inhibits bone resorption and increases bone mineral density. Eldecalcitol (ED-71) displays anti-tumor effect and inhibits cell proliferation, migration and induces apoptosis by suppressing GPx-1 [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ED-71; 2-(3-hydroxypropoxy)-1,25-dihydroxyvitamin D3. CAS No. 104121-92-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-A0020. | |
| Eldelumab | Eldelumab (BMS-936557) is a human anti-CXCL10 (IP-10) monoclonal antibody (IgG1 type). Eldelumab selectively binds to CXCL10 and blocks CXCL10-induced calcium flux and cell migration. Eldelumab can be used in studies of autoimmune and auto-inflammatory diseases such as rheumatoid arthritis, ulcerative colitis and crohn's disease[1][2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: BMS-936557; MDX-1100. CAS No. 946414-98-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P99190. | |
| Eleclazine hydrochloride | Eleclazine (GS 6615) hydrochloride is a selective cardiac late sodium current inhibitor and a weak inhibitor of potassium current with IC 50 value of <1 μM and approximately 14.2 μM, respectively. Eleclazine hydrochloride shows concurrent protection against autonomically induced atrial premature beats, repolarization alternans and heterogeneity, and atrial fibrillation in porcine model. Eleclazine hydrochloride can be used to research cardiac arrhythmias [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GS 6615 hydrochloride. CAS No. 1448754-43-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16738A. | |
| Eledoisin | Eledoisin (Eledone peptide) is a specific agonist of NK2 and NK3 receptors. Uses: Scientific research. Group: Peptides. Alternative Names: Eledone peptide. CAS No. 69-25-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-P0006. | |
| Elemicin | Elemicin is an orally active alkenylbenzene widely distributed in many herbs and spices. Elemicin inhibits Stearoyl-CoA Desaturase 1 (SCD1) by metabolic activation. Elemicin has anti-influenza activities, antimicrobial , antioxidant, and antiviral activities. Elemicin and its reactive metabolite of 1-Hydroxyelemicin can induce hepatotoxicity [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. CAS No. 487-11-6. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-N6807. | |
| Elenbecestat | Elenbecestat (E2609) is a potent, orally bioavailable and CNS-penetrant BACE-1 inhibitor. Elenbecestat has the potential for Alzheimer's disease (AD) research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: E2609. CAS No. 1388651-30-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109055. | |
| Elenestinib | Elenestinib (BLU-263) is an orally active inhibitor of Tyrosine kinase with an IC 50 value of 6 nM for KIT D816V. Elenestinib minimally penetrates the blood-brain barrier. Elenestinib can be used in the study of systemic mastocytosis [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BLU-263. CAS No. 2505078-08-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-152839. | |
| Elesclomol | Elesclomol (STA-4783) is a potent copper ionophore and promotes copper-dependent cell death (cuproptosis). Elesclomol specifically binds ferredoxin 1 (FDX1) ?2/?3 helices and ?5 strand. Elesclomol inhibits FDX1-mediated Fe-S cluster biosynthesis. Elesclomol is an oxidative stress inducer that induces cancer cell apoptosis. Elesclomol is a reactive oxygen species (ROS) inducer. Elesclomol can be used for Menkes and associated disorders of hereditary copper deficiency research[1][2][3][4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: STA-4783. CAS No. 488832-69-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-12040. | |
| Eletriptan hydrobromide | Eletriptan hydrobromide (Eletriptan HBr) is a 5-HT 1B and 5-HT 1D receptor agonist with antimigraine activity, with K i of 0.92 nM and 3.14 nM, respectively [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Eletriptan HBr; UK-116044 hydrobromide. CAS No. 177834-92-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-A0010. | |
| Eleutheroside E | Eleutheroside E is an important component of ginseng that can be taken orally. Eleutheroside E has anti-inflammatory and antioxidant properties, and it helps reduce apoptosis in heart cells caused by hypoxia-reoxygenation (H/R) damage. Eleutheroside E can improve type 2 diabetes, enhance cognitive function, and has neuroprotective effects [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. CAS No. 39432-56-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0272. | |
