MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Sapienic acid sodium | Sapienic acid sodium is a fatty acid commonly found on the skin and in mucosa. Sapienic acid sodium has variable antimicrobial activities against Gram-positive and Gram-negative bacteria found on the skin and in the oral cavity. Sapienic acid sodium is active against Streptococcus sanguinis , Streptococcus mitis and Fusobacterium nucleatum with MBC values of 31.3 μg/mL, 375.0 μg/mL and 93.8 μg/mL, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 217477-25-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-130187A. |  |
| Sapitinib | Sapitinib (AZD-8931) is a reversible, ATP competitive EGFR inhibitor of with IC50s of 4, 3 and 4 nM for EGFR, ErbB2 and ErbB3 in cells, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AZD-8931. CAS No. 848942-61-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-13050. | |
| Saponins | Saponins (Saponin) is a class of chemical compound of glycosides found in particular abundance in various plant species. In plants, Saponins may serve as anti-feedants, and to protect the plant against microbes and fungi [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Saponin. CAS No. 8047-15-2. Pack Sizes: 100 mg; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-100597. | |
| Sappanchalcone | Sappanchalcone, a flavonoid isolated from Caesalpinia sappan L., induces caspase-dependent and AIF-dependent apoptosis in human colon cancer cells [1]. Uses: Scientific research. Group: Natural products. CAS No. 94344-54-4. Pack Sizes: 1 mg; 5 mg. Product ID: HY-59001. | |
| Sappanone A | Sappanone A is a homoisoflavanone which exhibits anti-inflammatory effects via modulation of Nrf2 and NF-κB. Sappanone can attenuate allergic airway inflammation in Ovalbumin-induced asthma [1]. Uses: Scientific research. Group: Natural products. CAS No. 102067-84-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-113556. | |
| Sapropterin dihydrochloride | Sapropterin ((6R)-BH4) is an orally active phenylalanine hydroxylase (PAH) cofactor, which is effective in reducing blood phenylalanine concentrations. Sapropterin also drives autoimmunity. Sapropterin can be used in study of phenylketonuria (PKU) [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: (6R)-BH4 dihydrochloride; (6R)-Tetrahydro-L-biopterin dihydrochloride. CAS No. 69056-38-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-A0124A. | |
| Saquinavir | Saquinavir(Ro 31-8959) is an HIV Protease inhibitor used in antiretroviral therapy. Saquinavir is also a SARS-CoV 3CL pro inhibitor with an IC 50 of 1.36 μM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ro 31-8959. CAS No. 127779-20-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17007. | |
| Saquinavir mesylate | Saquinavir Mesylate (Ro 31-8959/003) is an HIV protease inhibitor used in retrovirus research. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ro 31-8959/003. CAS No. 149845-06-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17003. | |
| SAR125844 | SAR125844 is a potent, selective, and ATP-competitive MET kinase inhibitor with the value of IC 50 is 4.2 nM and K i is 2.8 nM. SAR125844 has antitumor activity and can be used for the research of cancer [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1116743-46-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16446. | |
| SAR131675 | SAR131675 is a potent and selective VEGFR3 inhibitor with an IC 50 of 23 nM. SAR131675 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 1433953-83-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15458. | |
| SAR-20347 | SAR-20347 is an inhibitor of TYK2, JAK1, JAK2 and JAK3 with IC50s of 0.6, 23, 26 and 41 nM, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1450881-55-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100895. | |
| SAR247799 | SAR247799 (S1P1 agonist 3) is an oral activity, selective G-protein-biased sphingosine-1 phosphate receptor-1 (S1P1 ) agonist, with EC 50 s rang from 12.6 to 493 nM in S1P1-overexpressing cells and HUVECs. SAR247799 can be used for the research of endothelial protection, including type-2 diabetes, metabolic syndrome [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: S1P1 agonist 3. CAS No. 1315311-14-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-115831. | |
