MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Glycohyodeoxycholic acid | Glycohyodeoxycholic acid is a major metabolite of Hyodeoxycholic acid in humans. Glycohyodeoxycholic acid has preventative effects on gallstone formation [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 13042-33-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-126995. |  |
| Glycolic acid | Glycolic acid is an inhibitor of tyrosinase , suppressing melanin formation and lead to a lightening of skin colour. Uses: Scientific research. Group: Natural products. Alternative Names: Hydroxyethanoic acid. CAS No. 79-14-1. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-W015967. | |
| Glycolithocholic acid | Glycolithocholic acid (Lithocholylglycine), an endogenous metabolite, is a glycine-conjugated secondary bile acid. Glycolithocholic acid can be used to diagnose ulcerative colitis (UC), non-alcoholic steatohepatitis (NASH) and primary sclerosing cholangitis (PSC) [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: Lithocholylglycine. CAS No. 474-74-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116374. | |
| Glycolithocholic acid 3-sulfate disodium | Glycolithocholic acid 3-sulfate (disodium) inhibits replication of HIV-1 in vitro. Glycolithocholic acid 3-sulfate (disodium) can be used for the research of HIV infection and gallbladder disease [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Glycolithocholate sulfate disodium; Sulfolithocholylglycine disodium; SLCG disodium. CAS No. 64936-82-9. Pack Sizes: 1 mg. Product ID: HY-W587430. | |
| Glycolithocholic acid-d4 | Glycolithocholic acid-d 4 is the deuterium labeled Glycolithocholic acid. Glycolithocholic acid, an endogenous metabolite, is a glycine-conjugated secondary bile acid and can be used to diagnose ulcerative colitis (UC), non-alcoholic steatohepatitis (NASH) and primary sclerosing cholangitis (PSC) [1][2][3][4]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: Lithocholylglycine-d4. CAS No. 2044276-16-4. Pack Sizes: 500 μg; 1 mg. Product ID: HY-116374S. | |
| Glycolithocholic acid sodium | Glycolithocholic acid (Lithocholylglycine) sodium is the sodium salt of Glycolithocholic acid. Glycolithocholic acid is a glycine-conjugated secondary bile acid. Glycolithocholic acid can be used to diagnose ulcerative colitis (UC), non-alcoholic steatohepatitis (NASH) and primary sclerosing cholangitis (PSC) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Lithocholylglycine sodium. CAS No. 24404-83-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116374A. | |
| Glycol salicylate | Glycol salicylate is a derivative of salicylic acid and can be used to improve the aesthetic appearance of the skin, extracted from patent US 20150148320 A1. Uses: Scientific research. Group: Signaling pathways. CAS No. 87-28-5. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-B2208. | |
| Glycopyrrolate | Glycopyrrolate (Glycopyrronium bromide), a quaternary ammonium derivative, is a muscarinic receptor antagonist. Glycopyrrolate has bronchoprotective effect and produces a beneficial effect on blood pressure. Glycopyrrolate can be used for the research of bronchial diseases [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Glycopyrronium bromide; Glycopyrrolate bromide. CAS No. 596-51-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17465. | |
| Glycoursodeoxycholic Acid-d4 | Glycoursodeoxycholic acid-d4 (Ursodeoxycholylglycine-d4) is the deuterium labeled Glycoursodeoxycholic acid. Glycoursodeoxycholic acid, a acyl glycine and a bile acid-glycine conjugate, is a metabolite of ursodeoxycholic acid[1][2]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 2044276-17-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N1424S. | |
| Glycozolidal | Glycozolidal (compound 12) is a carbazole alkaloid with antibacterial activity against P. gingivalis. Glycozolidal is cytotoxic against human gingival fibroblasts (HGFs) and monocytes (U937) in vitro with IC 50 values ??of 120.86 μg/mL and 97.74 μg/mL, respectively [1]. Uses: Scientific research. Group: Natural products. CAS No. 51971-09-6. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-N13286. | |
| Glycyl-DL-phenylalanine | Glycyl-DL-phenylalanine is a phenylalanine derivative [1]. Uses: Scientific research. Group: Peptides. CAS No. 721-66-4. Pack Sizes: 1 g; 5 g; 10 g. Product ID: HY-W014000. | |
