MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Selepressin | Selepressin (FE 202158) is a selective vasopressin V 1A receptor agonist. Selepressin is a potent vasopressor. Selepressin can be used in the research of septic shock [1] [2] [4]. Uses: Scientific research. Group: Peptides. Alternative Names: FE 202158. CAS No. 876296-47-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-105239. |  |
| Seletracetam | Seletracetam (Ucb 44212), as an analog of the antiepileptic agent Levetiracetam, is a SV2A modulator for the research of epilepsy [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ucb 44212. CAS No. 357336-74-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-119810. | |
| Selexipag | Selexipag (NS-304) is an orally available and potent agonist for the Prostacyclin ( PGI 2 ) receptor (IP receptor). Uses: Scientific research. Group: Signaling pathways. Alternative Names: NS-304; ACT-293987. CAS No. 475086-01-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14870. | |
| Selfotel | Selfotel (CGS 19755) is a selective and competitive antagonist at N-methyl-D-aspartate (NMDA) -preferring receptor. CGS 19755 inhibits the binding of [3H]-3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid to NMDA-type receptors with an IC 50 of 50 nM [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CGS 19755. CAS No. 110347-85-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-15086. | |
| Selgantolimod | Selgantolimod (GS-9688) is an orally active, potent and selective toll-like receptor 8 (TLR8) agonist for the treatment of hepatitis B virus (HBV) and human immunodeficiency virus (HIV) infection[1][2][3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GS-9688. CAS No. 2004677-13-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-109137. | |
| Selicrelumab | Selicrelumab is an agonist CD40 antibody, induces changes in the tumor microenvironment. Selicrelumab can be used for the research of pancreatic cance and neoadjuvant study [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 1622140-49-1. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P99046. | |
| Seliforant | Seliforant (SENS-111) is a selective and orally histamine H4 receptor antagonist. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SENS-111. CAS No. 1164115-89-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109074. | |
| Selinexor | Selinexor (KPT-330), analog of KPT-185, is an orally bioavailable and selective CRM1 inhibitor [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KPT-330. CAS No. 1393477-72-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17536. | |
| Selisistat | Selisistat (EX-527) is a potent and selective SirT1 (Sir2 in Drosophila melanogaster) inhibitor with an IC 50 of 123 nM for SirT1. Selisistat alleviates pathology in multiple animal and cell models of Huntington's disease [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: EX-527. CAS No. 49843-98-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15452. | |
| Selitrectinib | Selitrectinib (LOXO-195) is a next-generation TRK kinase inhibitor, with IC 50 s of 0.6 nM and <2.5 nM for TRKA and TRKC , respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LOXO-195. CAS No. 2097002-61-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101977. | |
| Selnoflast | Selnoflast (RO7486967), formerly somalix/RG6418/IZD334, is an orally active, potent, selective and reversible small molecule NLRP3 inflammasome inhibitor. Selnoflast is a potent inhibitor of IL-1? release stimulated by NLRP3 activation in human Alzheimer's disease (AD) monocyte-derived macrophages. Selnoflast is promising for research of AD and systemic inflammatory diseases, such as ulcerative colitis and chronic obstructive pulmonary disease[1][2][3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Somalix; RO-7486967; IZD334. CAS No. 2260969-36-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-132831. | |
| Selonsertib | Selonsertib (GS-4997), an orally bioavailable, selective apoptosis signal-regulating kinase 1 ( ASK1 ) inhibitor with a pIC 50 of 8.3, has been evaluated as an experimental treatment for diabetic nephropathy and kidney fibrosis. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GS-4997. CAS No. 1448428-04-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-18938. | |
