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S 17092
S 17092 (S 17092-1) is an orally active cerebral prolyl-endopeptidase (PEP) inhibitor with an IC 50 of 1.2 nM. S 17092 inhibits cell apoptosis. S 17092 mechanism of action is to inhibit the activity of PEP, slowing down the degradation of neuroactive peptides and thus enhancing memory function. S 17092 can be used for the research of memory impairment and cognitive disorders associated with cerebral aging [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: S 17092-1. CAS No. 176797-26-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15114.
S186
S186 is a new type of strontium-specific chelator. Uses: Scientific research. Group: Signaling pathways. CAS No. 97759-16-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13950.
S 18986
S 18986 is a selective, orally active, brain penetrant positive allosteric modulator of AMPA-type receptors. S 18986 shows cognitive enhancing properties in rodents. S 18986 activates the release of noradrenaline and acetylcholine in rat hippocampus and enhances rat memory in object-recognition tests [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 175340-20-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10936.
S19-1035
S19-1035 is a highly potent and specific aldo-keto reductase 1C3 (AKR1C3) inhibitor. S19-1035 inhibits AKR1C3 with an IC50 value of 3.04 nM. S19-1035 can be used for the research of tumor[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2986319-18-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-152189.
(S)-1-Boc-3-aminopiperidine
(S)-1-Boc-3-aminopiperidine is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: (S)-(+)-3-Amino-1-boc-piperidine. CAS No. 625471-18-3. Pack Sizes: 10 g; 25 g. Product ID: HY-40029.
(S)-1-Boc-3-aminopyrrolidine
(S)-1-Boc-3-aminopyrrolidine is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 147081-44-5. Pack Sizes: 5 g; 10 g. Product ID: HY-40098.
(S)-1-Boc-3-hydroxypiperidine
(S)-1-Boc-3-hydroxypiperidine is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 143900-44-1. Pack Sizes: 10 mM * 1 mL; 25 g; 50 g. Product ID: HY-40023.
(S)-1-Boc-3-methylpiperazine
(S)-1-Boc-3-methylpiperazine is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 147081-29-6. Pack Sizes: 10 mM * 1 mL; 5 g. Product ID: HY-40040.
S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate is a glutathione cleavable ADC linker used for the antibody-drug conjugates (ADCs) and refers to the Alkyl-Chain composition. S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate is the linker portions of the molecules employed for mAb attachment purposes [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2127875-65-2. Pack Sizes: 50 mg; 100 mg; 250 mg. Product ID: HY-129942.
S1P1 agonist 1
S1P1 Agonist 1 is a S1P1 agonist with immunomodulatory activities. Uses: Scientific research. Group: Signaling pathways. CAS No. 1220973-37-4. Pack Sizes: 2 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-104069.
(S)-(-)-1-Phenylethanamine
(S)-(-)-1-Phenylethanamine (S-(-)-α-Phenylethylamine; L-(-)-α-Methylbenzylamine) is a S-isomer of 1-Phenylethanamine (HY-W012848). 1-Phenylethanamine is a potential central nervous system stimulant and can be used to synthesize the tyrosine kinase inhibitor CLM3 (HY-164413) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: S-(-)-α-Phenylethylamine; L-(-)-α-Methylbenzylamine. CAS No. 2627-86-3. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-75095.
S1PR1 modulator 1
S1PR1 modulator 1 is a selective S1PR1 inhibitor, with a pIC 50 of 7.6, with >40- and >80-fold selectivity, over the other S1PR isoforms S1PR2/3/4 [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2328109-05-1. Pack Sizes: 1 mg; 5 mg. Product ID: HY-126145.
S1RA
S1RA (E-52862) is a highly selective σ1 receptor (σ1R) antagonist with K i s of 17 nM and 23.5 nM for human σ1R and guinea pig σ1R, respectively. S1RA has Moderate antagonistic activity for human 5-HT 2B receptor (K i = 328 nM). S1RA has antinociceptive effects in neuropathic pain models. S1RA prevents mechanical and cold hypersensitivity in Oxaliplatin (HY-17371)-treated mice [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: E-52862. CAS No. 878141-96-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-18099.
