MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Safimaltib | Safimaltib (JNJ-67856633) is an orally active, first-in-class, potent, selective and allosteric MALT1 protease inhibitor. Safimaltib in some cases lead to tumor stasis[1][2][3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: JNJ-67856633. CAS No. 2230273-76-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139399. |  |
| Safinamide | Safinamide is a potent, selective, and reversible monoamine oxidase B (MAO-B) inhibitor ( IC 50 =0.098 μM) over MAO-A (IC 50 =580 μM) [1]. Safinamide also blocks sodium channels and modulates glutamate (Glu) release, showing a greater affinity at depolarized ( IC 50 =8 μM) than at resting ( IC 50 =262 μM) potentials. Safinamide has neuroprotective and neurorescuing effects and can be used for the study of parkinson disease, ischemia stroke etc.al [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FCE 26743; EMD 1195686. CAS No. 133865-89-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-70057. | |
| Safinamide mesylate | Safinamide (FCE 26743; EMD 1195686) mesylate is a potent, selective, and reversible monoamine oxidase B (MAO-B) inhibitor ( IC 50 =0.098 μM) over MAO-A (IC 50 =580 nM) [1]. Safinamide mesylate also blocks sodium channels and modulates glutamate (Glu) release, showing a greater affinity at depolarized ( IC 50 =8 μM) than at resting ( IC 50 =262 μM) potentials. Safinamide mesylate has neuroprotective and neurorescuing effects and can be used for the study of parkinson disease, ischemia stroke et.al [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FCE 26743 mesylate; EMD 1195686 mesylate. CAS No. 202825-46-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-70057A. | |
| SAFit2 | SAFit2 is a highly potent, highly selective FK506-binding protein 51 (FKBP51) inhibitor with a Ki of 6 nM and also enhances AKT2-AS160 binding[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1643125-33-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-102080. | |
| Safranal | Safranal is an orally active main component of Saffron ( Crocus sativus ) and is responsible for the unique aroma of this spice. Safranal has neuroprotective and anti-inflammatory effects and has the potential for Parkinsons disease research [1]. Uses: Scientific research. Group: Natural products. CAS No. 116-26-7. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-N7560. | |
| Safranin | Safranin (Safranin T) is an important and classical phenazinium dye. Safranin has been extensively used in the academic field as a spectroscopic probe and indicator. Safranin possesses a planar structure and cationic charge. Safranin can readily intercalate into biological macromolecules, including DNA and proteins. Safranin has antibacterial effects against gram-positive bacteria ( S. aureus ). Safranin can be used as a redox indicator in the determination of metal ion concentration [1] [2] [3] [4]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: Safranine T. CAS No. 477-73-6. Pack Sizes: 1 g; 5 g. Product ID: HY-D0215. | |
| SAG | SAG is a potent Smoothened (Smo) receptor agonist ( EC 50 =3 nM; K d =59 nM). SAG activates the Hedgehog signaling pathway and counteracts Cyclopamine (HY-17024) inhibition of Smo [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 912545-86-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12848. | |
| SAG dihydrochloride | SAG dihydrochloride is a potent Smoothened (Smo) receptor agonist ( EC 50 =3 nM; K d =59 nM). SAG dihydrochloride activates the Hedgehog signaling pathway and counteracts Cyclopamine (HY-17024) inhibition of Smo [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2702366-44-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-12848C. | |
| SAG hydrochloride | SAG hydrochloride is a potent Smoothened (Smo) receptor agonist ( EC 50 =3 nM; K d =59 nM). SAG hydrochloride activates the Hedgehog signaling pathway and counteracts Cyclopamine (HY-17024) inhibition of Smo [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2095432-58-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-12848B. | |
| SAG (Standard) | SAG (Standard) is the analytical standard of SAG. SAG is a potent Smoothened (Smo) receptor agonist ( EC 50 =3 nM; K d =59 nM). SAG activates the Hedgehog signaling pathway and counteracts Cyclopamine (HY-17024) inhibition of Smo [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 912545-86-9. Pack Sizes: 1 mg; 5 mg. Product ID: HY-12848R. | |