| SAR405 | SAR405 is a first-in-class, selective, and ATP-competitive PI3K class III (PIK3C3) isoform Vps34 inhibitor (IC50=1.2 nM; Kd=1.5 nM). SAR405 inhibits autophagy induced either by starvation or by mTOR inhibition. Anticancer activity[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1523406-39-4. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-12481. | |
| SAR407899 | SAR407899 is a selective, potent and ATP-competitive ROCK inhibitor, with an IC 50 of 135 nM for ROCK-2 , and K i s of 36 nM and 41 nM for human and rat ROCK-2 , respectively. SAR407899 shows stable inhibition of migrasome formation. Uses: Scientific research. Group: Signaling pathways. CAS No. 923359-38-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15687A. | |
| SAR407899 hydrochloride | SAR407899 hydrochloride is a selective, potent and ATP-competitive ROCK inhibitor, with an IC 50 of 135 nM for ROCK-2 , and K i s of 36 nM and 41 nM for human and rat ROCK-2 , respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 923262-96-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15687. | |
| SAR7334 | SAR7334 is a potent and specific TRPC6 inhibitor, inhibiting TRPC6 currents with IC50 of 7.9 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 1333210-07-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15699. | |
| [Sar9,Met(O2)11]-Substance P | [Sar9,Met(O2)11]-Substance P is a tachykinin NK 1 receptor selective agonist. Uses: Scientific research. Group: Peptides. CAS No. 110880-55-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P1012. | |
| [Sar9,Met(O2)11]-Substance P TFA | [Sar9,Met(O2)11]-Substance P TFA is a tachykinin NK 1 receptor selective agonist. Uses: Scientific research. Group: Peptides. CAS No. 2828433-10-7. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-P1012A. | |
| [Sar9] Substance P | [Sar9] Substance P is a potent and selective neurokinin (NK)-1 receptor agonist [1]. Uses: Scientific research. Group: Peptides. CAS No. 77128-75-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1738. | |
| Saracatinib | Saracatinib (AZD0530) is a potent Src family inhibitor with IC 50 s of 2.7 to 11 nM for c-Src , Lck , c-YES , Lyn , Fyn , Fgr , and Blk. Saracatinib shows high selectivity over other tyrosine kinases [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AZD0530. CAS No. 379231-04-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10234. | |
| Sarafloxacin hydrochloride | Sarafloxacin (hydrochloride) (A-56620 (hydrochloride)) is a quinolone antibiotic agent. Uses: Scientific research. Group: Signaling pathways. Alternative Names: A-56620 hydrochloride. CAS No. 91296-87-6. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0343A. | |
| Sarcosine | Sarcosine (N-Methylglycine), an endogenous amino acid, is a competitive glycine transporter type I (GlyT1) inhibitor and N-methyl-D-aspartate (NMDA) receptor co-agonist. Sarcosine increases the glycine concentration, resulting in an indirect potentiation of the NMDA receptor. Sarcosine is commonly used for the research of schizophrenia [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: N-Methylglycine; Sarcosin. CAS No. 107-97-1. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-101037. | |
| Sarcosine oxidase, Bacillus | Sarcosine oxidase, Bacillus (SAO) can catalyze the oxidative demethylation of sarcosine to generate glycine, H 2 O 2 , 5,10-CH 2 -tetrahydrofolate, which are often used in biochemical reactions [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SAO. CAS No. 9029-22-5. Pack Sizes: 10 KU. Product ID: HY-P2861. | |
| Sardomozide dihydrochloride | Sardomozide dihydrochloride is an S-adenosylmethionine decarboxylase ( SAMDC ) inhibitor with an IC 50 of 5 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CGP 48664A. CAS No. 138794-73-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-13746B. | |
| Sarecycline hydrochloride | Sarecycline hydrochloride is an orally active narrow-spectrum tetracycline derivative antibiotic. Sarecycline hydrochloride has anti-inflammatory activity. Sarecycline hydrochloride inhibits the activity of Gram-positive bacteria and several types of keratobacterium acnes. Sarecycline hydrochloride interferes with tRNA accommodation and tethers mRNA to the 70S ribosome. Sarecycline hydrochloride can be used to study moderate to severe acne [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: P-005672 hydrochloride. CAS No. 1035979-44-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg. Product ID: HY-13858A. | |