| Glycylglycine | Glycylglycine is the simplest of all peptides and could function as a gamma-glutamyl acceptor. Uses: Scientific research. Group: Peptides. CAS No. 556-50-3. Pack Sizes: 10 mM * 1 mL; 500 mg; 5 g. Product ID: HY-D0889. | |
| Glycylglycine (Standard) | Glycylglycine (Standard) is the analytical standard of Glycylglycine. This product is intended for research and analytical applications. Glycylglycine is the simplest of all peptides and could function as a gamma-glutamyl acceptor. Uses: Scientific research. Group: Peptides. CAS No. 556-50-3. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-D0889R. | |
| Glycyl-L-phenylalanine | Glycyl-L-phenylalanine is a phenylalanine derivative [1]. Uses: Scientific research. Group: Peptides. CAS No. 3321-3-7. Pack Sizes: 1 g; 5 g. Product ID: HY-W013998. | |
| Glycyl-L-tyrosine | Glycyl-L-tyrosine is a dipeptide containing glycine and L-tyrosine [1]. Uses: Scientific research. Group: Natural products. CAS No. 658-79-7. Pack Sizes: 5 g. Product ID: HY-W009592. | |
| Glycyl-L-valine | Glycyl-L-valine is a dipeptide that contains glycine and valine. Uses: Scientific research. Group: Natural products. CAS No. 1963-21-9. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-W016785. | |
| Glycyrrhizic acid | Glycyrrhizic acid is a triterpenoid saponinl, acting as a direct HMGB1 antagonist, with anti-tumor, anti-diabetic activities. Uses: Scientific research. Group: Natural products. Alternative Names: Glycyrrhizin. CAS No. 1405-86-3. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 500 mg. Product ID: HY-N0184. | |
| Gly-Gly-Phe-Gly | Gly-Gly-Phe-Gly is a peptide spacer and can be applied to Doxorubicin (HY-15142A) (DXR) conjugates [1]. Uses: Scientific research. Group: Peptides. CAS No. 200427-88-9. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P3669. | |
| GlyH-101 | GlyH-101 is a potent CFTR inhibitor. GlyH-101 also is a potent and reversible inhibitor of the VSORC conductance. GlyH-101 shows antiproliferative activity. GlyH-101 inhibits CFTR-like current and VSORC current [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 328541-79-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-18336. | |
| Glymidine sodium | Glymidine sodium is an oral active antidiabetic. Glymidine sodium is the inhibitor of hepatic lipolysis. Glymidine sodium inhibits the glucose formation and supresses the elevated pyruvate oxidation which results from the inhibition of endogenous lipid mobilization [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Gondafon; Glycodiazine. CAS No. 3459-20-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-A0231. | |
| Glyoxalase I | Glyoxalase I (Glo-I) is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Glo-I. CAS No. 9033-12-9. Pack Sizes: 100 U. Product ID: HY-P2774. | |
| Glyoxalase I inhibitor 5 | Glyoxalase I inhibitor 5 (Compound 9h) is a glyoxalase I (Glo-I) inhibitor with an IC 50 of 1.28 μM. Glyoxalase I inhibitor 5 can be used as anticancer agent [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2455508-17-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-147647. | |
| Glyoxalic acid (50% in water) | Glyoxalic acid (NSC 27785) (50% in water) is an organic compound that is both an aldehyde and a carboxylic acid. Glyoxalic acid (50% in water) induces fluorescence. Glyoxalic acid (50% in water) is used to study neurons [1]. Uses: Scientific research. Group: Natural products. Alternative Names: NSC 27785; Formylformic acid; Oxalaldehydic acid. CAS No. 298-12-4. Pack Sizes: 500 mg (6.75 M * 1 mL in Water); 1 g (6.75 M * 2 mL in Water). Product ID: HY-79494. | |
| Glyphosate | Glyphosate, a non-selective systemic biocide with broad-spectrum activity, is an herbicidal derivative of the amino acid glycine. Glyphosate inhibits the enzymatic activity of the 5-endopyruvylshikimate 3-phosphate synthase (EPSPS) in the shikimic acid pathway, preventing the synthesis of the aromatic amino acids tyrosine, phenylalanine, and tryptophan. Glyphosate induces oxidative stress, neuroinflammation, and mitochondrial dysfunction, processes that lead to neuronal death by autophagia , necrosis , or apoptosis , as well as the appearance of behavioral and motor disorders [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 1071-83-6. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-B0863. | |