| SAH | SAH (S-Adenosylhomocysteine) is an amino acid derivative and a modulartor in several metabolic pathways. It is an intermediate in the synthesis of cysteine and adenosine [1]. SAH is an inhibitor for METTL3-METTL14 heterodimer complex ( METTL3-14 ) with an IC 50 of 0.9 μM [2]. Uses: Scientific research. Group: Natural products. Alternative Names: SAH (S-Adenosylhomocysteine). CAS No. 979-92-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19528. | |
| SAH-SOS1A TFA | SAH-SOS1A TFA is a peptide-based SOS1/KRAS protein interaction inhibitor. SAH-SOS1A TFA binds to wild-type and mutant KRAS (G12D, G12V, G12C, G12S, and Q61H) with nanomolar affinity ( EC 50 =106-175 nM). SAH-SOS1A TFA directly and independently blocks nucleotide association. SAH-SOS1A TFA impairs KRAS-driven cancer cell viability and exerts its effects by on-mechanism blockade of the ERK-MAPK phosphosignaling cascade downstream of KRAS [1]. Uses: Scientific research. Group: Peptides. CAS No. 2896737-31-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P2265A. | |
| SAICAR | SAICAR is an intermediate of de novo purine nucleotide biosynthesis, activates pyruvate kinase isoform M2 (PKM2) in an isozyme-selective manner, with an EC50 of 0.3 mM. SAICAR stimulates PKM2 and promotes cancer cell survival in glucose-limited conditions[1][2]. Uses: Scientific research. Group: Natural products. CAS No. 3031-95-6. Pack Sizes: 10 mM * 1 mL; 500 ?g; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-126585. | |
| Saikosaponin B2 | Saikosaponin B2 is an active component from Bupleurum chinensis root, acts as an entry inhibitor against HCV infection [1]. Anti-cancer activity [2]. Uses: Scientific research. Group: Natural products. CAS No. 58316-41-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 20 mg. Product ID: HY-N0248. | |
| Saikosaponin C | Saikosaponin C is a bioactive component found in radix bupleuri , targets amyloid beta and tau in Alzheimer's disease. Saikosaponin C inhibits the secretion of both Aβ1-40 and Aβ1-42, and suppresses abnormal tau phosphorylation, but shows no effect on BACE1 activity and expression [1]. Uses: Scientific research. Group: Natural products. CAS No. 20736-08-7. Pack Sizes: 1 mg; 5 mg; 10 mg; 20 mg. Product ID: HY-N0249. | |
| sAJM589 | sAJM589 is a Myc inhibitor which potently disrupts the Myc-Max heterodimer with an IC50 of 1.8 ?M[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2089-82-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122683. | |
| Sakuranetin | Sakuranetin is a cherry flavonoid phytoalexin, shows strong antifungal activity [1]. Sakuranetin has anti-inflammatory and antioxidative activities. Sakuranetin ameliorates LPS-induced acute lung injury [2]. Uses: Scientific research. Group: Natural products. CAS No. 2957-21-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-N3006. | |
| Salazopyridazine | Salazopyridazine is an antibacterial agent. Salazopyridazine shows activities against ulcerative colitis. Salazopyridazine can be used for the research of rheumatic diseases [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 22933-72-8. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-145455. | |
| Salbutamol | Salbutamol (Albuterol) is a short-acting beta-2 adrenergic receptor agonist with oral activity. Salbutamol promotes tumorigenesis of gastric cancer cells through the β2-AR/ERK/EMT pathway. Salbutamol is used to study bronchospasms caused by asthma and chronic obstructive pulmonary disease (COPD) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Albuterol; AH-3365. CAS No. 18559-94-9. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B1037. | |
| Salbutamol-d9 | Salbutamol-d 9 is the deuterium labeled Salbutamol. Salbutamol is a short-acting β2-adrenergic receptor agonist used for the relief of bronchospasm in conditions such as asthma and chronic obstructive pulmonary disease (COPD). Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: Albuterol-d9; AH-3365-d9. CAS No. 1173021-73-2. Pack Sizes: 1 mg. Product ID: HY-B1037S2. | |
| Salbutamol hemisulfate | Salbutamol Hemisulfate (Albuterol hemisulfate) is a short-acting beta2-adrenoceptor agonist. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Albuterol hemisulfate; AH-3365 hemisulfate. CAS No. 51022-70-9. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0436. | |
| Salcaprozate sodium | Salcaprozate sodium (SNAC), an oral absorption promoter, and has the potential as a delivery agent for oral forms of heparin and insulin. Salcaprozate sodium could increase passive transcellular permeation across small intestinal epithelia based on increased lipophilicity arising from non-covalent macromolecule complexation[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SNAC. CAS No. 203787-91-1. Pack Sizes: 10 mM * 1 mL; 250 mg; 500 mg; 1 g. Product ID: HY-114299. | |