| Elevenostat | Elevenostat (JB3-22) is a selective HDAC11 inhibitor with an IC50 of 0.235 μM. Elevenostat can induce apoptosis of multiple myeloma cells and has anti-tumor effect. In addition, Elevenostat inhibits the maturation of mouse oocytes[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: JB3-22. CAS No. 1454902-97-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145757. | |
| Elexacaftor | Elexacaftor (VX-445, Compound 1) is a modulator of cystic fibrosis transmembrane conductance regulator (CFTR). Elexacaftor (VX-445, Compound 1) facilitates the processing and trafficking of CFTR to increase the amount of CFTR at the cell surface [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: VX-445. CAS No. 2216712-66-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111772. | |
| Elezanumab | Elezanumab (ABT-555; AE12-1Y-QL) is a human monoclonal antibody that selectively targets repulsive guidance molecule A (RGMa). Elezanumab potently inhibited RGMa mediated BMP signalling via the SMAD1/5/8 pathway, with an IC 50 around 97 pM. Elezanumab promotes neuroregeneration and neuroprotection in neuronal injury and demyelination models binds N-terminal RGMa, blocks BMP signaling and lacks RGMc cross-reactivity. elezanumab has neuroregenerative and neuroprotective activities without impact on iron metabolism [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: ABT-555; AE12-1Y-QL; Anti-RGMA Reference Antibody (elezanumab). CAS No. 1791416-49-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99359. | |
| ELF97 phosphate | ELF97 phosphate (ELFP) is a phosphatase substrate, which can produced a fluorescent, water-insoluble product ELF97 alcohol after hydrolysis by phosphatases. ELF97 phosphate can be utilized to study and quantify the activity of extracellular phosphatases of algae in natural water [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ELFP. CAS No. 147394-94-3. Pack Sizes: 1 mg. Product ID: HY-160973. | |
| Elgemtumab | Elgemtumab(LJM716) is a fully human IgG monoclonal antibody. Elgemtumab can specifically bind to HER3, block ligand-dependent and independent HER3 signal transduction and cell proliferation, and has good anti-tumor potential[1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: LJM716. CAS No. 1512559-37-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99936. | |
| Eliapixant | Eliapixant (BAY 1817080) is a potent and selective antagonist of P2X3 receptor , with an IC 50 of 8 nM. Eliapixant can be used for the research of refractory chronic cough [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY 1817080. CAS No. 1948229-21-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109170. | |
| Eliglustat | Eliglustat is an specific, potent and orally active glucocerebroside synthase inhibitor with an IC 50 of 24 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Genz 99067. CAS No. 491833-29-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14885. | |
| Eliglustat hemitartrate | Eliglustat hemitartrate is an specific, potent and orally active glucocerebroside synthase inhibitor with an IC50 of 24 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Genz-112638; Eliglustat tartrate. CAS No. 928659-70-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-14885A. | |
| Elimusertib | Elimusertib (BAY-1895344) is a potent, orally active and selective ATR inhibitor with an IC 50 of 7 nM. Elimusertib has anti-tumor activity [1] [2]. Elimusertib can be used for the research of solid tumors and lymphomas [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY 1895344. CAS No. 1876467-74-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101566. | |
| Elimusertib hydrochloride | Elimusertib (BAY 1895344) hydrochloride is a potent, orally active and selective ATR inhibitor with an IC50 of 7 nM. Elimusertib hydrochloride has anti-tumor activity[1][2]. Elimusertib hydrochloride can be used for the research of solid tumors and lymphomas[3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY 1895344 hydrochloride. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101566A. | |