| Gly-Pro-AMC hydrobromide | Gly-Pro-AMC hydrobromide is a fluorescent dye, it can be used as a specific fluorescent substrate for detecting Dipeptidyl peptidase IV (DPP-IV) activity [1] [2]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 115035-46-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-137834. | |
| GMBS | GMBS is a heterobifunctional cross-linker. GMBS can be used in chemical cross-linking of proteins coupled with mass spectrometry (CXMS) to study protein folding and to map the interfaces between interacting proteins [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 80307-12-6. Pack Sizes: 10 mg; 50 mg; 100 mg. Product ID: HY-W041994. | |
| GMQ | GMQ is a ASIC (acid-sensing ion) channel activator with an EC 50 value of 1.83 mM for ASIC3 at pH 7.4. GMQ opens only ASIC3 but no other ASICs at pH 7.4. GMQ can be used for neurological disease research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 5361-15-9. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-107757. | |
| GNE-140 racemate | GNE-140 racemate is a racemate mixture of (R)-GNE-140 and (S)-GNE-140. GNE-140 racemate is a potent lactate dehydrogenase A (LDHA) inhibitor [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1802977-61-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-100742. | |
| GNE-617 | GNE-617 is a specific NAMPT inhibitor that inhibits the biochemical activity of NAMPT with an IC 50 of 5 nM and exhibits efficacy in xenograft models of cancer. Uses: Scientific research. Group: Signaling pathways. CAS No. 1362154-70-8. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15766. | |
| GNE-617 hydrochloride | GNE-617 hydrochloride is a specific NAMPT inhibitor that inhibits the biochemical activity of NAMPT with an IC 50 of 5 nM and exhibits efficacy in xenograft models of cancer. Uses: Scientific research. Group: Signaling pathways. CAS No. 2070014-99-0. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15766A. | |
| GNF2133 | GNF2133 is a potent, selective and orally active DYRK1A inhibitor with IC 50 s of 0.0062, >50 μM for DYRK1A and GSK3β, respectively. GNF2133 shows good proliferation potency and efficacy on rat and human primary β-cell. GNF2133 significantly improves glucose disposal capacity and increases insulin secretion. GNF2133 has the potential for the research of type 1 diabetes [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2561414-56-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-142295. | |
| GNF-5837 | GNF-5837 is a potent, selective, and orally bioavailable pan- tropomyosin receptor kinase (TRK) inhibitor which display antiproliferative effects in cellular Ba/F3 assays ( IC 50 values of 7 nM, 9 nM and 11 nM for cells containing the fusion proteins Tel-TrkC , Tel-TrkB and Tel-TrkA , respectively) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1033769-28-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13491. | |
| GO-203 TFA | GO-203 TFA is a potent MUC1-C oncoprotein inhibitor. GO-203 TFA is an all D-amino acid peptide that consists of a poly-R transduction domain linked to a CQCRRKN motif that binds to the MUC1-C cytoplasmic tail and blocks MUC1-C homodimerization. GO-203 TFA downregulates TIGAR (TP53-induced glycolysis and apoptosis regulator) protein synthesis by inhibiting the PI3K-AKT-S6K1 pathway. GO-203 TFA induces the production of ROS and loss of mitochondrial transmembrane potential. GO-203 TFA inhibits the growth of colon cancer cells in vitro and as xenografts in nude mice [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 1222186-26-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1925A. | |
| Go6976 | Go6976 is a Protein Kinase C ( PKC ) inhibitor, with an IC 50 of 20 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 136194-77-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-10183. | |
| Goflikicept | Goflikicept (RPH 104) is a fusion protein that selectively binds and inactivates both circulating IL-1β and IL-1&alpha. Goflikicept has the potential for the research of ST-segment elevation myocardial infarction (STEMI) [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: RPH 104. CAS No. 2416984-26-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99645. | |
