MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Etilevodopa hydrochloride | Etilevodopa (L-Dopa ethyl ester) hydrochloride, an ethyl-ester proagent of Levodopa, is rapidly hydrolyzed to Levodopa and ethanol by nonspecific esterases in the gastrointestinal tract. Etilevodopa hydrochloride is used for the treatment of Parkinson disease (PD). Levodopa is the direct precursor of dopamine and is a suitable proagent as it facilitates CNS penetration and delivers dopamine [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: L-DOPA ethyl ester hydrochloride; Levodopa ethyl ester hydrochloride. CAS No. 39740-30-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116016A. |  |
| Etimicin sulfate | Etimicin (sulfate), a fourth-generation aminoglycoside antibiotic, is now widely clinically used due to its high efficacy and low toxicity. Uses: Scientific research. Group: Signaling pathways. CAS No. 362045-44-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0755. | |
| Etiocholanolone | Etiocholanolone (5β-Androsterone) is the excreted metabolite of testosterone and has anticonvulsant activity [1]. Etiocholanolone is a less potent neurosteroid positive allosteric modulator (PAM) of the GABA A receptor than its enantiomer form [2]. Uses: Scientific research. Group: Natural products. Alternative Names: 5β-Androsterone. CAS No. 53-42-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-113320. | |
| Etiracetam | Etiracetam (UCB 6474) is an acetylcholine agonist and a nootropic drug of the racetam family. Less active than its S-enantiomer Levetiracetam (UCB L059) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: UCB 6474. CAS No. 33996-58-6. Pack Sizes: 10 mM * 1 mL; 50 mg. Product ID: HY-B0106A. | |
| Etodolac | Etodolac (AY-24236) is a non-steroidal anti-inflammatory compound that is a non-selective inhibitor of COX (IC 50 =53.5 nM). Uses: Scientific research. Group: Signaling pathways. Alternative Names: AY-24236. CAS No. 41340-25-4. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-76251. | |
| Etofenamate | Etofenamate, a non-steroid anti-inflammatory agent ( NSAID ) and a non-selective COX inhibitor, possesses analgesic, anti-rheumatic, antipyretic and anti-inflammatory properties. Etofenamate is used in the research for osteoarthritis, arthritis and other inflammatory diseases [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 30544-47-9. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-17361. | |
| Etofenprox | Etofenprox is an orally active non-ester pyrethroid insecticide. Etofenprox induces toxicity against many pest insects, including Diptera rather than mammalian and fish. Etofenprox has a liver tumor-promoting activity in rats accompanied with microsomal ROS production increase. Etofenprox can be used in agricultural pest control and malaria research [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 80844-07-1. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-B0816. | |
| Etofibrate | Etofibrate is the ethandiol-1,2 diester of the nicotinic and clofibric acids. Etofibrate has been shown to be a potent hypolipidemic agent in animal and human. Uses: Scientific research. Group: Signaling pathways. CAS No. 31637-97-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-A0127. | |
| Etokimab | Etokimab (Antibody ANB 020) is a humanized monoclonal antibody that targets IL-33. Etokimab can be used for the research of atopic dermatitis [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Antibody ANB 020. CAS No. 2022981-44-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99018. | |
| Etomoxir | Etomoxir ((R)-(+)-Etomoxir) is an irreversible inhibitor of carnitine palmitoyltransferase 1a (CPT-1a), inhibits fatty acid oxidation (FAO) through CPT-1a and inhibits palmitate ?-oxidation in human, rat and guinea pig. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (R)-(+)-Etomoxir. CAS No. 124083-20-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-50202. | |
| Etomoxir sodium salt | Etomoxir((R)-(+)-Etomoxir) sodium salt is an irreversible inhibitor of carnitine palmitoyltransferase 1a ( CPT-1a ), inhibits fatty acid oxidation (FAO) through CPT-1a and inhibits palmitate β-oxidation in human, rat and guinea pig [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (R)-(+)-Etomoxir sodium salt. CAS No. 828934-41-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-50202A. | |
| Etonogestrel | Etonogestrel (3-Oxodesogestrel), a biologically active metabolite of progestin Desogestrel, binds with high affinity to progesterone receptors and estrogen receptors in the target organs [1]. Etonogestrel induce FKBP51 mRNA and protein expression in cultured human endometrial stromal cells (HESCs) [2]. Uses: Scientific research. Group: Natural products. Alternative Names: 3-Oxodesogestrel; 3-keto-Desogestrel. CAS No. 54048-10-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-B0652. | |