| Elinogrel | Elinogrel (PRT060128) is a potent, direct acting, competitive, and reversible platelet P2Y 12 antagonist ( IC 50 =20 nM). It is orally and intravenously available and has potent antiplatelet effects [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PRT060128. CAS No. 936500-94-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-11021. | |
| Elinzanetant | Elizanetant (NT-814) is an orally active, selective NK-1,3 receptor antagonist. Elizanetant can reduce the levels of estradiol and progesterone, and is used in the study of vascular motor symptoms and sleep disorders related to menopause in women [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NT-814; BAY3427080. CAS No. 929046-33-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109171. | |
| Elipovimab | Elipovimab is a potent broadly neutralizing HIV-1 antibody for the targeted elimination of HIV-infected cells [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 2101210-43-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99937. | |
| Eliprodil | Eliprodil(SL-820715) is a non-competitive NR2B-NMDA receptor antagonist(IC50=1 uM), less potent for NR2A- and NR2C-containing receptors(IC50> 100 uM). Uses: Scientific research. Group: Signaling pathways. Alternative Names: SL-820715. CAS No. 119431-25-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12881. | |
| Elironrasib | Elironrasib is an orally active and covalent inhibitor of KRASG12C(ON). Elironrasib forms a tri-complex within tumor cells between KRASG12C(ON) and cyclophilin A (CypA). Thus, Elironrasib prevents KRASG12C(ON) from signaling via steric blockade of RAS effector binding. Elironrasib inhibits ERK signaling and induced apoptosis in KRASG12C-mutant H358 cells. Elironrasib also inhibits the proliferation of KRASG12C mutant cells with a median IC50 of 0.11 nM[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RMC-6291. CAS No. 2641998-63-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153346. | |
| Ellagic acid | Ellagic acid is a natural antioxidant, and acts as a potent and ATP-competitive inhibitor of CK2 and SHP2 , with an IC 50 of 40 nM and a K i of 20 nM. Uses: Scientific research. Group: Natural products. CAS No. 476-66-4. Pack Sizes: 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-B0183. | |
| Ellipticine | Ellipticine (NSC 71795) is a potent antineoplastic agent; inhibits DNA topoisomerase II activities. Uses: Scientific research. Group: Natural products. Alternative Names: NSC 71795. CAS No. 519-23-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-15753. | |
| Ellipticine hydrochloride | Ellipticine (NSC 71795) hydrochloride is a potent antineoplastic agent; inhibits DNA topoisomerase II activities. Uses: Scientific research. Group: Natural products. Alternative Names: NSC 71795 hydrochloride. CAS No. 5081-48-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15753A. | |
| Elobixibat | Elobixibat (A 3309; AZD 7806) is an orally effective Apical Sodium-Dependent Bile (IBAT) inhibitor, with an IC 50 value of 0.53 nM (human IBAT ), 0.13 nM (mouse IBAT), 5.8 nM (canine IBAT). Elobixibat lowers LDL cholesterol, increases serum GLP-1, promotes colon motility, and has the potential to treat metabolic syndrome. Elobixibat can be used to study constipation, dyslipidemia, non-alcoholic hepatitis, and liver tumors [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: A 3309; AZD 7806. CAS No. 439087-18-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15790. | |
| Elobixibat hydrate | Elobixibat hydrate is a potent ileal bile acid transporter (IBAT) inhibitor, with IC 50 values of 0.53 ± 0.17 nM, 0.13 ± 0.03 nM, and 5.8 ± 1.6 nM for human IBAT, mouse IBAT, and canine IBAT. Elobixibat hydrate can be used for chronic idiopathic constipation (CIC) research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: A 3309 hydrate; AZD 7806 hydrate. CAS No. 1633824-78-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15790A. | |
| Eloralintide | Eloralintide (LY 3841136) is an AMYR agonist, which is promising for research of type 2 diabetes and obesity[1]. Uses: Scientific research. Group: Peptides. Alternative Names: LY-3841136. CAS No. 2883634-40-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P10798. | |