| Salermide | Salermide is an inhibitor of Sirt1 and Sirt2 ; can cause strong cancer-specific apoptotic cell death. Uses: Scientific research. Group: Signaling pathways. CAS No. 1105698-15-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101073. | |
| Salicin | Salicin is a natural COX inhibitor. Uses: Scientific research. Group: Natural products. Alternative Names: D-(-)-Salicin; Salicoside. CAS No. 138-52-3. Pack Sizes: 10 mM * 1 mL; 5 g; 10 g. Product ID: HY-N0149. | |
| Salicyl alcohol | Salicyl alcohol is used as an intermediate in pharmaceuticals, fragrances, and pesticides. Uses: Scientific research. Group: Natural products. Alternative Names: 2-Hydroxybenzyl alcohol; Saligenin. CAS No. 90-01-7. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-B1419. | |
| Salicylaldoxime | Salicylaldoxime is an organic compound, that has been used as a reagent for the gravimetric determination and separation of Cooper, Nickel, Palladium, Lead, Bismuth and Zine. The copper complex of Salicylaldoxime has anticancer activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 94-67-7. Pack Sizes: 25 g; 50 g. Product ID: HY-D0216. | |
| Salicylamide | Salicylamide is an inhibitor of microsomal UDP-glucuronosyltransferase. Salicylamide is an analgesic and anti-pyretic agent. Uses: Scientific research. Group: Natural products. Alternative Names: 2-Hydroxybenzamide. CAS No. 65-45-2. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 10 g. Product ID: HY-B0811. | |
| Salicylhydroxamic acid | Salicylhydroxamic acid (2-Hydroxybenzohydroxamic acid; N,2-Dihydroxybenzamide) is a biochemical reagent that can be used as a biological material or organic compound for life science related research [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: 2-Hydroxybenzohydroxamic acid; N,2-Dihydroxybenzamide. CAS No. 89-73-6. Pack Sizes: 10 mM * 1 mL; 25 g. Product ID: HY-18721. | |
| Salicylic acid | Salicylic acid (2-Hydroxybenzoic acid) inhibits cyclo-oxygenase-2 ( COX-2 ) activity independently of transcription factor (NF-κB) activation [1]. Uses: Scientific research. Group: Natural products. Alternative Names: 2-Hydroxybenzoic acid. CAS No. 69-72-7. Pack Sizes: 10 mM * 1 mL; 500 mg; 10 g; 50 g. Product ID: HY-B0167. | |
| Salicylic acid (Standard) | Salicylic acid (Standard) is the analytical standard of Salicylic acid. This product is intended for research and analytical applications. Salicylic acid (2-Hydroxybenzoic acid) inhibits cyclo-oxygenase-2 ( COX-2 ) activity independently of transcription factor (NF-κB) activation [1]. Uses: Scientific research. Group: Natural products. Alternative Names: 2-Hydroxybenzoic acid (Standard). CAS No. 69-72-7. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-B0167R. | |
| Salicyluric acid | Salicyluric acid is an endogenous metabolite. Uses: Scientific research. Group: Natural products. CAS No. 487-54-7. Pack Sizes: 10 mM * 1 mL; 100 mg; 250 mg. Product ID: HY-113295. | |
| Salidroside | Salidroside (Rhodioloside) is a prolyl endopeptidase inhibitor. Salidroside alleviates cachexia symptoms in mouse models of cancer cachexia via activating mTOR signalling. Salidroside protects dopaminergic neurons by enhancing PINK1/Parkin-mediated mitophagy. Uses: Scientific research. Group: Natural products. Alternative Names: Rhodioloside. CAS No. 10338-51-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-N0109. | |
| Salinomycin | Salinomycin (Procoxacin), a polyether potassium ionophore antibiotic, selectively inhibits the growth of gram-positive bacteria. Salinomycin is a potent inhibitor of Wnt/β-catenin signaling, blocks Wnt-induced LRP6 phosphorylation. Salinomycin shows selective activity against human cancer stem cells [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Procoxacin. CAS No. 53003-10-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-15597. | |
| Salinomycin sodium salt | Salinomycin sodium salt (Salinomycin sodium), an antibiotic potassium ionophore, is a potent inhibitor of Wnt/?-catenin signaling. Salinomycin sodium salt acts on the Wnt/Fzd/LRP complex, blocks Wnt-induced LRP6 phosphorylation, and causes degradation of the LRP6 protein. Salinomycin sodium salt shows selective activity against human cancer stem cells[1][2][3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Salinomycin sodium; Sodium salinomycin. CAS No. 55721-31-8. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-17439. | |
