MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| SLLK, Control Peptide for TSP1 Inhibitor(TFA) | SLLK, Control Peptide for TSP1 Inhibitor (TFA) is a control peptide for LSKL, which is a Thrombospondin (TSP-1) inhibitor. Uses: Scientific research. Group: Peptides. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P0301A. |  |
| SLM6031434 hydrochloride | SLM6031434 hydrochloride is a highly selective sphingosine kinase 2 (SphK2) inhibitor with K i s of 0.4 μM, 0.5 μM, >20 μM, 22 μM for mSphK2, rSphK2, mSphK1 and rSphK1, respectively. SLM6031434 hydrochloride decrease Sphingosine 1-phosphate (S1P) levels in U937 monocytic leukemia cells. SLM6031434 hydrochloride has the potential for renal fibrosis research [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1897379-34-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-120268A. | |
| SLP7111228 hydrochloride | SLP7111228 (hydrochloride) is a biochemical reagent. Uses: Scientific research. Group: Signaling pathways. CAS No. 1449768-48-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-120152A. | |
| SLU-PP-332 | SLU-PP-332 is a pan- Estrogen Receptor/ERR agonist with EC 50 values of 98, 230 and 430 nM for ERRα , ERRβ and ERRγ , respectively. SLUPP-332 enhances mitochondrial function and cellular respiration in skeletal muscle cell lines. SLU-PP-332 has the potential to study metabolic diseases as well as improve muscle function [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 303760-60-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-155673. | |
| (S)-LY-3381916 | (S)-LY-3381916 ((S)-IDO1-IN-5; Example 1B) is an active S-isomer of LY-3381916. (S)-LY-3381916 binds to IDOL with an IC 50 value less than 1.5 μΜ [1]. LY-3381916 is a potent, selective and brain penetrated inhibitor of Indoleamine 2,3-Dioxygenase 1 (IDO1) activity, binds to apo-IDO1 lacking heme rather than mature heme-bound IDO1 [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (S)-IDO1-IN-5. CAS No. 2166616-76-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111540B. | |
| SM-102 | SM-102 is an amino cationic lipid useful in the formation of lipid nanoparticles ( LNPs ). SM-102 has higher transfection efficiency. SM-102 plays an important role in the effectiveness of lipid nanoparticles (LNPs) in delivering mRNA therapeutics and vaccines [1] [2]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 2089251-47-6. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-134541. | |
| SM-164 | SM-164 is a cell-permeable Smac mimetic compound. SM-164 binds to XIAP protein containing both the BIR2 and BIR3 domains with an IC 50 value of 1.39 nM and functions as an extremely potent antagonist of XIAP. Uses: Scientific research. Group: Signaling pathways. CAS No. 957135-43-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15989. | |
| SM-164 hydrochloride | SM-164 hydrochloride is a cell-permeable Smac mimetic compound. SM-164 binds to XIAP protein containing both the BIR2 and BIR3 domains with an IC 50 value of 1.39 nM and functions as an extremely potent antagonist of XIAP. Uses: Scientific research. Group: Signaling pathways. CAS No. 2734174-02-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15989A. | |
| SM1-71 | SM1-71 (compound 5) is a potent TAK1 inhibitor, with a Ki of 160 nM, it also can covalently inhibit MKNK2, MAP2K1/2/3/4/6/7, GAK, AAK1, BMP2K, MAP3K7, MAPKAPK5, GSK3A/B, MAPK1/3, SRC, YES1, FGFR1, ZAK (MLTK), MAP3K1, LIMK1 and RSK2. SM1-71 can inhibit proliferation of multiple cancer cell lines[1][2][3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2088179-99-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136848. | |
| Sm4 | Sm4 is a SOX18 inhibitor. Sm4 shows SOX18-DNA binding inhibitory activity. Sm4 selectively affects SOX18 transcriptional output in vitro. Sm4 blocks SoxF transcriptional activity in vivo. Sm4 can be used for cancer metastasis and vascular cancers research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 365542-77-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116940. | |
| SM-433 | SM-433, a Smac mimetic, function as inhibitor of inhibitor of apoptosis proteins (IAPs). SM-433 exhibits strong binding affinity XIAP BIR3 protein with an IC 50 <1 μM (patent WO2008128171A2) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1071992-81-8. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-138059. | |