| Selpercatinib | Selpercatinib (LOXO-292) is a potent, selective RET kinase inhibitor with IC 50 values of 14.0 nM, 24.1 nM, and 530.7 nM for RET (WT), RET (V804M), and RET (G810R), respectively. Selpercatinib has anticancer activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LOXO-292. CAS No. 2152628-33-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114370. | |
| SelSA | SelSA is a selective, orally active inhibitor for histone deacetylase 6 ( HDAC6 ) with IC 50 of 56.9 nM. SelSA inhibits the phosphorylation of ERK1/2. SelSA inhibits the proliferation of breast cancer cells and hepatocellular carcinoma cells with IC 50 of 0.58-2.6 μM, inhibits cell migration and invasion of Huh7, and induces apoptosis. SelSA exhibits antitumor activity in mouse model [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1225038-92-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-162616. | |
| Seltorexant | Seltorexant (JNJ-42847922) is an orally active, high-affinity, and selective orexin-2 receptor (OX2R) antagonist ( pK i values of 8.0 and 8.1 for human and rat OX2R). Seltorexant (JNJ-42847922) crosses the blood-brain barrier and quickly occupies OX2R binding sites in the rat brain [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: JNJ-42847922. CAS No. 1293281-49-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109012. | |
| Seltorexant hydrochloride | Seltorexant hydrochloride (JNJ-42847922 hydrochloride) is an orally active, high-affinity, and selective OX2R antagonist ( pK i values of 8.0 and 8.1 for human and rat OX2R). Seltorexant hydrochloride crosses the blood-brain barrier and quickly occupies OX2R binding sites in the rat brain [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: JNJ-42847922 hydrochloride. CAS No. 1293284-49-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109012A. | |
| Selumetinib | Selumetinib (AZD6244) is selective, non-ATP-competitive oral MEK1/2 inhibitor, with an IC 50 of 14 nM for MEK1. Selumetinib (AZD6244) inhibits ERK1/2 phosphorylation. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AZD6244; ARRY-142886. CAS No. 606143-52-6. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-50706. | |
| Selumetinib sulfate | Selumetinib (AZD6244) is selective, non-ATP-competitive oral MEK1/2 inhibitor, with an IC 50 of 14 nM for MEK1. Selumetinib (AZD6244) inhibits ERK1/2 phosphorylation. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AZD6244 sulfate; ARRY-142886 sulfate. CAS No. 943332-08-9. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-50706A. | |
| Selurampanel | Selurampanel (BGG 492) is an orally active and competitive AMPA receptor antagonist with an IC 50 of 190 nM. Selurampanel has reasonable blood-brain barrier penetration. Selurampanel can be used for epilepsy research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BGG 492. CAS No. 912574-69-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-105860. | |
| Selvigaltin | Selvigaltin (GB1211) is an orally active galectin-3 small molecule inhibitor with an IC 50 value of 12 nM in rabbits, showing anti-tumor activity. Selvigaltin decreases galectin-3 levels in the liver and reduces biomarkers of liver function (AST, ALT, bilirubin), inflammation (cells foci) and fibrosis (PSR, SHG), as well as decreasing the mRNA and protein expression of several key inflammation and fibrosis biomarkers (IL6, TGFβ3, SNAI2, collagen). Selvigaltin restores T-cell activity and induces less tumors and metastasis [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GB1211. CAS No. 1978336-95-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-147041. | |
| Semagacestat | Semagacestat is a γ-secretase inhibitor, inhibits β-amyloid ( Aβ42 ), Aβ38 and Aβ40 with IC 50 s of 10.9, 12 and 12.1 nM, respectively; also inhibits Notch signaling with IC 50 of 14.1 nM. Semagacestat can be used for the research of alzheimer's disease [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LY450139. CAS No. 425386-60-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10009. | |