| Salipurpin | Salipurpin (Apigenin 5-glucoside) is a flavonoid compound isolated from the branches and leaves of Cephalotaxus fortunei , which has certain anti-inflammatory activity [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Apigenin 5-glucoside. CAS No. 28757-27-9. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N2883. | |
| Salirasib | Salirasib is a Ras inhibitor that inhibits specifically both oncogenically activated Ras and growth factor receptor-mediated Ras activation, resulting in the inhibition of Ras-dependent tumor growth. Uses: Scientific research. Group: Signaling pathways. Alternative Names: S-Farnesylthiosalicylic acid; Farnesyl Thiosalicylic Acid; FTS. CAS No. 162520-00-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14754. | |
| S-Allyl-L-cysteine | S-Allyl-L-cysteine, one of the organosulfur compounds found in AGE, possess various biological effects including neurotrophic activity, anti-cancer activity, anti-inflammatory activity. Uses: Scientific research. Group: Natural products. CAS No. 21593-77-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W013573. | |
| Salmeterol | Salmeterol (GR33343X) is a potent and selective human β2 adrenoceptor agonist. Salmeterol shows potent stimulation of cAMP accumulation in CHO cells expressing human β2, β1 and β3 adrenoceptors with pEC 50 s of 9.6, 6.1, and 5.9, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GR33343X. CAS No. 89365-50-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14302. | |
| Salmeterol-d3 | Salmeterol-d 3 is a deuterium labeled Salmeterol. Salmeterol is a potent and selective human β2 adrenoceptor agonist. Salmeterol shows potent stimulation of cAMP accumulation in CHO cells expressing human β2, β1 and β3 adrenoceptors with pEC50s of 9.6, 6.1, and 5.9, respectively[1]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 497063-94-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-135119. | |
| Salmeterol xinafoate | Salmeterol (GR 33343X) xinafoate is a potent and selective human β2 adrenoceptor agonist. Salmeterol shows potent stimulation of cAMP accumulation in CHO cells expressing human β2, β1 and β3 adrenoceptors with pEC 50 s of 9.6, 6.1, and 5.9, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GR 33343X xinafoate. CAS No. 94749-08-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17453. | |
| Salsalate | Salsalate is a potent antirheumatic drug with oral activity that reduces irritation during gastric absorption and avoids direct inhibition of cyclooxygenase. Salsalate not only has significant anti-inflammatory effects, but also reduces blood sugar levels, improves insulin resistance, and reduces the expression of cytokines. Salsalate can protect mice from metabolic disorders caused by high-fat diet and effectively improve the symptoms of type 2 diabetes, atherosclerosis and non-alcoholic steatohepatitis [1] [2 ] [3] [4] [5] [6]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Salicylsalicylic acid; Disalicylic acid. CAS No. 552-94-3. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-B1245. | |
| Salubrinal | Salubrinal is a cell-permeable and selective inhibitor of eIF2α dephosphorylation [1]. Salubrinal acts as a dual-specificity phosphatase 2 ( Dusp2 ) inhibitor and suppresses inflammation in anti-collagen antibody-induced arthritis [2]. Salubrinal has antiviral activity against HSV-1 and inhibits dephosphorylation of eIF2α mediated by the HSV-1 protein ICP34.5 [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 405060-95-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15486. | |
| Salvianolic acid A | Salvianolic acid A could protect the blood brain barrier through matrix metallopeptidase 9 (MMP-9) inhibition and anti-inflammation. Uses: Scientific research. Group: Natural products. CAS No. 96574-01-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-N0318. | |
| Salvianolic acid B | Salvianolic acid B is an active ingredient of Salvia miltiorrhiza, which has been widely applied in China for the management of various microcirculation-related disorders, such as cardiovascular disease, cerebrovascular disease, and diabetic vascular complication. Uses: Scientific research. Group: Natural products. Alternative Names: Lithospermic acid B. CAS No. 121521-90-2. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-N1362. | |
| Salvianolic acid C | Salvianolic acid C is a noncompetitive Cytochrome P4502C8 (CYP2C8) inhibitor and a moderate mixed inhibitor of Cytochrome P45022J2 (CYP2J2), with Kis of 4.82 ?M and 5.75 ?M for CYP2C8 and CYP2J2, respectively. Uses: Scientific research. Group: Natural products. CAS No. 115841-09-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0319. | |