| Saredutant | Saredutant is a selective NK2 receptor antagonist. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SR 48968; SR 48968C. CAS No. 142001-63-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106910. | |
| Sarilumab | Sarilumab (Anti-Human IL6Rα, Human Antibody) is a human immunoglobulin G1 monoclonal antibody. Sarilumab, a interleukin-6 (IL-6) receptor antagonist, binds to the IL-6 receptor with high affinity and inhibits cis and trans signaling by IL-6, resulting in reduced inflammation. Sarilumab can be used for the research of Rheumatoid arthritis [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Anti-Human IL6Rα, Human Antibody. CAS No. 1189541-98-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9916. | |
| Sarizotan | Sarizotan (EMD 128130) is an orally active serotonin 5-HT 1A receptor and dopamine receptor agonist. Sarizotan (EMD 128130) exhibits IC 50 values of 6.5 nM (rat 5-HT 1A ), 0.1 nM (human 5-HT 1A ), 15.1 nM (rat D 2 ), 17 nM (human D 2 ), 6.8 nM (human D 3 ) and 2.4 nM (human D 4.2 ), respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: EMD 128130. CAS No. 351862-32-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100820. | |
| SARM1-IN-2 | SARM1-IN-2 (Example 82) is a SARM1 inhibitor (IC50 <1 ?M) that inhibits axon regeneration. Axon regeneration refers to the process by which neuronal axons attempt to restore their structure and function after axonal degeneration. SARM1-IN-2 inhibits axon regeneration by reducing or inhibiting the binding of SARM1 to NAD+. SARM1-IN-2 can be used to study axonal degeneration[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2396592-52-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145917. | |
| Saroglitazar | Saroglitazar is a novel peroxisome proliferator-activated receptor ( PPAR ) agonist with predominant PPARα and moderate PPARγ activity with EC 50 values of 0.65 pM and 3 nM in HepG2 cells, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 495399-09-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19937. | |
| Saroglitazar magnesium | Saroglitazar magnesium is a novel peroxisome proliferator-activated receptor ( PPAR ) agonist with predominant PPARα and moderate PPARγ activity with EC 50 values of 0.65 pM and 3 nM in HepG2 cells, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1639792-20-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-19937A. | |
| Sarolaner | Sarolaner (PF-6450567) is an orally active and broad-spectrum ectoparasiticide. Sarolaner is an isoxazoline compound which shows efficacy against fleas and ticks on dogs, with a LC 80 value of 0.3 μg/mL against C. felis and a LC 100 value of 0.003 μg/mL against O. turicata [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PF-6450567. CAS No. 1398609-39-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16730. | |
| Sarpogrelate hydrochloride | Sarpogrelate hydrochloride (MCI-9042) is a selective 5-HT 2 R antagonist, with pK i s of 8.52, 6.57, and 7.43 for 5-HT 2A , 5-HT 2B , and 5-HT 2C receptors, respectively. Sarpogrelate hydrochloride displays selectivity over 5-HT 1 , 5-HT 3 , 5-HT 4 , α 1 -, α 2 - and β-adrenoreceptor, histamine H 1 , H 2 and muscarinic M 3 receptors. Sarpogrelate hydrochloride can be used for the research of vascular disease associated with thrombosis [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MCI-9042. CAS No. 135159-51-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10564. | |
| Sarsasapogenin | Sarsasapogenin is a sapogenin from the Chinese medical herb Anemarrhena asphodeloides Bunge, with antidiabetic, anti-oxidative, anticancer and anti-inflamatory activities. Uses: Scientific research. Group: Natural products. Alternative Names: Parigenin; Sarsagenin. CAS No. 126-19-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0073. | |
| Sarsasapogenin (Standard) | Sarsasapogenin (Standard) is the analytical standard of Sarsasapogenin. This product is intended for research and analytical applications. Sarsasapogenin is a sapogenin from the Chinese medical herb Anemarrhena asphodeloides Bunge, with antidiabetic, anti-oxidative, anticancer and anti-inflamatory activities. Uses: Scientific research. Group: Natural products. CAS No. 126-19-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0073R. | |