S1RA hydrochloride
S1RA (E-52862) hydrochloride is an orally active and selective sigma-1 receptor ( σ1R ) antagonist with a K i value of 17 nM. S1RA hydrochloride shows good selectivity against σ2R (K i >1000 nM). S1RA hydrochloride is a human 5-HT2B receptor antagonist with an IC 50 value of 4.7 μM. S1RA hydrochloride inhibits neuropathic pain and activity-induced spinal sensitization [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: E-52862 hydrochloride. CAS No. 1265917-14-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-18099A.
S2101
S2101 is a lysine-specific demethylase 1 ( LSD1 ) inhibitor with an IC 50 of 0.99 μM, K i of 0.61 μM and K inact /K i of 4560 M/s [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1239262-36-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110277.
S2116
S2116, a N-alkylated tranylcypromine (TCP) derivative, is a potent lysine-specific demethylase 1 (LSD1) inhibitor. S2116 increases H3K9 methylation and reciprocal H3K27 deacetylation at super-enhancer regions. S2116 induces apoptosis in TCP-resistant T-cell acute lymphoblastic leukemia (T-ALL) cells by repressing transcription of the NOTCH3 and TAL1 genes. S2116 significantly retardes the growth of T-ALL cells in xenotransplanted mice [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2262489-89-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136522.
(S) -2- (2- ( (tert-Butoxycarbonyl) amino) propanamido) acetic acid is a Glycine (HY-Y0966) derivative [1]. Uses: Scientific research. Group: Peptides. CAS No. 28782-78-7. Pack Sizes: 5 g. Product ID: HY-W019684.
S-23
S-23 is an orally active selective androgen receptor modulator (SARM) with a K i of 1.7 nM. S-23 induces androgen receptor (AR)-mediated transcriptional activation in CV-1 cells. S-23 increases prostate, seminal vesicle, and levator ani muscle weights in castrated rats [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1010396-29-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112257.
S 24795
S 24795 is a partial agonist of α7 nAChR and improves mnemonic function in aged mice for the research of aging-related memory disturbances [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 304679-75-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-11053.
S26131
S26131 (compound 5) is a potent and selective MT1 melatoninergic ligand, and the Ki values are 0.5 and 112 nM for MT1 and MT2, respectively. S26131 behaves as an MT1 and MT2 antagonist[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 296280-56-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-122136.
(S)-2,6-Bis((tert-butoxycarbonyl)amino)hexanoic acid is a polypeptide derivative, can be used to synthesis multifunctional amphiphilic peptide dendrimer, as a nonviral gene vectors, realizes the method in cancer research. (S)-2,6-Bis((tert-butoxycarbonyl)amino)hexanoic acid also involves in the synthesis of an organic substance that increases the luminescence intensity of alkaline phosphatase substrates[1][2]. Uses: Scientific research. Group: Peptides. CAS No. 2483-46-7. Pack Sizes: 10 g; 25 g; 50 g; 100 g. Product ID: HY-W007599.
S29434
S29434 (NMDPEF) is a potent, competitive, selective and cell-permeable inhibitor of quinone reductase 2 (QR2) , with IC 50 s ranging from 5 to 16 nM for human QR2 at different organizational levels, and has good selectivity for QR2 over QR1. S29434 induces autophagy and inhibits QR2-mediated ROS production [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NMDPEF. CAS No. 874484-20-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122614.
(S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-5-(tert-butoxy)-5-oxopentanoic acid is a glutamic acid derivative [1]. Uses: Scientific research. Group: Peptides. CAS No. 71989-18-9. Pack Sizes: 100 g. Product ID: HY-Y0134.
(S)-2-Aminohexanedioic acid
(S)-2-Aminohexanedioic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 1118-90-7. Pack Sizes: 1 g; 5 g. Product ID: HY-W013665.
(S)-2-Hydroxybutanoic acid
(S)-2-Hydroxybutanoic acid is the S-enantiomer of 2-Hydroxybutanoic acid. 2-Hydroxybutanoic acid, a coproduct of protein metabolism, is an insulin resistance (IR) biomarker[1]. Uses: Scientific research. Group: Natural products. CAS No. 3347-90-8. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g. Product ID: HY-W018499.