| Elotuzumab | Elotuzumab is a monoclonal antibody directed against the SLAMF7 receptor. Elotuzumab has no significant antimyeloma activity when given as a single agent with relapsed or refractory multiple myeloma (RRMM). Elotuzumab results in improved response and outcome when combined with other antimyeloma agents [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: HuLuc 63; PDL 063; BMS 901608. CAS No. 915296-00-3. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P9965. | |
| ELOVL1-IN-1 | ELOVL1-IN-1 is an ELOVL1 inhibitor extracted from patent WO2018107056A1, compound 87. ELOVL1-IN-1 can reduce very long chain fatty acid levels. ELOVL1-IN-1 can be used for the research of adrenoleukodystrophy (ALD)[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2227482-41-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145122. | |
| ELOVL1-IN-3 | ELOVL1-IN-3 (Compound 22) is a potent and orally active inhibitor of elongation of very long chain fatty acid 1 (ELOVL1) enzyme. ELOVL1-IN-3 serves as a useful tool for researching adrenoleukodystrophy (ALD)[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2761063-99-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145272. | |
| ELOVL6-IN-2 | ELOVL6-IN-2 is a potent, orally active and selective ELOVL6 inhibitor. ELOVL6-IN-2 inhibits mouse ELOVL6 activities, with an IC50 value of 34 nM[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1067647-43-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12146. | |
| ELOVL6-IN-4 | ELOVL6-IN-4 is a potent, selective, and orally active long chain fatty acid elongase 6 (ELOVL6) inhibitor with IC50s of 79 nM and 94 nM for human and mouse ELOVL6, respectively. ELOVL6-IN-4 shows excellent selectivity over the other human ELOVL subtypes (ELOVL1, -2, -3, and -5) and mouse ELOVL3[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1170321-92-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-152947. | |
| Elranatamab | Elranatamab (PF-06863135) is an anti- CD3E/TNFRSF17 human IgG2κ monoclonal antibody [1]. Recommend Isotype Controls: Human IgG2 kappa, Isotype Control (HY-P99002). Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: PF-06863135. CAS No. 2408850-14-4. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P99909. | |
| Elsilimomab | Elsilimomab (B-E8) is a IgG1 monoclonal antibody against interleukin-6 (IL-6) , with a K D of 22 pM and an IC 50 of 1.4 nM. Elsilimomab can be used for the research of multiple myeloma, renal cell carcinoma, and rheumatoid arthritis (RA) [1] [2] [3]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: B-E8; Anti-IL-6 MAB B-E8; Anti-Human IL6 Recombinant Antibody. CAS No. 468715-71-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99287. | |
| Elsulfavirine | Elsulfavirine is a reverse transcriptase inhibitors for HIV-1 infection and is a new anti-HIV agent [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: R-1206. CAS No. 868046-19-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109056. | |
| Eltanexor | Eltanexor (KPT-8602) is a second-generation, highly specific and orally active exportin-1 (XPO1) inhibitor with potent anti-leukemic activity. Eltanexor (KPT-8602) inhibits XPO1-dependent nuclear export ( EC 50 =60.9 nM) by directly targeting XPO1. Eltanexor (KPT-8602) induces Caspase-dependent apoptosis in a panel of leukemic cell lines [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KPT-8602. CAS No. 1642300-52-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-100423. | |
| Eltoprazine hydrochloride | Eltoprazine (DU 28853) hydrochloride is a 5-HT1A/5-HT1B receptors agonist and a 5-HT2C receptor antagonist. Eltoprazine hydrochloride shows antiaggressive and anxiogenic effects [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DU 28853 hydrochloride. CAS No. 98206-09-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16687A. | |
| Eltrombopag | Eltrombopag (SB-497115) is an orally active thrombopoietin receptor nonpeptide agonist. Eltrombopag owns thrombopoietic activity, and has been used to research low blood platelet counts with chronic immune thrombocytopenia. Eltrombopag can be used for the research of cardiovascular. Eltrombopag also has highly inhibitory effects against multidrug resistant Staphylococcus aureus. Eltrombopag can induce apoptosis in hepatocellular carcinomab (HCC) as well [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SB-497115. CAS No. 496775-61-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15306. | |