| (S)-Malic acid (Standard) | (S)-Malic acid (Standard) is the analytical standard of (S)-Malic acid. This product is intended for research and analytical applications. (S)-Malic acid ((S)-2-Hydroxysuccinic acid) is a dicarboxylic acid in naturally occurring form, contributes to the pleasantly sour taste of fruits and is used as a food additive. In Vitro: It is showed that ME is essential for (S)-2-Hydroxysuccinic acid (L-malic acid) utilization in L. casei. Furthermore, deletion of either the gene encoding the histidine kinase or the response regulator of the TC system resulted in the loss of the ability to grow on (S)-2-Hydroxysuccinic acid, thus indicating that the cognate TC system regulates and is essential for the expression of ME. Transcriptional analyses shows that expression of maeE is induced in the presence of (S)-2-Hydroxysuccinic acid and repressed by glucose, whereas TC system expression is induced by (S)-2-Hydroxysuccinic acid and is not repressed by glucose [1]. Uses: Scientific research. Group: Natural products. CAS No. 97-67-6. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-Y1069R. | |
| (S)-Mandelic acid | (S)-Mandelic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 17199-29-0. Pack Sizes: 100 g. Product ID: HY-Y0816. | |
| SMANT hydrochloride | SMANT hydrochloride is a Smoothened ( Smo ) signaling inhibitor. SMANT hydrochloride is antagonist of Smo accumulation within the primary cilium (PC). SMANT hydrochloride has an equivalent activity in inhibiting SmoM2 (oncogenic form of Smo) and wild-type Smo [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1177600-74-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108508. | |
| SMAP-2 | SMAP-2 (DT-1154) is an orally active protein phosphatase 2A (PP2A) activator, with anti-cancer activity[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DT-1154. CAS No. 1809068-70-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-120272. | |
| SMARCA2/4-IN-2 | SMARCA2/4-IN-2 is a PROTAC target protein ligand ( Ligands for Target Protein for PROTACs ). SMARCA2/4-IN-2 can be used for synthesis PROTAC SMARCA2/4-degrader-5 (HY-159456) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1339378-93-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-163926. | |
| SMCC | SMCC is a protein crosslinker. SMCC-conjugated antigen coupled spleen cells to induce antigen-specific immune responses [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 64987-85-5. Pack Sizes: 100 mg; 250 mg; 500 mg; 1 g; 5 g; 25 g; 100 g. Product ID: HY-42360. | |
| SMCC-DM1 | SMCC-DM1 (DM1-SMCC) is a agent-linker conjugate composed of a potent microtubule-disrupting agent DM1 and a linker SMCC to make antibody agent conjugate (ADC)[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DM1-SMCC. CAS No. 1228105-51-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101070. | |
| SMD-3040 | SMD-3040 is a potent and selective SMARCA2 PROTAC degrader (DC50: 12 nM; Dmax: 91%). SMD-3040 can inhibit tumor cell proliferation and exhibits antitumor activity. SMD-3040 can be used in the study of tumors such as melanoma[1]. (SMARCA2/4-ligand (HY-171765); HY-112078 VHL ligand (HY-112078)). Uses: Scientific research. Group: Signaling pathways. CAS No. 3033109-92-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-156568. | |
| S-Me-DM4 | S-Me-DM4 is a metabolite of DM4 S-methylated by intracellular enzyme. DM4 (HY-100503) is a microtubule-depolymerizing maytansinoid with strong cytotoxicity. DM4 can be used as an ADC Cytotoxin molecule[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 890654-03-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-148818. | |
| (S)-Mephenytoin | (S)-Mephenytoin ((+)-Mephenytoin) is an anticonvulsive agent. (S)-Mephenytoin is a substrate of the cytochrome P450 (CYP) isoform CYP2C19. (S)-Mephenytoin can be used for the analysis of cytochrome P450 metabolism [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (+)-Mephenytoin. CAS No. 70989-04-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1184A. | |
| (S)-Mephenytoin (Standard) | (S)-Mephenytoin (Standard) is the analytical standard of (S)-Mephenytoin. This product is intended for research and analytical applications. (S)-Mephenytoin ((+)-Mephenytoin) is an anticonvulsive agent. (S)-Mephenytoin is a substrate of the cytochrome P450 (CYP) isoform CYP2C19. (S)-Mephenytoin can be used for the analysis of cytochrome P450 metabolism[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (+)-Mephenytoin (Standard). CAS No. 70989-04-7. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1184AR. | |