| Semaglutide | Semaglutide, a long-acting GLP-1 analogue, is a glucagon-like peptide-1 (GLP-1) receptor agonist. Semaglutide has the potential for type 2 diabetes treatment. Uses: Scientific research. Group: Peptides. CAS No. 910463-68-2. Pack Sizes: 500 μg; 1 mg; 5 mg; 10 mg. Product ID: HY-114118. | |
| Semaglutide acetate | Semaglutide acetate, a long-acting GLP-1 analogue, is a glucagon-like peptide-1 (GLP-1) receptor agonist. Semaglutide acetate has the potential for type 2 diabetes treatment. Uses: Scientific research. Group: Peptides. CAS No. 1997361-85-9. Pack Sizes: 500 μg; 1 mg; 5 mg; 10 mg. Product ID: HY-114118B. | |
| Semaglutide, FITC labeled | Semaglutide, FITC labeled is a long-acting, selective, competitive GLP-1R agonist that can penetrate the blood-brain barrier. After activating GLP-1R, Semaglutide, FITC labeled promotes insulin secretion, inhibits gastric emptying and appetite, and at the same time enhances autophagy, inhibits oxidative stress and apoptosis. Semaglutide, FITC labeled also regulates mitochondrial function and lipid metabolism (such as reducing de novo lipogenesis in the liver). Semaglutide, FITC labeled has activities such as lowering blood sugar, reducing weight, neuroprotection (such as improving motor function in Parkinson's disease models, reducing ?-synuclein aggregation) and improving hepatic steatosis. Semaglutide, FITC labeled can be used for the study of neurodegenerative diseases and liver diseases such as type 2 diabetes, obesity, Parkinson's disease, metabolic associated fatty liver disease (MASLD), and cancer[1][2][3][4][5]. Uses: Scientific research. Group: Peptides. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114118F. | |
| Semaglutide TFA | Semaglutide TFA is a long-acting, selective, competitive GLP-1R agonist that can penetrate the blood-brain barrier. After activating GLP-1R, Semaglutide TFA promotes insulin secretion, inhibits gastric emptying and appetite, and at the same time enhances autophagy, inhibits oxidative stress and apoptosis. Semaglutide TFA also regulates mitochondrial function and lipid metabolism (such as reducing de novo lipogenesis in the liver). Semaglutide TFA has activities such as lowering blood sugar, reducing weight, neuroprotection (such as improving motor function in Parkinson's disease models, reducing ?-synuclein aggregation) and improving hepatic steatosis. Semaglutide TFA can be used for the study of neurodegenerative diseases and liver diseases such as type 2 diabetes, obesity, Parkinson's disease, metabolic associated fatty liver disease (MASLD), and cancer[1][2][3][4][5]. Uses: Scientific research. Group: Peptides. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-114118A. | |
| Semax acetate | Semax acetate is a nootropic neuroprotective peptide. Semax acetate can be used in the research of brain stroke [1]. Uses: Scientific research. Group: Peptides. CAS No. 2828433-33-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P1146A. | |
| Semaxinib | Semaxinib (SU5416) is a potent and selective inhibitor of VEGFR (Flk-1/KDR) with an IC50 of 1.23 ?M[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SU5416. CAS No. 204005-46-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-10374. | |
| SEMBL | SEMBL is a potent NF-κB inhibitor. SEMBL can inhibit NF-κB-DNA binding, and also inhibits NF-κB-dependent inflammatory cytokine secretions. SEMBL inhibits cancer cell migration and invasion via decreasing MMP expression. SEMBL can be used for researching anticancer [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1443448-82-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-124651. | |
| Se-Methylselenocysteine | Se-Methylselenocysteine, a precursor of Methylselenol, has potent cancer chemopreventive activity and anti-oxidant activity. Se-Methylselenocysteine is orally bioavailable, and induces apoptosis [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Methylselenocysteine; Se-Methylseleno-L-cysteine. CAS No. 26046-90-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114245. | |