| Eltrombopag-13C4 | Eltrombopag- 13 C 4 (SB-497115- 13 C 4 ) is 13 sup>C-labeled Z-Eltrombopag. Z-Eltrombopag is an orally active thrombopoietin-receptor non-peptide agonist with platelet-stimulating activity for the study of chronic immune thrombocytopenia. Eltrombopag also has strong inhibitory effects on multidrug-resistant Staphylococcus aureus ( Staphylococcus aureus ) and can induce apoptosis ( apoptosis ) in liver cancer cells [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: SB-497115- 13 C4. CAS No. 1217230-31-3. Pack Sizes: 1 mg. Product ID: HY-15306S. | |
| Eltrombopag Olamine | Eltrombopag Olamine (Eltrombopag diethanolamine salt) is an orally active thrombopoietin receptor nonpeptide agonist. Eltrombopag Olamine owns thrombopoietic activity, and has been used to research low blood platelet counts with chronic immune thrombocytopenia. Eltrombopag Olamine can be used for the research of cardiovascular. Eltrombopag Olamine also has highly inhibitory effects against multidrug resistant Staphylococcus aureus. Eltrombopag Olamine can induce apoptosis in hepatocellular carcinomab (HCC) as well [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Eltrombopag diethanolamine salt; SB-497115GR. CAS No. 496775-62-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15306A. | |
| Elubrixin tosylate | Elubrixin tosylate (SB-656933 tosylate) is a potent, selective, competitive, reversible and orally active CXCR2 antagonist and an IL-8 receptor antagonist. Elubrixin tosylate inhibits neutrophil CD11b upregulation ( IC 50 of 260.7 nM) and shape change ( IC 50 of 310.5 nM). Elubrixin tosylate has the potential for inflammatory diseases research, such as inflammatory bowel disease and airway inflammation [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SB-656933 tosylate. CAS No. 960495-43-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18263C. | |
| Elvitegravir | Elvitegravir (GS-9137; JTK-303; D06677) is an HIV integrase inhibitor for HIV-1 IIIB , HIV-2 EHO and HIV-2 ROD with IC 50 of 0.7 nM, 2.8 nM and 1.4 nM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GS-9137; JTK-303; D06677. CAS No. 697761-98-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14740. | |
| Elzovantinib | Elzovantinib (TPX-0022) is an oral-active inhibitor of SRC , MET and c-FMS , with IC 50 values of 0.12 nM, 0.14 nM and 0.76 nM for SRC, MET and c-FMS respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TPX-0022; CSF1R-IN-2. CAS No. 2271119-26-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111787. | |
| Emactuzumab | Emactuzumab(RG 7155) is a specific monoclonal antibody that inhibits colonystimulating factor 1 receptor (CSF1R) activation. Emactuzumab has high affinity for CSF-1R with K i value of 0.2 nM to blocks CSF-1R dimerization. Emactuzumab can be used for the research of several diseases, such as diffuse-type tenosynovial giant cell tumour (dt-GCT) [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: RG 7155; RO 5509554. CAS No. 1448221-67-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99245. | |
| Emamectin Benzoate | Emamectin Benzoate (MK-244) is an orally active nervoussystem toxicant by binding g-aminobutyric ( GABA ) receptor in insects. Emamectin Benzoate is one of semi-synthetic derivative of Avermectin (HY-15311) with a broadspectrum of insecticidal and acaricidal activity. Emamectin Benzoate induces ROS-mediated DNA damage and cell apoptosis. Emamectin Benzoate, a mixture of the natural Emamectin B1a benzoate and Emamectin B1b benzoate, has the main component of Emamectin B1a benzoate [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-244. CAS No. 155569-91-8. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0837. | |
| Emapalumab | Emapalumab (NI-0501) is a human monoclonal IgG1 antibody that noncompetitively inhibits IFN-&gamma. Emapalumab binds with high affinity ( K d = 1.4 pM) to both free IFN-γ as well as IFN-γ bound to its receptor. Emapalumab can be used in research of hemophagocytic lymphohistiocytosis (HLH) [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: NI-0501. CAS No. 1709815-23-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99191. | |