| SMER28 | SMER28 is a positive regulator of autophagy acting via an mTOR-independent mechanism. SMER28 prevents the accumulation of amyloid beta peptide. Uses: Scientific research. Group: Signaling pathways. CAS No. 307538-42-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-100200. | |
| S-Methoprene | S-Methoprene is an insect juvenile hormone analog and effective insecticide that blocks the transition from pupa to adult. S-Methoprene is also a CB(1) receptor ligand and inhibits the binding of the CB1 receptor antagonist [ 3 H]CP-55940 to the CB1 receptor ( IC 50 : 19.31 μM) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (+)-Methoprene; (7S)-Methoprene. CAS No. 65733-16-6. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B1161A. | |
| (S)-methyl 2-amino-3-cyclohexylpropanoate hydrochloride | (S)-methyl 2-amino-3-cyclohexylpropanoate hydrochloride is an alanine derivative [1]. Uses: Scientific research. Group: Peptides. CAS No. 17193-39-4. Pack Sizes: 10 g; 25 g. Product ID: HY-W007136. | |
| (S)-Methyl 2-oxooxazolidine-4-carboxylate | 4-Oxazolidinecarboxylic acid, 2-oxo-, methyl ester, (S)- is a biological molecule. Uses: Scientific research. Group: Signaling pathways. CAS No. 132682-22-5. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-Z0425. | |
| (S)-Methyl 3-amino-2-((tert-butoxycarbonyl)amino)propanoate hydrochloride | (S)-Methyl 3-amino-2-((tert-butoxycarbonyl)amino)propanoate hydrochloride is an alanine derivative [1]. Uses: Scientific research. Group: Peptides. CAS No. 181228-33-1. Pack Sizes: 250 mg; 1 g; 5 g. Product ID: HY-W006152. | |
| S-Methylglutathione | S-Methylglutathione is an S-substitued glutathione and a stronger nucleophile than GSH [1]. S-Methylglutathione has inhibitory effect on glyoxalase 1 [2]. Uses: Scientific research. Group: Peptides. CAS No. 2922-56-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-W009177. | |
| S-Methylisothiourea sulfate | S-Methylisothiourea sulfate is a potent, selective and competitive inhibitor of inducible nitric oxide synthase (iNOS). S-Methylisothiourea sulfate exerts beneficial effects in rodent models of septic shock [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 867-44-7. Pack Sizes: 10 mM * 1 mL; 25 mg. Product ID: HY-79457. | |
| S-Methyl-L-cysteine | S-Methyl-L-cysteine is a natural product that acts as a substrate in the catalytic antioxidant system mediated by methionine sulfoxide reductase A (MSRA), with antioxidative, neuroprotective, and anti-obesity activities. Uses: Scientific research. Group: Natural products. Alternative Names: L-S-Methylcysteine. CAS No. 1187-84-4. Pack Sizes: 10 mM * 1 mL; 1 g. Product ID: HY-B2188. | |
| (S)-Metolachor | (S)-Metolachor, a derivative of aniline, is a major pesticide in use. Uses: Scientific research. Group: Signaling pathways. CAS No. 87392-12-9. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg. Product ID: HY-117279. | |
| SMI-4a | SMI-4a (TCS-PIM-1-4a) is a poten, selective, cell-permeable and ATP-competitive Pim-1 inhibitor with an IC50 of 24 ?M and a Ki of 0.6 ?M. SMI-4a also inhibits Pim-2 (IC50 of 100 ?M), and does not significantly inhibit the other serine/threonine- or tyrosine-kinases. SMI-4a has anticancer activity[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TCS-PIM-1-4a. CAS No. 438190-29-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16576A. | |
| SMIFH2 | SMIFH2 is a formin specific inhibitor. SMIFH2 inhibits actin polymerization by Formins and affects the actin cytoskeleton[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 340316-62-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16931. | |
| Smilagenin | Smilagenin (SMI) is a small-molecule steroidal sapogenin from Anemarrhena asphodeloides and Pelargonium hortorum widely used in traditional Chinese medicine for treating chronic neurodegeneration diseases [1]. Smilagenin (SMI) improves memory of aged rats by increasing the muscarinic receptor subtype 1 (M1)-receptor density [2]. Smilagenin (SMI) attenuates Aβ(25-35)-induced neurodegenerationvia stimulating the gene expression of brain-derived neurotrophic factor, may represents a novel therapeutic strategy for AD [3]. Uses: Scientific research. Group: Natural products. CAS No. 126-18-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106353. | |
| Smilagenin acetate | Smilagenin acetate is a sapogenin derivative extracted from patent US20030004147A1. Smilagenin acetate increases the expression of acetylcholine m2 receptors and can be used for the research of dementia [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 4947-75-5. Pack Sizes: 5 mg. Product ID: HY-N7421. | |