| Golcadomide | Golcadomide (CC-99282) is a potent and orally active CRBN E3 ligase modulator (CELMoD). Golcadomide interacts with the CRL4 CRBN E3 ubiquitin ligase substrate receptor CRBN, inducing the recruitment and ubiquitin-mediated proteasomal degradation of the transcription factors Ikaros and Aiolos. Golcadomide shows potential for research in cancer-related fields, including chronic lymphocytic leukemia (CLL) and non-Hodgkin lymphoma (NHL) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CC-99282. CAS No. 2379572-34-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-146237. | |
| Gold(?) chloride hydrate (50% Au basis) | Gold(?) chloride hydrate (50% Au basis) (Tetrachloroauric(?) acid hydrate (50% Au basis)) is an organic intermediate that can be used to prepare gold nanoparticles. Gold(?) chloride hydrate (50% Au basis) is a kind of biological materials or organic compounds that are widely used in life science research [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Tetrachloroauric(?) acid hydrate (50% Au basis). CAS No. 27988-77-8. Pack Sizes: 100 mg; 500 mg. Product ID: HY-W073196A. | |
| Gold(III) chloride trihydrate | Gold (III) chloride trihydrate is a reducing agent. Gold (III) chromium trihydrate can be used for chemical synthesis of gold nanoparticles (NP) and spirochromene derivatives [1] [2]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 16961-25-4. Pack Sizes: 100 mg; 500 mg; 1 g. Product ID: HY-W094581. | |
| Golgicide A | Golgicide A (GCA) is a potent, highly specific, and reversible inhibitor of the cis-Golgi ADP-ribosylation factor guanine nucleotide exchange factors (ArfGEF) GBF1 [1]. Golgicide A drastically reduced replication of coxsackievirus B3 (CVB3) and other human enterovirus species [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GCA. CAS No. 1139889-93-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100540. | |
| Golgicide A-1 | Golgicide A-1 (GCA-1) is a less active cis-diastereomer of Golgicide A (GCA). Golgicide A-1 weakly inhibits mosquito reproduction [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GCA-1. CAS No. 1394285-49-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100540C. | |
| Golidocitinib | Golidocitinib (AZD4205) is a selective JAK1 inhibitor, with an IC 50 of 73 nM, weakly inhibits JAK2 ( IC 50 >14.7 μM), and shows little inhibition on JAK3 ( IC 50 >30 μM) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AZD4205. CAS No. 2091134-68-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-107361. | |
| Golimumab | Golimumab (CNTO-148) is a potent human IgG1 TNFα antagonist monoclonal antibody. Golimumab has anti-inflammation activitity and inhibits IL-6 and IL-1β production. Golimumab acts via targeting and neutralizing TNF to prevent inflammation and destruction of cartilage and bone. Golimumab has the anticancer activity and induces cell apoptosis. Golimumab can be used for rheumatoid arthritis, Crohn's disease and cancer research [1] [2] [3]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: CNTO-148. CAS No. 476181-74-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P99111. | |
| Golvatinib | Golvatinib (E-7050) is a potent dual inhibitor of both c-Met and VEGFR2 kinases with IC 50 s of 14 and 16 nM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: E-7050. CAS No. 928037-13-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13068. | |
| Gondoic acid | Gondoic acid (cis-11-Eicosenoic acid), a monounsaturated long-chain fatty acid, is contained in a variety of plant oils and nuts [1]. Uses: Scientific research. Group: Natural products. Alternative Names: cis-11-Eicosenoic acid. CAS No. 5561-99-9. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-W013242. | |
| Goralatide TFA | Goralatide TFA is an inhibitor of cell cycle progression. Goralatide TFA enhances selectivity of hyperthermic purging of human progenitor cells. Goralatide TFA has the potential for the research of leukemia [1]. Uses: Scientific research. Group: Peptides. CAS No. 1796568-94-9. Pack Sizes: 1 mg. Product ID: HY-129283A. | |
| Goserelin acetate | Goserelin acetate (ICI-118630 acetate), a decapeptide analogue of gonadotropin-releasing hormone (GnRH/LHRH), functions as a GnRH agonist. Goserelin acetate can be used for the research of breast cancer, epithelial ovarian cancer and prostate cancer [1] [2]. Uses: Scientific research. Group: Peptides. Alternative Names: ICI-118630 acetate. CAS No. 145781-92-6. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13673A. | |