| Etoperidone | Etoperidone, an antidepressant agent, is an orally active serotonin and nor-adrenaline re-uptake antagonist. Etoperidone shows K d values of 36 nM, 38 nM, 85 nM, and 570 nM for 5-HT2 receptor , α1-adrenergic receptor , 5-HT1A receptor , and α2-adrenergic receptor , respectively [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 52942-31-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106617. | |
| Etoposide | Etoposide (VP-16; VP-16-213) is an anti-cancer chemotherapy agent. Etoposide inhibits topoisomerase II , thus stopping DNA replication. Etoposide induces cell cycle arrest, apoptosis and autophagy [1]. Uses: Scientific research. Group: Natural products. Alternative Names: VP-16; VP-16-213. CAS No. 33419-42-0. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg. Product ID: HY-13629. | |
| Etoposide phosphate | Etoposide phosphate (BMY-40481) is a potent anti-cancer chemotherapy agent and a selective topoisomerase II inhibitor to prevent re-ligation of DNA strands. Etoposide phosphate is the phosphate ester proagent of etoposide and is considered as active equivalent to Etoposide. Etoposide phosphate induces cell cycle arrest, apoptosis, and autophagy. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BMY-40481. CAS No. 117091-64-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13630. | |
| Etoricoxib | Etoricoxib (MK-0663) is a non steroidal anti-inflammatory agent, acting as a selective and orally active COX-2 inhibitor, with IC 50 s of 1.1 μM and 116 μM for COX-2 and COX-1 in human whole blood. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-0663; L-791456. CAS No. 202409-33-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15321. | |
| Etoxazole | Etoxazole (YI-5301) is an organofluorine insecticide widely used in agriculture. Etoxazole affects the nymphs, eggs, and larvae of spider mites by inhibiting chitin biosynthesis [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: YI-5301. CAS No. 153233-91-1. Pack Sizes: 10 mg. Product ID: HY-W059342. | |
| ETP-46464 | ETP-46464 is an effective mTOR and ATR inhibitor with IC50s of 0.6 and 14 nM, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1345675-02-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15521. | |
| Etrasimod | Etrasimod (APD334) is a potent, selective and orally available antagonist of the sphingosine-1-phosphate-1 ( S1P 1 ) receptor with an IC 50 value of 1.88 nM in CHO cells. Uses: Scientific research. Group: Signaling pathways. Alternative Names: APD334. CAS No. 1206123-37-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12789. | |
| Etravirine | Etravirine (R165335; TMC125) is a non-nucleoside reverse transcriptase inhibitor ( NNRTI ) used for the treatment of HIV. Uses: Scientific research. Group: Signaling pathways. Alternative Names: R165335; TMC125. CAS No. 269055-15-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-90005. | |
| Etretinate | Etretinate(Ro 10-9359) is a second-generation retinoid that has the potential for severe psoriasis treatment. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ro 10-9359. CAS No. 54350-48-0. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0797. | |
| Etripamil | Etripamil (MSP-2017) is a short-acting L-type calcium-channel antagonist, can be used for the research of Paroxysmal Supraventricular Tachycardia (PSVT). Etripamil (MSP-2017) slows atrioventricular nodal conduction and prolongs atrioventricular nodal refractory periods by inhibiting calcium ion influx through the calcium slow channels in the atrioventricular node cells [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MSP-2017; (-)-MSP-2017. CAS No. 1593673-23-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17611. | |
| Etrolizumab | Etrolizumab (rhuMAb Beta7) is a gut-selective, anti- β7 integrin monoclonal antibody. Etrolizumab is specific targeting of the β7 subunit of α4β7 and αEβ7 integrins with K i values of 18 nM and 1800 pM for Human α4β7 and Human αEβ7-293, respectively. Etrolizumab can be used in research of inflammatory bowel disease (IBD) [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: rhuMAb Beta7; RG7413; PRO145223. CAS No. 1044758-60-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9984. | |
| Etrumadenant | Etrumadenant (AB928) is an orally bioavailable, selective dual adenosine receptor (A2aR/A2bR) antagonist. Etrumadenant relieves adenosine-mediated immune suppression. Etrumadenant has immunomodulatory and antitumor activities [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AB928. CAS No. 2239273-34-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-129393. | |