| (S)-Mirtazapine | (S)-Mirtazapine ((S)-Org3770) is a S(+)-enantiomer of Mirtazapine with pronociceptive properties in an animal model of acute thermal nociception. (S)-Mirtazapine is a stereoselective 5-HT 2 receptor antagonist. (S)-Mirtazapine is metabolized by CYP2D6 and CYP1A2 [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (S)-Org3770; (S)-6-Azamianserin. CAS No. 61337-87-9. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-B0352A. | |
| SMN-C3 | SMN-C3 is an orally active SMN2 splicing modulator and has the potential to treat spinal muscular atrophy (SMA). Uses: Scientific research. Group: Signaling pathways. CAS No. 1449597-34-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-112633. | |
| SMO-IN-2 | SMO-IN-2 (compound 1) is a potent smoothened (SMO) inhibitor with an IC 50 value of 123.4 nM for hedgehog (Hh) signaling pathway. SMO-IN-2 has antiproliferative activity against human medulloblastoma cell line Daoy. Anticancer activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1822355-27-0. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-150564. | |
| SMPT | SMPT is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 112241-19-7. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-126405. | |
| SMS121 | SMS121 is a CD36 inhibitor with a KD values of about 5 μM. SMS121 reduces the uptake of lipids and inhibits cell viability in acute myeloid leukemia cells. SMS121 has antitumor activity[1]. Uses: Scientific research. Group: Signaling pathways. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-163541. | |
| SMS2-IN-1 | SMS2-IN-1 is a potent and highly selective sphingomyelin synthase 2 (SMS2) inhibitor with an IC50 of 6.5 nM and a Kd of 37 nM. SMS2-IN-1 shows 150-fold selectivity for SMS2 over SMS1 (IC50 of 1000 nM)[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2098890-15-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-102041. | |
| SN-008 | SN-008, a less active SN-011 analog, can be used as a negative control [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2249106-01-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145009. | |
| SN-011 | SN-011 is a potent and selective mouse and human STING inhibitor, with an IC 50 of 76 nM for STING signaling. SN-011 competes with cyclic dinucleotide (CDN) for the binding pocket of the STING dimer, blocking CDN binding and STING activation. SN-011 can be used for the research of STING-driven autoimmune and inflammatory disease [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2249435-90-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145010. | |
| SN 2 | SN 2 is a potent activator of TRPML3 ion channel with an EC 50 of 1.8 μM [1]. SN 2 also acts as a potent inhibitor of Dengue virus 2 (DENV2) and Zika virus (ZIKV) [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 823218-99-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-16696. | |
| SN-38 | SN-38 is an active metabolite of the Topoisomerase I inhibitor Irinotecan. SN-38 inhibits DNA and RNA synthesis with IC 50 s of 0.077 and 1.3 μM, respectively. SN-38 is a payload of sacituzumab govitecan (HY -132254) [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. Alternative Names: 7-Ethyl-10-hydroxycamptothecin. CAS No. 86639-52-3. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-13704. | |
| SN-38-d3 | SN-38-d3 is the deuterium labeled SN-38. SN-38 (NK012) is an active metabolite of the Topoisomerase I inhibitor Irinotecan. SN-38 (NK012) inhibits DNA and RNA synthesis with IC50s of 0.077 and 1.3 ?M, respectively[1][2][3][4]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: NK012-d3. CAS No. 718612-49-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-13704S. | |
| SN-38 glucuronide | SN-38 glucuronide is an inactive metabolite of the anticancer active molecule Irinotecan (HY-16562) and has toxic effects on the gastrointestinal tract. Irinotecan is a topoisomerase I inhibitor which can be used for researching colon and rectal cancer [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SN-38G. CAS No. 121080-63-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-126373. | |
| SN40 | SN40 is a potent amino acid transport (AAT) inhibitor with K i s of 7.29 μM, 2.42 μM, 2.94 μM, 5.55 μM, 24.43 μM and 5.55 μM for rat ASCT2, human ASCT2, EAAT1, EAAT2, EAAC1 and EAAT5, respectively. SN40 can be used for researching anticancer [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2768663-14-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-146241. | |