| Emavusertib | Emavusertib is an orally active inhibitor for IRAK4 ( IC 50 =57 nM) and FLT3. Emavusertib inhibits NF-κB and MyD88 signaling pathways, reduces the generation of pro-inflammatory cytokines like IL-6 and IL-10, thereby exhibiting anti-inflammatory and anti-proliferative activities against cancer cells, leading to cell apoptosis. Emavusertib exhibits antitumor activity in mouse model. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CA-4948. CAS No. 1801344-14-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-135317. | |
| Embelin | Embelin (Embelic acid), a potent, nonpeptidic XIAP inhibitor ( IC 50 =4.1 μM), inhibits cell growth, induces apoptosis , and activates caspase-9 in prostate cancer cells with high levels of XIAP. Embelin blocks NF-kappaB signaling pathway leading to suppression of NF-kappaB-regulated antiapoptotic and metastatic gene products. Embelin also induces autophagic and apoptotic cell death in human oral squamous cell carcinoma cells [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Embelic acid; Emberine; NSC 91874. CAS No. 550-24-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-17473. | |
| EMD386088 | EMD386088 is a potent serotonin 6 receptor (5-HT6R) agonist. EMD386088 induces cell death. EMD386088 regulates the activity of ERK1/2. EMD386088 has the potential for the research of alzheimer's disease (AD) and schizophrenia [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1171123-46-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-103130. | |
| (+)-EMD 57033 | (+)-EMD 57033 is a cardiac troponin C (cTnC) activator, is a dominant Ca2+ sensitizer. (+)-EMD 57033 binds the cardiac/slow skeletal troponin C isoform and exerts myocardial contractile promotion function[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 147527-31-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-106844A. | |
| EMD638683 | EMD638683 is a highly selective SGK1 inhibitor, with an IC50 value of 3 ?M. Uses: Scientific research. Group: Signaling pathways. CAS No. 1181770-72-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15193. | |
| Emedastine | Emedastine is an orally active, selective and high affinity histamine H 1 receptor antagonist with a K i value of 1.3 nM. Emedastine is a benzimidazole derivative with potent antiallergic properties and used for allergic rhinitis, allergic skin diseases and allergic conjunctivitis [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 87233-61-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-108411. | |
| Emeramide | Emeramide is a thiol-redox antioxidant and heavy metal chelator[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NBMI; BDTH2. CAS No. 351994-94-0. Pack Sizes: 100 mg; 500 mg; 1 g. Product ID: HY-16739. | |
| EMI1 | EMI1 is an EGFR ex19del/T790M/C797S and EGFR L858R/T790M/C797S inhibitor. EMI1 can be used for the research of mutant EGFR-associated, drug-resistant non-small-cell lung cancer (NSCLC) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 35773-42-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-138072. | |
| EMI48 | EMI48, the derivative of EMI1, displays greater potency toward mutant EGFR than EMI1. EMI48 inhibits EGFR triple mutants [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 34564-13-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-131066. | |
| Emibetuzumab | Emibetuzumab (LY2875358) is a humanized bivalent MET antibody (IgG4 type). Emibetuzumab shows high neutralization and internalization activities, resulting in inhibition of both HGF -dependent and HGF -independent MET pathway activation and tumor growth. Emibetuzumab can be used in study of cancer [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: LY2875358. CAS No. 1365287-97-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99192. | |
| Emicerfont | Emicerfont is a corticotropin-releasing factor type 1 ( CRF 1 ) receptor antagonist with an IC 50 of 66 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GW876008. CAS No. 786701-13-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14367. | |
| Emicizumab | Emicizumab is a bispecific monoclonal antibody that bridges activated factor IX and factor X to replace the function of missing activated factor VIII, thereby restoring hemostasis. Emicizumab can be used for hemophilia A research [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 1610943-06-0. Pack Sizes: 1 mg. Product ID: HY-P9940. | |
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