| ETZ | ETZ (C3-CA-DTZ) is a promising luciferase substrate (prosubstrate) activatable in vivo by nonspecific esterase to enhance the brain delivery of the luciferin [1]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: C3-CA-DTZ. CAS No. 2989379-61-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145127. | |
| Etzadroxil | Etzadroxil (Ethyl 2-Ethylbutyrate) is a volatile ester compound. Sulopenem Etzadroxil is an orally available ester proagent form of Sulopenem, an antibiotic with broad-spectrum activities against Gram-positive and Gram-negative bacteria [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ethyl 2-Ethylbutyrate. CAS No. 2983-38-2. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-W127442. | |
| Eugenin | Eugenin is a chromone isolated from Peucedanum japonicum , with potent antiplatelet aggregation activity [1]. Uses: Scientific research. Group: Natural products. CAS No. 480-34-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-33351. | |
| Eugenol | Eugenol is an essential oil found in cloves with antibacterial, anthelmintic and antioxidant activity. Eugenol is shown to inhibit lipid peroxidation. Uses: Scientific research. Group: Natural products. CAS No. 97-53-0. Pack Sizes: 10 mM * 1 mL; 500 mg; 5 g. Product ID: HY-N0337. | |
| Eugenol acetate | Eugenol acetate (Eugenyl acetate) is an antibacterial, anticancer, anti-inflammatory and antioxidant. Eugenol acetate inhibits NF-κB and enhances the expression of p53 and p21 (WAF1). Eugenol acetate can prevent chemically induced skin cancer, inhibit cancer cell proliferation and induce apoptosis [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: Acetyleugenol. CAS No. 93-28-7. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-W014612. | |
| Eugenol acetate (Standard) | Eugenol acetate (Standard) is the analytical standard of Eugenol acetate. This product is intended for research and analytical applications. Eugenol acetate (Eugenyl acetate) is an antibacterial, anticancer, anti-inflammatory and antioxidant. Eugenol acetate inhibits NF-κB and enhances the expression of p53 and p21 (WAF1). Eugenol acetate can prevent chemically induced skin cancer, inhibit cancer cell proliferation and induce apoptosis [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. CAS No. 93-28-7. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-W014612R. | |
| EUK-134 | EUK-134, a synthetic superoxide dismutase and catalase mimetic, protects rat kidneys from ischemia-reperfusion-induced damage. EUK-134 is a superoxide dismutase ( SOD ) mimetics (SODm) with catalase activity. EUK-134 is a mitoprotective antioxidant. EUK-134 reduces the expression of NF-κB , MDA level, and protein carbonylation in H9C2 cells [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 81065-76-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-100594. | |
| Eupatilin | Eupatilin, a lipophilic flavonoid isolated from Artemisia argyi , is a PPARα agonist, and possesses anti-apoptotic, anti-oxidative and anti-inflammatory activities. Uses: Scientific research. Group: Natural products. CAS No. 22368-21-4. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg. Product ID: HY-N0783. | |
| Eupatolitin | Eupatoletin is a flavonol compound isolated from Eupatorium ligustrinum D.C. [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Eupatoletin. CAS No. 29536-44-5. Pack Sizes: 1 mg. Product ID: HY-N10886. | |
| Eupenifeldin | Eupenifeldin is pentacyclic bistropolone isolated from cultures of Eupenicillium brefeldianum ATCC 74184. Eupenifeldin is cytotoxic against the HCT-116 cell line. Eupenifeldin has the potential for the research of leukemia [1]. Uses: Scientific research. Group: Natural products. CAS No. 151803-45-1. Pack Sizes: 100 μg; 500 μg. Product ID: HY-119784. | |
| Eurycomanone | Eurycomanone could increases spermatogenesis by inhibiting the activity of phosphodiesterase and aromatase in steroidogenesis. Uses: Scientific research. Group: Natural products. Alternative Names: Pasakbumin A. CAS No. 84633-29-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-N5012. | |
| Euscaphic acid | Euscaphic acid, a DNA polymerase inhibitor, is a triterpene from the root of the R. alceaefolius Poir. Euscaphic inhibits calf DNA polymerase α (pol α) and rat DNA polymerase β (pol β) with IC 50 values of 61 and 108 μM [1]. Euscaphic acid induces apoptosis [2]. Uses: Scientific research. Group: Natural products. CAS No. 53155-25-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N2566. | |
| Evacetrapib | Evacetrapib is a potent and selective of CETP inhibitor, which inhibits human recombinant CETP protein ( IC 50 5.5 nM) and CETP activity in human plasma ( IC 50 36 nM) in vitro. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LY2484595. CAS No. 1186486-62-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13327. | |