| Semicarbazide hydrochloride | Semicarbazide hydrochloride is an orally active urea derivative. Semicarbazide hydrochloride binds to copper or iron in cells. Semicarbazide hydrochloride inhibits the activity of soluble semicarbazide sensitive amine oxidase ( SSAO ). Semicarbazide hydrochloride damages cartilage, blood vessels, ovaries, testicles, and thyroid follicles [1] [2] [3] [4] [5] [6] [7] [8] [9]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Aminourea hydrochloride; Hydrazinecarboxamide hydrochloride. CAS No. 563-41-7. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-Y0470. | |
| Semorinemab | Semorinemab (RG 6100) is an anti- Tau humanized IgG4 monoclonal antibody, targets the N-terminal portion of the Tau protein (amino acid residues 6-23). Semorinemab binds with human Tau with a K d value of 3.8 nM. Semorinemab can be used for the research of Alzheimer's Disease [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: RG 6100; RO7105705; MTAU-9937A. CAS No. 2159141-27-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99399. | |
| Semustine | Semustine is a DNA alkylator , binds to DNA, and acts as a cancer chemotherapeutic agent [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 13909-09-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13747. | |
| Senaparib | Senaparib (IMP4297) is a highly potent, selective and orally active PARP1/2 inhibitor. Senaparib (IMP4297) exhibits strong antitumor activity in animal models [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: IMP4297; JS109. CAS No. 1401682-78-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-137450. | |
| Senecionine | Senecionine (Senecionan-11,16-dione, 12-hydroxy-) is a pyrrolizidine alkaloid could be isolated from Senecio vulgaris. Senecionine decreases the activities of glutathione S-transferase, aminopyrine demethylase and arylhydrocarbon hydroxylase (AHH) [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Senecionan-11,16-dione, 12-hydroxy-; Aureine; Senecionin. CAS No. 130-01-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N2560. | |
| Senexin A | Senexin A is an inhibitor of CDK8/19 (IC50: 280 nM, CDK8) and an inhibitor downstream of p21 transcription. It only inhibits p21-induced transcription but does not inhibit other biological effects of p21. Senexin A inhibits CMV-GFP induction as well as the p21 stimulatory activity of the consensus NF-?B-dependent promoters[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1366002-50-7. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15681. | |
| Senexin B | Senexin B (SNX2-1-165; BCD-115) is a potent, highly water-soluble and bioavailable CDK8/19 inhibitor, with Kds of 140 nM for CDK8 and 80 nM for CDK19. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SNX2-1-165; BCD-115. CAS No. 1449228-40-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101800. | |
| Senicapoc | Senicapoc (ICA-17043) is a potent and selective Gardos channel (Ca 2+ -activated K + channel; KCa3.1 ) blocker with an IC 50 of 11 nM. Senicapoc blocks Ca 2+ -induced rubidium flux from human RBCs with an IC 50 value of 11 nM and inhibits RBC dehydration with IC 50 of 30 nM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ICA-17043. CAS No. 289656-45-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-50694. | |
| Seniprutug | Seniprutug is an anti- TRBV9 human IgG1 κ monoclonal antibody [1]. Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001). Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 2484772-72-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990762. | |
| Senktide | Senktide is a potent, selective agonist of the neuromedin K3 (NK3) receptor (EC50=0.5-3 nM). Senktide less potently agonizes the NK1 receptor (EC50=35 μM). Senktide is promising for research of neurological disease[1][2][3][4][5]. Uses: Scientific research. Group: Peptides. CAS No. 106128-89-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P0187. | |
| Sennoside A | Sennoside A is an anthraquinone glycoside found in senna ( Cassia angustifolia ). Sennoside A is an HIV-1 inhibitor (IC 50 =3.8 μM) that inhibits HIV-1 replication. Sennoside A also inhibits HIV-1 reverse transcriptase (RT)-related DNA polymerase (RDDP) and ribonuclease H (Ribonuclease H) with IC 50 s of 1.9 μM and 5.3 μM, respectively [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. CAS No. 81-27-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-N0365. | |