| SARS-CoV-2-IN-6 | SARS-CoV-2-IN-6 is a SARS-CoV-2 3CLpro inhibitor that shows the most potent enzyme inhibitory IC 50 value of 73 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 2725749-22-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132886. | |
| SARS-CoV-2-IN-7 | SARS-CoV-2-IN-7 inhibits viral replication with a nanomolar IC 50 value (844 nM) in SARS-CoV-2-infected Vero E6 cells. Uses: Scientific research. Group: Signaling pathways. CAS No. 2570461-66-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-141841. | |
| SARS-CoV-2 Mpro-IN-2 | SARS-CoV-2 Mpro-IN-2 (compound GC-14) is a selective, low cytotoxic and non-covalent M pro inhibitor ( IC 50 =0.40 μM) with good anti-SARS-CoV-2 activity ( EC 50 =1.1 μM). SARS-CoV-2 Mpro-IN-2 can be used in COVID-19 studies [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2768834-39-3. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-151482. | |
| SARS-CoV-2 nsp13-IN-1 | SARS-CoV-2 nsp13-IN-1 (compound C1) is a potent nsp13 (non-structural protein 13) inhibitor. SARS-CoV-2 nsp13-IN-1 only inhibits nsp13 ssDNA + ATPase , with an IC 50 of 6 μM. SARS-CoV-2 nsp13-IN-1 does not inhibit ssDNA - ATPase. SARS-CoV-2 nsp13-IN-1 can be used for COVID-19 research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1005304-44-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-150622. | |
| SARS-CoV-2 nsp14-IN-3 | SARS-CoV-2 nsp14-IN-3 (4975) is an inhibitor of the SARS-CoV-2 Nsp14 N7-Methyltransferase ( IC 50 : 3.5 μM) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2920574-16-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-149321. | |
| SARS-CoV-2 nsp3-IN-1 | SARS-CoV-2 nsp3-IN-1 (Compound 15c) is a Mac1 ( SARS-CoV-2 nsp3 macrodomain ) inhibitor with the IC 50 value of 6.1 μM. SARS-CoV-2 nsp3-IN-1 can inhibit Mac1 ADP-ribosylhydrolase activity. SARS-CoV-2 nsp3-IN-1 demonstrates notable selectivity for coronavirus macrodomains, especially towards SARS-CoV-2 Mac1 [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2892105-43-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-150062. | |
| SARS-CoV-IN-1 | SARS-CoV-IN-1 is an effective inhibitor of SARS-CoV replication. SARS-CoV-IN-1 shows anti-Coronavirus activity with an EC 50 of 4.9 μM in Vero cells. SARS-CoV-IN-1 inhibits the 3D7 and W2 strains of P. falciparum with IC 50 s of 15.4 and 133.2 nM; and IC 90 s of 25.7 and 459.1 nM; respectively. Antimalarial and antiviral activities [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 888958-25-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-135855. | |
| SARS-CoV-IN-2 | SARS-CoV-IN-2 is an effective inhibitor of SARS-CoV replication. SARS-CoV-IN-2 shows anti-Coronavirus activity with an EC 50 of 1.9 μM in Vero cells. SARS-CoV-IN-2 inhibits the 3D7 and W2 strains of P. falciparum with IC 50 s of 21.5 and 30 nM; and IC 90 s of 51.0 and 99.9 nM; respectively. SARS-CoV-IN-2 reduces HIV-1 -induced cytopathic effect with an EC 50 of 2.9 μM in MT-4 cells. Antimalarial and Antiviral Activities [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 888958-26-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-135856. | |
| SARS-CoV-IN-3 | SARS-CoV-IN-3 is an effective inhibitor of SARS-CoV replication. SARS-CoV-IN-3 shows anti-Coronavirus activity with an EC 50 of 3.6 μM in Vero cells. SARS-CoV-IN-3 inhibits the 3D7 and W2 strains of P. falciparum with IC 50 s of 11.7 and 20.4 nM; and IC 90 s of 29.19 and 56 nM; respectively. SARS-CoV-IN-3 reduces HIV-1 -induced cytopathic effect with an EC 50 of 10 μM in MT-4 cells [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 888958-27-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-135858. | |
| Saruparib | Saruparib (AZD5305) is a potent, orally active and selective PARP inhibitor and trapper with IC 50 values of 3 nM and 1400 nM for PARP1 and PARP2, respectively. Saruparib has anti-proliferative activity and inhibits growth in cells with deficiencies in DNA repair [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AZD5305. CAS No. 2589531-76-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132167. | |
| (S)-Atenolol | (S)-Atenolol is a potent beta-adrenoreceptor blocker. (S)-Atenolol has the potential for the research of cardiovascular disorder [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 93379-54-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-17498A. | |