| Evans Blue | Evans Blue (Direct Blue 53) is a potent inhibitor of L-glutamate uptake via the membrane bound excitatory amino acid transporter (EAAT). Evans Blue is a L-glutamate and kainate receptor -mediated currents inhibitor. Evans Blue has a strong affinity towards serum albumin, making it a high molecular weight protein tracer. Evans Blue is also used to study BBB (blood-brain barrier) permeability [1] [2]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Direct Blue 53; T-1824; C.I. 23860. CAS No. 314-13-6. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B1102. | |
| Evatanepag | Evatanepag (CP-533536) is a non-prostanoid, potent and selective EP 2 receptor agonist. Evatanepag can induce local bone formation in vivo. Evatanepag can be used in the research of fractures, bone defects, asthma [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CP-533536 free acid. CAS No. 223488-57-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14839. | |
| Evenamide | Evenamide (NW-3509) is an orally available voltage-gated sodium channel (VGSC) blocker ( K i =0.4 μM) for the research of schizophrenia. Evenamide shows efficacy in a broad spectrum of rodent models of psychosis, mania, depression, and aggressiveness [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NW-3509. CAS No. 1092977-61-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17612. | |
| Everolimus | Everolimus (RAD001) is a Rapamycin (HY-10219) derivative and a potent, selective and orally active mTOR1 inhibitor. Everolimus binds to FKBP-12 to generate an immunosuppressive complex. Everolimus inhibits tumor cells proliferation and induces cell apoptosis and autophagy. Everolimus has potent immunosuppressive and anticancer activities [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RAD001; SDZ-RAD. CAS No. 159351-69-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-10218. | |
| Everolimus-d4 | Everolimus-d 4 is the deuterium labeled Everolimus. Everolimus (RAD001) is a Rapamycin derivative and a potent, selective and orally active mTOR1 inhibitor. Everolimus binds to FKBP-12 to generate an immunosuppressive complex. Everolimus inhibits tumor cells proliferation and induces cell apoptosis and autophagy. Everolimus has potent immunosuppressive and anticancer activities[1][2]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: RAD001-d4; SDZ-RAD-d4. CAS No. 1338452-54-2. Pack Sizes: 500 μg. Product ID: HY-10218S. | |
| Evinacumab | Evinacumab (REGN1500) is a human anti- ANGPTL3 ( angiopoietin-like protein 3 ) monoclonal antibody (IgG4 class antibody). Evinacumab reduces plasma lipids in dyslipidemic mice by blocking ANGPTL3. Evinacumab can be used in studies of homozygous familial hypercholesterolaemia (HoFH), refractory hypercholesterolaemia (both familial and non-familial) and severe hypertriglyceridaemia [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: REGN1500. CAS No. 1446419-85-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P99194. | |
| Evixapodlin | Evixapodlin (GS-4224) is a human PD-1/PD-L1 protein/protein interaction inhibitor with an IC50 of 0.213 nM. Evixapodlin has anticancer and antiviral functions[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GS-4224; PD-1/PD-L1-IN 7. CAS No. 2374856-75-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-138407. | |
| Evobrutinib | Evobrutinib (M2951) is an orally active, potent, highly selective and irreversibly covalent BTK inhibitor, with an IC 50 of 8.9 nM. Evobrutinib (M2951) can be used for the research of autoimmune diseases [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: M2951; MSC2364447C. CAS No. 1415823-73-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101215. | |
| Evocalcet | Evocalcet (KHK7580) is an orally active calcium sensing receptor ( CaSR ) agonist. Evocalcet inhibits the secretion of parathyroid hormone (PTH) from parathyroid gland cells. Evocalcet can be used for the research of hyperparathyroidism [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KHK7580. CAS No. 870964-67-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17613. | |
| Evodenoson | Evodenoson is a selective agonist of the A 2A adenosine receptor. Evodenosons primary actions include reducing inflammatory responses, decreasing intestinal fluid secretion, edema, tissue damage, and neutrophil infiltration induced by Clostridium difficile toxin A. Evodenosons protective effect is achieved by reducing myeloperoxidase (MPO) and adenosine deaminase (ADA) activities, and by lowering the production of tumor necrosis factor-alpha (TNF-α) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ATL 313; DE 112. CAS No. 844873-47-8. Pack Sizes: 1 mg. Product ID: HY-105017. | |