| Sennoside B | Sennoside B is a potent and orally active platelet-derived growth factor (PDGF) inhibitor. Sennoside B inhibits cell proliferation and the expression of phosphorylation of PDGFR-β, STAT-5, AKT and ERK induced by PDGF-BB. Sennoside B shows gastroprotective activities. Sennoside B has the potential for the research of gastritis [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 128-57-4. Pack Sizes: 10 mg; 25 mg; 50 mg. Product ID: HY-N0366. | |
| SENP1-IN-3 | SENP1-IN-3 is a specific deSUMOylation protease 1 (SENP1) inhibitor extracted from patent CN110627860, Compound 17. SENP1-IN-3 is developed for tumor radiosensitivity enhancement[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2416910-59-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-134596. | |
| SEP-363856 hydrochloride | SEP-363856 (SEP-856) hydrochloride, an orally active TAAR1 and 5-HT1A agonist and CNS active psychotropic agent with a unique, non-D2/5-HT2A mechanism of action, exerts its antipsychotic-like effects. SEP-363856 hydrochloride has the potential for the study of schizophrenia [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SEP-856 hydrochloride. CAS No. 1310422-41-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-136109. | |
| Sepantronium bromide | Sepantronium bromide (YM-155) is a survivin inhibitor with an IC 50 of 0.54 nM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: YM-155. CAS No. 781661-94-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10194. | |
| (-)-(S)-Equol | (-)-(S)-Equol is a high affinity ligand for estrogen receptor β with a K i of 0.73 nM. Uses: Scientific research. Group: Natural products. CAS No. 531-95-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100583. | |
| Serabelisib | Serabelisib (MLN1117) is a selective p110α inhibitor with an IC 50 of 15 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MLN1117; INK1117; TAK-117. CAS No. 1268454-23-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12285. | |
| Seralutinib | Seralutinib (GB002) is an inhaled PDGFRα and PDGFRβ inhibitor. Seralutinib also targets to CSF1R and c-KIT with IC 50 s of 8 nM and 14 nM, respectively. Seralutinib (GB002) is used in the study for pulmonary arterial hypertension [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GB002; PK10571. CAS No. 1619931-27-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109190. | |
| Seratrodast | Seratrodast (AA 2414), an orally active antiasthmatic agent, is a thromboxane A2 receptor (TP) antagonist and ferroptosis inhibitor. Seratrodast reduces lipid ROS production, modulates the systemic xc-/GSH/GPX4 axis, and inhibits JNK phosphorylation and p53 expression. Seratrodast exhibits anti-asthmatic and anti-epileptic activity [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AA 2414. CAS No. 112665-43-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0774. | |
| Serdemetan | Serdemetan (JNJ-26854165) is a potent anticancer agent with radiosensitizing activity. Serdemetan exhibits antiproliferative activity in various p53 wild-type tumor cells. Serdemetan also antagonizes the Mdm2-HIF1? axis leading to decreased levels of glycolytic enzymes[1][2][3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: JNJ-26854165. CAS No. 881202-45-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12025. | |
| Sergliflozin etabonate | Sergliflozin etabonate (GW-869682X) is a potent and orally active sodium glucose cotransporter (SGLT2) inhibitor. Sergliflozin etabonate shows antidiabetic and antihyperglycemic effects. Sergliflozin etabonate significantly reduces non-fasting blood glucose levels in diabetic mice. Sergliflozin etabonate has the potential for the research of diabetes [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GW-869682X. CAS No. 408504-26-7. Pack Sizes: 10 mM * 1 mL; 1 mg. Product ID: HY-12611. | |