| Gossypetin | Gossypetin is a hexahydroxylated flavonoid and is a potent mitogen-activated protein kinase kinase (MKK)3 and MKK6 inhibitor with strongly attenuates the MKK3/6-p38 signaling pathway, has various pharmacological activities, including antioxidant, antibacterial and anticancer activities [1]. Uses: Scientific research. Group: Natural products. CAS No. 489-35-0. Pack Sizes: 1 mg; 5 mg. Product ID: HY-119917. | |
| Gossypin | Gossypin is a flavone isolated from Hibiscus vitifolius and has antioxidant, antiinflammatory, anticancer, anticataract, antidiabetic, and hepatoprotective activities. Gossypin inhibits NF-κB and NF-κB-regulated gene expression. Gossypin inhibits RANKL-induced osteoclastogenesis both in mouse primary bone marrow cells and RAW 264.7 cells in vitro [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 652-78-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-125911. | |
| Gossypol | Gossypol binds to Bcl-xL protein and Bcl-2 protein with K i s of 0.5-0.6 μM and 0.2-0.3 mM, respectively. Uses: Scientific research. Group: Natural products. Alternative Names: BL 193. CAS No. 303-45-7. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-13407. | |
| Gossypol (acetic acid) | Gossypol acetic acid ((±)-Gossypol-acetic acid) binds to Bcl-xL protein and Bcl-2 protein with K i s of 0.5-0.6 μM and 0.2-0.3 mM, respectively. Uses: Scientific research. Group: Natural products. Alternative Names: (±)-Gossypol-acetic acid; BL-193 (acetic acid). CAS No. 12542-36-8. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-17510. | |
| Gossypolone | Gossypolone is an RNA-binding protein Musashi-1 inhibitor with a K i of 12 nM. Gossypolone disrupts the Musashi-numb RNA interaction and directly binds to the RBD1 of MSI1 protein. Gossypolone can be used for the research of cancer [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 4547-72-2. Pack Sizes: 1 mg. Product ID: HY-119734. | |
| Gosuranemab | Gosuranemab (BMS-986168) is a humanised IgG4 anti- tau monoclonal antibody. Gosuranemab binds to human N-terminal tau residues 15-22. Gosuranemab has the potential for the research of alzheimers disease (AD) [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: BMS-986168; IPN007; BIIB092. CAS No. 1788032-39-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99648. | |
| Gotistobart | Gotistobart (ONC-392) is a humanized anti-CTLA-4 antibody that confers immunotherapeutic effect by selective depletion of regulatory T cells (Treg) in the tumor microenvironment [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: ONC-392; BNT 316. CAS No. 2226344-78-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990042. | |
| Govorestat | Govorestat (AT-007) is an orally active brain-penetrant aldose reductase inhibitor with an IC 50 value of 100 pM. Govorestat has the potential for galactose-1-phosphate uridyl transferase deficiency research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AT-007. CAS No. 2170729-29-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-129586. | |
| GPCR agonist-2 | GPCR agonist-2 (Compound 5j) is a GPCR GPR109b (HM74) agonist, with a pEC 50 value of 6.51. GPCR agonist-2 can be used for research of lipid disorders [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 291528-35-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-47823. | |
| GPCR modulator-1 | GPCR modulator-1 is a negative allosteric modulator of GLP receptor. GPCR modulator-1 has the potential for type 2 diabetes research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1407592-99-7. Pack Sizes: 1 mg. Product ID: HY-124803. | |
| GPDA | GPDA(Glycylproline p-nitroanilide tosylate) is the substarate of X-Prolyl dipeptidyl-aminopeptidase in the enzyme assay. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: GPN; Glycylproline p-nitroanilide tosylate. CAS No. 65096-46-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16710. | |
| GPNA hydrochloride | GPNA hydrochloride is a well known substrate of the enzyme γ-glutamyltransferase ( GGT ). GPNA hydrochloride is a specific glutamine (Gln) transporter ASCT2 inhibitor. GPNA hydrochloride also inhibit Na + -dependent carriers, such as SNAT family (SNAT1/2/4/5), and the Na + -independent leucine transporters LAT1/2. GPNA reversibly induces apoptosis in A549 cells [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 67953-08-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-W011391. | |