| SN40 hydrochloride | SN40 hydrochloride is a potent amino acid transport (AAT) inhibitor with K i s of 7.29 μM, 2.42 μM, 2.94 μM, 5.55 μM, 24.43 μM and 5.55 μM for rat ASCT2, human ASCT2, EAAT1, EAAT2, EAAC1 and EAAT5, respectively. SN40 hydrochloride can be used for researching anticancer [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2768663-15-4. Pack Sizes: 1 mg; 5 mg. Product ID: HY-146241B. | |
| SN50 | SN50 is a cell permeable inhibitor of NF-?B translocation. Uses: Scientific research. Group: Peptides. CAS No. 213546-53-3. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P0151. | |
| SN52 | SN52 is a potent, competitive, and cell-permeable inhibitor of NF-?B2. SN52 is a variant of the SN50 peptide and inhibits the nuclear translocation of p52-RelB heterodimers. SN52 has a strong radiosensitization effect on prostate cancer cells. SN52 can be used for cancer research[1]. Uses: Scientific research. Group: Peptides. CAS No. 1071173-56-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P3229. | |
| Snailase, Snail gastrointestinal | Snailase, Snail gastrointestinal is an enzyme mixture composed of more than 20 enzymes, which is often used for enzymatic hydrolysis of purified flavonoid glycosides. Snailase can be obtained from the digestive tract and includes cellulase, sucrase, hemicellulase, pectinase, polygalacturonase, protease, etc[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 158736-45-9. Pack Sizes: 5 g. Product ID: HY-E70130. | |
| SNAP 94847 hydrochloride | SNAP 94847 hydrochloride is a novel, high affinity selective melanin-concentrating hormonereceptor1 (MCHR1) antagonist with ( K i=2.2 nM, K d=530 pM), it displays >80-fold and >500-fold selectivity over MCHα1A and MCHD2 receptors respectively. SNAP 94847 hydrochloride binds with high affinity to the mouse and rat MCHR1 with minimal cross-reactivity to other GPCR, ion channels, enzymes, and transporters [1] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1781934-47-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107625A. | |
| (S)-Navlimetostat | (S)-Navlimetostat (example 16-7) is the S-enantiomer of Navlimetostat. (S)-Navlimetostat is a PRMT5/MTA complex inhibitor, with an IC 50 of 7070 nM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (S)-MRTX-1719. CAS No. 2630904-44-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-139611B. | |
| SNC80 | SNC80 (NIH 10815) is a potent, highly selective and non-peptide δ-opioid receptor agonist with a K i of 1.78 nM and an IC 50 of 2.73 nM. SNC80 also selectively activates μ-δ heteromer in HEK293 cells with an EC 50 of 52.8 nM. SNC80 shows antinociceptive, antihyperalgesic and antidepressant?like effects. SNC80 has the potential for multiple headache disorders treatment [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NIH 10815. CAS No. 156727-74-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101202. | |
| sn-Glycero-3-phosphocholine | sn-Glycero-3-phosphocholine (Choline Alfoscerate) is a precursor in the biosynthesis of brain phospholipids and increases the bioavailability of choline in nervous tissue. sn-Glycero-3-phosphocholine (Choline Alfoscerate) has significant effects on cognitive function with a good safety profile and tolerability, and is effective in the treatment of Alzheimer's disease and dementia [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Choline Alfoscerate; Alpha-GPC; L-α-GPC. CAS No. 28319-77-9. Pack Sizes: 500 mg; 1 g; 5 g. Product ID: HY-17552. | |
| sn-Glycero-3-phosphocholine-d9 | sn-Glycero-3-phosphocholine-d 9 is the deuterium labeled sn-Glycero-3-phosphocholine. sn-Glycero-3-phosphocholine (Choline Alfoscerate) is a precursor in the biosynthesis of brain phospholipids and increases the bioavailability of choline in nervous tissue. sn-Glycero-3-phosphocholine (Choline Alfoscerate) has significant effects on cognitive function with a good safety profile and tolerability, and is effective in the treatment of Alzheimer's disease and dementia[1][2]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: Choline Alfoscerate-d9; Alpha-GPC-d9; L-α-GPC-d9. CAS No. 2260669-07-4. Pack Sizes: 1 mg; 5 mg; 500 μg. Product ID: HY-17552S. | |
| sn-Glycerol 3-phosphate | sn-Glycerol 3-phosphate is an important intermediate in glycolysis and lipid metabolism. The cytosolic sn-Glycerol 3-phosphate dehydrogenase (GPDH) consumes NADH to generate sn-Glycerol 3-phosphate from dihydroxyacetone phosphate (DHAP). Glyceroneogenesis is an important supplier of sn-Glycerol 3-phosphate for lipid metabolism [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 17989-41-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg. Product ID: HY-113128. | |