| Seribantumab | Seribantumab (MM 121) is a fully human IgG2 monoclonal antibody that targets HER3. Seribantumab blocks the activation of epidermal growth factor receptor (ErbB) family members and its downstream signal. Seribantumab inhibits neuregulin 1 (NRG1) fusion-dependent tumorigenesis in vitro and in vivo in breast, lung and ovarian patient-derived cancer models [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: SAR 256212; MM 121; Anti-Human ERBB3/ErbB 3 Recombinant Antibody. CAS No. 1334296-12-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99268. | |
| Serotonin | Serotonin is a monoamine neurotransmitter in the CNS and an endogenous 5-HT receptor agonist. Serotonin is also a catechol O-methyltransferase ( COMT ) inhibitor with a K i of 44 μM. Uses: Scientific research. Group: Natural products. Alternative Names: 5-Hydroxytryptamine; 5-HT. CAS No. 50-67-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1473A. | |
| Serotonin-d4 | Serotonin-d4 is deuterium labeled Serotonin. Serotonin is a monoamine neurotransmitter in the CNS and an endogenous 5-HT receptor agonist. Serotonin is also a catechol O-methyltransferase (COMT) inhibitor with a Ki of 44 ?M. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: 5-Hydroxytryptamine-d4; 5-HT-d4. CAS No. 58264-95-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-B1473AS. | |
| Serotonin hydrochloride | Serotonin (5-Hydroxytryptamine) hydrochloride is a monoamine neurotransmitter in the CNS and an endogenous 5-HT receptor agonist. Serotonin hydrochloride is also a catechol O-methyltransferase ( COMT ) inhibitor with a K i of 44 μM. Uses: Scientific research. Group: Natural products. Alternative Names: 5-Hydroxytryptamine hydrochloride; 5-HT hydrochloride. CAS No. 153-98-0. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 250 mg. Product ID: HY-B1473. | |
| Serplulimab | Serplulimab (HLX 10) is humanized monoclonal anti- PD-1 antibody. Serplulimab can be used in research of small cell lung cancer [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: HLX 10. CAS No. 2231029-82-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99118. | |
| Sertaconazole nitrate | Sertaconazole nitrate (FI7056) is a broad-spectrum topical antifungal agent, exhibits anti-inflammatory activity via activation of a p38-COX-2-PGE2 pathway. Sertaconazole nitrate is also a microtubule inhibitor, shows antiproliferative effect, induces apoptosis and autophagy , and can also inhibit the migration of cells [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FI7056. CAS No. 99592-39-9. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0736A. | |
| Sertindole | Sertindole (Lu 23-174) is an orally active 5-HT 2A , 5-HT 2C , dopamine D 2 , and αl-adrenergic receptors antagonist. Sertindole shows antipsychotic activity and anti-proliferative activity to multiple cancer cells [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Lu 23-174. CAS No. 106516-24-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-14543. | |
| Sertraline hydrochloride | Sertraline hydrochloride is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. Sertraline hydrochloride is researched for a number of diseases, such as major depressive disorder and obsessive [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 79559-97-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-B0176A. | |
| Serum thymic factor acetate | Serum thymic factor acetate (Thymulin acetate) is the acetate salt form of Serum thymic factor (HY-P3206). Serum thymic factor acetate is a zinc-dependent immunomodulatory peptide hormone, which can be produced by the thymic epithelial cells. Serum thymic factor acetate stimulates the release of hormones from the pituitary gland, exhibits hypophysiotropic activity. Serum thymic factor acetate protects rats from Cephaloridine (HY-B2072)-induced nephrotoxicity by inhibiting ERK activation. Serum thymic factor acetate exhibits anti-diabetic, anti-inflammatory and analgesic effects. Serum thymic factor acetate can be used in research about endocrine, reproductive, neurodegenerative and inflammatory diseases [1] [2] [3] [4]. Uses: Scientific research. Group: Peptides. Alternative Names: Thymulin acetate; Thymic factor acetate. CAS No. 125117-65-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P3206A. | |