| Evodiamine | Evodiamine is an alkaloid isolated from the fruit of Evodia rutaecarpa Bentham with diverse biological activities including anti-inflammatory, anti-obesity, and antitumor. Uses: Scientific research. Group: Natural products. Alternative Names: (+)-Evodiamine; d-Evodiamine. CAS No. 518-17-2. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 250 mg. Product ID: HY-N0114. | |
| Evofosfamide | Evofosfamide (TH-302) is a hypoxia -activated proagent with IC 50 of 10 μM and 1000 μM in hypoxia (N 2 ) and normoxia (21% O 2 ), respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TH-302. CAS No. 918633-87-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10535. | |
| Evogliptin tartrate | Evogliptin (DA-1229) tartrate is an orally active DPP4 inhibitor with significant and sustained hypoglycaemic effects in mouse models. Evogliptin tartrate also inhibits the production of inflammatory and fibrotic signals in hepatocytes by inducing autophagy. Evogliptin tartrate can be used in studies of type 2 diabetes, osteoporosis, renal impairment and chronic liver inflammation [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DA-1229 tartrate. CAS No. 1222102-51-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-117985B. | |
| Evolocumab | Evolocumab (AMG 145) is a human monoclonal antibody that inhibits PCSK9. Evolocumab is used in the study of hypercholesterolemia and atherosclerotic cardiovascular disease. Evolocumab binds to circulating PCSK9 protein and inhibits its binding to LDLR. Evolocumab has antioxidant and cytoprotective activities against H 2 O 2 -induced oxidative damage to endothelial cells. Evolocumab may also negatively regulate activation of the TLR-4/NF-κB signaling pathway to prevent inflammation [1] [2] [3]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: AMG 145. CAS No. 1256937-27-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9930. | |
| Evunzekibart | Evunzekibart (ATOR-1017) is an Fc-γ receptor conditional 4-1BB agonist and IgG4-type antibody. Evunzekibart can be used as monotherapy or in combination with anti-PD1 to exert anticancer activity. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: ATOR-1017. CAS No. 2639688-77-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990067. | |
| Evuzamitide | Evuzamitide is a diagnostic imaging agent. Evuzamitide as a pan-amyloid radiotracer binding to amyloid deposits from multiple amyloidogenic proteins. Evuzamitide can be used for the research of early diagnosis of amyloid cardiomyopathy (CMP) and monitoring [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 1420048-58-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P10023. | |
| EX229 | EX229, a Benzimidazole derivative, is a potent and allosteric activator of AMP-activated protein kinase (AMPK), with Kds of 0.06 ?M, 0.06 ?M and 0.51 ?M for ?1?1?1, ?2?1?1 and ?1?2?1 in biolayer interferometry, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1219739-36-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-112769. | |
| Ex26 | Ex26 (S1P1-IN-Ex26) is a potent and selective sphingosine 1-phosphate receptor 1 ( S1P 1 ) antagonist ( IC 50=0.93 nM). Ex26 shows >3,000-fold selectivity for S1P 1 over other Sphingosine 1-phosphate receptors. Ex26 can be used in experimental autoimmune encephalomyelitis reseach [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: S1P1-IN-Ex26. CAS No. 1233332-37-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-117213. | |
| Exaluren disulfate | Exaluren (ELX-02) disulfate is an investigational, advanced synthetic eukaryotic ribosome selective glycoside (ERSG). Exaluren disulfate is being developed as a therapy for genetic diseases caused by nonsense mutations[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ELX-02 disulfate; NB-124 disulfate. CAS No. 2244622-33-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-114231B. | |
| Exarafenib | Exarafenib (RAF/KIN_2787) is an orally-available, selective pan-RAF inhibitor. Exarafenib is effective in RAF-dependent cancers, including all classes of BRAF alterations. Exarafenib suppresses MAPK signaling in RAF-dependent melanoma cell lines. Exarafenib has anticancer activity[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RAF/KIN_2787. CAS No. 2639957-39-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-147268. | |
| Exatecan | Exatecan (DX-8951) is a DNA topoisomerase I inhibitor, with an IC 50 of 2.2 μM (0.975 μg/mL), and can be used in cancer research. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DX-8951. CAS No. 171335-80-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13631. | |