(S)-2-(Methylamino)-3-phenylpropanoic acid
(S)-2-(Methylamino)-3-phenylpropanoic acid is a phenylalanine derivative [1]. Uses: Scientific research. Group: Peptides. CAS No. 2566-30-5. Pack Sizes: 5 g; 10 g; 25 g; 100 g. Product ID: HY-W005388.
(S)-(+)-2-Phenylglycine methyl ester hydrochloride is a Glycine (HY-Y0966) derivative [1]. Uses: Scientific research. Group: Peptides. CAS No. 15028-39-4. Pack Sizes: 100 g; 500 g. Product ID: HY-W019714.
(S)-(+)-2-Phenylglycinol
(S)-(+)-2-Phenylglycinol is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 20989-17-7. Pack Sizes: 5 g. Product ID: HY-41414.
S 3304
S 3304 is a novel matrix metalloproteinases ( MMP ) inhibitor specific for MMP-2 and MMP-9. S 3304 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 203640-27-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106992.
(S)-3,5-DHPG
(S)-3,5-DHPG is a weak, but selective group I metabotropic glutamate receptors (mGluRs) agonist with K i values of 0.9 μM and 3.9 μM for mGluR1a and mGluR5a, respectively [1]. (S)-3,5-DHPG exhibits anxiolytic activity in rats subjected to hypoxia [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 162870-29-3. Pack Sizes: 10 mM * 1 mL; 5 mg. Product ID: HY-12598.
S 38093
S 38093 is a brain-penetrant, orally active antagonist of H3 receptor , with K i s of 8.8, 1.44 and 1.2 μM for rat, mouse and human H3 receptors, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 862896-30-8. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-104003.
S)-(-)-3-Boc-2,2-dimethyloxazolidine-4-carboxaldehyde is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 102308-32-7. Pack Sizes: 1 g; 5 g. Product ID: HY-69348.
(S)-3-Boc-aminopiperidine
(S)-3-Boc-aminopiperidine is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 216854-23-8. Pack Sizes: 10 mM * 1 mL; 25 g. Product ID: HY-40028.
(S)-3-(Boc-amino)pyrrolidine
(S)-3-(Boc-amino)pyrrolidine is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 122536-76-9. Pack Sizes: 10 mM * 1 mL; 10 g; 25 g. Product ID: HY-79691.
(S)-3-Hydroxybutanoic acid
(S)-3-Hydroxybutanoic acid is a normal human metabolite, that has been found elevated in geriatric patients remitting from depression. In humans, 3-Hydroxybutyric acid is synthesized in the liver from acetyl-CoA, and can be used as an energy source by the brain when blood glucose is low. Uses: Scientific research. Group: Natural products. Alternative Names: (S)-β-Hydroxybutanoic acid; L-(+)-3-Hydroxybutyric acid; L-β-Hydroxybutyric acid. CAS No. 6168-83-8. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 500 mg. Product ID: HY-W050031.
S3QEL-2
S3QEL-2, a suppressor of superoxide production from mitochondrial complex III, potently and selectively suppresses site IIIQo superoxide production ( IC 50 =1.7 μM). S3QEL-2 does not affect oxidative phosphorylation, and normal electron flux. S3QEL-2 inhibits HIF-1α accumulation [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 890888-12-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-110282.
(S)-4-Benzyl-2-oxazolidone
(S)-4-Benzyl-2-oxazolidinone is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: (-)-4-Benzyl-2-oxazolidinone. CAS No. 90719-32-7. Pack Sizes: 25 g. Product ID: HY-41882.
(S)-4-Isopropyl-2-oxazolidinone
(S)-4-Isopropyl-2-oxazolidinone is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 17016-83-0. Pack Sizes: 10 mM * 1 mL; 10 g; 25 g. Product ID: HY-W002062.
(S)-4-Phenyloxazolidin-2-one
(S)-4-Phenyloxazolidin-2-one is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: (S)-(+)-4-Phenyl-2-oxazolidinone. CAS No. 99395-88-7. Pack Sizes: 50 g. Product ID: HY-W019727.