| Satoreotide | Satoreotide (JR11) is a SSTR2 antagonist. Satoreotide is usually conjugated with radiolabeled chelators used in neuroendocrine tumor imaing [1]. Uses: Scientific research. Group: Peptides. Alternative Names: JR11. CAS No. 1801415-23-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P10137. | |
| Satralizumab | Satralizumab, a humanized monoclonal antibody, is a potent Interleukine-6 (IL-6) inhibitor. Satralizumab prevents dTAA formation and progression in rattus norvegicus. Satralizumab can be used for neuromyelitis optica spectrum disorder (NMOSD) and descending thoracic aorta aneurysm (dTAA) research [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 1535963-91-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99112. | |
| Satraplatin | Satraplatin is an alkylating agent, with potent antitumor effect. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BMS182751; BMY45594; JM216. CAS No. 129580-63-8. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17576. | |
| Sauchinone | Sauchinone is a diastereomeric lignan isolated from Saururus chinensis (Saururaceae). Sauchinone inhibits LPS-inducible iNOS, TNF-α and COX-2 expression through suppression of I-κBα phosphorylation and p65 nuclear translocation. Sauchinone has anti-inflammatory and antioxidant activity [1]. Uses: Scientific research. Group: Natural products. CAS No. 177931-17-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 20 mg. Product ID: HY-N0613. | |
| Savolitinib | Savolitinib (AZD-6094) is a potent, highly selective, and orally bioavailable c-Met inhibitor with IC 50 s of 5 nM and 3 nM for c-Met and p-Met, respectively. Savolitinib (AZD-6094) selectively binds to and inhibits the activation of c-Met in an ATP-competitive manner, and disrupts c-Met signal transduction pathways. Antineoplastic activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Volitinib; HMPL-504; AZD-6094. CAS No. 1313725-88-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15959. | |
| Saxagliptin | Saxagliptin (BMS-477118) is a potent, selective, reversible, competitive and orally active dipeptidyl peptidase-4 (DPP-4) ( K i = 0.6-1.3 nM) inhibitor. Saxagliptin has the peotential for type 2 diabetes mellitus research [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BMS-477118. CAS No. 361442-04-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10285. | |
| Saxagliptin hydrate | Saxagliptin hydrate (BMS-477118 hydrate) is a potent, selective, reversible, competitive and orally active dipeptidyl peptidase-4 (DPP-4) ( K i = 0.6-1.3 nM) inhibitor. Saxagliptin hydrate has the peotential for type 2 diabetes mellitus research [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BMS-477118 hydrate. CAS No. 945667-22-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10285A. | |
| Saxagliptin hydrochloride | Saxagliptin hydrochloride (BMS-477118 hydrochloride) is a potent, selective, reversible, competitive and orally active dipeptidyl peptidase-4 (DPP-4) ( K i = 0.6-1.3 nM) inhibitor. Saxagliptin hydrochloride has the peotential for type 2 diabetes mellitus research [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BMS-477118 hydrochloride. CAS No. 709031-78-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16448. | |
| SB-200646A | SB-200646A is the first selective 5-HT 2B/2C over 5-HT 2A receptor antagonist with pK i values of 7.5, 6.9 and 5.2 for 5-HT 2B , 5-HT 2C and 5-HT 2A , respectively. SB-200646A is orally active and has electrophysiological and anxiolytic properties in vivo [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 143797-62-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-103129. | |
| SB 202190 | SB 202190 is a selective p38 MAP kinase inhibitor with IC 50 s of 50 nM and 100 nM for p38α and p38β2, respectively. SB 202190 binds to the ATP pocket of the active recombinant human p38 kinase with a K d of 38 nM. SB 202190 has anti-cancer activity and rescued memory deficits [1] [2]. SB202190 induces autophagy [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 152121-30-7. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 200 mg. Product ID: HY-10295. | |
| SB 202190 hydrochloride | SB 202190 hydrochloride is a selective p38 MAP kinase inhibitor with IC 50 s of 50 nM and 100 nM for p38α and p38β2, respectively. SB 202190 hydrochloride binds to the ATP pocket of the active recombinant human p38 kinase with a K d of 38 nM. SB 202190 hydrochloride has anti-cancer activity [1] [2]. SB202190 hydrochloride induces autophagy [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 350228-36-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10295A. | |