| Salvianolic acid D | Salvianolic acid D, isolated from Salvia miltiorrhiza , is a potential antiplatelet activity compound [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 142998-47-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N0320. | |
| Salvigenin | Salvigenin is a natural polyphenolic compound, with neuroprotective effect. Salvigenin has antitumor cytotoxic and immunomodulatory properties. Salvigenin inhibits H 2 O 2 -induced cell apoptosis [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Psathyrotin. CAS No. 19103-54-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-N1318. | |
| Salvinorin B | Salvinorin B is the metabolite produced by Salvia divinorum. Salvinorin B is also the main metabolite of Salvinorin A in rhesus monkey blood [1]. Uses: Scientific research. Group: Natural products. CAS No. 92545-30-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-110252. | |
| Samalizumab | Samalizumab (ALXN 6000) is a humanized monoclonal antibody that specifically binds to CD200 and blocks its ligation to the CD200 receptor (CD200R). Samalizumab can be used for multiple myeloma and B-cell chronic lymphocytic leukemia research [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: ALXN 6000. CAS No. 1073059-33-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99400. | |
| Samatasvir | Samatasvir (IDX71) is a potent, orally active NS5A inhibitor of HCV replication. Samatasvir is effective and selective against infectious HCV and replicons, with EC 50 s falling within a tight range of 2 to 24 pM in genotype 1 through 5 replicons [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: IDX719; IDX18719. CAS No. 1312547-19-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16784. | |
| Samelisant | Samelisant (SUVN-G3031) is a potent and selective histamine H3 receptor (H3R) inverse agonist with good brain penetration and oral bioavailability. Samelisant has a similar binding affinity towards human (hH3R; K i =8.7 nM) and rat (rH3R;K i =9.8 nM) H3R indicating no inter-species differences. Samelisant can be used for the research of sleep-related disorders [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SUVN-G3031. CAS No. 1394808-20-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-120124. | |
| Samidorphan | Samidorphan (ALKS-33) is an orally active opioid system modulator that has a high affinity for binding with μ?opioid, κ?opioid, and δ?opioid receptors. Samidorphan acts as an antagonist at μ?opioid receptors and acts as a partial agonist at k-opioid and δ?opioid receptors. Samidorphan primarily acts as an opioid receptor antagonist in vivo [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ALKS-33; RDC-0313. CAS No. 852626-89-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-123689. | |
| Samotolisib | Samotolisib (LY3023414) potently and selectively inhibits class I PI3K isoforms, DNA-PK, and mTORC1/2 with IC50s of 6.07 nM, 77.6 nM, 38 nM, 23.8 nM, 4.24 nM and 165 nM for PI3K?, PI3K?, PI3K?, PI3K?, DNA-PK and mTOR, respectively. Samotolisib potently inhibits mTORC1/2 at low nanomolar concentrations[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LY3023414. CAS No. 1386874-06-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12513. | |
| (S)-AMPA | (S)-AMPA (L-AMPA), an active S-enantiomer of AMPA, is a potent and selective AMPA receptor agonist [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: L-AMPA. CAS No. 83643-88-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-100815A. | |
| Samrotamab | Samrotamab is a humanized IgG1-κ chimeric antibody targeting LRRC15 [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: PR-1498487. CAS No. 2052591-32-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99899. | |
| SAMS | SAMS peptide is a specific substrate for the AMP-activated protein kinase ( AMPK ). Uses: Scientific research. Group: Peptides. CAS No. 125911-68-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P0136. | |
| Samuraciclib hydrochloride | Samuraciclib hydrochloride (CT7001 hydrochloride) is a potent, selective, ATP-competitive and orally active CDK7 inhibitor, with an IC50 of 41 nM. Samuraciclib hydrochloride displays 45-, 15-, 230- and 30-fold selectivity over CDK1, CDK2 (IC50 of 578 nM), CDK5 and CDK9, respectively. Samuraciclib hydrochloride inhibits the growth of breast cancer cell lines with GI50 values between 0.2-0.3 μM. Samuraciclib hydrochloride has anti-tumor effects[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CT7001 hydrochloride; ICEC0942 hydrochloride. CAS No. 1805789-54-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103712A. | |