(S)-(-)-5-Fluorowillardiine hydrochloride
(S)-(-)-5-Fluorowillardiine hydrochloride is a potent and specific AMPAR agonist. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (5S)-Fluorowillardiine hydrochloride; (S)-5-Fluorowillardiine hydrochloride. CAS No. 1321546-70-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-16713A.
S63845
S63845 is a potent and selective myeloid cell leukemia 1 (MCL1) inhibitor with a Kd of 0.19 nM for human MCL1[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1799633-27-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100741.
S6821
S6821 is a TAS2R8 antagonist with IC 50 value of 0.035 μM. S6821 is not found to be mutagenic or disruptive in vitro, nor is it found to induce micronucleus in bone marrow polychromatic erythrocytes in vivo [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1119831-25-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-139899.
S7
S7 is an IL-6 receptor antagonist and inhibits the binding between IL-6 and IL-6R. S7 can inhibit angiogenesis and tumor growth [1]. Uses: Scientific research. Group: Peptides. CAS No. 853248-13-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P10284.
S961 acetate
S961 acetate is an high-affinity and selective insulin receptor (IR) antagonist with IC50s of 0.048, 0.027, and 630 nM for HIR-A, HIR-B, and human insulin-like growth factor I receptor (HIGF-IR) in SPA-assay, respectively[1]. Uses: Scientific research. Group: Peptides. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P2093B.
Sabatolimab
Sabatolimab (MBG453) is a high-affinity, humanized, IgG4 (S228P) antibody targeting TIM-3 , an inhibitory receptor that regulates adaptive and innate immune responses. Sabatolimab is a potential immunosuppression agent that can target TIM-3 on immune and myeloid cells [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: MBG453. CAS No. 2252262-24-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99044.
Sabcomeline hydrochloride
Sabcomeline (SB-202026) hydrochloride is a potent and functionally selective muscarinic M1 receptor partial agonist that improve cognition. Sabcomeline hydrochloride can be used for Alzheimer's disease research[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SB-202026 hydrochloride; Memric hydrochloride. CAS No. 159912-58-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106432A.
Sabeluzole
Sabeluzole (R 58735), a benzothiazol derivative, has antiischemic, antiepileptic, and cognitive-enhancing properties. Sabeluzole protects rat hippocampal neurons against NMDA- and glutamate-induced neurotoxicity via preventing tau expression. Sabeluzole enhances memory in rats, and prevents the amnesic effect of Chlordiazepoxide. Sabeluzole can be used fro research of Alzheimer's disease [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: R 58735. CAS No. 104383-17-7. Pack Sizes: 5 mg; 10 mg. Product ID: HY-105022.
Sabinene
Sabinene is an naturally occurring bicyclic monoterpene which can be used as flavorings, perfume additives, fine chemicals, and advanced biofuels. Sabinene is also an orally active compound to attenuates skeletal muscle atrophy and regulates ROS-mediated MAPK/MuRF-1 pathways [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 3387-41-5. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-108943.
Sabizabulin
VERU-111 (ABI-231) is a potent and orally active α and β tubulin inhibitor, which displays strong antiproliferative activity, with an average IC 50 of 5.2 nM against panels of melanoma and prostate cancer cell lines. VERU-111 (ABI-231) suppresses tumor growth and metastatic phenotypes of cervical cancer cells via targeting HPV E6 and E7, and has potential for the treatment of prostate cancer [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: VERU-111; ABI-231. CAS No. 1332881-26-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-120599.
Saccharic acid
Saccharic acid is a competitive inhibitor of β-glucuronidase. Saccharic acid considerably retards hydrolysis of the glucuronide of 'l-ortho-hydroxyphenylazo-2-naph-thol' by frozen mouse kidney sections, but has no effect on liver regeneration following damage and on growth in infant mice [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 87-73-0. Pack Sizes: 25 mg; 50 mg. Product ID: HY-W345885.
Saccharin
Saccharin is an orally active, non-caloric artificial sweeteners (NAS). Saccharin has bacteriostatic and microbiome-modulating properties [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 81-07-2. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-Y0272.
Saccharin 1-methylimidazole
Saccharin 1-methylimidazole is an activator for DNA/RNA Synthesis. Uses: Scientific research. Group: Signaling pathways. CAS No. 482333-74-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112060.