| SB 204741 | SB 204741 is a selective and high affinity 5-HT2B antagonist with a pKi value of 7.1[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 152239-46-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103153. | |
| SB 204990 | SB 204990 is a potent and specific inhibitor of ATP citrate lyase (ACLY) enzyme. Uses: Scientific research. Group: Signaling pathways. CAS No. 154566-12-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-16450. | |
| SB 206553 hydrochloride | SB 206553 hydrochloride is a high affinity, selective and orally active 5-HT 2B / 5-HT 2C receptor antagonist (rat 5-HT 2B pA2 = 8.89, human 5-HT 2C pKi = 7.92) [1]. SB 206553 possesses anxiolytic-like properties [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1197334-04-5. Pack Sizes: 5 mg. Product ID: HY-103135. | |
| SB-216 | SB-216 is a potent tubulin polymerization inhibitor. SB-216 shows strong antiproliferative potency in a panel of human cancer cell lines, including melanoma, lung cancer, and breast cancer. SB-216 can be used for cancer research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2756818-39-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-144898. | |
| SB 216763 | SB 216763 is potent, selective and ATP-competitive GSK-3 inhibitor with IC 50 s of 34.3 nM for both GSK-3α and GSK-3&beta. Uses: Scientific research. Group: Signaling pathways. CAS No. 280744-09-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12012. | |
| SB-222200 | SB-222200 is a potent, selective, orally active and blood-brain barrier (BBB) penetrant NK-3 receptor antagonist. SB-222200 is developed for central nervous system (CNS) disorders [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 174635-69-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-15722. | |
| SB-224289 hydrochloride | SB-224289 hydrochloride is a selective 5-HT1B receptor antagonist, with anxiolytic effect. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SB-224289A. CAS No. 180084-26-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101105A. | |
| SB225002 | SB225002, a potent, selective and non-peptide CXCR2 antagonist, inhibits 125I-IL-8 binding to CXCR2 with an IC50 of 22 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 182498-32-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-16711. | |
| SB 239063 | SB 239063 is a potent, selective and orally active p38 MAPK inhibitor, exhibits an IC50 of 44 nM for recombinant purified human p38?, with equipotent inhibitory activity against p38? and p38?. SB 239063 has no effect on p38? or p38?. With anti-asthma activity and also be used to enhance memory which is impaired due to aging or medical conditions, such as, AD[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 193551-21-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-11068. | |
| SB 242235 | SB-242235 is a potent and selective p38 MAP kinase inhibitor, with an IC 50 of 1.0?μM in primary human chondrocytes [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 193746-75-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18306. | |
| SB-258585 hydrochloride | SB-258585 is a high affinity ligand for the 5-HT 6 receptor. SB-258585 binds highly to a single receptor population in a human cell line that recombines 5-HT 6 receptors. SB-258585 can be used to label recombinant and natural 5-HT 6 receptor [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1216468-02-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-103141. | |
| SB-269970 | SB-269970 is a potent, selective and brain-penetrant 5-HT7 receptor antagonist with a pK i of 8.3. SB-269970 exhibits >50-fold selectivity against other 5-HT receptors [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 201038-74-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-15370. | |
| SB-269970 hydrochloride | SB-269970 hydrochloride is a potent, selective and brain-penetrant 5-HT7 receptor antagonist with a pK i of 8.3. SB-269970 hydrochloride exhibits >50-fold selectivity against other 5-HT receptors [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SB-269970A. CAS No. 261901-57-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-15370A. | |
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