| GPR139 agonist-2 | GPR139 agonist-2 (compound 20a) is a potent GPR139 agonist with an EC 50 of 24.7 nM. GPR139 agonist-2 rescues the social interaction deficits and alleviates cognitive deficits in murine schizophrenia models. GPR139 agonist-2 has the potential for antischizophrenia drug research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2983118-29-0. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-149651. | |
| GPR183-IN-2 | GPR183-IN-2 (compound 23) is a potent GPR183 inhibitor. GPR183-IN-2 inhibits Ca 2+ mobilization with an IC 50 value of 39.45 nM. GPR183-IN-2 has the potential for the research of cancer, autoimmune diseases, pain, and osteoporosis [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2924064-10-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-163796. | |
| GPR35 agonist 5 | GPR35 agonist 5 (3,5-dinitro-bisphenol A; compound 6) is a weak GPR35 agonist. GPR35 agonist 5 arrests CHO-S cells at the G1/Gophase [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2226201-24-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-149190. | |
| GPR55 agonist 3 | GPR55 agonist 3 (Compound 26) is a GPR55 agonist ( EC 50 : 0.239 nM, and 1.76 nM for hGPR55 and rGPR55). GPR55 agonist 3 induces β-arrestin recruitment to human GPR55 ( EC 50 : 6.2 nM) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3006105-44-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-156107. | |
| GQ-16 | GQ-16 is a moderate affinity ligand for the ligand-binding domain (LBD) of PPARγ , exhibiting a K i of 160 nM. GQ-16 is an effective inhibitor of Cdk5-mediated phosphorylation of PPAR&gamma. GQ-16 is a partial agonist of PPARγ with reduced adipogenic actions. GQ-16 promotes insulin Sensitization without weight gain [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 870554-67-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111254. | |
| GR 113808 | GR 113808 is a potent and highly selective 5-HT 4 receptor antagonist ( pK b = 8.8). GR 113808 shows 300-fold selectivity over 5-HT 1A , 5-HT 1B , 5-HT 2A , 5-HT 2C and 5-HT 3 receptors [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 144625-51-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103152. | |
| GR127935 hydrochloride | GR127935 hydrochloride is a potent and orally active 5-HT1D and 5-HT1B receptor antagonist with pKis of 8.5 for both isoforms. GR127935 hydrochloride has 100-fold selectivity for 5-HT1B/1D receptors over 5-HT1A, 5-HT2A, and 5-HT2C receptors. GR127935 hydrochloride can be used in neurological disease research [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 148642-42-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-100794. | |
| GR24 | (Rac)-GR24 (Strigolactone GR24) is a plant hormone analog. (Rac)-GR24 can mimic the natural germination stimulus of parasitic plant seeds, promoting seed germination in the absence of host plants, thereby reducing the number of parasitic seeds in the soil. (Rac)-GR24 can be used in agricultural research [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Strigolactone GR24. CAS No. 76974-79-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-129038. | |
| GR 55562 hydrochloride | GR 55562 hydrochloride is a selective 5-HT 1B receptor antagonist. GR 55562 hydrochloride can be used for the research of nerve disease [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 172854-55-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-W010869. | |
| GR 89696 | GR 89696 is a highly selective κ2 opioid receptor agonist with potential to prevent pruritus [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 126766-32-3. Pack Sizes: 10 mM * 1 mL; 5 mg. Product ID: HY-107747. | |
| Gramicidin | Gramicidin is an antimicrobial peptide assembling as channels in membranes and increasing their permeability towards cations. Uses: Scientific research. Group: Peptides. CAS No. 1405-97-6. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-P0163. | |
| Gramicidin A | Gramicidin A is a peptide component of gramicidin, an antibiotic mixture originally isolated from B. brevis. Gramicidin A is a highly hydrophobic channel-forming ionophore that forms channels in model membranes that are permeable to monovalent cations. Gramicidin A induces degradation of hypoxia inducible factor 1 α ( HIF-1α ) [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 11029-61-1. Pack Sizes: 5 mg. Product ID: HY-P2324. | |
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