Saccharin sodium
Saccharin sodium is an orally active, non-caloric artificial sweeteners (NAS). Saccharin sodium has bacteriostatic and microbiome-modulating properties [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 128-44-9. Pack Sizes: 500 mg. Product ID: HY-B1390A.
Saccharin sodium hydrate
Saccharin sodium hydrate is an orally active, non-caloric artificial sweeteners (NAS). Saccharin sodium hydrate has bacteriostatic and microbiome-modulating properties [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 82385-42-0. Pack Sizes: 500 mg; 1 g. Product ID: HY-B1390B.
Saccharopine
Saccharopine (L-Saccharopine), a lysine degradation intermediate, is a mitochondrial toxin. Lysine and α-ketoglutarate are converted into Saccharopine by the lysine-ketoglutarate reductase. Saccharopine is then oxidized to α-aminoapidate semialdehyde and glutamate by the saccharopine dehydrogenase. Saccharopine impairs development by disrupting mitochondrial homeostasis [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: L-Saccharopine. CAS No. 997-68-2. Pack Sizes: 1 mg. Product ID: HY-W040307.
Saccharopine hydrochloride
Saccharopine (L-Saccharopine) hydrochloride, a lysine degradation intermediate, is a mitochondrial toxin. Lysine and ?-ketoglutarate are converted into Saccharopine hydrochloride by the lysine-ketoglutarate reductase. Saccharopine hydrochloride is then oxidized to ?-aminoapidate semialdehyde and glutamate by the saccharopine dehydrogenase. Saccharopine hydrochloride impairs development by disrupting mitochondrial homeostasis[1][2][3]. Uses: Scientific research. Group: Natural products. Alternative Names: L-Saccharopine hydrochloride. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W040307B.
Sacituzumab
Sacituzumab is a humanized IgG1 monoclonal antibody targeting Trophoblast cell surface antigen 2 (TROP2). Sacituzumab demonstrates a lack of antitumor effects alone and does not inhibit the function of TROP-2 during tumor metastasis, binding to the linear epitopes of TROP-2 protein. Sacituzumab is used for the synthesis of antibody-drug conjugates (ADC) drugs. Antibody-drug conjugates with sacituzumab (sacituzumab govitecan) (HY-132254) targeting TROP-2 have been approved for the field of triple-negative breast cancer [1] [2] [3] [4]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 1796566-95-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99045.
Sacituzumab govitecan
Sacituzumab govitecan (IMMU-132) is an antibody-drug conjugate (ADC) targeting Trop-2 for delivery of SN-38. Sacituzumab govitecan shows anticancer activity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: IMMU-132. CAS No. 1491917-83-9. Pack Sizes: 1 mg; 5 mg. Product ID: HY-132254.
Sacituzumab govitecan (solution)
Sacituzumab govitecan (IMMU-132) is an antibody-drug conjugate (ADC) targeting Trop-2 for delivery of SN-38. Sacituzumab govitecan shows anticancer activity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: IMMU-132 (solution). CAS No. 1491917-83-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132254A.
Sacituzumab tirumotecan
Sacituzumab tirumotecan (SKB264/MK-2870) is a TROP2 ADC. Sacituzumab tirumotecan can be used for the research of triple-negative breast cancer (TNBC) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SKB264; MK-2870. CAS No. 2768350-77-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-164789.
Sacubitril
Sacubitril (AHU-377) is a potent and orally active NEP (neprilysin) inhibitor with an IC 50 of 5 nM. Sacubitril is a component of the heart failure medicine LCZ696. Sacubitril can be used for the research of heart failure, hypertension and COVID-19 [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AHU-377. CAS No. 149709-62-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15407.
Sacubitrilat
Sacubitrilat (Desethyl Sacubitril) is an active neprilysin ( NEP ) inhibitor. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Desethyl Sacubitril; LBQ-657. CAS No. 149709-44-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17620.
