MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
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ZSTK474
ZSTK474 is an ATP-competitive pan-class I PI3K inhibitor with IC 50 s of 16 nM, 44 nM, 4.6 nM and 49 nM for P&Lota;3Κα, PI3Kβ, PI3Kδ and PI3Kγ, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 475110-96-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-50847.
ZT55
ZT55 is an orally active and highly-selective JAK2 inhibitor with an IC 50 value of 0.031 μM. ZT55 inhibits the proliferation of JAK2 V617F -expressing HEL cell lines and induces apoptosis and cycle arrest. ZT-55 also effectively inhibits the growth of HEL xenograft tumours in a mice model. ZT-55 can be used in studies of myeloproliferative neoplasms, polycythemia vera and primary thrombocythemia [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2138488-38-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-124727.
Z-Tyr-OH
Z-Tyr-OH is a tyrosine derivative [1]. Uses: Scientific research. Group: Peptides. CAS No. 1164-16-5. Pack Sizes: 25 g; 100 g. Product ID: HY-W007931.
Zuclomiphene citrate
Zuclomiphene citrate is a cis isomer of Clomiphene citrate. Zuclomiphene citrate has an antiestrogenic effect and can inhibit the secretion of luteinizing hormone (LH) more than the trans isomer. Zuclomiphene citrate is also an orally active hypocholesterolemic agent [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 7619-53-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-B1617A.
Zuclopenthixol
Zuclopenthixol ((Z)-Clopenthixol) is a thioxanthene derivative which acts as a mixed dopamine D1/D2 receptor antagonist [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (Z)-Clopenthixol. CAS No. 53772-83-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-A0163.
Z-VAD
Z-VAD is a competitive, irreversible pan- caspase inhibitor. Z-VAD inhibits all 10 caspases, except for caspase-2 which is only weakly inhibited. Z-VAD decreases radiation-induced apoptosis. Z-VAD induces both autophagy and necrosis in irradiated MDA-MB-231 and H460 mouse xenografts. Z-VAD with radiation produces a significant tumor growth delay and shows dramatic antiangiogenic effect in cancer xenograft [1]. Uses: Scientific research. Group: Peptides. CAS No. 162852-62-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-164388.
Z-Val-Val-Arg-AMC
Z-Val-Val-Arg-AMC is a fluorescent peptide substrate that can be used to test the activity of cathepsins [1]. Uses: Scientific research. Group: Peptides. CAS No. 124485-41-2. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-137367.
Z-VEID-FMK
Z-VEID-FMK (Z-VE(OMe)ID(OMe)-FMK) is a selective and irreversible caspase-6 peptide inhibitor. Z-VEID-FMK alleviates the drug-induced augmentation of caspase-6 activity, DNA fragmentation, and cell apoptosis [1] [2]. Uses: Scientific research. Group: Peptides. Alternative Names: Z-VE(OMe)ID(OMe)-FMK. CAS No. 210344-96-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P1007.
Zymosan A
Zymosan A (Zymosan A from Saccharomyces cerevisiae) is a TLR2 agonist, that targeting TLRs can prevent and suppress IR-induced intestinal injury. Zymosan A exhibits a significant radioprotective effect, and protects IR-induced intestinal injury in mice. Zymosan A promotes the regeneration of intestinal stem cells (ISCs), after IR injury [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Zymosan A from Saccharomyces cerevisiae. CAS No. 58856-93-2. Pack Sizes: 50 mg; 100 mg. Product ID: HY-W250113.
Zymostenol
Zymostenol (5a-Cholest-8-en-3b-ol) is a late-stage precursor in the biosynthesis of cholesterol. Zymostenol is a RORγ agonist ( EC 50 : 1 μM) [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 5a-Cholest-8-en-3b-ol. CAS No. 566-97-2. Pack Sizes: 1 mg. Product ID: HY-113345.
Zymostenol-d7
Zymostenol-d 7 is deuterium labeled 5a-Cholest-8-en-3b-ol. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: 5a-Cholest-8-en-3b-ol-d7. CAS No. 2260669-19-8. Pack Sizes: 1 mg. Product ID: HY-113345S.
Zymosterol
Zymosterol is a Cholesterol (HY-N0322) biosynthesis metabolite. Zymosterol, a precursor of Cholesterol, is found mostly in the plasma membrane. Zymosterol circulates within the cell [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 128-33-6. Pack Sizes: 1 mg; 5 mg. Product ID: HY-114297.
ZZW-115 hydrochloride
ZZW-115 hydrochloride is a potent NUPR1 inhibitor, with a K d of 2.1 μM. ZZW-115 hydrochloride induces tumor cell death by necroptosis and apoptosis. Anticancer activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 10122-45-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111838A.