| Exatecan-d5 mesylate | Exatecan-d5 (DX8951f-d5) mesylate is deuterium labeled Exatecan mesylate (HY-13631A). Exatecan mesylate is a DNA topoisomerase I inhibitor, with an IC50 of 2.2 ?M (0.975 ?g/mL). Exatecan mesylate can be used in cancer research[1]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: DX8951f-d5; Deuterated labeled Exatecan mesylate. CAS No. 2819276-88-3. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13631AS. | |
| Exatecan mesylate | Exatecan mesylate (DX8951f) is a DNA topoisomerase I inhibitor, with an IC 50 of 2.2 μM (0.975 μg/mL). Exatecan mesylate can be used in cancer research. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DX8951f. CAS No. 169869-90-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-13631A. | |
| Exatecan (mesylate) (GMP) | Exatecan mesylate (DX8951f ) GMP is a GMP-class Exatecan (HY-13631). Exatecan is a DNA topoisomerase I inhibitor, with an IC50 of 2.2 ?M (0.975 ?g/mL), and can be used in cancer research[1][2][3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DX8951f (GMP). CAS No. 169869-90-3. Pack Sizes: 10 mg; 50 mg; 100 mg. Product ID: HY-13631AG. | |
| Exatecan (Standard) | Exatecan (Standard) is the analytical standard of Exatecan. This product is intended for research and analytical applications. Exatecan (DX-8951) is a DNA topoisomerase I inhibitor, with an IC50 of 2.2 ?M (0.975 ?g/mL), and can be used in cancer research. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DX-8951 (Standard). CAS No. 171335-80-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13631R. | |
| Exemestane | Exemestane (FCE 24304) is a selective, irreversible and orally active steroidal aromatase inhibitor with IC 50 s of 30 nM and 40 nM for human placenta l and rat ovarian aromatase , respectively. Exemestane can be used for hormone-dependent breast cancer research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FCE 24304; EXE. CAS No. 107868-30-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13632. | |
| Exemestane (Standard) | Exemestane (Standard) is the analytical standard of Exemestane. This product is intended for research and analytical applications. Exemestane (FCE 24304) is a selective, irreversible and orally active steroidal aromatase inhibitor with IC 50 s of 30 nM and 40 nM for human placenta l and rat ovarian aromatase , respectively. Exemestane can be used for hormone-dependent breast cancer research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FCE 24304(Standard); EXE (Standard). CAS No. 107868-30-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-13632R. | |
| Exendin-3 | Exendin-3 is a biologically active peptides isolated from venoms of the Gila monster lizards, Heloderma horridurn. Uses: Scientific research. Group: Peptides. CAS No. 130357-25-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P1543. | |
| Exendin-4 | Exendin-4 (Exenatide), a 39 amino acid peptide, is a long-acting glucagon-like peptide-1 receptor agonist with an IC 50 of 3.22 nM. Uses: Scientific research. Group: Peptides. Alternative Names: Exenatide. CAS No. 141758-74-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-13443. | |
| Exendin-4 acetate | Exendin-4 acetate (Exenatide acetate), a 39 amino acid peptide, is a long-acting glucagon-like peptide-1 receptor agonist with an IC 50 of 3.22 nM. Uses: Scientific research. Group: Peptides. Alternative Names: Exenatide acetate. CAS No. 914454-01-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-13443A. | |
| Exendin(9-39) amide | Exendin(9-39) amide (Avexitide) is a glucagon-like peptide-1 ( GLP-1 ) antagonist that competes with endogenous GLP-1 for binding to GLP-1 receptors, thereby antagonizing the effects of excess GLP-1 secretion. Exendin(9-39) amide can be used to study postoperative hypoglycemia (PBH) [1]. Uses: Scientific research. Group: Peptides. Alternative Names: Avexitide. CAS No. 133514-43-9. Pack Sizes: 500 μg; 1 mg; 5 mg. Product ID: HY-P0264. | |
| Exicorilant | Exicorilant (CORT 125281) is a selective and oral active glucocorticoid receptor (GR) antagonist, with a Ki value of 7 nM[1]. Exicorilant (CORT 125281) has potential to overcome adiposity, glucose intolerance and dyslipidaemia[2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CORT 125281. CAS No. 1781244-77-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-117880. | |
| Exisulind | Exisulind is an inactive metabolite of the nonsteroidal, anti-inflammatory agent sulindac [1]. Exisulind inhibits aldose reductase with an IC 50 of 367 nM in vitro and may contribute to the beneficial pharmacological effects of sulindac on type 2 diabetic complications [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 59864-04-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-13633. | |
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