| Sesame Oil | Sesame Oil is a vegetable oil. Sesame Oil can be extracted from the seeds of Sesamum indicum L. Sesame Oil decreases NF-?B, aspartate aminotransferase, alanine aminotransferase, IL-1?, IL-4 and nitric oxide. Sesame Oil has antitumor activity against malignant melanoma. Sesame Oil has protective effects against liver damage caused by various agents such as Cisplatin (HY-17394) and Acetaminophen (HY-66005). Sesame Oil shows antinociceptive and anti-inflammatory activities[1][2][3][4][5][6][7][8]. Uses: Scientific research. Group: Signaling pathways. CAS No. 8008-74-0. Pack Sizes: 50 mL; 100 mL. Product ID: HY-154629. | |
| Sesamin | Sesamin, abundant lignan found in sesame oil, is a potent and selective delta 5 desaturase inhibitor in polyunsaturated fatty acid biosynthesis. Sesamin exerts effective neuroprotection against cerbral ischemia [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 607-80-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-N0121. | |
| (-)-Sesamin | (-)-Sesamin isolated from Asarum forbesii Maxim, is an isomer of Sesamin. Sesamin is a potent and selective delta 5 desaturase inhibitor in polyunsaturated fatty acid biosynthesis [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 13079-95-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-N0121A. | |
| Sesamol | Sesamol is a constituent of sesame oil. Sesamol shows a free radical scavenging activity. Sesamol shows an IC 50 =5.95±0.56 μg/mL in the DPPH assay. Anti-oxidant activities [1]. Anticancer activities [2]. Uses: Scientific research. Group: Natural products. CAS No. 533-31-3. Pack Sizes: 10 mM * 1 mL; 10 g; 25 g. Product ID: HY-N1417. | |
| Sesamolin | Sesamolin, isolated from Sesamum indicum , has antioxidative activity, Sesamolin inhibits lipid peroxidation and shows neuroprotection effect. Sesamolinl potently inhibits MAPK cascades by preventing phosphorylation of JNK , p38 MAPKs , and caspase-3 but not ERK-MAPK expression [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. CAS No. 526-07-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-N0809. | |
| SET2 | SET2 is a selective TRPV2 antagonist ( IC 50 =0.46 μM). SET2 blocks the TRP channel and suppresses prostate cancer cells migration. SET2 reduces the lysophosphatidic acid (LPA, a TRPV2 activator)-induced cytoplasmic calcium increases [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2313525-20-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132222. | |
| Setanaxib | Setanaxib (GKT137831) is a selective NADPH oxidase ( NOX1/4 ) inhibitor with K i s of 140 and 110 nM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GKT137831; GKT831. CAS No. 1218942-37-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12298. | |
| SETDB1-TTD-IN-1 | SETDB1-TTD-IN-1 is a potent, selective and endogenous binder competitive ligand of SET domain bifurcated protein 1 tandem tudor domain (SETDB1-TTD) that binds to TTD, with a Kd of 88 nM. SETDB1-TTD-IN-1 increases SETDB1 methyltransferase activity. SETDB1-TTD-IN-1 can be used for the research of biological functions and disease associations of SETDB1-TTD[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2755823-12-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-141539. | |
| Sethoxydim | Sethoxydim is a postemergent herbicide. Sethoxydim inhibits plant acetyl-coenzyme A carboxylase ( ACCase ) activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAS 9052. CAS No. 74051-80-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-135753. | |
| (S)-Ethyl 2-amino-4-fluoro-4-methylpentanoate sulfate | (S)-Ethyl 2-amino-4-fluoro-4-methylpentanoate sulfate is a leucine derivative [1]. Uses: Scientific research. Group: Peptides. CAS No. 848949-85-9. Pack Sizes: 100 mg; 250 mg; 500 mg. Product ID: HY-77026. | |
| Setidegrasib | Setidegrasib (KRAS G12D inhibitor 17, Example 8) is a PROTAC KRAS degrader (DC50: 37 nM). Setidegrasib induces the degradation of G12D-mutation KRAS protein. Setidegrasib has antitumor effect. (Blue: E3 ligase ligand (HY-168699); Black: linker (HY-168698); Pink: G12D ligand (HY-168700))[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KRAS G12D inhibitor 17. CAS No. 2821793-99-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-148273. | |
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