| Sancycline | Sancycline (6-Demethyl-6-deoxytetracycline) acts by reversibly binding to the 30 S ribosomal subunit and inhibiting protein translation by blocking entry of aminoacyl-tRNA into the ribosome a site similar to tetracycline (HY-A0107). Sancycline, four linearly fused six-membered rings with four stereocenters, is a rare semi-synthetic tetracycline (HY-A0107) prepared by hydrogenolysis of the chloro and benzylic hydroxy moieties of Declomycin [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Bonomycin; 6-Demethyl-6-deoxytetracycline. CAS No. 808-26-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17466. | |
| Sandaracopimaric acid | Sandaracopimaric acid is a diterpenoid with anti-inflammatory effect. Sandaracopimaric acid reduces the contraction of phenylephrine-induced pulmonary arteries with an EC 50 of 43.93 μM [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 471-74-9. Pack Sizes: 1 mg. Product ID: HY-133594. | |
| Sanfetrinem | Sanfetrinem (GV104326) is a β-lactamase-stable antibiotic. Sanfetrinem has broad-spectrum antimicrobial activity against both Gram-positive and Gram-negative bacteria [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GV104326. CAS No. 156769-21-0. Pack Sizes: 1 mg. Product ID: HY-106922. | |
| Sanfetrinem sodium | Sanfetrinem (GV104326) sodium is a beta-lactamase-stable antibiotic. Sanfetrinem sodium has broad-spectrum activity against gram-positive and gram-negative bacteria [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GV104326 sodium. CAS No. 141611-76-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106922A. | |
| Sanguinarine chloride | Sanguinarine (Sanguinarin) chloride, a benzophenanthridine alkaloid derived from the root of Sanguinaria Canadensis , can stimulate apoptosis via activating the production of reactive oxygen species (ROS). Sanguinarine-induced apoptosis is associated with the activation of JNK and NF-κB. Uses: Scientific research. Group: Natural products. Alternative Names: Sanguinarin chloride; Sanguinarium chloride; Pseudochelerythrine chloride. CAS No. 5578-73-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-N0052A. | |
| SANT-1 | SANT-1, a potent Smo antagonist, inhibits Hedgehog signaling. SANT-1 shows IC 50 s of 20 nM and 30 nM in Shh-LIGHT2 and SmoA1-LIGHT2 assay, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 304909-07-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-100224. | |
| Santacruzamate A | Santacruzamate A (CAY-10683, STA) is a potent and selective HDAC2 inhibitor with an IC50 of 119 pM. STA also exerts neuroprotective property against amyloid-? protein fragment 25-35. STA can be used for cancer and neurological disease research[1][2]. Uses: Scientific research. Group: Natural products. Alternative Names: CAY-10683. CAS No. 1477949-42-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-N0931. | |
| Santalol | Santalol is a mixture of α and β-isomer santalol. α-Santalol is found in sandalwood oil. α-Santalol is a promising anti-cancer agent against cancers such as oral, breast, prostate and skin cancer. Santalol has sedative activity [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 11031-45-1. Pack Sizes: 25 mg; 50 mg. Product ID: HY-N2059. | |
| Santin | Santin is a flavonol isolated from Dodonaea uscosa [1]. Uses: Scientific research. Group: Natural products. CAS No. 27782-63-4. Pack Sizes: 1 mg. Product ID: HY-N11423. | |
| Santonin | Santonin is an active principle of the plant Artemisia cina , which is formely used to treat worms [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Alpha-Santonin. CAS No. 481-06-1. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-B1761. | |
| Sapacitabine | Sapacitabine is an orally available nucleoside analog proagent that is structurally related to cytarabine. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CS682; CYC682. CAS No. 151823-14-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16445. | |
| Sapanisertib | Sapanisertib (INK-128; MLN0128; TAK-228) is an orally available, ATP-dependent mTOR1/2 inhibitor with an IC 50 of 1 nM for mTOR kinase. Uses: Scientific research. Group: Signaling pathways. Alternative Names: INK-128; MLN0128; TAK-228. CAS No. 1224844-38-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13328. | |
| Sapelizumab | Sapelizumab is a CHO-expressed humanized antibody targeting IL-6Ra/CD126. Sapelizumab has a huIgG2 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 145 kDa. The isotype control for Sapelizumab can refer to Human IgG2 kappa, Isotype Control (HY-P99002). Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 1535963-91-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990662. | |
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