| sn-Glycerol 3-phosphate lithium | sn-Glycerol 3-phosphate lithium is an important intermediate in glycolysis and lipid metabolism. The cytosolic sn-Glycerol 3-phosphate dehydrogenase (GPDH) consumes NADH to generate sn-Glycerol 3-phosphate lithium from dihydroxyacetone phosphate (DHAP). Glyceroneogenesis is an important supplier of sn-Glycerol 3-phosphate lithium for lipid metabolism[1][2]. Uses: Scientific research. Group: Natural products. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-113128A. | |
| (S)-N-Glycidylphthalimide | (S)-N-Glycidylphthalimide is a natural product [1]. Uses: Scientific research. Group: Natural products. CAS No. 161596-47-0. Pack Sizes: 1 g; 5 g. Product ID: HY-I0035. | |
| (S)-Nicardipine | (S)-Nicardipine ((S)-YC-93 free base) is the less active S enantiomer of Nicardipine. Nicardipine is a calcium channel blocker with an IC 50 of 1 μM for blocking cardiac calcium channels. Nicardipine acts as an agent for chronic stable angina and for controlling blood pressure [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (S)-YC-93 free base. CAS No. 76093-36-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12515B. | |
| S-Nitroso-N-acetyl-DL-penicillamine | S-Nitroso-N-acetyl-DL-penicillamine (SNAP) is a nitric oxide donor and acts as a stable inhibitor of platelet aggregation[1][2][3][4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SNAP. CAS No. 67776-06-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-121526. | |
| (S)-Nornicotine | (S)-Nornicotine is a metabolite of nicotine. Uses: Scientific research. Group: Natural products. CAS No. 494-97-3. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-W040430. | |
| SNPB | SNPB is a cleavable linker that is used for making antibody-drug conjugate (ADC). Uses: Scientific research. Group: Signaling pathways. CAS No. 663598-85-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-129365. | |
| SNS-032 | SNS-032 (BMS-387032) is a potent and selective inhibitor of CDK2 , CDK7 , and CDK9 with IC 50 s of 38 nM, 62 nM and 4 nM, respectively. SNS-032 has antitumor effect [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BMS-387032. CAS No. 345627-80-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-10008. | |
| SNS-314 mesylate | SNS-314 mesylate is a potent and selective aurora kinase inhibitor with IC 50 s of 9, 31, and 6 nM for aurora A, B and C, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1146618-41-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12003. | |
| SNX-2112 | SNX-2112 (PF 04928473) is an orally active Hsp90 inhibitor, with a Kd of 16 nM for Hsp90 and IC50s of 30 nM, 30 nM for Hsp90 ? and Hsp90 ?, also induces Her-2 degradation, and inhibits Grp94 and Trap-1, with IC50s of 10 nM, 4.275 ?M and 0.862 ?M, respectively[1]. SNX-2112 (PF 04928473) binds Hsp90 isoforms Hsp90?, Hsp90? and Hsp90b1/Grp94 with Kds of 4 nM, 6 nM and 484 nM, respectively[2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PF-04928473. CAS No. 908112-43-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-10214. | |
| SNX281 | SNX281 is a systemically active non-CDN STING agonist that binds to the STING protein. SNX281 promotes signal transduction of the cGAS-STING pathway, and increases cellular responses to tumor cells. SNX281 activates STING and leads to the production of type I IFNs and proinflammarory cytokines, ultimately stimulating the infilatration of immune cells into the tumor microenvironment. SNX281 enhances anti-tumor immunity, potentially overcoming resistance to checkpoint inhibitors in some cancer. SNX281 can be used in the research for anti-tumor immunity[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2332803-84-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-160406. | |
| SNX-482 | SNX-482, a peptide, is a potent, high affinity, selective and voltage-dependent R-type Ca V 2.3 channel blocker with an IC 50 of 30 nM. SNX-482 has antinociceptive effect [1] [2] [3]. Uses: Scientific research. Group: Peptides. CAS No. 203460-30-4. Pack Sizes: 50 μg. Product ID: HY-P1074. | |
| SNX-5422 | SNX-5422 (PF-04929113), a prodrug of SNX-2112, is an orally active Hsp90 inhibitor, with a K d of 41 nM, and also induces Her-2 degradation, with an IC 50 of 37?nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PF-04929113. CAS No. 908115-27-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10213. | |
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