Sacubitril sodium
Sacubitril sodium is a potent and orally active NEP (neprilysin) inhibitor, with an IC 50 of 5 nM. Sacubitril sodium enhances the tone of the natriuretic peptide (NP) system and exerts significant antihypertensive effects. Sacubitril sodium is a component of the heart failure medicine LCZ696. Sacubitril sodium can be used for the research of heart failure, hypertension and COVID-19 [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AHU-377 sodium. CAS No. 149690-05-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15407B.
Sacubitril/Valsartan
Sacubitril/Valsartan (LCZ696), comprised Valsartan and Sacubitril (AHU377) in 1:1 molar ratio, is a first-in-class, orally bioavailable, and dual-acting angiotensin receptor-neprilysin (ARN) inhibitor for hypertension and heart failure [1] [2] [3]. Sacubitril/Valsartan ameliorates diabetic cardiomyopathy by inhibiting inflammation, oxidative stress and apoptosis [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LCZ696. CAS No. 936623-90-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-18204A.
S-Adenosyl-DL-methionine
S-Adenosyl-DL-methionine is a derivative of Ademetionine (HY-B0617). Ademetionine is an intermediate metabolite of methionine [1]. Uses: Scientific research. Group: Natural products. CAS No. 17176-17-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-126126.
S-Adenosyl-L-methionine chloride dihydrochloride
S-Adenosyl-L-methionine (S-Adenosyl methionine) chloride dihydrochloride is a methyl donor and cofactor [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: S-Adenosyl methionine chloride dihydrochloride; Ademetionine chloride dihydrochloride; AdoMet chloride dihydrochloride. CAS No. 86867-01-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-14614A.
S-Adenosyl-L-methionine-d3
S-Adenosyl-L-methionine-d3 (S-Adenosyl methionine-d3) is the deuterated product of S-Adenosyl-L-methionine (HY-B0617). S-Adenosyl-L-methionine (S-Adenosyl methionine) is an orally active methyl group donor. S-Adenosyl-L-methionine is a dietary supplement with potent antidepressant effects. S-Adenosyl-L-methionine also has anti?proliferative, pro?apoptotic and anti?metastatic roles in cancers. S-Adenosyl-L-methionine has the potential for, cancer, liver disease and osteoarthritis research[1][2][3]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: S-Adenosyl methionine-d3; Ademetionine-d3; AdoMet-d3. CAS No. 68684-40-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-B0617S.
S-Adenosyl-L-methionine disulfate tosylate
S-Adenosyl-L-methionine (Ademetionine) disulfate tosylate is the disulfate tosylate form of S-Adenosyl-L-methionine (HY-B0617). S-Adenosyl-L-methionine disulfate tosylate is an orally active methyl group donor. S-Adenosyl-L-methionine disulfate tosylate is a dietary supplement with potent antidepressant effects. S-Adenosyl-L-methionine disulfate tosylate also has anti?proliferative, pro?apoptotic and anti?metastatic roles in cancers. S-Adenosyl-L-methionine disulfate tosylate has the potential for, cancer, liver disease and osteoarthritis research[1][2][3]. Uses: Scientific research. Group: Natural products. Alternative Names: Ademetionine disulfate tosylate; S-Adenosyl methionine disulfate tosylate; AdoMet disulfate tosylate. CAS No. 97540-22-2. Pack Sizes: 10 mM * 1 mL; 100 mg; 250 mg; 500 mg. Product ID: HY-W017770.
S-Adenosyl-L-methionine tosylate
S-Adenosyl-L-methionine tosylate is produced endogenously from methionine and ATP by action of the enzyme methionine adenosyltransferase and is an important orally active methyl group donor. S-Adenosyl-L-methionine tosylate is a dietary supplement with potent antidepressant and analgesic effects, and has the potential for liver disease and osteoarthritis research [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: S-Adenosyl methionine tosylate; Ademetionine tosylate; AdoMet tosylate. CAS No. 52248-03-0. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 500 mg. Product ID: HY-B0617A.
SAE-14
SAE-14 (compound SAE-14) is a potent, specific GPR183 antagonist with an IC 50 value of 28.5 nM, can antagonize 7α, 25-OHC - induced calcium mobilization with IC 50 value below 50 nM in HL-60 cells. GPR183 antagonist-1 can reverse allodynia in mice [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GPR183 antagonist-1. CAS No. 1241280-25-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-147222.